MCID: ART010
MIFTS: 29

Arteriolosclerosis

Categories: Cardiovascular diseases

Aliases & Classifications for Arteriolosclerosis

MalaCards integrated aliases for Arteriolosclerosis:

Name: Arteriolosclerosis 12 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5162
ICD10 32 I70
MeSH 41 D050379
NCIt 46 C35543
SNOMED-CT 64 17941002
UMLS 69 C0878486

Summaries for Arteriolosclerosis

MalaCards based summary : Arteriolosclerosis is related to heart disease and acute maxillary sinusitis. An important gene associated with Arteriolosclerosis is C3 (Complement C3), and among its related pathways/superpathways is Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, kidney and heart, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : 72 Arteriolosclerosis is a form of cardiovascular disease involving hardening and loss of elasticity of... more...

Related Diseases for Arteriolosclerosis

Diseases related to Arteriolosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 heart disease 28.5 ADIPOQ C3 REN
2 acute maxillary sinusitis 10.3 C3 CD79A
3 hypersensitivity vasculitis 10.3 C3 CD79A
4 hypersensitivity reaction type iii disease 10.3 C3 CD79A
5 anemia, autoimmune hemolytic 10.3 C3 CD79A
6 autoimmune disease of blood 10.2 C3 CD79A
7 henoch-schoenlein purpura 10.2 C3 CD79A
8 chronic maxillary sinusitis 10.2 C3 CD79A
9 proliferative glomerulonephritis 10.2 C3 CD79A
10 membranoproliferative glomerulonephritis 10.2 C3 CD79A
11 cerebritis 10.1
12 invasive aspergillosis 10.1 CABIN1 CD79A
13 chronic kidney failure 10.1
14 kidney disease 10.1
15 cantu syndrome 10.0 ABCC9 TARDBP
16 aging 10.0
17 hypertensive retinopathy 10.0 ADIPOQ REN
18 hypertension, essential 9.9
19 focal segmental glomerulosclerosis 1 9.9
20 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.9
21 focal segmental glomerulosclerosis 9.9
22 ischemia 9.9
23 retinitis 9.9
24 pyelitis 9.9 CD79A REN
25 apnea, obstructive sleep 9.9 ADIPOQ REN
26 obstructive jaundice 9.8 CD79A REN
27 sleep apnea 9.8 ADIPOQ REN
28 alport syndrome, x-linked 9.8 CD79A REN
29 diabetes mellitus 9.8
30 glomerulonephritis 9.8
31 hepatitis 9.8
32 hypertensive heart disease 9.8
33 dementia 9.8
34 hyperglycemia 9.8
35 vascular dementia 9.8
36 iga glomerulonephritis 9.8 CD79A REN
37 glucose metabolism disease 9.7 ADIPOQ REN
38 arteries, anomalies of 9.7 ADIPOQ REN
39 orthostatic proteinuria 9.7 C3 CD79A REN
40 acquired metabolic disease 9.6 ADIPOQ REN
41 urinary system disease 9.5 CABIN1 CD79A REN

Graphical network of the top 20 diseases related to Arteriolosclerosis:



Diseases related to Arteriolosclerosis

Symptoms & Phenotypes for Arteriolosclerosis

MGI Mouse Phenotypes related to Arteriolosclerosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.8 REN TARDBP ABCC9 ADIPOQ C3 HTRA1
2 hematopoietic system MP:0005397 9.73 ADIPOQ C3 CABIN1 CD79A REN TARDBP
3 immune system MP:0005387 9.63 ADIPOQ C3 CABIN1 CD79A REN TARDBP
4 muscle MP:0005369 9.35 ABCC9 ADIPOQ C3 REN TARDBP
5 renal/urinary system MP:0005367 8.92 ADIPOQ C3 CD79A REN

Drugs & Therapeutics for Arteriolosclerosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pathophysiology of Martorell Hypertensive Ischemic Leg Ulcer (HYTILU) Recruiting NCT01578382

Search NIH Clinical Center for Arteriolosclerosis

Cochrane evidence based reviews: arteriolosclerosis

Genetic Tests for Arteriolosclerosis

Anatomical Context for Arteriolosclerosis

MalaCards organs/tissues related to Arteriolosclerosis:

38
Brain, Kidney, Heart, Spleen

Publications for Arteriolosclerosis

Articles related to Arteriolosclerosis:

(show top 50) (show all 63)
# Title Authors Year
1
Long-term treatment with chaethomellic acid A reduces glomerulosclerosis and arteriolosclerosis in a rat model of chronic kidney disease. ( 29032332 )
2017
2
Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism. ( 28931619 )
2017
3
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. ( 26738751 )
2016
4
Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People. ( 26768207 )
2016
5
Letter by Kawada Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People". ( 27118795 )
2016
6
Relationship Between Type of Hypertension and Renal Arteriolosclerosis in Chronic Glomerular Disease. ( 27327274 )
2016
7
Response to Letter Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People". ( 27118794 )
2016
8
Hepatic Arteriolosclerosis: A Small-vessel Complication of Diabetes and Hypertension. ( 25786083 )
2015
9
Relationship between vascular function indexes, renal arteriolosclerosis, and renal clinical outcomes in chronic kidney disease. ( 25854541 )
2015
10
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. ( 24271328 )
2014
11
C3d deposition in the media of renal arterioles is a useful marker for arteriolosclerosis in IgA nephropathy. ( 24480433 )
2014
12
Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. ( 25289893 )
2014
13
Large blood pressure variability aggravates arteriolosclerosis and cortical sclerotic changes in the kidney in hypertensive rats. ( 24976508 )
2014
14
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. ( 24135527 )
2013
15
Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis. ( 22739424 )
2012
16
Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease. ( 22863782 )
2012
17
Severe intra- and periventricular hemorrhage: role of arteriolosclerosis related to maternal smoke. ( 21744137 )
2011
18
Martorell hypertensive ischemic leg ulcer: a model of ischemic subcutaneous arteriolosclerosis. ( 20855694 )
2010
19
Postprandial hyperglycemia and hyperinsulinemia associated with renal arterio-arteriolosclerosis in chronic kidney disease. ( 20186145 )
2010
20
Association between serum adiponectin levels and arteriolosclerosis in IgA nephropathy patients. ( 17443034 )
2007
21
Hyaline arteriolosclerosis: new meaning for an old lesion. ( 12631104 )
2003
22
Significance of white matter high intensity lesions as a predictor of stroke from arteriolosclerosis. ( 11971040 )
2002
23
A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin. ( 11789320 )
2001
24
Clinical picture of arteriolosclerosis. ( 11725387 )
2001
25
Coronary reserve and arteriolosclerosis in hypertensive heart disease. ( 11151783 )
2000
26
Adverse effect of donor arteriolosclerosis on graft outcome after renal transplantation. ( 10809815 )
2000
27
Super long-term surviving two renal grafts with severe arteriolosclerosis and glomerulosclerosis. ( 11092352 )
2000
28
Brain arteriolosclerosis and hemodynamic disturbance may induce leukoaraiosis. ( 10563635 )
1999
29
Severe renal arterio-arteriolosclerosis after cocaine use. ( 10069205 )
1999
30
Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementia. ( 8929154 )
1996
31
Decrease of urine protein after treatment with probucol in patients with mild glomerulonephritis and arteriolosclerosis. ( 7477633 )
1995
32
Spontaneous coronary arteriolosclerosis in broiler chickens. ( 8357921 )
1993
33
Myoendothelial contacts in arteriolosclerosis. ( 1635004 )
1992
34
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. ( 2043948 )
1991
35
Arteriolosclerosis of the human renal allograft: morphology, origin, life history and relationship to cyclosporine therapy. ( 1899956 )
1991
36
Arteriolosclerosis in a cat. ( 3672816 )
1987
37
Significance of renal hyaline arteriolosclerosis and tubulo-interstitial change in IgA glomerulonephropathy and focal glomerular sclerosis. ( 3696327 )
1987
38
Renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. ( 3736745 )
1986
39
The pathogenesis of hyaline arteriolosclerosis. ( 2420184 )
1986
40
Significance of renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. ( 3897888 )
1985
41
The distribution of arteriolosclerosis along the arterioles in DOCA hypertensive rats. ( 6627747 )
1983
42
Histophysical and histochemical investigations on muscle arterioles in hypertensive arteriolosclerosis; an interference microscopical, polarization optical and histophotometrical study. ( 104533 )
1978
43
The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriolosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. ( 884912 )
1977
44
Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis. ( 878873 )
1977
45
Hyaline arteriolosclerosis in wild animals. ( 4194799 )
1970
46
Hypertension with arteriolosclerosis in childhood: report of two cases. ( 6043880 )
1967
47
Retinal arteriolosclerosis in age, essential hypertension, and diabetes mellitus. ( 5964940 )
1966
48
"EXUDATIVE" LESIONS IN GLOMERULI OF CHILDREN: ? A VARIANT OF HYALINE ARTERIOLOSCLEROSIS. ( 14280313 )
1965
49
CONSIDERATIONS REGARDING THE PATHOGENESIS OF ARTERIOLOSCLEROSIS IN THE PULMONARY AND SYSTEMIC VASCULAR BED. ( 14295713 )
1964
50
RENAL HYALINE ARTERIOLOSCLEROSIS. AN ELECTRON MICROSCOPE STUDY. ( 14126659 )
1964

Variations for Arteriolosclerosis

Expression for Arteriolosclerosis

Search GEO for disease gene expression data for Arteriolosclerosis.

Pathways for Arteriolosclerosis

Pathways related to Arteriolosclerosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.61 ADIPOQ CD79A

GO Terms for Arteriolosclerosis

Biological processes related to Arteriolosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to drug GO:0035690 8.96 ADIPOQ REN
2 response to drug GO:0042493 8.8 ABCC9 ADIPOQ REN

Molecular functions related to Arteriolosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 8.8 ADIPOQ C3 REN

Sources for Arteriolosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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