MCID: ART010
MIFTS: 37

Arteriolosclerosis malady

Cardiovascular diseases category

Summaries for Arteriolosclerosis

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66Wikipedia, 34MalaCards
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Wikipedia:66 Arteriolosclerosis is a form of cardiovascular disease affecting the small arteries and arterioles. more...

MalaCards: Arteriolosclerosis is related to hypertension and glomerulosclerosis. An important gene associated with Arteriolosclerosis is CD79A (CD79a molecule, immunoglobulin-associated alpha). The compounds neopterin and mannose have been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and spleen, and related mouse phenotypes are adipose tissue and muscle.

Aliases & Classifications for Arteriolosclerosis

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 36MeSH, 41NCIt, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

arteriolosclerosis 9 11 46 63


External Ids:

Disease Ontology9 DOID:5162
MeSH36 D050379
SNOMED-CT59 17941002
NCIt41 C35543

Related Diseases for Arteriolosclerosis

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Arteriolosclerosis:



Diseases related to arteriolosclerosis

Symptoms for Arteriolosclerosis

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Drugs & Therapeutics for Arteriolosclerosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Arteriolosclerosis

Drug clinical trials:

Search ClinicalTrials for Arteriolosclerosis

Search NIH Clinical Center for Arteriolosclerosis

Search CenterWatch for Arteriolosclerosis

Genetic Tests for Arteriolosclerosis

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Anatomical Context for Arteriolosclerosis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Arteriolosclerosis:

34
Kidney, Brain, Spleen, Heart

Animal Models for Arteriolosclerosis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Arteriolosclerosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.6MPV17, ADIPOQ, C3
2MP:00053698.5C3, ADIPOQ, MPV17
3MP:00053708.4C3, ADIPOQ, MPV17
4MP:00053678.2CD79A, C3, ADIPOQ, MPV17
5MP:00053978.1CD79A, C3, ADIPOQ, MPV17
6MP:00053848.1MPV17, ADIPOQ, C3, CD79A
7MP:00053767.8MPV17, ADIPOQ, C3, CD79A

Publications for Arteriolosclerosis

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53PubMed
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Articles related to Arteriolosclerosis:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. (24271328)
2014
2
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. (24135527)
2013
3
Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis. (22739424)
2012
4
Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease. (22863782)
2012
5
Severe intra- and periventricular hemorrhage: role of arteriolosclerosis related to maternal smoke. (21744137)
2011
6
Postprandial hyperglycemia and hyperinsulinemia associated with renal arterio-arteriolosclerosis in chronic kidney disease. (20186145)
2010
7
Martorell hypertensive ischemic leg ulcer: a model of ischemic subcutaneous arteriolosclerosis. (20855694)
2010
8
Association between serum adiponectin levels and arteriolosclerosis in IgA nephropathy patients. (17443034)
2007
9
Hyaline arteriolosclerosis: new meaning for an old lesion. (12631104)
2003
10
Significance of white matter high intensity lesions as a predictor of stroke from arteriolosclerosis. (11971040)
2002
11
A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin. (11789320)
2001
12
Clinical picture of arteriolosclerosis. (11725387)
2001
13
Adverse effect of donor arteriolosclerosis on graft outcome after renal transplantation. (10809815)
2000
14
Coronary reserve and arteriolosclerosis in hypertensive heart disease. (11151783)
2000
15
Super long-term surviving two renal grafts with severe arteriolosclerosis and glomerulosclerosis. (11092352)
2000
16
Severe renal arterio-arteriolosclerosis after cocaine use. (10069205)
1999
17
Brain arteriolosclerosis and hemodynamic disturbance may induce leukoaraiosis. (10563635)
1999
18
Decrease of urine protein after treatment with probucol in patients with mild glomerulonephritis and arteriolosclerosis. (7477633)
1995
19
Spontaneous coronary arteriolosclerosis in broiler chickens. (8357921)
1993
20
Myoendothelial contacts in arteriolosclerosis. (1635004)
1992
21
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. (2043948)
1991
22
Arteriolosclerosis of the human renal allograft: morphology, origin, life history and relationship to cyclosporine therapy. (1899956)
1991
23
Significance of renal hyaline arteriolosclerosis and tubulo-interstitial change in IgA glomerulonephropathy and focal glomerular sclerosis. (3696327)
1987
24
Arteriolosclerosis in a cat. (3672816)
1987
25
The pathogenesis of hyaline arteriolosclerosis. (2420184)
1986
26
Renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3736745)
1986
27
Significance of renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3897888)
1985
28
The distribution of arteriolosclerosis along the arterioles in DOCA hypertensive rats. (6627747)
1983
29
Histophysical and histochemical investigations on muscle arterioles in hypertensive arteriolosclerosis; an interference microscopical, polarization optical and histophotometrical study. (104533)
1978
30
The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriolosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. (884912)
1977
31
Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis. (878873)
1977
32
Hyaline arteriolosclerosis in wild animals. (4194799)
1970
33
Hypertension with arteriolosclerosis in childhood: report of two cases. (6043880)
1967
34
Retinal arteriolosclerosis in age, essential hypertension, and diabetes mellitus. (5964940)
1966
35
"EXUDATIVE" LESIONS IN GLOMERULI OF CHILDREN: ? A VARIANT OF HYALINE ARTERIOLOSCLEROSIS. (14280313)
1965
36
RENAL HYALINE ARTERIOLOSCLEROSIS. AN ELECTRON MICROSCOPE STUDY. (14126659)
1964
37
CONSIDERATIONS REGARDING THE PATHOGENESIS OF ARTERIOLOSCLEROSIS IN THE PULMONARY AND SYSTEMIC VASCULAR BED. (14295713)
1964
38
A graphical method for evaluation of narrowing of the coronary arteries (coronary profile method)--with special reference to intramural arteriolosclerosis. (14481493)
1962
39
Hyaline arteriolosclerosis in the spleen: an immuno-histochemical study. (13812725)
1960
40
Hyaline arteriolosclerosis in the kidney. (13243182)
1955
41
A case of primary pulmonary arteriolosclerosis in a child. (13123795)
1953
42
The pathogenesis of hyaline arteriolosclerosis. (12981614)
1952
43
The cholesterol of hyaline arteriolosclerosis. (14943797)
1952
44
The relationship of retinal and renal arteriolosclerosis in living patients with essential hypertension. (13007745)
1952
45
Primary pulmonary arteriolosclerosis. (14943296)
1952
46
The cholesterol of hyaline arteriolosclerosis. (14846922)
1951
47
Cor pulmonale resulting from pulmonary arteriolosclerosis. (14894741)
1951
48
Arteriolosclerosis in a nine-year old child. (18858655)
1948
49
Ulcer of the leg due to arteriolosclerosis and ischemia occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers); a preliminary report. (20289811)
1947
50
Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers). (20997482)
1946

Variations for Arteriolosclerosis

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Expression for genes affiliated with Arteriolosclerosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Arteriolosclerosis

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Pathways for genes affiliated with Arteriolosclerosis

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Compounds for genes affiliated with Arteriolosclerosis

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Sources:
46Novoseek, 12DrugBank, 30IUPHAR, 25HMDB, 52PharmGKB
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Compounds related to Arteriolosclerosis according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1neopterin469.7CD79A, C3
2mannose469.5CD79A, C3
3ramipril46 1210.5CD79A, ADIPOQ
4citrate469.4CD79A, ADIPOQ
5dihydrotestosterone46 30 25 1212.4ADIPOQ, CD79A
6thyroxine46 2510.4CD79A, ADIPOQ
7glycerol 3-phosphate46 2510.3C3, ADIPOQ
82-deoxyglucose46 1210.3ADIPOQ, C3
9folate469.3ADIPOQ, CD79A
10triacylglycerol469.3C3, ADIPOQ
11tacrolimus46 52 1211.3CD79A, ADIPOQ
12ascorbic acid46 2510.2CD79A, ADIPOQ
13aspirin46 52 30 2512.1ADIPOQ, CD79A
14vitamin a46 25 1211.0C3, ADIPOQ
15glycerol46 25 1210.9CD79A, C3, ADIPOQ
16fibrinogen468.9ADIPOQ, C3, CD79A
17lactate468.9CD79A, C3, ADIPOQ
18methotrexate52 46 1210.9CD79A, ADIPOQ
19creatinine468.9ADIPOQ, C3, CD79A
20heparin46 30 25 1211.9CD79A, C3, ADIPOQ
21dexamethasone46 52 30 1211.8ADIPOQ, C3, CD79A
22estrogen468.8CD79A, C3, ADIPOQ

GO Terms for genes affiliated with Arteriolosclerosis

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17Gene Ontology
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Cellular components related to Arteriolosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5C3, ACRBP, ADIPOQ

Biological processes related to Arteriolosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of protein phosphorylationGO:0019349.0C3, ADIPOQ

Products for genes affiliated with Arteriolosclerosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Arteriolosclerosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet