Aliases & Classifications for Arteriosclerosis

MalaCards integrated aliases for Arteriosclerosis:

Name: Arteriosclerosis 12 51 41 14 69
Arteriosclerotic Vascular Disease Nos 12
Arteriosclerotic Vascular Disease 12
Arteriosclerosis Nos 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2349
ICD10 32 I70
MeSH 41 D001161
NCIt 46 C34398
UMLS 69 C0003850

Summaries for Arteriosclerosis

Disease Ontology : 12 An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.

MalaCards based summary : Arteriosclerosis, also known as arteriosclerotic vascular disease nos, is related to arteriosclerosis obliterans and ischemic heart disease, and has symptoms including angina pectoris An important gene associated with Arteriosclerosis is APOB (Apolipoprotein B), and among its related pathways/superpathways are Degradation of the extracellular matrix and G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins. The drugs Aspirin and Cilostazol have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and testes, and related phenotypes are Decreased free cholesterol and cardiovascular system

Wikipedia : 72 Arteriosclerosis is the thickening, hardening and loss of elasticity of the walls of arteries. This... more...

Related Diseases for Arteriosclerosis

Diseases in the Arteriosclerosis family:

Arteriosclerosis, Severe Juvenile

Diseases related to Arteriosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 arteriosclerosis obliterans 34.3 ADIPOQ HGF ICAM1 VCAM1
2 ischemic heart disease 32.5 APOA1 APOB APOE CCL2 CRP
3 hyperlipoproteinemia, type iii 31.6 APOA1 APOB APOE COG2 HMGCR
4 coronary artery anomaly 31.5 ADIPOQ APOA1 APOB APOE COG2 CRP
5 coronary heart disease 1 31.0 ADIPOQ APOA1 APOB APOE COG2 CRP
6 aging 30.8 EDN1 ICAM1 PPARG SERPINE1
7 ischemia 30.6 EDN1 HMOX1 ICAM1 PON1
8 vasculitis 30.4 CCL2 CRP ICAM1 VCAM1
9 aortic aneurysm, familial abdominal, 1 30.3 APOE CCL2 CRP ELN
10 peripheral artery disease 30.3 APOB CCL2 CRP VCAM1
11 endocarditis 30.3 CRP HSPD1 VCAM1
12 chronic kidney failure 30.2 CRP EDN1 HMGCR ICAM1 VCAM1
13 apnea, obstructive sleep 30.2 ADIPOQ CRP EDN1
14 chronic venous insufficiency 30.2 ICAM1 SERPINE1 VCAM1
15 takayasu arteritis 30.2 CRP PON1 VCAM1
16 wrinkles 30.2 ELN HGF
17 venous insufficiency 30.1 CRP ICAM1 SERPINE1 VCAM1
18 hypertension, essential 30.0 ADIPOQ APOA1 APOB CRP EDN1 PON1
19 atherosclerosis susceptibility 30.0 ADIPOQ APOA1 APOB APOE CCL2 COG2
20 peripheral vascular disease 30.0 APOA1 APOB CRP SERPINE1 VCAM1
21 pulmonary edema 29.9 CRP EDN1 HMOX1 ICAM1
22 arcus corneae 29.9 APOA1 APOB APOE COG2
23 heart disease 29.9 ADIPOQ APOB APOE CRP EDN1 ELN
24 sleep apnea 29.8 ADIPOQ APOE CRP EDN1 ICAM1
25 stroke, ischemic 29.7 APOB APOE COG2 CRP HMGCR SERPINE1
26 hypercholesterolemia, familial 29.4 APOA1 APOB APOE COG2 CRP HMGCR
27 myocardial infarction 29.4 ADIPOQ APOA1 APOB APOE CCL2 COG2
28 body mass index quantitative trait locus 11 29.2 ADIPOQ APOA1 APOB APOE CCL2 COG2
29 arteries, anomalies of 29.0 ADIPOQ APOA1 APOB APOE CCL2 COG2
30 diabetes mellitus, noninsulin-dependent 28.5 ADIPOQ APOA1 APOB APOE CCL2 COG2
31 vascular disease 28.3 ADIPOQ APOA1 APOB APOE CCL2 CRP
32 cerebral arteriosclerosis 12.4
33 monckeberg arteriosclerosis 12.0
34 intracranial arteriosclerosis 11.9
35 arteriosclerosis, severe juvenile 11.8
36 spinal cord infarction 11.1
37 arterial calcification of infancy 11.0
38 cerebral atherosclerosis 11.0
39 schimke immunoosseous dysplasia 10.9
40 werner syndrome 10.9
41 retinopathy, arteriosclerotic 10.8
42 malignant renovascular hypertension 10.7 EDN1 SERPINE1
43 coronary artery aneurysm 10.6 ADIPOQ CCL2 VCAM1
44 dysbaric osteonecrosis 10.6 APOA1 APOB SERPINE1
45 subendocardial myocardial infarction 10.6 ICAM1 SERPINE1 VCAM1
46 post-thrombotic syndrome 10.6 CCL2 ICAM1 SERPINE1
47 cerebritis 10.6
48 shwartzman phenomenon 10.6 ICAM1 SERPINE1 VCAM1
49 abdominal obesity-metabolic syndrome 1 10.6 ADIPOQ PPARG SERPINE1
50 autoimmune myocarditis 10.6 PPARG SPP1 VCAM1

Graphical network of the top 20 diseases related to Arteriosclerosis:



Diseases related to Arteriosclerosis

Symptoms & Phenotypes for Arteriosclerosis

UMLS symptoms related to Arteriosclerosis:


angina pectoris

GenomeRNAi Phenotypes related to Arteriosclerosis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 8.92 APOA1 APOB APOE HMGCR

MGI Mouse Phenotypes related to Arteriosclerosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.33 SERPINE1 ICAM1 SPP1 MGP VCAM1 PON1
2 growth/size/body region MP:0005378 10.28 HSPD1 SERPINE1 ICAM1 SPP1 MGP VCAM1
3 homeostasis/metabolism MP:0005376 10.27 SERPINE1 ICAM1 SPP1 MGP VCAM1 PON1
4 cellular MP:0005384 10.21 PPARG HSPD1 ICAM1 SPP1 PON1 VCAM1
5 immune system MP:0005387 10.06 HMOX1 PPARG SERPINE1 ICAM1 SPP1 VCAM1
6 mortality/aging MP:0010768 10 HSPD1 SERPINE1 ICAM1 SPP1 MGP VCAM1
7 liver/biliary system MP:0005370 9.96 SERPINE1 SPP1 PPARG HGF APOB HMGCR
8 muscle MP:0005369 9.65 HSPD1 ICAM1 SPP1 MGP PPARG APOB
9 renal/urinary system MP:0005367 9.23 HMOX1 PPARG SERPINE1 SPP1 MGP APOE

Drugs & Therapeutics for Arteriosclerosis

Drugs for Arteriosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 873)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
2
Cilostazol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 73963-72-1 2754
3
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-28-2 5757
4
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2 57-83-0 5994
5
Chromium Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-47-3 27668
6
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
8
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 46835353 6436030 5284616
9
Daclizumab Approved, Investigational Phase 4 152923-56-3
10
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
11
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
12
Pravastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 81093-37-0 54687
13
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
14
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120202-66-6, 113665-84-2 60606
15
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2 75847-73-3 40466924 5362032
16
Enalaprilat Approved Phase 4,Phase 3,Phase 2 76420-72-9 6917719
17
Rimonabant Approved, Investigational Phase 4,Phase 3 168273-06-1, 158681-13-1 104850
18
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 79902-63-9 54454
19
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 5460373 44475014 11953898
20
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 33069-62-4 36314
21
Fluvastatin Approved Phase 4,Phase 3 93957-54-1 1548972
22
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Early Phase 1 76631-46-4, 113775-47-6 5311068 56032 68602
23
Etomidate Approved Phase 4 33125-97-2 667484 36339
24
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
25
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
26
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
27
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
28
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-61-7 60961
29
Menthol Approved Phase 4,Phase 3,Phase 2,Early Phase 1 2216-51-5 16666
30
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
31
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
32
Thrombin Approved, Investigational Phase 4,Phase 2,Phase 3
33
Vorapaxar Approved Phase 4,Phase 3,Phase 2 618385-01-6
34
Ezetimibe Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 163222-33-1 150311
35
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 46507594 772
36
Tirofiban Approved Phase 4,Phase 3,Phase 1 144494-65-5 60947
37
Trimetazidine Approved, Investigational Phase 4 5011-34-7
38
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
39
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
40
Lovastatin Approved, Investigational Phase 4,Phase 3,Phase 2 75330-75-5 53232
41
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 1 51384-51-1, 37350-58-6 4171
42
Pitavastatin Approved Phase 4,Phase 3 147511-69-1, 147526-32-7 5282452 6366718
43
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
44
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 95635-55-5, 142387-99-3 56959
45
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 55-56-1 2713 9552079
46
Esmolol Approved Phase 4,Phase 3 81147-92-4, 103598-03-4 59768
47
Nicardipine Approved, Investigational Phase 4,Early Phase 1 55985-32-5 4474
48
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
49
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2 38396-39-3, 2180-92-9 2474
50
Clonidine Approved Phase 4 4205-90-7 2803

Interventional clinical trials:

(show top 50) (show all 5573)

# Name Status NCT ID Phase Drugs
1 Sufficient Treatment of Peripheral Intervention by Cilostazol Unknown status NCT00912756 Phase 4 cilostazol
2 Kronos Early Estrogen Prevention Study (KEEPS) Unknown status NCT00154180 Phase 4 Conjugated equine estrogens 0.45 mg/day;Transdermal estradiol, 50 mcg/day;Micronized progesterone, 200 mg/day x 12 d/month;CEE , progesterone, estradiol patch or placebo for each;CEE, progesterone, transdermal patch or the placebo
3 Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease Unknown status NCT01768585 Phase 4 Ivabradine;Placebo
4 BioMime Vs. Xience Randomised Control Clinical Study Unknown status NCT02112981 Phase 4
5 The Low HDL On Six Weeks Statin Therapy (LOW) Study Unknown status NCT00238004 Phase 4 Nicotinic acid
6 Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions Unknown status NCT00640744 Phase 4 Atorvastatin
7 Fibrosis in Renal Allografts Unknown status NCT00493194 Phase 4 sirolimus;cyclosporine;daclizumab
8 Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina Unknown status NCT00131183 Phase 4 Nebido
9 Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial Unknown status NCT02477371 Phase 4
10 The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris Unknown status NCT01325818 Phase 4 pravastatin, rosuvastatin
11 Does Rosuvastatin Delay Progression of Atherosclerosis in HIV Unknown status NCT01813357 Phase 4 Rosuvastatin
12 Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases. Unknown status NCT00734123 Phase 4 Simvastatin or Atorvastatin;Enalapril;Aspirin or clopidogrel;Rimonabant
13 Homocysteine Lowering and Atherosclerosis Reduction Trial (HART) Unknown status NCT00217178 Phase 4 Vitamins: Folic acid, B6, B12
14 Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients Unknown status NCT01101698 Phase 4 Vitamin K2+10μg cholecalciferol;Vitamin D
15 Paclitaxel Eluting Stent or Exercise for Thigh Atherosclerosis Unknown status NCT02033135 Phase 4
16 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
17 The Effect of Vitamin A on Atherosclerosis Unknown status NCT01414972 Phase 4 Vitamin A;placebo
18 The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis Unknown status NCT00963222 Phase 4 vitamin A;placebo
19 The Effect of Dates on Plasma Lipids, Oxidative Stress and the Atherogenicity of Serum in Healthy Adults Unknown status NCT00750789 Phase 4
20 Fluvastatin AmelIorates aTHerosclerosis Study Unknown status NCT01681199 Phase 4 Fluvastatin extended release tablet
21 The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study Unknown status NCT01623193 Phase 4
22 Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG Unknown status NCT02727712 Phase 4 Anesthesia drugs during the surgery
23 The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients Unknown status NCT00470808 Phase 4 POMx
24 ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion Unknown status NCT00407940 Phase 4
25 Relation Among Shear Stress Distribution, Stent Design, and Subsequent Vessel Healing After Drug-eluting Stent Implantation (SHEAR DES) Unknown status NCT01942044 Phase 4
26 Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease Unknown status NCT00917527 Phase 4 Atorvastatin
27 Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Tria Unknown status NCT01918111 Phase 4 adenosine infusion treatment
28 Danshen Dropping Pill for Coronary Heart Disease Heart and Artery Structure and Function Unknown status NCT01825759 Phase 4 danshen dripping pill
29 Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease-2 Unknown status NCT01664858 Phase 4
30 Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing Unknown status NCT01456364 Phase 4 Ticagrelor;Prasugrel
31 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4 Triple anti-platelet therapy (TAT);Double-dose clopidogrel anti-platelet therapy (DDAT)
32 Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography Unknown status NCT01260558 Phase 4
33 Test Safety and Efficacy of Zotarolimus- and Everolimus-Eluting Stents (ZES/EES) Assessed by Optical Coherence Tomography Unknown status NCT01230723 Phase 4
34 Paclitaxel Eluting Balloon and Conventional Balloon for In-Stent Restenosis of the Superficial Femoral Artery Unknown status NCT01083394 Phase 4
35 Test Efficacy of Biodegradable and Permanent Limus-Eluting Stents Unknown status NCT01068106 Phase 4
36 Efficacy Study of Stenting, Paclitaxel Eluting Balloon or Atherectomy to Treat Peripheral Artery Disease Unknown status NCT00986752 Phase 4
37 A Multicenter, Therapeutic Used Study to Evaluate the Efficacy and Safety of Pletaal SR Capsule (Cilostazol) in Subjects With Peripheral Arterial Disease Symptom Due to Chronic Occlusive Arterial Disease Unknown status NCT01711333 Phase 4 Pletaal SR capsule
38 Residual Platelet Activity In Advanced Peripheral Artery Disease Unknown status NCT01627431 Phase 4 Acetylsalicylic acid;Clopidogrel
39 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
40 Influence of Vorapaxar on Thrombin Generation and Coagulability Unknown status NCT02629367 Phase 4 Vorapaxar;Asprin;Clopidogrel
41 Ezetimibe and Atorvastatin Therapy on TCFA Unknown status NCT02588235 Phase 4 Ezetimibe and Atorvastatin;Atorvastatin
42 Safety and Efficacy of Low-dose Ticagrelor in Chinese Patients With Stable Coronary Artery Disease Unknown status NCT02514642 Phase 4 low-dose ticagrelor;Clopidogrel
43 Plasma and Platelet microRNAs in Clopidogrel Low Response Patients Unknown status NCT02447809 Phase 4 Clopidogrel;acetylsalicylic acid (ASA)
44 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4 tirofiban
45 Effect of Cilostazol on Endothelial Progenitor Cells and Endothelial Function in Coronary Artery Disease Unknown status NCT02174939 Phase 4 Cilostazol;Dummy Placebo
46 In Vitro and In Vivo Comparison Between Intravascular Ultrasound (IVUS) Systems Unknown status NCT02154295 Phase 4
47 The ImPact of Trimetazidine on MicrOcirculation After Stenting for Stable Coronary Artery Disease Unknown status NCT02107144 Phase 4 trimetazidine
48 Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa) Unknown status NCT02030054 Phase 4 Atorvastatin;Rosuvastatin
49 "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- Unknown status NCT02028234 Phase 4 Pantoprazole,;Omeprazole
50 Potential Impact of Cigarette Smoking on Platelet Reactivity in Patients on Dual Antiplatelet Therapy With P2Y12 Inhibitors Unknown status NCT02026713 Phase 4

Search NIH Clinical Center for Arteriosclerosis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: arteriosclerosis

Genetic Tests for Arteriosclerosis

Anatomical Context for Arteriosclerosis

MalaCards organs/tissues related to Arteriosclerosis:

38
Heart, Endothelial, Testes, Bone, Kidney, Bone Marrow, Monocytes

Publications for Arteriosclerosis

Articles related to Arteriosclerosis:

(show top 50) (show all 1049)
# Title Authors Year
1
MicroRNA-31 promotes arterial smooth muscle cell proliferation and migration by targeting mitofusin-2 in arteriosclerosis obliterans of the lower extremitie. ( 29403548 )
2018
2
Accelerated atheromatosis and arteriosclerosis in primary systemic vasculitides: current evidence and future perspectives. ( 29040156 )
2018
3
Pulsatile flow of non-Newtonian blood fluid inside stenosed arteries: Investigating the effects of viscoelastic and elastic walls, arteriosclerosis, and polycythemia diseases. ( 29249336 )
2018
4
Arteriosclerosis, Thrombosis, and Vascular Biology. ( 29282242 )
2018
5
Assessment of Subtle Changes in Diabetes-Associated Arteriosclerosis using Photoplethysmographic Pulse Wave from Index Finger. ( 29368039 )
2018
6
Spontaneously occurring intramural coronary arteriosclerosis in regularly slaughtered veal calves and beef cattle: aA screening study about prevalence and histopathological features. ( 29371083 )
2018
7
Systemic arteriosclerosis is associated with left ventricular remodeling but not atherosclerosis: a TASCFORCE study. ( 29382349 )
2018
8
Arteriosclerosis Is a Major Predictor of Small Bowel Vascular Lesions. ( 29372478 )
2018
9
Clipping treatment of posterior communicating artery aneurysms associated with arteriosclerosis and calcification: A single center study of 136 cases. ( 29434749 )
2018
10
Retinal vessel narrowing: an early predictor of future arteriosclerosis? ( 29384985 )
2018
11
Potential Effects of Desalinated Seawater on Arteriosclerosis in Rats. ( 29122097 )
2017
12
Role of TLR4 and miR-155 in peripheral blood mononuclear cell-mediated inflammatory reaction in coronary slow flow and coronary arteriosclerosis patients. ( 28407320 )
2017
13
The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. ( 28569748 )
2017
14
Association of arteriosclerosis and/or atherosclerosis with hypertensive target organ damage in the community-dwelling elderly Chinese: the Northern Shanghai Study. ( 28652715 )
2017
15
Arteriosclerosis, Thrombosis, and Vascular Biology. ( 28062452 )
2017
16
Decalogue of the Spanish Society of Arteriosclerosis to reduce therapeutic inertia. ( 28844490 )
2017
17
Blood pressure, heart rate, and double product in a pooled cohort: the Japan Arteriosclerosis Longitudinal Study. ( 28486272 )
2017
18
Mice, vaccine, and human arteriosclerosis. ( 29145664 )
2017
19
Consensus document on the management of the atherogenic dyslipidaemia of the Spanish Society of Arteriosclerosis. ( 28185675 )
2017
20
Efficacy of continuous positive airway pressure treatment in treating obstructive sleep apnea hypopnea syndrome associated with carotid arteriosclerosis. ( 29285176 )
2017
21
Sarcopenia and physical function are associated with inflammation and arteriosclerosis in community-dwelling people: The Yakumo study. ( 28741974 )
2017
22
Commonalities Between Vasculature and Bone: An Osseocentric View of Arteriosclerosis. ( 28115412 )
2017
23
Monckeberg Arteriosclerosis: AA TelltaleA Sign. ( 28499804 )
2017
24
Effect of sirolimus on arteriosclerosis induced by advanced glycation end products via inhibition of the ILK/mTOR pathway in kidney transplantation recipients. ( 28669853 )
2017
25
Difference in bilateral digital volume pulse as a novel non-invasive approach to assessing arteriosclerosis in aged and diabetic subjects: A preliminary study. ( 28467197 )
2017
26
Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" of the Italian Society of Diabetology (SID) and of the Italian Society for the Study of Arteriosclerosis (SISA). ( 27956024 )
2017
27
WITHDRAWN: What exactly, regression of atherosclerosis or foreign body reaction with hyaline arteriosclerosis, drives transient scaffolding of coronary arteries? A pooled analysis of observational ABSORB studies with a serial multimodality imaging substudy of ABSORB cohort B1 trial. ( 28629625 )
2017
28
The Association between Polymorphism of CARD8 rs2043211 and Susceptibility to Arteriosclerosis Obliterans in Chinese Han Male Population. ( 28135700 )
2017
29
Diffuse Carotid Arteriosclerosis and Stroke in a Patient With Schimke Immuno-osseous Dysplasia. ( 28412018 )
2017
30
Vaccine against arteriosclerosis: an update. ( 28515939 )
2017
31
The role of sildenafil in the development of transplant arteriosclerosis in rat aortic grafts. ( 29218089 )
2017
32
Intima-Media Thickness in the Carotid and Femoral Arteries for Detection of Arteriosclerosis in Human Immunodeficiency Virus-Positive Individuals. ( 28146208 )
2017
33
National Dyslipidemia Registry of the Spanish Arteriosclerosis Society: Current status. ( 29102473 )
2017
34
Mir-22-3p Inhibits Arterial Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia by Targeting HMGB1 in Arteriosclerosis Obliterans. ( 28848136 )
2017
35
Subclinical arteriosclerosis and osteoprotegerin levels in a population with systemic lupus erythematous in the south of Europe. ( 26768749 )
2016
36
Arteriosclerosis in the ventral aorta and epicarditis in the bulbus arteriosus of Atlantic salmon (Salmo salar L). ( 27723105 )
2016
37
Lipoprotein binding to anionic biopolyelectrolytes and the effect of glucose on nanoplaque formation in arteriosclerosis and Alzheimer's disease. ( 26969281 )
2016
38
Baseline Characterization of Japanese Peripheral Arterial Disease Patientsa88- Analysis of Surveillance of Cardiovascular Events in Antiplatelet-Treated Arteriosclerosis Obliterans Patients in Japan (SEASON). ( 26841805 )
2016
39
In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients. ( 27273729 )
2016
40
Renal artery bilateral arteriosclerosis cause of resistant hypertension in hemodialysed patients. ( 27516040 )
2016
41
Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model. ( 26819270 )
2016
42
A Rare Complication of Spinal Cord Ischemia Following Endovascular Aneurysm Repair of an Infrarenal Abdominal Aortic Aneurysm with Arteriosclerosis Obliterans: Report of a Case. ( 27738476 )
2016
43
Relationship Of Visceral Fat Accumulation And Arteriosclerosis Risk In Obese Children: 3573 Board #12 June 4, 8: 00 AM - 9: 30 AM. ( 27361939 )
2016
44
Emerging Novel Biomarkers for Arteriosclerosis Obliterans. ( 26632166 )
2016
45
Men, testosterone, and arteriosclerosis. ( 28039222 )
2016
46
Estimating the extent of subclinical arteriosclerosis of persons with prediabetes and diabetes mellitus among Japanese urban workers and their families: a cross-sectional study. ( 26911293 )
2016
47
MicroRNA-155 Promotes the Directional Migration of Resident Smooth Muscle Progenitor Cells by Regulating Monocyte Chemoattractant Protein 1 in Transplant Arteriosclerosis. ( 27079875 )
2016
48
TRANSPLANT ARTERIOSCLEROSIS. ( 27495767 )
2016
49
A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation. ( 27495763 )
2016
50
Lycopene Ameliorates Transplant Arteriosclerosis in Vascular Allograft Transplantation by Regulating the NO/cGMP Pathways and Rho-Associated Kinases Expression. ( 28050227 )
2016

Variations for Arteriosclerosis

Expression for Arteriosclerosis

Search GEO for disease gene expression data for Arteriosclerosis.

Pathways for Arteriosclerosis

Pathways related to Arteriosclerosis according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.59 ELN ICAM1 SERPINE1 SPP1 VCAM1
2
Show member pathways
12.06 CCL2 ELN ICAM1 SPP1 VCAM1
3 11.91 CCL2 EDN1 HMOX1 ICAM1 VCAM1
4
Show member pathways
11.85 APOA1 APOB APOE HMGCR
5
Show member pathways
11.83 APOA1 APOB APOE CCL2 CRP ICAM1
6 11.79 CCL2 EDN1 ICAM1 VCAM1
7 11.72 ADIPOQ PPARG SPP1 VCAM1
8 11.71 CCL2 HGF HMOX1 ICAM1 VCAM1
9 11.69 CCL2 HGF HMOX1
10 11.58 ADIPOQ APOA1 PPARG
11 11.55 CCL2 EDN1 ICAM1 SERPINE1 VCAM1
12 11.51 EDN1 HMOX1 SERPINE1
13 11.31 CCL2 HGF ICAM1 VCAM1
14 11.23 APOA1 ICAM1 VCAM1
15 11.2 CCL2 HMOX1 MGP
16 10.9 CCL2 EDN1 ELN HGF HMOX1 SPP1
17 10.78 CCL2 ICAM1 VCAM1

GO Terms for Arteriosclerosis

Cellular components related to Arteriosclerosis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 early endosome GO:0005769 9.89 APOA1 APOB APOE HSPD1 VCAM1
2 extracellular region GO:0005576 9.77 ADIPOQ APOA1 APOB APOE CCL2 CRP
3 extracellular matrix GO:0031012 9.7 APOA1 APOE ELN HSPD1 ICAM1 MGP
4 high-density lipoprotein particle GO:0034364 9.65 APOA1 APOE PON1
5 very-low-density lipoprotein particle GO:0034361 9.63 APOA1 APOB APOE
6 endocytic vesicle lumen GO:0071682 9.58 APOA1 APOB APOE
7 low-density lipoprotein particle GO:0034362 9.54 APOA1 APOB APOE
8 spherical high-density lipoprotein particle GO:0034366 9.52 APOA1 PON1
9 discoidal high-density lipoprotein particle GO:0034365 9.51 APOA1 APOE
10 chylomicron GO:0042627 9.5 APOA1 APOB APOE
11 extracellular space GO:0005615 9.5 ADIPOQ APOA1 APOB APOE CCL2 CRP
12 intermediate-density lipoprotein particle GO:0034363 9.43 APOA1 APOB APOE
13 extracellular exosome GO:0070062 10.21 ADIPOQ APOA1 APOB APOE CRP HSPD1
14 intracellular membrane-bounded organelle GO:0043231 10.01 APOB HMGCR HMOX1 HSPD1 PON1 PPARG

Biological processes related to Arteriosclerosis according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.97 APOB EDN1 ICAM1 VCAM1
2 extracellular matrix organization GO:0030198 9.92 ELN ICAM1 SERPINE1 SPP1 VCAM1
3 response to organic substance GO:0010033 9.9 APOB PPARG SPP1
4 cellular response to interferon-gamma GO:0071346 9.9 CCL2 EDN1 ICAM1
5 regulation of lipid metabolic process GO:0019216 9.9 APOA1 HMGCR PPARG
6 steroid metabolic process GO:0008202 9.9 APOA1 APOB APOE HMGCR
7 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.89 ADIPOQ HGF ICAM1
8 response to ethanol GO:0045471 9.89 ADIPOQ HMGCR ICAM1 VCAM1
9 cellular response to interleukin-1 GO:0071347 9.88 CCL2 EDN1 ICAM1
10 response to hypoxia GO:0001666 9.88 ADIPOQ EDN1 HMOX1 ICAM1 VCAM1
11 cell chemotaxis GO:0060326 9.87 CCL2 HGF VCAM1
12 regulation of blood pressure GO:0008217 9.86 EDN1 HMOX1 PPARG
13 cholesterol homeostasis GO:0042632 9.86 APOA1 APOB APOE
14 response to estrogen GO:0043627 9.86 APOA1 HMOX1 PPARG
15 retinoid metabolic process GO:0001523 9.85 APOA1 APOB APOE
16 positive regulation of smooth muscle cell proliferation GO:0048661 9.84 EDN1 HMGCR HMOX1
17 negative regulation of inflammatory response GO:0050728 9.84 ADIPOQ APOA1 APOE HGF
18 animal organ regeneration GO:0031100 9.82 APOA1 HGF PPARG
19 negative regulation of MAP kinase activity GO:0043407 9.8 ADIPOQ APOE HMGCR
20 response to nicotine GO:0035094 9.8 EDN1 HMOX1 VCAM1
21 negative regulation of smooth muscle cell proliferation GO:0048662 9.78 ADIPOQ HMOX1 PPARG
22 cellular response to tumor necrosis factor GO:0071356 9.77 APOB CCL2 EDN1 ICAM1 VCAM1
23 triglyceride catabolic process GO:0019433 9.75 APOA1 APOB APOE
24 lipoprotein metabolic process GO:0042157 9.74 APOA1 APOB APOE
25 negative regulation of wound healing GO:0061045 9.73 HMGCR SERPINE1
26 negative regulation of smooth muscle cell migration GO:0014912 9.73 ADIPOQ SERPINE1
27 cholesterol efflux GO:0033344 9.73 APOA1 APOB APOE
28 high-density lipoprotein particle assembly GO:0034380 9.72 APOA1 APOE
29 low-density lipoprotein particle remodeling GO:0034374 9.72 APOB APOE
30 low-density lipoprotein particle clearance GO:0034383 9.72 ADIPOQ APOB HMOX1
31 phospholipid efflux GO:0033700 9.71 APOA1 APOE
32 long-chain fatty acid transport GO:0015909 9.71 APOE PPARG
33 negative regulation of blood vessel diameter GO:0097756 9.71 CRP HMGCR
34 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.71 ADIPOQ APOA1
35 negative regulation of hormone secretion GO:0046888 9.7 ADIPOQ EDN1
36 positive regulation of cholesterol esterification GO:0010873 9.69 APOA1 APOE
37 high-density lipoprotein particle clearance GO:0034384 9.69 APOA1 APOE
38 negative regulation of vascular smooth muscle cell proliferation GO:1904706 9.69 ADIPOQ HMOX1 PPARG
39 chylomicron remnant clearance GO:0034382 9.68 APOB APOE
40 neuron projection regeneration GO:0031102 9.68 APOA1 APOE
41 negative regulation of blood coagulation GO:0030195 9.67 APOE EDN1 SERPINE1
42 regulation of Cdc42 protein signal transduction GO:0032489 9.66 APOA1 APOE
43 negative regulation of cellular protein metabolic process GO:0032269 9.66 APOE EDN1
44 very-low-density lipoprotein particle clearance GO:0034447 9.65 APOB APOE
45 membrane to membrane docking GO:0022614 9.65 ICAM1 VCAM1
46 adhesion of symbiont to host GO:0044406 9.64 HSPD1 ICAM1
47 lipoprotein catabolic process GO:0042159 9.63 APOB APOE
48 positive regulation of cholesterol efflux GO:0010875 9.63 ADIPOQ APOE PON1
49 cellular response to prostaglandin stimulus GO:0071379 9.61 APOB PPARG
50 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.61 ADIPOQ CRP PPARG

Molecular functions related to Arteriosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.76 ADIPOQ CCL2 EDN1 SPP1
2 phospholipid binding GO:0005543 9.46 APOA1 APOB APOE PON1
3 high-density lipoprotein particle binding GO:0008035 9.43 APOA1 HSPD1
4 lipid transporter activity GO:0005319 9.43 APOA1 APOB APOE
5 lipoprotein particle binding GO:0071813 9.4 APOA1 APOE
6 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.37 APOA1 APOE
7 low-density lipoprotein particle receptor binding GO:0050750 9.13 APOB APOE CRP
8 cholesterol transporter activity GO:0017127 8.8 APOA1 APOB APOE
9 protein binding GO:0005515 10.28 ADIPOQ APOA1 APOB APOE CCL2 COG2

Sources for Arteriosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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