MCID: ARC007
MIFTS: 39

Arachnoid Cysts malady

Categories: Rare diseases, Neuronal diseases, Endocrine diseases, Fetal diseases

Aliases & Classifications for Arachnoid Cysts

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Sources:
46NIH Rare Diseases, 47NINDS, 52Orphanet, 25GTR, 66UMLS, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Arachnoid Cysts:

Name: Arachnoid Cysts 46 47 66
Intracranial Arachnoid Cysts 46 25 66
 
Arachnoid Cyst 52 25
Arachnoid Cysts, Intracranial 46

Characteristics:

Orphanet epidemiological data:

52
arachnoid cyst:
Inheritance: Autosomal recessive,Not applicable; Age of onset: Childhood; Age of death: normal life expectancy

Classifications:



External Ids:

Orphanet52 ORPHA2356
ICD10 via Orphanet29 G93.0
MESH via Orphanet38 D016080
UMLS via Orphanet67 C0078981

Summaries for Arachnoid Cysts

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NIH Rare Diseases:46 Arachnoid cysts are sacs filled with cerebrospinal fluid (csf) that are located between the brain or spinal cord and the arachnoid membrane, one of the three membranes that cover the brain and spinal cord. arachnoid cysts can be primary or secondary. primary arachnoid cysts are congenital (present at birth), resulting from abnormal development of the brain and spinal cord during early pregnancy. secondary arachnoid cysts are less common and result from head injuries, meningitis, tumors, or as a complication of brain surgery. signs and symptoms depend on the location and size of the cyst and may include headache, nausea and vomiting, seizures, hearing and visual disturbances, vertigo, and difficulties with balance and walking. although many affected individuals develop symptoms in the first year of life, some never develop symptoms. whether and how to treat the condition depends on the location and size of the cyst.  when treatment is recommended, it may include placing a shunt to drain the fluid; surgically removing the cyst membranes; or opening the cyst so the fluid can drain into the csf. last updated: 1/7/2016

MalaCards based summary: Arachnoid Cysts, also known as intracranial arachnoid cysts, is related to spinal intradural arachnoid cysts and pachygyria with mental retardation, seizures, and arachnoid cysts. An important gene associated with Arachnoid Cysts is FOXC2 (Forkhead Box C2), and among its related pathways is AGE-RAGE signaling pathway in diabetic complications. Affiliated tissues include spinal cord, brain and temporal lobe, and related mouse phenotype cardiovascular system.

NINDS:47 Arachnoid cysts are cerebrospinal fluid-filled sacs that are located between the brain or spinal cord and the arachnoid membrane, one of the three membranes that cover the brain and spinal cord.

Wikipedia:69 Arachnoid cysts are cerebrospinal fluid covered by arachnoidal cells and collagen that may develop... more...

Related Diseases for Arachnoid Cysts

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Graphical network of the top 20 diseases related to Arachnoid Cysts:



Diseases related to arachnoid cysts

Symptoms for Arachnoid Cysts

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Drugs & Therapeutics for Arachnoid Cysts

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Drugs for Arachnoid Cysts (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Menthol21842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol

Interventional clinical trials:

idNameStatusNCT IDPhase
190Yttrium Colloid for the Treatment of Cystic Sellar/Parasellar TumorsRecruitingNCT02081768Phase 3
2Study and Surgical Treatment of SyringomyeliaCompletedNCT00011245
3Treatment for Chronic Spinal Cord Injury: Surgery With Rehabilitation vs RehabilitationRecruitingNCT02663310

Search NIH Clinical Center for Arachnoid Cysts

Genetic Tests for Arachnoid Cysts

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Genetic tests related to Arachnoid Cysts:

id Genetic test Affiliating Genes
1 Arachnoid Cyst25
2 Arachnoid Cysts, Intracranial25

Anatomical Context for Arachnoid Cysts

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MalaCards organs/tissues related to Arachnoid Cysts:

34
Spinal cord, Brain, Temporal lobe, Pituitary, Cingulate cortex, Testis, Kidney

Animal Models for Arachnoid Cysts or affiliated genes

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MGI Mouse Phenotypes related to Arachnoid Cysts:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.3COL4A1, FOXC2, NRAS, SLC12A2

Publications for Arachnoid Cysts

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Articles related to Arachnoid Cysts:

(show top 50)    (show all 657)
idTitleAuthorsYear
1
Episodic Headache and Arachnoid Cyst Related Subdural Hematoma. (27197943)
2016
2
Prevalence and symptoms of intracranial arachnoid cysts: a population-based study. (26860092)
2016
3
Pediatric intraventricular arachnoid cysts in the body of lateral ventricle: surgical outcome and its embryologic background. (27492334)
2016
4
Detection of the Communicating Hole(s) of Spinal Extradural Arachnoid Cysts Using Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging. (25202934)
2014
5
Microsurgical fenestration and cystoperitoneal shunt through preauricular subtemporal keyhole craniotomy for the treatment of symptomatic middle fossa arachnoid cysts in children. (25142689)
2014
6
Surgical management of intracranial arachnoid cysts: clinical and radiological outcome. (23546896)
2013
7
Cluster headache and arachnoid cyst. (23419954)
2013
8
Bilateral retrocerebellar arachnoid cysts exerting mass effect and associated with cerebellar tonsillar ectopia in an otherwise healthy adult. (23615422)
2013
9
Benign extracerebral fluid collection in infancy as a risk factor for the development of de novo intracranial arachnoid cysts. (24093592)
2013
10
Symptomatic thoracic arachnoid cyst with coexisting tick paralysis: case report and review of the literature. (25531213)
2013
11
Endonasal management of sellar arachnoid cysts: simple cyst obliteration technique. (22283187)
2012
12
Surgical management strategies of intracranial arachnoid cysts: a single institution experience of 75 cases. (23015336)
2012
13
A case of an arachnoid cyst masquerading as corticobasal degeneration. (23061395)
2012
14
Transient paraplegia after accidental insertion of an epidural catheter into an arachnoid cyst. (21897183)
2011
15
Complete resolution of medically refractory temporal lobe epilepsy after arachnoid cyst fenestration. (22649891)
2011
16
Spinal extradural arachnoid cysts in lymphedema-distichiasis syndrome. (20535019)
2010
17
CSF overdrainage in shunted intracranial arachnoid cysts: a series and review. (19452154)
2009
18
Multiple extradural spinal arachnoid cysts: a case report and review of the literature. (19829999)
2009
19
Multiple extradural spinal arachnoid cysts causing diffuse myelomalacia of the spinal cord. (19901717)
2009
20
Prenatal sonographic and magnetic resonance imaging demonstration of a right midline arachnoid cyst associated with ventriculomegaly, colpocephaly, dilation of the third ventricle, absence of cavum septi pellucidi, agenesis of the corpus callosum and mega cisterna magna. (18400590)
2008
21
Intrasacral extradural arachnoid cysts. (18497497)
2008
22
Asymptomatic massive subdural hematoma in a patient with bitemporal agenesis and bilateral temporal arachnoid cysts. (18364667)
2008
23
Posterior fossa arachnoid cyst, tonsillar herniation, and syringomyelia in trichorhinophalangeal syndrome Type I. (18826365)
2008
24
Arachnoid cysts: spontaneous resolution distinct from traumatic rupture. Case report. (17608346)
2007
25
Arachnoid cyst with growth hormone deficiency. (17401272)
2007
26
Anterior cervical arachnoid cyst presenting with traumatic quadriplegia. (15007602)
2004
27
A new SPG4 mutation in a variant form of spastic paraplegia with congenital arachnoid cysts. (15159500)
2004
28
Apparent paradoxical vault changes with middle cranial fossa arachnoid cysts--implication for aetiology. (11895303)
2001
29
Lateral intrathoracic meningocele associated with a spinal intradural arachnoid cyst. (11549923)
2001
30
Children with bilateral temporal arachnoid cysts may have glutaric aciduria type 1 (GAT1); operation without knowing that may be harmful. (11086812)
2000
31
A case report of caudal regression syndrome associated with an intraspinal arachnoid cyst. (10705931)
1999
32
Anterior thoracic intradural arachnoid cysts. Case report and review of the literature. (17031914)
1999
33
Bilateral sensorineural deafness, partial agenesis of the corpus callosum, and arachnoid cysts in two sisters. (10449658)
1999
34
Peculiarities of intracranial arachnoid cysts: location, sidedness, and sex distribution in 126 consecutive patients. (10515470)
1999
35
Clinically asymptomatic glutaric aciduria type I in a 4 5/12-year-old girl with bilateral temporal arachnoid cysts. (9427159)
1997
36
Nontraumatic intradiploic arachnoid cysts--report of five cases. (1282679)
1992
37
Do arachnoid cysts grow? A retrospective CT volumetric study. (1922751)
1991
38
Intermittent downbeat nystagmus secondary to vermian arachnoid cyst with associated obstructive hydrocephalus. (1838553)
1991
39
Magnetic resonance imaging of arachnoid cysts. (2598110)
1989
40
Cysto-atrial shunt treatment of intracranial arachnoid cysts. (2642235)
1989
41
Arachnoid cysts of the middle cranial fossa: experience with 77 cases treated surgically. (3189009)
1988
42
Arachnoid cysts of the posterior fossa. Report of three cases. (6858736)
1983
43
Spinal intradural arachnoid cysts. (7110485)
1982
44
Arachnoid cysts--report of two adult cases in the interhemispheric fissure and over the cerebral convexity. (6176896)
1982
45
Multiple spinal arachnoid cysts: the role of oily contrast medium. (6264636)
1981
46
Dynamic study of arachnoid cysts with metrizamide. (7465036)
1980
47
Posterior fossa arachnoid cysts. (501222)
1979
48
The dysraphic state of the posterior fossa. Clinical review of the Dandy-Walker syndrome and the so-called arachnoid cysts. (536750)
1979
49
Clinical analysis of arachnoid cysts in the middle fossa. (514432)
1979
50
Cerebral arachnoid cysts in infants. (5935772)
1966

Variations for Arachnoid Cysts

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Copy number variations for Arachnoid Cysts from CNVD:

6 (show all 32)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
141643102182284821949193LossC10orf114Intracranial arachnoid cysts
241644102182284821949193LossC10orf140Intracranial arachnoid cysts
341645102182284821949193LossMLLT10Intracranial arachnoid cysts
457050116255772462669857LossSLC22A24Intracranial arachnoid cysts
56386512121446657121547275Copy numberCLIP1Intracranial arachnoid cysts
66386612121446657121547275Copy numberZCCHC8Intracranial arachnoid cysts
768816125172407351844567LossCSADIntracranial arachnoid cysts
868817125172407351844567LossIGFBP6Intracranial arachnoid cysts
968818125172407351844567LossSOAT2Intracranial arachnoid cysts
1068819125172407351844567LossSPRYD3Intracranial arachnoid cysts
1168820125172407351844567LossTENC1Intracranial arachnoid cysts
1270825126497848765093419GainITGB7Intracranial arachnoid cysts
1370828126497848765093419GainZNF740Intracranial arachnoid cysts
1486768146497848765093419InversionFUT8Intracranial arachnoid cysts
1592669154246849142598658Copy numberCASC4Intracranial arachnoid cysts
1692670154246849142598658Copy numberCTDSPL2Intracranial arachnoid cysts
171012201634316563522375Copy numberC16orf90Intracranial arachnoid cysts
181012211634316563522375Copy numberCLUAP1Intracranial arachnoid cysts
191013801635223753631656LossBTBD12Intracranial arachnoid cysts
201013821635223753631656LossNLRC3Intracranial arachnoid cysts
2110672617110700000LossTP53Intracranial arachnoid cysts
22112317173856062738814457LossLOC100130581Intracranial arachnoid cysts
23112318173856062738814457LossNBR1Intracranial arachnoid cysts
24112319173856062738814457LossTMEM106AIntracranial arachnoid cysts
251248201912057971228434LossSTK11Intracranial arachnoid cysts
26125526191424673414391382LossCD97Intracranial arachnoid cysts
27125527191424673414391382LossDDX39Intracranial arachnoid cysts
28227152764982076600621DeletionC7orf26Intracranial arachnoid cysts
29227153764982076600621DeletionGRID2IPIntracranial arachnoid cysts
30227154764982076600621DeletionZDHHC4Intracranial arachnoid cysts
3123369981270000019000000LossN33Intracranial arachnoid cysts
3223985684217520642281148Copy numberPLATIntracranial arachnoid cysts

Expression for genes affiliated with Arachnoid Cysts

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Search GEO for disease gene expression data for Arachnoid Cysts.

Pathways for genes affiliated with Arachnoid Cysts

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Pathways related to Arachnoid Cysts according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1COL4A1, NRAS

GO Terms for genes affiliated with Arachnoid Cysts

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Biological processes related to Arachnoid Cysts according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1patterning of blood vesselsGO:00015699.2COL4A1, FOXC2

Sources for Arachnoid Cysts

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet