MCID: ART006
MIFTS: 36

Arthus Reaction malady

Skin diseases, Immune diseases categories

Aliases & Classifications for Arthus Reaction

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 29ICD9CM, 59SNOMED-CT, 42NCIt
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Aliases & Descriptions for Arthus Reaction:

Name: Arthus Reaction 10 47 12 65 36
Arthus Type Urticaria 10
 
Arthus Phenomenon 10


Classifications:



External Ids:

Disease Ontology10 DOID:1556
ICD9CM29 995.21
SNOMED-CT59 29548007, 402413008
MeSH36 D001183
NCIt42 C34400

Summaries for Arthus Reaction

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Wikipedia:68 In immunology, the Arthus reaction (/ˌɑrˈtuːs/, /ˌɑrˈtjuːs/) is a type of local type III... more...

MalaCards based summary: Arthus Reaction, also known as arthus type urticaria, is related to asthma and vasculitis. An important gene associated with Arthus Reaction is SELL (Selectin L), and among its related pathways are LDL Oxidation in Atherogenesis and African trypanosomiasis. Affiliated tissues include skin, neutrophil and testes, and related mouse phenotypes are tumorigenesis and hematopoietic system.

Related Diseases for Arthus Reaction

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Diseases related to Arthus Reaction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1asthma29.6ALOX5, ELANE, ICAM1, SELL, TNF
2vasculitis10.4
3hepatitis10.3
4hepatitis b10.3
5thrombocytopenia10.3
6peritonitis10.3
7tuberculous uveitis10.2ALOX5, TNF
8moderately severe hemophilia a10.2HMOX1, TNF
9arthritis10.2
10glomerulonephritis10.2
11shwartzman phenomenon10.2
12diphtheria10.2
13encephalitis10.2
14eosinophilia10.2
15pertussis10.2
16pleurisy10.2
17pneumonia10.2
18thyroiditis10.2
19leiomyoma10.2CR1, TNF
20pustulosis palmaris et plantaris10.2ELANE, TNF
2146 xx gonadal dysgenesis10.2ELANE, TNF
22tooth ankylosis10.2ELANE, TNF
23liver lymphoma10.2HMOX1, TNF
24granulomas, congenital cerebral10.2SELL, TNF
25pyknoachondrogenesis10.2ELANE, TNF
26acute zonal occult outer retinopathy10.1ELANE, TNF
27congenital cataract - progressive muscular hypotonia - hearing loss - developmental delay10.1ICAM1, TNF
28rhizomelic dysplasia patterson lowry type10.1ICAM1, TNF
29adult t-cell leukemia10.1ELANE, TNF
30polycythemia10.1ICAM1, TNF
31lip cancer10.1ICAM1, TNF
32powassan encephalitis10.1ICAM1, TNF
33dawson disease10.1ICAM1, TNF
34glioblastoma multiforme10.1ELANE, TNF
35alopecia universalis10.1ICAM1, TNF
36breast fibroadenosis10.1ICAM1, TNF
37herpangina10.1ICAM1, TNF
38distal biliary tract carcinoma10.1ICAM1, TNF
39bartholin's duct cyst10.1ICAM1, TNF
40hemorrhoid10.1ICAM1, TNF
41mixed cerebral palsy10.1ELANE, TNF
42non-syndromic x-linked intellectual disability10.1ICAM1, TNF
43pulmonary fibrosis10.1ELANE, HMOX1
44cervical adenoid basal carcinoma10.1ICAM1, TNF
45burn scar10.1ELANE, SELL
46meningovascular neurosyphilis10.1ICAM1, SELL
47alopecia areata10.1ICAM1, TNF
48lumbosacral plexus lesion10.1ICAM1, SELL
49anal paget's disease10.1ELANE, ICAM1
50renal oncocytoma10.1ICAM1, TNF

Graphical network of the top 20 diseases related to Arthus Reaction:



Diseases related to arthus reaction

Symptoms for Arthus Reaction

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Drugs & Therapeutics for Arthus Reaction

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Arthus Reaction


Cochrane evidence based reviews: Arthus Reaction

Genetic Tests for Arthus Reaction

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Anatomical Context for Arthus Reaction

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MalaCards organs/tissues related to Arthus Reaction:

33
Skin, Neutrophil, Testes, Skeletal muscle, Lung, Tongue, Eye

Animal Models for Arthus Reaction or affiliated genes

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MGI Mouse Phenotypes related to Arthus Reaction:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.3ELANE, ICAM1, SELL, TNF
2MP:00053977.5ALOX5, ELANE, HMOX1, ICAM1, SELL, TNF
3MP:00053877.2ALOX5, ELANE, HMOX1, ICAM1, SELL, TNF

Publications for Arthus Reaction

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Articles related to Arthus Reaction:

(show top 50)    (show all 156)
idTitleAuthorsYear
1
Diagnosis of Mesobuthus eupeus envenomation by skin test: Reverse passive Arthus reaction. (24269785)
2014
2
Metabolomic investigation of Arthus reaction in a rat model using proton nuclear magnetic resonance (1H NMR) spectroscopy and rapid resolution liquid chromatography (RRLC). (23511749)
2013
3
Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive arthus reaction. (19389931)
2009
4
Migration inhibitory factor (MIF) released by macrophages upon recognition of immune complexes is critical to inflammation in Arthus reaction. (19188484)
2009
5
Effects of cholinotropic and cytostatic drugs on the development of Arthus reaction. (19513373)
2008
6
Nicotine-induced inflammatory decreasing effect on passive skin arthus reaction in paraventricular nucleus-lesioned wistar rats. (12753427)
2003
7
A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction. (10623857)
2000
8
Erythrogenic toxin-induced arteritis in a rabbit ear model. Comparison with Arthus reaction angiitis. (9331774)
1997
9
Histochemical investigations of the skeletal muscle fibres during the reversed passive Arthus reaction in guinea pigs. (9151106)
1997
10
Light and electron microscopic examination of skeletal muscles in the reversed passive Arthus reaction. (9278109)
1997
11
Role of P-selectin in the early stage of the Arthus reaction. (8886860)
1996
12
The role of ICAM-1 in the reverse passive Arthus reaction induced pleurisy in the rat. (8548405)
1995
13
Neutrophil elicitation in the reverse passive Arthus reaction. Complement-dependent and -independent mast cell involvement. (8301139)
1994
14
Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. (8066448)
1994
15
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. (8242264)
1993
16
Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction. (8228810)
1993
17
Suppression of the Arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor. (1388318)
1992
18
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction. (1330163)
1992
19
Serotonin metabolism in the arthus reaction. (2136904)
1990
20
Biological and immunological properties of Sugi basic protein-pullulan conjugate. II. Is the reduced ability to elicit the Arthus reaction based on the poor activation of complement by immune complex consisting of anti-Sugi basic protein and Sugi basic protein-pullulan? (2138137)
1990
21
The Arthus reaction in domestic cats. (2969157)
1988
22
Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. (2968048)
1988
23
Impaired histamine metabolism in the Arthus reaction induced in guinea-pig skin. (3159351)
1985
24
Effects of PGF2 alpha on the active Arthus reaction in rat and rabbit tongues. (3161844)
1985
25
Immune complexes and inflammation. A study of the activity of anti-inflammatory drugs in the reverse passive arthus reaction in the rat. (6221727)
1983
26
Modification of two models of Arthus reaction in the rat by various drugs. (6460508)
1982
27
The effects of anti-inflammatory and other agents on the rat dermal arthus reaction. (6122238)
1982
28
Effects of dapsone on passive Arthus reaction and chemotaxis and phagocytosis of polymorphonuclear leukocytes. (6455972)
1981
29
Transient immune deposits in the papillary dermis and in the epidermis. A light-microscopical study on the experimental Arthus reaction. (6449910)
1980
30
The Arthus reaction in rats, a possible test for anti-inflammatory and antiheumatic drugs. (157676)
1979
31
The effect of sulphinpyrazone and other drugs on the platelet response during the acute phase of the active Arthus reaction in guinea pigs. (158844)
1979
32
Lepromin and the Arthus reaction. (147247)
1977
33
The effect of shock on the inflammatory response. A reevaluation of the role of platelets in the active arthus reaction. (122800)
1975
34
Ultrastructural evidence for lack of tissue damage in a local immune complex reaction: a study of a mild passive Arthus reaction. (125484)
1975
35
Gastrointestinal ulcer--arthus reaction. (4273310)
1974
36
The early changes in the Arthus reaction in the rabbit oral mucosa. (4280437)
1974
37
The requirement for platelets in the active Arthus reaction. (4258952)
1971
38
Effects of neutrophils on tissues. Experiments on the Arthus reaction, the flare phenomenon, and post-phagocytic release of lysosomal enzymes. (4243806)
1969
39
Adrenal medullary hormones and phenothiazine: effects on the Arthus reaction in adult rabbits. (4389807)
1969
40
Leukoegresin: a factor from rabbit skin associated with leucocytic emigration in the Arthus reaction. (4234575)
1968
41
The Arthus reaction to Candida albicans in asthma patients. (4237283)
1968
42
Inhibitory effect of large doses of histamine on the passive Arthus reaction. (4225450)
1967
43
Hyperacute encephalitis resembling the Arthus-reaction. (4239964)
1966
44
ARTHUS REACTION IN THE ORAL CAVITY OF LABORATORY ANIMALS. (14248775)
1965
45
Fluorescent protein tracer studies in allergic reactions. I. The fate of fluorescent antigen in active and passive Arthus reaction in the guinea-pig skin. (14482093)
1961
46
Prevention by intravenous injection of antigen and antibody of passive Arthus reaction to unrelated immune system. (13675297)
1959
47
Observations on the histology of the Arthus reaction and its relation to other known types of skin hypersensitivity. (13142698)
1954
48
Quantitative study of Arthus reaction and of cutaneous anaphylaxis induced passively in the rat. (13037728)
1952
49
Effect of 17-hydroxy-11-dehydrocorticosterone (compound E) and of ACTH on arthus reaction and antibody formation in the rabbit. (14781192)
1950
50
Effect of salicylate and tripelennamine hydrochloride (pyribenzamine) on the Arthus reaction and on bacterial allergic reactions. (18900017)
1947

Variations for Arthus Reaction

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Expression for genes affiliated with Arthus Reaction

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Search GEO for disease gene expression data for Arthus Reaction.

Pathways for genes affiliated with Arthus Reaction

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GO Terms for genes affiliated with Arthus Reaction

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Cellular components related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.7ICAM1, SELL, TNF
2integral component of plasma membraneGO:00058878.2CD46, CR1, ICAM1, SELL, TNF
3extracellular spaceGO:00056157.9ALOX5, ELANE, HMOX1, ICAM1, TNF
4cell surfaceGO:00099867.0CD46, CR1, ELANE, ICAM1, SELL, TNF

Biological processes related to Arthus Reaction according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1response to hyperoxiaGO:005509310.2ALOX5, SELL
2positive regulation of chemokine biosynthetic processGO:004508010.1HMOX1, TNF
3negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204210.0HMOX1, ICAM1
4positive regulation of vasoconstrictionGO:00459079.9ALOX5, ICAM1
5intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.9HMOX1, TNF
6positive regulation of interleukin-8 biosynthetic processGO:00454169.8ELANE, TNF
7acute inflammatory response to antigenic stimulusGO:00024389.8ELANE, ICAM1
8regulation of complement activationGO:00304499.8CD46, CR1
9positive regulation of nitric oxide biosynthetic processGO:00454299.8ICAM1, TNF
10complement activation, classical pathwayGO:00069589.7CD46, CR1
11negative regulation of growth of symbiont in hostGO:00441309.6ELANE, TNF
12positive regulation of MAP kinase activityGO:00434069.5ELANE, TNF
13viral entry into host cellGO:00467189.2CD46, CR1, ICAM1
14positive regulation of smooth muscle cell proliferationGO:00486619.0ELANE, HMOX1, TNF
15extracellular matrix organizationGO:00301988.8ELANE, ICAM1, TNF
16leukocyte migrationGO:00509008.7ELANE, ICAM1, SELL, TNF

Molecular functions related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020208.9ELANE, SELL, TNF
2virus receptor activityGO:00016188.9CD46, CR1, ICAM1

Sources for Arthus Reaction

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet