MCID: ASP003
MIFTS: 50

Aseptic Meningitis

Categories: Neuronal diseases

Aliases & Classifications for Aseptic Meningitis

MalaCards integrated aliases for Aseptic Meningitis:

Name: Aseptic Meningitis 12 3 14 69
Acute Aseptic Meningitis 12
Meningitis, Aseptic 42
Meningitis Aseptic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:12157
ICD10 33 G03.0
MeSH 42 D008582
NCIt 47 C118299
UMLS 69 C0025290

Summaries for Aseptic Meningitis

CDC : 3 Español: Meningitis viral

MalaCards based summary : Aseptic Meningitis, also known as acute aseptic meningitis, is related to intracranial hypertension and sinusitis. An important gene associated with Aseptic Meningitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Busulfan and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include brain, b cells and testes, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and hematopoietic system

Wikipedia : 72 Aseptic meningitis, or sterile meningitis, is a condition in which the layers lining the brain, the... more...

Related Diseases for Aseptic Meningitis

Diseases related to Aseptic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 408)
id Related Disease Score Top Affiliating Genes
1 intracranial hypertension 29.9 CXCL8 IFNG IL10
2 sinusitis 29.1 CXCL8 IL1B IL1RN NLRP3 TNF
3 rheumatoid arthritis 28.3 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
4 syphilitic aseptic meningitis 12.2
5 lymphocytic choriomeningitis 11.3
6 nonparalytic poliomyelitis 11.3
7 meningitis 11.0
8 mollaret meningitis 11.0
9 syphilitic meningitis 11.0
10 oculomotor nerve paralysis 10.8 CXCL8 IL1B
11 common peroneal nerve lesion 10.8 CXCL8 IL1B
12 tabatznik syndrome 10.8 IL1B TNF
13 spirillary rat-bite fever 10.8 CXCL8 TNF
14 lacrimal apparatus disease 10.7 CXCL8 IL1B
15 pulmonary hypertension 10.7 IL1B TNF
16 cataract 10.7 IL1B TNF
17 chancroid 10.7 CXCL8 IL1B
18 autoimmune polyglandular syndrome type 3 10.7 IFNG TNF
19 scrotal carcinoma 10.7 IL1B TNF
20 gastric cancer risk after h. pylori infection 10.7 IL1B IL1RN
21 mosaic trisomy 1 10.7 IFNG TNF
22 primary systemic mycosis 10.7 IFNG TNF
23 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.7 IL1B TNF
24 pure autonomic failure 10.7 IL10 TNF
25 lymph node palisaded myofibroblastoma 10.7 CXCL8 IL10
26 drug rash with eosinophilia and systemic symptoms 10.7 CXCL8 IL10
27 ethmoid sinus cancer 10.7 IFNG IL1B
28 acute ackee fruit intoxication 10.7 IL10 TNF
29 upper gum cancer 10.6 IL1B TNF
30 bladder calculus 10.6 IL1RN TNF
31 hidradenitis suppurativa 10.6 CXCL8 IL10
32 moved to 244450 10.6 IL1B TNF
33 nonspecific interstitial pneumonia 10.6 CXCL8 IL10
34 multiple familial trichoepithelioma 10.6 IL10 TNF
35 lagophthalmos 10.6 IL10 TNF
36 bipolar i disorder 10.6 IL1B TNF
37 type 1 papillary adenoma of the kidney 10.6 IL10 TNF
38 eye accommodation disease 10.6 IFNG IL10
39 lung sarcoma 10.6 IL1B TNF
40 endosalpingiosis 10.6 IL10 TNF
41 urofacial syndrome 1 10.6 CXCL8 IL10
42 subglottis neoplasm 10.6 CXCL8 IL1B
43 tinea favosa 10.6 IL1B TNF
44 graft-versus-host disease, protection against 10.6 IFNG IL10
45 central nervous system leiomyosarcoma 10.6 IL1B TNF
46 thelaziasis 10.6 IFNG IL10
47 idiopathic dilatation of the pulmonary artery 10.6 IL10 TNF
48 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.6 IL1B TNF
49 dumping syndrome 10.6 IFNG IL10
50 ethmoid sinus adenocarcinoma 10.6 IL10 TNF

Graphical network of the top 20 diseases related to Aseptic Meningitis:



Diseases related to Aseptic Meningitis

Symptoms & Phenotypes for Aseptic Meningitis

GenomeRNAi Phenotypes related to Aseptic Meningitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.32 CXCL8 IL10 IL1B NLRP3 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.32 IL10 IL1B NLRP3 TNF CXCL8

MGI Mouse Phenotypes related to Aseptic Meningitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 IL1RN LTF NLRP3 SOD2 TNF CFI
2 homeostasis/metabolism MP:0005376 10.07 IL10 IL1B IL1R1 IL1RN LTF NLRP3
3 cellular MP:0005384 10.03 IFNG IL10 IL1R1 IL1RN LTF NLRP3
4 cardiovascular system MP:0005385 10 IL10 IL1B IL1R1 IL1RN SOD2 TNF
5 immune system MP:0005387 9.97 IFNG IL10 IL1B IL1R1 IL1RN LTF
6 integument MP:0010771 9.86 IFNG IL10 IL1B IL1R1 IL1RN NLRP3
7 liver/biliary system MP:0005370 9.7 IFNG IL10 IL1R1 LTF NLRP3 SOD2
8 neoplasm MP:0002006 9.5 IFNG IL10 IL1B IL1R1 LTF SOD2
9 skeleton MP:0005390 9.17 IFNG IL10 IL1B IL1R1 IL1RN NLRP3

Drugs & Therapeutics for Aseptic Meningitis

Drugs for Aseptic Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 61)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Busulfan Approved, Investigational Phase 2 55-98-1 2478
2
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
3
Carmustine Approved Phase 2 154-93-8 2578
4
Clonazepam Approved, Illicit Phase 2 1622-61-3 2802
5
Cytarabine Approved, Investigational Phase 2 147-94-4 6253
6
Etoposide Approved Phase 2 33419-42-0 36462
7
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754 657311
8
Ifosfamide Approved Phase 2 3778-73-2 3690
9
Mechlorethamine Approved Phase 2 51-75-2 4033
10
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
11
rituximab Approved Phase 2 174722-31-7 10201696
12 Thiotepa Approved Phase 2 52-24-4 5453
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
14
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
15 Alkylating Agents Phase 2
16 Anti-Infective Agents Phase 2
17 Antimetabolites Phase 2
18 Antimetabolites, Antineoplastic Phase 2
19 Antineoplastic Agents, Phytogenic Phase 2
20 Antirheumatic Agents Phase 2
21 Antiviral Agents Phase 2
22 Cortisol succinate Phase 2
23 Dermatologic Agents Phase 2
24 Etoposide phosphate Phase 2
25 Folic Acid Antagonists Phase 2
26 Hydrocortisone 17-butyrate 21-propionate Phase 2
27 Hydrocortisone acetate Phase 2
28 Immunosuppressive Agents Phase 2
29 Isophosphamide mustard Phase 2
30 Nucleic Acid Synthesis Inhibitors Phase 2
31 Topoisomerase Inhibitors Phase 2
32 Vitamin B Complex Phase 2
33 Folate Nutraceutical Phase 2
34 Vitamin B9 Nutraceutical Phase 2
35 Anti-Bacterial Agents Phase 1
36 Antibiotics, Antitubercular Phase 1
37 Pharmaceutical Solutions Phase 1
38
Lamotrigine Approved, Investigational 84057-84-1 3878
39
Ceftriaxone Approved 73384-59-5 5479530 5361919
40
Dopamine Approved 51-61-6, 62-31-7 681
41
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
42 Anticonvulsants
43 calcium channel blockers
44 Calcium, Dietary
45 Diuretics, Potassium Sparing
46 Excitatory Amino Acid Antagonists
47 Excitatory Amino Acids
48 Neurotransmitter Agents
49 Sodium Channel Blockers
50 Acyclovir

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement Recruiting NCT02329080 Phase 2 Methotrexate;Rituximab;Cytarabine;Thiotepa;liposomial cytarabine;Etoposide;Ifosfamide;Carmustine
2 A Study of Doripenem in CerebrospinalFluid After Doripenem Administration in Pediatric Patients Less Than 1 Year of Age Terminated NCT01366651 Phase 1 Doripenem;Doripenem
3 WEUSKOP6166: Lamotrigine and Aseptic Meningitis Completed NCT01657864 Lamotrigine
4 Aseptic Meningoencephalitis in Slovenia Recruiting NCT02328469 symptomatic therapy;Ceftriaxone or Doxycycline;Acyclovir
5 Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia Recruiting NCT02669836
6 A New Enzymatic Assay for Rapid Diagnosing of Central Nervous System Enteroviral Infection Withdrawn NCT00864903

Search NIH Clinical Center for Aseptic Meningitis

Cochrane evidence based reviews: meningitis, aseptic

Genetic Tests for Aseptic Meningitis

Anatomical Context for Aseptic Meningitis

MalaCards organs/tissues related to Aseptic Meningitis:

39
Brain, B Cells, Testes, T Cells, Pituitary, Neutrophil, Heart

Publications for Aseptic Meningitis

Articles related to Aseptic Meningitis:

(show top 50) (show all 607)
id Title Authors Year
1
Association of anti-triosephosphate isomerase antibodies with aseptic meningitis in patients with neuropsychiatric systemic lupus erythematosus. ( 28451873 )
2017
2
Enhancing global vaccine pharmacovigilance: Proof-of-concept study on aseptic meningitis and immune thrombocytopenic purpura following measles-mumps containing vaccination. ( 28558983 )
2017
3
Clinical, epidemiological and etiological studies of adult aseptic meningitis: Report of 11 cases with varicella zoster virus meningitis. ( 28804114 )
2017
4
Aseptic meningitis following a bupivacaine spinal anesthesia. ( 28904717 )
2017
5
Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis. ( 28639536 )
2017
6
Aseptic meningitis in relapsing polychondritis: a case report and literature review. ( 28361234 )
2017
7
IVIG Associated Aseptic Meningitis in a Renal Transplant Patient. ( 28620559 )
2017
8
Cerebrospinal Fluid Cytokines Correlate With Aseptic Meningitis and Blood-Brain Barrier Function in Neonatal-Onset Multisystem Inflammatory Disease: Central Nervous System Biomarkers in Neonatal-Onset Multisystem Inflammatory Disease Correlate With Central Nervous System Inflammation. ( 28118536 )
2017
9
Infliximab-Induced Aseptic Meningitis during the Treatment of Psoriatic Arthritis. ( 28611632 )
2017
10
Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. ( 28761901 )
2017
11
Recurrent trimethoprim-sulfamethoxazole-induced aseptic meningitis with associated ampicillin-induced myoclonic twitchesa8c. ( 28291512 )
2017
12
Human enteroviruses in cerebrospinal fluid of children with suspected aseptic meningitis: A study in northern Iran. ( 28702151 )
2017
13
Pathogenesis of coxsackievirus B2 in mice: characterisation of clinical isolates of the coxsackievirus B2 from patients with myocarditis and aseptic meningitis in Korea. ( 28384999 )
2017
14
Herpes zoster-related aseptic meningitis and encephalomeningitis: A single faculty retrospective case study. ( 28557114 )
2017
15
Aseptic meningitis in adults and children: Diagnostic and management challenges. ( 28806629 )
2017
16
Molecular detection and genotyping of enteroviruses from CSF samples of patients with suspected sepsis-like illness and/or aseptic meningitis from 2012 to 2015 in West Bank, Palestine. ( 28225788 )
2017
17
A Teenage Girl With Aseptic Meningitis and Unilateral Blurry Vision. ( 28687842 )
2017
18
Risk Factors for Aseptic Meningitis in Herpes Zoster Patients. ( 28566903 )
2017
19
First Case Report of Aseptic Meningitis Induced by Adalimumab Administered for Treatment of Chronic Plaque Psoriasis. ( 28570223 )
2017
20
Clinical commentary on 'Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis', by Foley et al. ( 28639492 )
2017
21
Enterovirus-D68 in the Cerebrospinal Fluid of Two Children with Aseptic Meningitis. ( 26859634 )
2016
22
Aseptic Meningitis with Craniopharyngioma Resection: Consideration after Endoscopic Surgery. ( 27722072 )
2016
23
Neurosarcoidosis Presenting as Aseptic Meningitis in an Immunosuppressed Renal Transplant Recipient. ( 26863472 )
2016
24
A Rare Complication of Trimethoprim-Sulfamethoxazole: Drug Induced Aseptic Meningitis. ( 27579194 )
2016
25
Complete Genome Sequence Analysis of Echovirus 18 Associated with Aseptic Meningitis in Hebei Province, China, in 2015. ( 27789638 )
2016
26
Neuropsychiatric symptoms among adult patients with aseptic meningitis: a prospective case series. ( 26685715 )
2016
27
Usefulness of inflammatory biomarkers in discriminating between bacterial and aseptic meningitis in hospitalized children from a population with low vaccination coverage. ( 27186188 )
2016
28
Aseptic meningitis and anti-I^2-glycoprotein 1 antibodies in Sweet syndrome. ( 27452622 )
2016
29
Amoxicillin-induced aseptic meningitis: case report and review of published casesa8c. ( 27443662 )
2016
30
Etiologies and Management of Aseptic Meningitis in Patients Admitted to an Internal Medicine Department. ( 26765411 )
2016
31
Complete genome sequence of a coxsackievirus B3 recombinant isolated from an aseptic meningitis outbreak in eastern China. ( 27236460 )
2016
32
Laboratory diagnosis and genetic analysis of a family clustering outbreak of aseptic meningitis due to echovirus 30. ( 27646838 )
2016
33
Aseptic meningitis following therapy with immune globulins: a combination of product features and patient characteristics? ( 27807853 )
2016
34
Ehrlichiosis Induced Aseptic Meningitis and Second Degree Heart Block in an Adolescent Male. ( 27097347 )
2016
35
Etiology of aseptic meningitis and clinical characteristics in immune-competent adults. ( 26118835 )
2016
36
Familial Mediterranean Fever Presenting with Recurrent Aseptic Meningitis: A Case Report. ( 27622671 )
2016
37
Associations between Meteorological Factors and Aseptic Meningitis in Six Metropolitan Provinces of the Republic of Korea. ( 27916923 )
2016
38
Aseptic Meningitis Caused by Lassa Virus: Case Series Report. ( 27957363 )
2016
39
Blood-CSF-barrier dysfunction is a marker for encephalitic involvement in patients with aseptic meningitis/meningoencephalitis. ( 27736668 )
2016
40
Cat-scratch disease presenting as parotid gland abscess and aseptic meningitis. ( 27426218 )
2016
41
Molecular identification of human enteroviruses associated with aseptic meningitis in Yunnan province, Southwest China. ( 27652088 )
2016
42
Cetuximab-induced aseptic meningitis: case report and review of a rare adverse event. ( 27378078 )
2016
43
Aseptic meningitis after measles-mumps-rubella (MMR) vaccination. ( 27181175 )
2016
44
Atypical leptospirosis: an overlooked cause of aseptic meningitis. ( 26964740 )
2016
45
A case of aseptic meningitis without neck rigidity occurring in a metastatic melanoma patient treated with ipilimumab. ( 28007669 )
2016
46
Herpes simplex virus type 2-associated recurrent aseptic meningitis (Mollaret's meningitis) with a recurrence after 11-year interval: a case report. ( 27773908 )
2016
47
Rapid detection of enterovirus in cerebrospinal fluid by a fully-automated PCR assay is associated with improved management of aseptic meningitis in adult patients. ( 25542472 )
2015
48
Incidence and natural history of intravenous immunoglobulin-induced aseptic meningitis: a retrospective review at a single tertiary care center. ( 26095012 )
2015
49
Elucidation of Echovirus 30's Origin and Transmission during the 2012 Aseptic Meningitis Outbreak in Guangdong, China, through Continuing Environmental Surveillance. ( 25616804 )
2015
50
Varicella Zoster Aseptic Meningitis: Report of an Atypical Case and Literature Review. ( 26342350 )
2015

Variations for Aseptic Meningitis

Expression for Aseptic Meningitis

Search GEO for disease gene expression data for Aseptic Meningitis.

Pathways for Aseptic Meningitis

Pathways related to Aseptic Meningitis according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.88 CFI CXCL8 IFNG IL10 IL1B IL1R1
2
Show member pathways
13.58 CXCL8 IFNG IL10 IL1B IL1R1 SOD2
3
Show member pathways
13.44 CXCL8 IFNG IL10 IL1B IL1R1 TNF
4
Show member pathways
13.28 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
5
Show member pathways
12.92 CXCL8 IL1B IL1R1 IL1RN NLRP3 TNF
6
Show member pathways
12.83 CXCL8 IFNG IL10 IL1B TNF
7
Show member pathways
12.82 CXCL8 IFNG IL10 IL1B TNF
8
Show member pathways
12.77 CXCL8 IFNG IL1B NLRP3 TNF
9
Show member pathways
12.66 CXCL8 IFNG IL1B TNF
10
Show member pathways
12.61 IFNG IL1B IL1R1 TNF
11
Show member pathways
12.55 IFNG IL10 IL1B IL1R1 TNF
12
Show member pathways
12.54 IFNG IL10 IL1B TNF
13 12.49 IFNG IL10 IL1B IL1RN TNF
14
Show member pathways
12.4 IFNG IL10 IL1B TNF
15
Show member pathways
12.32 CXCL8 IFNG IL1B TNF
16
Show member pathways
12.24 IFNG IL10 IL1B TNF
17
Show member pathways
12.22 CXCL8 IFNG IL1B IL1R1 TNF
18 12.2 IFNG IL10 IL1B TNF
19
Show member pathways
12.13 CXCL8 IFNG IL1B IL1R1 TNF
20 12.1 CXCL8 IL10 IL1B IL1RN TNF
21
Show member pathways
12.08 CXCL8 IFNG IL10 IL1B TNF
22 12.07 IFNG IL1B IL1R1 TNF
23 12.02 IFNG IL1B IL1R1 TNF
24 11.96 IFNG IL10 TNF
25 11.95 CXCL8 IL10 IL1B TNF
26
Show member pathways
11.94 IFNG IL1B IL1R1
27 11.91 CXCL8 IFNG IL1B
28
Show member pathways
11.91 IFNG IL10 IL1B TNF
29 11.91 CXCL8 IFNG IL1B IL1R1 TNF
30
Show member pathways
11.89 IFNG IL1B IL1R1
31 11.88 CXCL8 IL1B TNF
32 11.87 IL1B IL1R1 TNF
33 11.85 CXCL8 IL1B IL1R1 TNF
34 11.81 CXCL8 IFNG IL1B
35 11.81 CXCL8 IFNG IL1B TNF
36
Show member pathways
11.75 CXCL8 IFNG TNF
37 11.73 IFNG IL10 IL1B TNF
38 11.66 CXCL8 IL1B TNF
39
Show member pathways
11.64 CXCL8 IFNG IL1B TNF
40 11.62 IFNG IL10 IL1B IL1R1 TNF
41 11.6 CXCL8 IL1B TNF
42 11.54 CXCL8 IL10 IL1B NLRP3 TNF
43 11.53 IFNG IL1B TNF
44 11.53 IFNG IL1B TNF
45 11.49 IFNG IL1B TNF
46
Show member pathways
11.46 IL1B IL1R1 TNF
47
Show member pathways
11.42 IFNG IL10 TNF
48 11.42 CXCL8 IFNG IL10 IL1B IL1R1 TNF
49 11.36 IL10 IL1B TNF
50 11.31 IFNG IL1B TNF

GO Terms for Aseptic Meningitis

Cellular components related to Aseptic Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 CFI CXCL8 IFNG IL10 IL1B IL1RN
2 extracellular region GO:0005576 9.32 CFI CXCL8 IFNG IL10 IL1B IL1R1

Biological processes related to Aseptic Meningitis according to GeneCards Suite gene sharing:

(show all 46)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.92 CXCL8 IFNG IL10 IL1B SOD2
2 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.86 IL1B LTF TNF
3 defense response to bacterium GO:0042742 9.86 IFNG IL10 LTF TNF
4 positive regulation of protein phosphorylation GO:0001934 9.85 IFNG IL1B TNF
5 defense response GO:0006952 9.84 CXCL8 NLRP3 TNF
6 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.83 IL10 IL1B TNF
7 inflammatory response GO:0006954 9.8 CXCL8 IL10 IL1B IL1RN NLRP3 TNF
8 response to glucocorticoid GO:0051384 9.79 IL10 IL1RN TNF
9 regulation of insulin secretion GO:0050796 9.78 IFNG IL1B TNF
10 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.78 IL1B LTF NLRP3 TNF
11 neutrophil chemotaxis GO:0030593 9.77 CXCL8 IFNG IL1B
12 humoral immune response GO:0006959 9.74 IFNG LTF TNF
13 positive regulation of interleukin-8 production GO:0032757 9.7 IL1B TNF
14 negative regulation of interleukin-6 production GO:0032715 9.69 IL10 TNF
15 positive regulation of interleukin-1 beta secretion GO:0050718 9.69 IFNG NLRP3
16 positive regulation of protein complex assembly GO:0031334 9.69 IFNG TNF
17 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.68 IL10 TNF
18 defense response to protozoan GO:0042832 9.68 IFNG IL10
19 positive regulation of NF-kappaB import into nucleus GO:0042346 9.67 IL1B TNF
20 positive regulation of osteoclast differentiation GO:0045672 9.67 IFNG TNF
21 embryonic digestive tract development GO:0048566 9.66 CXCL8 TNF
22 negative regulation of lipid catabolic process GO:0050995 9.66 IL1B TNF
23 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.65 IL1B TNF
24 response to molecule of bacterial origin GO:0002237 9.65 CXCL8 IL10
25 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.64 IL10 IL1RN
26 regulation of defense response to virus by host GO:0050691 9.64 IFNG IL1B
27 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.63 IFNG IL1B
28 endothelial cell apoptotic process GO:0072577 9.63 IL10 TNF
29 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.63 IFNG IL1B TNF
30 positive regulation of MHC class II biosynthetic process GO:0045348 9.62 IFNG IL10
31 regulation of establishment of endothelial barrier GO:1903140 9.62 IL1B TNF
32 negative regulation of growth of symbiont in host GO:0044130 9.61 IFNG IL10 TNF
33 negative regulation of cytokine secretion involved in immune response GO:0002740 9.59 IL10 TNF
34 positive regulation of fever generation GO:0031622 9.58 IL1B TNF
35 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.58 IL10 IL1B TNF
36 positive regulation of nitric oxide biosynthetic process GO:0045429 9.56 IFNG IL1B SOD2 TNF
37 sequestering of triglyceride GO:0030730 9.55 IL1B TNF
38 cellular response to lipopolysaccharide GO:0071222 9.55 CXCL8 IFNG IL10 NLRP3 TNF
39 interleukin-1 beta production GO:0032611 9.54 IL1B NLRP3
40 positive regulation of chemokine biosynthetic process GO:0045080 9.54 IFNG IL1B TNF
41 receptor biosynthetic process GO:0032800 9.51 IL10 TNF
42 immune response GO:0006955 9.5 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
43 positive regulation of vitamin D biosynthetic process GO:0060557 9.49 IFNG TNF
44 fever generation GO:0001660 9.28 IL1B
45 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 8.8 IFNG IL1B TNF
46 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.1 IFNG IL10 IL1B NLRP3 TNF

Molecular functions related to Aseptic Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CXCL8 IFNG IL10 IL1B IL1RN TNF
2 interleukin-1 receptor binding GO:0005149 8.96 IL1B IL1RN

Sources for Aseptic Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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