MCID: ASP003
MIFTS: 54

Aseptic Meningitis

Categories: Neuronal diseases

Aliases & Classifications for Aseptic Meningitis

MalaCards integrated aliases for Aseptic Meningitis:

Name: Aseptic Meningitis 12 72 3 14 69
Acute Aseptic Meningitis 12
Meningitis, Aseptic 41
Meningitis Aseptic 51

Classifications:



External Ids:

Disease Ontology 12 DOID:12157
ICD10 32 G03.0
MeSH 41 D008582
NCIt 46 C118299
UMLS 69 C0025290

Summaries for Aseptic Meningitis

CDC : 3 Español: Meningitis viral

MalaCards based summary : Aseptic Meningitis, also known as acute aseptic meningitis, is related to meningitis and mixed connective tissue disease. An important gene associated with Aseptic Meningitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Busulfan and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include brain, b cells and t cells, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 72 Aseptic meningitis, or sterile meningitis, is a condition in which the layers lining the brain, the... more...

Related Diseases for Aseptic Meningitis

Diseases related to Aseptic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 409)
# Related Disease Score Top Affiliating Genes
1 meningitis 30.7 CXCL8 IFNG IL10 IL1B NLRP3 TNF
2 mixed connective tissue disease 30.3 IFNG IL10 TNF
3 connective tissue disease 30.3 IFNG IL10 TNF
4 poliomyelitis 30.3 IFNG IL10 TNF
5 bacterial meningitis 30.2 CXCL8 IL10 IL1B TNF
6 neuritis 30.2 IFNG IL1B TNF
7 exanthem 30.1 IL1RN NLRP3 TNF
8 scrub typhus 30.1 IL10 IL1B TNF
9 multiple sclerosis 30.1 IFNG IL10 IL1B TNF
10 leptospirosis 30.1 CXCL8 IL10 IL1B TNF
11 haemophilus influenzae 30.0 CXCL8 IL1B TNF
12 myasthenia gravis 30.0 IFNG IL10 TNF
13 mycobacterium tuberculosis 1 30.0 IFNG IL10 TNF
14 adult-onset still's disease 30.0 IL1B IL1R1 IL1RN TNF
15 typhoid fever 29.9 IFNG IL1B TNF
16 transverse myelitis 29.9 CXCL8 IL10 TNF
17 common variable immunodeficiency 29.9 IFNG IL10 TNF
18 osteoarthritis 29.9 CXCL8 IL1B TNF
19 pneumonia 29.8 CXCL8 IL10 IL1B TNF
20 psoriatic arthritis 29.8 CD58 IL1B TNF
21 mouth disease 29.8 IFNG IL10 IL1B TNF
22 familial mediterranean fever 29.6 IL1B IL1RN NLRP3 TNF
23 otitis media 29.6 CXCL8 IL10 IL1B TNF
24 lymphadenitis 29.6 CXCL8 IFNG IL10 IL1B TNF
25 crohn's disease 29.5 IFNG IL10 IL1B TNF
26 arthritis 29.4 CXCL8 IFNG IL10 IL1B IL1RN TNF
27 brucellosis 29.4 CXCL8 IFNG IL10 IL1RN TNF
28 juvenile rheumatoid arthritis 29.4 IL1B IL1R1 IL1RN TNF
29 adult respiratory distress syndrome 29.4 CXCL8 IL10 IL1R1 TNF
30 uveitis 29.3 IFNG IL10 IL1R1 TNF
31 rheumatoid arthritis 28.7 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
32 psoriasis 28.5 CD58 CXCL8 IFNG IL10 IL1B TNF
33 syphilitic aseptic meningitis 12.4
34 viral meningitis 11.4
35 lymphocytic choriomeningitis 11.4
36 nonparalytic poliomyelitis 11.4
37 epidermoid brain cyst 11.3
38 syphilitic meningitis 11.2
39 mollaret meningitis 11.1
40 recurrent corneal erosion 10.5 CXCL8 IL1B
41 bagassosis 10.5 CXCL8 IL1B
42 polyposis, gastric 10.5 IL1B TNF
43 systemic onset juvenile idiopathic arthritis 10.5 IL1B TNF
44 streptococcal toxic-shock syndrome 10.5 CXCL8 TNF
45 kashin-beck disease 10.5 IL1B TNF
46 peptic esophagitis 10.5 CXCL8 IL1B
47 opisthorchiasis 10.5 CXCL8 IL1B
48 autoimmune myocarditis 10.5 IFNG TNF
49 burns 10.5 IL1B TNF
50 laryngitis 10.4 IL1B TNF

Graphical network of the top 20 diseases related to Aseptic Meningitis:



Diseases related to Aseptic Meningitis

Symptoms & Phenotypes for Aseptic Meningitis

GenomeRNAi Phenotypes related to Aseptic Meningitis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.32 CXCL8 IL10 IL1B NLRP3 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.32 CXCL8 IL10 IL1B NLRP3 TNF

MGI Mouse Phenotypes related to Aseptic Meningitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.01 NLRP3 IL10 SOD2 IL1B TNF IL1R1
2 cardiovascular system MP:0005385 9.98 IL10 SOD2 IL1B TNF IL1R1 IFNG
3 hematopoietic system MP:0005397 9.97 NLRP3 IL10 SOD2 IL1B TNF IL1R1
4 immune system MP:0005387 9.92 NLRP3 IL10 SOD2 IL1B TNF IL1R1
5 integument MP:0010771 9.86 SOD2 IL1B TNF IL1R1 IFNG IL1RN
6 liver/biliary system MP:0005370 9.63 SOD2 TNF IL1R1 IFNG NLRP3 IL10
7 neoplasm MP:0002006 9.43 SOD2 IL1B TNF IL1R1 IFNG IL10
8 skeleton MP:0005390 9.17 NLRP3 IL10 IL1B TNF IL1R1 IFNG

Drugs & Therapeutics for Aseptic Meningitis

Drugs for Aseptic Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 60)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Busulfan Approved, Investigational Phase 2 55-98-1 2478
2
Carboplatin Approved Phase 2 41575-94-4 10339178 38904 498142
3
Carmustine Approved, Investigational Phase 2 154-93-8 2578
4
Clonazepam Approved, Illicit Phase 2 1622-61-3 2802
5
Cytarabine Approved, Investigational Phase 2 147-94-4 6253
6
Etoposide Approved Phase 2 33419-42-0 36462
7
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 657311 5754
8
Ifosfamide Approved Phase 2 3778-73-2 3690
9
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
10
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
11
rituximab Approved Phase 2 174722-31-7 10201696
12 Thiotepa Approved, Investigational Phase 2 52-24-4 5453
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
14
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
15 Alkylating Agents Phase 2
16 Anti-Infective Agents Phase 2
17 Antimetabolites Phase 2
18 Antimetabolites, Antineoplastic Phase 2
19 Antineoplastic Agents, Phytogenic Phase 2
20 Antirheumatic Agents Phase 2
21 Antiviral Agents Phase 2
22 Cortisol succinate Phase 2
23 Dermatologic Agents Phase 2
24 Etoposide phosphate Phase 2
25 Folic Acid Antagonists Phase 2
26 Hydrocortisone 17-butyrate 21-propionate Phase 2
27 Hydrocortisone acetate Phase 2
28 Immunosuppressive Agents Phase 2
29 Isophosphamide mustard Phase 2 0
30 Nucleic Acid Synthesis Inhibitors Phase 2
31 Topoisomerase Inhibitors Phase 2
32 Vitamin B Complex Phase 2
33 Folate Nutraceutical Phase 2
34 Vitamin B9 Nutraceutical Phase 2
35
Lamotrigine Approved, Investigational 84057-84-1 3878
36
Ceftriaxone Approved 73384-59-5 5479530 5361919
37
Dopamine Approved 51-61-6, 62-31-7 681
38
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
39 Anticonvulsants
40 calcium channel blockers
41 Calcium, Dietary
42 Diuretics, Potassium Sparing
43 Excitatory Amino Acid Antagonists
44 Excitatory Amino Acids
45 Neurotransmitter Agents
46 Sodium Channel Blockers
47 Acyclovir
48 Anti-Bacterial Agents
49 Antibiotics, Antitubercular
50 Antiemetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement Recruiting NCT02329080 Phase 2 Methotrexate;Rituximab;Cytarabine;Thiotepa;liposomial cytarabine;Etoposide;Ifosfamide;Carmustine
2 WEUSKOP6166: Lamotrigine and Aseptic Meningitis Completed NCT01657864 Lamotrigine
3 Aseptic Meningoencephalitis in Slovenia Recruiting NCT02328469 symptomatic therapy;Ceftriaxone or Doxycycline;Acyclovir
4 Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia Recruiting NCT02669836
5 Central Nervous System Infections in Denmark Recruiting NCT03418441
6 A New Enzymatic Assay for Rapid Diagnosing of Central Nervous System Enteroviral Infection Withdrawn NCT00864903

Search NIH Clinical Center for Aseptic Meningitis

Cochrane evidence based reviews: meningitis, aseptic

Genetic Tests for Aseptic Meningitis

Anatomical Context for Aseptic Meningitis

MalaCards organs/tissues related to Aseptic Meningitis:

38
Brain, B Cells, T Cells, Testes, Pituitary, Neutrophil, Heart

Publications for Aseptic Meningitis

Articles related to Aseptic Meningitis:

(show top 50) (show all 616)
# Title Authors Year
1
Drug-induced aseptic meningitis: A possible T-cell-mediated hypersensitivity. ( 29310902 )
2018
2
Analysis of enterovirus types in patients with symptoms of aseptic meningitis in 2014 in Shandong, China. ( 29407377 )
2018
3
Drug-induced aseptic meningitis: a mini-review. ( 29364542 )
2018
4
Clinical commentary on 'Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis', by Foley et al. ( 28639492 )
2017
5
Not All Aseptic Meningitis Is Created Equal. ( 29191826 )
2017
6
Infliximab-Induced Aseptic Meningitis during the Treatment of Psoriatic Arthritis. ( 28611632 )
2017
7
Chemokines CXCL10, CXCL11, and CXCL13 in acute disseminated encephalomyelitis, non-polio enterovirus aseptic meningitis, and neuroborreliosis: CXCL10 as initial discriminator in diagnostic algorithm? ( 29288471 )
2017
8
Aseptic meningitis in relapsing polychondritis: a case report and literature review. ( 28361234 )
2017
9
Enhancing global vaccine pharmacovigilance: Proof-of-concept study on aseptic meningitis and immune thrombocytopenic purpura following measles-mumps containing vaccination. ( 28558983 )
2017
10
Pathogenesis of coxsackievirus B2 in mice: characterisation of clinical isolates of the coxsackievirus B2 from patients with myocarditis and aseptic meningitis in Korea. ( 28384999 )
2017
11
IVIG Associated Aseptic Meningitis in a Renal Transplant Patient. ( 28620559 )
2017
12
Risk Factors for Aseptic Meningitis in Herpes Zoster Patients. ( 28566903 )
2017
13
Aseptic meningitis due to reperfusion injury after carotid artery stenting. ( 28991696 )
2017
14
First Case Report of Aseptic Meningitis Induced by Adalimumab Administered for Treatment of Chronic Plaque Psoriasis. ( 28570223 )
2017
15
A Teenage Girl With Aseptic Meningitis and Unilateral Blurry Vision. ( 28687842 )
2017
16
Human enteroviruses in cerebrospinal fluid of children with suspected aseptic meningitis: A study in northern Iran. ( 28702151 )
2017
17
Association of anti-triosephosphate isomerase antibodies with aseptic meningitis in patients with neuropsychiatric systemic lupus erythematosus. ( 28451873 )
2017
18
Molecular detection and genotyping of enteroviruses from CSF samples of patients with suspected sepsis-like illness and/or aseptic meningitis from 2012 to 2015 in West Bank, Palestine. ( 28225788 )
2017
19
Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis. ( 28639536 )
2017
20
Aseptic meningitis following a bupivacaine spinal anesthesia. ( 28904717 )
2017
21
A case of aseptic meningitis in a cetuximab-experienced patient with metastatic colon cancer. ( 29157147 )
2017
22
Cerebrospinal Fluid Cytokines Correlate With Aseptic Meningitis and Blood-Brain Barrier Function in Neonatal-Onset Multisystem Inflammatory Disease: Central Nervous System Biomarkers in Neonatal-Onset Multisystem Inflammatory Disease Correlate With Central Nervous System Inflammation. ( 28118536 )
2017
23
Serum interleukin-6 levels as an indicator of aseptic meningitis among children with enterovirus 71-induced hand, foot and mouth disease. ( 29231065 )
2017
24
Aseptic meningitis in adults and children: Diagnostic and management challenges. ( 28806629 )
2017
25
Recurrent trimethoprim-sulfamethoxazole-induced aseptic meningitis with associated ampicillin-induced myoclonic twitchesa8c. ( 28291512 )
2017
26
Herpes zoster-related aseptic meningitis and encephalomeningitis: A single faculty retrospective case study. ( 28557114 )
2017
27
Clinical, epidemiological and etiological studies of adult aseptic meningitis: Report of 11 cases with varicella zoster virus meningitis. ( 28804114 )
2017
28
USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS. ( 29185620 )
2017
29
Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. ( 28761901 )
2017
30
Aseptic meningitis and anti-I^2-glycoprotein 1 antibodies in Sweet syndrome. ( 27452622 )
2016
31
Complete Genome Sequence Analysis of Echovirus 18 Associated with Aseptic Meningitis in Hebei Province, China, in 2015. ( 27789638 )
2016
32
Neuropsychiatric symptoms among adult patients with aseptic meningitis: a prospective case series. ( 26685715 )
2016
33
Molecular identification of human enteroviruses associated with aseptic meningitis in Yunnan province, Southwest China. ( 27652088 )
2016
34
Neurosarcoidosis Presenting as Aseptic Meningitis in an Immunosuppressed Renal Transplant Recipient. ( 26863472 )
2016
35
Aseptic Meningitis with Craniopharyngioma Resection: Consideration after Endoscopic Surgery. ( 27722072 )
2016
36
Blood-CSF-barrier dysfunction is a marker for encephalitic involvement in patients with aseptic meningitis/meningoencephalitis. ( 27736668 )
2016
37
Complete genome sequence of a coxsackievirus B3 recombinant isolated from an aseptic meningitis outbreak in eastern China. ( 27236460 )
2016
38
Usefulness of inflammatory biomarkers in discriminating between bacterial and aseptic meningitis in hospitalized children from a population with low vaccination coverage. ( 27186188 )
2016
39
Etiologies and Management of Aseptic Meningitis in Patients Admitted to an Internal Medicine Department. ( 26765411 )
2016
40
Cetuximab-induced aseptic meningitis: case report and review of a rare adverse event. ( 27378078 )
2016
41
Ehrlichiosis Induced Aseptic Meningitis and Second Degree Heart Block in an Adolescent Male. ( 27097347 )
2016
42
Associations between Meteorological Factors and Aseptic Meningitis in Six Metropolitan Provinces of the Republic of Korea. ( 27916923 )
2016
43
Familial Mediterranean Fever Presenting with Recurrent Aseptic Meningitis: A Case Report. ( 27622671 )
2016
44
Atypical leptospirosis: an overlooked cause of aseptic meningitis. ( 26964740 )
2016
45
Herpes simplex virus type 2-associated recurrent aseptic meningitis (Mollaret's meningitis) with a recurrence after 11-year interval: a case report. ( 27773908 )
2016
46
A case of aseptic meningitis without neck rigidity occurring in a metastatic melanoma patient treated with ipilimumab. ( 28007669 )
2016
47
Etiology of aseptic meningitis and clinical characteristics in immune-competent adults. ( 26118835 )
2016
48
Aseptic meningitis following therapy with immune globulins: a combination of product features and patient characteristics? ( 27807853 )
2016
49
Laboratory diagnosis and genetic analysis of a family clustering outbreak of aseptic meningitis due to echovirus 30. ( 27646838 )
2016
50
Amoxicillin-induced aseptic meningitis: case report and review of published casesa8c. ( 27443662 )
2016

Variations for Aseptic Meningitis

Expression for Aseptic Meningitis

Search GEO for disease gene expression data for Aseptic Meningitis.

Pathways for Aseptic Meningitis

Pathways related to Aseptic Meningitis according to GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.94 CD58 CXCL8 IFNG IL10 IL1B IL1R1
2
Show member pathways
13.58 CXCL8 IFNG IL10 IL1B IL1R1 SOD2
3
Show member pathways
13.45 CXCL8 IFNG IL10 IL1B IL1R1 TNF
4
Show member pathways
13.29 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
5
Show member pathways
12.91 CXCL8 IL1B IL1R1 IL1RN NLRP3 TNF
6
Show member pathways
12.82 CXCL8 IFNG IL10 IL1B TNF
7
Show member pathways
12.77 CXCL8 IFNG IL1B NLRP3 TNF
8
Show member pathways
12.66 CXCL8 IFNG IL1B TNF
9
Show member pathways
12.61 IFNG IL1B IL1R1 TNF
10
Show member pathways
12.56 IFNG IL10 IL1B IL1R1 TNF
11
Show member pathways
12.55 IFNG IL10 IL1B TNF
12 12.53 IFNG IL10 IL1B IL1RN TNF
13
Show member pathways
12.49 CXCL8 IFNG IL10 IL1B TNF
14
Show member pathways
12.41 IFNG IL10 IL1B TNF
15
Show member pathways
12.33 IFNG IL1B SOD2 TNF
16
Show member pathways
12.32 CXCL8 IFNG IL1B TNF
17
Show member pathways
12.24 IFNG IL10 IL1B TNF
18
Show member pathways
12.23 CXCL8 IFNG IL1B IL1R1 TNF
19 12.22 IFNG IL10 IL1B TNF
20
Show member pathways
12.2 IFNG IL1B NLRP3 TNF
21
Show member pathways
12.14 CXCL8 IFNG IL1B IL1R1 TNF
22 12.12 CXCL8 IL10 IL1B IL1RN TNF
23 12.08 IFNG IL1B IL1R1 TNF
24
Show member pathways
12.08 CXCL8 IFNG IL10 IL1B TNF
25 12.03 IFNG IL1B IL1R1 TNF
26 11.96 IFNG IL10 TNF
27 11.96 CXCL8 IL10 IL1B TNF
28
Show member pathways
11.95 IFNG IL1B IL1R1
29 11.92 CXCL8 IFNG IL1B
30
Show member pathways
11.91 IFNG IL10 IL1B TNF
31 11.91 CXCL8 IFNG IL1B IL1R1 TNF
32 11.88 CXCL8 IL1B TNF
33 11.87 IL1B IL1R1 TNF
34 11.86 CXCL8 IL1B IL1R1 TNF
35
Show member pathways
11.84 IFNG IL1B IL1R1
36 11.83 CXCL8 IFNG IL1B TNF
37 11.81 CXCL8 IFNG IL1B
38
Show member pathways
11.75 CXCL8 IFNG TNF
39 11.74 IFNG IL10 IL1B TNF
40 11.66 CALCA CXCL8 IL1B TNF
41
Show member pathways
11.65 CXCL8 IFNG IL1B TNF
42 11.62 IFNG IL10 IL1B IL1R1 TNF
43 11.6 CXCL8 IL1B TNF
44 11.54 CXCL8 IL10 IL1B NLRP3 TNF
45 11.53 IFNG IL1B TNF
46 11.53 IFNG IL1B TNF
47
Show member pathways
11.47 IL1B IL1R1 TNF
48 11.45 CALCA IFNG IL1B TNF
49 11.42 CXCL8 IFNG IL10 IL1B IL1R1 TNF
50
Show member pathways
11.38 IFNG IL10 TNF

GO Terms for Aseptic Meningitis

Cellular components related to Aseptic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 CALCA CXCL8 IFNG IL10 IL1B IL1RN
2 extracellular region GO:0005576 9.28 CALCA CXCL8 IFNG IL10 IL1B IL1R1

Biological processes related to Aseptic Meningitis according to GeneCards Suite gene sharing:

(show all 42)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.96 CXCL8 IL10 IL1B SOD2
2 aging GO:0007568 9.86 CALCA IL10 SOD2
3 positive regulation of protein phosphorylation GO:0001934 9.85 IFNG IL1B TNF
4 defense response GO:0006952 9.84 CXCL8 NLRP3 TNF
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.83 IL1B NLRP3 TNF
6 cellular response to tumor necrosis factor GO:0071356 9.82 CALCA CD58 CXCL8
7 positive regulation of DNA binding transcription factor activity GO:0051091 9.8 IL10 IL1B TNF
8 immune response GO:0006955 9.8 CXCL8 IFNG IL10 IL1B IL1R1 IL1RN
9 regulation of inflammatory response GO:0050727 9.77 IL1R1 NLRP3 TNF
10 regulation of insulin secretion GO:0050796 9.76 IFNG IL1B TNF
11 cellular response to lipopolysaccharide GO:0071222 9.76 CXCL8 IL10 NLRP3 TNF
12 response to glucocorticoid GO:0051384 9.74 IL10 IL1RN TNF
13 interleukin-12-mediated signaling pathway GO:0035722 9.7 IFNG IL10 SOD2
14 negative regulation of interleukin-6 production GO:0032715 9.69 IL10 TNF
15 positive regulation of protein complex assembly GO:0031334 9.68 IFNG TNF
16 positive regulation of NF-kappaB import into nucleus GO:0042346 9.68 IL1B TNF
17 vasodilation GO:0042311 9.68 CALCA SOD2
18 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.67 IL10 TNF
19 positive regulation of osteoclast differentiation GO:0045672 9.67 IFNG TNF
20 embryonic digestive tract development GO:0048566 9.65 CXCL8 TNF
21 negative regulation of lipid catabolic process GO:0050995 9.65 IL1B TNF
22 negative regulation of growth of symbiont in host GO:0044130 9.64 IL10 TNF
23 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.63 IL1B TNF
24 response to molecule of bacterial origin GO:0002237 9.63 CXCL8 IL10
25 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.62 IL10 IL1RN
26 positive regulation of nitric oxide biosynthetic process GO:0045429 9.62 IFNG IL1B SOD2 TNF
27 positive regulation of chemokine biosynthetic process GO:0045080 9.61 IL1B TNF
28 endothelial cell apoptotic process GO:0072577 9.61 IL10 TNF
29 positive regulation of interleukin-8 production GO:0032757 9.61 CALCA IL1B TNF
30 regulation of establishment of endothelial barrier GO:1903140 9.6 IL1B TNF
31 negative regulation of cytokine secretion involved in immune response GO:0002740 9.58 IL10 TNF
32 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.58 IFNG IL1B TNF
33 interleukin-1 beta production GO:0032611 9.56 IL1B NLRP3
34 fever generation GO:0001660 9.55 IL1B IL1RN
35 positive regulation of fever generation GO:0031622 9.54 IL1B TNF
36 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.54 IL10 IL1B TNF
37 sequestering of triglyceride GO:0030730 9.51 IL1B TNF
38 regulation of receptor activity GO:0010469 9.5 CALCA CXCL8 IFNG IL10 IL1B IL1RN
39 receptor biosynthetic process GO:0032800 9.49 IL10 TNF
40 positive regulation of vitamin D biosynthetic process GO:0060557 9.48 IFNG TNF
41 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.33 IFNG IL1B TNF
42 inflammatory response GO:0006954 9.17 CALCA CXCL8 IL10 IL1B IL1RN NLRP3

Molecular functions related to Aseptic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CXCL8 IFNG IL10 IL1B IL1RN TNF
2 interleukin-1 receptor binding GO:0005149 8.96 IL1B IL1RN

Sources for Aseptic Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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