IIAC
MCID: ART035
MIFTS: 25

Arterial Calcification of Infancy (IIAC) malady

Summaries for Arterial Calcification of Infancy

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33MalaCards
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MalaCards: Arterial Calcification of Infancy, also known as generalized arterial calcification in infancy, is related to pseudoxanthoma elasticum and generalized arterial calcification of infancy. An important gene associated with Arterial Calcification of Infancy is ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). The compounds metformin and hydroxyapatite have been mentioned in the context of this disorder. Related mouse phenotypes are other and renal/urinary system.

Aliases & Classifications for Arterial Calcification of Infancy

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43NIH Rare Diseases, 20GeneTests, 22GTR, 10DISEASES
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Aliases & Descriptions:

arterial calcification of infancy 43 22
generalized arterial calcification in infancy 43 20
generalized arterial calcification of infancy 10
idiopathic infantile arterial calcification 43
occlusive infantile arteriopathy 43
iiac 43


Related Diseases for Arterial Calcification of Infancy

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Arterial Calcification of Infancy:



Diseases related to arterial calcification of infancy

Clinical Features for Arterial Calcification of Infancy

Drugs & Therapeutics for Arterial Calcification of Infancy

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Arterial Calcification of Infancy

Genetic Tests for Arterial Calcification of Infancy

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20GeneTests, 22GTR
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Genetic tests related to Arterial Calcification of Infancy:

id Genetic test Affiliating Genes
1 Arterial Calcification, Generalized, Of Infancy20 ENPP1
2 Arterial Calcification Of Infancy22

Anatomical Context for Arterial Calcification of Infancy

Animal Models for Arterial Calcification of Infancy or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Arterial Calcification of Infancy:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053958.9ABCC6, ENPP1, PHEX
2MP:00053678.0ACE, PHEX, FGF23, ABCC6
3MP:00053907.9PHEX, ENPP1, SLC20A2, FGF23
4MP:00053787.7FGF23, PHEX, SLC20A2, ACE, ENPP1
5MP:00053767.3SLC20A2, PHEX, FGF23, ABCC6, ACE, ENPP1

Publications for Arterial Calcification of Infancy

Genetic Variations for Arterial Calcification of Infancy

Expression for genes affiliated with Arterial Calcification of Infancy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Arterial Calcification of Infancy

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Pathways for genes affiliated with Arterial Calcification of Infancy

Compounds for genes affiliated with Arterial Calcification of Infancy

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45Novoseek, 50PharmGKB, 11DrugBank, 24HMDB
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Compounds related to Arterial Calcification of Infancy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1metformin45 50 1111.6ENPP1, ACE
2hydroxyapatite459.2ENPP1, FGF23
3phosphorus459.1FGF23, PHEX
41,25 dihydroxy vitamin d3459.0PHEX, FGF23
5sodium45 249.6PHEX, SLC20A2, ACE
6calcium45 50 11 2410.7PHEX, S100A11, FGF23, ENPP1, ACE

GO Terms for genes affiliated with Arterial Calcification of Infancy

Sources:
16Gene Ontology
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Biological processes related to Arterial Calcification of Infancy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phosphate-containing compound metabolic processGO:0067969.5ENPP1, FGF23
2cellular phosphate ion homeostasisGO:0306439.2ENPP1, FGF23

Products for genes affiliated with Arterial Calcification of Infancy

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  • Proteins
  • Lysates
  • Antibodies

Sources for Arterial Calcification of Infancy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet