Aliases & Classifications for Arthus Reaction

About this section

Aliases & Descriptions for Arthus Reaction:

Name: Arthus Reaction 11 50 39 13 68
Arthus Type Urticaria 11
 
Arthus Phenomenon 11

Classifications:



External Ids:

Disease Ontology11 DOID:1556
ICD1030 T78.41
ICD9CM32 995.21
SNOMED-CT62 29548007, 402413008
MeSH39 D001183
NCIt45 C34400

Summaries for Arthus Reaction

About this section
Wikipedia:71 In immunology, the Arthus reaction (/ˌɑːrˈtuːs/, /ˌɑːrˈtjuːs/) is a type of local type III... more...

MalaCards based summary: Arthus Reaction, also known as arthus type urticaria, is related to shwartzman phenomenon and asthma, and has symptoms including other urticaria and welts. An important gene associated with Arthus Reaction is SELL (Selectin L), and among its related pathways are African trypanosomiasis and LDL Oxidation in Atherogenesis. Affiliated tissues include skin, neutrophil and testes, and related mouse phenotypes are neoplasm and cardiovascular system.

Related Diseases for Arthus Reaction

About this section

Diseases related to Arthus Reaction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1shwartzman phenomenon30.3ICAM1, SELL
2asthma28.7ALOX5, ELANE, ICAM1, SELL, TNF
3granulomatous hypophysitis10.5SELL, TNF
4acute dacryocystitis10.5ICAM1, SELL
5chromophobe adenoma10.5ICAM1, SELL
6rhizomelic pseudopolyarthritis10.5ICAM1, TNF
7oppositional defiant disorder10.5ICAM1, SELL
8spastic paraplegia-paget disease of bone syndrome10.5ICAM1, TNF
9meninges hemangiopericytoma10.5ICAM1, TNF
10atrichia with papular lesions10.4ICAM1, TNF
11bolivian hemorrhagic fever10.4ICAM1, TNF
12malignant histiocytosis10.4ICAM1, TNF
13psychosexual disorder10.4ICAM1, SELL
14labyrinthine bilateral reactive loss10.4ICAM1, TNF
15t-cell lymphoma 1a10.4ALOX5, TNF
16dentin dysplasia10.4ICAM1, TNF
17dementia - subcortical10.4ICAM1, TNF
18hypospadias10.4ICAM1, TNF
19geotrichosis10.4ICAM1, TNF
20alopecia10.3ICAM1, TNF
21meibomian cyst10.3ELANE, SELL
22brucella abortus brucellosis10.3ELANE, TNF
23lemierre's syndrome10.3ELANE, TNF
24wissler's syndrome10.3ICAM1, TNF
25mycobacterium fortuitum10.3HMOX1, TNF
26biliary tract disease10.3ICAM1, TNF
27idiopathic central precocious puberty10.3HMOX1, TNF
28loin pain hematuria syndrome10.3ELANE, TNF
29ataxias and cerebellar or spinocerebellar degeneration10.3ICAM1, NOS2
30toxic maculopathy10.2ICAM1, TNF
31louping ill10.2ICAM1, SELL, TNF
32elane-related neutropenia10.2NOS2, TNF
33qualitative platelet defect10.2NOS2, TNF
34scn8a encephalopathy10.2NOS2, TNF
35exophthalmos10.2ICAM1, TNF
36neonatal period electroclinical syndrome10.2ELANE, TNF
37vertebral artery insufficiency10.2NOS2, TNF
38leukoplakia10.1NOS2, TNF
39alcohol abuse10.1ELANE, TNF
40ehlers-danlos syndrome, musculocontractural type10.1NOS2, TNF
41nervous system cancer10.1ELANE, TNF
42vestibular nystagmus10.1CR1, ICAM1, TNF
43malakoplakia10.1CR1, NOS2
44renal tubular acidosis10.1ICAM1, TNF
45idiopathic interstitial pneumonia10.1ICAM1, TNF
46pulmonary sarcoidosis10.1ELANE, HMOX1
47loeffler syndrome10.1ELANE, TNF
48hyperuricemia, pulmonary hypertension, renal failure, and alkalosis10.1ELANE, SELL, TNF
49chronic myocardial ischemia10.0ICAM1, SELL, TNF
50laryngeal tuberculosis10.0ELANE, ICAM1, TNF

Graphical network of the top 20 diseases related to Arthus Reaction:



Diseases related to arthus reaction

Symptoms & Phenotypes for Arthus Reaction

About this section

UMLS symptoms related to Arthus Reaction:


other urticaria, welts

MGI Mouse Phenotypes related to Arthus Reaction according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.3ELANE, ICAM1, NOS2, SELL, TNF
2MP:00053858.1ALOX5, CD46, HMOX1, ICAM1, NOS2, SELL
3MP:00053977.9ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL
4MP:00053767.8ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL
5MP:00053877.8ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL

Drugs & Therapeutics for Arthus Reaction

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Arthus Reaction


Cochrane evidence based reviews: arthus reaction

Genetic Tests for Arthus Reaction

About this section

Anatomical Context for Arthus Reaction

About this section

MalaCards organs/tissues related to Arthus Reaction:

36
Skin, Neutrophil, Testes, Skeletal muscle, Lung, Tongue, Eye

Publications for Arthus Reaction

About this section

Articles related to Arthus Reaction:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Anti-TWEAK monoclonal antibodies reduce vascular damage and leucocyte infiltration in a mouse model of cutaneous reverse passive Arthus reaction. (27753135)
2016
2
Diagnosis of Mesobuthus eupeus envenomation by skin test: Reverse passive Arthus reaction. (24269785)
2014
3
Exogenous application of hydrogen sulfide donor attenuates inflammatory reactions through the L-selectin-involved pathway in the cutaneous reverse passive Arthus reaction. (23381473)
2013
4
Metabolomic investigation of Arthus reaction in a rat model using proton nuclear magnetic resonance (1H NMR) spectroscopy and rapid resolution liquid chromatography (RRLC). (23511749)
2013
5
Paeoniflorin suppresses vascular damage and the expression of E-selectin and ICAM-1 in a mouse model of cutaneous Arthus reaction. (23800055)
2013
6
Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model. (23096126)
2013
7
Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction. (22784785)
2012
8
Platelets control leukocyte recruitment in a murine model of cutaneous arthus reaction. (20008131)
2010
9
Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive arthus reaction. (19389931)
2009
10
Migration inhibitory factor (MIF) released by macrophages upon recognition of immune complexes is critical to inflammation in Arthus reaction. (19188484)
2009
11
Effects of cholinotropic and cytostatic drugs on the development of Arthus reaction. (19513373)
2008
12
Involvement of gaseous low molecular monoxides in the cutaneous reverse passive Arthus reaction: cytoprotective action of carbon monoxide. (18505425)
2008
13
Intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 cooperatively contribute to the cutaneous Arthus reaction. (17299025)
2007
14
Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation. (15728518)
2005
15
Role of C-C chemokine receptors 1 and 5 and CCL3/macrophage inflammatory protein-1alpha in the cutaneous Arthus reaction: possible attenuation of their inhibitory effects by compensatory chemokine production. (15517609)
2004
16
Effect of nicotine-induced corticosterone elevation on nitric oxide production in the passive skin arthus reaction in rats. (14745115)
2004
17
Nicotine-induced inflammatory decreasing effect on passive skin arthus reaction in paraventricular nucleus-lesioned wistar rats. (12753427)
2003
18
New functions of neutrophils in the arthus reaction: expression of tissue factor, the clotting initiator, and fibrinolysis by elastase. (12379763)
2002
19
Arthus reaction to lepirudin, a new recombinant hirudin, and delayed-type hypersensitivity to several heparins and heparinoids, with tolerance to its intravenous administration. (11918584)
2002
20
The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. (11884469)
2002
21
Apoptosis mediates decrease in cellularity during the regression of Arthus reaction in cornea. (11316727)
2001
22
Lyn is essential for fcgamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction. (11238587)
2001
23
Transcription factor decoy oligodeoxynucleotides to nuclear factor-kappaB inhibit reverse passive Arthus reaction in rat. (11692225)
2001
24
Arthus reaction to recombinant hepatitis B virus vaccine. (11512098)
2001
25
A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction. (10623857)
2000
26
Contribution of B(2) receptors for bradykinin in arthus reaction-induced plasma extravasation in wild-type or B(2) transgenic knockout mice. (10780980)
2000
27
A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats. (10843715)
2000
28
The Arthus reaction in rodents: species-specific requirement of complement. (10605043)
2000
29
On the role of complement and Fc gamma-receptors in the Arthus reaction. (10698344)
1999
30
Nitric oxide inhibits neutrophil infiltration in the reverse passive arthus reaction in rat skin. (9826072)
1998
31
Streptococcal and staphylococcal superantigen-induced lymphocytic arteritis in a local type experimental model: comparison with acute vasculitis in the Arthus reaction. (9452132)
1998
32
Roles of endothelins and their receptors in immune complex-induced/polymorphonuclear-mediated lung injury (reversed passive arthus reaction) in CD-1 mice. (9918750)
1998
33
In vivo inflammatory response to a prototypic B cell superantigen: elicitation of an Arthus reaction by staphylococcal protein A. (9605120)
1998
34
P-selectin requirement for neutrophil accumulation and injury in the direct passive Arthus reaction. (9649192)
1998
35
Histochemical investigations of the skeletal muscle fibres during the reversed passive Arthus reaction in guinea pigs. (9151106)
1997
36
Erythrogenic toxin-induced arteritis in a rabbit ear model. Comparison with Arthus reaction angiitis. (9331774)
1997
37
Light and electron microscopic examination of skeletal muscles in the reversed passive Arthus reaction. (9278109)
1997
38
Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor. (9271590)
1997
39
ICAM-1 mediates leukocyte-endothelium adhesive interactions in the reversed passive Arthus reaction. (8604010)
1996
40
Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. (8769481)
1996
41
Role of P-selectin in the early stage of the Arthus reaction. (8886860)
1996
42
A dominant role for mast cell Fc receptors in the Arthus reaction. (8885871)
1996
43
The role of CD11/CD18 integrins in the reverse passive Arthus reaction in rat dermal tissue. (8603998)
1996
44
The role of ICAM-1 in the reverse passive Arthus reaction induced pleurisy in the rat. (8548405)
1995
45
Studies on the mechanisms involved in the inflammatory response in a reversed passive Arthus reaction in guinea-pig skin: contribution of neutrophils and endogenous mediators. (7889293)
1994
46
Neutrophil elicitation in the reverse passive Arthus reaction. Complement-dependent and -independent mast cell involvement. (8301139)
1994
47
Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. (8066448)
1994
48
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. (8242264)
1993
49
Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction. (8228810)
1993
50
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction. (1330163)
1992

Variations for Arthus Reaction

About this section

Expression for genes affiliated with Arthus Reaction

About this section
Search GEO for disease gene expression data for Arthus Reaction.

Pathways for genes affiliated with Arthus Reaction

About this section

GO Terms for genes affiliated with Arthus Reaction

About this section

Cellular components related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:000989710.2ICAM1, SELL, TNF
2extracellular spaceGO:00056158.6ALOX5, ELANE, HMOX1, ICAM1, TNF
3cell surfaceGO:00099868.6CD46, CR1, ELANE, ICAM1, SELL, TNF
4integral component of plasma membraneGO:00058878.5CD46, CR1, ICAM1, SELL, TNF

Biological processes related to Arthus Reaction according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of nitric oxide biosynthetic processGO:004542910.4ICAM1, TNF
2positive regulation of vasoconstrictionGO:004590710.4ALOX5, ICAM1
3acute inflammatory response to antigenic stimulusGO:000243810.2ELANE, ICAM1
4negative regulation of growth of symbiont in hostGO:004413010.2ELANE, TNF
5positive regulation of interleukin-8 biosynthetic processGO:004541610.2ELANE, TNF
6regulation of complement activationGO:003044910.1CD46, CR1
7negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204210.0HMOX1, ICAM1
8intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.0HMOX1, TNF
9positive regulation of chemokine biosynthetic processGO:004508010.0HMOX1, TNF
10cellular response to lipopolysaccharideGO:00712229.9ICAM1, NOS2, TNF
11negative regulation of gene expressionGO:00106299.8CD46, NOS2, TNF
12positive regulation of vasodilationGO:00459099.8HMOX1, NOS2
13defense response to bacteriumGO:00427429.7ELANE, NOS2, TNF
14leukocyte migrationGO:00509009.5ELANE, ICAM1, SELL, TNF
15response to lipopolysaccharideGO:00324969.5ELANE, ICAM1, NOS2
16response to hypoxiaGO:00016669.4HMOX1, ICAM1, NOS2
17positive regulation of smooth muscle cell proliferationGO:00486619.3ELANE, HMOX1, TNF
18viral entry into host cellGO:00467189.2CD46, CR1, ICAM1

Molecular functions related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.6ELANE, SELL, TNF
2virus receptor activityGO:00016189.2CD46, CR1, ICAM1

Sources for Arthus Reaction

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet