MCID: APR001
MIFTS: 38

Apraxia malady

Categories: Rare diseases, Fetal diseases

Aliases & Classifications for Apraxia

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Summaries for Apraxia

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NIH Rare Diseases:45 Apraxia is a neurological disorder characterized by the inability to perform tasks or movements, despite having the desire and physical ability to perform them. it is caused by damage to the brain, especially the parietal lobe, and can arise from many diseases, tumors, a stroke, or traumatic brain injury. in some cases it is present from birth. there are several types of apraxia, which may occur alone or together. these include:buccofacial or orofacial apraxia is the inability to carry out facial movements on demand. this may include licking the lips, sticking out the tongue, whistling, coughing, or winking. ideational apraxia is the inability to carryout learned, complex tasks with multiple, sequential movements. this may include dressing, eating, and bathing. ideomotor apraxia is the inability to perform a learned task (such as using a tool) or communicate using gestures (like waving good-bye). limb-kinetic apraxia is the inability to make fine, precise movements with an arm or leg. this may include buttoning a shirt or tying a shoe.  verbal apraxia is difficulty coordinating mouth and speech movements. verbal apraxia may be acquired or present from birth. constructional apraxia is the inability to copy, draw, or construct simple figures. oculomotor apraxia is difficulty moving the eyes on command. treatment of apraxia may include physical, speech, or occupational therapy. if apraxia occurs as a symptom of another disorder, treatment should be directed to the underlying condition. last updated: 1/4/2016

MalaCards based summary: Apraxia, also known as apraxias, is related to ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia and rolandic epilepsy, mental retardation, and speech dyspraxia. An important gene associated with Apraxia is APTX (Aprataxin), and among its related pathways is Organelle biogenesis and maintenance. Affiliated tissues include brain, tongue and eye, and related mouse phenotypes are renal/urinary system and cellular.

Disease Ontology:10 An agnosia that is a loss of the ability to map out physical actions in order to repeat them in functional activities.

NINDS:46 Apraxia (called "dyspraxia" if mild) is a neurological disorder characterized by loss of the ability to execute or carry out skilled movements and gestures, despite having the desire and the physical ability to perform them. Apraxia results from dysfunction of the cerebral hemispheres of the brain, especially the parietal lobe, and can arise from many diseases or damage to the brain.There are several kinds of apraxia, which may occur alone or together. The most common is buccofacial or orofacial apraxia, which causes the inability to carry out facial movements on command such as licking lips, whistling, coughing, or winking. Other types of apraxia include limb-kinetic apraxia (the inability to make fine, precise movements with an arm or leg), ideomotor apraxia (the inability to make the proper movement in response to a verbal command), ideational apraxia (the inability to coordinate activities with multiple, sequential movements, such as dressing, eating, and bathing), verbal apraxia (difficulty coordinating mouth and speech movements), constructional apraxia (the inability to copy, draw, or construct simple figures), and oculomotor apraxia (difficulty moving the eyes on command). Apraxia may be accompanied by a language disorder called aphasia. Corticobasal ganglionic degeneration is a disease that causes a variety of types of apraxia, especially in elderly adults.

Wikipedia:68 Apraxia is a motor disorder caused by damage to the brain (specifically the posterior parietal cortex),... more...

Related Diseases for Apraxia

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Diseases related to Apraxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 486)
idRelated DiseaseScoreTop Affiliating Genes
1ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia12.7
2rolandic epilepsy, mental retardation, and speech dyspraxia12.6
3ideomotor apraxia12.5
4childhood apraxia of speech12.5
5ataxia-oculomotor apraxia 312.5
6ataxia-oculomotor apraxia 412.4
7developmental dyspraxia12.4
8oculomotor apraxia cogan type12.4
9gait apraxia12.3
10rolandic epilepsy-speech dyspraxia syndrome12.3
11ocular motor apraxia, cogan type12.3
12ataxia-intellectual disability-oculomotor apraxia-cerebellar cysts syndrome12.2
13autosomal recessive cerebellar ataxia-pyramidal signs-nystagmus-oculomotor apraxia syndrome12.2
14primary progressive apraxia of speech12.2
15x-linked intellectual disability-ataxia-apraxia syndrome12.2
16spinocerebellar ataxia, autosomal recessive 112.0
17agnosia11.7
18balint syndrome11.6
19wieacker-wolff syndrome11.5
20alzheimer disease, type 311.5
21intellectual disability-developmental delay-contractures syndrome11.5
22progressive supranuclear palsy-progressive non-fluent aphasia syndrome11.2
23pick disease10.6
24setx10.6
25spastic paraplegia 46, autosomal recessive10.4APTX, SETX
26muscular dystrophy, limb-girdle, type 2c10.4APTX, SETX
27prostatitis10.4
28tick infestation10.3APTX, SETX
29ichthyosis prematurity syndrome10.3APTX, PIK3R5, SETX
30nephronophthisis 1, juvenile10.3AHI1, NPHP1
31prostate cancer10.3
32leukemia10.3
33joubert syndrome 1510.3
34joubert syndrome 2110.3
35joubert syndrome 610.3
36joubert syndrome 110.3
37joubert syndrome 1610.3
38joubert syndrome 210.3
39ataxia-telangiectasia10.3
40mitochondrial complex iii deficiency, nuclear type 210.3
41ataxia, spastic, 5, autosomal recessive10.3
42lung cancer10.3
43breast cancer10.3
44endotheliitis10.3
45parasitic protozoa infectious disease10.2APTX, SETX
46spastic ataxia10.2APTX, SETX
47hepatitis10.2
48progressive transformation of germinal centers10.2GRN, MAPT
49mosaic trisomy 210.2GRN, MAPT
50joubert syndrome with oculorenal anomalies10.2AHI1, INPP5E

Graphical network of the top 20 diseases related to Apraxia:



Diseases related to apraxia

Symptoms for Apraxia

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Drugs & Therapeutics for Apraxia

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Drugs for Apraxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TolvaptanapprovedPhase 484150683-30-0216237, 443894
Synonyms:
( -)-4'-((7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-o-tolu-m-toluidide
150683-30-0
7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine
AC1L50C9
C116664
CHEBI:327437
CHEMBL344159
CID216237
 
L001628
N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
OPC 41061
OPC-41061
PDSP1_001738
PDSP2_001721
Samsca
Tolvaptan
UNII-21G72T1950
benzazepine derivative, 32
2
AcetylcholineexperimentalPhase 468951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride
3Neurotransmitter AgentsPhase 4, Phase 214795
4Liver ExtractsPhase 43572
5Botulinum Toxins, Type APhase 4588
6OnabotulinumtoxinAPhase 4588
7AbobotulinumtoxinAPhase 4588
8Cholinergic AgentsPhase 43243
9IncobotulinumtoxinAPhase 4599
10Botulinum ToxinsPhase 4616
11VasopressinsPhase 4260
12Arginine VasopressinPhase 4264
13HormonesPhase 411748
14Natriuretic AgentsPhase 41403
15
GlycerolexperimentalPhase 319156-81-5753
Synonyms:
1,2,3-Trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerine
Glyceritol
Glycerol
 
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
16VitaminsPhase 33857
17MicronutrientsPhase 33901
18Trace ElementsPhase 33900
19Complement System ProteinsPhase 3190
20UbiquinonePhase 392
21Phase 3
22
Coenzyme Q10NutraceuticalPhase 3104303-98-05281915
Synonyms:
(all-E)-2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-2,5-Cyclohexadiene-1,4-dione
(all-E)-2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione
2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-Benzoquinone
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl- 2,5-Cyclohexadiene-1,4-dione
4-Ethyl-5-fluoropyrimidine
Aqua Q 10L10
Aqua Q10
Bio-Quinon
Bio-Quinone Q10
CoQ10
Coenzyme Q10
Ensorb
Kaneka Q10
Kudesan
 
Li-Q-Sorb
Liquid-Q
Neuquinon
Neuquinone
PureSorb Q 40
Q 10AA
Q-Gel
Q-Gel 100
Ubidecarenone
Ubiquinone 10
Ubiquinone 50
Ubiquinone Q10
Ubiquinone-10
Unbiquinone
Unispheres Q 10
23LecithinNutraceuticalPhase 363
24
DopamineapprovedPhase 2308462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
25
Memantineapproved, investigationalPhase 217219982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
26
BenzocaineapprovedPhase 216841994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
20/20 Topical Anesthetic
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Alcohol Prep Pads
Allegenal-m
Alpha-caine Topical Anesthetic
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anbesol Jr
Anbesol Maximum Strength
Anbesol Regular Strength
Anestenka
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthetic
Anesthone
Atopalm Oral Pain Relief
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Baby Anestenka
Baby Sensigel
Baby Sensigel Night Time Formula
Baby Teething Oral Pain Reliever
Bactimicina For Sore Throat
Bencocaine Topical Anesthetic
Bensokain
Benz O Sthetic
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzodent
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
Boil Ease
Boy Butter Desensitizing Lubricant
Boy Butter Extreme Desensitizing Lubricant
Boy Butter Extreme H2O Desensitizing Lubricant
Brace Relief
Budpak Baby Teething Oral Pain Reliever
Budpak Oral Maximum Strength
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Carmex Cold Sore Treatment External Analgesic
Caswell No. 430A
Cepacol Fizzlers
Cepacol Sensations Hydra
Cepacol Sensations Sore Throat Hydra citrus splash
Cepacol Sensations Warming
Certus Sting Relief Prep Pad
Chloraseptic
Chloraseptic Warming Sore Throat
Colgate Orabase
Comfortcaine Topical Anesthetic
Cvs Fast Acting Baby Teething
Cvs Maximum Strength
Cvs Maximum Strength Boil Relief
Cvs Oral Anesthetic
Cvs Pharmacy Instant Toothache
Cvs Pharmacy Maximum Strength
Cvs Pharmacy Mouth Sore Gel
Cvs Pharmacy Nighttime Oral Pain Relief
D001566
D00552
DB01086
Dental Relief
Dentek Instant Pain Relief Maximum Strength
Dermoplast
Diet Ayds
DivK1c_000932
Dollar General Toothache Relief
Dukal Sting Relief Pad
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Finafta Baby
Finafta MultiOral
Formate, Benzocaine
Gelato Topical Anesthetic
Good Neighbor Pain Relief
Goodsense Oral Pain Relief
Gps Topical Anesthetic
Gumnumb Topical Anesthetic
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Heb Severe Toothache
Herbasoul Male Genital Desensitizer Cream
 
Hurricaine
Hurricaine Topical Anesthetic
Hurricaine Topical Anesthetic Gel
Hurricaine Topical Anesthetic Liquid
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
Insect Bite Relief
Instant Toothache Pain Relief
Intense Cvs Intense Toothache
Iodent Maximum Strength Oral Analgesic
Ismile Topical Anesthetic
Jianze Sting Relief Pads
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Kank-a Mouth Pain
Keloform
Kmart Smart Sense
Kroger Toothache Pain Relief
LS-35847
Leader Oral Analgesic
Little Colds Sore Throat Relief Melt Aways
MLS001331704
MLS002153970
Makesense Junior Pain Relief
Makesense Pain Relief
Male Desensitizer Pleasure Balm
Mandelay Male Genital Desensitizer
Mark 3
Methanesulfonate, Benzocaine
MolPort-000-871-526
Mouth Sore Medication
Mouth Sore Relief Applicator
Mouth Sore Relief Professional Strength
My Fair Baby Instant Pain Relief
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Nene Dente
Norcain
Norcaine
Norcainum
Opahl
Opahl Dye Free
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orajel For All Mouth Sores Maximum Strength
Orajel For Cold Sores
Orajel For Toothache Maximum Strength
Orajel Instant Pain Relief Maximum Strength
Orajel Instant Pain Relief Regular Strength
Orajel Instant Relief For Teething Pain
Orajel Instant Relief For Teething Pain Cooling Cucumber
Orajel Instant Relief For Teething Pain Daytime Nighttime Twin Pack
Orajel Instant Relief For Teething Pain Longer Lasting
Orajel Maximum Strength
Orajel Nighttime Instant Relief For Teething Pain Longer Lasting Extra Strength
Orajel Severe Toothache Maximum Strength Fast-Acting Formula
Oral Analgesic Maximum Strength
Oral B Instant Pain Relief
Oral Gel Maximum Strength
Oral Pain Relief Anesthetic Anesthetic
Oral Pain Reliever
Oralabs Cold Sore Treatment
Orthesin
Otocain
Outgro
Pac-dent Top Gel
Pain Relief
Pain Relief Alcohol Swabs
Parathesin
Parathesin (TN)
Parathesine
Physicians Care Sting Relief Pad
Pleasure Balm Kama Sutra
Preboost
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
Purelife Topical Anesthetic
Quality Choice Maximum Strength Oral Pain Relieving
Red Cross Oral Pain Relief
Rexall Maximum Strength
Rite Aid Baby Care
Rite Aid Liquid Anesthetic Oral Pain Relief
Rite Aid Maximum Strength
Rite Aid Oral Pain Reliever
Rite Aid Professional Strength
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Sally Hansen Ouch-relief Numbing Wipes
Sally Hansen Ouch-relief Wax Kit
Sally Hansen Ouch-relief Wax Strip Kit
Sensigel
Severe Oral Pain Reliever
Sheffield Baby Teething Gel
Sheffield Pain Relief
Shunga Male Genital Desensitizer
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Sting Relief Medicated Pad
Sting Relief Pads
Tanac
Terrasil Boil Pain Relief
Tiger Supply Inc Topical Anesthetic
Top Quality Mfg. Topical Anesthetic
Topcaine
Topcare Maximum Strength
Topical Anesthetic Banana
Topical Anesthetic Bubble Gum
Topical Anesthetic Cherry
Topical Anesthetic Mint
Topical Anesthetic Pina Colada
Topical Anesthetic Raspberry
Topical Anesthetic Strawberry
UNII-U3RSY48JW5
Ultracare Anesthetic Bubble Gum
Ultracare Anesthetic Butter Rum
Ultracare Anesthetic Creme de Menthe
Ultracare Anesthetic Pina Colada
Ultracare Anesthetic Walterberry
WLN: ZR DVO2
Walgreens Baby Teething
Walgreens Intense Toothache
Walgreens Maximum Strength
Walgreens Pain Relieving For Boils
Walgreens Severe Oral Pain Reliever
Walgreens Severe Toothache Relief
Winco Foods Maximum Strength Oral Analgesic
ZINC12358719
Zilactin-b
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
27Excitatory Amino AcidsPhase 21109
28Dopamine AgentsPhase 23084
29Excitatory Amino Acid AntagonistsPhase 21095
30Antiparkinson AgentsPhase 21312
31tannic acidNutraceuticalPhase 21684
32Fluorodeoxyglucose F18Phase 1356
33
CorticosteronePhase 1950-22-65753
Synonyms:
11,21-Dihydroxypregn-4-ene-3,20-dione
11,21-Dihydroxyprogesterone
11-Hydroxycorticoaldosterone
 
17-Deoxycortisol
4-Pregnene-11 Corticosteron
Corticosterone
Kendall'S compound B
Reichstein'S substance H
34DeoxyglucosePhase 197
35vitamin d1524
36Bone Density Conservation Agents2600

Interventional clinical trials:

(show all 39)
idNameStatusNCT IDPhase
1The Use of Botox in Advanced Parkinson's Patients Experiencing PainActive, not recruitingNCT02472210Phase 4
2Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and HyponatremiaTerminatedNCT01890694Phase 4
3Evolution of Albumin on AOA1 Patients Supplemented With Coenzyme Q10Active, not recruitingNCT02333305Phase 3
4Electrical Polarization of the Brain in Corticobasal SyndromeCompletedNCT00273897Phase 2
5A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)CompletedNCT01372449Phase 2
6Treatment Intensity - Apraxia of SpeechRecruitingNCT02332915Phase 2
7Evaluating Anodal tDCS Preceding Aphasia TherapyRecruitingNCT02249819Phase 1, Phase 2
8A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's DiseaseActive, not recruitingNCT02260674Phase 2
9Treatment of Mitochondrial Dysfunction in Rett Syndrome With TriheptanoinNot yet recruitingNCT02696044Phase 2
10PiB PET Scanning in Speech and Language Based DementiasCompletedNCT01623284Phase 1
11A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of OutcomesRecruitingNCT01979159Phase 1
12Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)RecruitingNCT02554513Phase 1
13Treatments of Acquired Apraxia of SpeechActive, not recruitingNCT01483807Phase 1
14EEG and EMG Analysis of Ideomotor ApraxiaCompletedNCT00024999
15Occupational Therapy in Patients With Multiple SclerosisCompletedNCT01507636
16Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of SpeechCompletedNCT02094014
17Stuttering and Apraxia of Speech: the Efficacy of an Intervention ProgramCompletedNCT01097161
18Using fMRI to Understand the Roles of Brain Areas for Fine Hand MovementsCompletedNCT00063115
19Clinical Findings in General ParesisCompletedNCT00921648
20Orientation Agnosia: Clinical and Anatomical StudyCompletedNCT01304576
21Central Mechanisms in Speech Motor Control Studied With H215O PETCompletedNCT00001308
22Longitudinal Multi-Modality Imaging in Progressive Apraxia of SpeechRecruitingNCT01818661
23Intervention on Caregivers Caring for Patients Poststroke With Upper Limb ApraxiaRecruitingNCT02307019
24Construction-LBD (Constructional Apraxia in Alzheimer's Disease (AD) and Lewy Body's Dementia (LBD))RecruitingNCT01993628
25Action Observation Treatment (AOT) as a Rehabilitation ToolRecruitingNCT02235350
26Brain Biomarkers of Response to Treatment for Apraxia of SpeechRecruitingNCT02046941
27Gait and Alzheimer Interaction Tracking (GAIT) StudyRecruitingNCT01315717
28Alzheimer's Disease and Related DisordersRecruitingNCT01315704
29Study of Adherence and Effects of Balance Exercices (SIEL BLEU Associatio)RecruitingNCT01314638
30Clinical and Molecular Investigations Into CiliopathiesRecruitingNCT00068224
31Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic StrokeRecruitingNCT01644929
32Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral IschemiaRecruitingNCT00494689
33Exploring the Impact and Feasibility of a Pathway to Sport and Long-term Participation in Young PeopleRecruitingNCT02517333
34Deep Brain Stimulation for Patients With Dementia With Lewy BodiesRecruitingNCT02263937
35Cognitive Assessment for Stroke Patients: Reproductibility and Validity StudyRecruitingNCT01904799
36Functional Rehabilitation of Upper Limb Apraxia in Patients PoststrokeActive, not recruitingNCT02199093
37Scholar Performance and Praxis Assessment in Children With Rolandic EpilepsyActive, not recruitingNCT01046760
38Upper Limbs Intervention in Multiple SclerosisActive, not recruitingNCT02047825
39Blepharospasm ToolsNot yet recruitingNCT02780336

Search NIH Clinical Center for Apraxia

Genetic Tests for Apraxia

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Anatomical Context for Apraxia

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MalaCards organs/tissues related to Apraxia:

33
Brain, Tongue, Eye, Parietal lobe, Testes, Cortex, Lung

Animal Models for Apraxia or affiliated genes

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MGI Mouse Phenotypes related to Apraxia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.7AHI1, C5orf42, CC2D2A, INPP5E, MAPT, NPHP1
2MP:00053847.3AHI1, APTX, CC2D2A, GRN, INPP5E, MAPT
3MP:00053917.1AHI1, CC2D2A, GRN, INPP5E, MAPT, NPHP1

Publications for Apraxia

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Articles related to Apraxia:

(show top 50)    (show all 671)
idTitleAuthorsYear
1
Choroid plexus papilloma in a beluga whale (Delphinapterus leucas). (27216722)
2016
2
Cerebral lipid accumulation in Chanarin-Dorfman Syndrome. (25468645)
2015
3
Single-site laparoscopic colectomy for rectosigmoid cancer with middle aortic syndrome: report of a case. (26366350)
2015
4
Group A streptococcal endophthalmitis complicating a sore throat in a 2-year-old child. (25858925)
2015
5
Linear nevus sebaceous syndrome. (25506177)
2014
6
Serum sclerostin levels vary with season. (24248178)
2014
7
Molecular basis for DPY-30 association to COMPASS-like and NURF complexes. (25456412)
2014
8
The mononuclear phagocyte system in homeostasis and disease: a role for heme oxygenase-1. (24147608)
2014
9
Angiosarcoma of penis. (24351513)
2013
10
Mitral valve prolapse with left atrial enlargement out of proportion to mitral regurgitation. (22953664)
2012
11
Folliculitis induced by EGFR inhibitors, preventive and curative efficacy of tetracyclines in the management and incidence rates according to the type of EGFR inhibitor administered: a systematic literature review. (22426526)
2012
12
Genome-wide microRNA expression analysis of clear cell renal cell carcinoma by next generation deep sequencing. (22745662)
2012
13
Cloning and characterization of the osteoarthritis-associated gene DVWA. (21057832)
2011
14
Proteomic analysis of ovarian cancer proximal fluids: validation of elevated peroxiredoxin 1 in patient peripheral circulation. (21980378)
2011
15
Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes. (19909766)
2010
16
Human beta-defensin-2 increases cholinergic response in colon epithelium. (20229195)
2010
17
Cutaneous zygomycosis : major concerns. (20571161)
2010
18
Medical image. Severe headache when standing. Intracranial hypotension. (19319177)
2009
19
Interleukin-21 regulates expression of the immediate-early lytic cycle genes and proteins in Epstein-Barr Virus infected B cells. (19447148)
2009
20
Prooxidant-antioxidant balance, peroxide and catalase activity in the aqueous humour and serum of patients with exfoliation syndrome or exfoliative glaucoma. (18607617)
2008
21
P53-dependent suppression of the human calcyclin gene (S100A6): the role of Sp1 and of NFkappaB. (18714402)
2008
22
Freezing point depression of water in phospholipid membranes: a solid-state NMR study. (18991419)
2008
23
Limbic encephalitis as presentation of a SAP deficiency. (17620557)
2007
24
Ghrelin and leptin response to oral glucose challenge among antipsychotic drug-treated children. (18004125)
2007
25
Type-2 diabetic Lepr(db/db) mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia. (17127438)
2007
26
Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper. (16243960)
2006
27
Interleukins 6 and C-reactive protein for the diagnosis of late onset sepsis in the newborn infant]. (16767331)
2006
28
Granular cell tumor of the scrotum. (16150233)
2005
29
Neutrophils enhance invasion activity of human cholangiocellular carcinoma and hepatocellular carcinoma cells: an in vitro study. (15683434)
2005
30
Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar typhimurium systemic infection. (15664952)
2005
31
Luman is capable of binding and activating transcription from the unfolded protein response element. (15845366)
2005
32
Diffusion-weighted MR imaging in acute spinal cord ischemia. (15022011)
2004
33
Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization. (12610158)
2003
34
Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition. (14749532)
2003
35
Modulation of circulating endothelin-1 and big endothelin by nitric oxide inhalation following left ventricular assist device implantation. (12970246)
2003
36
Possible influence of glutathione S-transferase GSTT1 null genotype on age of onset of sporadic colorectal adenocarcinoma. (12682546)
2003
37
Histidine-rich glycoprotein plus zinc reverses growth inhibition of vascular smooth muscle cells by heparin. (12764609)
2003
38
Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity. (14616429)
2003
39
-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension. (11587161)
2001
40
Nerve growth factor protects oligodendrocytes from tumor necrosis factor-alpha-induced injury through Akt-mediated signaling mechanisms. (10748222)
2000
41
Analysis of vacA, cagA, and IS605 genotypes and those determined by PCR amplification of DNA between repetitive sequences of Helicobacter pylori strains isolated from patients with nonulcer dyspepsia or mucosa-associated lymphoid tissue lymphoma. (10364612)
1999
42
Novel pattern of P53 mutation in breast cancers from Austrian women. (7598762)
1995
43
Protective effects of basic fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil. (8481788)
1993
44
Protective effect of nickel chloride on superoxide damage: enhancement of CuZn superoxide dismutase affinity to the oxygen free radical. (8074791)
1993
45
Distribution of Crimean-Congo hemorrhagic fever viral antibody in Senegal: environmental and vectorial correlates. (2122750)
1990
46
Centrosomal proteins and lactate dehydrogenase possess a common epitope in human cell lines. (2434947)
1987
47
Spinal cord ischemia following operation for traumatic aortic transection. (3767513)
1986
48
'Isolated' pulmonary valve stenosis as part of more widespread cardiovascular disease. (944584)
1976
49
50

Variations for Apraxia

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Expression for genes affiliated with Apraxia

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Search GEO for disease gene expression data for Apraxia.

Pathways for genes affiliated with Apraxia

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Pathways related to Apraxia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
7.5AHI1, ARL13B, CC2D2A, INPP5E, NPHP1, TMEM216

GO Terms for genes affiliated with Apraxia

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Cellular components related to Apraxia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoskeletonGO:00058569.3INPP5E, NPHP1, TMEM216
2TCTN-B9D complexGO:00360388.9AHI1, TMEM216, TMEM231

Biological processes related to Apraxia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1polynucleotide 3 dephosphorylationGO:009850610.5APTX, PNKP
2positive regulation of neuron projection developmentGO:00109769.6GRN, INPP5E, SETX
3smoothened signaling pathwayGO:00072249.1ARL13B, CC2D2A
4organelle organizationGO:00069968.9ARL13B, CC2D2A, NPHP1

Molecular functions related to Apraxia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1polynucleotide 3-phosphatase activityGO:004640310.0APTX, PNKP

Sources for Apraxia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet