MCID: ASB001
MIFTS: 42

Asbestosis malady

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Asbestosis

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Aliases & Descriptions for Asbestosis:

Name: Asbestosis 10 45 47 12 36 65
Idiopathic Interstitial Pneumonitis - from Asbestos Exposure 45
 
Pulmonary Fibrosis - from Asbestos Exposure 45

Classifications:



External Ids:

Disease Ontology10 DOID:10320
ICD1027 J61
ICD9CM29 501
MeSH36 D001195
NCIt42 C84573
UMLS65 C0003949

Summaries for Asbestosis

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Wikipedia:68 Asbestosis is a chronic inflammatory and scarring disease affecting the tissue of the lungs. People with... more...

MalaCards based summary: Asbestosis, also known as idiopathic interstitial pneumonitis - from asbestos exposure, is related to melanoma and asbestos intoxication. An important gene associated with Asbestosis is GSTM1 (Glutathione S-Transferase Mu 1), and among its related pathways are Naphthalene metabolism and Platinum Pathway, Pharmacokinetics/Pharmacodynamics. Affiliated tissues include lung, breast and t cells.

Disease Ontology:10 A pneumoconiosis caused by inhalation and retention of asbestos fibers.

Related Diseases for Asbestosis

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Diseases related to Asbestosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 368)
idRelated DiseaseScoreTop Affiliating Genes
1melanoma29.9MUC1, SERPINA1
2asbestos intoxication11.5
3interstitial lung disease10.4
4filamentary keratitis10.4GSTM1, GSTT1
5ocular motility disease10.4SOD2, SOD3
6ectodermal dysplasia10.4GSTM1, GSTT1
7mast syndrome10.3SOD2, SOD3
8levator syndrome10.3GSTM1, GSTT1
9noma10.3GSTM1, GSTT1
10mutiple parosteal osteochondromatous proliferations10.3GSTM1, GSTT1
11scleromalacia perforans10.3GSTM1, GSTT1
12hepatitis10.3
13giant hemangioma10.3GSTM1, GSTT1
14breast cancer10.3
15diffuse idiopathic pulmonary neuroendocrine cell hyperplasia10.2GSTM1, GSTT1
16night blindness, congenital stationary , 1d, autosomal recessive10.2GSTM1, GSTT1
17prostatitis10.2
18thyroiditis10.2
19heart aneurysm10.2CAT, SOD3
20glottis neoplasm10.2GSTM1, GSTT1, OGG1
21placental insufficiency10.2GSTM1, GSTT1, OGG1
22alopecia10.1GSTM1, SOD2
23prostate cancer10.1
24renal cell carcinoma10.1
25leukemia10.1
26lymphoma10.1
27sarcoma10.1
28gingivitis10.1
29ischemia10.1
30hypoxia10.1
31lymphoplasmacyte-rich meningioma10.1MUC1, SERPINA1
32familial short qt syndrome10.1GSTM1, MUC1, SOD2
33tetrasomy 2110.1CAT, SOD2
34myocardial infarction10.0
35arthritis10.0
36cervicitis10.0
37tuberculosis10.0
38myopathy10.0
39periodontitis10.0
40peritonitis10.0
41vasculitis10.0
42muscular dystrophy10.0
43ataxia10.0
44endotheliitis10.0
45recurrent hypersomnia10.0CAT, GSTM1, SOD2
46mucinous cystadenocarcinoma10.0CAT, GSTM1, GSTT1
47autonomic peripheral neuropathy10.0CAT, GSTM1, GSTT1
48schizophrenia9.9
49rheumatoid arthritis9.9
50lung cancer9.9

Graphical network of the top 20 diseases related to Asbestosis:



Diseases related to asbestosis

Symptoms for Asbestosis

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Drugs & Therapeutics for Asbestosis

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Drugs for Asbestosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1ArtichokeNutraceuticalPhase 28
2Respiratory System Agents3931
3XenonPhase 059

Interventional clinical trials:

idNameStatusNCT IDPhase
1Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed PopulationCompletedNCT02076672Phase 2
2Specialized Center of Research in Occupational and Immunologic Lung DiseaseCompletedNCT00005280
3Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early DiagnosisRecruitingNCT02280343
4Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung DisordersNot yet recruitingNCT02748798Phase 0

Search NIH Clinical Center for Asbestosis


Cochrane evidence based reviews: asbestosis

Genetic Tests for Asbestosis

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Anatomical Context for Asbestosis

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MalaCards organs/tissues related to Asbestosis:

33
Lung, Breast, T cells, Endothelial, Heart, Bone, Liver

Animal Models for Asbestosis or affiliated genes

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MGI Mouse Phenotypes related to Asbestosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Asbestosis

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Articles related to Asbestosis:

(show top 50)    (show all 511)
idTitleAuthorsYear
1
Acute inferior myocardial infarction with right ventricular infarction is more prone to develop cardiogenic shock. (25725666)
2015
2
Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor. (25283845)
2015
3
Conformation of BCL-XL upon Membrane Integration. (25731750)
2015
4
A randomized controlled trial of the effects of a brief intervention to increase chlamydia and gonorrhea testing uptake among young adult female emergency department patients. (25491714)
2014
5
Cerebral arteriovenous malformation associated with moyamoya disease. (25371789)
2014
6
Replication stress links structural and numerical cancer chromosomal instability. (23446422)
2013
7
Fuchs' endothelial corneal dystrophy: subjective grading versus objective grading based on the central-to-peripheral thickness ratio. (23369486)
2013
8
In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis. (23786321)
2013
9
Two-stage association study in Chinese Han identifies two independent associations in CCR1/CCR3 locus as candidate for BehAset's disease susceptibility. (22829007)
2012
10
SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC. (22015605)
2012
11
A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging. (22863908)
2012
12
Complex Decongestive Physiotherapy Treats Skin Changes like Hyperkeratosis Caused by Lymphedema. (23259083)
2012
13
Pancreatic metastases from uterine leiomyosarcoma with vascular involvement. (21396328)
2011
14
Constitutive and induced functions of the p53 gene. (21418001)
2010
15
Clinical features of rapidly progressive Alzheimer's disease. (20453509)
2010
16
CTCF controls expression and chromatin architecture of the human major histocompatibility complex class II locus. (20584980)
2010
17
Measurement of adiponectin production from differentiated metabolic stem cells. (20221981)
2010
18
Hereditary hemochromatosis: a literature review and case report. (21629607)
2010
19
Neural tube defects and herbal medicines containing lead: a possible relationship. (19028023)
2009
20
The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy. (18947877)
2009
21
C-reactive protein and colorectal adenomas: Self Defense Forces Health Study. (19469014)
2009
22
Circulating leptin levels and bone mineral density in children with biliary atresia. (18177445)
2008
23
Tumor lysis associated with sudden onset of syndrome of inappropriate antidiuretic hormone secretion. (17311695)
2007
24
Sclerosing epithelioid fibrosarcoma of the pituitary. (18097772)
2007
25
Circulating CD4+CD25+ T cells in rheumatic mitral stenosis. (17944116)
2007
26
Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors. (16385588)
2006
27
Effect of different hemodialysis regimens on genomic damage in end-stage renal failure. (16412822)
2006
28
Engineered recombinant ovomucoid third domain can desensitize Balb/c mice of egg allergy. (16792581)
2006
29
The clinical significance of ZAP-70 and CD38 expression in B-cell chronic lymphocytic leukaemia. (16524977)
2006
30
Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E. (16113099)
2005
31
Metabolic and neuropsychological phenotype in women heterozygous for ornithine transcarbamylase deficiency. (14705115)
2004
32
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. (12706853)
2003
33
NFkappaB and AP-1 DNA binding activity in patients with multiple sclerosis. (12576234)
2003
34
Low biochemical nutritional parameters in acutely ill hospitalized elderly patients with and without stage III to IV pressure ulcers. (12602578)
2002
35
Kinetics of inhibition of leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid. (12162745)
2002
36
Gene expression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects. (12397383)
2002
37
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). (11585908)
2001
38
Molecular and functional properties of the human alpha1G subunit that forms T-type calcium channels. (10692398)
2000
39
Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1. (10939284)
2000
40
Estrogens and glucocorticoids induce the expression of c-erbB2/NEU receptor in Ishikawa human endometrial cells. (9307054)
1997
41
Immunocytochemical localization of aromatic L-amino acid decarboxylase and catechol-O-methyltransferase in blood vessel wall of the human dental pulp. (8911671)
1996
42
Hucolin, a new corticosteroid-binding protein from human plasma with structural similarities to ficolins, transforming growth factor-beta 1-binding proteins. (7498469)
1995
43
The relevance of intact enkephalin molecule in predominantly delta opioid receptor mediated superoxide anion release. (8837964)
1995
44
In vitro activity of biapenem against beta-lactamase producing Enterobacteriaceae. (7889951)
1994
45
Pompe's disease--acid alpha-glucosidase deficiency--a review]. (8411709)
1993
46
Medical treatment of uterine myoma with long-acting gonadotropin-releasing hormone agonist prior to myomectomy. (8106041)
1993
47
Tetranucleotide repeat polymorphism at the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2). (1561114)
1992
48
Induction of proliferation of growth-inhibited keratinocytes and fibroblasts in monolayer culture by sodium lauryl sulfate: comparison with all-trans retinoic acid. (1919055)
1991
49
Reflex epilepsy evoked by specific psychic activity. A case report. (6496034)
1984
50
SCARLET FEVER: Preliminary Note of its Specific MicroAPrganism. (20310174)
1911

Variations for Asbestosis

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Expression for genes affiliated with Asbestosis

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Search GEO for disease gene expression data for Asbestosis.

Pathways for genes affiliated with Asbestosis

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GO Terms for genes affiliated with Asbestosis

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Cellular components related to Asbestosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00057969.6MUC1, SOD3

Biological processes related to Asbestosis according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1response to L-ascorbic acidGO:00335919.9CAT, SOD2
2response to radiationGO:00093149.9CAT, SOD2
3response to cadmium ionGO:00466869.9CAT, SOD2
4cellular oxidant detoxificationGO:00988699.7CAT, GSTT1
5response to coldGO:00094099.7IL6, SOD2
6response to nutrient levelsGO:00316679.6IL6, SOD2
7acute-phase responseGO:00069539.6IL6, SERPINA1
8superoxide metabolic processGO:00068019.6SOD2, SOD3
9glutathione metabolic processGO:00067499.6GSTM1, GSTT1, SOD2
10response to electrical stimulusGO:00516029.4IL6, SOD2
11agingGO:00075688.8CAT, IL6, SOD2
12response to oxidative stressGO:00069798.7CAT, OGG1, SOD2, SOD3
13response to drugGO:00424938.6CAT, IL6, SOD2

Sources for Asbestosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet