Categories: Genetic diseases, Rare diseases, Neuronal diseases
Aliases & Descriptions for Arachnoiditis:
Orphanet epidemiological data:51
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy
Inheritance: autosomal dominant inheritance
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases
Rare neurological diseases
NIH Rare Diseases:45 Arachnoiditis describes a pain disorder caused by the inflammation of the arachnoid, one of the membranes that surround and protect the nerves of the spinal cord. the arachnoid can become inflamed because of an irritation from chemicals, infection from bacteria or viruses, as the result of direct injury to the spine, chronic compression of spinal nerves, or complications from spinal surgery or other invasive spinal procedures. inflammation can sometimes lead to the formation of scar tissue and adhesions, which cause the spinal nerves to “stick” together. if arachnoiditis begins to interfere with the function of one or more of these nerves, it can cause a number of symptoms, including numbness, tingling, and a characteristic stinging and burning pain in the lower back or legs. adhesive arachnoiditis is the most severe form, characterized by debilitating, intractable neurogenic back and limb pain and a range of other neurological problems. arachnoiditis is difficult to treat and long-term outcomes are unpredictable. a regimen of pain management, physiotheraphy, exercise, and psychotheraphy is often recommended. surgical treatment seem to offer only short-term relief. last updated: 9/18/2015
MalaCards based summary: Arachnoiditis, also known as adhesive arachnoiditis, is related to aseptic meningitis and arachnoid cysts, and has symptoms including paresthesia, arthralgia and muscle weakness. An important gene associated with Arachnoiditis is NEXN (Nexilin F-Actin Binding Protein). Affiliated tissues include spinal cord, brain and bone.
NINDS:46 Arachnoiditis describes a pain disorder caused by the inflammation of the arachnoid, one of the membranes that surround and protect the nerves of the spinal cord.
Wikipedia:68 Arachnoiditis is an inflammatory condition of the arachnoid mater or \'arachnoid\', one of the membranes... more...
Symptoms:51 (show all 16)
HPO human phenotypes related to Arachnoiditis:(show all 14)
UMLS symptoms related to Arachnoiditis:agitation postoperative
Drugs for Arachnoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 25)
Interventional clinical trials:
Search NIH Clinical Center for Arachnoiditis
MalaCards organs/tissues related to Arachnoiditis:33
Spinal cord, Brain, Bone, Heart, Lung, T cells, Eye
Articles related to Arachnoiditis:(show top 50) (show all 1131)
Search GEO for disease gene expression data for Arachnoiditis.
28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet