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MCID: ASP006
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Aspergillosis malady |
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13 drugs, 84 genes, 10 tissues, 1690 related diseases, 17 phenotypes, 119 articles, clinical trials.
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 23MedlinePlus, 2CDC, 44Wikipedia, 22MalaCards See all sources Export this MalaCard |
NIH Rare Diseases: Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.30
MalaCards: Aspergillosis, also known as aspergillosis, unspecified (disorder), is related to allergic bronchopulmonary aspergillosis and hepatitis c. An important gene associated with Aspergillosis is SFTPD (surfactant protein D), and among its related pathways are Bacterial infections in CF airways and IL-6 Pathway. The drugs flucytosine and amphotericin b lipid complex and the compounds ionomycin and ivig have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, brain and heart, and related mouse phenotypes are respiratory system and renal/urinary system. Disease Ontology: An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus aspergillus infecting lungs, brain, kidney,heart, bone, eyes, sinuses, skin and gastrointestinal tract. it is a serious illnesses in people with a weakened immune system.6 MedlinePlus: Aspergillosis is a disease caused by a fungus (or mold) that is very common in the environment. there are different kinds of aspergillosis. one kind is allergic bronchopulmonary aspergillosis (also called abpa). symptoms of abpa include wheezing and coughing. abpa can affect healthy people but it is most common in people with asthma or cystic fibrosis. another kind is invasive aspergillosis, which invades and damages tissues in the body. it usually affects the lungs, but it can also cause infection in other organs and spread throughout the body. it affects people who have immune system problems, such as people who have had a transplant, are taking high doses of steroids, or getting chemotherapy for some cancers. your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, ct scan of the lungs, or examining tissues for signs of the fungus. treatment is with antifungal drugs. centers for disease control and prevention23 CDC: Aspergillus is a common fungus that can be found in indoor and outdoor environments. Most people breathe in Aspergillus spores every day without being affected. Aspergillosis is a disease caused by this fungus and usually occurs in people with lung diseases or weakened immune systems. The spectrum of illness includes allergic reactions, lung infections, and infections in other organs.2 Wikipedia: Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus...44 more... |
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Sources: 2CDC, 6Disease Ontology, 30NIH Rare Diseases, 8DISEASES, 32Novoseek , 23MedlinePlus, 43UMLS, 27NCIt, 24MeSH, 40SNOMED-CT, 19ICD9CM See all sources |
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for aspergillosis Drug clinical trials:Search ClinicalTrials for aspergillosis Search NIH Clinical Center for aspergillosis Search CenterWatch for aspergillosis Inferred drug relations via UMLS/NDF-RT:43 28 amphotericin b, amphotericin b cholesteryl sulfate, amphotericin b lipid complex, amphotericin b liposome, caspofungin, caspofungin acetate, flucytosine, itraconazole, miconazole, miconazole nitrate, miconazole nitrate pwdr [va product], natamycin, voriconazole |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to aspergillosis:22Bone marrow, Brain, Heart, Colon, Kidney, Lung, Skin, Monocytes, T cells, B cells
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to aspergillosis:25 (show all 17)
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Sources: 35PubMed See all sources |
Articles related to aspergillosis:(show top 50) (show all 119)
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Sources: 1BioGPS See all sources |
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Sources: 41Thomson Reuters, 36QIAGEN, 10EMD Millipore, 37R&D Systems, 38Reactome, 3Cell Signaling Technology, 20KEGG See all sources |
Pathways related to aspergillosis according to GeneDecks:(show top 50) (show all 123)
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Sources: 32Novoseek , 9DrugBank, 18HMDB, 42Tocris Bioscience, 34PharmGKB See all sources |
Compounds related to aspergillosis according to GeneDecks:(show top 50) (show all 458)
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Sources: 12Gene Ontology See all sources |
Cellular components related to aspergillosis according to GeneDecks:
Biological processes related to aspergillosis according to GeneDecks:(show top 50) (show all 82)
Molecular functions related to aspergillosis according to GeneDecks:(show all 15)
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