MCID: ART016
MIFTS: 62

Aortic Aneurysm malady

Summaries for Aortic Aneurysm

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33MedlinePlus, 3CDC, 63Wikipedia, 32MalaCards
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MedlinePlus:33 An aneurysm is a bulge or "ballooning" in the wall of an artery. arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. if an aneurysm grows large, it can burst and cause dangerous bleeding or even death. most aneurysms are in the aorta, the main artery that runs from the heart through the chest and abdomen. there are two types of aortic aneurysm: thoracic aortic aneurysms - these occur in the part of the aorta running through the chest abdominal aortic aneurysms - these occur in the part of the aorta running through the abdomen most aneurysms are found during tests done for other reasons. some people are at high risk for aneurysms. it is important for them to get screening, because aneurysms can develop and become large before causing any symptoms screening is recommended for people between the ages of 65 and 75 if they have a family history, or if they are men who have smoked. doctors use imaging tests to find aneurysms. medicines and surgery are the two main treatments. nih: national heart, lung, and blood institute

MalaCards: Aortic Aneurysm is related to abdominal aortic aneurysm and thoracic aortic aneurysm. An important gene associated with Aortic Aneurysm is ACTA2 (actin, alpha 2, smooth muscle, aorta), and among its related pathways are Integrin Pathway and Rho Family GTPases. The drug trimethaphan camsylate and the compounds serine and vegf have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and lung, and related mouse phenotypes are homeostasis/metabolism and immune system.

CDC:3 An aortic aneurysm is a balloon-like bulge in the aorta, the large artery that carries blood from the heart through the chest and torso.

Wikipedia:63 An aortic aneurysm is a general term for an enlargement (dilation) of the aorta to greater than 1.5... more...

Aliases & Classifications for Aortic Aneurysm

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8Disease Ontology, 10DISEASES, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH
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Aliases & Descriptions:

aortic aneurysm 8 10 33 60


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Disease Ontology8 DOID:3627
NCIt39 C26697
MeSH34 D001014

Related Diseases for Aortic Aneurysm

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17GeneCards, 18GeneDecks
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Diseases related to Aortic Aneurysm via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 308)
idRelated DiseaseScoreTop Affiliating Genes
1abdominal aortic aneurysm32.3MMP9
2thoracic aortic aneurysm32.0TGFBR2, ELN, MMP1, MMP2, MYH11, FBN1
3dissecting aortic aneurysm31.8ELN
4aneurysm disease31.5TGFBR2, ELN, ELANE, MMP9, MMP12, MMP8
5aortic disease31.4FBN1, ELN
6marfan syndrome31.1COL3A1, FBN1, ELN, TGFBR2, TGFBR1
7hypertension30.9MMP9
8atherosclerosis30.7FBN1, MYH11, MMP2, MMP8, MMP12, MMP1
9loeys-dietz syndrome30.7COL3A1, FBN1, ACTA2, TGFBR2, TGFBR1
10coronary artery disease30.6COL3A1, FBN1, MMP12, MMP9
11pancreatitis30.6ELANE
12vascular disease30.5MMP9, ELANE, ELN, TGFBR1
13ehlers-danlos syndrome30.5COL3A1, FBN1, ELN
14intracranial aneurysm30.5ELN, ELANE, COL3A1
15pneumonia30.5ELANE, MMP12, MMP8
16aortic valve stenosis30.4ELN
17myocardial infarction30.4COL3A1
18arteriosclerosis30.4ELN
19thoracic aortic aneurysms and aortic dissections30.3TGFBR1, TGFBR2, ACTA2, MYH11
20ehlers-danlos syndrome type iv30.3COL3A1, ELN
21lung cancer30.3MMP2, MMP1, MMP9, TGFBR2
22osteoarthritis30.2MMP2, MMP8, MMP12, MMP1, MMP9
23cutis laxa30.2FBN1, ELANE, ELN
24peritonitis30.2COL3A1, MMP8
25acute myocardial infarction30.2MMP9, MMP8
26colon cancer30.2MMP2, MMP9, SMAD3, TGFBR2, TGFBR1
27diabetes mellitus30.2MMP9
28gallbladder cancer30.2TGFBR2
29supravalvular aortic stenosis30.2FBN1, ELN
30connective tissue disease30.2FBN1
31colorectal cancer30.2TGFBR2, MMP9, MMP1, MMP2
32hepatocellular carcinoma29.9FBN1, MMP2, MMP12, MMP9, SMAD3, ELANE
33squamous cell carcinoma29.9MMP2, MMP12, MMP1, MMP9, SMAD3, TGFBR2
34rheumatoid arthritis29.9MMP2, MMP8, MMP12, MMP1, MMP9, ELANE
35pulmonary emphysema29.9MMP8, MMP12, MMP1, MMP9, ELANE, ELN
36arthritis29.9FBN1, MMP2, MMP8, MMP12, MMP1, MMP9
37exfoliation syndrome29.9FBN1, MMP1, ELN
38bladder carcinoma29.9MMP2, MMP12, MMP9, TGFBR1
39pneumothorax29.9COL3A1
40mitral valve prolapse29.9FBN1
41alpha 1-antitrypsin deficiency29.9ELANE
42leukemia29.9MYH11, SMAD3, TGFBR1
43pseudoxanthoma elasticum29.9FBN1, ELN
44transitional cell carcinoma29.9TGFBR1, TGFBR2, MMP9
45acute pancreatitis29.9ELANE
46ruptured aortic aneurysm11.4
47ruptured abdominal aortic aneurysm11.3
48ruptured thoracic aortic aneurysm10.9
49ischemia10.8
50familial thoracic aortic aneurysm and dissection10.7

Graphical network of the top 20 diseases related to Aortic Aneurysm:



Diseases related to aortic aneurysm

Clinical Features for Aortic Aneurysm

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Drugs & Therapeutics for Aortic Aneurysm

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Aortic Aneurysm

Drug clinical trials:

Search ClinicalTrials for Aortic Aneurysm

Search NIH Clinical Center for Aortic Aneurysm

Search CenterWatch for Aortic Aneurysm

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Aortic Aneurysm

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Anatomical Context for Aortic Aneurysm

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32MalaCards
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MalaCards organs/tissues related to Aortic Aneurysm:

32
Kidney, Heart, Lung, Spinal cord, Testes, Smooth muscle, Colon, Endothelial, Monocytes, T cells, Bone, Thyroid, Liver, Small intestine, Brain, Myeloid, Whole blood, Trachea, Pituitary

Animal Models for Aortic Aneurysm or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Aortic Aneurysm:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537611.7COL3A1, FBN1, MYLK, MYH11, MMP2, MMP12
2MP:000538711.4FBN1, MYLK, MMP2, MMP8, MMP12, MMP9
3MP:001076811.4MYH11, MYLK, FBN1, COL3A1, MMP2, MMP9
4MP:000536911.4COL3A1, FBN1, MYLK, MYH11, MMP2, MMP9
5MP:000538511.4TGFBR1, FBN1, MYLK, MYH11, MMP12, ACTA2
6MP:000200611.2MMP2, MMP8, MMP9, SMAD3, ELANE, TGFBR2
7MP:000538811.2COL3A1, MMP2, MMP9, ELN, TGFBR2, TGFBR1
8MP:001077111.2TGFBR1, SMAD3, MMP9, MMP12, MYH11, FBN1
9MP:000539010.6FBN1, MYLK, SMAD3, TGFBR1

Publications for Aortic Aneurysm

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50PubMed
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Articles related to Aortic Aneurysm:

(show top 50)    (show all 2866)
idTitleAuthorsYear
1
Changes in the management of infrarenal abdominal aortic aneurysm disease in Sweden. (23334950)
2013
2
Hybrid treatment for thoracic aortic aneurysm combined with aberrant right subclavian artery. (23407812)
2013
3
Multidetector computed tomography findings of abdominal aortic aneurysm and its complications: a pictorial review. (23609615)
2013
4
Renal function 5 years after open and endovascular aortic aneurysm repair from a randomized trial. (24037566)
2013
5
Hybrid treatment option for aortic arch anomalies and descending thoracic aortic aneurysm. (23796094)
2013
6
Nonoperative approach for ruptured abdominal aortic aneurysm: still an option in the 21st century? (23870225)
2013
7
Hybrid endovascular treatment of an aortic root and thoracoabdominal aneurysm in a high-risk patient with Marfan syndrome. (23567801)
2013
8
Comparison of outcomes for open abdominal aortic aneurysm repair and endovascular repair in patients with chronic renal insufficiency. (24022432)
2013
9
Effect of ethnicity and insurance type on the outcome of open thoracic aortic aneurysm repair. (23540667)
2013
10
Clinical implications of non-contrast-enhanced computed tomography for follow-up after endovascular abdominal aortic aneurysm repair. (23711975)
2013
11
Measuring and modeling patient-specific distributions of material properties in abdominal aortic aneurysm wall. (22955570)
2013
12
A case of severe aortic valve regurgitation caused by an ascending aortic aneurysm in a young patient with autosomal dominant polycystic kidney disease and normal renal function. (22396705)
2012
13
Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study. (22844527)
2012
14
Gene-environment interaction for the HIF1-A 1772C>T polymorphisms and cigarette smoking increase susceptibility to abdominal aortic aneurysm]. (23421024)
2012
15
Wireless Power Transmission for Powering Medical Implants Situated in an Abdominal Aortic Aneurysm. (22962165)
2012
16
Regarding "Annual rupture risk of abdominal aortic aneurysm enlargement without detectable endoleak after endovascular abdominal repair". (22749275)
2012
17
Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm. (21899841)
2011
18
A meta-analysis of randomized and risk-adjusted observational studies of endovascular versus open repair for ruptured abdominal aortic aneurysm. (22262115)
2011
19
Endovascular thoracic aortic repair and risk of spinal cord ischemia: the role of previous or concomitant treatment for aortic aneurysm. (20354486)
2010
20
Smooth muscle phenotypic modulation is an early event in aortic aneurysms. (19931668)
2009
21
Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK. (19729613)
2009
22
Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients. (18600213)
2008
23
Extending hybrid approach to residual Stanford type A dissecting aortic aneurysm. (18658166)
2008
24
Matrix metalloproteinase and tissue inhibitor expression in atherosclerotic and nonatherosclerotic thoracic aortic aneurysms. (17198804)
2007
25
Two-stage successful surgery in an aortic coarctation case operated initially for ascending aortic aneurysm. (18065348)
2007
26
Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds. (17182923)
2006
27
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. (16864727)
2006
28
Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease. (16520158)
2006
29
Reoperation for ascending aortic aneurysm, coronary ostial aneurysm and patent Cabrol trick after bentall operation for aortitis syndrome. (15988114)
2005
30
Ruptured abdominal aortic aneurysm: endovascular treatment. (15759206)
2005
31
Descending thoracic aortic aneurysm repair: 12-year experience using distal aortic perfusion and cerebrospinal fluid drainage. (16181856)
2005
32
Ruptured abdominal aortic aneurysm with aorto-caval fistula. (15337896)
2004
33
Accuracy of abdominal examination in the diagnosis of non-ruptured abdominal aortic aneurysm. (15041011)
2004
34
Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. (15238617)
2004
35
Ruptured right aortic arch aneurysm. (15585709)
2004
36
Matrix metalloproteinase 9 activity in patients before and after endovascular or surgical repair of abdominal aortic aneurysms. (15765912)
2004
37
Combined minimally invasive procedure for descending thoracic aortic aneurysm with left main coronary artery disease. (14735036)
2003
38
Caval and ureteral obstruction secondary to an inflammatory abdominal aortic aneurysm. (14681651)
2003
39
Genetic analysis on HLA loci in Japanese patients with abdominal aortic aneurysm. (12917841)
2003
40
Ruptured abdominal aortic aneurysm complicated by horseshoe kidney and renal cell carcinoma. (12475681)
2002
41
Observations on the Heart - Aneurysm of the False Channel of Descending Thoracic Aorta Years After Operative Excision of the Initiating Aortic Dissection Tear in Ascending Aorta. (11416544)
2000
42
Patterns of expression of fibrinolytic genes and matrix metalloproteinase-9 in dissecting aortic aneurysms. (9502412)
1998
43
Liquefaction of thrombus in thoracic aortic aneurysm: MR findings. (7785614)
1995
44
Loss of a right radial arterial pressure tracing during thoracic aortic aneurysm repair. (7579115)
1995
45
Necrotising pancreatitis due to a ruptured abdominal aortic aneurysm. (8088408)
1994
46
Aortoesophageal fistula secondary to thoracic aortic aneurysm repair. (8282742)
1993
47
Ruptured abdominal aortic aneurysm. A twelve-year experience. (7142794)
1982
48
Disseminated intravascular coagulation in dissecting aortic aneurysm. A case report. (7290724)
1981
49
Cerebral disseminated coagulation. An encephalitis-like syndrome in a boy with dissecting aortic aneurysm. (6164760)
1981
50
Dissecting aortic aneurysm. (13629413)
1959

Genetic Variations for Aortic Aneurysm

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Expression for genes affiliated with Aortic Aneurysm

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Aortic Aneurysm

Search GEO for disease gene expression data for Aortic Aneurysm.

Pathways for genes affiliated with Aortic Aneurysm

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51QIAGEN, 53Reactome, 12EMD Millipore, 29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 4Cell Signaling Technology, 59Tocris Bioscience
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Pathways related to Aortic Aneurysm according to GeneCards/GeneDecks:

(show all 40)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.4COL3A1, FBN1, MYLK, MYH11, MMP2, MMP8
2
Hide members
11.3COL3A1, FBN1, MYLK, MYH11, ACTA2, ELN
3
Hide members
11.2MMP2, MMP8, MMP12, MMP1, MMP9, ACTA2
4
Hide members
11.1COL3A1, FBN1, MMP2, MMP8, MMP12, MMP1
5
Cell adhesion ECM remodeling
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11.1ELN, COL3A1, MMP2, MMP8, MMP12, MMP1
611.1MMP2, MMP1, MMP9, SMAD3, TGFBR2, TGFBR1
7
Hide members
11.0TGFBR1, TGFBR2, ACTA2, MYH11, MYLK
8
Hide members
11.0TGFBR1, ACTA2, MMP9, MMP2, MYLK
9
Hide members
11.0MMP2, MMP8, MMP12, MMP1, MMP9
10
Hide members
10.9COL3A1, FBN1, ACTA2, TGFBR1
11
Transcription Androgen Receptor nuclear signaling
Hide members
10.9MMP2, SMAD3, TGFBR2, TGFBR1
1210.9MMP12, MMP1, TGFBR2, TGFBR1
13
Hide members
10.9COL3A1, MMP2, MMP8, MMP12
14
Cell adhesion Cell-matrix glycoconjugates
Hide members
10.9MMP1, MMP9, ELANE, ELN
1510.8ACTA2, TGFBR2, TGFBR1
16
Hide members
10.8TGFBR1, TGFBR2, ELN
1710.8SMAD3, TGFBR2, TGFBR1
1810.8SMAD3, TGFBR2, TGFBR1
19
Hide members
10.8TGFBR1, TGFBR2, SMAD3
2010.8TGFBR1, TGFBR2, SMAD3
21
Hide members
10.8TGFBR1, TGFBR2, SMAD3
22
Development TGF-beta receptor signaling
Hide members
10.8TGFBR1, TGFBR2, SMAD3
2310.8TGFBR1, TGFBR2, SMAD3
24
Hide members
10.8SMAD3, TGFBR2, TGFBR1
2510.8TGFBR1, TGFBR2, SMAD3
26
Cytokine production by Th17 cells in CF (Mouse model)
10.8SMAD3, TGFBR2, TGFBR1
27
Hide members
10.8MYLK, MYH11, ACTA2
2810.8MMP2, MMP9, TGFBR1
2910.8MMP2, MMP1, MMP9
3010.8MMP2, MMP9, SMAD3
3110.8MMP2, MMP9, ELANE
32
Hide members
10.7TGFBR1, TGFBR2
33
Hide members
10.7TGFBR1, TGFBR2
3410.7TGFBR1, TGFBR2
35
Hide members
10.7TGFBR1, TGFBR2
36
Hide members
10.7TGFBR2, TGFBR1
37
Hide members
10.7TGFBR2, TGFBR1
38
Hide members
10.7ELN, ELANE
39
Hide members
10.7ELANE, MMP9
4010.6SMAD3

Compounds for genes affiliated with Aortic Aneurysm

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Sources:
44Novoseek, 24HMDB, 28IUPHAR, 59Tocris Bioscience, 2BitterDB, 11DrugBank
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Compounds related to Aortic Aneurysm according to GeneCards/GeneDecks:

(show top 50)    (show all 103)
idCompoundScoreTop Affiliating Genes
1serine4411.9MMP1, ELN, TGFBR1, MMP9, MMP12, MMP8
2vegf4411.9SMAD3, MMP9, ELN, TGFBR2, MMP1, MMP12
3retinoic acid44 2412.9TGFBR1, TGFBR2, ELN, MYH11, ELANE, MMP1
4alanine4411.7TGFBR1, FBN1, MYLK, TGFBR2, ELN, SMAD3
5tgf beta14411.7TGFBR1, MMP9, ELN, SMAD3, MMP1, MMP2
6cysteine4411.5MMP9, ELANE, ELN, TGFBR2, MMP8, FBN1
7genistein44 28 59 2 11 2416.5MMP1, MMP9, MMP2, MMP8, MMP12, ELN
8batimastat44 59 1113.5MMP2, ELANE, MMP9, MMP1, MMP12, MMP8
9progesterone44 59 28 11 2415.5MMP2, MYH11, FBN1, TGFBR1, MMP1, MMP8
10hyaluronic acid44 2412.5FBN1, MMP2, MMP1, MMP9, ELANE, ELN
11matrigel4411.4SMAD3, TGFBR1, MMP9, MMP12, MMP2, MMP1
12ribonucleic acid4411.4COL3A1, MMP1, MMP9, TGFBR2, TGFBR1, MMP2
13n acetylcysteine4411.4ELN, MMP9, MMP12, SMAD3, MMP2, MMP1
14uk 3833675911.4MMP1, MMP12, MMP9, MMP2, MMP8
15gi 254023x5911.4MMP8, MMP2, MMP12, MMP1, MMP9
16gm 60015911.4MMP2, MMP8, MMP12, MMP9, MMP1
17ly2940024411.4SMAD3, MYH11, TGFBR1, MMP2, TGFBR2, MMP9
18hydroxamate4411.4MMP9, MMP1, MMP12, MMP2, MMP8
19marimastat44 59 1113.4MMP1, MMP2, MMP8, MMP12, MMP9
20hydroxyproline44 11 2413.4FBN1, MMP2, MMP1, MMP9, ELN
21paraffin4411.4TGFBR1, MYH11, MMP2, MMP1, MMP9, ELN
22tetracycline44 1112.3TGFBR2, MMP9, MMP1, MMP8, MMP2
23cytochalasin d44 5912.3MMP1, MMP2, MMP9, ACTA2, MYLK
24ilomastat4411.3MMP2, ELANE, MMP9, MMP1
25cilomilast4411.3ELANE, MMP9, MMP1, MMP2
26lactate4411.3ELN, ELANE, MMP2, MMP1, MMP8, MMP9
27cyclosporin a44 28 5913.2TGFBR2, MMP8, ELANE, COL3A1, MMP1
28zinc44 2412.2MMP2, MMP12, MMP1, SMAD3, MMP8, TGFBR2
29doxycycline44 1112.2ELANE, MMP1, MMP8
30cgs-27023a4411.2MMP1, MMP9, MMP2
31vgvapg4411.2MMP1, MMP2, ELN
32nitric oxide44 11 2413.2TGFBR2, SMAD3, MMP12, MMP8, TGFBR1, MYLK
33desmosine4411.1FBN1, ELANE, ELN
34prinomastat4411.1MMP2, MMP1, MMP9
35(4-aminophenyl)mercuric acetate4411.1ELANE, MMP8
36vitamin a44 11 2413.1MMP1, MMP9, ELANE, MMP2
37gelfoam4411.1MMP9, ELN, MMP2
38latanoprost44 1112.1MMP9, MMP2, MMP1
39hematoxylin4411.0ELN, MMP1, MYH11
40bleomycin44 1112.0SMAD3, MMP9, TGFBR2, ELN
41estrogen4411.0ELN
42aprotinin44 1112.0ELANE, MMP2, MMP1, MMP9
43glutamate4410.9FBN1
44cycloheximide4410.9ELN
45cacl24410.9FBN1, MMP8, ELN
46pge24410.9MMP2, MMP9
47thermolysin4410.9ELN, ELANE
48glycosaminoglycan4410.8MMP1, MMP8, MMP9, ELN
49isodesmosine4410.7ELANE, ELN
50sodium dodecylsulfate4410.5ELN, ELANE, FBN1

GO Terms for genes affiliated with Aortic Aneurysm

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16Gene Ontology
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Cellular components related to Aortic Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557611.3COL3A1, FBN1, MMP2, MMP8, MMP12, MMP1
2proteinaceous extracellular matrixGO:00557811.2ELN, FBN1, MMP2, MMP8, MMP12, MMP1
3transforming growth factor beta receptor homodimeric complexGO:07002210.7TGFBR1, TGFBR2
4receptor complexGO:04323510.7SMAD3, TGFBR2, TGFBR1
5smooth muscle contractile fiberGO:03048510.4ACTA2, MYH11

Biological processes related to Aortic Aneurysm according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1extracellular matrix organizationGO:03019811.6COL3A1, FBN1, MMP2, MMP8, MMP12, MMP1
2collagen catabolic processGO:03057411.4ELANE, COL3A1, MMP2, MMP8, MMP12, MMP1
3extracellular matrix disassemblyGO:02261711.4COL3A1, MMP2, MMP8, MMP12, MMP1, MMP9
4proteolysisGO:00650811.3MMP2, MMP8, MMP12, MMP1, MMP9, ELANE
5wound healingGO:04206011.1COL3A1, SMAD3, TGFBR2, TGFBR1
6transforming growth factor beta receptor signaling pathwayGO:00717911.0COL3A1, SMAD3, TGFBR2, TGFBR1
7skeletal system developmentGO:00150111.0TGFBR1, MMP9, FBN1, COL3A1
8embryonic cranial skeleton morphogenesisGO:04870111.0TGFBR1, TGFBR2, SMAD3
9heart developmentGO:00750710.9TGFBR1, TGFBR2, FBN1, COL3A1
10embryo implantationGO:00756610.9MMP2, MMP9, TGFBR2
11response to cholesterolGO:07072310.7TGFBR1, TGFBR2
12pathway-restricted SMAD protein phosphorylationGO:06038910.7TGFBR1, TGFBR2
13negative regulation of transforming growth factor beta receptor signaling pathwayGO:03051210.7SMAD3, TGFBR2, TGFBR1
14muscle contractionGO:00693610.5ACTA2, MYH11, MYLK

Molecular functions related to Aortic Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1metalloendopeptidase activityGO:00422211.1MMP9, MMP1, MMP12, MMP8, MMP2
2SMAD bindingGO:04633210.8TGFBR1, TGFBR2, COL3A1
3extracellular matrix structural constituentGO:00520110.8COL3A1, FBN1, ELN
4transforming growth factor beta-activated receptor activityGO:00502410.7TGFBR1, TGFBR2
5transmembrane receptor protein serine/threonine kinase activityGO:00467510.6TGFBR1, TGFBR2
6transforming growth factor beta bindingGO:05043110.4TGFBR1, TGFBR2

Products for genes affiliated with Aortic Aneurysm

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  • Antibodies
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Sources for Aortic Aneurysm

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet