MCID: ART021
MIFTS: 58

Arteriosclerosis malady

Categories: Cardiovascular diseases

Aliases & Classifications for Arteriosclerosis

Aliases & Descriptions for Arteriosclerosis:

Name: Arteriosclerosis 12 52 42 14 69
Arteriosclerotic Vascular Disease Nos 12
Arteriosclerotic Vascular Disease 12
Arteriosclerosis Nos 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2349
ICD10 33 I70
MeSH 42 D001161
NCIt 47 C34398
UMLS 69 C0003850

Summaries for Arteriosclerosis

Disease Ontology : 12 An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.

MalaCards based summary : Arteriosclerosis, also known as arteriosclerotic vascular disease nos, is related to pyelonephritis and myocardial infarction, and has symptoms including angina pectoris An important gene associated with Arteriosclerosis is ICAM1 (Intercellular Adhesion Molecule 1), and among its related pathways/superpathways are Degradation of the extracellular matrix and Fluid shear stress and atherosclerosis. The drugs Aspirin and Cilostazol have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and smooth muscle, and related phenotypes are Decreased free cholesterol and cardiovascular system

Wikipedia : 71 Arteriosclerosis is the thickening, hardening and loss of elasticity of the walls of arteries. This... more...

Related Diseases for Arteriosclerosis

Diseases related to Arteriosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)
id Related Disease Score Top Affiliating Genes
1 pyelonephritis 29.6 CRP EDN1 ICAM1
2 myocardial infarction 29.6 ADIPOQ APOA1 APOB APOE CCL2 COG2
3 arteriosclerosis obliterans 12.3
4 cerebral arteriosclerosis 12.2
5 intracranial arteriosclerosis 12.0
6 monckeberg arteriosclerosis 11.9
7 atherosclerosis 11.6
8 coronary artery disease 11.2
9 ischemic heart disease 11.1
10 spinal cord infarction 10.9
11 arterial calcification of infancy 10.9
12 cerebral atherosclerosis 10.9
13 werner syndrome 10.8
14 schimke immunoosseous dysplasia 10.8
15 hyperlipidemia type 3 10.7
16 retinopathy, arteriosclerotic 10.7
17 cerebritis 10.5
18 periosteal chondrosarcoma 10.4 ICAM1 SERPINE1 VCAM1
19 perrault syndrome 10.4 ICAM1 SERPINE1 VCAM1
20 craniopharyngioma 10.4 ICAM1 SERPINE1 VCAM1
21 uterine inflammatory disease 10.4 EDN1 SERPINE1
22 neuroaxonal dystrophy 10.4 CCL2 ICAM1 SERPINE1
23 vaginal endometrial stromal tumor 10.3 ADIPOQ HGF ICAM1 VCAM1
24 cortical blindness mental retardation polydactyly 10.3 ADIPOQ CCL2 VCAM1
25 acquired angioedema 10.3 ADIPOQ PPARG
26 strawberry gallbladder 10.3 CCL2 CRP ICAM1
27 craniodiaphyseal dysplasia 10.3 APOA1 APOB SERPINE1
28 xerophthalmia 10.3 CRP ICAM1 SERPINE1 VCAM1
29 epidermolysis bullosa simplex, sutosomal recessive 2 10.3 CCL2 HGF ICAM1 VCAM1
30 benign secondary hypertension 10.3 CCL2 ICAM1 SERPINE1 VCAM1
31 deafness, autosomal recessive 79 10.3 CRP ELN SPP1
32 citrullinemia, type ii, neonatal-onset 10.3 ICAM1 PON1 SERPINE1 VCAM1
33 pemphigus vulgaris, familial 10.3 CRP ICAM1 PON1 VCAM1
34 oppositional defiant disorder 10.3 CCL2 EDN1 HGF
35 eating disorder 10.3 CCL2 CRP ICAM1 VCAM1
36 asphyxia neonatorum 10.3 APOE PON1 SPP1
37 orofacial granulomatosis 10.3 HSPD1 ICAM1 VCAM1
38 amelogenesis imperfecta 10.3 CCL2 CRP ICAM1
39 iida kannari syndrome 10.3 ADIPOQ EDN1 PPARG
40 zap-70 deficiency 10.3 APOB APOE
41 transient retinal arterial occlusion 10.3 APOA1 APOB HMGCR
42 albinism, oculocutaneous, type v 10.3 APOA1 APOB APOE
43 hyperlucent lung 10.3 CCL2 CRP HSPD1
44 retinitis pigmentosa 51 10.3 CRP ELN HMOX1
45 malignant neoplasm of acoustic nerve 10.3 CCL2 EDN1 ICAM1 SERPINE1
46 bird fancier's lung 10.3 APOA1 APOB APOE
47 keratoconus 4 10.3 APOB APOE
48 cutaneous candidiasis 10.3 CCL2 ICAM1
49 spinocerebellar ataxia 20 10.3 APOA1 APOB HMGCR VCAM1
50 cataract 20, multiple types 10.3 ADIPOQ APOB PPARG SERPINE1

Graphical network of the top 20 diseases related to Arteriosclerosis:



Diseases related to Arteriosclerosis

Symptoms & Phenotypes for Arteriosclerosis

UMLS symptoms related to Arteriosclerosis:


angina pectoris

GenomeRNAi Phenotypes related to Arteriosclerosis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 8.92 APOA1 APOB APOE HMGCR

MGI Mouse Phenotypes related to Arteriosclerosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.33 EDN1 HGF HMOX1 ICAM1 MGP PON1
2 growth/size/body region MP:0005378 10.28 ADIPOQ APOB APOE COG2 EDN1 HGF
3 homeostasis/metabolism MP:0005376 10.27 ADIPOQ APOA1 APOB APOE COG2 CRP
4 cellular MP:0005384 10.21 APOE HGF HMOX1 HSPD1 ICAM1 PON1
5 immune system MP:0005387 10.06 ADIPOQ APOB APOE CCL2 CRP HMOX1
6 mortality/aging MP:0010768 10 ADIPOQ APOB APOE EDN1 HGF HMGCR
7 liver/biliary system MP:0005370 9.96 APOE HGF HMGCR HMOX1 PPARG SERPINE1
8 muscle MP:0005369 9.65 ADIPOQ APOB APOE EDN1 HMOX1 HSPD1
9 renal/urinary system MP:0005367 9.23 ADIPOQ APOE EDN1 HMOX1 MGP PPARG

Drugs & Therapeutics for Arteriosclerosis

Drugs for Arteriosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 844)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
2
Cilostazol Approved Phase 4,Phase 3,Phase 2,Phase 1 73963-72-1 2754
3
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-28-2 5757 53477783
4
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2 57-83-0 5994
5
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
6
Daclizumab Approved, Investigational Phase 4 152923-56-3
7
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
9
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
10
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
11
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
12
Pravastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 81093-37-0 54687
13
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
14
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2 75847-73-3 5362032 40466924
15
Enalaprilat Approved Phase 4,Phase 3,Phase 2 76420-72-9 6917719
16
Rimonabant Approved, Investigational Phase 4,Phase 3 168273-06-1, 158681-13-1 104850
17
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 79902-63-9 54454
18
Fluvastatin Approved Phase 4,Phase 3 93957-54-1 1548972
19
Ticagrelor Approved Phase 4,Phase 2,Phase 3,Phase 1 274693-27-5 9871419
20
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
21
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 33069-62-4 36314
22
Nitric Oxide Approved Phase 4,Phase 3,Phase 2 10102-43-9 145068
23
Bupivacaine Approved, Investigational Phase 4,Phase 2,Phase 3 2180-92-9, 38396-39-3 2474
24
Clonidine Approved Phase 4 4205-90-7 2803
25
Levobupivacaine Approved Phase 4 27262-47-1 92253
26
Morphine Approved, Investigational Phase 4 57-27-2 5288826
27
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
28
Tirofiban Approved Phase 4,Phase 3,Phase 1 144494-65-5 60947
29
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
30
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
31
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 1 37350-58-6, 51384-51-1 4171
32
Coal tar Approved Phase 4,Phase 1,Phase 2 8007-45-2
33
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
34
Ranolazine Approved, Investigational Phase 4,Phase 2,Phase 3 142387-99-3, 95635-55-5 56959
35
Ezetimibe Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 163222-33-1 150311
36
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 55-56-1 9552079 2713
37
Esmolol Approved Phase 4,Phase 3 103598-03-4, 81147-92-4 59768
38
Nicardipine Approved Phase 4 55985-32-5 4474
39
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
40
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-61-7 60961
41
Dipyridamole Approved Phase 4,Phase 3,Phase 2,Phase 1 58-32-2 3108
42
Regadenoson Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 313348-27-5 219024
43
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 111025-46-8 4829
44
Zinc Approved Phase 4,Phase 3,Phase 1 7440-66-6 32051 23994
45
Carvedilol Approved, Investigational Phase 4,Phase 3 72956-09-3 2585
46
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
47
Citalopram Approved Phase 4,Phase 3 59729-33-8 2771
48
Olmesartan Approved, Investigational Phase 4,Phase 3 144689-24-7, 144689-63-4 158781 130881
49
Nicorandil Approved Phase 4 65141-46-0 47528
50
Ethanol Approved Phase 4,Early Phase 1 64-17-5 702

Interventional clinical trials:

(show top 50) (show all 5000)
id Name Status NCT ID Phase
1 Sufficient Treatment of Peripheral Intervention by Cilostazol Unknown status NCT00912756 Phase 4
2 Kronos Early Estrogen Prevention Study (KEEPS) Unknown status NCT00154180 Phase 4
3 Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease Unknown status NCT01768585 Phase 4
4 The Low HDL On Six Weeks Statin Therapy (LOW) Study Unknown status NCT00238004 Phase 4
5 Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions Unknown status NCT00640744 Phase 4
6 Fibrosis in Renal Allografts Unknown status NCT00493194 Phase 4
7 Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina Unknown status NCT00131183 Phase 4
8 Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial Unknown status NCT02477371 Phase 4
9 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4
10 Does Rosuvastatin Delay Progression of Atherosclerosis in HIV Unknown status NCT01813357 Phase 4
11 Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases. Unknown status NCT00734123 Phase 4
12 Homocysteine Lowering and Atherosclerosis Reduction Trial (HART) Unknown status NCT00217178 Phase 4
13 Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients Unknown status NCT01101698 Phase 4
14 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
15 The Effect of Vitamin A on Atherosclerosis Unknown status NCT01414972 Phase 4
16 The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis Unknown status NCT00963222 Phase 4
17 The Effect of Dates on Plasma Lipids, Oxidative Stress and the Atherogenicity of Serum in Healthy Adults Unknown status NCT00750789 Phase 4
18 The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients Unknown status NCT00470808 Phase 4
19 ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion Unknown status NCT00407940 Phase 4
20 Fluvastatin AmelIorates aTHerosclerosis Study Unknown status NCT01681199 Phase 4
21 The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study Unknown status NCT01623193 Phase 4
22 Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease Unknown status NCT00917527 Phase 4
23 Relation Among Shear Stress Distribution, Stent Design, and Subsequent Vessel Healing After Drug-eluting Stent Implantation (SHEAR DES) Unknown status NCT01942044 Phase 4
24 Danshen Dropping Pill for Coronary Heart Disease Heart and Artery Structure and Function Unknown status NCT01825759 Phase 4
25 Intracoronary Stenting and Angiographic Results: ORSIRO Stents Versus Xience PRIME Stents Assessed by Optical Coherence Tomography Unknown status NCT01594736 Phase 4
26 Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing Unknown status NCT01456364 Phase 4
27 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4
28 Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography Unknown status NCT01260558 Phase 4
29 Test Safety and Efficacy of Zotarolimus- and Everolimus-Eluting Stents (ZES/EES) Assessed by Optical Coherence Tomography Unknown status NCT01230723 Phase 4
30 Paclitaxel Eluting Balloon and Conventional Balloon for In-Stent Restenosis of the Superficial Femoral Artery Unknown status NCT01083394 Phase 4
31 Test Efficacy of Biodegradable and Permanent Limus-Eluting Stents Unknown status NCT01068106 Phase 4
32 Global Vascular Effects of Intermittent Pneumatic Compression-Pilot Study Unknown status NCT01064323 Phase 4
33 Efficacy Study of Stenting, Paclitaxel Eluting Balloon or Atherectomy to Treat Peripheral Artery Disease Unknown status NCT00986752 Phase 4
34 Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream Unknown status NCT01785693 Phase 4
35 A Multicenter, Therapeutic Used Study to Evaluate the Efficacy and Safety of Pletaal SR Capsule (Cilostazol) in Subjects With Peripheral Arterial Disease Symptom Due to Chronic Occlusive Arterial Disease Unknown status NCT01711333 Phase 4
36 Residual Platelet Activity In Advanced Peripheral Artery Disease Unknown status NCT01627431 Phase 4
37 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
38 Platelets Induced Vasodilation, in Vitro and in Vivo Study Unknown status NCT00152646 Phase 4
39 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4
40 In Vitro and In Vivo Comparison Between Intravascular Ultrasound (IVUS) Systems Unknown status NCT02154295 Phase 4
41 Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa) Unknown status NCT02030054 Phase 4
42 "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- Unknown status NCT02028234 Phase 4
43 Potential Impact of Cigarette Smoking on Platelet Reactivity in Patients on Dual Antiplatelet Therapy With P2Y12 Inhibitors Unknown status NCT02026713 Phase 4
44 The Effects of Omega 3 and Vitamin E Supplementation on the Serum Antioxidant Enzymes and Gene Expressions of PGC-1a, h TERT, FOXOs and SIRTs in CAD Patients Unknown status NCT02011906 Phase 4
45 Italian Diffuse/Multivessel Disease ABSORB Prospective Registry: IT-Disappears Unknown status NCT02004730 Phase 4
46 Low-dose Statins and Nutraceuticals in High-intensity Statin-intolerant Patients Unknown status NCT02001883 Phase 4
47 Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention Unknown status NCT01968577 Phase 4
48 Efficacy and Safety of Paclitaxel-eluting Balloon for Treatment of Lesions in Native Small Coronary Arteries Unknown status NCT01903902 Phase 4
49 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4
50 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4

Search NIH Clinical Center for Arteriosclerosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: arteriosclerosis

Genetic Tests for Arteriosclerosis

Anatomical Context for Arteriosclerosis

MalaCards organs/tissues related to Arteriosclerosis:

39
Heart, Endothelial, Smooth Muscle, Kidney, T Cells, Monocytes, Bone

Publications for Arteriosclerosis

Articles related to Arteriosclerosis:

(show top 50) (show all 1016)
id Title Authors Year
1
Arteriosclerosis, Thrombosis, and Vascular Biology. ( 28062452 )
2017
2
Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" of the Italian Society of Diabetology (SID) and of the Italian Society for the Study of Arteriosclerosis (SISA). ( 27956024 )
2017
3
Emerging Novel Biomarkers for Arteriosclerosis Obliterans. ( 26632166 )
2016
4
Radiographic manifestations of MAPnckeberg arteriosclerosis in the head and neck region. ( 27051640 )
2016
5
MicroRNA-155 Promotes the Directional Migration of Resident Smooth Muscle Progenitor Cells by Regulating Monocyte Chemoattractant Protein 1 in Transplant Arteriosclerosis. ( 27079875 )
2016
6
Baseline Characterization of Japanese Peripheral Arterial Disease Patientsa88- Analysis of Surveillance of Cardiovascular Events in Antiplatelet-Treated Arteriosclerosis Obliterans Patients in Japan (SEASON). ( 26841805 )
2016
7
Arteriosclerosis in the ventral aorta and epicarditis in the bulbus arteriosus of Atlantic salmon (Salmo salar L). ( 27723105 )
2016
8
Lycopene Ameliorates Transplant Arteriosclerosis in Vascular Allograft Transplantation by Regulating the NO/cGMP Pathways and Rho-Associated Kinases Expression. ( 28050227 )
2016
9
In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients. ( 27273729 )
2016
10
Estimating the extent of subclinical arteriosclerosis of persons with prediabetes and diabetes mellitus among Japanese urban workers and their families: a cross-sectional study. ( 26911293 )
2016
11
Lipoprotein binding to anionic biopolyelectrolytes and the effect of glucose on nanoplaque formation in arteriosclerosis and Alzheimer's disease. ( 26969281 )
2016
12
TRANSPLANT ARTERIOSCLEROSIS. ( 27495767 )
2016
13
Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model. ( 26819270 )
2016
14
A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation. ( 27495763 )
2016
15
Relationship Of Visceral Fat Accumulation And Arteriosclerosis Risk In Obese Children: 3573 Board #12 June 4, 8: 00 AM - 9: 30 AM. ( 27361939 )
2016
16
Men, testosterone, and arteriosclerosis. ( 28039222 )
2016
17
A Rare Complication of Spinal Cord Ischemia Following Endovascular Aneurysm Repair of an Infrarenal Abdominal Aortic Aneurysm with Arteriosclerosis Obliterans: Report of a Case. ( 27738476 )
2016
18
Renal artery bilateral arteriosclerosis cause of resistant hypertension in hemodialysed patients. ( 27516040 )
2016
19
APOL1 Risk Alleles are Associated with More Severe Arteriosclerosis in Renal Resistance Vessels with Aging and Hypertension. ( 27610422 )
2016
20
Subclinical arteriosclerosis and osteoprotegerin levels in a population with systemic lupus erythematous in the south of Europe. ( 26768749 )
2016
21
Work-Related Psychosocial Hazards and Arteriosclerosis. ( 26549394 )
2015
22
The CHADS2 score is a useful predictor of coronary arteriosclerosis on 320 slice CT and may correlate with prognosis in subjects with atrial fibrillation. ( 25464421 )
2015
23
Investigating the Role of the Posttranscriptional Gene Regulator MiR-24- 3p in the Proliferation, Migration and Apoptosis of Human Arterial Smooth Muscle Cells in Arteriosclerosis Obliterans. ( 26159387 )
2015
24
Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study. ( 26432835 )
2015
25
The pathogenesis of arteriosclerosis. ( 27088150 )
2015
26
Arteriosclerosis: facts and fancy. ( 26365806 )
2015
27
Systemic arteriosclerosis and eating behavior in Japanese type 2 diabetic patients with visceral fat accumulation. ( 25592402 )
2015
28
Interrelationships between indices of longitudinal movement of the common carotid artery wall and the conventional measures of subclinical arteriosclerosis. ( 26373805 )
2015
29
MicroRNA-133a in the Development of Arteriosclerosis Obliterans. ( 25740337 )
2015
30
Hydrolysis of plasmalogen by phospholipase A1 from Streptomyces albidoflavus for early detection of dementia and arteriosclerosis. ( 26354853 )
2015
31
Logistic Regression Analysis of Depression in Arteriosclerosis Obliterans Patients and Its Risk Factors. ( 26564507 )
2015
32
Relationship Between Lymphedema and Arteriosclerosis: Higher Cardio-Ankle Vascular Index (CAVI) in Lymphedematous Limbs. ( 25695448 )
2015
33
Does arteriosclerosis contribute to hemifacial spasm? ( 26545931 )
2015
34
The role of high cholesterol-high fructose diet on coronary arteriosclerosis. ( 26260796 )
2015
35
Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study. ( 26539975 )
2015
36
Unrecognized arteriosclerosis is associated with wound complications after below-knee amputation. ( 25433284 )
2015
37
MAPnckeberg's arteriosclerosis: vascular calcification complicating microvascular surgery. ( 25457834 )
2015
38
Angina Pectoris and Arteriosclerosis. ( 26547477 )
2015
39
Endothelial Cell Apoptosis Induces TGF-I^ Signaling-Dependent Host Endothelial-Mesenchymal Transition to Promote Transplant Arteriosclerosis. ( 26372910 )
2015
40
Calcific MAPnckeberg's arteriosclerosis: An uncommon cause of radial access failure. ( 25577779 )
2015
41
AIP1-mediated stress signaling in atherosclerosis and arteriosclerosis. ( 25732743 )
2015
42
Correlation Between Arteriosclerosis and Periodontal Condition Assessed by Lactoferrin and I+1-Antitrypsin Levels in Gingival Crevicular Fluid. ( 26549390 )
2015
43
Endothelial progenitor cells induce transplant arteriosclerosis via VEGFR-1/2 activity. ( 25437886 )
2015
44
Beraprost Sodium Protects Against Diabetic Nephropathy in Patients with Arteriosclerosis Obliterans: A Prospective, Randomized, Open-label Study. ( 25959199 )
2015
45
Monckeberg's Arteriosclerosis in Temporal Arteritis Suspect. ( 26711297 )
2015
46
p-Cresyl sulfate is associated with carotid arteriosclerosis in hemodialysis patients and promotes atherogenesis in apoE-/- mice. ( 26466319 )
2015
47
Advanced glycation end products accelerate arteriosclerosis after renal transplantation through the AGE/RAGE/ILK pathway. ( 26210487 )
2015
48
Tadalafil attenuates graft arteriosclerosis of aortic transplant in a rat model. ( 26526520 )
2015
49
Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans. ( 26370316 )
2015
50
Non-healing ulcer of right foot due to Monckeberg's arteriosclerosis. ( 25630335 )
2015

Variations for Arteriosclerosis

Expression for Arteriosclerosis

Search GEO for disease gene expression data for Arteriosclerosis.

Pathways for Arteriosclerosis

GO Terms for Arteriosclerosis

Cellular components related to Arteriosclerosis according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 intracellular membrane-bounded organelle GO:0043231 9.99 APOB HMGCR HMOX1 HSPD1 PON1 PPARG
2 early endosome GO:0005769 9.88 APOA1 APOB APOE HSPD1 VCAM1
3 extracellular region GO:0005576 9.77 ADIPOQ APOA1 APOB APOE CCL2 CRP
4 high-density lipoprotein particle GO:0034364 9.63 APOA1 APOE PON1
5 very-low-density lipoprotein particle GO:0034361 9.61 APOA1 APOB APOE
6 endocytic vesicle lumen GO:0071682 9.54 APOA1 APOB APOE
7 low-density lipoprotein particle GO:0034362 9.5 APOA1 APOB APOE
8 extracellular space GO:0005615 9.5 ADIPOQ APOA1 APOB APOE CCL2 CRP
9 spherical high-density lipoprotein particle GO:0034366 9.49 APOA1 PON1
10 chylomicron GO:0042627 9.43 APOA1 APOB APOE
11 intermediate-density lipoprotein particle GO:0034363 9.33 APOA1 APOB APOE
12 extracellular exosome GO:0070062 10.18 ADIPOQ APOA1 APOB APOE CRP HSPD1

Biological processes related to Arteriosclerosis according to GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.98 ELN ICAM1 SERPINE1 SPP1 VCAM1
2 negative regulation of neuron apoptotic process GO:0043524 9.95 APOE CCL2 HMOX1 HSPD1
3 steroid metabolic process GO:0008202 9.92 APOA1 APOB APOE HMGCR
4 regulation of lipid metabolic process GO:0019216 9.91 APOA1 HMGCR PPARG
5 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.91 ADIPOQ HGF ICAM1
6 cellular response to insulin stimulus GO:0032869 9.91 ADIPOQ CCL2 PPARG
7 cellular response to interleukin-1 GO:0071347 9.9 CCL2 EDN1 ICAM1
8 response to organic substance GO:0010033 9.9 APOB HSPD1 PPARG SPP1
9 response to glucocorticoid GO:0051384 9.89 ADIPOQ CCL2 HSPD1
10 regulation of blood pressure GO:0008217 9.89 EDN1 HMOX1 PPARG
11 cellular response to drug GO:0035690 9.88 ADIPOQ CCL2 EDN1
12 cell chemotaxis GO:0060326 9.88 CCL2 HGF VCAM1
13 negative regulation of inflammatory response GO:0050728 9.88 ADIPOQ APOA1 APOE HGF
14 cholesterol homeostasis GO:0042632 9.87 APOA1 APOB APOE
15 retinoid metabolic process GO:0001523 9.87 APOA1 APOB APOE
16 cellular response to interferon-gamma GO:0071346 9.87 CCL2 EDN1 ICAM1
17 response to estrogen GO:0043627 9.87 APOA1 HMOX1 HSPD1 PPARG
18 positive regulation of smooth muscle cell proliferation GO:0048661 9.86 EDN1 HMGCR HMOX1
19 lipoprotein metabolic process GO:0042157 9.85 APOA1 APOB APOE
20 response to nicotine GO:0035094 9.83 EDN1 HMOX1 VCAM1
21 animal organ regeneration GO:0031100 9.83 APOA1 CCL2 HGF PPARG
22 response to ethanol GO:0045471 9.83 ADIPOQ CCL2 HMGCR ICAM1 VCAM1
23 response to amino acid GO:0043200 9.82 CCL2 EDN1 ICAM1
24 negative regulation of MAP kinase activity GO:0043407 9.81 ADIPOQ APOE HMGCR
25 cellular response to tumor necrosis factor GO:0071356 9.8 APOB CCL2 EDN1 ICAM1 VCAM1
26 response to lipopolysaccharide GO:0032496 9.8 APOB CCL2 EDN1 HSPD1 ICAM1 VCAM1
27 negative regulation of smooth muscle cell proliferation GO:0048662 9.79 ADIPOQ HMOX1 PPARG
28 triglyceride catabolic process GO:0019433 9.79 APOA1 APOB APOE
29 low-density lipoprotein particle clearance GO:0034383 9.78 ADIPOQ APOB HMOX1
30 response to activity GO:0014823 9.78 ADIPOQ CCL2 EDN1 HSPD1
31 cholesterol efflux GO:0033344 9.77 APOA1 APOB APOE
32 negative regulation of smooth muscle cell migration GO:0014912 9.74 ADIPOQ SERPINE1
33 high-density lipoprotein particle assembly GO:0034380 9.73 APOA1 APOE
34 low-density lipoprotein particle remodeling GO:0034374 9.73 APOB APOE
35 phospholipid efflux GO:0033700 9.73 APOA1 APOE
36 long-chain fatty acid transport GO:0015909 9.73 APOE PPARG
37 negative regulation of wound healing GO:0061045 9.73 HMGCR SERPINE1
38 positive regulation of cholesterol efflux GO:0010875 9.73 ADIPOQ APOE PON1
39 negative regulation of hormone secretion GO:0046888 9.72 ADIPOQ EDN1
40 maternal process involved in parturition GO:0060137 9.72 CCL2 EDN1
41 chronic inflammatory response GO:0002544 9.72 CCL2 VCAM1
42 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.72 ADIPOQ CRP PPARG
43 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.71 ADIPOQ APOA1
44 positive regulation of cholesterol esterification GO:0010873 9.71 APOA1 APOE
45 high-density lipoprotein particle clearance GO:0034384 9.71 APOA1 APOE
46 negative regulation of blood coagulation GO:0030195 9.71 APOE EDN1 SERPINE1
47 chylomicron remnant clearance GO:0034382 9.7 APOB APOE
48 lipoprotein biosynthetic process GO:0042158 9.69 APOA1 APOB APOE
49 positive regulation of cellular extravasation GO:0002693 9.68 CCL2 ICAM1
50 neuron projection regeneration GO:0031102 9.68 APOA1 APOE

Molecular functions related to Arteriosclerosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.76 ADIPOQ CCL2 EDN1 SPP1
2 phospholipid binding GO:0005543 9.46 APOA1 APOB APOE PON1
3 lipid transporter activity GO:0005319 9.43 APOA1 APOB APOE
4 high-density lipoprotein particle binding GO:0008035 9.4 APOA1 HSPD1
5 lipoprotein particle binding GO:0071813 9.37 APOA1 APOE
6 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.32 APOA1 APOE
7 cholesterol transporter activity GO:0017127 9.13 APOA1 APOB APOE
8 low-density lipoprotein particle receptor binding GO:0050750 8.8 APOB APOE CRP
9 protein binding GO:0005515 10.36 ADIPOQ APOA1 APOB APOE COG2 CRP

Sources for Arteriosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
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37 KEGG
38 LifeMap
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42 MeSH
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48 NDF-RT
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52 Novoseek
54 OMIM
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59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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