MCID: AST006
MIFTS: 42

Astigmatism malady

Eye diseases category
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Summaries for Astigmatism

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Disease Ontology:8 A refractive error characterized by the optics of the eye to focus a point object into a sharp focused image on the retina, has symptom blurred vision.

MalaCards based summary: Astigmatism is related to keratoconus and irregular astigmatism, and has symptoms including An important gene associated with Astigmatism is VSX1 (visual system homeobox 1). The compound sulfate have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related mouse phenotypes are digestive/alimentary and vision/eye.

Wikipedia:65 An optical system with astigmatism is one where rays that propagate in two perpendicular planes have... more...

Description from OMIM:46 603047

Aliases & Classifications for Astigmatism

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 27ICD9CM, 46OMIM, 25ICD10
See all sources

Astigmatism, Aliases & Descriptions:

Name: Astigmatism 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:11782
MeSH34 D001251
ICD9CM27 367.2
OMIM46 603047
ICD1025 H52.2

Related Diseases for Astigmatism

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Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to astigmatism

Symptoms for Astigmatism

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Clinical features from OMIM:

603047

Drugs & Therapeutics for Astigmatism

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Drug clinical trials:

Search ClinicalTrials for Astigmatism

Search NIH Clinical Center for Astigmatism

Genetic Tests for Astigmatism

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Anatomical Context for Astigmatism

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MalaCards organs/tissues related to Astigmatism:

32
Eye, Retina, Endothelial, Testes

Animal Models for Astigmatism or affiliated genes

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MGI Mouse Phenotypes related to Astigmatism:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5FGFR3, DNAH5, ASPH
2MP:00053918.4FGFR3, VSX1, NYX, FBXO7
3MP:00053828.2ASPH, DNAH5, FGFR3

Publications for Astigmatism

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Articles related to Astigmatism:

(show top 50)    (show all 641)
idTitleAuthorsYear
1
Evaluation of femtosecond laser-assisted and manual clear corneal incisions and their effect on surgically induced astigmatism and higher-order aberrations. (25325892)
2014
2
Time course of induced astigmatism after canaloplasty. (24370811)
2014
3
Combined special capsular tension ring and toric IOL implantation for management of post-DALK high regular astigmatism with subluxated traumatic cataract. (25116780)
2014
4
Correcting lenticular astigmatism by reinstating the correct neuromuscular message. (23639283)
2013
5
Prevalence of corneal astigmatism before cataract surgery in Caucasian patients. (24366768)
2013
6
Predicting ocular residual astigmatism using corneal and refractive parameters: a myopic eye study. (23621376)
2013
7
Developmental changes in anterior corneal astigmatism in Tohono O'odham Native American infants and children. (23510314)
2013
8
Effect of steepest-meridian clear corneal incision for reducing preexisting corneal astigmatism using a meridian-marking method or surgeon's intuition. (24157251)
2013
9
Wearing time as a measure of success of scleral lenses for patients with irregular astigmatism. (24145901)
2013
10
Effects of induced astigmatism on foot placement strategies when stepping onto a raised surface. (23717414)
2013
11
Astigmatism and its role in emmetropization. (23644224)
2013
12
Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser. (23158680)
2013
13
Modern management of astigmatism. (23221886)
2013
14
Heritability of refractive astigmatism: a population-based twin study among 63- to 75-year-old female twins. (23950154)
2013
15
Prevalence of corneal astigmatism before cataract surgery in Chinese patients. (23141077)
2013
16
Astigmatism in patients with idiopathic congenital nystagmus. (23456100)
2013
17
Effects of pterygium surgery on front and back corneal astigmatism. (23036543)
2012
18
Perceptual adaptation to the correction of natural astigmatism. (23050021)
2012
19
Corneal astigmatism after micro-incision cataract operation. (22486146)
2012
20
Iris-fixated toric phakic intraocular lens for myopic astigmatism. (22613689)
2012
21
Contribution of posterior corneal astigmatism to total corneal astigmatism. (23069271)
2012
22
Time course of refractive and corneal astigmatism after laser in situ keratomileusis for moderate to high astigmatism. (22814047)
2012
23
Postoperative astigmatism in the second eye undergoing cataract surgery. (21402984)
2011
24
Comparison of astigmatism correction using shorter arc length 90A^/120A^ asymmetric intacs severe keratoconus versus 150A^ single-segment intacs severe keratoconus in asymmetric keratoconus. (21926565)
2011
25
Prevalence of astigmatism in a paediatric population with malocclusions. (21668278)
2011
26
Correction of astigmatism during cataract surgery: toric intraocular lens compared to peripheral corneal relaxing incisions. (20873707)
2011
27
Keratometry measurements, corneal astigmatism and irregularity in a normal population: the Tehran Eye Study. (21205266)
2010
28
Intraocular omni-focal lens with increased tolerance to decentration and astigmatism. (20199017)
2010
29
Prevalence of astigmatism in Native American infants and children. (20386351)
2010
30
Collagen copolymer toric posterior chamber phakic intraocular lenses to correct high myopic astigmatism. (20656159)
2010
31
Toric intraocular lens versus opposite clear corneal incisions to correct astigmatism in eyes having cataract surgery. (19781484)
2009
32
Postoperative astigmatism and axis stability after implantation of the STAAR Toric Implantable Collamer Lens. (19507791)
2009
33
Femtosecond laser arcuate keratotomy for the correction of high astigmatism after keratoplasty. (19395035)
2009
34
Changes in astigmatism after surgery for epiblepharon in highly astigmatic children: a controlled study. (18835734)
2008
35
Management of irregular astigmatism following rotationally disoriented free cap after LASIK. (18500089)
2008
36
Astigmatism terminology. (18721693)
2008
37
Astigmatism, its measurement, and fundamental optical properties. (17992838)
2007
38
Limbal relaxing incisions to correct corneal astigmatism during phacoemulsification. (17523513)
2007
39
Active cyclotorsion error correction during LASIK for myopia and myopic astigmatism with the NIDEK EC-5000 CX III laser. (18047004)
2007
40
Corneal astigmatism with upper eyelid gold weight implantation using the combined high pretarsal and levator fixation technique. (17881989)
2007
41
Bungee cord-induced corneal lacerations correcting for myopic astigmatism. (17586399)
2007
42
Strategic planning in topography-guided ablation of irregular astigmatism after laser refractive surgery. (16128335)
2005
43
Modified astigmatism dial diagram for locating eccentric fixation in patients with central scotoma. (12749291)
2003
44
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
45
Refractive error changes in mixed astigmatism. (10768025)
1999
46
Epiblepharon of the lower eyelid: classification and association with astigmatism. (9510654)
1997
47
Disciform keratitis causing severe irregular astigmatism. (8743008)
1996
48
Escalation of keratospeak: regular and irregular astigmatism. (2248932)
1990
49
Visual acuity, refractive error, and astigmatism following corneal transplantation for pseudophakic bullous keratopathy. (3909036)
1985
50
Can Staphyloma Posticum be induced by Astigmatism? (25258805)
1875

Variations for Astigmatism

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Expression for genes affiliated with Astigmatism

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Expression patterns in normal tissues for genes affiliated with Astigmatism

Search GEO for disease gene expression data for Astigmatism.

Pathways for genes affiliated with Astigmatism

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Compounds for genes affiliated with Astigmatism

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Sources:
44Novoseek, 24HMDB
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Compounds related to Astigmatism according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1sulfate44 2410.4FGFR3, CHST6

GO Terms for genes affiliated with Astigmatism

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Biological processes related to Astigmatism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1visual perceptionGO:0076019.7VSX1, NYX
2response to stimulusGO:0508969.4VSX1, NYX
3regulation of protein stabilityGO:0316479.0ASPH, FBXO7

Products for genes affiliated with Astigmatism

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  • Antibodies
  • Proteins
  • Lysates

Sources for Astigmatism

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet