Aliases & Classifications for Arthus Reaction

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Aliases & Descriptions for Arthus Reaction:

Name: Arthus Reaction 11 13 48 37 66
Arthus Type Urticaria 11
 
Arthus Phenomenon 11

Classifications:



External Ids:

Disease Ontology11 DOID:1556
ICD1028 T78.41
ICD9CM30 995.21
SNOMED-CT60 29548007, 402413008
MeSH37 D001183
NCIt43 C34400

Summaries for Arthus Reaction

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Wikipedia:69 In immunology, the Arthus reaction (/ˌɑːrˈtuːs/, /ˌɑːrˈtjuːs/) is a type of local type III... more...

MalaCards based summary: Arthus Reaction, also known as arthus type urticaria, is related to shwartzman phenomenon and diphtheria, and has symptoms including welts and other urticaria. An important gene associated with Arthus Reaction is TNF (Tumor Necrosis Factor), and among its related pathways are LDL Oxidation in Atherogenesis and African trypanosomiasis. Affiliated tissues include skin, neutrophil and testes, and related mouse phenotypes are liver/biliary system and muscle.

Related Diseases for Arthus Reaction

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Diseases related to Arthus Reaction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1shwartzman phenomenon30.0ICAM1, SELL
2diphtheria29.8ALB, TNF
3asthma29.0ALOX5, ICAM1, SELL, TNF
4t-cell lymphoma 1a10.6ALOX5, TNF
5stomatocytosis ii10.6MIF, TNF
6oral candidiasis10.5MIF, TNF
7mycobacterium fortuitum10.5HMOX1, TNF
8idiopathic central precocious puberty10.5HMOX1, TNF
9scrub typhus10.5ALB, TNF
10granulomatous hypophysitis10.5SELL, TNF
11cartilage disease10.5ALB, TNF
12scleral disease10.5ALB, TNF
13pancreatic solid pseudopapillary carcinoma10.5ALB, TNF
14fibrous histiocytoma10.4ALB, TNF
15bardet-biedl syndrome 810.4HMOX1, TNF
16kidney angiomyolipoma10.4ALB, TNF
17benign lymphoepithelial lesion of salivary gland10.4ALB, TNF
18spastic paraplegia-paget disease of bone syndrome10.4ICAM1, TNF
19chronic apical periodontitis10.3ALB, TNF
20meninges hemangiopericytoma10.3ICAM1, TNF
21achilles bursitis10.3ALB, TNF
22atrichia with papular lesions10.3ICAM1, TNF
23bolivian hemorrhagic fever10.3ICAM1, TNF
24malignant histiocytosis10.3ICAM1, TNF
25intestinal variant cervical mucinous adenocarcinoma10.3ALB, TNF
26labyrinthine bilateral reactive loss10.3ICAM1, TNF
27chronic progressive external ophthalmoplegia10.3ALB, HMOX1
28sarcoid meningitis10.3ALB, TNF
29dentin dysplasia10.3ICAM1, TNF
30dementia - subcortical10.3ICAM1, TNF
31hypospadias10.3ICAM1, TNF
32hepatic coma10.3ALB, TNF
33cutaneous porphyria10.3ALB, TNF
34neurogenic bowel10.3ALB, TNF
35geotrichosis10.3ICAM1, TNF
36proximal symphalangism10.3ICAM1, TNF
37intracranial primitive neuroectodermal tumor10.2ALB, ICAM1
38elane-related neutropenia10.2NOS2, TNF
39amyotrophic lateral sclerosis type 410.2NOS2, TNF
40acute dacryocystitis10.2ICAM1, SELL
41chromoblastomycosis10.2ALB, ICAM1
42qualitative platelet defect10.2NOS2, TNF
43amelogenesis imperfecta10.2ALB, TNF
44chromophobe adenoma10.1ICAM1, SELL
45scn8a encephalopathy10.1NOS2, TNF
46oppositional defiant disorder10.1ICAM1, SELL
47granuloma annulare10.1ALB, CR1, TNF
48gastric ulcer10.1ALB, TNF
49vertebral artery insufficiency10.1NOS2, TNF
50pulpitis10.1ALB, HMOX1

Graphical network of the top 20 diseases related to Arthus Reaction:



Diseases related to arthus reaction

Symptoms for Arthus Reaction

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UMLS symptoms related to Arthus Reaction:


welts, other urticaria

Drugs & Therapeutics for Arthus Reaction

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Arthus Reaction


Cochrane evidence based reviews: arthus reaction

Genetic Tests for Arthus Reaction

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Anatomical Context for Arthus Reaction

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MalaCards organs/tissues related to Arthus Reaction:

34
Skin, Neutrophil, Testes, Skeletal muscle, Lung, Tongue, Eye

Animal Models for Arthus Reaction or affiliated genes

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MGI Mouse Phenotypes related to Arthus Reaction:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.3ALB, HMOX1, NOS2, SELL, TNF
2MP:00053698.0ALB, HMOX1, ICAM1, NOS2, TNF
3MP:00020067.7ALB, ICAM1, MIF, NOS2, SELL, TNF
4MP:00053857.5ALOX5, HMOX1, ICAM1, NOS2, SELL, TNF
5MP:00053877.4ALOX5, HMOX1, ICAM1, MIF, NOS2, SELL
6MP:00053977.2ALOX5, HMOX1, ICAM1, MIF, NOS2, SELL
7MP:00053797.1ALB, HMOX1, ICAM1, NOS2, SELL, TNF
8MP:00053846.8ALB, ALOX5, HMOX1, ICAM1, MIF, NOS2
9MP:00053766.5ALB, ALOX5, HMOX1, ICAM1, MIF, NOS2

Publications for Arthus Reaction

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Articles related to Arthus Reaction:

(show top 50)    (show all 157)
idTitleAuthorsYear
1
Effects of cholinotropic and cytostatic drugs on the development of Arthus reaction. (19513373)
2008
2
Involvement of gaseous low molecular monoxides in the cutaneous reverse passive Arthus reaction: cytoprotective action of carbon monoxide. (18505425)
2008
3
A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction. (10623857)
2000
4
On the role of complement and Fc gamma-receptors in the Arthus reaction. (10698344)
1999
5
Histochemical investigations of the skeletal muscle fibres during the reversed passive Arthus reaction in guinea pigs. (9151106)
1997
6
ICAM-1 mediates leukocyte-endothelium adhesive interactions in the reversed passive Arthus reaction. (8604010)
1996
7
The role of ICAM-1 in the reverse passive Arthus reaction induced pleurisy in the rat. (8548405)
1995
8
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. (8242264)
1993
9
Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction. (8228810)
1993
10
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction. (1330163)
1992
11
Suppression of vascular injury at the Arthus reaction site by a complement inhibitor, 5,5',5''-(1,3,6-naphthalene-triyl-tris[sulfonylimino])-tris (1,3-benzene disulfonic acid) hexasodium salt. (1828755)
1991
12
Serotonin metabolism in the arthus reaction. (2136904)
1990
13
Skin necrosis after injection of aminosides. Arthus reaction, local toxicity, thrombotic process or pathergy? (2141580)
1990
14
Inhibition of cellular infiltration at the site of Arthus reaction by chlorpromazine. Use of a new area integration technique. (2148738)
1990
15
The Arthus reaction in cats deficient in Hageman factor (factor XII). (2138171)
1990
16
Enhancement of the Arthus reaction and suppression of delayed type hypersensitivity (DTH) by pluronic F-68, a detergent frequently used to prepare perfluorocarbon emulsions. (2525535)
1989
17
The Arthus reaction in domestic cats. (2969157)
1988
18
Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. (2968048)
1988
19
Biogenic amines in the Arthus reaction. (2958359)
1987
20
Histamine metabolism in the Arthus reaction. (2936618)
1986
21
A specific antagonist of platelet-activating factor suppresses oedema formation in an Arthus reaction but not oedema induced by leukocyte chemoattractants in rabbit skin. (2940300)
1986
22
Impaired histamine metabolism in the Arthus reaction induced in guinea-pig skin. (3159351)
1985
23
Effects of PGF2 alpha on the active Arthus reaction in rat and rabbit tongues. (3161844)
1985
24
Ex vivo effects of nonsteroidal antiinflammatory drugs on arachidonic acid metabolism in neutrophils from a reverse passive Arthus reaction. (3156814)
1985
25
Studies on the role of polymorphonuclear leukocyte granule elastase in Arthus reaction. (6240230)
1984
26
Immune complexes and inflammation. A study of the activity of anti-inflammatory drugs in the reverse passive arthus reaction in the rat. (6221727)
1983
27
Pathways to inflammation induced by immune complexes: development of the Arthus reaction. (6211371)
1982
28
Transient immune deposits in the papillary dermis and in the epidermis. A light-microscopical study on the experimental Arthus reaction. (6449910)
1980
29
Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP. (6452106)
1980
30
Protease inhibitors reduce the reverse passive Arthus reaction. (152568)
1978
31
Distribution of immune deposits in the skin of reversed passive arthus reaction using horseradish peroxidase as antigen. (45717)
1976
32
The effect of shock on the inflammatory response. A reevaluation of the role of platelets in the active arthus reaction. (122800)
1975
33
Mechanism of action of colchicine. I. Effect of colchicine and its analogs on the reversed passive Arthus reaction and the carrageenan-induced hindpaw edema in the rat. (125325)
1975
34
The Arthus reaction in guinea-pig knee joints. A test for anti-inflammatory drugs. (1220555)
1975
35
Delayed hypersensitivity and Arthus reaction to purified hepatitis B surface antigen (HBsAg) in immunized chimpanzees. (128431)
1975
36
Light and immunofluorescent study of the Arthus reaction in the rabbit lung. (128566)
1975
37
Gastrointestinal ulcer--arthus reaction. (4273310)
1974
38
The early changes in the Arthus reaction in the rabbit oral mucosa. (4280437)
1974
39
The papulonecrotic tuberculide. From Arthus reaction to lupus vulgaris. (4279670)
1974
40
Non-hemorrhagic arthus reaction and its independence from circulating antibodies and complement. (4146960)
1973
41
Thyroid eosinophilia and cutaneous Arthus reaction simultaneously induced in the guinea-pig by antiserum to thyroglobulin. (4249611)
1970
42
Effects of neutrophils on tissues. Experiments on the Arthus reaction, the flare phenomenon, and post-phagocytic release of lysosomal enzymes. (4243806)
1969
43
Leukoegresin: a factor from rabbit skin associated with leucocytic emigration in the Arthus reaction. (4234575)
1968
44
The Arthus reaction to Candida albicans in asthma patients. (4237283)
1968
45
Inhibitory effect of large doses of histamine on the passive Arthus reaction. (4225450)
1967
46
The role of PMN-leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. I. The vascular changes and the role of PMN-leukocytes in the reversed passive Arthus reaction. (4225017)
1966
47
Prevention by intravenous injection of antigen and antibody of passive Arthus reaction to unrelated immune system. (13675297)
1959
48
Arthus reaction in the mouse and the rat after intralabial injection of antigens. (13295601)
1956
49
Quantitative study of Arthus reaction and of cutaneous anaphylaxis induced passively in the rat. (13037728)
1952
50
Effect of salicylate and tripelennamine hydrochloride (pyribenzamine) on the Arthus reaction and on bacterial allergic reactions. (18900017)
1947

Variations for Arthus Reaction

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Expression for genes affiliated with Arthus Reaction

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Search GEO for disease gene expression data for Arthus Reaction.

Pathways for genes affiliated with Arthus Reaction

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GO Terms for genes affiliated with Arthus Reaction

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Cellular components related to Arthus Reaction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.7ICAM1, SELL, TNF
2cell surfaceGO:00099868.1CR1, ICAM1, MIF, SELL, TNF
3extracellular spaceGO:00056157.7ALB, ALOX5, HMOX1, ICAM1, MIF, TNF

Biological processes related to Arthus Reaction according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemokine (C-X-C motif) ligand 2 productionGO:200034310.2MIF, TNF
2positive regulation of chemokine biosynthetic processGO:004508010.1HMOX1, TNF
3positive regulation of cytokine secretionGO:005071510.1MIF, TNF
4positive regulation of vasoconstrictionGO:004590710.1ALOX5, ICAM1
5positive regulation of nitric oxide biosynthetic processGO:00454299.9ICAM1, TNF
6negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.8HMOX1, ICAM1
7cell agingGO:00075699.7ICAM1, MIF
8positive regulation of vasodilationGO:00459099.5HMOX1, NOS2
9cellular response to lipopolysaccharideGO:00712229.3ICAM1, NOS2, TNF
10positive regulation of ERK1 and ERK2 cascadeGO:00703749.2ICAM1, MIF, TNF
11negative regulation of gene expressionGO:00106299.0MIF, NOS2, TNF
12regulation of cell proliferationGO:00421279.0MIF, NOS2, TNF
13leukocyte migrationGO:00509008.8ICAM1, MIF, SELL, TNF
14response to hypoxiaGO:00016668.3HMOX1, ICAM1, NOS2

Sources for Arthus Reaction

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet