IIAC
MCID: ART035
MIFTS: 26

Arterial Calcification of Infancy (IIAC) malady

Summaries for Arterial Calcification of Infancy

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32MalaCards
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MalaCards: Arterial Calcification of Infancy, also known as generalized arterial calcification in infancy, is related to generalized arterial calcification of infancy and pseudoxanthoma elasticum. An important gene associated with Arterial Calcification of Infancy is ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). The compounds metformin and hydroxyapatite have been mentioned in the context of this disorder. Related mouse phenotypes are other and renal/urinary system.

Aliases & Classifications for Arterial Calcification of Infancy

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42NIH Rare Diseases, 20GeneTests, 22GTR, 10DISEASES
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Aliases & Descriptions:

arterial calcification of infancy 42 22
generalized arterial calcification in infancy 42 20
generalized arterial calcification of infancy 10
idiopathic infantile arterial calcification 42
occlusive infantile arteriopathy 42
iiac 42


Related Diseases for Arterial Calcification of Infancy

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Arterial Calcification of Infancy:



Diseases related to arterial calcification of infancy

Clinical Features for Arterial Calcification of Infancy

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Drugs & Therapeutics for Arterial Calcification of Infancy

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Arterial Calcification of Infancy

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20GeneTests, 22GTR
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Genetic tests related to Arterial Calcification of Infancy:

id Genetic test Affiliating Genes
1 Arterial Calcification, Generalized, of Infancy20 ENPP1
2 Arterial Calcification of Infancy22

Anatomical Context for Arterial Calcification of Infancy

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Animal Models for Arterial Calcification of Infancy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Arterial Calcification of Infancy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053958.9ABCC6, ENPP1, PHEX
2MP:00053678.0ACE, PHEX, FGF23, ABCC6
3MP:00053907.9PHEX, ENPP1, SLC20A2, FGF23
4MP:00053787.7FGF23, PHEX, SLC20A2, ACE, ENPP1
5MP:00053767.3SLC20A2, PHEX, FGF23, ABCC6, ACE, ENPP1

Publications for Arterial Calcification of Infancy

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Genetic Variations for Arterial Calcification of Infancy

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Expression for genes affiliated with Arterial Calcification of Infancy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Arterial Calcification of Infancy

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Pathways for genes affiliated with Arterial Calcification of Infancy

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Compounds for genes affiliated with Arterial Calcification of Infancy

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44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB
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Compounds related to Arterial Calcification of Infancy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1metformin44 49 1111.6ENPP1, ACE
2hydroxyapatite449.2ENPP1, FGF23
3phosphorus449.1FGF23, PHEX
41,25 dihydroxy vitamin d3449.0PHEX, FGF23
5sodium44 249.6PHEX, SLC20A2, ACE
6calcium44 49 11 2410.7PHEX, S100A11, FGF23, ENPP1, ACE

GO Terms for genes affiliated with Arterial Calcification of Infancy

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16Gene Ontology
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Biological processes related to Arterial Calcification of Infancy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phosphate-containing compound metabolic processGO:0067969.5ENPP1, FGF23
2cellular phosphate ion homeostasisGO:0306439.2ENPP1, FGF23

Products for genes affiliated with Arterial Calcification of Infancy

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  • Antibodies
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Sources for Arterial Calcification of Infancy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet