ASTHMA
MCID: AST005
MIFTS: 82

Asthma (ASTHMA) malady

Categories: Genetic diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Asthma

Aliases & Descriptions for Asthma:

Name: Asthma 54 38 12 50 66 66 52 41 3 42 14 69
Chronic Obstructive Asthma 12 52 69
Bronchial Hyperreactivity 12 52 69
Asthma, Diminished Response to Antileukotriene Treatment in 54 13
Chronic Obstructive Asthma with Acute Exacerbation 12
Chronic Obstructive Asthma with Status Asthmaticus 12
Asthma, Protection Against 54
Asthma, Susceptibility to 29
Asthma, Exercise-Induced 69
Exercise Induced Asthma 12
Exercise-Induced Asthma 12
Asthma Exercise-Induced 52
Asthma, Nocturnal 54
Bronchial Asthma 66

Classifications:



Summaries for Asthma

MedlinePlus : 41 asthma is a chronic disease that affects your airways. your airways are tubes that carry air in and out of your lungs. if you have asthma, the inside walls of your airways become sore and swollen. that makes them very sensitive, and they may react strongly to things that you are allergic to or find irritating. when your airways react, they get narrower and your lungs get less air. symptoms of asthma include wheezing coughing, especially early in the morning or at night chest tightness shortness of breath not all people who have asthma have these symptoms. having these symptoms doesn't always mean that you have asthma. your doctor will diagnose asthma based on lung function tests, your medical history, and a physical exam. you may also have allergy tests. when your asthma symptoms become worse than usual, it's called an asthma attack. severe asthma attacks may require emergency care, and they can be fatal. asthma is treated with two kinds of medicines: quick-relief medicines to stop asthma symptoms and long-term control medicines to prevent symptoms. nih: national heart, lung, and blood institute

MalaCards based summary : Asthma, also known as chronic obstructive asthma, is related to acute chest syndrome and glucocorticoid resistance, and has symptoms including recurring periods of wheezing (a whistling sound while breathing), chest tightness and shortness of breath. An important gene associated with Asthma is IL13 (Interleukin 13), and among its related pathways/superpathways are Asthma and Innate Immune System. The drugs Accolate and Advair have been mentioned in the context of this disorder. Affiliated tissues include Lung, lung and t cells, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has symptom recurring periods of wheezing (a whistling sound while breathing), has symptom chest tightness, has symptom shortness of breath, has symptom mucus production and has symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

NIH Rare Diseases : 50 asthma is a breathing disorder that affects the airways. people with this condition experience recurrent swelling and narrowing of the airways of the lungs which is associated with wheezing, shortness of breath, chest tightness, and coughing. most affected people have episodes of symptoms ("asthma attacks") followed by symptom-free periods; however, some may experience persistent shortness of breath in between attacks. asthma is considered a complex or multifactorial condition that is likely due to a combination of multiple genetic, environmental, and lifestyle factors. many people with asthma have a personal or family history of allergies, such as hay fever or eczema. having a family member with asthma is associated with an increased risk of developing the condition. treatment generally includes various medications, both to prevent asthma attacks and to provide quick relief during an attack. last updated: 2/28/2016

OMIM : 54 Bronchial asthma is the most common chronic disease affecting children and young adults. It is a complex genetic... (600807) more...

CDC : 3 Asthma is a disease that affects your lungs. It causes repeated episodes of wheezing, breathlessness, chest tightness, and nighttime or early morning coughing. Asthma can be controlled by taking medicine and avoiding the triggers that can cause an attack. You must also remove the triggers in your environment that can make your asthma worse.

Novus Biologicals : 53 Asthma is a chronic lung disease that causes inflammation, thickening and narrowing of airways, as well as an overproduction of mucus. More than 300 million people worldwide suffer from asthma. Asthma symptoms include wheezing, shortness of breath, coughing and tightness of the chest. Interleukin 13 (IL-13) is the key effector cytokine in asthma. IL-13 stimulates airway fibrosis via action of matrix metalloproteinases (MMPs) on tumor transforming growth factor beta (TGN-beta), and also promotes epithelial damage, mucus production and an increased concentration of eosinophils. The inflammatory response characteristic of asthma is augmented by the production of IL-13 and other TH2 cytokines.

UniProtKB/Swiss-Prot : 66 Asthma: The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with wheezing due to spasmodic contraction of the bronchi.

Wikipedia : 71 Asthma is a common long term inflammatory disease of the airways of the lungs. It is characterized by... more...

Related Diseases for Asthma

Diseases in the Asthma family:

Asthma 2 Asthma 1
Asthma, Phf11-Related

Diseases related to Asthma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 461)
id Related Disease Score Top Affiliating Genes
1 acute chest syndrome 30.8 ADRB2 CCL11 CYSLTR1 IL13 IL4 IL5
2 glucocorticoid resistance 30.8 ALOX5 CCL11 HAVCR1 IL13 IL4 IL4R
3 pulmonary tuberculosis 29.9 CCL11 IL13 IL4 IL4R IL5 RNASE3
4 allergic asthma 12.4
5 asthma, aspirin-induced 12.3
6 intrinsic asthma 12.2
7 asthma 1 12.2
8 asthma 2 12.2
9 cough variant asthma 12.1
10 asthma-related traits 7 12.1
11 asthma susceptibility 5 12.1
12 asthma-related traits 3 12.0
13 asthma-related traits 6 12.0
14 asthma-related traits 4 12.0
15 asthma, phf11-related 11.7
16 asthma susceptibility, ccl11-related 11.7
17 asthma susceptibility, hla-g-related 11.7
18 asthma susceptibility, il13-related 11.7
19 asthma susceptibility, muc7-related 11.7
20 asthma-related traits 8 11.7
21 asthma susceptibility, pla2g7-related 11.7
22 asthma susceptibility, scgb3a2-related 11.7
23 asthma susceptibility, tnf-related 11.7
24 asthma susceptibility, adrb2-related 11.7
25 asthma susceptibility, hnmt related 11.6
26 status asthmaticus 11.6
27 aspergillosis 11.2
28 atopy 11.2
29 allergic bronchopulmonary aspergillosis 11.2
30 allergic rhinitis 11.1
31 dermatitis 11.1
32 atopic dermatitis 11.1
33 lung disease 11.0
34 churg-strauss syndrome 11.0
35 byssinosis 11.0
36 gastroesophageal reflux 11.0
37 influenza 11.0
38 chronic eosinophilic pneumonia 11.0
39 igg4-related disease 11.0
40 eosinophilic granulomatosis with polyangiitis 11.0
41 pollen allergy 11.0
42 plastic bronchitis 11.0
43 bronchiolitis obliterans 11.0
44 peanut allergy 11.0
45 platelet-activating factor acetylhydrolase deficiency 11.0
46 silicosis 10.9
47 eosinophilic cystitis 10.9
48 latex allergy 10.9
49 atopic dermatitis 3 10.7
50 nemaline myopathy 2, autosomal recessive 10.7 ADRB2 ALOX5 CCL11 CHIA CYSLTR1 HAVCR1

Comorbidity relations with Asthma via Phenotypic Disease Network (PDN):


Acute Cystitis Heart Disease

Graphical network of the top 20 diseases related to Asthma:



Diseases related to Asthma

Symptoms & Phenotypes for Asthma

Symptoms by clinical synopsis from OMIM:

600807

Clinical features from OMIM:

600807

Symptoms:

12
  • recurring periods of wheezing (a whistling sound while breathing)
  • chest tightness
  • shortness of breath
  • mucus production
  • coughing

Human phenotypes related to Asthma:

32
id Description HPO Frequency HPO Source Accession
1 asthma 32 HP:0002099

UMLS symptoms related to Asthma:


coughing, cyanosis, dyspnea, snoring, spasm, wheezing, expiratory wheeze, labored breathing

MGI Mouse Phenotypes related to Asthma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 ADRB2 ALOX5 CCL11 HLA-G IL13 IL4
2 immune system MP:0005387 9.8 PHF11 PLA2G7 TNF ADRB2 ALOX5 CCL11
3 respiratory system MP:0005388 9.28 CCL11 CYSLTR1 IL13 IL4 IL4R IL5

Drugs & Therapeutics for Asthma

FDA approved drugs:

(show all 16)
id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Accolate 17 ZAFIRLUKAST AstraZeneca Approved September 1999|Approved October 1996
2
Advair 17 FLUTICASONE PROPIONATE; SALMETEROL XINAFOATE GlaxoSmithKline Approved August 2000
3
Alvesco 17 CICLESONIDE Nycomed Approved January 2008
4
Arnuity Ellipta 17 FLUTICASONE FUROATE GlaxoSmithKline Approved August 2014
5
Azmacort 17 TRIAMCINOLONE ACETONIDE Rhone Poulenc Rorer Approved November 1996
6
Dulera 17 FORMOTEROL FUMARATE; MOMETASONE FUROATE Merck Approved June 2010
7
Flovent Rotadisk 17 FLUTICASONE PROPIONATE GlaxoSmithKline Approved November 1997
8
Foradil Aerolizer 17 FORMOTEROL FUMARATE Novartis Approved February 2001 (asthma, bronchospasm); September 2001 (COPD)
9
Metaprotereol Sulfate 17 METAPROTERENOL SULFATE Morton Grove Pharmaceuticals Approved March 1997
10
Nucala 17 MEPOLIZUMAB GlaxoSmithKline Approved November 2015
11
Qvar 17 BECLOMETHASONE DIPROPIONATE Ivax Approved May 2002
12
Rayos 17 PREDNISONE Horizon Pharma Approved July of 2012
13
Serevent 17 SALMETEROL XINAFOATE GlaxoSmithKline Approved September 1997
14
Singulair 17 MONTELUKAST SODIUM Merck Approved February 1998
15
Xolair 17 OMALIZUMAB Genentech Approved June 2003
16
Zyflo 17 ZILEUTON Abbott Laboratories Approved January 1997

Drugs for Asthma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 822)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51333-22-3 63006 5281004
2
Ipratropium Approved Phase 4,Phase 3,Phase 2,Phase 1 22254-24-6, 60205-81-4 43232
3
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
4
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
5
Procaterol Approved Phase 4,Phase 3,Phase 2,Phase 1 72332-33-3 688561
6
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 299-42-3 9294
7
Guaifenesin Approved, Vet_approved Phase 4,Phase 2,Phase 1 93-14-1 3516
8
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 90-82-4 7028
9
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 158966-92-8 5281040
10
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 2 103577-45-3 3883
11
Benzocaine Approved Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
12
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
13
Etomidate Approved Phase 4 33125-97-2 36339 667484
14
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 437-38-7 3345
15
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
16
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
17
Remifentanil Approved Phase 4 132875-61-7 60815
18
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 242138-07-4
19
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
21
Terbutaline Approved Phase 4,Phase 3,Phase 2,Phase 1 23031-25-6 5403
22
Bambuterol Approved Phase 4,Phase 1 81732-65-2, 81732-46-9 54766
23
Capsaicin Approved Phase 4,Phase 2,Early Phase 1 404-86-4 1548943
24
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 75614-87-8, 51-45-6 774
25
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
26
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2 26787-78-0 33613 2171
27
Cetirizine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 83881-51-0 2678
28
Epoprostenol Approved Phase 4,Phase 3 61849-14-7, 35121-78-9 5280427 5282411
29
Cilostazol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 73963-72-1 2754
30
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
31
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 69-65-8 453 6251
32
Ciclesonide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 126544-47-6, 141845-82-1 444033
33
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 55185 53477736 447043
34
Menthol Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 2216-51-5 16666
35
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-23-7 5754 657311
36
Citalopram Approved Phase 4 59729-33-8 2771
37
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7487-88-9 24083
38
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 58-61-7 60961
39
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
40
Theophylline Approved Phase 4,Phase 3,Phase 2,Phase 1 58-55-9 2153
41
Fenoterol Approved Phase 4,Phase 3,Phase 1 13392-18-2 3343
42
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 1 525-66-6 4946
43
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
44
Levocetirizine Approved Phase 4,Phase 3,Phase 1 130018-77-8
45
Azelastine Approved Phase 4,Phase 3,Phase 2 58581-89-8 2267
46
Aminophylline Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 317-34-0 9433
47
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 378-44-9 9782
48
Ethanol Approved Phase 4,Phase 2,Phase 1 64-17-5 702
49
Norepinephrine Approved Phase 4 51-41-2 439260
50
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554

Interventional clinical trials:

(show top 50) (show all 5012)
id Name Status NCT ID Phase
1 Assessing Decision Maker Tools for Asthma: the Asthma APGAR Unknown status NCT01446315 Phase 4
2 Improving Asthma Control in the Real World: A Systematic Approach to Improving Dulera Adherence Unknown status NCT02045875 Phase 4
3 Optimization of Inhaled Corticosteroid Treatment in Adult Patients With Asthma Guided by Exhaled NO Measurement at Home Unknown status NCT01783132 Phase 4
4 Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma Unknown status NCT00576069 Phase 4
5 Vitamin D for the Treatment of Severe Asthma Unknown status NCT00712205 Phase 4
6 Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations Unknown status NCT01497691 Phase 4
7 Efficacy and Safety of Activation Energy Serum (AES) Versus Placebo in Persistent Asthma. Unknown status NCT01939951 Phase 4
8 Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital Unknown status NCT02053402 Phase 4
9 A Pilot Study Involving an Asthma Management Program for Inner-city Early Head Start Children Unknown status NCT00624429 Phase 4
10 Inflammatory, Functional and Image Composite Measure to Define Asthma Control Unknown status NCT00597064 Phase 4
11 Assessment of Utility of Exhaled Nitric Oxide Measurement for Treatment Monitoring in Children With Asthma Unknown status NCT00500253 Phase 4
12 Evaluation of Efficacy of House Dust Mite Immunotherapy in Children With Bronchial Asthma Unknown status NCT00496574 Phase 4
13 Fluticasone/Salmeterol (FP/SM) Versus Double the Dose Fluticasone (FP) in Patients With Mild to Moderate Asthma Unknown status NCT00830505 Phase 4
14 A Comparison of Mometasone to Advair in Patients With Milder Persistent Asthma Unknown status NCT00461812 Phase 4
15 Efficacy and Safety Study of Procaterol Hydrochloride to Treat Patients With Cough Variant Asthma (CVA) Unknown status NCT01170429 Phase 4
16 Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma Unknown status NCT01584804 Phase 4
17 Effects of Leukotriene Modulator Montelukast on Cough Variant Asthma Unknown status NCT01404013 Phase 4
18 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4
19 A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy. Unknown status NCT00237068 Phase 4
20 Effect of Dexmedetomidine on Levels of Plasma Inflammatory Factor in Asthma Patients Undergoing General Anesthesia Unknown status NCT02289391 Phase 4
21 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4
22 Effect of Specific Immunotherapy to Dust Mites in Children With Asthma Unknown status NCT00496561 Phase 4
23 Onset of Action of Advair Hydrofluoroalkane (HFA) 115/21 in Comparison to Symbicort Pressurised Metered-Dose Inhalers (pMDI) 160/4.5 Measured by Impulse Oscillometry (IOS) Unknown status NCT00867737 Phase 4
24 Effect of Xolair on Airway Hyperresponsiveness Unknown status NCT00208234 Phase 4
25 Extra-fine Formoterol/Beclomethasone in Asthmatic Crisis Unknown status NCT02345993 Phase 4
26 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4
27 Sublingual Immunotherapy With House Dust Mite Extract in Asthmatic Children Unknown status NCT00172341 Phase 4
28 Concentrations of Salmeterol in Blood and Urine Unknown status NCT00914901 Phase 4
29 Terbutaline Concentrations in Blood and Urine Unknown status NCT00914797 Phase 4
30 Concentrations of Formoterol in Blood and Urine Unknown status NCT00914654 Phase 4
31 Rapid Onset Action of Salbutamol Versus Formoterol Unknown status NCT00900874 Phase 4
32 Effects of Montelukast in Asthmatic Children With and Without Food Allergy Unknown status NCT01618929 Phase 4
33 Efficacy of Bronchial Thermoplasty in Korean Unknown status NCT02031263 Phase 4
34 A Pilot Efficacy Study of Inhaled Albuterol Delivered With Akita Breath Control Unknown status NCT00385359 Phase 4
35 Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids Unknown status NCT00397267 Phase 4
36 The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma Unknown status NCT02002754 Phase 4
37 mRNA Expression as a Biomarker of Omalizumab Response Unknown status NCT01584687 Phase 4
38 Predicting the Clinical Response to Omalizumab With Anti-IgE Ab Response or Syk Expression in Basophils Unknown status NCT02023151 Phase 4
39 Efficacy and Safety of LAIS® Mites Sublingual Tablets Unknown status NCT02277483 Phase 4
40 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4
41 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4
42 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4
43 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4
44 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4
45 Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function Unknown status NCT01466712 Phase 4
46 Preterm Infant Inhaled Albuterol Dosing Unknown status NCT02447250 Phase 4
47 Comparing Fluticasone-Salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep Unknown status NCT00731770 Phase 4
48 Airway Clearance for Prevention of COPD Exacerbation Unknown status NCT00181207 Phase 4
49 Effectiveness of Blood Clot Medication With Concomitant Blood Pressure Medication Unknown status NCT00424281 Phase 4
50 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4

Search NIH Clinical Center for Asthma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Asthma cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Asthma:
Bone marrow-derived mesenchymal stem cells for severe refractory asthma
Embryonic/Adult Cultured Cells Related to Asthma:
Mouse bone marrow-derived mesenchymal stem cells (family) PMIDs: 21653527 20801416

Cochrane evidence based reviews: asthma

Genetic Tests for Asthma

Genetic tests related to Asthma:

id Genetic test Affiliating Genes
1 Asthma, Susceptibility to 29
2 Asthma 29

Anatomical Context for Asthma

MalaCards organs/tissues related to Asthma:

39
Lung, T Cells, Testes, Neutrophil, Smooth Muscle, Heart, Monocytes
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Asthma:
id Tissue Anatomical CompartmentCell Relevance
1 Lung Trachea Airway Smooth Muscle Cells Potential therapeutic candidate, affected by disease

Publications for Asthma

Articles related to Asthma:

(show top 50) (show all 6470)
id Title Authors Year
1
The Calculated Risk of Childhood Asthma From Severe Bronchiolitis. ( 28065346 )
2017
2
Association of atopy phenotypes with new development of asthma and bronchial hyperresponsiveness in school-aged children. ( 28364972 )
2017
3
Persistent asthma phenotype related with late-onset, high atopy, and low socioeconomic status in school-aged Korean children. ( 28231776 )
2017
4
An orally active geranyl acetophenone attenuates airway remodeling in a murine model of chronic asthma. ( 28089919 )
2017
5
IL-37 a New IL-1 Family Member Emerges as a Key Suppressor of Asthma Mediated by Mast Cells. ( 27982737 )
2017
6
Parents' Childhood Socioeconomic Circumstances are Associated with their Children's Asthma Outcomes. ( 28089871 )
2017
7
Respiratory reactance in children aged three to fiveA years with postinfectious bronchiolitis obliterans is higher than in those with asthma. ( 27743492 )
2017
8
Staphylococcus aureus colonization isA associated with increased inhaled corticosteroid requirements in patients with atopic dermatitis and asthma. ( 28526276 )
2017
9
IL-23 Gene and Protein Expression in Childhood Asthma. ( 28341820 )
2017
10
Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma. ( 28530840 )
2017
11
Maternal Folate Intake during Pregnancy and Childhood Asthma. ( 28084816 )
2017
12
#Asthma #Inhaler: Evaluation of visual social media depictions of inhalers and spacers. ( 28533122 )
2017
13
Infection-mediated asthma: etiology, mechanisms and treatment options, with focus on Chlamydia pneumoniae and macrolides. ( 28526018 )
2017
14
The Natural Course of Atopic Dermatitis and the Association with Asthma. ( 28063089 )
2017
15
Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma. ( 28528200 )
2017
16
Wheezing, asthma, and atopy in premature infants at 2 years of age. ( 28425254 )
2017
17
Asthma and early herniated intervertebral disc disease. ( 28498027 )
2017
18
Pediatric nurse practitioners effective in teaching providers the Asthma Action Plan using simulation. ( 28087087 )
2017
19
Allergen immunotherapy for the treatment of allergic rhinitis and/or asthma: an umbrella review. ( 28495938 )
2017
20
Systemic and mucosal pre-administration of recombinant Helicobacter pylori neutrophil-activating protein prevents ovalbumin-induced allergic asthma in mice. ( 28087613 )
2017
21
Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma. ( 28024734 )
2017
22
Bupleurum chinense extract ameliorates an OVA-induced murine allergic asthma through the reduction of the Th2 and Th17 cytokines production by inac