MCID: ART010
MIFTS: 38

Arteriolosclerosis malady

Cardiovascular diseases category
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Summaries for Arteriolosclerosis

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Wikipedia:65 Arteriolosclerosis is a form of cardiovascular disease affecting the small arteries and arterioles. more...

MalaCards based summary: Arteriolosclerosis is related to hypertension and glomerulosclerosis. An important gene associated with Arteriolosclerosis is CD79A (CD79a molecule, immunoglobulin-associated alpha). The compounds neopterin and mannose have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and spleen, and related mouse phenotypes are adipose tissue and muscle.

Aliases & Classifications for Arteriolosclerosis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
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Arteriolosclerosis, Aliases & Descriptions:

Name: Arteriolosclerosis 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:5162
MeSH34 D050379
SNOMED-CT57 17941002
NCIt39 C35543

Related Diseases for Arteriolosclerosis

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Graphical network of the top 20 diseases related to Arteriolosclerosis:



Diseases related to arteriolosclerosis

Symptoms for Arteriolosclerosis

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Drugs & Therapeutics for Arteriolosclerosis

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Drug clinical trials:

Search ClinicalTrials for Arteriolosclerosis

Search NIH Clinical Center for Arteriolosclerosis

Genetic Tests for Arteriolosclerosis

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Anatomical Context for Arteriolosclerosis

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MalaCards organs/tissues related to Arteriolosclerosis:

32
Brain, Kidney, Spleen, Heart

Animal Models for Arteriolosclerosis or affiliated genes

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MGI Mouse Phenotypes related to Arteriolosclerosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.6MPV17, ADIPOQ, C3
2MP:00053698.5C3, ADIPOQ, MPV17
3MP:00053708.4C3, ADIPOQ, MPV17
4MP:00053678.2CD79A, C3, ADIPOQ, MPV17
5MP:00053978.1CD79A, C3, ADIPOQ, MPV17
6MP:00053848.1MPV17, ADIPOQ, C3, CD79A
7MP:00053767.8MPV17, ADIPOQ, C3, CD79A

Publications for Arteriolosclerosis

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Articles related to Arteriolosclerosis:

(show top 50)    (show all 54)
idTitleAuthorsYear
1
Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. (25289893)
2014
2
Large blood pressure variability aggravates arteriolosclerosis and cortical sclerotic changes in the kidney in hypertensive rats. (24976508)
2014
3
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. (24271328)
2014
4
C3d deposition in the media of renal arterioles is a useful marker for arteriolosclerosis in IgA nephropathy. (24480433)
2014
5
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. (24135527)
2013
6
Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis. (22739424)
2012
7
Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease. (22863782)
2012
8
Severe intra- and periventricular hemorrhage: role of arteriolosclerosis related to maternal smoke. (21744137)
2011
9
Postprandial hyperglycemia and hyperinsulinemia associated with renal arterio-arteriolosclerosis in chronic kidney disease. (20186145)
2010
10
Association between serum adiponectin levels and arteriolosclerosis in IgA nephropathy patients. (17443034)
2007
11
Hyaline arteriolosclerosis: new meaning for an old lesion. (12631104)
2003
12
A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin. (11789320)
2001
13
Clinical picture of arteriolosclerosis. (11725387)
2001
14
Adverse effect of donor arteriolosclerosis on graft outcome after renal transplantation. (10809815)
2000
15
Coronary reserve and arteriolosclerosis in hypertensive heart disease. (11151783)
2000
16
Super long-term surviving two renal grafts with severe arteriolosclerosis and glomerulosclerosis. (11092352)
2000
17
Severe renal arterio-arteriolosclerosis after cocaine use. (10069205)
1999
18
Brain arteriolosclerosis and hemodynamic disturbance may induce leukoaraiosis. (10563635)
1999
19
Decrease of urine protein after treatment with probucol in patients with mild glomerulonephritis and arteriolosclerosis. (7477633)
1995
20
Spontaneous coronary arteriolosclerosis in broiler chickens. (8357921)
1993
21
Myoendothelial contacts in arteriolosclerosis. (1635004)
1992
22
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. (2043948)
1991
23
Arteriolosclerosis of the human renal allograft: morphology, origin, life history and relationship to cyclosporine therapy. (1899956)
1991
24
Significance of renal hyaline arteriolosclerosis and tubulo-interstitial change in IgA glomerulonephropathy and focal glomerular sclerosis. (3696327)
1987
25
Arteriolosclerosis in a cat. (3672816)
1987
26
The pathogenesis of hyaline arteriolosclerosis. (2420184)
1986
27
Renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3736745)
1986
28
Significance of renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. (3897888)
1985
29
Histophysical and histochemical investigations on muscle arterioles in hypertensive arteriolosclerosis; an interference microscopical, polarization optical and histophotometrical study. (104533)
1978
30
The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriolosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. (884912)
1977
31
Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis. (878873)
1977
32
Hyaline arteriolosclerosis in wild animals. (4194799)
1970
33
Hypertension with arteriolosclerosis in childhood: report of two cases. (6043880)
1967
34
Retinal arteriolosclerosis in age, essential hypertension, and diabetes mellitus. (5964940)
1966
35
"EXUDATIVE" LESIONS IN GLOMERULI OF CHILDREN: ? A VARIANT OF HYALINE ARTERIOLOSCLEROSIS. (14280313)
1965
36
RENAL HYALINE ARTERIOLOSCLEROSIS. AN ELECTRON MICROSCOPE STUDY. (14126659)
1964
37
CONSIDERATIONS REGARDING THE PATHOGENESIS OF ARTERIOLOSCLEROSIS IN THE PULMONARY AND SYSTEMIC VASCULAR BED. (14295713)
1964
38
A graphical method for evaluation of narrowing of the coronary arteries (coronary profile method)--with special reference to intramural arteriolosclerosis. (14481493)
1962
39
Hyaline arteriolosclerosis in the spleen: an immuno-histochemical study. (13812725)
1960
40
Hyaline arteriolosclerosis in the kidney. (13243182)
1955
41
A case of primary pulmonary arteriolosclerosis in a child. (13123795)
1953
42
The pathogenesis of hyaline arteriolosclerosis. (12981614)
1952
43
The cholesterol of hyaline arteriolosclerosis. (14943797)
1952
44
The relationship of retinal and renal arteriolosclerosis in living patients with essential hypertension. (13007745)
1952
45
Primary pulmonary arteriolosclerosis. (14943296)
1952
46
The cholesterol of hyaline arteriolosclerosis. (14846922)
1951
47
Cor pulmonale resulting from pulmonary arteriolosclerosis. (14894741)
1951
48
Arteriolosclerosis in a nine-year old child. (18858655)
1948
49
Ulcer of the leg due to arteriolosclerosis and ischemia occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers); a preliminary report. (20289811)
1947
50
Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers). (20997482)
1946

Variations for Arteriolosclerosis

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Expression for genes affiliated with Arteriolosclerosis

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Expression patterns in normal tissues for genes affiliated with Arteriolosclerosis

Search GEO for disease gene expression data for Arteriolosclerosis.

Pathways for genes affiliated with Arteriolosclerosis

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Compounds for genes affiliated with Arteriolosclerosis

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Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 24HMDB, 50PharmGKB
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Compounds related to Arteriolosclerosis according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1neopterin449.7CD79A, C3
2mannose449.5CD79A, C3
3ramipril44 1110.5CD79A, ADIPOQ
4citrate449.4CD79A, ADIPOQ
5dihydrotestosterone44 28 24 1112.4ADIPOQ, CD79A
6thyroxine44 2410.4CD79A, ADIPOQ
7glycerol 3-phosphate44 2410.3C3, ADIPOQ
82-deoxyglucose44 1110.3ADIPOQ, C3
9folate449.3ADIPOQ, CD79A
10triacylglycerol449.3C3, ADIPOQ
11tacrolimus44 50 1111.3CD79A, ADIPOQ
12ascorbic acid44 2410.2CD79A, ADIPOQ
13aspirin44 50 28 2412.1ADIPOQ, CD79A
14vitamin a44 24 1111.0C3, ADIPOQ
15glycerol44 24 1110.9CD79A, C3, ADIPOQ
16fibrinogen448.9ADIPOQ, C3, CD79A
17lactate448.9CD79A, C3, ADIPOQ
18methotrexate50 44 1110.9CD79A, ADIPOQ
19creatinine448.9ADIPOQ, C3, CD79A
20heparin44 28 24 1111.9CD79A, C3, ADIPOQ
21dexamethasone44 50 28 1111.8ADIPOQ, C3, CD79A
22estrogen448.8CD79A, C3, ADIPOQ

GO Terms for genes affiliated with Arteriolosclerosis

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Cellular components related to Arteriolosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5C3, ACRBP, ADIPOQ

Biological processes related to Arteriolosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of protein phosphorylationGO:0019349.0C3, ADIPOQ

Products for genes affiliated with Arteriolosclerosis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Arteriolosclerosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet