MCID: ART010
MIFTS: 29

Arteriolosclerosis malady

Summaries for Arteriolosclerosis

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64Wikipedia, 33MalaCards
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Wikipedia:64 Arteriolosclerosis is a form of cardiovascular disease affecting the small arteries and arterioles. more...

MalaCards: Arteriolosclerosis is related to focal segmental glomerulosclerosis and coronary heart disease. An important gene associated with Arteriolosclerosis is CD79A (CD79a molecule, immunoglobulin-associated alpha). The compounds mycophenolate mofetil and ramipril have been mentioned in the context of this disorder. Affiliated tissues include spleen, brain and heart, and related mouse phenotypes are hematopoietic system and renal/urinary system.

Aliases & Classifications for Arteriolosclerosis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 40NCIt, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

arteriolosclerosis 8 10 45 61


External Ids:

Disease Ontology8 DOID:5162
NCIt40 C35543
SNOMED-CT57 17941002
MeSH35 D050379

Related Diseases for Arteriolosclerosis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Arteriolosclerosis:



Diseases related to arteriolosclerosis

Clinical Features for Arteriolosclerosis

Drugs & Therapeutics for Arteriolosclerosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Arteriolosclerosis

Drug clinical trials:

Search ClinicalTrials for Arteriolosclerosis

Search NIH Clinical Center for Arteriolosclerosis

Search CenterWatch for Arteriolosclerosis

Genetic Tests for Arteriolosclerosis

Anatomical Context for Arteriolosclerosis

Sources:
33MalaCards
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MalaCards organs/tissues related to Arteriolosclerosis:

33
Spleen, Brain, Heart, Kidney

Animal Models for Arteriolosclerosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Arteriolosclerosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.0CD79A, C3, LDB1, ADIPOQ, MPV17
2MP:00053677.7ADIPOQ, LDB1, C3, CD79A, MPV17

Publications for Arteriolosclerosis

Sources:
51PubMed
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Articles related to Arteriolosclerosis:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. (24271328)
2014
2
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. (24135527)
2013
3
Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis. (22739424)
2012
4
Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease. (22863782)
2012
5
Severe intra- and periventricular hemorrhage: role of arteriolosclerosis related to maternal smoke. (21744137)
2011
6
Postprandial hyperglycemia and hyperinsulinemia associated with renal arterio-arteriolosclerosis in chronic kidney disease. (20186145)
2010
7
Association between serum adiponectin levels and arteriolosclerosis in IgA nephropathy patients. (17443034)
2007
8
Hyaline arteriolosclerosis: new meaning for an old lesion. (12631104)
2003
9
Significance of white matter high intensity lesions as a predictor of stroke from arteriolosclerosis. (11971040)
2002
10
A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin. (11789320)
2001
11
Clinical picture of arteriolosclerosis. (11725387)
2001
12
Adverse effect of donor arteriolosclerosis on graft outcome after renal transplantation. (10809815)
2000
13
Coronary reserve and arteriolosclerosis in hypertensive heart disease. (11151783)
2000
14
Super long-term surviving two renal grafts with severe arteriolosclerosis and glomerulosclerosis. (11092352)
2000
15
Severe renal arterio-arteriolosclerosis after cocaine use. (10069205)
1999
16
Brain arteriolosclerosis and hemodynamic disturbance may induce leukoaraiosis. (10563635)
1999
17
Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementia. (8929154)
1996
18
Decrease of urine protein after treatment with probucol in patients with mild glomerulonephritis and arteriolosclerosis. (7477633)
1995
19
Spontaneous coronary arteriolosclerosis in broiler chickens. (8357921)
1993
20
Myoendothelial contacts in arteriolosclerosis. (1635004)
1992
21
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. (2043948)
1991
22
Arteriolosclerosis of the human renal allograft: morphology, origin, life history and relationship to cyclosporine therapy. (1899956)
1991
23
Significance of renal hyaline arteriolosclerosis and tubulo-interstitial change in IgA glomerulonephropathy and focal glomerular sclerosis. (3696327)
1987
24
Arteriolosclerosis in a cat. (3672816)
1987
25
The pathogenesis of hyaline arteriolosclerosis. (2420184)
1986
26
Renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3736745)
1986
27
Significance of renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3897888)
1985
28
The distribution of arteriolosclerosis along the arterioles in DOCA hypertensive rats. (6627747)
1983
29
Histophysical and histochemical investigations on muscle arterioles in hypertensive arteriolosclerosis; an interference microscopical, polarization optical and histophotometrical study. (104533)
1978
30
The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriolosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. (884912)
1977
31
Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis. (878873)
1977
32
Hyaline arteriolosclerosis in wild animals. (4194799)
1970
33
Hypertension with arteriolosclerosis in childhood: report of two cases. (6043880)
1967
34
Retinal arteriolosclerosis in age, essential hypertension, and diabetes mellitus. (5964940)
1966
35
"EXUDATIVE" LESIONS IN GLOMERULI OF CHILDREN: ? A VARIANT OF HYALINE ARTERIOLOSCLEROSIS. (14280313)
1965
36
RENAL HYALINE ARTERIOLOSCLEROSIS. AN ELECTRON MICROSCOPE STUDY. (14126659)
1964
37
CONSIDERATIONS REGARDING THE PATHOGENESIS OF ARTERIOLOSCLEROSIS IN THE PULMONARY AND SYSTEMIC VASCULAR BED. (14295713)
1964
38
A graphical method for evaluation of narrowing of the coronary arteries (coronary profile method)--with special reference to intramural arteriolosclerosis. (14481493)
1962
39
Hyaline arteriolosclerosis in the spleen: an immuno-histochemical study. (13812725)
1960
40
Hyaline arteriolosclerosis in the kidney. (13243182)
1955
41
A case of primary pulmonary arteriolosclerosis in a child. (13123795)
1953
42
The pathogenesis of hyaline arteriolosclerosis. (12981614)
1952
43
The cholesterol of hyaline arteriolosclerosis. (14943797)
1952
44
The relationship of retinal and renal arteriolosclerosis in living patients with essential hypertension. (13007745)
1952
45
Primary pulmonary arteriolosclerosis. (14943296)
1952
46
The cholesterol of hyaline arteriolosclerosis. (14846922)
1951
47
Cor pulmonale resulting from pulmonary arteriolosclerosis. (14894741)
1951
48
Arteriolosclerosis in a nine-year old child. (18858655)
1948
49
Ulcer of the leg due to arteriolosclerosis and ischemia occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers); a preliminary report. (20289811)
1947
50
Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers). (20997482)
1946

Genetic Variations for Arteriolosclerosis

Expression for genes affiliated with Arteriolosclerosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Arteriolosclerosis

Search GEO for disease gene expression data for Arteriolosclerosis.

Pathways for genes affiliated with Arteriolosclerosis

Compounds for genes affiliated with Arteriolosclerosis

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 24HMDB, 29IUPHAR
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Compounds related to Arteriolosclerosis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1mycophenolate mofetil45 50 1111.8CD79A, CABIN1
2ramipril45 1110.8ADIPOQ, CD79A
3glycerol 3-phosphate45 2410.5ADIPOQ, C3
4neopterin459.5C3, CD79A
52-deoxyglucose45 1110.4ADIPOQ, C3
6tacrolimus45 50 1111.4ADIPOQ, CD79A, CABIN1
7glycerol45 11 2411.2ADIPOQ, C3, CD79A
8fibrinogen459.2CD79A, C3, ADIPOQ
9lactate459.1CD79A, C3, ADIPOQ
10triacylglycerol459.0ADIPOQ, C3
11heparin45 29 11 2412.0ADIPOQ, C3, CD79A
12creatinine458.9CD79A, C3, ADIPOQ

GO Terms for genes affiliated with Arteriolosclerosis

Products for genes affiliated with Arteriolosclerosis

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Sources for Arteriolosclerosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet