MCID: ART021
MIFTS: 65

Arteriosclerosis malady

Cardiovascular diseases category

Summaries for Arteriosclerosis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Arteriosclerosis refers to a thickening and hardening of arterial walls in the arteries.... more...

MalaCards: Arteriosclerosis, also known as arteriosclerotic vascular disease nos, is related to arteriosclerosis obliterans and hypertension. An important gene associated with Arteriosclerosis is KL (klotho), and among its related pathways are Signaling by GPCR and TNF signaling pathway. The drugs isoxsuprine and epoprostenol and the compounds prostacyclin and atorvastatin have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and smooth muscle, and related mouse phenotypes are cardiovascular system and homeostasis/metabolism.

Aliases & Classifications for Arteriosclerosis

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8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

arteriosclerosis 8 44 60
arteriosclerotic vascular disease nos 8
arteriosclerotic vascular disease 8
arteriosclerosis nos 8


External Ids:

Disease Ontology8 DOID:2349
MeSH34 D001161
NCIt39 C34398

Related Diseases for Arteriosclerosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Arteriosclerosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 246)
idRelated DiseaseScoreTop Affiliating Genes
1arteriosclerosis obliterans31.5SELP, VCAM1, PTGIR, PF4, ICAM1, HGF
2hypertension30.8CCL2, VCAM1, PTGIR, EDN1, APOB, APOA1
3atherosclerosis30.6CCL2, ICAM1, ADIPOQ, SELP, VCAM1, PTGIR
4diabetes mellitus30.6ADIPOQ, SELP, VCAM1, PF4, EDN1, MGP
5myocardial infarction30.5ADIPOQ, SELP, PF4, AHSP, CD2, EDN1
6vascular disease30.4MGP, SELP, PF4
7ischemia30.4HGF, ICAM1, PDGFB, EDN1, AHSP, PF4
8coronary artery disease30.3CCL2, ADIPOQ, SELP, VCAM1, PF4, AHSP
9ischemic heart disease30.2APOA1, APOB, EDN1, AHSP, PF4, SELP
10pneumonia30.1ICAM1, CCL2
11essential hypertension30.1ADIPOQ, SELP, PF4, AHSP, CD2, EDN1
12acute myocardial infarction30.1SELP, PF4, AHSP, EDN1, APOB, APOA1
13type 2 diabetes mellitus30.1CCL2, APOA1, APOB, EDN1, DUSP2, CD63
14uremia30.1ADIPOQ, VCAM1, PF4
15vasculitis30.1CCL2, ICAM1, VCAM1, SELP
16hyperhomocysteinemia30.1SELP, VCAM1, CCL2
17intermittent claudication30.1PF4, SELP
18systemic lupus erythematosus30.0CCL2, ICAM1, CD2, VCAM1
19coronary stenosis29.9APOA1, APOB, SELP, ADIPOQ
20peripheral vascular disease29.9CCL2, VCAM1, SELP
21coronary heart disease29.7APOA1, APOB, MGP, EDN1, AHSP, PF4
22antiphospholipid syndrome29.7PF4, VCAM1, SELP
23obesity29.7CCL2, APOA1, APOB, ADIPOQ
24myeloma29.7HGF, ICAM1, PF4, VCAM1
25meningioma29.7PDGFB
26prostate cancer29.7HGF, CD63, MCAM
27arcus senilis29.7APOB, APOA1
28hepatitis29.7SELP, PDGFB, HGF
29thrombophilia29.7PF4, SELP
30blood platelet disease29.7PF4, SELP
31cadasil29.7APOB, CD63, PF4, SELP
32coronary arteriosclerosis11.0
33cerebritis10.8
34thromboangiitis obliterans10.3
35cerebral arteriosclerosis10.2
36aortic aneurysm10.2
37intracranial arteriosclerosis10.2
38kidney disease10.2
39angina pectoris10.1
40parkinson's disease10.1
41coronary aneurysm10.1
42monckeberg arteriosclerosis10.1
43nephrosclerosis10.1
44cerebral amyloid angiopathy10.1
45alzheimer's disease10.1
46coronary thrombosis10.1
47bronchopneumonia10.1
48aortic disease10.1
49lupus erythematosus10.1
50hypercholesterolemia10.0APOA1, APOB, EDN1, AHSP, VCAM1, SELP

Graphical network of the top 20 diseases related to Arteriosclerosis:



Diseases related to arteriosclerosis

Clinical Features for Arteriosclerosis

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Drugs & Therapeutics for Arteriosclerosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Arteriosclerosis

Drug clinical trials:

Search ClinicalTrials for Arteriosclerosis

Search NIH Clinical Center for Arteriosclerosis

Search CenterWatch for Arteriosclerosis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Arteriosclerosis

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Anatomical Context for Arteriosclerosis

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32MalaCards
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MalaCards organs/tissues related to Arteriosclerosis:

32
Heart, Endothelial, Smooth muscle, T cells, Kidney, Monocytes, Bone, Brain, Bone marrow, Testes, Skin, Liver, B cells, Spinal cord, Prostate, Lung, Pancreas, Spleen, Small intestine, Colon

Animal Models for Arteriosclerosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Arteriosclerosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538510.8ADIPOQ, KL, HGF, CCL2, ICAM1, PDGFB
2MP:000537610.7PF4, MCAM, PTGIR, VCAM1, SELP, ADIPOQ
3MP:000539710.7PF4, PTGIR, VCAM1, SELP, AHSP, APOA1
4MP:000538710.7PTGIR, ADIPOQ, SELP, VCAM1, KL, CCL2
5MP:001076810.7AHSP, PTGIR, VCAM1, SELP, ADIPOQ, EDN1
6MP:000537010.6ADIPOQ, SELP, APOB, APOA1, PDGFB, CCL2
7MP:000537810.5ADIPOQ, SELP, VCAM1, MGP, APOB, ICAM1
8MP:001077110.5PDGFB, AHSP, ADIPOQ, PTGIR
9MP:000536710.4CD63, EDN1, MGP, PDGFB, ADIPOQ, KL
10MP:000536910.2ADIPOQ, MGP, PDGFB, ICAM1, KL

Publications for Arteriosclerosis

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50PubMed
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Articles related to Arteriosclerosis:

(show top 50)    (show all 938)
idTitleAuthorsYear
1
Prospective study of sarpogrelate hydrochloride on patients with arteriosclerosis obliterans. (23364237)
2013
2
Vascular smooth muscle cell apoptosis promotes transplant arteriosclerosis through inducing the production of SDF-1I+. (22845908)
2012
3
Can the occurrence of gastrointestinal bleeding in nonpulsatile left ventricular assist device patients provide clues for the reversal of arteriosclerosis? (22062216)
2011
4
Adenosine diphosphate receptor P2Y12-mediated migration of host smooth muscle-like cells and leukocytes in the development of transplant arteriosclerosis. (21629176)
2011
5
Study design of SEASON registry: prospective Surveillance of cardiovascular Events in an Antiplatelet-treated arterioSclerosis Obliterans patients in JapaN )SEASON). (20966606)
2010
6
Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model. (20585280)
2010
7
Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the Mayo Clinic proteomic markers of arteriosclerosis study. (20140090)
2010
8
Probiotic therapy to men with incipient arteriosclerosis initiates increased bacterial diversity in colon: a randomized controlled trial. (19608185)
2010
9
Relation of stiffness parameter beta to carotid arteriosclerosis and silent cerebral infarction in patients on chronic hemodialysis. (19184511)
2009
10
Wild-type apo A-I and apo A-I(Milano) gene transfer reduce native and transplant arteriosclerosis to a similar extent. (19066833)
2009
11
Variance of expressions of extracellular matrix components and effects of anti-osteoporotic drugs on MAPnckeberg's arteriosclerosis]. (18311057)
2008
12
Lupus-associated endothelial dysfunction, disease activity and arteriosclerosis. (19032815)
2008
13
Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo. (17565319)
2007
14
Aggressive conservative therapy for refractory ulcer with diabetes and/or arteriosclerosis. (16700669)
2006
15
Prolonged cold preservation promotes the recipient's cell participating in neointima formation but delays the later graft arteriosclerosis in rat model. (15808628)
2005
16
Longitudinal left ventricular myocardial dysfunction assessed by 2D colour tissue Doppler imaging in a dog with systemic hypertension and severe arteriosclerosis. (15737177)
2005
17
The effect of Liple on physical and emotional quality of life in the treatment of arteriosclerosis obliterans. (15765038)
2004
18
Guidelines for peripheral percutaneous transluminal angioplasty of the abdominal aorta and lower extremity vessels. A statement for health professionals from a Special Writing Group of the Councils on Cardiovascular Radiology, Arteriosclerosis, Cardio-Thoracic and Vascular Surgery, Clinical Cardiology, and Epidemiology and Prevention, the American Heart Association. (14514865)
2003
19
Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins. (14517172)
2003
20
Treatment of arteriosclerosis. (12510249)
2003
21
Coronary arteriosclerosis in salmon: growing old or growing fast? (12095858)
2002
22
Origin of neointimal endothelium and alpha-actin-positive smooth muscle cells in transplant arteriosclerosis. (11390423)
2001
23
Prevention of cardiac allograft arteriosclerosis using antisense proliferating-cell nuclear antigen oligonucleotide. (10933173)
2000
24
Lower-extremity arteriosclerosis as a reflection of a systemic process: implications for concomitant coronary and carotid disease. (10777238)
1999
25
Multiglycosidorum tripterygii, a new immunosuppressant, supresses coronary arteriosclerosis after heart transplantation. (10328151)
1999
26
Comparative effects of vitamin K2 and vitamin E on experimental arteriosclerosis. (10052017)
1999
27
Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma. (9588888)
1998
28
Accelerated arteriosclerosis in aortic grafts: a role for cytokines in progressive intimal lesion development. (9636381)
1998
29
Reduced transplant arteriosclerosis in murine cardiac allografts placed in interferon-gamma knockout recipients. (9466561)
1998
30
Signal transduction in arteriosclerosis: mechanical stress-activated MAP kinases in vascular smooth muscle cells (review). (9852303)
1998
31
Exacerbated transplant arteriosclerosis in inducible nitric oxide-deficient mice. (9610537)
1998
32
Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts. (9239401)
1997
33
The relationship between endothelin-1, event-related P300 potentials, and prognosis in cerebral arteriosclerosis. (9100710)
1997
34
Blood coagulation disorders observed in arteriosclerosis obliterans]. (8808808)
1996
35
Graft coronary arteriosclerosis in rat heart transplant model with FK 506 short-term administration. (7533425)
1995
36
Six year experience with wrinkled ePTFE vascular prostheses for arteriosclerosis obliterans. (8268590)
1993
37
Coronary arteriosclerosis in dogfish (Scyliorhinus canicula). An assessment of some potential risk factors. (8499408)
1993
38
Coronary arteriosclerosis in Atlantic salmon. No regression of lesions after spawning. (3395273)
1988
39
Systolic hypertension in arteriosclerosis obliterans of the lower limbs. (6811168)
1982
40
Arteriosclerosis obliterans and associated risk factors in insulin-dependent and non-insulin-dependent diabetes. (7429028)
1980
41
Serum lipids and lipoproteins in arteriosclerosis obliterans of the lower extremities. (750857)
1978
42
Survival after arterial reconstruction in arteriosclerosis obliterans of the lower limbs. Follow-up after 10-20 years. (654831)
1978
43
Case report of death due to cardiac arrest or arrhythmia secondary to coronary arteriosclerosis in a 24 year-old aviator. (5095510)
1971
44
Chemicoanatomic studies in geographic pathology. A practical method for the quantitation of coronary arteriosclerosis. (13883504)
1962
45
Management of arteriosclerosis obliterans of the extremities. (13654008)
1959
46
Hypertension and coronary arteriosclerosis; a comparative study of the weights of kidneys in patients with acute myocardial infraction, systemic hypertension, carcinoma, and nonrenal disease. (13268199)
1955
47
Lipoproteins in general and cerebral arteriosclerosis; preliminary report. (14903194)
1952
48
Some limitations of lumbar sympathectomy in arteriosclerosis obliterans; early results in one hundred consecutive cases. (14877405)
1952
49
Arteriosclerosis obliterans as a cause of ulcer of the leg. (15398743)
1950
50
Tetraethyl ammonium chloride in the treatment of arteriosclerosis obliterans; preliminary report. (18145997)
1949

Genetic Variations for Arteriosclerosis

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Expression for genes affiliated with Arteriosclerosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Arteriosclerosis

Search GEO for disease gene expression data for Arteriosclerosis.

Pathways for genes affiliated with Arteriosclerosis

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Sources:
53Reactome, 29KEGG, 51QIAGEN, 37NCBI BioSystems Database
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Pathways related to Arteriosclerosis according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.5KL, CCL2, ICAM1, PDGFB, APOA1, APOB
210.5VCAM1, EDN1, ICAM1, CCL2
310.5SELP, VCAM1, CD2, ICAM1
410.5ICAM1, APOA1, VCAM1
5
Hide members
10.5HGF, CCL2, PDGFB, PTGIR, VCAM1
610.5CCL2, ICAM1, VCAM1
710.5CCL2, ICAM1, APOA1, APOB
810.5ICAM1, APOB, SELP
910.5SELP, CD2, APOB
10
Hide members
10.5CD2, PDGFB, HGF
11
Hide members
10.5SELP, PF4, CD63, APOA1, PDGFB, HGF
1210.5APOB, APOA1
13
Hide members
10.5HGF, PDGFB, APOA1, APOB, CD2, CD63
1410.5PTGIR

Compounds for genes affiliated with Arteriosclerosis

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Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Arteriosclerosis according to GeneCards/GeneDecks:

(show top 50)    (show all 178)
idCompoundScoreTop Affiliating Genes
1prostacyclin4411.0SELP, ADIPOQ, VCAM1, PTGIR, HGF, ICAM1
2atorvastatin44 49 28 11 2415.0ADIPOQ, VCAM1, APOB, EDN1, APOA1, ICAM1
3fibrinogen4411.0ADIPOQ, CCL2, PF4, ICAM1, APOA1, APOB
4fenofibrate44 49 1113.0APOB, ADIPOQ, SELP, ICAM1, APOA1, VCAM1
5pravastatin44 49 28 11 2415.0ICAM1, ADIPOQ, APOB, SELP, VCAM1, CCL2
6homocysteine44 2411.9VCAM1, APOB, AHSP, CCL2, APOA1, SELP
7aspirin44 49 28 2413.9APOB, SELP, PF4, DUSP2, CD63, HGF
8dextran sulfate4410.9HGF, ICAM1, APOA1, APOB, SELP, PF4
9lactate4410.9VCAM1, HGF, ICAM1, APOA1, APOB, CD63
10vegf4410.9ICAM1, VCAM1, KL, HGF, EDN1, CCL2
11lipid4410.9APOB, APOA1, HGF, CD2, CD63, AHSP
12simvastatin44 49 59 28 11 2415.9CCL2, ICAM1, APOB, VCAM1, SELP, ADIPOQ
13fluvastatin44 49 28 1113.9SELP, VCAM1, APOB, CCL2, ICAM1, APOA1
14cholesterol44 28 11 2413.9APOB, MGP, CD63, PF4, VCAM1, SELP
15pge24410.9PF4, AHSP
16histamine44 28 2412.9CCL2, SELP, VCAM1, PF4, AHSP, EDN1
17rantes4410.9PF4, ICAM1
18probucol44 1111.9VCAM1, EDN1, CCL2, APOA1, APOB
19losartan44 49 28 1113.9EDN1, HGF, VCAM1, CCL2, ADIPOQ, SELP
20cilostazol44 1111.9HGF, VCAM1, CCL2, PF4
21genistein44 28 59 2 11 2415.9ICAM1, CCL2, EDN1, HGF, APOB, VCAM1
228-isoprostane4410.9ADIPOQ, EDN1, ICAM1, CCL2, VCAM1
23sodium nitroprusside4410.9AHSP, SELP, VCAM1, ADIPOQ, HGF, EDN1
24norepinephrine44 11 2412.9AHSP
25iloprost44 59 28 1113.9PTGIR, SELP, EDN1, VCAM1, PF4
26thromboxane a244 2411.9PF4, PTGIR, SELP, EDN1, AHSP, CD63
27pdmp4410.9CD63, DUSP2, ICAM1, SELP
28fenofibric acid44 2811.9CCL2, APOB, ADIPOQ, APOA1
29polysaccharide4410.8HGF, CCL2, ICAM1, APOB, PF4, SELP
30dexamethasone44 49 28 1113.8ADIPOQ, PDGFB, HGF
31phosphatidylinositol4410.8DUSP2, ADIPOQ, HGF, CCL2, ICAM1, EDN1
32creatinine4410.8APOA1, APOB, SELP, ADIPOQ
33glucose4410.8CD63, APOA1, AHSP, PF4, CD2
34nitric oxide44 11 2412.8AHSP, ICAM1, PDGFB, EDN1, CD63, PTGIR
35thromboxane44 2411.8PF4, PTGIR, AHSP, EDN1, SELP
36adenylate4410.8APOB, HGF, PF4, PTGIR, VCAM1, SELP
37valsartan44 59 28 1113.8ADIPOQ, SELP, EDN1, CCL2
38isoproterenol44 1111.8AHSP, PTGIR, VCAM1, EDN1, APOB, CCL2
39wortmannin4410.8ADIPOQ, HGF, PF4, CD63, CD2, CCL2
40pioglitazone44 49 28 1113.7CCL2, ADIPOQ, VCAM1, APOA1, APOB
41tyrosine4410.7CD63, SELP, VCAM1, MCAM, CD2, DUSP2
42mdmp4410.7DUSP2, CD63, SELP
43calcium44 49 11 2413.7CD2, EDN1, DUSP2, MCAM, PF4, AHSP
44arachidonic acid44 28 11 2413.6PTGIR, PF4, AHSP, CD63, EDN1, HGF
45cuprophan4410.6ICAM1, VCAM1, SELP, PF4
46estrogen4410.5AHSP, MGP
47enalapril44 49 1112.5ADIPOQ, EDN1, HGF, APOA1
48cerivastatin44 49 28 1113.5APOB, APOA1, ICAM1, CCL2
49arginine4410.4AHSP, PF4, VCAM1, SELP, EDN1, CCL2
50sb 20358044 5911.2ICAM1, CCL2, EDN1, VCAM1, ADIPOQ, HGF

GO Terms for genes affiliated with Arteriosclerosis

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Sources:
16Gene Ontology
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Cellular components related to Arteriosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00561510.7ADIPOQ, KL, HGF, CCL2, ICAM1, PDGFB
2extracellular regionGO:00557610.6PDGFB, CCL2, HGF, KL, APOA1, APOB
3plasma membraneGO:00588610.5ICAM1, APOA1, APOB, CD2, CD63, MCAM
4external side of plasma membraneGO:00989710.5ICAM1, CD2, MCAM, VCAM1, SELP
5platelet alpha granule lumenGO:03109310.4HGF, PDGFB, PF4
6platelet dense granule membraneGO:03108810.2SELP, CD63

Biological processes related to Arteriosclerosis according to GeneCards/GeneDecks:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:00759610.9SELP, HGF, PDGFB, APOA1, APOB, CD2
2cellular response to tumor necrosis factorGO:07135610.9EDN1, APOB, ICAM1, CCL2
3response to hypoxiaGO:00166610.9CCL2, PDGFB, EDN1, VCAM1, ADIPOQ
4platelet degranulationGO:00257610.9HGF, PDGFB, APOA1, CD63, PF4, SELP
5platelet activationGO:03016810.9HGF, PDGFB, APOA1, CD63, PF4, SELP
6response to amino acid stimulusGO:04320010.9CCL2, ICAM1, EDN1
7leukocyte cell-cell adhesionGO:00715910.9ICAM1, VCAM1, SELP
8leukocyte migrationGO:05090010.9ICAM1, APOB, CD2, SELP
9response to lipopolysaccharideGO:03249610.9SELP, PTGIR, EDN1, APOB
10heterophilic cell-cell adhesionGO:00715710.9ICAM1, VCAM1, SELP
11cellular response to interleukin-1GO:07134710.8EDN1, ICAM1, CCL2
12organ regenerationGO:03110010.8HGF, CCL2, APOA1
13positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406810.8SELP, PDGFB, HGF
14lipoprotein biosynthetic processGO:04215810.8APOA1, APOB
15membrane to membrane dockingGO:02261410.8ICAM1, VCAM1
16cell adhesionGO:00715510.8SELP, VCAM1, MCAM, ICAM1, CCL2
17maternal process involved in parturitionGO:06013710.8CCL2, EDN1
18negative regulation of heterotypic cell-cell adhesionGO:03411510.8APOA1, ADIPOQ
19negative regulation of platelet-derived growth factor receptor signaling pathwayGO:01064210.8ADIPOQ, PTGIR
20negative regulation of tumor necrosis factor-mediated signaling pathwayGO:01080410.8ADIPOQ, APOA1
21cytokine-mediated signaling pathwayGO:01922110.7CCL2, ICAM1, PF4, VCAM1
22positive regulation of peptidyl-tyrosine phosphorylationGO:05073110.7HGF, PDGFB, ADIPOQ
23response to nutrientGO:00758410.7APOA1, VCAM1, ADIPOQ
24positive regulation of DNA biosynthetic processGO:200057310.7HGF, PDGFB
25low-density lipoprotein particle clearanceGO:03438310.7APOB, ADIPOQ
26response to ethanolGO:04547110.6ADIPOQ, ICAM1, CCL2
27negative regulation of hormone secretionGO:04688810.6ADIPOQ, EDN1
28leukocyte tethering or rollingGO:05090110.6VCAM1, SELP
29response to drugGO:04249310.5APOA1, PDGFB, ICAM1, CCL2
30cholesterol transportGO:03030110.5APOB, APOA1
31agingGO:00756810.4KL, CCL2, VCAM1
32acute inflammatory responseGO:00252610.2VCAM1, KL

Molecular functions related to Arteriosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heparin bindingGO:00820110.5SELP, PF4, APOB, CCL2
2cholesterol transporter activityGO:01712710.5APOB, APOA1
3sialic acid bindingGO:03369110.4SELP, ADIPOQ
4hormone activityGO:00517910.2ADIPOQ, EDN1, KL

Products for genes affiliated with Arteriosclerosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Arteriosclerosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet