MCID: ART006
MIFTS: 38

Arthus Reaction malady

Category: Immune diseases

Aliases & Classifications for Arthus Reaction

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Aliases & Descriptions for Arthus Reaction:

Name: Arthus Reaction 11 49 38 13 67
Arthus Type Urticaria 11
 
Arthus Phenomenon 11

Classifications:



External Ids:

Disease Ontology11 DOID:1556
ICD1029 T78.41
ICD9CM31 995.21
SNOMED-CT61 29548007, 402413008
MeSH38 D001183
NCIt44 C34400

Summaries for Arthus Reaction

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Wikipedia:70 In immunology, the Arthus reaction (/ˌɑːrˈtuːs/, /ˌɑːrˈtjuːs/) is a type of local type III... more...

MalaCards based summary: Arthus Reaction, also known as arthus type urticaria, is related to shwartzman phenomenon and asthma, and has symptoms including other urticaria and welts. An important gene associated with Arthus Reaction is SELL (Selectin L), and among its related pathways are African trypanosomiasis and LDL Oxidation in Atherogenesis. Affiliated tissues include skin, neutrophil and testes, and related mouse phenotypes are neoplasm and cardiovascular system.

Related Diseases for Arthus Reaction

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Diseases related to Arthus Reaction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1shwartzman phenomenon30.3ICAM1, SELL
2asthma28.7ALOX5, ELANE, ICAM1, SELL, TNF
3granulomatous hypophysitis10.5SELL, TNF
4acute dacryocystitis10.5ICAM1, SELL
5chromophobe adenoma10.5ICAM1, SELL
6rhizomelic pseudopolyarthritis10.5ICAM1, TNF
7oppositional defiant disorder10.5ICAM1, SELL
8spastic paraplegia-paget disease of bone syndrome10.5ICAM1, TNF
9meninges hemangiopericytoma10.5ICAM1, TNF
10atrichia with papular lesions10.4ICAM1, TNF
11bolivian hemorrhagic fever10.4ICAM1, TNF
12malignant histiocytosis10.4ICAM1, TNF
13psychosexual disorder10.4ICAM1, SELL
14labyrinthine bilateral reactive loss10.4ICAM1, TNF
15t-cell lymphoma 1a10.4ALOX5, TNF
16dentin dysplasia10.4ICAM1, TNF
17dementia - subcortical10.4ICAM1, TNF
18hypospadias10.4ICAM1, TNF
19geotrichosis10.4ICAM1, TNF
20alopecia10.3ICAM1, TNF
21meibomian cyst10.3ELANE, SELL
22brucella abortus brucellosis10.3ELANE, TNF
23lemierre's syndrome10.3ELANE, TNF
24wissler's syndrome10.3ICAM1, TNF
25mycobacterium fortuitum10.3HMOX1, TNF
26biliary tract disease10.3ICAM1, TNF
27idiopathic central precocious puberty10.3HMOX1, TNF
28loin pain hematuria syndrome10.3ELANE, TNF
29ataxias and cerebellar or spinocerebellar degeneration10.3ICAM1, NOS2
30toxic maculopathy10.2ICAM1, TNF
31louping ill10.2ICAM1, SELL, TNF
32elane-related neutropenia10.2NOS2, TNF
33qualitative platelet defect10.2NOS2, TNF
34scn8a encephalopathy10.2NOS2, TNF
35exophthalmos10.2ICAM1, TNF
36neonatal period electroclinical syndrome10.2ELANE, TNF
37vertebral artery insufficiency10.2NOS2, TNF
38leukoplakia10.1NOS2, TNF
39alcohol abuse10.1ELANE, TNF
40ehlers-danlos syndrome, musculocontractural type10.1NOS2, TNF
41nervous system cancer10.1ELANE, TNF
42vestibular nystagmus10.1CR1, ICAM1, TNF
43malakoplakia10.1CR1, NOS2
44renal tubular acidosis10.1ICAM1, TNF
45idiopathic interstitial pneumonia10.1ICAM1, TNF
46pulmonary sarcoidosis10.1ELANE, HMOX1
47loeffler syndrome10.1ELANE, TNF
48hyperuricemia, pulmonary hypertension, renal failure, and alkalosis10.1ELANE, SELL, TNF
49chronic myocardial ischemia10.0ICAM1, SELL, TNF
50laryngeal tuberculosis10.0ELANE, ICAM1, TNF

Graphical network of the top 20 diseases related to Arthus Reaction:



Diseases related to arthus reaction

Symptoms for Arthus Reaction

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UMLS symptoms related to Arthus Reaction:


other urticaria, welts

Drugs & Therapeutics for Arthus Reaction

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Arthus Reaction


Cochrane evidence based reviews: arthus reaction

Genetic Tests for Arthus Reaction

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Anatomical Context for Arthus Reaction

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MalaCards organs/tissues related to Arthus Reaction:

35
Skin, Neutrophil, Testes, Skeletal muscle, Lung, Tongue, Eye

Animal Models for Arthus Reaction or affiliated genes

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MGI Mouse Phenotypes related to Arthus Reaction:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.3ELANE, ICAM1, NOS2, SELL, TNF
2MP:00053858.1ALOX5, CD46, HMOX1, ICAM1, NOS2, SELL
3MP:00053977.9ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL
4MP:00053767.8ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL
5MP:00053877.8ALOX5, ELANE, HMOX1, ICAM1, NOS2, SELL

Publications for Arthus Reaction

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Articles related to Arthus Reaction:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Effects of cholinotropic and cytostatic drugs on the development of Arthus reaction. (19513373)
2008
2
Involvement of gaseous low molecular monoxides in the cutaneous reverse passive Arthus reaction: cytoprotective action of carbon monoxide. (18505425)
2008
3
A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction. (10623857)
2000
4
On the role of complement and Fc gamma-receptors in the Arthus reaction. (10698344)
1999
5
Histochemical investigations of the skeletal muscle fibres during the reversed passive Arthus reaction in guinea pigs. (9151106)
1997
6
ICAM-1 mediates leukocyte-endothelium adhesive interactions in the reversed passive Arthus reaction. (8604010)
1996
7
The role of ICAM-1 in the reverse passive Arthus reaction induced pleurisy in the rat. (8548405)
1995
8
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. (8242264)
1993
9
Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction. (8228810)
1993
10
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction. (1330163)
1992
11
Suppression of vascular injury at the Arthus reaction site by a complement inhibitor, 5,5',5''-(1,3,6-naphthalene-triyl-tris[sulfonylimino])-tris (1,3-benzene disulfonic acid) hexasodium salt. (1828755)
1991
12
Serotonin metabolism in the arthus reaction. (2136904)
1990
13
Skin necrosis after injection of aminosides. Arthus reaction, local toxicity, thrombotic process or pathergy? (2141580)
1990
14
Inhibition of cellular infiltration at the site of Arthus reaction by chlorpromazine. Use of a new area integration technique. (2148738)
1990
15
The Arthus reaction in cats deficient in Hageman factor (factor XII). (2138171)
1990
16
Enhancement of the Arthus reaction and suppression of delayed type hypersensitivity (DTH) by pluronic F-68, a detergent frequently used to prepare perfluorocarbon emulsions. (2525535)
1989
17
The Arthus reaction in domestic cats. (2969157)
1988
18
Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. (2968048)
1988
19
Biogenic amines in the Arthus reaction. (2958359)
1987
20
Histamine metabolism in the Arthus reaction. (2936618)
1986
21
A specific antagonist of platelet-activating factor suppresses oedema formation in an Arthus reaction but not oedema induced by leukocyte chemoattractants in rabbit skin. (2940300)
1986
22
Impaired histamine metabolism in the Arthus reaction induced in guinea-pig skin. (3159351)
1985
23
Effects of PGF2 alpha on the active Arthus reaction in rat and rabbit tongues. (3161844)
1985
24
Ex vivo effects of nonsteroidal antiinflammatory drugs on arachidonic acid metabolism in neutrophils from a reverse passive Arthus reaction. (3156814)
1985
25
Studies on the role of polymorphonuclear leukocyte granule elastase in Arthus reaction. (6240230)
1984
26
Immune complexes and inflammation. A study of the activity of anti-inflammatory drugs in the reverse passive arthus reaction in the rat. (6221727)
1983
27
Pathways to inflammation induced by immune complexes: development of the Arthus reaction. (6211371)
1982
28
Transient immune deposits in the papillary dermis and in the epidermis. A light-microscopical study on the experimental Arthus reaction. (6449910)
1980
29
Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP. (6452106)
1980
30
Protease inhibitors reduce the reverse passive Arthus reaction. (152568)
1978
31
Distribution of immune deposits in the skin of reversed passive arthus reaction using horseradish peroxidase as antigen. (45717)
1976
32
The effect of shock on the inflammatory response. A reevaluation of the role of platelets in the active arthus reaction. (122800)
1975
33
Mechanism of action of colchicine. I. Effect of colchicine and its analogs on the reversed passive Arthus reaction and the carrageenan-induced hindpaw edema in the rat. (125325)
1975
34
The Arthus reaction in guinea-pig knee joints. A test for anti-inflammatory drugs. (1220555)
1975
35
Delayed hypersensitivity and Arthus reaction to purified hepatitis B surface antigen (HBsAg) in immunized chimpanzees. (128431)
1975
36
Light and immunofluorescent study of the Arthus reaction in the rabbit lung. (128566)
1975
37
Gastrointestinal ulcer--arthus reaction. (4273310)
1974
38
The early changes in the Arthus reaction in the rabbit oral mucosa. (4280437)
1974
39
The papulonecrotic tuberculide. From Arthus reaction to lupus vulgaris. (4279670)
1974
40
Non-hemorrhagic arthus reaction and its independence from circulating antibodies and complement. (4146960)
1973
41
Thyroid eosinophilia and cutaneous Arthus reaction simultaneously induced in the guinea-pig by antiserum to thyroglobulin. (4249611)
1970
42
Effects of neutrophils on tissues. Experiments on the Arthus reaction, the flare phenomenon, and post-phagocytic release of lysosomal enzymes. (4243806)
1969
43
Leukoegresin: a factor from rabbit skin associated with leucocytic emigration in the Arthus reaction. (4234575)
1968
44
The Arthus reaction to Candida albicans in asthma patients. (4237283)
1968
45
Inhibitory effect of large doses of histamine on the passive Arthus reaction. (4225450)
1967
46
The role of PMN-leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. I. The vascular changes and the role of PMN-leukocytes in the reversed passive Arthus reaction. (4225017)
1966
47
Prevention by intravenous injection of antigen and antibody of passive Arthus reaction to unrelated immune system. (13675297)
1959
48
Arthus reaction in the mouse and the rat after intralabial injection of antigens. (13295601)
1956
49
Quantitative study of Arthus reaction and of cutaneous anaphylaxis induced passively in the rat. (13037728)
1952
50
Effect of salicylate and tripelennamine hydrochloride (pyribenzamine) on the Arthus reaction and on bacterial allergic reactions. (18900017)
1947

Variations for Arthus Reaction

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Expression for genes affiliated with Arthus Reaction

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Search GEO for disease gene expression data for Arthus Reaction.

Pathways for genes affiliated with Arthus Reaction

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GO Terms for genes affiliated with Arthus Reaction

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Cellular components related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.7ICAM1, SELL, TNF
2integral component of plasma membraneGO:00058878.5CD46, CR1, ICAM1, SELL, TNF
3cell surfaceGO:00099867.9CD46, CR1, ELANE, ICAM1, SELL, TNF
4extracellular spaceGO:00056157.8ALOX5, ELANE, HMOX1, ICAM1, TNF

Biological processes related to Arthus Reaction according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vasoconstrictionGO:004590710.2ALOX5, ICAM1
2positive regulation of interleukin-8 biosynthetic processGO:004541610.1ELANE, TNF
3regulation of complement activationGO:003044910.0CD46, CR1
4negative regulation of growth of symbiont in hostGO:004413010.0ELANE, TNF
5acute inflammatory response to antigenic stimulusGO:00024389.9ELANE, ICAM1
6positive regulation of nitric oxide biosynthetic processGO:00454299.9ICAM1, TNF
7positive regulation of chemokine biosynthetic processGO:00450809.9HMOX1, TNF
8intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.8HMOX1, TNF
9negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.8HMOX1, ICAM1
10cellular response to lipopolysaccharideGO:00712229.7ICAM1, NOS2, TNF
11positive regulation of vasodilationGO:00459099.7HMOX1, NOS2
12negative regulation of gene expressionGO:00106299.2CD46, NOS2, TNF
13defense response to bacteriumGO:00427429.2ELANE, NOS2, TNF
14response to lipopolysaccharideGO:00324969.2ELANE, ICAM1, NOS2
15positive regulation of smooth muscle cell proliferationGO:00486619.2ELANE, HMOX1, TNF
16viral entry into host cellGO:00467189.1CD46, CR1, ICAM1
17leukocyte migrationGO:00509008.9ELANE, ICAM1, SELL, TNF
18response to hypoxiaGO:00016668.8HMOX1, ICAM1, NOS2

Molecular functions related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.2ELANE, SELL, TNF
2virus receptor activityGO:00016188.9CD46, CR1, ICAM1

Sources for Arthus Reaction

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet