Aliases & Classifications for Artery Disease

MalaCards integrated aliases for Artery Disease:

Name: Artery Disease 12 14
Arteriopathic Disease 69

Characteristics:

HPO:

32
artery disease:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:0050828
SNOMED-CT via HPO 65 263681008 49601007

Summaries for Artery Disease

Disease Ontology : 12 A vascular disease that is located in an artery.

MalaCards based summary : Artery Disease, also known as arteriopathic disease, is related to hypercholesterolemia, due to ligand-defective apo b and myocardial infarction, and has symptoms including abnormality of the cardiovascular system An important gene associated with Artery Disease is APOA1 (Apolipoprotein A1), and among its related pathways/superpathways are Lipoprotein metabolism and Metabolism of fat-soluble vitamins. The drugs Everolimus and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and testes, and related phenotypes are Decreased free cholesterol and cardiovascular system

Wikipedia : 72 Artery disease are a narrowing or constriction of the arteries may refer to the... more...

Related Diseases for Artery Disease

Diseases related to Artery Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 337)
id Related Disease Score Top Affiliating Genes
1 hypercholesterolemia, due to ligand-defective apo b 32.2 APOB APOE
2 myocardial infarction 32.2 ABCA1 APOA1 APOA2 APOA5 APOB APOE
3 hyperlipidemia, familial combined 32.1 APOA1 APOA2 APOA5 APOB APOE
4 sitosterolemia 31.8 ABCG5 ABCG8 APOB
5 peripheral artery disease 31.6 ABCA1 ABCG5 ABCG8 ACTA2 ADAMTS7 ALOX15
6 angina pectoris 31.4 APOA1 APOB SELE
7 pericarditis 30.5 APOA1 APOB APOE PON1 SELE
8 arthritis 30.2 ABCA1 ABCG5 ABCG8 APOE PON1
9 coronary artery disease 12.3
10 carotid artery disease 12.2
11 coronary artery disease, autosomal dominant, 1 12.0
12 coronary artery disease, autosomal dominant, 2 12.0
13 cerebral arterial disease 11.9
14 renal artery disease 11.9
15 lrp6-related coronary artery disease susceptibility 11.7
16 mef2a-related coronary artery disease susceptibility 11.7
17 deafness peripheral neuropathy arterial disease 11.7
18 peripheral vascular disease 11.6
19 hyperlipoproteinemia, type iii 11.3
20 hypercholesterolemia, familial 11.2
21 abdominal obesity-metabolic syndrome 3 11.2
22 atherosclerosis 11.2
23 islet cell tumor 11.0 APOA1 APOB APOE
24 melorheostosis 11.0 APOA1 APOB APOE PON1
25 alzheimer disease-2 11.0 APOA1 APOA5 APOB APOE
26 xk aprosencephaly 11.0 APOB APOE
27 cataract, autosomal dominant congenital 4 11.0 APOB APOE SELE
28 delta-1-pyrroline-5-carboxylate dehydrogenase deficiency 11.0 APOB APOE LCAT
29 cardiovascular disease risk factor ) 11.0
30 glossopharyngeal nerve disease 11.0 APOA1 APOB APOE SELE
31 joubert syndrome 21 11.0 ABCA1 APOA1 APOB
32 migraine with or without aura 1 11.0 APOA1 APOA2 APOB APOE
33 aquagenic syringeal acrokeratoderm 11.0 APOA1 LCAT
34 intermittent claudication 10.9
35 fetal parvovirus syndrome 10.9 APOA1 APOB LCAT
36 myelophthisic anemia 10.9 APOA1 APOB APOE PON1 SELE
37 wolfram syndrome 2 10.9 APOA1 APOB APOE LCAT
38 chondrocalcinosis with early-onset osteoarthritis 10.9 APOA1 APOB APOE LCAT PON1
39 familial osteochondritis dissecans 10.9 APOA1 APOA2 APOE LCAT
40 acute apical periodontitis 10.9 APOA1 APOB APOE LCAT
41 short stature, brachydactyly, intellectual developmental disability, and seizures 10.9 APOA1 APOA2 LCAT
42 mechanical entropion 10.9 APOE HP
43 hypobetalipoproteinemia 10.9 APOB APOE LCAT
44 mental retardation, autosomal dominant 45 10.9 APOA2 APOB APOE LCAT
45 critical limb ischemia 10.9
46 skin squamous cell carcinoma 10.9 APOA1 APOA5 APOB APOE LCAT
47 hyperchylomicronemia, late-onset 10.9 APOA1 APOA2 APOA5 APOB APOE
48 heart disease 10.9
49 stone in bladder diverticulum 10.9 APOA1 APOA2 APOB APOE LCAT
50 pontocerebellar hypoplasia 10.9 ABCG8 APOA1 APOB APOE

Graphical network of the top 20 diseases related to Artery Disease:



Diseases related to Artery Disease

Symptoms & Phenotypes for Artery Disease

Human phenotypes related to Artery Disease:

32
id Description HPO Frequency HPO Source Accession
1 abnormality of the cardiovascular system 32 HP:0001626

GenomeRNAi Phenotypes related to Artery Disease according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 9.17 ABCA1 ABCG8 APOA1 APOA5 APOB APOE

MGI Mouse Phenotypes related to Artery Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.07 ABCA1 ABCG5 ACTA2 ADAMTS7 ALOX15 APOA1
2 cellular MP:0005384 10 ABCG8 ADAMTS7 ALOX15 APOA1 APOB APOE
3 homeostasis/metabolism MP:0005376 9.86 ABCG8 ADAMTS7 ALOX15 APOA1 APOA2 APOA5
4 liver/biliary system MP:0005370 9.36 ABCA1 ABCG5 ABCG8 ADAMTS7 APOA1 APOB

Drugs & Therapeutics for Artery Disease

Drugs for Artery Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1004)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
4
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
5
Ticlopidine Approved Phase 4,Phase 2,Phase 3,Phase 1 55142-85-3 5472
6
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 55-56-1 9552079 2713
7
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
8
Tirofiban Approved Phase 4,Phase 3,Phase 1 144494-65-5 60947
9
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 79902-63-9 54454
10
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
11
Metformin Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 657-24-9 14219 4091
12
Zinc Approved Phase 4,Phase 3,Phase 1,Early Phase 1 7440-66-6 32051 23994
13
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-78-2 2244
14
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
15
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
16
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 142387-99-3, 95635-55-5 56959
17
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
18
Warfarin Approved Phase 4,Phase 3,Phase 2 81-81-2 6691 54678486
19
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
20
Chromium Approved Phase 4,Phase 2,Phase 3,Phase 1 7440-47-3 27668
21
Cilostazol Approved Phase 4,Phase 3,Phase 2,Phase 1 73963-72-1 2754
22
Rosiglitazone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 122320-73-4 77999
23
Acarbose Approved, Investigational Phase 4,Phase 3 56180-94-0 441184
24
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
25
Ezetimibe Approved Phase 4,Phase 2,Phase 3,Phase 1 163222-33-1 150311
26
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 37350-58-6, 51384-51-1 4171
27
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-61-7 60961
28
Dipyridamole Approved Phase 4,Phase 3,Phase 2,Phase 1 58-32-2 3108
29
Regadenoson Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 313348-27-5 219024
30
Coal tar Approved Phase 4,Phase 1,Phase 2 8007-45-2
31
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
32
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
33
Dopamine Approved Phase 4,Phase 2,Phase 3 51-61-6, 62-31-7 681
34
Fenoldopam Approved Phase 4 67227-56-9, 67227-57-0 3341
35
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
36
Thrombin Approved Phase 4,Phase 3,Phase 2
37
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
38
Nicorandil Approved Phase 4 65141-46-0 47528
39
Phenprocoumon Approved Phase 4 435-97-2 9908 54680692
40
Esmolol Approved Phase 4,Phase 3 103598-03-4, 81147-92-4 59768
41
Nicardipine Approved Phase 4,Early Phase 1 55985-32-5 4474
42 Trapidil Approved Phase 4 15421-84-8
43
Bisoprolol Approved Phase 4,Phase 2,Phase 3,Early Phase 1 66722-44-9 2405
44
Candesartan Approved Phase 4,Phase 3 139481-59-7 2541
45
Diltiazem Approved Phase 4,Phase 3 42399-41-7 39186
46
Ramipril Approved Phase 4,Phase 3,Phase 2 87333-19-5 5362129
47
Etanercept Approved, Investigational Phase 4 185243-69-0
48
Ustekinumab Approved, Investigational Phase 4 815610-63-0
49
Udenafil Approved, Investigational Phase 4,Phase 2 268203-93-6 6918523
50
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816

Interventional clinical trials:

(show top 50) (show all 6408)

id Name Status NCT ID Phase Drugs
1 The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease Unknown status NCT01508663 Phase 4 ARB, CCB, ACE-inhibitor, statin, Nitrate, Antiplate etc.
2 Safety and Efficacy of Low-dose Ticagrelor in Chinese Patients With Stable Coronary Artery Disease Unknown status NCT02514642 Phase 4 low-dose ticagrelor;Clopidogrel
3 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
4 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
5 The Association Between Very Small Embryonic-like Stem Cells and the Prognosis of Coronary Artery Disease Patients Unknown status NCT01633359 Phase 4 Intensive statin;Routine statin
6 Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease Unknown status NCT01373632 Phase 4
7 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4 tirofiban
8 Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa) Unknown status NCT02030054 Phase 4 Atorvastatin;Rosuvastatin
9 Low-dose Statins and Nutraceuticals in High-intensity Statin-intolerant Patients Unknown status NCT02001883 Phase 4 Association low-dose statin and nutraceuticals
10 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4 insulin glargine;metformin
11 Residual Platelet Activity In Advanced Peripheral Artery Disease Unknown status NCT01627431 Phase 4 Acetylsalicylic acid;Clopidogrel
12 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
13 Xience/Promus for Long Coronary Lesion Registry Unknown status NCT01147237 Phase 4
14 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4
15 Pharmacodynamic Effects of Atorvastatin vs. Rosuvastatin on Platelet Reactivity Unknown status NCT01567774 Phase 4 Atorvastatin;Rosuvastatin
16 Effects of Nicotinic Acid Plus Simvastatin Versus Simvastatin Alone on Carotid and Femoral Intima-Media Thickness in Patients With Peripheral Artery Disease (NASCIT) Unknown status NCT00712049 Phase 4 simvastatin;Nicotinic Acid
17 Efficacy Study of Stenting, Paclitaxel Eluting Balloon or Atherectomy to Treat Peripheral Artery Disease Unknown status NCT00986752 Phase 4
18 Pharmacodynamic Effects of Ranolazine Versus Amlodipine on Platelet Reactivity Unknown status NCT01490255 Phase 4 Ranolazine;Amlodipine
19 Rivaroxaban in Patients With Atrial Fibrillation and Coronary Artery Disease Undergoing Percutaneous Coronary Intervention Unknown status NCT02334254 Phase 4 rivaroxaban and ticagrel therapy;triple antithrombotic regimen with warfarin, asipirin and clopidogrel
20 Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease Unknown status NCT01901224 Phase 4 Metformin 1000 mg;Placebo
21 Safety and Effectiveness of the Coronary Momo Stent Unknown status NCT01535625 Phase 4
22 Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease Unknown status NCT01038050 Phase 4 Ginkgo Biloba Extract (GBE)
23 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
24 Assessment of Surface Coverage of Two Types of DES in Diabetes Mellitus and Non- Diabetes Mellitus Unknown status NCT01023919 Phase 4
25 Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease Unknown status NCT00917527 Phase 4 Atorvastatin
26 Rosiglitazone Therapy In The Prevention Of Coronary Artery Disease In Patients With Impaired Glucose Tolerance Unknown status NCT00733174 Phase 4 Rosiglitazone;Placebo
27 Overcoming High On-Treatment Platelet Reactivity (HPR) During Prasugrel Therapy With Ticagrelor Unknown status NCT01869309 Phase 4 Prasugrel;Ticagrelor
28 SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy Unknown status NCT00403078 Phase 4
29 Multivessel Stenting Versus Staged Revascularization With Zotarolimus-eluting Stent for STEMI Unknown status NCT01781715 Phase 4
30 Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial) Unknown status NCT00858676 Phase 4 acarbose
31 A Multicenter, Therapeutic Used Study to Evaluate the Efficacy and Safety of Pletaal SR Capsule (Cilostazol) in Subjects With Peripheral Arterial Disease Symptom Due to Chronic Occlusive Arterial Disease Unknown status NCT01711333 Phase 4 Pletaal SR capsule
32 Platelets Induced Vasodilation, in Vitro and in Vivo Study Unknown status NCT00152646 Phase 4 placebo, aspirine, clopidogrel
33 Ranolazine, Ethnicity and the Metabolic Syndrome Unknown status NCT01304095 Phase 4 Ranolazine
34 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
35 Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents Unknown status NCT01268371 Phase 4
36 Italian Diffuse/Multivessel Disease ABSORB Prospective Registry: IT-Disappears Unknown status NCT02004730 Phase 4
37 A Registry To Evaluate Safety And Effectiveness Of Everolimus Drug Eluting Stent For Coronary Revascularization Unknown status NCT01157455 Phase 4 Aspirin;Clopidogrel;Heparin or Bivalirudin
38 The Effects of Omega 3 and Vitamin E Supplementation on the Serum Antioxidant Enzymes and Gene Expressions of PGC-1a, h TERT, FOXOs and SIRTs in CAD Patients Unknown status NCT02011906 Phase 4
39 Diagnostic Performance of Noninvasive Fractional Flow Reserve From Computed Tomography Unknown status NCT01747317 Phase 4
40 Comparison of the Everolimus Eluting With the Biolimus A9 Eluting Stent Unknown status NCT01233453 Phase 4
41 Graft Patency After FFR-guided Versus Angio-guided CABG (GRAFFITI) Trial Unknown status NCT01810224 Phase 4
42 Atorvastatin Plus Ezetimibe on Coronary Plaque Progression Unknown status NCT01086020 Phase 4 atorvastatin;atorvastatin plus ezetimibe
43 Efficacy and Safety of Paclitaxel-eluting Balloon for Treatment of Lesions in Native Small Coronary Arteries Unknown status NCT01903902 Phase 4
44 Effect of Statins on the Radial Intima-media Thickness After Transradial Angioplasty Unknown status NCT00952770 Phase 4
45 Apposition Assessed Using Optical Coherence Tomography of Chromium Stents Eluting Everolimus From Cobalt Versus Platinum Alloy Platforms Unknown status NCT01776567 Phase 4
46 Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns Unknown status NCT01024179 Phase 4
47 Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease Unknown status NCT01418794 Phase 4
48 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
49 Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty Unknown status NCT00262574 Phase 4 Nesiritide,
50 Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease Unknown status NCT00144937 Phase 4 Stepwise therapy for dyslipidemia, hypertension and diabetes

Search NIH Clinical Center for Artery Disease

Genetic Tests for Artery Disease

Anatomical Context for Artery Disease

MalaCards organs/tissues related to Artery Disease:

39
Heart, Endothelial, Testes, Kidney, Bone, Bone Marrow, Brain

Publications for Artery Disease

Articles related to Artery Disease:

(show top 50) (show all 4911)
id Title Authors Year
1
Circulating Levels of LAMP2 in Coronary Artery Disease: Association with Serum Lipid Profile. ( 27923262 )
2017
2
A molecular case-control study of association of HNF1A gene polymorphisms (rs2259816 and rs7310409) with risk of coronary artery disease in Iranian patients. ( 28222501 )
2017
3
Promoter Polymorphism of Toll-Like Receptor 4 is Associated with a Decreased Risk of Coronary Artery Disease: A Case-Control Study in the Chinese Han Population. ( 28092654 )
2017
4
Carotid versus coronary atherosclerosis burdens in acute compared with chronic symptomatic coronary artery disease. ( 28520469 )
2017
5
Carotid Duplex Ultrasonography: Additional Imaging Is Rarely Necessary for Appropriate Treatment Planning for Carotid Artery Disease. ( 28424133 )
2017
6
Coronary Artery Disease-Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes. ( 28279971 )
2017
7
Drug-eluting stent placement versus coronary artery bypass surgery for unprotected left main coronary artery disease: A meta-analysis of randomized controlled trials. ( 28081585 )
2017
8
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. ( 28530674 )
2017
9
Prognostic Value of Coronary CT Angiography With Selective PET Perfusion Imaging in Coronary Artery Disease. ( 28528146 )
2017
10
The association of the circle of Willis anomaly and risk of stroke in patients with carotid artery disease. ( 28746428 )
2017
11
Inter-ethnic marriages and severity of coronary artery disease: A multicenter study of Arabian Gulf States. ( 28515856 )
2017
12
Paradoxical coronary artery disease in humans with hyperalphalipoproteinemia is associated with distinct differences in the high-density lipoprotein phosphosphingolipidome. ( 28826666 )
2017
13
Association of factor XIII Val34Leu polymorphism and coronary artery disease: A meta-analysis. ( 27665853 )
2017
14
Cytokines and MicroRNA in Coronary Artery Disease. ( 28939213 )
2017
15
Regional variation in patient selection and treatment for carotid artery disease in the Vascular Quality Initiative. ( 28359719 )
2017
16
Association between STK11 Gene Polymorphisms and Coronary Artery Disease in Type 2 Diabetes in Han Population in China. ( 28349069 )
2017
17
Meta-Analysis Comparing Coronary Artery Bypass Grafting to Drug-Eluting Stents and to Medical Therapy Alone for Left Main Coronary Artery Disease. ( 28532780 )
2017
18
Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study. ( 28473441 )
2017
19
The relationship of plasma decoy receptor 3 and coronary collateral circulation in patients with coronary artery disease. ( 28942284 )
2017
20
Quality of Life in Patients with Coronary Artery Disease and Panic Disorder: A Comparative Study. ( 28042398 )
2017
21
Fibromuscular Dysplasia with Spontaneous Coronary Artery Disease Presenting as Acute Myocardial Infarction. ( 28652952 )
2017
22
Same Day Discharge versus Overnight Stay in the Hospital following Percutaneous Coronary Intervention in Patients with Stable Coronary Artery Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( 28068415 )
2017
23
Acquired coronary artery disease in adult patients with congenital heart disease: a true or a false problem? ( 28072626 )
2017
24
The Effect of Structured Patient Education on Physical Activity in Patients with Peripheral Arterial Disease and Intermittent Claudication: A Systematic Review. ( 28528678 )
2017
25
Peripheral Endothelial Function and Coronary Flow Velocity Reserve Are Not Associated in Women with Angina and No Obstructive Coronary Artery Disease: The iPOWER Study. ( 28942444 )
2017
26
Biobanking in carotid artery disease: translation to clinical practice. ( 28051291 )
2017
27
Assessing and Modifying Coronary Artery Disease Risk in Women. ( 28523440 )
2017
28
Crural Index and extensive atherosclerosis of crural vessels are associated with long-term cardiovascular mortality in patients with symptomatic peripheral artery disease. ( 28763728 )
2017
29
PGC-1I+ (Peroxisome Proliferator-Activated Receptor I^ Coactivator 1-I+) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure. ( 28533333 )
2017
30
The synergistic effect of vascular cell adhesion molecule-1 and coronary artery disease on brain-derived neurotrophic factor. ( 28131673 )
2017
31
Effects of Obstructive Carotid Artery Disease on Ocular Circulation and the Safety of Carotid Artery Stenting. ( 28162948 )
2017
32
First Experience With the Coronary Sinus Reducer System for the Management of Refractory Angina in Patients Without Obstructive Coronary Artery Disease. ( 28935084 )
2017
33
Association of arterial calcification with chronic limb ischemia in patients with peripheral artery disease. ( 28870682 )
2017
34
Omentin Val109Asp polymorphism and risk of coronary artery disease. ( 28325076 )
2017
35
Peripheral Artery Disease: To Screen or Not Screen, That Is the Question! ( 28868916 )
2017
36
Elevated levels of preI^1-high-density lipoprotein are associated with cholesterol ester transfer protein, the presence and severity of coronary artery disease. ( 28073362 )
2017
37
Cardiovascular Risk and Known Coronary Artery Disease Are Associated With Colorectal Adenoma and Advanced Neoplasia. ( 28473143 )
2017
38
Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease. ( 27959717 )
2017
39
Predictive value of non-fasting remnant cholesterol for short-term outcome of diabetics with new-onset stable coronary artery disease. ( 28086966 )
2017
40
Growth Differentiation Factor 15 Is Associated With Major Amputation and Mortality in Patients With Peripheral Artery Disease. ( 28855167 )
2017
41
Re: The Survival Benefit of Kidney Transplantation in the Setting of Combined Peripheral Arterial Disease and End-Stage Renal Failure. ( 28208552 )
2017
42
Phosphodiesterase type 5 inhibition may reduce diastolic function in women with ischemia but no obstructive coronary artery disease. ( 28528579 )
2017
43
Mitochondrial DNA heteroplasmy in cardiac tissue from individuals with and without coronary artery disease. ( 28521548 )
2017
44
Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction. ( 28515848 )
2017
45
Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease. ( 28835113 )
2017
46
The addition of vildagliptin to metformin prevents the elevation of interleukin 1A9 in patients with type 2 diabetes and coronary artery disease: a prospective, randomized, open-label study. ( 28532406 )
2017
47
Atherosclerotic and thrombotic genetic and environmental determinants in Egyptian coronary artery disease patients: a pilot study. ( 28086795 )
2017
48
Sestrins increase in patients with coronary artery disease and associate with the severity of coronary stenosis. ( 28732653 )
2017
49
Association between apolipoprotein E polymorphisms and premature coronary artery disease: a meta-analysis. ( 27394044 )
2017
50
The Relationship Between Peripheral Artery Disease Symptomatology and Ischemia. ( 28858146 )
2017

Variations for Artery Disease

Expression for Artery Disease

Search GEO for disease gene expression data for Artery Disease.

Pathways for Artery Disease

Pathways related to Artery Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.14 ABCA1 ABCG5 ABCG8 APOA1 APOA2 APOA5
2
Show member pathways
12.06 APOA1 APOA2 APOB APOE
3 11.71 ACTA2 APOE ITGA2 LRP6
4
Show member pathways
11.69 APOA1 APOB APOE HP
5 11.49 APOA1 APOA2 APOA5
6
Show member pathways
11.2 ABCA1 ABCG5 ABCG8 APOA1 APOB
7
Show member pathways
11.11 ABCA1 ABCG5 ABCG8 APOA1 APOA2 APOA5
8 10.91 APOA1 APOA2 APOA5
9 10.71 ABCA1 APOA1 APOA2

GO Terms for Artery Disease

Cellular components related to Artery Disease according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.95 ABCA1 ADAMTS7 APOA1 ITGA2 LRP6
2 endoplasmic reticulum lumen GO:0005788 9.95 ADAMTS7 APOA1 APOA2 APOA5 APOB APOE
3 early endosome GO:0005769 9.89 APOA1 APOA2 APOB APOE LRP6
4 blood microparticle GO:0072562 9.88 APOA1 APOA2 APOA5 APOE HP PON1
5 spherical high-density lipoprotein particle GO:0034366 9.63 APOA1 APOA2 PON1
6 endocytic vesicle lumen GO:0071682 9.62 APOA1 APOB APOE HP
7 low-density lipoprotein particle GO:0034362 9.56 APOA1 APOA5 APOB APOE
8 very-low-density lipoprotein particle GO:0034361 9.55 APOA1 APOA2 APOA5 APOB APOE
9 ATP-binding cassette (ABC) transporter complex GO:0043190 9.54 ABCG5 ABCG8
10 intermediate-density lipoprotein particle GO:0034363 9.54 APOA1 APOB APOE
11 chylomicron GO:0042627 9.35 APOA1 APOA2 APOA5 APOB APOE
12 discoidal high-density lipoprotein particle GO:0034365 9.21 APOA1
13 high-density lipoprotein particle GO:0034364 9.17 ABCA1 APOA1 APOA2 APOA5 APOE LCAT
14 extracellular region GO:0005576 10.22 ADAMTS7 APOA1 APOA2 APOA5 APOB APOE
15 extracellular space GO:0005615 10.17 ACTA2 ADAMTS7 APOA1 APOA2 APOA5 APOB

Biological processes related to Artery Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 57)
id Name GO ID Score Top Affiliating Genes
1 lipid transport GO:0006869 9.99 APOA1 APOA2 APOA5 APOB APOE
2 steroid metabolic process GO:0008202 9.97 ABCA1 APOA1 APOB APOE LCAT
3 cholesterol metabolic process GO:0008203 9.95 ABCA1 APOA1 APOA2 APOB APOE LCAT
4 regulation of lipid metabolic process GO:0019216 9.94 ABCA1 APOA1 APOA2 APOA5
5 response to nutrient GO:0007584 9.93 ABCA1 ABCG5 ABCG8 APOA1
6 retinoid metabolic process GO:0001523 9.92 APOA1 APOA2 APOB APOE
7 phospholipid transport GO:0015914 9.86 ABCA1 ABCG8 APOA1
8 triglyceride metabolic process GO:0006641 9.86 APOA2 APOA5 APOE
9 phosphatidylcholine biosynthetic process GO:0006656 9.85 APOA1 APOA2 LCAT
10 cholesterol transport GO:0030301 9.85 ABCA1 APOA1 APOA2 APOB LCAT
11 triglyceride catabolic process GO:0019433 9.84 APOA1 APOA5 APOB APOE
12 triglyceride homeostasis GO:0070328 9.83 APOA1 APOA5 APOE
13 high-density lipoprotein particle remodeling GO:0034375 9.83 APOA1 APOA2 APOE LCAT
14 high-density lipoprotein particle assembly GO:0034380 9.83 ABCA1 APOA1 APOA2 APOA5 APOE
15 chylomicron assembly GO:0034378 9.81 APOA1 APOA2 APOB APOE
16 positive regulation of cholesterol efflux GO:0010875 9.8 ABCA1 APOE PON1
17 positive regulation of cholesterol esterification GO:0010873 9.8 APOA1 APOA2 APOA5 APOE
18 lipoprotein metabolic process GO:0042157 9.8 ABCA1 APOA1 APOA2 APOA5 APOB APOE
19 low-density lipoprotein particle remodeling GO:0034374 9.79 APOA2 APOB APOE
20 chylomicron remodeling GO:0034371 9.78 APOA1 APOA2 APOB APOE
21 phosphatidylcholine metabolic process GO:0046470 9.77 APOA5 LCAT PON1
22 phospholipid efflux GO:0033700 9.77 ABCA1 APOA1 APOA2 APOA5 APOE
23 high-density lipoprotein particle clearance GO:0034384 9.76 APOA1 APOA2 APOE
24 neuron projection regeneration GO:0031102 9.75 APOA1 APOA5 APOE
25 regulation of Cdc42 protein signal transduction GO:0032489 9.73 ABCA1 APOA1 APOE
26 lipoxygenase pathway GO:0019372 9.72 ALOX15 PON1
27 cellular response to cholesterol GO:0071397 9.72 ABCA1 LRP6
28 positive regulation of fatty acid biosynthetic process GO:0045723 9.72 APOA1 APOA5
29 regulation of intestinal cholesterol absorption GO:0030300 9.72 APOA1 APOA2 APOA5
30 positive regulation of lipoprotein lipase activity GO:0051006 9.71 APOA1 APOA5
31 phospholipid homeostasis GO:0055091 9.71 ABCA1 APOA1
32 intestinal cholesterol absorption GO:0030299 9.71 ABCG5 ABCG8
33 positive regulation of triglyceride catabolic process GO:0010898 9.71 APOA1 APOA5
34 chylomicron remnant clearance GO:0034382 9.7 APOB APOE
35 very-low-density lipoprotein particle remodeling GO:0034372 9.7 APOE LCAT
36 positive regulation of lipid catabolic process GO:0050996 9.7 APOA2 APOA5
37 negative regulation of cytokine secretion involved in immune response GO:0002740 9.7 APOA1 APOA2
38 peptidyl-methionine modification GO:0018206 9.69 APOA1 APOA2
39 very-low-density lipoprotein particle clearance GO:0034447 9.69 APOB APOE
40 negative regulation of lipase activity GO:0060192 9.68 APOA1 APOA2
41 lipoprotein catabolic process GO:0042159 9.68 APOB APOE
42 protein oxidation GO:0018158 9.67 APOA1 APOA2
43 negative regulation of very-low-density lipoprotein particle remodeling GO:0010903 9.67 APOA1 APOA2
44 triglyceride-rich lipoprotein particle remodeling GO:0034370 9.66 APOA2 APOA5
45 regulation of high-density lipoprotein particle assembly GO:0090107 9.65 ABCA1 LCAT
46 negative regulation of intestinal cholesterol absorption GO:0045796 9.65 ABCG5 ABCG8
47 negative regulation of intestinal phytosterol absorption GO:0010949 9.65 ABCG5 ABCG8
48 lipoprotein biosynthetic process GO:0042158 9.65 ABCA1 APOA1 APOB APOE LCAT
49 reverse cholesterol transport GO:0043691 9.63 ABCA1 APOA1 APOA2 APOA5 APOE LCAT
50 cholesterol homeostasis GO:0042632 9.61 ABCA1 ABCG5 ABCG8 APOA1 APOA2 APOA5

Molecular functions related to Artery Disease according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 protein heterodimerization activity GO:0046982 9.97 ABCG5 ABCG8 APOA2 ITGA2 MEF2A
2 lipid binding GO:0008289 9.85 ALOX15 APOA1 APOA2 APOA5 APOB APOE
3 ATPase activity, coupled to transmembrane movement of substances GO:0042626 9.69 ABCA1 ABCG5 ABCG8
4 cholesterol binding GO:0015485 9.65 ABCA1 APOA1 APOA2 APOA5 APOE
5 lipid transporter activity GO:0005319 9.62 APOA1 APOA2 APOB APOE
6 phosphatidylcholine binding GO:0031210 9.61 APOA1 APOA2 APOA5
7 apolipoprotein binding GO:0034185 9.59 ABCA1 LRP6
8 phospholipid transporter activity GO:0005548 9.58 ABCA1 APOA1
9 low-density lipoprotein particle receptor binding GO:0050750 9.58 APOA5 APOB APOE
10 high-density lipoprotein particle binding GO:0008035 9.57 APOA1 APOA2
11 beta-amyloid binding GO:0001540 9.56 APOA1 APOE
12 lipase binding GO:0035473 9.55 APOA5 APOB
13 lipase inhibitor activity GO:0055102 9.54 APOA1 APOA2
14 lipoprotein particle binding GO:0071813 9.52 APOA1 APOE
15 phospholipid binding GO:0005543 9.5 ABCA1 APOA1 APOA2 APOA5 APOB APOE
16 apolipoprotein A-I binding GO:0034186 9.49 ABCA1 LCAT
17 high-density lipoprotein particle receptor binding GO:0070653 9.48 APOA1 APOA2
18 apolipoprotein receptor binding GO:0034190 9.46 APOA1 APOA2
19 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.46 APOA1 APOA2 APOA5 APOE
20 cholesterol transporter activity GO:0017127 9.23 ABCA1 ABCG5 ABCG8 APOA1 APOA2 APOA5

Sources for Artery Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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