MCID: APC004
MIFTS: 32

Apocrine Adenocarcinoma malady

Endocrine, Cancer categories

Summaries for Apocrine Adenocarcinoma

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33MalaCards
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MalaCards: Apocrine Adenocarcinoma, also known as apocrine gland carcinoma, is related to adenocarcinoma and vulvar apocrine adenocarcinoma. An important gene associated with Apocrine Adenocarcinoma is PTHLH (parathyroid hormone-like hormone). The compounds trilostane and onapristone have been mentioned in the context of this disorder. Affiliated tissues include lymph node, colon and breast.

Aliases & Classifications for Apocrine Adenocarcinoma

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Endocrine


Aliases & Descriptions:

apocrine adenocarcinoma 8 61
apocrine gland carcinoma 8 61
carcinoma of the apocrine gland 8
apocrine carcinoma 8


External Ids:

Disease Ontology8 DOID:4933
SNOMED-CT57 57141000

Related Diseases for Apocrine Adenocarcinoma

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Apocrine Adenocarcinoma:



Diseases related to apocrine adenocarcinoma

Clinical Features for Apocrine Adenocarcinoma

Drugs & Therapeutics for Apocrine Adenocarcinoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Apocrine Adenocarcinoma

Anatomical Context for Apocrine Adenocarcinoma

Sources:
33MalaCards
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MalaCards organs/tissues related to Apocrine Adenocarcinoma:

33
Lymph node, Colon, Breast, Skin, Ovary

Animal Models for Apocrine Adenocarcinoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Apocrine Adenocarcinoma

Sources:
51PubMed
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Articles related to Apocrine Adenocarcinoma:

(show all 39)
idTitleAuthorsYear
1
Apocrine adenocarcinoma of the vulva. (24179652)
2013
2
Apocrine adenocarcinoma of the eyelid: case series and review. (24217473)
2013
3
Locally recurrent penile apocrine carcinoma initially diagnosed as metastatic adenocarcinoma of colon. (24385708)
2013
4
Case Report: Differential Diagnosis Between Primary Cutaneous Apocrine Adenocarcinoma Versus Extramammary or Metastatic Breast Adenocarcinoma. (23863550)
2013
5
Primary apocrine adenocarcinoma of the eyelid. (22571743)
2012
6
Cutaneous apocrine adenocarcinoma: defining epidemiology, outcomes, and optimal therapy for a rare neoplasm. (21913192)
2012
7
The elusive differential diagnosis of cutaneous apocrine adenocarcinoma vs. metastasis: the current role of clinical correlation. (19784530)
2009
8
Vulvar apocrine adenocarcinoma: a case with nodal metastasis and intranodal mucinous differentiation. (18842349)
2009
9
Primary apocrine adenocarcinoma of the scrotum with distant metastasis: a case report. (19796468)
2009
10
Localised radiotherapy for a ferret with possible anal sac apocrine adenocarcinoma. (18631226)
2008
11
Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. (18982051)
2008
12
Apocrine adenocarcinoma of the nipple: a case report. (18700029)
2008
13
Invasive primary ductal apocrine adenocarcinoma of axilla: a case report with immunohistochemical profiling and a review of literature. (18713586)
2008
14
Infiltrating apocrine adenocarcinoma with extramammary pagetoid spread. (17375797)
2007
15
Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. (17101482)
2006
16
Apocrine adenocarcinoma of possible sweat gland origin in a male rabbit. (16961473)
2006
17
Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. (15677547)
2005
18
Primary apocrine adenocarcinoma with neuroendocrine differentiation occurring on the pubic skin. (14996118)
2004
19
Apocrine adenocarcinoma of the nipple: a case report. (15469170)
2004
20
Aspiration biopsy in a case of apocrine adenocarcinoma with foam cells (myoblastomatoid or histiocytoid adenocarcinoma). (11992376)
2002
21
Apocrine adenocarcinoma of the eyelid with aggressive biological behavior: report of a case. (11940224)
2002
22
Apocrine adenocarcinoma in a golden hamster. (11767064)
2001
23
Adenocarcinoma with signet ring cells of the axilla showing apocrine features: a case report. (10027525)
1999
24
Radiologic case study. Apocrine adenocarcinoma. (9845457)
1998
25
Dependence of humoral hypercalcemia of malignancy on parathyroid hormone-related protein expression in the canine anal sac apocrine gland adenocarcinoma (CAC-8) nude mouse model. (9754539)
1998
26
Apocrine adenocarcinoma presenting as a large ulcerated axillary mass. (9236879)
1997
27
Parathyroid hormone/parathyroid hormone-related protein receptor expression in nude mice with a transplantable canine apocrine adenocarcinoma (CAC-8) and humoral hypercalcaemia of malignancy. (9135577)
1997
28
A case of apocrine adenocarcinoma associated with hamartomatous apocrine gland hyperplasia of both axillae. (8037297)
1994
29
Apocrine adenocarcinoma arising in cystic teratoma of the ovary. (8503739)
1993
30
Apocrine adenocarcinoma arising in Moll gland cystadenoma. (8233400)
1993
31
Complex adnexal tumor of the primary epithelial germ with distinct patterns of superficial epithelioma with sebaceous differentiation, immature trichoepithelioma, and apocrine adenocarcinoma. (1510222)
1992
32
Usefulness of paradoxical Con A staining for diagnosis of papillary adenocarcinoma of the apocrine anal sac gland in the dog. (1721547)
1991
33
Apocrine adenocarcinoma of the bilateral axillae. (1785351)
1991
34
Apocrine adenocarcinoma: case report and review of the literature. (2341662)
1990
35
Extramammary Paget's disease: comparative histopathologic studies of intraductal carcinoma of the breast and apocrine adenocarcinoma. (2175320)
1990
36
Identification of parathyroid hormone-related protein in canine apocrine adenocarcinoma of the anal sac. (2345942)
1990
37
Humoral hypercalcemia of malignancy in nude mouse model of a canine adenocarcinoma derived from apocrine glands of the anal sac. Biochemical, histomorphometric, and ultrastructural studies. (3012199)
1986
38
Apocrine adenocarcinoma of the vulva with associated Paget's disease. Diagnosis of lymph node metastases by fine needle aspiration biopsy. (6322492)
1984
39
Paget's disease of the vulva with underlying apocrine adenocarcinoma and local lymph node invasion. (6269104)
1981

Genetic Variations for Apocrine Adenocarcinoma

Expression for genes affiliated with Apocrine Adenocarcinoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Apocrine Adenocarcinoma

Search GEO for disease gene expression data for Apocrine Adenocarcinoma.

Pathways for genes affiliated with Apocrine Adenocarcinoma

Compounds for genes affiliated with Apocrine Adenocarcinoma

Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 60Tocris Bioscience, 50PharmGKB, 24HMDB
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Compounds related to Apocrine Adenocarcinoma according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1trilostane45 1110.7HPGD, PGR
2onapristone45 2910.6PGR, HPGD
3steroidal459.6PGR, HPGD
4sodium dodecylsulfate459.5PTHLH, PGR
5mifepristone45 60 29 1112.5PGR, HPGD
6prostaglandin459.5PTHLH, HPGD
7cyclophosphamide45 50 1111.4PGR, PTHLH
8thyroxine45 2410.3PGR, PTHLH
9progestins459.2PGR, PIP
10progestin459.2PTHLH, PGR, HPGD
11endotoxin459.2PTHLH, HPGD
12ribonucleic acid459.2PTHLH, PGR, HPGD
13indomethacin45 60 29 1112.2HPGD, PGR, PTHLH
14dexamethasone45 50 29 1112.0HPGD, PGR, PTHLH
15alanine458.9PTHLH, PGR, HPGD
16tamoxifen45 50 29 1111.8PTHLH, PGR, PIP
17estradiol45 11 2410.8PIP, PGR, PTHLH
18paraffin458.8PTHLH, PGR, PIP
19dihydrotestosterone45 29 11 2411.4PTHLH, PGR, HPGD, PIP
20progesterone45 60 29 11 2412.4PIP, HPGD, PGR, PTHLH
21testosterone45 60 11 2411.4PTHLH, PGR, HPGD, PIP
22steroid458.4PTHLH, PGR, HPGD, PIP
23estrogen458.4PIP, HPGD, PGR, PTHLH

GO Terms for genes affiliated with Apocrine Adenocarcinoma

Sources:
16Gene Ontology
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Biological processes related to Apocrine Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1female pregnancyGO:0075659.5PTHLH, HPGD

Products for genes affiliated with Apocrine Adenocarcinoma

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Sources for Apocrine Adenocarcinoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet