MCID: AST006
MIFTS: 38

Astigmatism malady

Eye category

Summaries for Astigmatism

Sources:
64Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:64 An optical system with astigmatism is one where rays that propagate in two perpendicular planes have... more...

MalaCards: Astigmatism, also known as astigmatism, unspecified, is related to irregular astigmatism and hyperopia. An important gene associated with Astigmatism is VSX1 (visual system homeobox 1). Affiliated tissues include endothelial, and related mouse phenotype vision/eye.

Description from OMIM:47 603047

Aliases & Classifications for Astigmatism

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 47OMIM, 57SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye


Aliases & Descriptions:

astigmatism 8 10 45 61
astigmatism, unspecified 8
unspecified astigmatism 8
astigmatism nos 8


External Ids:

Disease Ontology8 DOID:11782
OMIM47 603047
ICD9CM27 367.2, 367.20
MeSH35 D001251
ICD1025 H52.2

Related Diseases for Astigmatism

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Astigmatism via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1irregular astigmatism31.2FBXO7, CHST6, VSX1, NYX
2hyperopia31.0FRMD7, MATK, CACNA1F
3regular astigmatism30.6VSX1, ASPH
4aland island eye disease29.8NYX, CACNA1F
5anisometropia10.4
6amblyopia10.3
7presbyopia10.3
8epiblepharon10.3
9corneal ectasia10.2
10pellucid marginal degeneration10.1
11bullous keratopathy10.0
12congenital nystagmus10.0
13lymphedema-distichiasis syndrome10.0
14keratoconus 110.0
15ocular albinism10.0FRMD7
16keratoconus10.0VSX1, FBXO7
17x-linked congenital stationary night blindness10.0CACNA1F, NYX
18oguchi disease 110.0NYX, CACNA1F
19hereditary night blindness10.0NYX, CACNA1F
20brugada syndrome10.0KCNE3
21corneal dystrophy10.0FBXO7, CHST6, VSX1
22congenital stationary night blindness10.0NYX, CACNA1F
23myopia 610.0NYX, EIF2AK2, DAND5, MATK, CACNA1F
24corneal edema10.0VSX1, FBXO7
25corneal disease9.9
26neurofibromatosis9.9
27asthenopia9.9
28aniseikonia9.9
29cystoid macular edema9.9
30juvenile xanthogranuloma9.9
31aniridia9.9
32coloboma9.9
33pseudopterygium9.9
34exudative vitreoretinopathy9.9
35oculocutaneous albinism9.9
36accommodative esotropia9.9
37blepharospasm9.9
38scotoma9.9
39primary open angle glaucoma9.9
40pemphigus9.9
41n syndrome9.9
42recurrent corneal erosion9.9
43strabismus9.9
44synostosis9.9
45short syndrome9.9
46stickler syndrome type 19.9
47axial spondylometaphyseal dysplasia9.9
48cataract-glaucoma9.9
49caudal appendage deafness9.9
5016q24.3 microdeletion syndrome9.9

Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to astigmatism

Clinical Features for Astigmatism

Sources:
47OMIM
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Clinical features from OMIM:

603047

Drugs & Therapeutics for Astigmatism

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Astigmatism

Drug clinical trials:

Search ClinicalTrials for Astigmatism

Search NIH Clinical Center for Astigmatism

Search CenterWatch for Astigmatism

Genetic Tests for Astigmatism

Anatomical Context for Astigmatism

Sources:
33MalaCards
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MalaCards organs/tissues related to Astigmatism:

33
Endothelial

Animal Models for Astigmatism or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Astigmatism:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000539110.0NYX, VSX1, FGFR3, MAP3K12, FBXO7, IRX6

Publications for Astigmatism

Sources:
51PubMed
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Articles related to Astigmatism:

(show top 50)    (show all 606)
idTitleAuthorsYear
1
Correcting lenticular astigmatism by reinstating the correct neuromuscular message. (23639283)
2013
2
Developmental changes in anterior corneal astigmatism in Tohono O'odham Native American infants and children. (23510314)
2013
3
Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser. (23158680)
2013
4
Relation between uncorrected astigmatism and visual acuity in pseudophakia. (23458979)
2013
5
Results of Toric Intraocular Lenses for Post-Penetrating Keratoplasty Astigmatism. (24321143)
2013
6
Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. (23761726)
2013
7
Femtosecond laser-assisted intrastromal corneal ring segment implantation for high astigmatism correction after penetrating keratoplasty. (24011932)
2013
8
Effects of pterygium surgery on front and back corneal astigmatism. (23036543)
2012
9
Perceptual adaptation to the correction of natural astigmatism. (23050021)
2012
10
Wavefront-guided versus cross-cylinder photorefractive keratectomy in moderate-to-high astigmatism: a cohort of two consecutive clinical trials. (22331978)
2012
11
Intrastromal corneal ring segment implantation for irregular astigmatism after laser in situ keratomileusis. (22520312)
2012
12
High-cylinder acrylic toric intraocular lenses: a case series of eyes with cataracts and large amounts of corneal astigmatism. (22335205)
2012
13
Meridional lenticular astigmatism associated with bilateral concurrent uveal metastases in renal cell carcinoma. (23152663)
2012
14
Axial nanodisplacement measurement based on astigmatism effect of crossed cylindrical lenses. (22614415)
2012
15
Visual acuity improvements after implantation of toric intraocular lenses in cataract patients with astigmatism: a systematic review. (22894651)
2012
16
Numerical analysis of astigmatism correction in gradient refractive index lens based optical coherence tomography catheters. (22858968)
2012
17
Visual performance in cataract patients with low levels of postoperative astigmatism: full correction versus spherical equivalent correction. (22399846)
2012
18
Low-cost adaptive astigmatism compensator for improvement of eye fundus camera. (22048352)
2011
19
Minimizing surgically induced astigmatism at the time of cataract surgery using a square posterior limbal incision. (22132310)
2011
20
Differences in corneal astigmatism between partial coherence interferometry biometry and automated keratometry and relation to topographic pattern. (21855766)
2011
21
Astigmatism-corrected Czerny-Turner imaging spectrometer for broadband spectral simultaneity. (21460898)
2011
22
Corneal astigmatism in unilateral Fuchs heterochromic iridocyclitis. (21595529)
2011
23
Astigmatism in preschool children in Taiwan. (20451858)
2010
24
The effect of epiblepharon surgery on visual acuity and with-the-rule astigmatism in children. (21165229)
2010
25
The AcrySof Toric intraocular lens in subjects with cataracts and corneal astigmatism: a randomized, subject-masked, parallel-group, 1-year study. (20846724)
2010
26
Arcuate keratotomy: an option for astigmatism correction after laser in situ keratomileusis. (19730093)
2009
27
Mild myopic astigmatism corrected by accidental flap complication: a case report. (20404996)
2009
28
LASIK for hyperopic astigmatism and presbyopia using micro-monovision with the Carl Zeiss Meditec MEL80 platform. (19244952)
2009
29
Femtosecond-assisted astigmatic keratotomy for post-keratoplasty irregular astigmatism. (19101418)
2009
30
Excimer laser correction of moderate to high astigmatism with a non-wavefront-guided aberration-free ablation profile: Six-month results. (19781476)
2009
31
Corneal topography six years after photorefractive keratectomy for myopia and myopic astigmatism. (19507798)
2009
32
Independent control of beam astigmatism and ellipticity using a SLM for fs-laser waveguide writing. (19997320)
2009
33
Management of irregular astigmatism following rotationally disoriented free cap after LASIK. (18500089)
2008
34
Induced corneal astigmatism by palpebral spring for the treatment of lagophthalmos. (18650674)
2008
35
Visual outcomes of wavefront-guided laser in situ keratomileusis in eyes with moderate or high myopia and compound myopic astigmatism. (18165076)
2008
36
Wavefront-optimized versus wavefront-guided LASIK for myopic astigmatism with the ALLEGRETTO WAVE: three-month results of a prospective FDA trial. (18500097)
2008
37
Astigmatism management in cataract surgery with the AcrySof toric intraocular lens. (18721707)
2008
38
Customized photoastigmatic refractive keratectomy using combined topographic and refractive data for myopia and astigmatism in eyes with forme fruste and mild keratoconus. (17397730)
2007
39
Geometric customization of optical and transition zone parameters for treatment of compound myopic astigmatism with the NIDEK EC-5000 excimer laser. (18041247)
2007
40
Phototherapeutic keratectomy for epithelial irregular astigmatism: an emphasis on map-dot-fingerprint degeneration. (17269244)
2007
41
Long-term results of photorefractive keratectomy for myopia and myopic astigmatism. (18235910)
2007
42
Prevalence and associations of anisometropia and aniso-astigmatism in a population based sample of 6 year old children. (16622090)
2006
43
Intraocular lens calculations in patients with corneal scarring and irregular astigmatism. (12900244)
2003
44
Topographically guided ablations for the correction of irregular astigmatism after corneal surgery. (12881654)
2003
45
Photorefractive keratectomy using the meditec MEL 70 G-scan laser for hyperopia and hyperopic astigmatism. (12361155)
2002
46
Laser in situ keratomileusis for correction of hyperopia and hyperopic astigmatism with the Technolas 117C. (12160152)
2002
47
Management of irregular astigmatism with rigid gas permeable contact lenses. (10656303)
2000
48
The use of the SoftPerm lens for the correction of irregular astigmatism. (1499124)
1992
49
Prevalences of astigmatism and anisometropia in adult danes. With reference to presbyopes' possible use of supermarket standard glasses. (6464688)
1984
50
Irregular astigmatism following episcleral buckling procedure with the use of silicone rubber sponges. (4759429)
1973

Genetic Variations for Astigmatism

Expression for genes affiliated with Astigmatism

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Astigmatism

Search GEO for disease gene expression data for Astigmatism.

Pathways for genes affiliated with Astigmatism

Compounds for genes affiliated with Astigmatism

GO Terms for genes affiliated with Astigmatism

Sources:
16Gene Ontology
See all sources

Biological processes related to Astigmatism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mesoderm developmentGO:00749810.3MATK, IRX3
2protein autophosphorylationGO:04677710.1EIF2AK2, FGFR3, MAP3K12
3regulation of protein stabilityGO:03164710.1ASPH, FBXO7

Products for genes affiliated with Astigmatism

  • Antibodies
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  • Lysates
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Sources for Astigmatism

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet