MCID: AST002
MIFTS: 31

Astroblastoma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Astroblastoma

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10 via Orphanet, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Astroblastoma:

Name: Astroblastoma 11 47 53 49 13 67
 
Cerebral Astroblastoma 47

Characteristics:

Orphanet epidemiological data:

53
astroblastoma:
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: Adolescent,Adult,Childhood,Infancy

Classifications:



External Ids:

Disease Ontology11 DOID:7305
MeSH38 D018302
NCIt44 C4324
SNOMED-CT61 48952003
Orphanet53 ORPHA251679
UMLS via Orphanet68 C0334587
ICD10 via Orphanet30 C71.9

Summaries for Astroblastoma

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Wikipedia:70 Astroblastoma is a rare glial tumor derived from the astroblast, a type of cell that closely resembles... more...

MalaCards based summary: Astroblastoma, also known as cerebral astroblastoma, is related to empty sella syndrome and anaplastic oligodendroglioma. An important gene associated with Astroblastoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways are Spinal Cord Injury and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, cerebellum and parietal lobe.

Related Diseases for Astroblastoma

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Diseases related to Astroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 112)
idRelated DiseaseScoreTop Affiliating Genes
1empty sella syndrome10.3GFAP, NES
2anaplastic oligodendroglioma10.3GFAP, NES
3chondroblastoma10.3GFAP, VIM
4cervical alveolar soft part sarcoma10.3GFAP, NES
5pulmonary venoocclusive disease10.3GFAP, VIM
6congenital structural myopathy10.3GFAP, VIM
7subependymal giant cell astrocytoma10.3GFAP, VIM
8uterine corpus epithelioid leiomyosarcoma10.2GFAP, NES
9vascular hemostatic disease10.2GFAP, VIM
10gangliocytoma10.2GFAP, VIM
11grubben de cock borghgraef syndrome10.2GFAP, SYP
12papillary glioneuronal tumor10.2GFAP, SYP
13bladder flat intraepithelial lesion10.2GFAP, SYP
14lice infestation10.2GFAP, SYP
15chiari malformation type 410.2GFAP, SYP
16perivascular epithelioid cell tumor10.2GFAP, VIM
17cauda equina neoplasm10.2GFAP, SYP
18glomus tumor10.2GFAP, SYP
19vulvar benign neoplasm10.2GFAP, SYP
20cervical benign neoplasm10.2GFAP, NES
21hypersensitivity reaction type ii disease10.2GFAP, SYP
22brainstem intraparenchymal clear cell meningioma10.2GFAP, SYP
23oligoastrocytoma10.2NES, VIM
24atypical choroid plexus papilloma10.2GFAP, SYP
25pilomyxoid astrocytoma10.2GFAP, SYP
26cauda equina intradural extramedullary astrocytoma10.2GFAP, SYP
272q33.1 microdeletion syndrome10.2SYP, VIM
28choroid disease10.2GFAP, SYP
29vitamin metabolic disorder10.2GFAP, SYP
30plexopathy10.2GFAP, SYP
31cerebritis10.2
32malignant granular cell esophageal tumor10.2GFAP, SYP
33malignant pineal area germ cell neoplasm10.2GFAP, SYP
34diencephalic astrocytomas10.2GFAP, SYP
35osteopetrosis and infantile neuroaxonal dystrophy10.2NES, VIM
36pulmonary plasma cell granuloma10.1GFAP, SYP
37anaplastic oligoastrocytoma10.1SYP, VIM
38fraxf syndrome10.1SYP, VIM
39bone marrow cancer10.1GFAP, VIM
40spinal cord glioma10.1GFAP, SYP
41large intestine lipoma10.1GFAP, SYP
42epidermal nevus vitamin d resistant rickets10.1SYP, VIM
43o'sullivan-mcleod syndrome10.1NES, VIM
44neurilemmoma of the fifth cranial nerve10.1GFAP, SYP
45skin glomangioma10.1SYP, VIM
46female reproductive endometrioid cancer10.1SYP, VIM
47peritoneal benign neoplasm10.1GFAP, SYP
48mesenchymoma10.1GFAP, SYP
49parachordoma10.1SYP, VIM
50angora hair nevus10.1SYP, VIM

Graphical network of the top 20 diseases related to Astroblastoma:



Diseases related to astroblastoma

Symptoms for Astroblastoma

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Drugs & Therapeutics for Astroblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Astroblastoma

Genetic Tests for Astroblastoma

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Anatomical Context for Astroblastoma

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MalaCards organs/tissues related to Astroblastoma:

35
Brain, Cerebellum, Parietal lobe, Hypothalamus, Temporal lobe, Spinal cord, Bone

Animal Models for Astroblastoma or affiliated genes

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Publications for Astroblastoma

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Articles related to Astroblastoma:

(show top 50)    (show all 80)
idTitleAuthorsYear
1
Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults. (27416954)
2016
2
Neuroradiologic characteristics of astroblastoma and systematic review of the literature: 2 new cases and 125 cases reported in 59 publications. (27048363)
2016
3
Hemorrhage in astroblastoma: An unusual manifestation of an extremely rare entity. (26547295)
2016
4
Genomic characterization of recurrent high-grade astroblastoma. (27425854)
2016
5
Astroblastoma: Case Report and Review of Literature. (27349390)
2016
6
A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study. (26614252)
2016
7
Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas? (25737639)
2015
8
Distant dissemination of mixed low-grade astroblastoma-arteriovenous malformation after initial operation: a case report. (26261652)
2015
9
Astroblastoma of cerebrum: A rare case report and review of literature. (26458709)
2015
10
High-grade astroblastoma in a child: Report of one case and review of literature. (25101206)
2014
11
Astroblastoma: rare incidence and challenges in the pattern of care. (24607547)
2014
12
Cerebral astroblastoma: A radiopathological diagnosis. (24891904)
2014
13
Mixed astroblastoma-arteriovenous malformation complex: a case report. (24005749)
2013
14
Recurrent low-grade astroblastoma with signet ring-like cells and high proliferative index. (23301912)
2013
15
Pediatric astroblastoma: a rare case with a review of the literature. (23038221)
2012
16
Anaplastic astroblastoma: a rare glial tumour. (22679316)
2011
17
Astroblastoma with bone invasion. (22347336)
2011
18
Recurrent astroblastoma treated with gamma knife radiosurgery. (20938716)
2011
19
Clinical features and post-surgical outcome of patients with astroblastoma. (21507653)
2011
20
Two cases of pediatric high-grade astroblastoma with different clinical behavior. (20437876)
2010
21
Anaplastic astroblastoma presenting as massive, sudden-onset, intraparenchymal hemorrhage. (21540623)
2010
22
Supratentorial high grade astroblastoma: report of two cases and review of the literature. (19431125)
2009
23
Anaplastic astroblastoma of childhood: aggressive behavior. (19357852)
2009
24
Unusual manifestations of astroblastoma: a radiologic-pathologic analysis. (18958463)
2009
25
Astroblastoma in a child. (17653728)
2008
26
Intraventricular astroblastoma. Case report. (18352788)
2008
27
Brainstem astroblastoma: a case report and review of the literature. (17765957)
2008
28
Consecutive histological changes in an astroblastoma that disseminated to the spinal cord after repeated intracranial recurrences: a case report. (18415663)
2008
29
Astroblastoma. Case report, review of the literature, and analysis of treatment strategies. (17369788)
2007
30
Malignant astroblastoma with rhabdoid morphology. (17332948)
2007
31
'Low-grade' astroblastoma with rapid recurrence: a case report. (16484017)
2006
32
An astroblastoma case associated with loss of heterozygosity on chromosome 9p. (16636749)
2006
33
Low-grade astroblastoma recurring with extensive invasion. (16998280)
2006
34
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation. (16521483)
2006
35
Low-grade glial tumor with features of astroblastoma in a dog. (15872386)
2005
36
Astroblastoma in childhood: pathological and clinical analysis. (15654633)
2005
37
Astroblastoma with unusual signet-ring-like cell components: a case report and literature review. (12416560)
2002
38
Astroblastoma: clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization. (10885653)
2000
39
Astroblastoma: report of a case with microsatellite analysis. (11132940)
2000
40
Astroblastoma: ultrastructural observations on a case of high-grade type. (10582270)
1999
41
Congenital astroblastoma: an immunohistochemical study. Case report. (7545227)
1995
42
Astroblastoma: report of a case with ultrastructural, cell kinetic, and cytogenetic analysis. (8516227)
1993
43
Astroblastoma: electron microscopy and immunohistochemical findings: case report. (1990478)
1991
44
The fine structure of astroblastoma. (3967170)
1985
45
Activation of acetyl- and butyrylcholinesterase by enzymatic removal of sialic acid from intact neuroblastoma and astroblastoma cells in culture. (172121)
1975
46
Clinical pathological conference; astroblastoma. (14899596)
1952
47
A study of 182 patients with verified astrocytoma, astroblastoma and oligodendroglioma of the brain. (15422396)
1950
48
Astroblastoma and perithelial sarcoma in a case of neoplastic disease of the brain. (18125890)
1949
49
Astroblastoma of the brain with sudden death. (15406883)
1949
50
Astroblastoma of the cerebellum in an infant; report of a case. (18134318)
1949

Variations for Astroblastoma

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Expression for genes affiliated with Astroblastoma

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Search GEO for disease gene expression data for Astroblastoma.

Pathways for genes affiliated with Astroblastoma

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GO Terms for genes affiliated with Astroblastoma

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Cellular components related to Astroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell projectionGO:00429959.5GFAP, VIM
2intermediate filament cytoskeletonGO:00451119.4GFAP, NES, VIM
3intermediate filamentGO:00058829.4GFAP, NES, VIM

Biological processes related to Astroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:00600209.8GFAP, VIM
2intermediate filament-based processGO:00451039.8GFAP, VIM
3negative regulation of neuron projection developmentGO:00109779.5GFAP, VIM
4intermediate filament organizationGO:00451099.4GFAP, VIM
5astrocyte developmentGO:00140029.2GFAP, VIM

Molecular functions related to Astroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.5GFAP, VIM
2glycoprotein bindingGO:00019489.2GFAP, VIM
3structural molecule activityGO:00051989.0GFAP, NES, VIM

Sources for Astroblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet