MCID: AST006
MIFTS: 41

Astigmatism malady

Eye diseases category

Summaries for Astigmatism

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63Wikipedia, 46OMIM, 32MalaCards
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Wikipedia:63 An optical system with astigmatism is one where rays that propagate in two perpendicular planes have... more...

MalaCards: Astigmatism, also known as astigmatism, unspecified, is related to irregular astigmatism and keratoconus. An important gene associated with Astigmatism is VSX1 (visual system homeobox 1). Affiliated tissues include eye, endothelial and testes, and related mouse phenotype vision/eye.

Description from OMIM:46 603047

Aliases & Classifications for Astigmatism

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 46OMIM, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

astigmatism 8 10 44 60
astigmatism, unspecified 8
unspecified astigmatism 8
astigmatism nos 8


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Disease Ontology8 DOID:11782
OMIM46 603047
ICD9CM27 367.2, 367.20
MeSH34 D001251
ICD1025 H52.2

Related Diseases for Astigmatism

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Astigmatism:



Diseases related to astigmatism

Clinical Features for Astigmatism

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46OMIM
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Clinical features from OMIM:

603047

Drugs & Therapeutics for Astigmatism

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Astigmatism

Drug clinical trials:

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Search NIH Clinical Center for Astigmatism

Search CenterWatch for Astigmatism

Genetic Tests for Astigmatism

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Anatomical Context for Astigmatism

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32MalaCards
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MalaCards organs/tissues related to Astigmatism:

32
Eye, Endothelial, Testes

Animal Models for Astigmatism or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Astigmatism:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000539110.0NYX, VSX1, FGFR3, MAP3K12, FBXO7, IRX6

Publications for Astigmatism

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50PubMed
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Articles related to Astigmatism:

(show top 50)    (show all 624)
idTitleAuthorsYear
1
Astigmatism in patients with idiopathic congenital nystagmus. (23456100)
2013
2
Surgically Induced Astigmatism Following Glaucoma Surgery in Egyptian Patients. (24326967)
2013
3
Artisan iris-fixated toric phakic intraocular lens for the correction of high astigmatism after deep anterior lamellar keratoplasty. (24109249)
2013
4
Influence of corneal biomechanical properties on surgically induced astigmatism in cataract surgery. (23756347)
2013
5
Objective evaluation of refractive data and astigmatism: quantification and analysis. (24336294)
2013
6
Supplementary effect of static cyclotorsion compensation with dynamic cyclotorsion compensation on the refractive and visual outcomes of laser in situ keratomileusis for myopic astigmatism. (23535381)
2013
7
Cataract surgery with toric intraocular lens for correction of high corneal astigmatism. (23931461)
2013
8
Corneal astigmatism after micro-incision cataract operation. (22486146)
2012
9
Astigmatism correction: Laser in situ keratomileusis versus posterior chamber collagen copolymer toric phakic intraocular lens implantation. (22321354)
2012
10
Toric intraocular lens implantation for astigmatism correction in cataract surgery. (23115959)
2012
11
Lenticular meridional astigmatism secondary to iris mesectodermal leiomyoma. (22153095)
2012
12
Visual acuity improvements after implantation of toric intraocular lenses in cataract patients with astigmatism: a systematic review. (22894651)
2012
13
Topography-guided hyperopic and hyperopic astigmatism femtosecond laser-assisted LASIK: long-term experience with the 400 Hz eye-Q excimer platform. (22791969)
2012
14
Residual astigmatism after toric intraocular lens implantation. (22440449)
2012
15
Astigmatism following small incision cataract extraction through superotemporal incision. (22678873)
2012
16
Retrospective analysis of changes in the anterior corneal surface after Q value guided LASIK and LASEK in high myopic astigmatism for 3a88years. (22708970)
2012
17
Astigmatic changes after horizontal rectus muscle surgery in intermittent exotropia. (23204799)
2012
18
Toric soft contact lens fit in a postoperative LASIK keratoectasia patient with high and irregular astigmatism. (22019833)
2011
19
AcrySof IQ toric IOL implantation combined with limbal relaxing incision during cataract surgery for eyes with astigmatism >2.50 D. (21972447)
2011
20
Comparison of laser in situ keratomileusis for myopic astigmatism without iris registration, with iris registration, and with iris registration-assisted dynamic rotational eye tracking. (21333879)
2011
21
Power vector analysis of refractive, corneal, and internal astigmatism in an elderly Chinese population: the Shihpai Eye Study. (22110083)
2011
22
Corneal astigmatism correction with scleral flaps in trans-scleral suture-fixed posterior chamber lens implantation: a preliminary clinical observation. (22553711)
2011
23
Microincision cataract surgery with toric intraocular lens implantation for correcting moderate and high astigmatism: pilot study. (20117704)
2010
24
Surgically induced astigmatism after 23-gauge transconjunctival sutureless vitrectomy. (19696801)
2010
25
One-year follow-up of posterior chamber toric phakic intraocular lens implantation for moderate to high myopic astigmatism. (20598749)
2010
26
IntraLase-enabled astigmatic keratotomy for post-keratoplasty astigmatism: on-axis vector analysis. (20163860)
2010
27
Implantable Collamer Lens implantation and limbal relaxing incisions for the correction of hyperopic astigmatism after laser in situ keratomileusis. (19907310)
2010
28
Amblyopia in astigmatic infants and toddlers. (20351602)
2010
29
Correction of astigmatism after penetrating keratoplasty using the Acri.Comfort toric intraocular lens. (19912259)
2010
30
Static and dynamic rotational eye tracking during LASIK treatment of myopic astigmatism with the Zyoptix laser platform and Advanced Control Eye Tracker. (20199008)
2010
31
Approximate analytic astigmatism of unit-magnification multipass system. (20411007)
2010
32
Femtosecond laser arcuate keratotomy for the correction of high astigmatism after keratoplasty. (19395035)
2009
33
Correction of postkeratoplasty astigmatism by femtosecond laser compared with mechanized astigmatic keratotomy. (19232560)
2009
34
LASIK with the optimized aspheric transition zone and cross-cylinder technique for the treatment of astigmatism from 1.00 to 4.25 diopters. (19848372)
2009
35
Toric intraocular Collamer lens for high myopic astigmatism after penetrating keratoplasty. (19969225)
2009
36
Astigmatism and defocus wavefront correction via Zernike modes produced with fluidic lenses. (19571912)
2009
37
Prevalence of corneal astigmatism before cataract surgery. (19101427)
2009
38
Clinical outcomes of laser in situ keratomileusis using combined topography and refractive wavefront treatments for myopic astigmatism. (18655973)
2008
39
Limbal relaxing incisions to correct corneal astigmatism during phacoemulsification. (17523513)
2007
40
Corneal wedge excision in the treatment of high astigmatism after penetrating keratoplasty. (17667616)
2007
41
Astigmatism in children with epiblepharon. (17893541)
2007
42
Corneal astigmatism, high order aberrations, and optical quality after cataract surgery: microincision versus small incision. (17444097)
2006
43
Toric phakic intraocular lens for the correction of hyperopia and astigmatism. (16564999)
2006
44
Astigmatism in monkeys with experimentally induced myopia or hyperopia. (15829845)
2005
45
Modified astigmatism dial diagram for locating eccentric fixation in patients with central scotoma. (12749291)
2003
46
Surgical technique for control of postkeratoplasty myopia, astigmatism, and anisometropia. (12788120)
2003
47
Correction of irregular astigmatism with excimer laser assisted by sodium hyaluronate. (11425683)
2001
48
Refractive error changes in mixed astigmatism. (10768025)
1999
49
Laser in situ keratomileusis for hyperopia and hyperopic astigmatism. (9571548)
1998
50
LASIK for hyperopia and hyperopic astigmatism--results of a pilot study. (9758653)
1998

Genetic Variations for Astigmatism

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Expression for genes affiliated with Astigmatism

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Astigmatism

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Pathways for genes affiliated with Astigmatism

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Compounds for genes affiliated with Astigmatism

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GO Terms for genes affiliated with Astigmatism

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16Gene Ontology
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Biological processes related to Astigmatism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mesoderm developmentGO:00749810.3MATK, IRX3
2protein autophosphorylationGO:04677710.1EIF2AK2, FGFR3, MAP3K12
3regulation of protein stabilityGO:03164710.1ASPH, FBXO7

Products for genes affiliated with Astigmatism

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  • Antibodies
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Sources for Astigmatism

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet