MCID: AST002
MIFTS: 31

Astroblastoma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Astroblastoma

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Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Astroblastoma:

Name: Astroblastoma 11 48 54 50 13 68
 
Cerebral Astroblastoma 48

Characteristics:

Orphanet epidemiological data:

54
astroblastoma:
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: Adolescent,Adult,Childhood,Infancy

Classifications:



External Ids:

Disease Ontology11 DOID:7305
MeSH39 D018302
NCIt45 C4324
SNOMED-CT62 48952003
Orphanet54 ORPHA251679
UMLS via Orphanet69 C0334587
ICD10 via Orphanet31 C71.9

Summaries for Astroblastoma

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NIH Rare Diseases:48 Astroblastoma is a rare glial tumor usually located in the cerebral hemisphere of the brain. it can occur in individuals of any age, but occurs predominantly in children and young adults. signs and symptoms depend on the location and size of the tumor but most commonly include headaches and seizures. because these tumors are rare, there is little known regarding their behavior and how they should be managed. gross total resection (complete removal) of the tumor is recommended and is associated with a good prognosis for low-grade tumors. adjuvant therapy, including radiation and/or chemotherapy, is recommended for high-grade and recurrent cases (although its effectiveness is controversial). last updated: 9/4/2012

MalaCards based summary: Astroblastoma, also known as cerebral astroblastoma, is related to hypothalamic neoplasm and angiofollicular lymph hyperplasia. An important gene associated with Astroblastoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways are Neuroscience and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include brain, cerebellum and parietal lobe.

Wikipedia:71 Astroblastoma is a rare glial tumor derived from the astroblast, a type of cell that closely resembles... more...

Related Diseases for Astroblastoma

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Diseases related to Astroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 182)
idRelated DiseaseScoreTop Affiliating Genes
1hypothalamic neoplasm10.2GFAP, NES
2angiofollicular lymph hyperplasia10.2GFAP, NES
3childhood kidney cell carcinoma10.2GFAP, NES
4childhood embryonal testis carcinoma10.2GFAP, NES
5diabetes hypogonadism deafness mental retardation10.2GFAP, SYP
6papillary tumor of the pineal region10.2GFAP, SYP
7osteopetrosis, autosomal recessive 810.2GFAP, NES
8brain stem ependymoma10.2GFAP, SYP
9myelinoclastic diffuse sclerosis10.2ENO2, GFAP
10intrahepatic bile duct adenoma10.2GFAP, SYP
11pilocytic astrocytoma of cerebellum10.2GFAP, SYP
12bronchiolitis obliterans10.2GFAP, NES
13children's interstitial lung disease10.2GFAP, SYP
14thrombophlebitis10.2ENO2, GFAP
15cervical benign neoplasm10.2GFAP, SYP
16epidermal appendage tumor10.2GFAP, SYP
17clear cell meningioma10.2GFAP, SYP
18cerebral folate receptor alpha deficiency10.2GFAP, SYP
19pilocytic astrocytoma10.2GFAP, SYP
20pleomorphic xanthoastrocytoma10.2GFAP, SYP
21mediastinal granular cell myoblastoma10.2GFAP, SYP
22central neurocytoma10.2GFAP, SYP
23mast-cell sarcoma10.2GFAP, SYP
24olfactory neuroblastoma10.2GFAP, SYP
25jejunal somatostatinoma10.2ENO2, GFAP
26pineoblastoma10.2GFAP, SYP
27fallopian tube benign neoplasm10.2GFAP, NES
28pneumothorax10.2GFAP, SYP
29brain stem astrocytic neoplasm10.2GFAP, SYP
30brain oligodendroglioma10.2GFAP, SYP
31arthus reaction10.2GFAP, SYP
32bone dysplasia azouz type10.2GFAP, SYP
33pancreatic cancer10.2GFAP, SYP
34heavy chain disease10.2ENO2, GFAP
35pacinian tumor10.2GFAP, SYP
36temporal lobe neoplasm10.2GFAP, SYP
37melanotic neurilemmoma10.2GFAP, SYP
38infiltrating renal pelvis transitional cell carcinoma10.2ENO2, SYP
39thymus small cell carcinoma10.2ENO2, SYP
40skeletal-extraskeletal angiomatosis10.2ENO2, SYP
41prolactin producing pituitary tumor10.2ENO2, SYP
42glomus tumor10.2ENO2, SYP
43pemphigus foliaceus10.2ENO2, SYP
44spasmodic dysphonia10.2ENO2, SYP
45pneumonia10.2ENO2, GFAP
46cerebritis10.2
47ampullary signet ring cell adenocarcinoma10.2ENO2, SYP
48focal cortical dysplasia, taylor balloon cell type10.2GFAP, SYP
49perineural angioma10.2ENO2, SYP
50gliofibroma10.2ENO2, SYP

Graphical network of the top 20 diseases related to Astroblastoma:



Diseases related to astroblastoma

Symptoms & Phenotypes for Astroblastoma

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Drugs & Therapeutics for Astroblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Astroblastoma

Genetic Tests for Astroblastoma

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Anatomical Context for Astroblastoma

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MalaCards organs/tissues related to Astroblastoma:

36
Brain, Cerebellum, Parietal lobe, Hypothalamus, Temporal lobe, Spinal cord, Bone

Publications for Astroblastoma

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Articles related to Astroblastoma:

(show top 50)    (show all 80)
idTitleAuthorsYear
1
Genomic characterization of recurrent high-grade astroblastoma. (27425854)
2016
2
Astroblastoma: Case Report and Review of Literature. (27349390)
2016
3
A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study. (26614252)
2016
4
Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults. (27416954)
2016
5
Adult intraventricular astroblastoma. (26831319)
2016
6
Neuroradiologic characteristics of astroblastoma and systematic review of the literature: 2 new cases and 125 cases reported in 59 publications. (27048363)
2016
7
Hemorrhage in astroblastoma: An unusual manifestation of an extremely rare entity. (26547295)
2016
8
Distant dissemination of mixed low-grade astroblastoma-arteriovenous malformation after initial operation: a case report. (26261652)
2015
9
Well-differentiated and anaplastic astroblastoma in the same patient: a case report and review of the literature. (26227256)
2015
10
Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas? (25737639)
2015
11
Astroblastoma of cerebrum: A rare case report and review of literature. (26458709)
2015
12
Intraventricular Astroblastoma in an Infant: A Case Report and Review of the Literature. (26406441)
2015
13
Astroblastoma: report of two cases with unexpected clinical behavior and review of the literature. (25108699)
2014
14
Cerebral astroblastoma: A radiopathological diagnosis. (24891904)
2014
15
Astroblastoma: rare incidence and challenges in the pattern of care. (24607547)
2014
16
High-grade astroblastoma in a child: Report of one case and review of literature. (25101206)
2014
17
Cerebral astroblastoma in an adult: an immunohistochemical, ultrastructural and genetic study. (22994361)
2013
18
Recurrent low-grade astroblastoma with signet ring-like cells and high proliferative index. (23301912)
2013
19
Mixed astroblastoma-arteriovenous malformation complex: a case report. (24005749)
2013
20
Cerebral astroblastoma: A case report and review of literature. (22870162)
2012
21
Pediatric astroblastoma: a rare case with a review of the literature. (23038221)
2012
22
Astroblastoma - a case report of a rare neuroepithelial tumor with complete remission after chemotherapy. (22011735)
2011
23
Anaplastic astroblastoma: a rare glial tumour. (22679316)
2011
24
Astroblastoma with bone invasion. (22347336)
2011
25
A newborn with massive congenital astroblastoma. (21491993)
2011
26
Clinical features and post-surgical outcome of patients with astroblastoma. (21507653)
2011
27
Recurrent astroblastoma treated with gamma knife radiosurgery. (20938716)
2011
28
Anaplastic astroblastoma-sarcoma in neurofibromatosis Type 1. (20860891)
2010
29
Anaplastic astroblastoma presenting as massive, sudden-onset, intraparenchymal hemorrhage. (21540623)
2010
30
Two cases of pediatric high-grade astroblastoma with different clinical behavior. (20437876)
2010
31
Supratentorial high grade astroblastoma: report of two cases and review of the literature. (19431125)
2009
32
Unusual manifestations of astroblastoma: a radiologic-pathologic analysis. (18958463)
2009
33
Cerebral astroblastoma: analysis of six cases and critical review of treatment options. (19214707)
2009
34
Anaplastic astroblastoma of childhood: aggressive behavior. (19357852)
2009
35
A Cerebral Astroblastoma Mimicking an Extra-axial Neoplasm. (19096646)
2008
36
Consecutive histological changes in an astroblastoma that disseminated to the spinal cord after repeated intracranial recurrences: a case report. (18415663)
2008
37
Brainstem astroblastoma: a case report and review of the literature. (17765957)
2008
38
Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up. (18280055)
2008
39
Astroblastoma in a child. (17653728)
2008
40
Intraventricular astroblastoma. Case report. (18352788)
2008
41
An astroblastoma mimicking a cavernous malformation: case report. (17327764)
2007
42
Astroblastoma presenting with intracerebral hemorrhage misdiagnosed as dural arteriovenous fistula: review of a rare entity. (17320647)
2007
43
Astroblastoma. Case report, review of the literature, and analysis of treatment strategies. (17369788)
2007
44
Malignant astroblastoma with rhabdoid morphology. (17332948)
2007
45
Neuroradiologic characteristics of astroblastoma. (17216265)
2007
46
Low-grade astroblastoma recurring with extensive invasion. (16998280)
2006
47
An astroblastoma case associated with loss of heterozygosity on chromosome 9p. (16636749)
2006
48
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation. (16521483)
2006
49
Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature. (16565782)
2006
50
'Low-grade' astroblastoma with rapid recurrence: a case report. (16484017)
2006

Variations for Astroblastoma

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Expression for genes affiliated with Astroblastoma

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Search GEO for disease gene expression data for Astroblastoma.

Pathways for genes affiliated with Astroblastoma

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Pathways related to Astroblastoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.0ENO2, GFAP, SYP
2
Show member pathways
8.8GFAP, NES, VIM
38.3GFAP, NES, SYP, VIM

GO Terms for genes affiliated with Astroblastoma

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Cellular components related to Astroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.6GFAP, NES
2intermediate filamentGO:00058829.2GFAP, NES, VIM

Sources for Astroblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet