MCID: ASP007
MIFTS: 49

Aspiration Pneumonia malady

Respiratory diseases category
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Summaries for Aspiration Pneumonia

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Disease Ontology:8 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. it is seen in individuals with dysphagia and gastric dysmotility. the disease has symptom tachypnea and has symptom cough.

MalaCards based summary: Aspiration Pneumonia, also known as pneumonia aspiration, is related to pneumonia and pharyngitis, and has symptoms including An important gene associated with Aspiration Pneumonia is ELANE (elastase, neutrophil expressed), and among its related pathways are Selected targets of C EBPbeta and Peptide ligand-binding receptors. The compounds tenidap and sivelestat sodium hydrate have been mentioned in the context of this disorder. Affiliated tissues include colon, lung and testes, and related mouse phenotype immune system.

Wikipedia:65 Aspiration pneumonia is bronchopneumonia that develops due to the entrance of foreign materials into the... more...

Aliases & Classifications for Aspiration Pneumonia

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 44Novoseek, 34MeSH, 57SNOMED-CT, 39NCIt
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Aspiration Pneumonia, Aliases & Descriptions:

Name: Aspiration Pneumonia 8 10 62
 
Pneumonia Aspiration 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:0050152
MeSH34 D011015
SNOMED-CT57 47839005, 422588002
NCIt39 C34932

Related Diseases for Aspiration Pneumonia

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Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.5IL8, LACTB, CRP, ELANE
2pharyngitis30.7LACTB
3bacteremia30.7LACTB, CRP
4mediastinitis30.6CRP
5bronchiectasis30.6IL8, ELANE
6bronchiolitis30.4IL8
7respiratory failure30.2TAC1, LACTB, ELANE
8pancreatitis30.0TAC1, CRP, ELANE
9hypertension29.9ACE, CRP, TAC1
10sepsis29.9LACTB, ELANE, IL8, CRP
11diabetes mellitus29.9TAC1, CRP, ACE
12acute pancreatitis29.9ELANE, CRP, IL8
13septic shock29.6LACTB, CRP, ELANE, IL8
14dysphagia10.6
15capillary leak syndrome10.5ELANE
16pustulosis palmaris et plantaris10.5ELANE
17prostatitis10.5LACTB
18endophthalmitis10.5LACTB
19esophagitis10.4
20sinusitis10.4LACTB
21bronchitis10.4CRP
22bacteriuria10.4CRP
23burns10.3
24achalasia10.3
25laryngitis10.3
26epiglottitis10.3
27laryngotracheitis10.3
28cerebrovascular disease10.3
29hyperostosis10.3
30kawasaki disease10.2CRP, ELANE
31septic arthritis10.2CRP, LACTB
32appendicitis10.2LACTB, CRP
33pelvic inflammatory disease10.2CRP, LACTB
34neutropenia10.2ELANE, LACTB
35periodontal disease10.2CRP, ELANE
36pyelonephritis10.2LACTB, CRP
37osteomyelitis10.2CRP, LACTB
38tonsillitis10.2LACTB, CRP
39alzheimer's disease10.2
40diffuse idiopathic skeletal hyperostosis10.2
41cervicitis10.2
42dementia10.2
43tracheoesophageal fistula10.2
44peritonitis10.1CRP, LACTB
45vasculitis10.1ELANE, CRP
46bronchopulmonary dysplasia10.1ELANE, IL8
47extrinsic allergic alveolitis10.1ELANE, IL8
48arthropathy10.1TAC1, CRP
49adult respiratory distress syndrome10.1IL8, ELANE
50stroke, ischemic10.1CRP, ACE

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to aspiration pneumonia

Symptoms for Aspiration Pneumonia

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Drugs & Therapeutics for Aspiration Pneumonia

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Drug clinical trials:

Search ClinicalTrials for Aspiration Pneumonia

Search NIH Clinical Center for Aspiration Pneumonia

Genetic Tests for Aspiration Pneumonia

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Anatomical Context for Aspiration Pneumonia

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MalaCards organs/tissues related to Aspiration Pneumonia:

32
Colon, Lung, Testes, Brain, Neutrophil, Tongue

Animal Models for Aspiration Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Aspiration Pneumonia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1GLRA1, CRP, IL8, ACE, ELANE

Publications for Aspiration Pneumonia

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Articles related to Aspiration Pneumonia:

(show top 50)    (show all 407)
idTitleAuthorsYear
1
Effect of Early Rehabilitation by Physical Therapists on In-hospital Mortality after Aspiration Pneumonia in the Elderly. (25301440)
2014
2
Clinical features and outcomes of aspiration pneumonia compared with non-aspiration pneumonia: a retrospective cohort study. (24834866)
2014
3
Oral health disparities in older adults: oral bacteria, inflammation, and aspiration pneumonia. (25201541)
2014
4
Aspiration pneumonia after chemo-intensity-modulated radiation therapy of oropharyngeal carcinoma and its clinical and dysphagia-related predictors. (23729173)
2014
5
Propolis-induced descending necrotizing mediastinitis and aspiration pneumonia. (23522239)
2013
6
C-reactive protein as a prognostic factor in elderly patients with aspiration pneumonia. (23845829)
2013
7
Reply: the impact of Candida isolates on the outcome of aspiration pneumonia. (23993764)
2013
8
Constipation and aspiration pneumonia. (22712814)
2012
9
Aspiration pneumonia in dogs: treatment, monitoring, and prognosis. (23532879)
2012
10
Complications of oropharyngeal dysphagia: aspiration pneumonia. (23052002)
2012
11
Acute pancreatitis and aspiration pneumonia after administration of synthetic human secretin (with video). (21272872)
2011
12
Risk factors for aspiration pneumonia in frail older people: a systematic literature review. (21450240)
2011
13
Blockade of neutrophil responses in aspiration pneumonia via ELR-CXC chemokine antagonism does not predispose to airway bacterial outgrowth. (19751843)
2010
14
High incidence of false-positive Aspergillus galactomannan test results in patients with aspiration pneumonia. (19470024)
2009
15
Definitive techniques for intractable aspiration pneumonia. (16707166)
2006
16
Differences in the features of aspiration pneumonia according to site of acquisition: community or continuing care facility. (16460382)
2006
17
Squalene aspiration pneumonia in children: radiographic and CT findings as the first clue to diagnosis. (15806404)
2005
18
Prevention of aspiration pneumonia in nursing home patients. (15614685)
2005
19
Significance of chronic cough as a defence mechanism or a symptom in elderly patients with aspiration and aspiration pneumonia. (15640344)
2005
20
Aspiration pneumonia. (14989729)
2004
21
Epidemiology and impact of aspiration pneumonia in patients undergoing surgery in Maryland, 1999-2000. (12847385)
2003
22
Aspiration pneumonia associated with a giant epiglottic cyst after cardiac surgery. (12826565)
2003
23
Laryngotracheal separation for intractable aspiration pneumonia in neurologically impaired children: experience with 11 cases. (12778406)
2003
24
ACE inhibitors and its usefulness in the prevention of aspiration pneumonia in chronic cerebrovascular disease patients with asymptomatic swallowing dysfunction]. (12474296)
2002
25
Risk factors of aspiration pneumonia in Alzheimer's disease patients. (11490146)
2001
26
Aspiration pneumonia secondary to giant cervical osteophyte formation (diffuse idiopathic skeletal hyperostosis or Forrestier's disease): a case report. (9824035)
1998
27
Antibiotics for the treatment of aspiration pneumonia. (9491053)
1998
28
New strategies for aspiration pneumonia. (9475237)
1997
29
Olive oil aspiration pneumonia (lipoid) in children. (9171848)
1997
30
Enteral feeding associated gastroesophageal reflux and aspiration pneumonia: a review. (9063023)
1996
31
Actionstat. Aspiration pneumonia. (8975192)
1996
32
Treatment of aspiration pneumonia with low-dose methylprednisolone and antibiotics]. (7699968)
1995
33
Postgastrectomy aspiration pneumonia. (7842777)
1995
34
Effect of ventilation with positive end-expiratory pressure on the development of lung damage in experimental acid aspiration pneumonia in the rabbit. (1613190)
1992
35
Functional changes of alveolar macrophages in carragheenan-induced aspiration pneumonia model mice. (1282398)
1992
36
Bilateral vocal cord teflon injection. An ineffective treatment for recurrent aspiration pneumonia. (2007015)
1991
37
Aspiration pneumonia and coma--an unusual presentation of dystrophic myotonia. (3779503)
1986
38
Aspiration pneumonia: a review. (3513497)
1986
39
Aspiration pneumonia caused by fibrous material in rats. (3803436)
1986
40
Aspiration pneumonia in patients fed through nasoenteral tubes. (3084401)
1986
41
Pathology of aspiration pneumonia in mice. (4065213)
1985
42
Tracheoesophageal fistula secondary to esophageal carcinoma presenting with aspiration pneumonia. (3999155)
1985
43
Aspiration pneumonia from povidone-iodine (Betadine): report of case. (6936546)
1981
44
Pulmonary effects of aspiration pneumonia. (752747)
1978
45
Experimental acid-aspiration pneumonia in the rabbit. A pathologic and morphometric study. (1006955)
1976
46
Neonatal milk aspiration pneumonia--a possible additional use for continuous positive airway pressure. (4585443)
1973
47
The view box. Pharyngeal (Zenker's) diverticulum and aspiration pneumonia. (4627662)
1972
48
Aspiration pneumonia in gnotobiotic piglets. (5813557)
1969
49
Milk-aspiration pneumonia in human and animal subjects. (13030048)
1953
50
The role of delayed gastric emptying time in the etiology of aspiration pneumonia. (18882818)
1948

Variations for Aspiration Pneumonia

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Expression for genes affiliated with Aspiration Pneumonia

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Expression patterns in normal tissues for genes affiliated with Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for genes affiliated with Aspiration Pneumonia

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Compounds for genes affiliated with Aspiration Pneumonia

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Compounds related to Aspiration Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1tenidap44 2811.0ELANE, CRP
2sivelestat sodium hydrate4410.0IL8, ELANE
3curosurf4410.0ELANE, IL8
4sivelestat4410.0ELANE, IL8
5survanta4410.0ELANE, IL8
6tlck4410.0IL8, ELANE
7cilomilast4410.0IL8, ELANE
8ulinastatin449.9ELANE, IL8
9polysulfone449.9ELANE, CRP
10aebsf449.9IL8, ELANE
11chymostatin449.8ELANE, ACE
12nedocromil sodium449.8TAC1, IL8
13fosinopril44 1110.8ACE, CRP
14quinapril44 50 1111.8ACE, CRP
15anaphylatoxin449.7IL8, ELANE
16ramipril44 1110.7CRP, ACE
17valsartan44 61 28 1112.7CRP, ACE
18gm-csf44 2810.7IL8, ELANE
19beta-lactam449.7LACTB, ELANE
20perindopril44 50 1111.7CRP, ACE
21telmisartan44 28 1111.7ACE, CRP
22vancomycin44 1110.7ELANE, LACTB
23thiorphan44 28 1111.7TAC1, ACE
24atenolol44 50 28 24 1113.6ACE, CRP
25hydrochlorothiazide44 28 50 24 1113.6CRP, ACE
26fluticasone propionate44 50 61 1112.6IL8, ELANE
27gabexate mesilate449.6IL8, CRP, ELANE
28sulfasalazine28 44 50 1112.6CRP, IL8
29moxifloxacin44 1110.6IL8, LACTB
30ceftriaxone44 1110.6CRP, LACTB
31neopterin449.6CRP, ELANE, IL8
32enalapril44 50 1111.5TAC1, ACE
33endotoxin449.5CRP, ELANE, IL8
34chlorine44 2410.5GLRA1, ACE, ELANE
35nitroglycerin44 1110.5ELANE, ACE, CRP
36fmlp449.4TAC1, ELANE, IL8
37methacholine44 50 1111.4CRP, TAC1, IL8
38phosphoramidon44 1110.4ACE, TAC1, ELANE
398-isoprostane449.4IL8, CRP
40captopril44 61 50 28 1113.4TAC1, ACE, ELANE
41clarithromycin44 1110.4LACTB, IL8
42aspirin44 50 28 2412.4ACE, CRP, ELANE
43digoxin44 61 50 24 1113.3ACE, TAC1
44nifedipine44 28 50 1112.3ACE, GLRA1, TAC1
45chloramphenicol44 2 50 1112.1ELANE, LACTB, CRP
46azithromycin44 1110.1IL8, CRP, LACTB
47clopidogrel44 50 24 1112.1CRP, ACE
48prostacyclin448.9ACE, CRP, TAC1, ELANE
49norepinephrine44 24 1110.9ELANE, ACE, CRP, TAC1
50acetylcholine44 50 28 24 1112.9CRP, ELANE, ACE, TAC1

GO Terms for genes affiliated with Aspiration Pneumonia

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Cellular components related to Aspiration Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.4TAC1, CRP, IL8, ACE
2extracellular regionGO:0055767.7TAC1, CRP, IL8, ACE, ELANE

Biological processes related to Aspiration Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:0324969.6TAC1, ELANE
2neuropeptide signaling pathwayGO:0072189.2TAC1, GLRA1
3regulation of blood pressureGO:0082179.2TAC1, ACE
4inflammatory responseGO:0069549.0TAC1, CRP, IL8

Molecular functions related to Aspiration Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endopeptidase activityGO:0041759.2ACE, ELANE
2protein bindingGO:0055157.6TAC1, GLRA1, CRP, IL8, ACE, ELANE

Products for genes affiliated with Aspiration Pneumonia

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Sources for Aspiration Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet