Aliases & Classifications for Astigmatism

MalaCards integrated aliases for Astigmatism:

Name: Astigmatism 53 12 72 28 51 41 14 69

Classifications:



External Ids:

OMIM 53 603047
Disease Ontology 12 DOID:11782
ICD10 32 H52.2 H52.20
ICD9CM 34 367.2 367.20
MeSH 41 D001251
MedGen 39 C0004106
UMLS 69 C0004106

Summaries for Astigmatism

OMIM : 53 Astigmatism (from the Greek 'a' meaning absence and 'stigma' meaning point) is a condition in which the parallel rays of light entering the eye through the refractive media are not focused on a single point. Both corneal and noncorneal factors contribute to refractive astigmatism. Corneal astigmatism is mainly the result of an aspheric anterior surface of the cornea, which can be measured readily by means of a keratometer; in a small fraction of cases (approximately 1 in 10) the effect is neutralized by the back surface. The curvature of the back surface of the cornea is not considered in most studies, because it is more difficult to measure; moreover, in the case of severe corneal astigmatism, there is evidence that both surfaces have the same configuration. Noncorneal factors are errors in the curvature of the 2 surfaces of the crystalline lens, irregularity in the refractive index of the lens, and an eccentric lens position. Since the cornea is the dominant component of the eye's refracting system, a highly astigmatic cornea is likely to result in a similarly astigmatic ocular refraction (summary by Clementi et al., 1998). (603047)

MalaCards based summary : Astigmatism is related to regular astigmatism and corneal dystrophy, meesmann, and has symptoms including blurred vision and aniseikonia. An important gene associated with Astigmatism is ANKRD11 (Ankyrin Repeat Domain 11). The drugs Dipivefrin and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotypes are skeleton and vision/eye

Disease Ontology : 12 A refractive error characterized by the optics of the eye to focus a point object into a sharp focused image on the retina, has symptom blurred vision.

Wikipedia : 72 Astigmatism is a type of refractive error in which the eye does not focus light evenly on the retina.... more...

Related Diseases for Astigmatism

Diseases related to Astigmatism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 101)
# Related Disease Score Top Affiliating Genes
1 regular astigmatism 32.7 DPT FLNA NBL1
2 corneal dystrophy, meesmann 31.5 KRT12 KRT3
3 anisometropia 30.0 ADAMTSL4 DPT GREM1
4 congenital nystagmus 30.0 FRMD7 GPR143
5 irregular astigmatism 12.2
6 refractive error 11.4
7 keratoconus 11.3
8 amblyopia 11.1
9 isolated congenital megalocornea 11.1
10 microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 10.9
11 lymphedema-distichiasis syndrome 10.9
12 ectopia lentis et pupillae 10.9
13 aland island eye disease 10.9
14 nystagmus 6, congenital, x-linked 10.9
15 nystagmus 1, congenital, x-linked 10.9
16 isolated ectopia lentis 10.9
17 keratoconus 1 10.8
18 lacrimal duct defect 10.8
19 nystagmus 2, congenital, autosomal dominant 10.8
20 nystagmus 4, congenital, autosomal dominant 10.8
21 keratoconus posticus circumscriptus 10.8
22 macrocephaly/megalencephaly syndrome, autosomal recessive 10.8
23 retinitis pigmentosa 10.8
24 nystagmus 5, congenital, x-linked 10.8
25 nystagmus 3, congenital, autosomal dominant 10.8
26 keratoconus 5 10.8
27 keratoconus 8 10.8
28 nystagmus 7, congenital, autosomal dominant 10.8
29 familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis 10.8
30 ichthyosis follicularis atrichia photophobia syndrome 10.8
31 cataract 10.6
32 myopia 10.6
33 x-linked infantile nystagmus 10.4 FRMD7 GPR143
34 corneal granular dystrophy 10.3 KRT12 KRT3
35 epithelial and subepithelial dystrophy 10.3 KRT12 KRT3
36 pathologic nystagmus 10.3 FRMD7 GPR143
37 limbal stem cell deficiency 10.3 KRT12 KRT3
38 aging 10.2
39 presbyopia 10.1
40 endotheliitis 10.1
41 corneal dystrophy, thiel-behnke type 10.1 KRT12 KRT3
42 epiblepharon 10.0
43 ocular motility disease 10.0 FRMD7 GPR143
44 corneal ectasia 9.9
45 pellucid marginal degeneration 9.9
46 blood group, i system 9.9
47 hemangioma 9.9
48 corneal degeneration 9.9
49 retinitis 9.9
50 cataract 32, multiple types 9.8

Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to Astigmatism

Symptoms & Phenotypes for Astigmatism

Clinical features from OMIM:

603047

Symptoms:

12
  • blurred vision

UMLS symptoms related to Astigmatism:


aniseikonia

MGI Mouse Phenotypes related to Astigmatism:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 skeleton MP:0005390 9.56 ANKRD11 FLNA FRMD7 GREM1 GREM2 NBL1
2 vision/eye MP:0005391 9.28 CACNA1F DPT FLNA GPR143 GREM2 KRT12

Drugs & Therapeutics for Astigmatism

Drugs for Astigmatism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 110)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dipivefrin Approved Phase 4,Phase 3 52365-63-6 3105
2
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
3
Bevacizumab Approved, Investigational Phase 4 216974-75-3
4
Fluorouracil Approved Phase 4 51-21-8 3385
5 Anesthetics Phase 4,Phase 2,Phase 3
6 Proxymetacaine Phase 4,Phase 3
7 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3,Phase 1
8 Adrenergic Agents Phase 4
9 Adrenergic Agonists Phase 4
10 Neurotransmitter Agents Phase 4
11 Angiogenesis Inhibitors Phase 4
12 Angiogenesis Modulating Agents Phase 4
13 Antimetabolites Phase 4
14 Antimetabolites, Antineoplastic Phase 4
15 Immunosuppressive Agents Phase 4
16
Lidocaine Approved, Vet_approved Phase 2, Phase 3 137-58-6 3676
17
Menthol Approved Phase 3 2216-51-5 16666
18
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
19
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3, Phase 1 59-30-3 6037
20
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3, Phase 1 83-88-5 493570
21 tannic acid Approved, Nutraceutical Phase 3
22 Anesthetics, Local Phase 2, Phase 3
23 Anti-Arrhythmia Agents Phase 2, Phase 3
24 Central Nervous System Depressants Phase 2, Phase 3
25 Dermatologic Agents Phase 2, Phase 3, Phase 1
26 Dextrans Phase 2, Phase 3, Phase 1
27 Diuretics, Potassium Sparing Phase 2, Phase 3
28
Flavin Mononucleotide Phase 2, Phase 3 146-17-8 643976
29 Micronutrients Phase 2, Phase 3, Phase 1
30 Peripheral Nervous System Agents Phase 2, Phase 3
31 Photosensitizing Agents Phase 2, Phase 3, Phase 1
32 Sodium Channel Blockers Phase 2, Phase 3
33 Trace Elements Phase 2, Phase 3, Phase 1
34 Vitamin B Complex Phase 2, Phase 3, Phase 1
35 Vitamins Phase 2, Phase 3, Phase 1
36 Mitomycins Phase 3,Phase 1
37 Ophthalmic Solutions Phase 3,Phase 1,Phase 2
38 Polymethyl Methacrylate Phase 3
39 Protective Agents Phase 3
40 Vasodilator Agents Phase 3
41 Anticoagulants Phase 3,Phase 1,Phase 2
42 Blood Substitutes Phase 3,Phase 1,Phase 2
43 Plasma Substitutes Phase 3,Phase 1,Phase 2
44 Folate Nutraceutical Phase 2, Phase 3, Phase 1
45 Vitamin B2 Nutraceutical Phase 2, Phase 3, Phase 1
46 Vitamin B9 Nutraceutical Phase 2, Phase 3, Phase 1
47 Anti-Bacterial Agents Phase 2,Phase 1
48 Mydriatics Phase 2,Phase 1,Early Phase 1
49 Anti-Infective Agents Phase 2
50 Alkylating Agents Phase 1

Interventional clinical trials:

(show top 50) (show all 301)

# Name Status NCT ID Phase Drugs
1 Effect of Posterior Corneal Toricity on Refractive Outcome of Pseudophakia Unknown status NCT01554761 Phase 4
2 Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism Unknown status NCT01628146 Phase 4
3 Clinical Evaluation of Toric Intraocular Lens Made by Aurolab Unknown status NCT01396616 Phase 4
4 A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular Lenses Unknown status NCT02264457 Phase 4
5 Multi Laser Platform Comparison Study for LASIK Unknown status NCT00770094 Phase 4
6 Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism Completed NCT01763151 Phase 4
7 Use of Toric Intraocular Lens to Neutralize Keratometric Astigmatism Completed NCT00925886 Phase 4
8 Intrastromal Corneal Ring for High Astigmatism on Postkeratoplasty Completed NCT01018797 Phase 4
9 Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism Completed NCT01965288 Phase 4
10 Prospective Evaluation of the Effectiveness of the Femtosecond Laser-assisted Refractive Astigmatic Keratotomy. Completed NCT01885780 Phase 4
11 Safety and Effectiveness of the Akreos Toric Intraocular Lens. Completed NCT00825513 Phase 4
12 Clinical Performance of Habitual Hydrogel vs. Silicone Hydrogel Toric Contact Lenses Completed NCT02142361 Phase 4
13 Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK Completed NCT00821236 Phase 4
14 Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial Completed NCT01279031 Phase 4
15 AcrySof Toric Clinical Results Completed NCT01214863 Phase 4
16 Low Cylinder Toric Completed NCT00732030 Phase 4
17 An Evaluation of Outcomes Following Wavefront Optimized or Wavefront Guided Lasik Procedure in Low to Moderate Myopic Patients Completed NCT01173198 Phase 4
18 Visual Outcomes After Implantation of a New Multifocal Intraocular Lens Completed NCT01505816 Phase 4
19 Daily Wear Corneal Infiltrative Event Study Completed NCT00937105 Phase 4
20 Co-Axial Micro-Incision Versus Co-Axial Small Incision Cataract Surgery Using the Stellaris Enhancement System Completed NCT01261975 Phase 4
21 High Resolution Wavefront-guided vs. Wavefront Optimized LASIK Recruiting NCT02565537 Phase 4
22 A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery Recruiting NCT03067077 Phase 4
23 LASIK Using the Alcon Allegretto Wavefront-Guided Excimer Laser vs AMO Visx Wavefront-Guided Excimer Laser Active, not recruiting NCT01454843 Phase 4
24 Wavefront-guided PRK vs Wavefront-optimized PRK Active, not recruiting NCT02091934 Phase 4
25 Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia Active, not recruiting NCT01140594 Phase 4
26 Strategies for Management of Recurrent Pterygium Active, not recruiting NCT02530801 Phase 4 Bevacizumab;5 fluorouracil
27 Topography-guided LASIK Surgery Not yet recruiting NCT03292419 Phase 4
28 Recommendations for Monitoring Clinical Experience Following Implantation of the AcrySof® Toric Withdrawn NCT00761488 Phase 4
29 SUPRACOR for Myopia and Myopic Astigmatism Unknown status NCT01404884 Phase 3
30 Evaluation of the BunnyLens TR Intraocular Lens Unknown status NCT01659801 Phase 3
31 Intrastromal Correction of Ametropia by a Femtosecond Laser Unknown status NCT00928122 Phase 3
32 Comparison of Penetrating Keratoplasty and Deep Lamellar Keratoplasty With the Big Bubble Technique for Keratoconus Unknown status NCT00371202 Phase 3
33 Treatment of Keratoconus Using Collagen Cross-Linking Unknown status NCT00841386 Phase 2, Phase 3 Riboflavin-5-phosphate;Sham cross-linking
34 Evaluating the Safety and Efficacy of the KXL System for Corneal Collagen Cross-Linking in Eyes Having Keratoconus Unknown status NCT02638376 Phase 3
35 Comparison of Cross-cylinder and Conventional Photorefractive Keratectomy(PRK) in Correcting Medium-high Astigmatism Completed NCT00663923 Phase 3
36 The Berkeley Orthokeratology Study Completed NCT00000123 Phase 3
37 Multicenter Evaluation of Safety and Effectiveness of Presbyopic LASIK for Hyperopes Completed NCT00910403 Phase 3
38 A Prospective Study of Femtosecond Laser Intracorneal Lensectomi Completed NCT01673503 Phase 3
39 Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria Completed NCT00785135 Phase 3
40 Economic Evaluation of Femtosecond Laser Assisted Cataract Surgery Completed NCT01982006 Phase 3
41 Collagen Crosslinking for Keratoconus - a Randomized Controlled Clinical Trial Recruiting NCT01604135 Phase 3
42 Safety and Effectiveness of Corneal Crosslinking (CXL): Keratoconus and Post-Refractive Ectasia Recruiting NCT03080077 Phase 3 Ricrolin+;Epi-Off
43 Corneal Cross Linking and Topography Guided Excimer Laser Treatment Terminated NCT01682993 Phase 3
44 Myoring Versus Keraring Implantation for Keratoconus Unknown status NCT01869517 Phase 2
45 Safety and Effectiveness of Arcuate Incisions Performed With the iFS Femtosecond Laser System Completed NCT01348854 Phase 2
46 Wavefront Analyzes and Visual Performance of Three Multifocal Intra-ocular Lenses Completed NCT00876707 Phase 1, Phase 2
47 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
48 Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions Completed NCT01024855 Phase 1, Phase 2
49 Eye Muscle Surgery to Treat Congenital Nystagmus Completed NCT00001866 Phase 2
50 Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism Terminated NCT01893359 Phase 1, Phase 2 riboflavin ophthalmic solution, 0% dextran

Search NIH Clinical Center for Astigmatism

Cochrane evidence based reviews: astigmatism

Genetic Tests for Astigmatism

Genetic tests related to Astigmatism:

# Genetic test Affiliating Genes
1 Astigmatism 28

Anatomical Context for Astigmatism

MalaCards organs/tissues related to Astigmatism:

38
Eye, Retina, Endothelial, Testes

Publications for Astigmatism

Articles related to Astigmatism:

(show top 50) (show all 784)
# Title Authors Year
1
Visual Outcomes and Aberrometric Changes With Topography-Guided Photorefractive Keratectomy Treatment of Irregular Astigmatism After Penetrating Keratoplasty. ( 29215394 )
2018
2
Non-Orthogonal Corneal Astigmatism among Normal and Keratoconic Brazilian and Chinese populations. ( 29393696 )
2018
3
Importance of Posterior Corneal Astigmatism in Eyes with Keratoconus. ( 29403581 )
2018
4
Development of a real-time wave field reconstruction TEM system (II): correction of coma aberration and 3-fold astigmatism, and real-time correction of 2-fold astigmatism. ( 29315401 )
2018
5
Age-related changes in with-the-rule and oblique corneal astigmatism. ( 29369508 )
2018
6
Surgically induced astigmatism after phacoemulsification by temporal clear corneal and superior clear corneal approach: a comparison. ( 29379266 )
2018
7
Role of Hemidivisional Corneal Topographic Astigmatisms (CorTs) in the Regularization and Reduction of Irregular Astigmatism. ( 29135603 )
2018
8
Unusual Internal Astigmatism Due to Severe Capsule Contraction Syndrome. ( 29315444 )
2018
9
Characteristics of Posterior Corneal Astigmatism in Different Stages of Keratoconus. ( 29403582 )
2018
10
Comparability and repeatability of different methods of corneal astigmatism assessment. ( 29339918 )
2018
11
A genome-wide association study of corneal astigmatism: The CREAM Consortium. ( 29422769 )
2018
12
Prevalence of corneal astigmatism before cataract surgery in Western Indian Population. ( 29386726 )
2018
13
Changes in shape and astigmatism of total, anterior, and posterior cornea after long versus short clear corneal incision cataract surgery. ( 29395715 )
2018
14
Defocus and magnification dependent variation of TEM image astigmatism. ( 29321616 )
2018
15
Comparison of astigmatism prediction error taken with the Pentacam measurements, Baylor nomogram, and Barrett formula for toric intraocular lens implantation. ( 28836956 )
2017
16
Analysis of the Ocular Refractive State in Fighting Bulls: Astigmatism Prevalence. ( 29230414 )
2017
17
Validity of autorefractor based screening method for irregular astigmatism compared to the corneal topography- a cross sectional study. ( 28944202 )
2017
18
Stepwise Guided Photorefractive Keratectomy in Treatment of Irregular Astigmatism After Penetrating Keratoplasty and Deep Anterior Lamellar Keratoplasty. ( 28914632 )
2017
19
Association between mode of delivery and astigmatism in preschool children. ( 28887859 )
2017
20
Polar Value Analysis of Low to Moderate Astigmatism with Wavefront-Guided Sub-Bowman Keratomileusis. ( 28831306 )
2017
21
Comparison between toric and spherical phakic intraocular lenses combined with astigmatic keratotomy for high myopic astigmatism. ( 28828390 )
2017
22
Refractive Outcomes of Posterior Chamber Phakic Intraocular Lens Implantation for Correction of Myopia and Myopic Astigmatism. ( 28790537 )
2017
23
Comparison of surgically induced astigmatism following different glaucoma operations. ( 29238159 )
2017
24
Aspheric versus wavefront-guided aspheric photorefractive keratectomy in eyes with significant astigmatism. ( 29335097 )
2017
25
Repair of Irregularly Irregular Astigmatism by Transepithelial Phototherapeutic Keratectomy. ( 28991341 )
2017
26
Implantation of a Multifocal Toric Intraocular Lens after Radial Keratotomy and Cross-Linking with Hyperopia and Astigmatism Residues: A Case Report. ( 28924444 )
2017
27
Correction of High Astigmatism after Penetrating Keratoplasty with Toric Multifocal Intraocular Lens Implantation. ( 28868034 )
2017
28
Scheimpflug topographical changes after Femtosecond LASIK for mixed astigmatism - theoretical aspects and case study. ( 29450375 )
2017
29
Post-keratoplasty astigmatism management by relaxing incisions: a systematic review. ( 29238735 )
2017
30
Refractive Outcomes of 20 Eyes Undergoing ICL Implantation for Correction of Hyperopic Astigmatism. ( 28880335 )
2017
31
Neck/shoulder discomfort due to visually demanding experimental near work is influenced by previous neck pain, task duration, astigmatism, internal eye discomfort and accommodation. ( 28832612 )
2017
32
Anisometropia of spherical equivalent and astigmatism among myopes: a 23-year follow-up study of prevalence and changes from childhood to adulthood. ( 28481050 )
2017
33
Changes in Astigmatism, Densitometry, and Aberrations After SMILE for Low to High Myopic Astigmatism: A 12-Month Prospective Study. ( 28068441 )
2017
34
Photorefractive keratectomy in the management of postradial keratotomy hyperopia and astigmatism. ( 28919909 )
2017
35
Early visual outcomes and optical quality after femtosecond laser small-incision lenticule extraction for myopia and myopic astigmatism correction of over -10 dioptres. ( 29251814 )
2017
36
Correction of hyperopia with astigmatism following radial keratotomy with daily disposable plus spherical contact lens: a case report. ( 28856508 )
2017
37
Comparison of Methodologies Using Estimated or Measured Values of Total Corneal Astigmatism for Toric Intraocular Lens Power Calculation. ( 29227506 )
2017
38
Correction of irregular and induced regular corneal astigmatism with toric IOL after posterior segment surgery: a case series. ( 28086913 )
2017
39
Consistency analysis of surgically induced astigmatism. ( 28917416 )
2017
40
Axis-free correction of astigmatism using bifocal soft contact lenses. ( 28935527 )
2017
41
Intrastromal Corneal Ring Segments for Astigmatism Correction after Deep Anterior Lamellar Keratoplasty. ( 28951784 )
2017
42
Note: Measurement of synchrotron radiation phase-space beam properties to verify astigmatism compensation in Fresnel zone plate focusing optics. ( 28863654 )
2017
43
Clinical outcomes of laser inA situ keratomileusis with an aberration-neutral profile centered on the corneal vertex comparing vector planning with manifest refraction planning for the treatment of myopic astigmatism. ( 29335094 )
2017
44
Comparison of refractive and keratometric astigmatism after microincision cataractA surgery. ( 28917405 )
2017
45
Refractive, corneal and ocular residual astigmatism: distribution in a German population and age-dependency - the Gutenberg health study. ( 28823075 )
2017
46
Effect of iris registration on outcomes of FEMTOLASIK for myopia and myopic astigmatism. ( 28875250 )
2017
47
Combination of Toric and multifocal intraocular lens implantation in bilateral cataract patients with unilateral astigmatism. ( 28003977 )
2016
48
Effectiveness of Toric Orthokeratology in the Treatment of Patients with Combined Myopia and Astigmatism. ( 27980362 )
2016
49
Treatment of mixed astigmatism: early clinical outcomes withWaveLight and Technolas excimer lasers. ( 27513239 )
2016
50
Evaluation of the diagnostic ability of vector parameters characterizing the corneal astigmatism and regularity in clinical and subclinical keratoconus. ( 27931882 )
2016

Variations for Astigmatism

ClinVar genetic disease variations for Astigmatism:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 ANKRD11 NM_013275.5(ANKRD11): c.5317G> T (p.Glu1773Ter) single nucleotide variant Pathogenic rs1114167291 GRCh37 Chromosome 16, 89347633: 89347633
2 GRIN2B NM_000834.4(GRIN2B): c.2002G> A (p.Asp668Asn) single nucleotide variant Pathogenic/Likely pathogenic rs876661151 GRCh38 Chromosome 12, 13608611: 13608611

Expression for Astigmatism

Search GEO for disease gene expression data for Astigmatism.

Pathways for Astigmatism

GO Terms for Astigmatism

Cellular components related to Astigmatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 8.92 CACNA1F FLNA FRMD7 NRXN1

Biological processes related to Astigmatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.62 CACNA1F GPR143 KRT12 VAX2
2 negative regulation of BMP signaling pathway GO:0030514 9.43 GREM1 GREM2 NBL1
3 negative regulation of monocyte chemotaxis GO:0090027 9.16 GREM1 NBL1
4 sequestering of BMP from receptor via BMP binding GO:0038098 8.96 GREM2 NBL1
5 determination of dorsal identity GO:0048263 8.8 GREM1 GREM2 NBL1

Molecular functions related to Astigmatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.55 FLNA GREM1 GREM2 NBL1 PDGFRA
2 morphogen activity GO:0016015 8.96 GREM1 NBL1
3 BMP binding GO:0036122 8.8 GREM1 GREM2 NBL1

Sources for Astigmatism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....