MCID: AST006
MIFTS: 41

Astigmatism malady

Eye diseases category

Summaries for Astigmatism

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63Wikipedia, 46OMIM, 32MalaCards
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Wikipedia:63 An optical system with astigmatism is one where rays that propagate in two perpendicular planes have... more...

MalaCards: Astigmatism, also known as astigmatism, unspecified, is related to irregular astigmatism and keratoconus. An important gene associated with Astigmatism is VSX1 (visual system homeobox 1). Affiliated tissues include eye, endothelial and testes, and related mouse phenotype vision/eye.

Description from OMIM:46 603047

Aliases & Classifications for Astigmatism

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 46OMIM, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

astigmatism 8 10 44 60
astigmatism, unspecified 8
unspecified astigmatism 8
astigmatism nos 8


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Disease Ontology8 DOID:11782
OMIM46 603047
ICD9CM27 367.2, 367.20
MeSH34 D001251
ICD1025 H52.2

Related Diseases for Astigmatism

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to astigmatism

Clinical Features for Astigmatism

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46OMIM
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Clinical features from OMIM:

603047

Drugs & Therapeutics for Astigmatism

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Astigmatism

Drug clinical trials:

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Search NIH Clinical Center for Astigmatism

Search CenterWatch for Astigmatism

Genetic Tests for Astigmatism

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Anatomical Context for Astigmatism

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32MalaCards
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MalaCards organs/tissues related to Astigmatism:

32
Eye, Endothelial, Testes

Animal Models for Astigmatism or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Astigmatism:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000539110.0NYX, VSX1, FGFR3, MAP3K12, FBXO7, IRX6

Publications for Astigmatism

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50PubMed
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Articles related to Astigmatism:

(show top 50)    (show all 624)
idTitleAuthorsYear
1
Ocular residual astigmatism and topographic disparity vector indexes in normal healthy eyes. (23910507)
2014
2
Prevalence of corneal astigmatism before cataract surgery in Caucasian patients. (24366768)
2013
3
Relation between uncorrected astigmatism and visual acuity in pseudophakia. (23458979)
2013
4
Results of Toric Intraocular Lenses for Post-Penetrating Keratoplasty Astigmatism. (24321143)
2013
5
Ocular residual astigmatism: Effects ofA demographic and ocular parameters inA myopicA laser in situ keratomileusis. (24333012)
2013
6
Prevalence of myopia, hyperopia, and astigmatism in non-Hispanic white and Asian children: multi-ethnic pediatric eye disease study. (23953098)
2013
7
Implantation of three-piece silicone toric additive IOLs in challenging clinical cases with high astigmatism. (23446015)
2013
8
Collagen copolymer toric phakic intraocular lens for residual myopic astigmatism after intrastromal corneal ring segment implantation and corneal collagen crosslinking in a 3-stage procedure for keratoconus. (23499066)
2013
9
Prevalence of keratoconus and subclinical keratoconus in subjects with astigmatism using pentacam derived parameters. (24349664)
2013
10
Incidence of irregular astigmatism eligible for contact lens fitting after Descemet membrane endothelial keratoplasty. (23664354)
2013
11
Collagen crosslinking and toric iris-claw phakic intraocular lens for myopic astigmatism in progressive mild to moderate keratoconus. (22261324)
2012
12
Combining refractive and topographic data in corneal refractive surgery for astigmatism: a new method based on polar value analysis and mathematical optimization. (21914142)
2012
13
Intrastromal corneal ring segment implantation for irregular astigmatism after laser in situ keratomileusis. (22520312)
2012
14
The influence of corneal wound size on surgically induced corneal astigmatism after phacoemulsification. (22656399)
2012
15
Correction of myopic astigmatism with a foldable iris-claw toric phakic intraocular lens: short-term follow-up. (22341150)
2012
16
Comparison of astigmatism correction using shorter arc length 90A^/120A^ asymmetric intacs severe keratoconus versus 150A^ single-segment intacs severe keratoconus in asymmetric keratoconus. (21926565)
2011
17
Reduction in astigmatism using propranolol as first-line therapy for periocular capillary hemangioma. (20970771)
2011
18
Methodology for third-order astigmatism compensation in off-axis spherical reflective systems. (21364730)
2011
19
Effect of uncorrected astigmatism on vision. (21333869)
2011
20
Visual acuity after laser in situ keratomileusis to correct high astigmatism in adults with meridional amblyopia. (21851919)
2011
21
Prevalence of astigmatism in Native American infants and children. (20386351)
2010
22
Astigmatism in preschool children in Taiwan. (20451858)
2010
23
Onset and progression of with-the-rule astigmatism in children with infantile nystagmus syndrome. (20019374)
2010
24
Preliminary experiences with limbal relaxing incision for treatment of astigmatism during phacoemulslfication. (21140999)
2009
25
Femtosecond-assisted astigmatic keratotomy for post-keratoplasty irregular astigmatism. (19101418)
2009
26
Excimer laser correction of moderate to high astigmatism with a non-wavefront-guided aberration-free ablation profile: Six-month results. (19781476)
2009
27
Corneal power and astigmatism in Down syndrome. (19390470)
2009
28
Blur limits for defocus, astigmatism and trefoil. (19631683)
2009
29
A comparison of Lea Symbol vs ETDRS letter distance visual acuity in a population of young children with a high prevalence of astigmatism. (19345596)
2009
30
Optical treatment reduces amblyopia in astigmatic children who receive spectacles before kindergarten. (19232733)
2009
31
The relationship between patient age and astigmatism magnitude after congenital cataract surgery. (19396781)
2009
32
Irregular astigmatism after cataract surgery resulting from inadequate clear corneal incision formation. (19034136)
2008
33
Axes of astigmatism in fellow eyes show mirror rather than direct symmetry. (18565088)
2008
34
Bungee cord-induced corneal lacerations correcting for myopic astigmatism. (17586399)
2007
35
Topography-guided ablation for treatment of patients with irregular astigmatism. (17326350)
2007
36
Site of incision and corneal astigmatism in conventional SICS versus phacoemulsification. (18025627)
2007
37
Geometric method to measure astigmatism aberration at astronomical telescopes. (17514302)
2007
38
Development of astigmatism and anisometropia in preterm children during the first 10 years of life: a population-based study. (17102009)
2006
39
Comparison of surgically induced astigmatism of temporal versus superior clear corneal incisions. (17455711)
2006
40
Topography-guided treatment of irregular astigmatism with the wavelight excimer laser. (16629063)
2006
41
Strategic planning in topography-guided ablation of irregular astigmatism after laser refractive surgery. (16128335)
2005
42
Fourier analysis of induced irregular astigmatism. Photorefractive keratectomy versus laser in situ keratomileusis in a bilateral cohort of hyperopic patients. (14522289)
2003
43
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
44
Corneal and refractive error astigmatism in Singaporean schoolchildren: a vector-based Javal's rule. (11780665)
2001
45
Regular and irregular astigmatism after superior versus temporal scleral incision cataract surgery. (11054330)
2000
46
Management of irregular astigmatism with rigid gas permeable contact lenses. (10656303)
2000
47
Accuracy and predictability of photorefractive keratectomy for astigmatism correction]. (11877233)
1998
48
Surgery in myopic astigmatism: arciform keratotomy and PKR versus PARK]. (9554138)
1997
49
Holmium:YAG laser thermokeratoplasty for hyperopia and astigmatism: an overview. (8499365)
1993
50
Fluoroperm extended wear RGP contact lenses for myopia, hyperopia, aphakia, astigmatism, and keratoconus. (2917400)
1989

Genetic Variations for Astigmatism

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Expression for genes affiliated with Astigmatism

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Astigmatism

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Pathways for genes affiliated with Astigmatism

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Compounds for genes affiliated with Astigmatism

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GO Terms for genes affiliated with Astigmatism

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16Gene Ontology
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Biological processes related to Astigmatism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mesoderm developmentGO:00749810.3MATK, IRX3
2protein autophosphorylationGO:04677710.1EIF2AK2, FGFR3, MAP3K12
3regulation of protein stabilityGO:03164710.1ASPH, FBXO7

Products for genes affiliated with Astigmatism

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  • Antibodies
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Sources for Astigmatism

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet