MCID: ANX002
MIFTS: 75

Anxiety Disorder malady

Neuronal diseases category

Summaries for Anxiety Disorder

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8Disease Ontology, 33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Fear and anxiety are part of life. you may feel anxious before you take a test or walk down a dark street. this kind of anxiety is useful - it can make you more alert or careful. it usually ends soon after you are out of the situation that caused it. but for millions of people in the united states, the anxiety does not go away, and gets worse over time. they may have chest pains or nightmares. they may even be afraid to leave home. these people have anxiety disorders. types include panic disorder obsessive-compulsive disorder post-traumatic stress disorder phobias generalized anxiety disorder treatment can involve medicines, therapy or both. nih: national institute of mental health

MalaCards: Anxiety Disorder, also known as anxiety disorders, is related to generalized anxiety disorder and panic disorder. An important gene associated with Anxiety Disorder is HTR1A (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled), and among its related pathways are Citalopram Pathway, Pharmacokinetics and Enzymatic degradation of dopamine by COMT. The drugs amobarbital and diphenhydramine hydrochloride and the compounds mianserin and venlafaxine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are renal/urinary system and muscle.

Disease Ontology:8 A cognitive disorder that involves an excessive, irrational dread of everyday situations.

Wikipedia:63 Anxiety disorders are a group of mental disorders characterized by excessive feelings of anxiety and... more...

Aliases & Classifications for Anxiety Disorder

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Sources:
8Disease Ontology, 22GTR, 10DISEASES, 44Novoseek, 60UMLS, 33MedlinePlus, 56SNOMED-CT, 34MeSH, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

anxiety disorder 8 22 10
anxiety disorders 44 60
anxiety neurosis 60
anxiety state 8
anxiety 33


External Ids:

Disease Ontology8 DOID:2030
MeSH34 D001008
NCIt39 C2878
ICD1025 F41.8, F41.9

Related Diseases for Anxiety Disorder

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Anxiety Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 424)
idRelated DiseaseScoreTop Affiliating Genes
1generalized anxiety disorder31.9HTR1A, SLC6A4, TSPO
2panic disorder31.2SLC6A4, CRH, HTR3A, HTR1A, CCKBR, TSPO
3social phobia31.0SLC6A4, MAOA, OXT, HTR3A, HTR1A, COMT
4mood disorder30.9NPY, HTR2A, HTR3A, HTR1A, HTR2C, COMT
5bipolar disorder30.8HTR1A, SLC6A4
6personality disorder30.8DRD4, MAOA, SLC6A3, SLC6A4, TPH1, TPH2
7obsessive-compulsive disorder30.8HTR1A, COMT, HTR3A, HTR2A, DRD4, TPH2
8agoraphobia30.7SLC6A2, MAOA, HTR1A, CCKBR
9alcohol dependence30.6SLC6A4, CNR1, MAOA, CRH, DRD4, NPY
10dysthymic disorder30.4HTR2A, MAOA
11substance abuse30.3SLC6A4, SLC6A3, CNR1, CRH, DRD4
12nicotine dependence30.3DRD4, SLC6A4
13antisocial personality disorder30.3HTR2A, MAOA, SLC6A3, SLC6A4
14attention deficit hyperactivity disorder30.3DRD4, SLC6A3
15eating disorder30.3SLC6A4, SLC6A3, CNR1, CRH, NPY, HTR2A
16psychotic disorder30.3COMT, HTR2C, HTR1A, HTR3A, TPH2, TPH1
17migraine30.2TPH1, SLC6A4, SLC6A3, CNR1, MAOA, DRD4
18irritable bowel syndrome30.2HTR3A, CRH, SLC6A4, TPH1
19alcohol abuse30.2SLC6A4, SLC6A3, COMT
20narcolepsy30.2COMT, HTR2A
21drug dependence30.2MAOA, CNR1, SLC6A4, SLC6A3
22withdrawal disorder30.2CRH, CNR1
23schizophrenia30.2COMT, HTR2A
24anorexia nervosa30.2HTR2A, HTR3A, HTR1A, HTR2C, COMT, TPH1
25hepatitis30.1COMT
26breast cancer30.1CNR1, OXT, HTR3A, COMT
27obesity30.1DRD4, NPY, HTR2A, HTR1A, HTR2C, CCKBR
28pathological gambling30.0DRD4, SLC6A3
29borderline personality disorder30.0TPH1, SLC6A4, MAOA, OXT
30conduct disorder30.0COMT, DRD4, MAOA, SLC6A3, SLC6A4
31dementia30.0COMT, HTR1A, HTR3A, HTR2A, MAOA, SLC6A3
32substance dependence30.0COMT, DRD4, CNR1, SLC6A3, SLC6A4, TPH1
33premature ejaculation30.0SLC6A4, HTR1A
34dermatitis30.0HARS
35alzheimer's disease30.0COMT, HTR2C, HTR1A, HTR2A, NPY, DRD4
36melancholia29.9CRH, MAOA
37bulimia nervosa29.9SLC6A4, MAOA, NPY, HTR2A, HTR3A, COMT
38dyspepsia29.8HTR3A
39neuroleptic malignant syndrome29.8HTR1A
40chronic fatigue syndrome29.8SLC6A4, MAOA, CRH, HTR1A
41hypertension29.8SLC6A4, RGS2, CRH, NPY
42schizoaffective disorder29.8COMT, HTR2A, DRD4, SLC6A4
43autistic disorder29.8HTR1A, HTR3A, HTR2A, OXT, SLC6A4
44myocardial infarction29.8COMT, HTR3A, HTR2A, NPY, CNR1, SLC6A4
45cannabis dependence29.8CNR1
46opiate dependence29.8CCKBR
47parkinson's disease29.8DRD4, HTR2A, HTR3A, HTR1A, HTR2C, CCKBR
48asthma29.8TSPO, CNR1, HTR2A
49paranoid schizophrenia29.8COMT
50ischemia29.8SLC6A3, CNR1, HTR1A, SLC6A2

Graphical network of the top 20 diseases related to Anxiety Disorder:



Diseases related to anxiety disorder

Clinical Features for Anxiety Disorder

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Drugs & Therapeutics for Anxiety Disorder

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Anxiety Disorder

Drug clinical trials:

Search ClinicalTrials for Anxiety Disorder

Search NIH Clinical Center for Anxiety Disorder

Highlights from CenterWatch's Drugs in Clinical Trials Database for Anxiety Disorder:

idCompanyCompoundMechanismPhase
1Ironwood PharmaceuticalsIW-2143/BNC210A small molecule anxiolyticI
2Pherin PharmaceuticalsAloradine nasal sprayAn intranasal spray that acts with rapid-onset on peripheral receptors from nasal chemosensory neurons IIb
3Janssen Pharmaceuticals/Addex PharmaceuticalsJNJ-40411813A mGluR2 positive allosteric modulatorII

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Anxiety Disorder

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Sources:
22GTR
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Genetic tests related to Anxiety Disorder:

id Genetic test Affiliating Genes
1 Anxiety22

Anatomical Context for Anxiety Disorder

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32MalaCards
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MalaCards organs/tissues related to Anxiety Disorder:

32
Heart, Testes, Brain, Cortex, Amygdala, Cingulate cortex, Prefrontal cortex, Eye, Thyroid, Prostate, Liver, Hypothalamus, Temporal lobe, Lung, Fetal brain, Monocytes, Ovary, Pituitary

Animal Models for Anxiety Disorder or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Anxiety Disorder:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000536710.1RGS2, OXT, NPY, HTR3A, CCKBR, COMT
2MP:000536910.0HTR2C, HTR3A, HTR2A, RGS2, SLC6A3, SLC6A4
3MP:00053859.9COMT, CCKBR, HTR1A, OXT, MAOA, RGS2
4MP:00107719.9CCKBR, HTR2C, HTR3A, CRH, OXT, CNR1
5MP:00053789.9NPY, HTR3A, HTR2C, CCKBR, CRH, CNR1
6MP:00053799.7CCKBR, HTR3A, HTR2A, CRH, OXT, SLC6A3
7MP:00036319.6DRD4, NPY, HTR3A, HTR1A, HTR2C, CCKBR
8MP:00053769.6DRD4, NPY, HTR3A, HTR1A, HTR2C, CCKBR
9MP:00053869.6TPH2, COMT, CCKBR, HTR2C, HTR1A, HTR3A

Publications for Anxiety Disorder

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Sources:
50PubMed
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Articles related to Anxiety Disorder:

(show top 50)    (show all 1248)
idTitleAuthorsYear
1
High social support buffers the effects of 5-HTTLPR genotypes within social anxiety disorder. (24407753)
2014
2
Bladder pain syndrome/interstitial cystitis is associated with anxiety disorder. (24038135)
2014
3
Drinking motives in alcohol use disorder patients with and without social anxiety disorder. (23915169)
2014
4
Classifying social anxiety disorder using multivoxel pattern analyses of brain function and structure. (24239689)
2014
5
Haunting self-images? The role of negative self-images in adolescent social anxiety disorder. (23207962)
2013
6
A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder. (23635944)
2013
7
What about the neuroimaging findings in social anxiety disorder? (24032545)
2013
8
A meta-analysis of cognitive therapy for worry in generalized anxiety disorder. (23168445)
2013
9
Remission of generalized anxiety disorder after 6 months of open-label treatment with venlafaxine XR. (24061331)
2013
10
The Diagnostic Utility of Separation Anxiety Disorder Symptoms: An Item Response Theory Analysis. (23963543)
2013
11
Asperger syndrome and anxiety disorders (PAsSA) treatment trial: a study protocol of a pilot, multicentre, single-blind, randomised crossover trial of group cognitive behavioural therapy. (23901031)
2013
12
Neuropsychological functioning in young subjects with generalized anxiety disorder with and without pharmacotherapy. (23796524)
2013
13
A review of the affects of worry and generalized anxiety disorder upon cardiovascular health and coronary heart disease. (23324073)
2013
14
Treating late-life generalized anxiety disorder in primary care: an effectiveness pilot study. (23588228)
2013
15
Clinical and genetic outcome determinants of Internet- and group-based cognitive behavior therapy for social anxiety disorder. (22320999)
2012
16
Comparison of neuropsychological functioning and emotional processing in major depression and social anxiety disorder subjects, and matched healthy controls. (22711880)
2012
17
The course of anxiety disorders other than PTSD in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up study. (23013347)
2012
18
Manualized Cognitive-Behavioral Treatment of Social Anxiety Disorder: A Case Study. (22745596)
2012
19
Generalized anxiety disorder. (22608630)
2012
20
Grey matter abnormalities in social anxiety disorder: a pilot study. (22527992)
2012
21
Predictors of response among patients with panic disorder treated with medications in a naturalistic follow-up: the role of adult separation anxiety. (22134042)
2012
22
Co-morbid anxiety disorders in bipolar disorder and major depression: familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder. (22099954)
2012
23
Changes in risk-taking over the course of an internet-delivered cognitive behavioral therapy treatment for generalized anxiety disorder. (22079215)
2012
24
Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study. (22628125)
2012
25
A multicomponent yoga-based, breath intervention program as an adjunctive treatment in patients suffering from generalized anxiety disorder with or without comorbidities. (22346068)
2012
26
Test-retest reliability of regional electroencephalogram (EEG) and cardiovascular measures in social anxiety disorder (SAD). (22280842)
2012
27
Flight behaviour in humans is intensified by a candidate genetic risk factor for panic disorder: evidence from a translational model of fear and anxiety. (20177409)
2011
28
Prevalence and correlates of generalized anxiety disorder in a national sample of older adults. (21427639)
2011
29
Testing a cognitive model of generalized anxiety disorder in the eating disorders. (21632204)
2011
30
Treatment response for late-life generalized anxiety disorder: moving beyond symptom-based measures. (21964278)
2011
31
Generalized implicit fear associations in generalized anxiety disorder. (20112248)
2010
32
Adult separation anxiety disorder: a disorder comes of age. (20552302)
2010
33
Time to relapse after 6 and 12 months' treatment of generalized anxiety disorder with venlafaxine extended release. (21135327)
2010
34
Generalized anxiety disorder and psychiatric comorbidities such as depression, bipolar disorder, and substance abuse. (19371501)
2009
35
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. (19560279)
2009
36
Overview of generalized anxiety disorder: epidemiology, presentation, and course. (19371500)
2009
37
Escitalopram treatment of generalized anxiety disorder in older adults. (19454633)
2009
38
Anxiety and mood disorder in young males with mitral valve prolapse. (21197339)
2008
39
Health-related quality of life and utilities in primary-care patients with generalized anxiety disorder. (18949580)
2008
40
Separation anxiety disorder in childhood as a risk factor for future mental illness. (18356763)
2008
41
Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. (18559291)
2008
42
Protein-source tryptophan as an efficacious treatment for social anxiety disorder: a pilot study. (18066139)
2007
43
Role of corticotropin releasing factor in anxiety disorders: a translational research perspective. (16870185)
2006
44
Differences in finger length ratio between males with autism, pervasive developmental disorder-not otherwise specified, ADHD, and anxiety disorders. (17109783)
2006
45
Study on anxiety and depressive disorder of inpatients in general hospital]. (12970940)
2003
46
Cognitive-behavioral therapy with a six-year-old boy with separation anxiety disorder: a case study. (11378998)
2001
47
A phase II multicenter dose-finding, efficacy and safety trial of ipsapirone in outpatients with generalized anxiety disorder. (7915845)
1994
48
A prospective study of panic and anxiety in agoraphobia with panic disorder. (1347481)
1992
49
5-HT1A receptor responsivity in anxiety disorders and depression. (1763190)
1991
50
Peripheral-type benzodiazepine receptors in anxiety disorders. (1686517)
1991

Genetic Variations for Anxiety Disorder

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Expression for genes affiliated with Anxiety Disorder

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Anxiety Disorder

Search GEO for disease gene expression data for Anxiety Disorder.

Pathways for genes affiliated with Anxiety Disorder

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Sources:
49PharmGKB, 53Reactome, 37NCBI BioSystems Database, 29KEGG
See all sources

Pathways related to Anxiety Disorder according to GeneCards/GeneDecks:

(show all 16)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.4SLC6A4, SLC6A2
2
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10.4SLC6A3, MAOA
3
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10.4TPH1, TPH2
4
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10.4TPH1, TPH2
5
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10.4TPH1, TPH2
6
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10.3TPH2, TPH1, MAOA
7
Hide members
10.3TPH2, TPH1, MAOA
810.3DRD4, HTR2A, CCKBR
910.2SLC6A3, MAOA, CRH, NPY
1010.2SLC6A3, SLC6A4, SLC6A2, TPH2
11
Hide members
10.2CCKBR, HTR2C, HTR2A, OXT
1210.1HTR1A, HTR3A, HTR2A, MAOA, SLC6A4, TPH1
13
Hide members
10.1SLC6A4, HTR2C, HTR1A, HTR3A, HTR2A, DRD4
14
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9.9CCKBR, HTR2C, HTR1A, HTR2A, NPY, DRD4
15
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9.9COMT, HTR2C, HTR1A, HTR3A, HTR2A, DRD4
16
Hide members
9.8HTR2A, HTR1A, HTR2C, CCKBR, NPY, DRD4

Compounds for genes affiliated with Anxiety Disorder

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Sources:
28IUPHAR, 44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 2BitterDB, 59Tocris Bioscience
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Compounds related to Anxiety Disorder according to GeneCards/GeneDecks:

(show top 50)    (show all 362)
idCompoundScoreTop Affiliating Genes
1mianserin28 44 1112.5HTR2C, HTR1A, HTR3A, HTR2A, MAOA, SLC6A4
2venlafaxine49 44 11 2413.5HTR1A, HTR3A, HTR2A, SLC6A3, SLC6A4, SLC6A2
3mdma4410.5TPH1, MAOA, SLC6A3, SLC6A4, SLC6A2, HTR1A
4sertraline44 28 49 11 2414.5SLC6A4, SLC6A2, SLC6A3, MAOA, HTR1A, HTR3A
5nefazodone44 49 1112.5HTR2C, HTR1A, HTR3A, HTR2A, SLC6A3, SLC6A4
6p-chloroamphetamine4410.5MAOA, HTR1A, SLC6A3, SLC6A4, SLC6A2
75-hydroxytryptophan4410.5HTR3A, HTR2A, HTR1A, TPH1, SLC6A4, CRH
8carbon-114410.5HTR1A, MAOA, SLC6A4, SLC6A3, TSPO
9mhpg4410.5COMT, NPY, DRD4, CRH, MAOA, SLC6A4
10amitriptyline44 49 28 1113.4SLC6A3, SLC6A2, SLC6A4, HTR2A, HTR3A, HTR1A
11fluvoxamine44 49 1112.4HTR1A, HTR3A, HTR2A, MAOA, SLC6A3, SLC6A4
12methamphetamine44 49 1112.4DRD4, MAOA, SLC6A3, SLC6A4, SLC6A2, TPH1
13desipramine44 49 1112.4HTR1A, HTR2A, CRH, MAOA, CNR1, SLC6A3
14yohimbine44 28 2 1113.4HTR1A, HTR2C, CCKBR, HTR3A, NPY, CRH
15citalopram49 44 11 2413.4HTR2C, HTR1A, HTR3A, HTR2A, MAOA, SLC6A3
16homovanillic acid44 2411.4COMT, TPH1, MAOA, SLC6A2, SLC6A4, CRH
17methylphenidate44 49 1112.4SLC6A4, SLC6A3, MAOA, DRD4, SLC6A2, COMT
18mirtazapine49 44 1112.4HTR2A, SLC6A4, HTR3A, TPH2, HTR2C, CRH
19nmda44 2811.4HTR1A, TSPO, SLC6A3, CNR1, MAOA, COMT
20fenfluramine28 44 1112.4NPY, CRH, SLC6A4, TPH1, TPH2, HTR2A
21risperidone28 44 49 59 11 2415.4COMT, HTR2C, HTR1A, HTR3A, HTR2A, DRD4
22m-chlorophenylpiperazine4410.4HTR1A, HTR2C, SLC6A4, HTR2A, HTR3A
235-hydroxyindoleacetic acid44 2411.4TPH1, SLC6A2, SLC6A4, MAOA, HTR3A, CRH
24pramipexole44 49 28 1113.4COMT, HTR1A, HTR2A, DRD4, SLC6A3, HTR2C
25amphetamine44 1111.4MAOA, CNR1, SLC6A3, SLC6A4, SLC6A2, TPH1
26apomorphine44 28 1112.3COMT, HTR2C, HTR1A, HTR2A, DRD4, OXT
27haloperidol44 28 2 49 1114.3CCKBR, HTR1A, HTR3A, HTR2A, NPY, DRD4
283,4-Methylenedioxymethamphetamine1110.3HTR2C, HTR2A, SLC6A3, SLC6A4, SLC6A2
29levodopa44 1111.3COMT, HTR1A, DRD4, MAOA, CNR1, SLC6A3
30clozapine44 28 49 1113.3HTR3A, HTR2A, DRD4, SLC6A3, SLC6A4, HTR1A
31paroxetine44 49 28 1113.3COMT, HTR1A, HTR3A, HTR2A, DRD4, MAOA
32quinpirole44 2811.3SLC6A3, RGS2, HTR2C, CNR1, DRD4, HTR2A
33clomipramine44 49 1112.3SLC6A3, SLC6A4, SLC6A2, TSPO, MAOA, CRH
34maoa4410.3COMT, HTR2C, HTR1A, HTR2A, DRD4, MAOA
35MMDA1110.3MAOA, SLC6A3, SLC6A4, SLC6A2, HTR2A
36olanzapine49 44 28 11 2414.3DRD4, HTR2A, HTR1A, HTR2C, HTR3A, SLC6A3
37acetylcholine44 49 28 11 2414.2HTR1A, HTR3A, NPY, CRH, CNR1, SLC6A3
38imipramine44 49 28 11 2414.2HTR2A, SLC6A2, SLC6A4, SLC6A3, MAOA, HTR3A
39mcpp4410.2HTR2C, HTR1A, HTR3A, HTR2A, SLC6A4
40duloxetine44 49 28 1113.2SLC6A2, SLC6A3, HTR2A, HTR2C, SLC6A4
41cocaine44 1111.2COMT, CCKBR, HTR2C, NPY, DRD4, CRH
42fluoxetine49 44 28 1113.1HTR2A, CRH, OXT, MAOA, CNR1, SLC6A3
43d amphetamine4410.1MAOA, SLC6A3, SLC6A2, TSPO, SLC6A4
44gaba4410.1TPH1, NPY, DRD4, CRH, HTR3A, OXT
45nicotine44 49 28 1113.1TSPO, SLC6A2, SLC6A4, NPY, SLC6A3, TPH1
46glutamate4410.0MAOA, OXT, CRH, DRD4, NPY, HTR2C
475-hydroxytryptamine449.9CRH, MAOA, CNR1, SLC6A3, SLC6A4, SLC6A2
48norepinephrine44 11 2411.9COMT, HTR2C, HTR1A, HTR3A, HTR2A, NPY
49dopamine44 28 11 2412.8TPH1, TSPO, SLC6A2, SLC6A4, SLC6A3, CNR1
50bupropion44 49 11 2412.8COMT, SLC6A2, SLC6A4, SLC6A3, CNR1, NPY

GO Terms for genes affiliated with Anxiety Disorder

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Sources:
16Gene Ontology
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Cellular components related to Anxiety Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058869.7CCKBR, HTR2C, HTR1A, HTR3A, HTR2A, DRD4
2integral to plasma membraneGO:0058879.6SLC6A2, CCKBR, HTR2C, HTR1A, HTR3A, HTR2A

Biological processes related to Anxiety Disorder according to GeneCards/GeneDecks:

(show all 36)
idNameGO IDScoreTop Affiliating Genes
1regulation of serotonin secretionGO:01406210.7CRH, HTR1A
2phospholipase C-activating serotonin receptor signaling pathwayGO:00720810.7HTR2A, HTR2C
3monoamine transportGO:01584410.7SLC6A2, SLC6A4, SLC6A3
4regulation of hormone secretionGO:04688310.7HTR1A, HTR2A
5dopamine catabolic processGO:04242010.7SLC6A3, MAOA, COMT
6regulation of dopamine metabolic processGO:04205310.7HTR1A, DRD4, SLC6A3
7neurotransmitter biosynthetic processGO:04213610.7COMT, MAOA, SLC6A3
8serotonin biosynthetic processGO:04242710.7TPH1, TPH2
9serotonin receptor signaling pathwayGO:00721010.7HTR2C, HTR1A, HTR3A, HTR2A
10agingGO:00756810.7HTR2A, CNR1, TSPO
11aromatic amino acid family metabolic processGO:00907210.7TPH1, TPH2
12response to painGO:04826510.7SLC6A2, CRH, COMT
13behavioral fear responseGO:00166210.7DRD4, HTR1A, HTR2C
14response to immobilization stressGO:03590210.6CRH, TPH1
15feeding behaviorGO:00763110.6CCKBR, HTR2C, NPY, CRH
16positive regulation of phosphatidylinositol biosynthetic processGO:01051310.6HTR2C, HTR2A
17behaviorGO:00761010.6NPY, MAOA, CNR1
18response to etherGO:04547210.6CRH, OXT
19negative regulation of blood pressureGO:04577610.6CRH, OXT, CNR1
20response to cocaineGO:04222010.6HTR3A, OXT, CNR1, SLC6A3
21indolalkylamine biosynthetic processGO:04621910.6TPH1, TPH2
22social behaviorGO:03517610.6SLC6A4, OXT, DRD4
23memoryGO:00761310.6SLC6A4, CNR1, OXT, HTR2A
24circadian rhythmGO:00762310.6TPH2, TPH1, SLC6A4
25sperm ejaculationGO:04271310.5SLC6A4, OXT
26neurotransmitter catabolic processGO:04213510.5MAOA, COMT
27digestionGO:00758610.5NPY, HTR3A, CCKBR
28sleepGO:03043110.5HTR2A, OXT
29response to drugGO:04249310.5COMT, HTR2C, HTR2A, CRH, SLC6A3, SLC6A4
30cellular calcium ion homeostasisGO:00687410.4DRD4, HTR2A, HTR2C
31synaptic transmissionGO:00726810.4SLC6A2, COMT, HTR2C, HTR3A, HTR2A, NPY
32response to ethanolGO:04547110.3CRH, CNR1, SLC6A3
33regulation of behaviorGO:05079510.3HTR1A, HTR2A
34response to stressGO:00695010.3TPH2, CNR1, HTR2A
35female pregnancyGO:00756510.3COMT, CRH, OXT
36synaptic transmission, dopaminergicGO:00196310.0DRD4, CRH

Molecular functions related to Anxiety Disorder according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1monoamine transmembrane transporter activityGO:00850410.4SLC6A3, SLC6A4, SLC6A2
2serotonin receptor activityGO:00499310.4HTR2C, HTR1A, HTR3A, HTR2A
3dopamine bindingGO:03524010.3SLC6A3, DRD4
4serotonin bindingGO:05137810.3HTR2A, HTR3A, HTR2C
5drug bindingGO:00814410.3SLC6A3, CNR1, DRD4, HTR2A, HTR2C
61-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine bindingGO:07188610.3HTR2C, HTR2A
7tryptophan 5-monooxygenase activityGO:00451010.1TPH1, TPH2

Products for genes affiliated with Anxiety Disorder

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Sources for Anxiety Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet