MCID: AST006
MIFTS: 42

Astigmatism malady

Eye diseases category
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Summaries for Astigmatism

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Sources:
65Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:65 An optical system with astigmatism is one where rays that propagate in two perpendicular planes have... more...

MalaCards: Astigmatism, also known as astigmatism, unspecified, is related to irregular astigmatism and keratoconus. An important gene associated with Astigmatism is VSX1 (visual system homeobox 1). The compound sulfate have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and testes, and related mouse phenotypes are digestive/alimentary and vision/eye.

Description from OMIM:47 603047

Aliases & Classifications for Astigmatism

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 47OMIM, 27ICD9CM, 35MeSH, 58SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

astigmatism 8 10 45 62
astigmatism, unspecified 8
unspecified astigmatism 8
astigmatism nos 8


External Ids:

Disease Ontology8 DOID:11782
OMIM47 603047
ICD9CM27 367.2, 367.20
MeSH35 D001251
ICD1025 H52.2

Related Diseases for Astigmatism

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to astigmatism

Symptoms for Astigmatism

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47OMIM
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Clinical features from OMIM:

603047

Drugs & Therapeutics for Astigmatism

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Astigmatism

Search NIH Clinical Center for Astigmatism

Genetic Tests for Astigmatism

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Anatomical Context for Astigmatism

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33MalaCards
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MalaCards organs/tissues related to Astigmatism:

33
Eye, Endothelial, Testes

Animal Models for Astigmatism or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Astigmatism:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5FGFR3, DNAH5, ASPH
2MP:00053918.4FGFR3, VSX1, NYX, FBXO7
3MP:00053828.2ASPH, DNAH5, FGFR3

Publications for Astigmatism

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52PubMed
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Articles related to Astigmatism:

(show top 50)    (show all 618)
idTitleAuthorsYear
1
Time course of induced astigmatism after canaloplasty. (24370811)
2014
2
Correcting lenticular astigmatism by reinstating the correct neuromuscular message. (23639283)
2013
3
Prevalence of corneal astigmatism before cataract surgery in Caucasian patients. (24366768)
2013
4
Predicting ocular residual astigmatism using corneal and refractive parameters: a myopic eye study. (23621376)
2013
5
Developmental changes in anterior corneal astigmatism in Tohono O'odham Native American infants and children. (23510314)
2013
6
Effect of steepest-meridian clear corneal incision for reducing preexisting corneal astigmatism using a meridian-marking method or surgeon's intuition. (24157251)
2013
7
Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for moderate to high myopic astigmatism. (23409187)
2013
8
Wearing time as a measure of success of scleral lenses for patients with irregular astigmatism. (24145901)
2013
9
Effects of induced astigmatism on foot placement strategies when stepping onto a raised surface. (23717414)
2013
10
Astigmatism and its role in emmetropization. (23644224)
2013
11
Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser. (23158680)
2013
12
Modern management of astigmatism. (23221886)
2013
13
Heritability of refractive astigmatism: a population-based twin study among 63- to 75-year-old female twins. (23950154)
2013
14
Prevalence of corneal astigmatism before cataract surgery in Chinese patients. (23141077)
2013
15
Astigmatism in patients with idiopathic congenital nystagmus. (23456100)
2013
16
Effects of pterygium surgery on front and back corneal astigmatism. (23036543)
2012
17
Perceptual adaptation to the correction of natural astigmatism. (23050021)
2012
18
Corneal astigmatism after micro-incision cataract operation. (22486146)
2012
19
Iris-fixated toric phakic intraocular lens for myopic astigmatism. (22613689)
2012
20
Contribution of posterior corneal astigmatism to total corneal astigmatism. (23069271)
2012
21
Time course of refractive and corneal astigmatism after laser in situ keratomileusis for moderate to high astigmatism. (22814047)
2012
22
Can opposite clear corneal incisions have a role with post-laser in situ keratomileusis astigmatism? (22623863)
2012
23
Postoperative astigmatism in the second eye undergoing cataract surgery. (21402984)
2011
24
Comparison of astigmatism correction using shorter arc length 90A^/120A^ asymmetric intacs severe keratoconus versus 150A^ single-segment intacs severe keratoconus in asymmetric keratoconus. (21926565)
2011
25
Prevalence of astigmatism in a paediatric population with malocclusions. (21668278)
2011
26
Correction of astigmatism during cataract surgery: toric intraocular lens compared to peripheral corneal relaxing incisions. (20873707)
2011
27
Keratometry measurements, corneal astigmatism and irregularity in a normal population: the Tehran Eye Study. (21205266)
2010
28
Intraocular omni-focal lens with increased tolerance to decentration and astigmatism. (20199017)
2010
29
Prevalence of astigmatism in Native American infants and children. (20386351)
2010
30
Collagen copolymer toric posterior chamber phakic intraocular lenses to correct high myopic astigmatism. (20656159)
2010
31
Toric intraocular lens versus opposite clear corneal incisions to correct astigmatism in eyes having cataract surgery. (19781484)
2009
32
Postoperative astigmatism and axis stability after implantation of the STAAR Toric Implantable Collamer Lens. (19507791)
2009
33
Femtosecond laser arcuate keratotomy for the correction of high astigmatism after keratoplasty. (19395035)
2009
34
Changes in astigmatism after surgery for epiblepharon in highly astigmatic children: a controlled study. (18835734)
2008
35
Management of irregular astigmatism following rotationally disoriented free cap after LASIK. (18500089)
2008
36
Astigmatism terminology. (18721693)
2008
37
Astigmatism, its measurement, and fundamental optical properties. (17992838)
2007
38
Limbal relaxing incisions to correct corneal astigmatism during phacoemulsification. (17523513)
2007
39
Active cyclotorsion error correction during LASIK for myopia and myopic astigmatism with the NIDEK EC-5000 CX III laser. (18047004)
2007
40
Corneal astigmatism with upper eyelid gold weight implantation using the combined high pretarsal and levator fixation technique. (17881989)
2007
41
Bungee cord-induced corneal lacerations correcting for myopic astigmatism. (17586399)
2007
42
Strategic planning in topography-guided ablation of irregular astigmatism after laser refractive surgery. (16128335)
2005
43
Laser in situ keratomileusis for hyperopia and hyperopic and mixed astigmatism with LADARVision using 7 to 10-mm ablation diameters. (14518743)
2003
44
Modified astigmatism dial diagram for locating eccentric fixation in patients with central scotoma. (12749291)
2003
45
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
46
Refractive error changes in mixed astigmatism. (10768025)
1999
47
Epiblepharon of the lower eyelid: classification and association with astigmatism. (9510654)
1997
48
Disciform keratitis causing severe irregular astigmatism. (8743008)
1996
49
Escalation of keratospeak: regular and irregular astigmatism. (2248932)
1990
50
Visual acuity, refractive error, and astigmatism following corneal transplantation for pseudophakic bullous keratopathy. (3909036)
1985

Variations for Astigmatism

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Expression for genes affiliated with Astigmatism

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Astigmatism

Search GEO for disease gene expression data for Astigmatism.

Pathways for genes affiliated with Astigmatism

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Compounds for genes affiliated with Astigmatism

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45Novoseek, 24HMDB
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Compounds related to Astigmatism according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1sulfate45 2410.4FGFR3, CHST6

GO Terms for genes affiliated with Astigmatism

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16Gene Ontology
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Biological processes related to Astigmatism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1visual perceptionGO:0076019.7VSX1, NYX
2response to stimulusGO:0508969.4VSX1, NYX
3regulation of protein stabilityGO:0316479.0ASPH, FBXO7

Products for genes affiliated with Astigmatism

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Astigmatism

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet