MCID: ART031
MIFTS: 53

Aortic Coarctation malady

Categories: Rare diseases, Cardiovascular diseases, Fetal diseases

Aliases & Classifications for Aortic Coarctation

About this section
Sources:
45NIH Rare Diseases, 51Orphanet, 24GTR, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Aortic Coarctation:

Name: Aortic Coarctation 45
Aorta Coarctation 51 24
 
Coarctation of the Aorta 45

Characteristics:

Orphanet epidemiological data:

51
aorta coarctation:
Prevalence: 1-5/10000 (Europe),6-9/10000 (Austria),1-5/10000 (Belgium),1-5/10000 (Croatia),1-5/10000 (Denmark),1-5/10000 (France),1-5/10000 (Germany),1-5/10000 (Hungary),1-5/10000 (Ireland),1-5/10000 (Italy),1-5/10000 (Malta),1-5/10000 (Netherlands),1-5/10000 (Norway),1-9/100000 (Poland),1-9/100000 (Portugal),1-5/10000 (Spain),1-5/10000 (Switzerland),1-5/10000 (United Kingdom),1-5/10000 (Ukraine); Age of onset: Infancy,Neonatal

Classifications:



External Ids:

Orphanet51 1457
UMLS via Orphanet66 C0003492
ICD10 via Orphanet28 Q25.1
MESH via Orphanet37 C531623, D001017
ICD1027 Q25.1

Summaries for Aortic Coarctation

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MalaCards based summary: Aortic Coarctation, also known as aorta coarctation, is related to heart disease and hemangioma, and has symptoms including hypoplastic left heartand coarctation of aorta. An important gene associated with Aortic Coarctation is ACE (Angiotensin I Converting Enzyme), and among its related pathways are Physiological and Pathological Hypertrophy of the Heart and AGE-RAGE signaling pathway in diabetic complications. Affiliated tissues include heart, prostate and breast, and related mouse phenotypes are adipose tissue and renal/urinary system.

Related Diseases for Aortic Coarctation

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Diseases related to Aortic Coarctation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 156)
idRelated DiseaseScoreTop Affiliating Genes
1heart disease30.2ACE, EDN1, NOS3
2hemangioma29.5ACE, FBN1, NOTCH1
3coronary artery disease29.2ACE, ADRB1, AGTR1, EDN1, NOS3
4left ventricular outflow tract obstruction11.6
5atypical coarctation of aorta11.2
6phace syndrome10.7
7pulmonary blastoma10.7ACE, NOS3
8aneurysm10.6
9progeria variant syndrome ruvalcaba type10.6EDN1, NOS3
10oral squamous cell carcinoma10.6ACE, NOS3
11hypochromic microcytic anemia with iron overload10.6ACE, CYP11B2
12coronary thrombosis10.6EDN1, NOS3
13diabetic autonomic neuropathy10.5ACE, FBN1
14lethal congenital contractural syndrome 210.5EDN1, NOS3
15thrombocytopenia10.5EDN1, NOS3
16rheumatic fever10.5EDN1, NOS3
17pediatric multiple sclerosis10.5ACE, AGT
18multicentric reticulohistiocytosis10.5ACE, EDN1
19paraphilia disorder10.5ACE, NOS3
20idiopathic hypersomnia10.5ACE, EDN1
21acute sphenoidal sinusitis10.4EDN1, NOS3
22periampullary adenoma10.4ACE, EDN1, NOS3
23obstructive sleep apnea10.4ACE, EDN1, NOS3
24glandular cystitis10.3ACE, AGTR1, NOS3
25mitochondrial metabolism disease10.3ACE, EDN1, NOS3
26ischemic optic neuropathy10.3ACE, AGTR1, NOS3
27temporal lobe epilepsy10.3ACE, EDN1, FBN1
28parametritis10.3ACE, AGT
29twin-to-twin transfusion syndrome10.3ACE, EDN1, NOS3
30ventricular septal defect10.3
31aortic aneurysm10.3
32citrullinemia, adult-onset type ii10.3ACE, AGTR1, NOS3
33cerebellar angioblastoma10.3ACE, EDN1, FBN1
34lymph node adenoid cystic carcinoma10.3EDN1, FBN1
35patent ductus arteriosus10.2
36cerebritis10.2
37coxa vara, congenital10.2ACE, AGTR1, EDN1
38endogenous depression10.2ACE, AGTR1, EDN1
39hypoaldosteronism, congenital, due to cmo ii deficiency10.2AGT, CYP11B2
40acrodermatitis10.2EDN1, NOS3
41stroke, ischemic10.2ACE, AGTR1, NOS3
42heart aneurysm10.2AGTR1, EDN1
43thrombotic thrombocytopenic purpura10.2AGTR1, EDN1, NOS3
44multilocular clear cell renal cell carcinoma10.2ACE, AGTR1, CYP11B2
45specific bursitis often of occupational origin10.1ACE, AGT
46familial hyperthyroidism due to mutations in tsh receptor10.1AGTR1, CYP11B2, GRK4
47idiopathic membranous glomerulonephritis10.1ACE, AGT, AGTR1
48adult extraosseous chondrosarcoma10.1ADRB1, ADRB2
49adult acute lymphocytic leukemia10.1ACE, ADRB1, EDN1
50fibrosing mediastinitis10.1ACE, AGT, AGTR1

Graphical network of the top 20 diseases related to Aortic Coarctation:



Diseases related to aortic coarctation

Symptoms for Aortic Coarctation

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HPO human phenotypes related to Aortic Coarctation:

id Description Frequency HPO Source Accession
1 hypoplastic left heart HP:0004383
2 coarctation of aorta HP:0001680

Drugs & Therapeutics for Aortic Coarctation

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Drugs for Aortic Coarctation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41804
2Anticholesteremic AgentsPhase 41732
3Contraceptives, OralPhase 43734
4Hypolipidemic AgentsPhase 42228
5AntimetabolitesPhase 49454
6Atorvastatin CalciumPhase 4714134523-03-8
7Calcium, DietaryPhase 44678
8
Nitroglycerinapproved, investigationalPhase 213955-63-04510
Synonyms:
1,2,3-Propanetrioltrinitrate
1,2,3-Propanetriyl nitrate
100292-13-5
105469-31-6
55-63-0
80066-48-4
8013-23-8
9010-02-0
AC1L1IBV
Adesitrin
Aldonitrin
Angibid
Angiolingual
Angiplex
Anglix
Angonist
Angorin
Anogesic
Aquo-Trimitrosan
BIDD:GT0142
BRN 1802063
Blasting gelatin
Blasting oil
Buccal
Buccard
C07455
C3H5N3O9
CCRIS 4089
CHEBI:28787
CHEMBL730
CID4510
CPD-143
Cardabid
Cardamist
Cardinit
Cardiodisco
Cellegesic
Chitamite
Colenitral
Cordipatch
Corditrine
Coro-Nitro
D00515
D005996
DB00727
Dauxona
Deponit
Deponit 5
Deponit TTS 10
Deponit TTS 5
Deponit-5
Diafusor
Discotrine
Dynamite
EINECS 200-240-8
Epinitril
GTN
GTN-Pohl
Gepan Nitroglicerin
Gilucor nitro
Gilustenon
Glonoin
Glycerin trinitrate
Glycerine trinitrate
Glycerintrinitrate
Glycerol trinitrate
Glycerol, nitric acid triester
Glyceroli trinitratis
Glyceroltrinitraat
Glyceroltrinitrat
Glyceryl
Glyceryl nitrate
Glyceryl trinitrate
Glycerylnitrat
Glytrin
HMS2094M15
HSDB 30
Herwicard
Herzer
IMX-150
Klavikordal
LS-7741
Lenitral
Lentonitrina
MED-2002
MQX-503
Mi-Trates
Millisrol
Minitram
Minitran
Minitran (TN)
Minitro
Mionitrat
Myocon
Myoglycerin
Myovin
NG
NITRO IV
NK-843
NTG
Natispray
Neos nitro OPT
Niglin
Niglycon
Niong
Niong Retard
Nirmin
Nit-Ret
Nitora
Nitradisc
Nitradisc Pad
Nitradisc TTS
Nitrangin
Nitrek
Nitriderm
Nitriderm TTS
Nitrine-TDC
Nitro Bid
Nitro Dur
Nitro Dur TTS
Nitro Mack Retard
Nitro Retard
Nitro Rorer
Nitro-Bid
Nitro-Dur 10
Nitro-Dur 5
Nitro-Gesanit Retard
Nitro-M-Bid
Nitro-Mack Retard
Nitro-Par
Nitro-Pflaster
Nitro-Span
Nitro-Time
Nitro-bid
Nitro-bid (TN)
Nitro-dur
Nitro-dur (TN)
Nitro-lent
NitroBid
NitroCor
NitroDur
NitroMist
NitroQuick
 
NitroQuik
Nitroard
Nitrobaat
Nitrobid Oint
Nitrobukal
Nitrocap
NitrocapT.D
NitrocapT.D.
Nitrocard
Nitrocerin
Nitrocine
Nitrocine 5
Nitroclyn
Nitrocontin
Nitrocontin Continus
Nitrocot
Nitroderm
Nitroderm TTS
Nitroderm TTS Ext
Nitroderm TTS-5
Nitrodisc
Nitrodyl
Nitrodyl TTS
Nitrogard
Nitrogard-SR
Nitroglicerina
Nitrogliceryna
Nitroglin
Nitroglycerin
Nitroglycerin (NG)
Nitroglycerin ER
Nitroglycerin Lingual
Nitroglycerin Transdermal Delivery System
Nitroglycerin Transdermal System
Nitroglycerin ointment
Nitroglycerin-ACC
Nitroglycerine
Nitroglycerol
Nitroglyn
Nitroject
Nitrol Ointment
Nitrolan
Nitroletten
Nitrolin
Nitrolingual
Nitrolingual Pumpspray
Nitrolingual Spray
Nitrolowe
Nitromack Retard
Nitromed
Nitromel
Nitromex
Nitromint
Nitromint Aerosol
Nitromint Retard
Nitromist
Nitromist (TN)
Nitronal Aqueous
Nitronet
Nitrong
Nitrong Retard
Nitrong parenteral
Nitrong-SR
Nitropatch
Nitropen
Nitropercuten
Nitroperlinit
Nitroplast
Nitroprol
Nitropront
Nitroprontan
Nitrorectal
Nitroretard
Nitrorex
Nitrospan
Nitrostabilin
Nitrostat
Nitrovis
Nitrozell retard
Nysconitrine
Percutol
Percutol Oint
Percutol Oint.
Perganit
Perglottal
Perlinganit
Plastranit
Polnitrin
Propane-1,2,3-triyl trinitrate
RCRA waste no. P081
Ratiopharm
Rectiv
Rectogesic
SDM No. 17
SK-106N
SK-866
SK-878
Soup
Spirit of glonoin
Susadrin
Suscard
Sustac
Sustak
Sustonit
TNG
Temponitrin
Top-Nitro
Transderm Nitro
Transderm nitro
Transderm-N TTS
Transderm-Nitro TTS
Transderm-nitro
Transderm-nitro (TN)
Transiderm-nitro
Tridil
Tridil sublin
Trinalgon
Trinipatch
Triniplas
Trinitrate, Glyceryl
Trinitrin
Trinitrin Tablets
Trinitrina Erba
Trinitrine
Trinitroglycerin
Trinitroglycerol
Trinitrol
Trinitrolong
Trinitron
Trinitrosan
Turicard
UN0143
UN0144
UN1204
UN3064
UN3319
UNII-G59M7S0WS3
Vascana
Vasoglyn
Vasolator
Vernies
Willong
c0061
nitroglycerin
9
Nitric OxideapprovedPhase 256410102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
10
NitroprussideapprovedPhase 25815078-28-111963622
Synonyms:
13755-38-9 (di-hydrochloride salt, diH20)
14402-89-2 (di-hydrochloride salt)
15078-28-1
C07269
CHEMBL74115
CID11953891
Disodium nitroprusside dihydrate
LS-187044
Nipride
Nitroferricyanide
 
Nitropress
Nitroprusside
Pentacyanidonitrosylferrate(2-)
Sodium Nitroprusside
Sodium nitroferricyanide dihydrate
Sodium nitroprusside
Sodium nitroprusside dihydrate
Sodium nitroprusside extra pure
UNII-169D1260KM
[Fe(CN)5(NO)](2-)
nitroferricyanide
11
SevofluraneapprovedPhase 242928523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
12Nitric Oxide DonorsPhase 2100
13Platelet Aggregation InhibitorsPhase 21935
14Vasodilator AgentsPhase 22926
15Central Nervous System DepressantsPhase 210016
16AnestheticsPhase 27385
17Anesthetics, GeneralPhase 22274
18Antihypertensive AgentsPhase 23618
19Anesthetics, InhalationPhase 2511
20
Dopamineapproved308462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
21
Bupropionapproved30834841-39-9444
Synonyms:
( -)-2-(tert-Butylamino)-3'-chloropropiophenone
( -)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
(+-)-Bupropion
.alpha.-(tert-Butylamino)-m-chloropropiophenone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
2-(Tert-Butylamino)-3'-chloropropiophenone
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
34841-36-6 (hydrochloride)
34841-39-9
34911-55-2
AB00053756
AC-197
AC1L198Y
AMFEBUTAMONE HCl
Amfebutamon
Amfebutamona
Amfebutamona [INN-Spanish]
Amfebutamone
Amfebutamonum
Amfebutamonum [INN-Latin]
Aplenzin
BPBio1_000042
BRD-A05186015-003-05-7
BRN 2101062
BSPBio_000038
BSPBio_002247
Budeprion
Buproban
Bupropion
Bupropion (INN)
Bupropion (Old RN)
Bupropion (USAN)
Bupropion Hcl
Bupropion Hydrochloride
Bupropion SR
Bupropion [INN:BAN]
Bupropion hydrocloride
C06860
CHEBI:3219
CHEMBL894
CID444
CPD000472526
D07591
DB01156
 
DivK1c_007050
Elont
HMS2051G10
HMS2089G14
Jsp006301
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
KBioGR_001168
KBioSS_002143
L000725
LS-122817
Lopac0_000166
MLS001424015
MolPort-003-845-432
NCGC00015122-06
NCGC00089751-02
NCI60_002714
NSC315851
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
SAM001246699
SMR000472526
SPBio_001817
SPBio_002257
SpecPlus_000954
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
Spectrum_001663
TL8002604
UNII-01ZG3TPX31
Wellbatrin
Wellbutrin
Wellbutrin SR
Wellbutrin XL
Wellbutrin Xl
Zyban
alpha-(tert-butylamino)-m-chloropropiophenone
amfebutamonum
bupropion
22
Mechlorethamineapproved30951-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
23
Caffeineapproved, Nutraceutical33958-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
24Neurotransmitter Agents14795
25
26Neurotransmitter Uptake Inhibitors2857
27Psychotropic Drugs5501
28Vitamins3857
29Dopamine Uptake Inhibitors925
30Dopamine Agents3084
31Antidepressive Agents2367
32Antidepressive Agents, Second-Generation1087
33Antidepressive Agents, Tricyclic250
34Cytochrome P-450 CYP2D6 Inhibitors602
35Cytochrome P-450 Enzyme Inhibitors3036
36Thrombin269
37CalamusNutraceutical344

Interventional clinical trials:

(show all 24)
idNameStatusNCT IDPhase
1Statins and Endothelial Function in Patients With Coarctation of the AortaTerminatedNCT00767572Phase 4
2Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the AortaCompletedNCT01278303Phase 2
3Effect of Strategy for Blood Pressure Control on Cerebral Oxygen Balance During Aortic Coarctation Repair: A Randomized StudyCompletedNCT00535808Phase 2
4Radiation-Free Heart Catheterization Using MRIRecruitingNCT02739087Phase 1
5Coarctation Of the Aorta Stent TrialCompletedNCT00552812
6MRI Assessment of RV Function: Patients With TOF or Aortic CoarctationCompletedNCT00277901
7Evaluation of Vascular Pathology With 3D, Time-Resolved Phase Contrast Magnetic Resonance Imaging (MRI)CompletedNCT00722904
8Cerebral Perfusion During Neonatal Cardiac SurgeryCompletedNCT01032876
9A Pilot Study of Thrombin Generation Changes in Neonates Undergoing Placement of a Blalock-Taussig ShuntCompletedNCT01340378
10Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
11Bupropion & Cardio Birth Defect (Slone)CompletedNCT01597661
12Study of the Corelation Between Circulating Nuclearsome and SIRS Happened After Congential Cardiac SurgeryCompletedNCT02325765
13Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic ResonanceRecruitingNCT02161471
14Cardiac Remodeling and Circulating Biomarkers in Pediatric Left Ventricular Pressure Loading LesionsRecruitingNCT02545790
15National Congenital Heart Disease AuditRecruitingNCT02303535
16Genetic Analysis of PHACE Syndrome (Hemangioma With Other Congenital Anomalies)RecruitingNCT01016756
17T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart DiseaseRecruitingNCT02350829
18Large Diameter Advanta™ V12 Covered Stent Trial for Coarctation of the AortaActive, not recruitingNCT00978952
19National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular ConditionsActive, not recruitingNCT01322165
20Longitudinal Study of Neurologic, Cognitive, and Radiologic Outcomes of PHACE SyndromeActive, not recruitingNCT01018082
21Proof of Concept of Model Based Cardiovascular PredictionEnrolling by invitationNCT02591940
22Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the AortaEnrolling by invitationNCT02700737
23Surgical Outcomes in Pediatric Patients With Coarctation and VSDTerminatedNCT00327795
24Aortic Arch ReconstructionTerminatedNCT00277940

Search NIH Clinical Center for Aortic Coarctation

Genetic Tests for Aortic Coarctation

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Anatomical Context for Aortic Coarctation

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MalaCards organs/tissues related to Aortic Coarctation:

33
Heart, Prostate, Breast, Lung, Kidney, Endothelial, Spinal cord

Animal Models for Aortic Coarctation or affiliated genes

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MGI Mouse Phenotypes related to Aortic Coarctation:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053757.3ACE, ADRB1, ADRB2, AGT, AGTR1, CYP11B2
2MP:00053677.3ACE, AGT, AGTR1, CYP11B2, EDN1, FBN1
3MP:00053797.3ACE, ADRB1, ADRB2, CYP11B2, EDN1, FBN1
4MP:00053697.1ADRB1, ADRB2, AGT, EDN1, FBN1, NOS3
5MP:00053876.8ACE, ADRB2, AGT, AGTR1, CYP11B2, FBN1
6MP:00036316.6ADRB2, AGT, AGTR1, CYP11B2, EDN1, FBN1
7MP:00107686.3ACE, ADRB1, AGT, AGTR1, EDN1, FBN1
8MP:00053766.0ACE, ADRB1, ADRB2, AGT, AGTR1, CYP11B2
9MP:00053785.8ACE, ADRB1, ADRB2, AGT, AGTR1, CYP11B2
10MP:00053855.3ACE, ADRB1, ADRB2, AGT, AGTR1, CYP11B2

Publications for Aortic Coarctation

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Articles related to Aortic Coarctation:

(show top 50)    (show all 593)
idTitleAuthorsYear
1
Complete aortic coarctation. (26852306)
2016
2
Augmentation of the Lesser Curvature With an Autologous Vascular Patch in Complex Aortic Coarctation and Interruption. (27021030)
2016
3
Familial aortic coarctation: a rare cause of refractory hypertension in the elderly: a case report. (25634191)
2015
4
Aortic Coarctation Diagnosed During Pregnancy in a Woman With Repaired Tetralogy of Fallot. (26354665)
2015
5
Is Intracardiac Echocardiography Essential for Monitoring Stent Deployment across Aortic Coarctation? (25684662)
2015
6
Impact of ascending to descending aortic bypass for aortic coarctation on 3-dimensional hemodynamics. (25779545)
2015
7
Percutaneous treatment of aortic coarctation with new generation self expandable stent system and the images of 320-slice tomographic angiography. (25756570)
2015
8
Pressure fields by flow-sensitive, 4D, velocity-encoded CMR in patients with aortic coarctation. (25212797)
2014
9
Transcatheter aortic valve implantation in aortic coarctation. (22215496)
2013
10
Continuous cerebral and myocardial perfusion during one-stage repair for aortic coarctation with ventricular septal defect. (23132178)
2013
11
Aortic coarctation and coronary artery disease: the XY factor. (22675159)
2012
12
Different transcatheter strategies for aortic coarctation associated with patent ductus arteriosus. (22929832)
2012
13
Surgical versus percutaneous treatment of aortic coarctation: new standards in an era of transcatheter repair. (23253276)
2012
14
Neurohormonal activity and vascular properties late after aortic coarctation repair. (21429604)
2012
15
Delayed onset of anterior spinal artery syndrome after repair of aortic coarctation. (22858787)
2012
16
Staged hybrid treatment of complex ascending aortic and distal aortic arch pseudoaneurysm after repair of aortic coarctation. (18948867)
2011
17
Prevalence of associated cardiovascular abnormalities in 500 patients with aortic coarctation referred for cardiovascular magnetic resonance imaging to a tertiary center. (21512788)
2011
18
Therapy refractory hypertension in adults: aortic coarctation has to be ruled out. (21475399)
2011
19
Aortic coarctation in the presence of capillary hemangioma. (21764546)
2011
20
External aortic diameter ratios: a reliable method to diagnose preductal aortic coarctation. (21609160)
2011
21
Redo sternotomy for extra-anatomical correction of aortic coarctation and mitral repair in an adult after failed endovascular treatment. (21780060)
2011
22
Surgical treatment for aortic coarctation with chronic type B dissection: report of a case. (23555479)
2011
23
Interrupted aortic arch and aortic coarctation: two similar entities. (20200652)
2010
24
Isolated aortic coarctation: experience in 100 consecutive patients. (20391897)
2010
25
Correction of aortic coarctation with interposition of a tube in a 12 years-old child. (21340394)
2010
26
Polysplenia/heterotaxy syndrome associated with aortic coarctation and multiple venous anomalies: multidetector computed tomography findings. (20484074)
2010
27
Technique of interventional repair in adult aortic coarctation. (20223618)
2010
28
A case of asymptomatic high-grade aortic coarctation. (21687218)
2009
29
Repair of aortic coarctation in an adult by direct aortoplasty. (19917797)
2009
30
A late presentation of Dandy-Walker malformation and aortic coarctation. (20019621)
2009
31
Sudden onset of sharp left-sided chest pain and hemoptysis in a young man with a history of childhood aortic coarctation repair. (18834811)
2009
32
What is the preferred therapy for patients with aortic coarctation--the standard gamble and decision analysis versus real results? (18093361)
2008
33
Surgical treatment of aortic coarctation in adults: Beneficial effect on arterial hypertension. (19039758)
2008
34
Mitral valve replacement with the beating heart technique in a patient with previous bypass graft from ascending to descending aorta due to aortic coarctation. (18304132)
2008
35
Moyamoya disease and aortic coarctation in a patient with common brachiocephalic trunk. (17347086)
2007
36
Aortic coarctation diagnosed by 64-slice computed tomography angiography. (17980292)
2007
37
Endovascular treatment of aortic coarctation in an adult with isthmic hypoplasia. (17484542)
2007
38
Reversibility of changes in hepatic vessels after correction of experimental aortic coarctation. (17152376)
2006
39
Right aortic coarctation and ventricular septal defect: an unusual cause of tracheal compression in infancy. (18377543)
2006
40
Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression. (15589970)
2005
41
Images in cardiology. Collateral circulation in aortic coarctation shown by 64 channel multislice computed tomography angiography. (16230439)
2005
42
Aortic coarctation endarteritis in an adult: case report with cardiovascular magnetic resonance imaging findings and review of the literature. (15712067)
2005
43
Asymptomatic aortic coarctation associated with loss of luminal continuity and intercostal artery aneurysm. (15041948)
2004
44
Percutaneous balloon dilatation of mitral valve stenosis and aortic coarctation. (12454343)
2002
45
An unusual type of combined aortic coarctation due to fibromuscular dysplasia. (10386705)
1999
46
Aortic coarctation, multiple ventricular septal defects, and anomalous coronary artery arising from the right pulmonary artery. (9451072)
1998
47
Functional aortic coarctation caused by thrombosis within a thoracic aortic aneurysm. (1572887)
1992
48
Scimitar syndrome associated with patent ductus arteriosus, aortic coarctation and irreversible pulmonary hypertension. (4236474)
1968
49
50

Variations for Aortic Coarctation

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Expression for genes affiliated with Aortic Coarctation

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Search GEO for disease gene expression data for Aortic Coarctation.

Pathways for genes affiliated with Aortic Coarctation

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Pathways related to Aortic Coarctation according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
19.6AGT, EDN1
29.4AGTR1, EDN1, NOS3
3
Show member pathways
9.4ACE, AGT, GNB3
49.3ADRB1, ADRB2
59.3ADRB1, EDN1, NOS3
6
Show member pathways
9.2AGT, AGTR1, GNB3
79.0ADRB1, ADRB2, GNB3
88.6ADRB1, ADRB2, AGTR1, NOS3
9
Show member pathways
8.6ADRB1, ADRB2, AGTR1, NOS3
10
Show member pathways
8.6ACE, AGT, AGTR1, CYP11B2, NOS3
11
Show member pathways
8.5AGT, AGTR1, EDN1, GNB3, NOS3
12
Show member pathways
8.4ADRB1, ADRB2, GNB3, GRK4, NOS3
138.1ACE, ADRB1, ADRB2, AGT, AGTR1
14
Show member pathways
8.1ADRB1, ADRB2, AGT, EDN1, GNB3

GO Terms for genes affiliated with Aortic Coarctation

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Biological processes related to Aortic Coarctation according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1regulation of systemic arterial blood pressure by endothelinGO:000310010.5EDN1, NOS3
2regulation of renal output by angiotensinGO:000201910.4ACE, AGT
3blood vessel remodelingGO:000197410.2ACE, AGT
4positive regulation of endothelial cell migrationGO:001059510.2AGT, EDN1
5regulation of blood vessel size by renin-angiotensinGO:000203410.2AGT, AGTR1
6artery smooth muscle contractionGO:001482410.2AGT, EDN1
7positive regulation of nitric oxide biosynthetic processGO:004542910.1AGT, EDN1
8vasoconstrictionGO:004231010.1AGT, EDN1
9positive regulation of cholesterol esterificationGO:001087310.1AGT, AGTR1
10response to dexamethasoneGO:007154810.1ADRB2, EDN1
11positive regulation of cellular protein metabolic processGO:003227010.0AGT, AGTR1
12positive regulation of macrophage derived foam cell differentiationGO:001074410.0AGT, AGTR1
13positive regulation of cardiac muscle hypertrophyGO:001061310.0AGT, EDN1
14positive regulation of renal sodium excretionGO:003581510.0AGT, EDN1
15vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressureGO:000202510.0ADRB1, ADRB2
16positive regulation of reactive oxygen species metabolic processGO:20003799.9AGT, AGTR1
17brown fat cell differentiationGO:00508739.9ADRB1, ADRB2
18regulation of sensory perception of painGO:00519309.9ADRB2, EDN1
19regulation of blood pressureGO:00082179.7AGT, EDN1, NOS3
20regulation of extracellular matrix assemblyGO:19012019.6AGT, NOTCH1
21calcium-mediated signalingGO:00197229.5AGTR1, EDN1
22positive regulation of vasodilationGO:00459099.4ADRB2, AGT, NOS3
23in utero embryonic developmentGO:00017019.3EDN1, NOS3, NOTCH1
24heart developmentGO:00075079.2EDN1, FBN1, NOTCH1
25negative regulation of ossificationGO:00302799.1ADRB2, NOTCH1
26cell surface receptor signaling pathwayGO:00071669.1ADRB2, AGT, EDN1
27cell-cell signalingGO:00072679.1ADRB1, AGT, EDN1
28regulation of vasoconstrictionGO:00192298.9ACE, AGT, AGTR1
29regulation of cell proliferationGO:00421278.7AGT, AGTR1, NOTCH1

Sources for Aortic Coarctation

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet