MCID: ATX030
MIFTS: 78

Ataxia-Telangiectasia malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Reproductive diseases, Skin diseases, Endocrine diseases, Fetal diseases, Blood diseases, Immune diseases, Ear diseases

Aliases & Classifications for Ataxia-Telangiectasia

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Aliases & Descriptions for Ataxia-Telangiectasia:

Name: Ataxia-Telangiectasia 50 22 23 24 52 68 12
Ataxia Telangiectasia 33 11 69 46 23 47 13 68 48 36 37 66
Louis-Bar Syndrome 22 46 23 24 52 68
Ataxia-Telangiectasia Variant 52 25 66
a-T 23 24
at 46 68
Immunodeficiency with Ataxia Telangiectasia 46
Telangiectasia, Cerebello-Oculocutaneous 24
 
Cerebello-Oculocutaneous Telangiectasia 46
Ataxia Telangiectasia Syndrome 24
Boder-Sedgwick Syndrome 11
Louis Bar Syndrome 11
V-at 52
Atm 24
At1 68

Characteristics:

Orphanet epidemiological data:

52
ataxia-telangiectasia:
Inheritance: Autosomal recessive; Prevalence: 1-5/10000 (Norway),1-9/1000000 (Norway),1-9/100000 (United States),1-9/1000000 (Europe),1-9/1000000 (Portugal),1-9/1000000 (France),1-9/100000 (Italy); Age of onset: Childhood,Infancy; Age of death: adult

HPO:

62
ataxia-telangiectasia:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM50 208900
Disease Ontology11 DOID:12704
MeSH37 D001260
NCIt43 C2887
SNOMED-CT60 68504005
ICD10 via Orphanet29 G11.3
MESH via Orphanet38 D001260
UMLS via Orphanet67 C0004135

Summaries for Ataxia-Telangiectasia

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Genetics Home Reference:24 Ataxia-telangiectasia is a rare inherited disorder that affects the nervous system, immune system, and other body systems. This disorder is characterized by progressive difficulty with coordinating movements (ataxia) beginning in early childhood, usually before age 5. Affected children typically develop difficulty walking, problems with balance and hand coordination, involuntary jerking movements (chorea), muscle twitches (myoclonus), and disturbances in nerve function (neuropathy). The movement problems typically cause people to require wheelchair assistance by adolescence. People with this disorder also have slurred speech and trouble moving their eyes to look side-to-side (oculomotor apraxia). Small clusters of enlarged blood vessels called telangiectases, which occur in the eyes and on the surface of the skin, are also characteristic of this condition.

MalaCards based summary: Ataxia-Telangiectasia, also known as ataxia telangiectasia, is related to familial breast cancer and breast cancer, and has symptoms including polycystic ovaries, strabismus and nystagmus. An important gene associated with Ataxia-Telangiectasia is ATM (ATM Serine/Threonine Kinase), and among its related pathways are miRNA Regulation of DNA Damage Response and PLK3 signaling events. Affiliated tissues include eye, skin and brain, and related mouse phenotypes are pigmentation and integument.

NIH Rare Diseases:46 Ataxia telangiectasia (a-t) is rare condition that affects the nervous system, the immune system, and many other parts of the body. signs and symptoms of the condition usually begin in early childhood, often before age 5. the condition is typically characterized by cerebellar ataxia (uncoordinated muscle movements), oculomotor apraxia, telangiectasias, choreoathetosis (uncontrollable movements of the limbs), a weakened immune system with frequent infections, and an increased risk of cancers such as leukemia and lymphoma. a-t is caused by changes (mutations) in the atm gene and is inherited in an autosomal recessive manner. treatment is supportive and based on the signs and symptoms present in each person. last updated: 4/5/2016

UniProtKB/Swiss-Prot:68 Ataxia telangiectasia: A rare recessive disorder characterized by progressive cerebellar ataxia, dilation of the blood vessels in the conjunctiva and eyeballs, immunodeficiency, growth retardation and sexual immaturity. Patients have a strong predisposition to cancer; about 30% of patients develop tumors, particularly lymphomas and leukemias. Cells from affected individuals are highly sensitive to damage by ionizing radiation and resistant to inhibition of DNA synthesis following irradiation.

MedlinePlus:36 Ataxia-telangiectasia (a-t) is a rare, inherited disease. it affects the nervous system, immune system, and other body systems. symptoms appear in young children, usually before age 5. they include ataxia - trouble coordinating movements poor balance slurred speech tiny, red spider veins, called telangiectasias, on the skin and eyes lung infections delayed physical and sexual development people with a-t have an increased risk of developing diabetes and cancers, especially lymphoma and leukemia. although it affects the brain, people with a-t usually have normal or high intelligence. a-t has no cure. treatments might improve some symptoms. they include injections to strengthen the immune system, physical and speech therapy, and high-dose vitamins. nih: national institute of neurological disorders and stroke

NINDS:47 Ataxia-telangiectasia is a rare, childhood neurological disorder that causes degeneration in the part of the brain that controls motor movements and speech. The first signs of the disease are unsteady walking and slurred speech, usually occurring during the first five years of life. Telangiectasias (tiny, red "spider" veins), which appear in the corners of the eyes or on the surface of the ears and cheeks, are characteristic of the disease, but are not always present and generally do not appear in the first years of life. About 35 percent of those with A-T develop cancer, most frequently acute lymphocytic leukemia or lymphoma. The most unusual symptom is an acute sensitivity to ionizing radiation, such as X-rays or gamma rays.

OMIM:50 Ataxia-telangiectasia (AT) is an autosomal recessive disorder characterized by cerebellar ataxia, telangiectases,... (208900) more...

Wikipedia:69 Ataxia telangiectasia (A-T) (also referred to as Louis–Bar syndrome ) is a rare, neurodegenerative,... more...

GeneReviews summary for NBK26468

Related Diseases for Ataxia-Telangiectasia

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Diseases in the Ataxia-Telangiectasia family:

Ataxia-Telangiectasia-Like Disorder

Diseases related to Ataxia-Telangiectasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 166)
idRelated DiseaseScoreTop Affiliating Genes
1familial breast cancer31.2BRCA1, CHEK2
2breast cancer29.3AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK1
3ataxia-telangiectasia-like disorder12.6
4nijmegen breakage syndrome12.0
5cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk11.9
6pulmonary fungal infections in patients deemed at risk11.9
7poliomyelitis in patients with immunodeficiencies deemed at risk11.9
8arterial tortuosity syndrome11.6
9ataxia11.4
10atypical teratoid rhabdoid tumor11.3
11ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia11.1
12asphyxiating thoracic dystrophy11.1
13liddle syndrome, scnn1g-related10.8CHEK2, TP53
14lethal congenital contracture syndrome 710.7BRCA1, NBN
15ocular motor apraxia10.7
16cervical serous adenocarcinoma10.7BRCA1, TP53
17simple partial epilepsy10.7PCNA, TP53
18bile duct disease10.7ATM, BRCA1, TP53
19breast cancer, childhood10.6BRCA1, CHEK2, NBN
20internal auditory canal lipoma10.6ATM, BRCA1, CHEK2
21leukemia10.6
22lymphoma10.6
23bejel10.6ATM, BRCA1, CHEK1
24lung acinar adenocarcinoma10.5CDKN1A, TP53
25janus kinase-3 deficiency10.5DCLRE1C, H2AFX, PRKDC
26pineal region meningioma10.5ATM, BRCA1, CHEK2, TP53
27ureter inverted papilloma10.5CDKN1A, TP53
28amyloid tumor10.5ATM, BRCA1
29gastrointestinal system cancer10.5BRCA1, CDKN1A, TP53
30arthrogryposis, renal dysfunction, and cholestasis 110.5ATM, BRCA1, H2AFX
31mixed endometrial stromal and smooth muscle tumor10.5CDKN1A, TP53
32lung cancer10.4
33dysostosis10.4BRCA1, CDKN1A, TP53
34diamond-blackfan anemia 510.4BRCA1, TP53BP1
35brittle bone syndrome lethal type10.3ATM, BRCA1, CHEK2, RAD50, TP53
36hodgkin lymphoma10.3
37cd40 deficiency10.3ATM, ATR, DCLRE1C, NBN, PRKDC
38lymphoblastic leukemia10.3
39neuronitis10.3
40gastric cancer10.3
41dystonia10.3
42nasopharyngeal carcinoma10.2ATM, BRCA1, CDKN1A, CHEK2, TP53
43milker's nodule10.2AGTR1, BRCA1, TP53
44charcot-marie-tooth disease, type 4b110.2ATM, CHEK2, MRE11A, NBN, PCNA, RAD50
45bloom syndrome10.2
46b-cell lymphomas10.2
47chronic lymphocytic leukemia10.2
48hepatitis10.2
49adenocarcinoma10.2
50cerebritis10.2

Graphical network of the top 20 diseases related to Ataxia-Telangiectasia:



Diseases related to ataxia-telangiectasia

Symptoms for Ataxia-Telangiectasia

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Symptoms by clinical synopsis from OMIM:

208900

Clinical features from OMIM:

208900

Symptoms:

 52 (show all 37)
  • abnormality of the testis
  • polycystic ovaries
  • strabismus
  • abnormality of eye movement
  • nystagmus
  • diabetes mellitus
  • delayed puberty
  • seizures
  • ataxia
  • spasticity
  • dysarthria
  • gait disturbance
  • tremor
  • failure to thrive
  • lymphopenia
  • neurological speech impairment
  • recurrent respiratory infections
  • premature graying of hair
  • neoplasm
  • abnormality of the immune system
  • immunodeficiency
  • elevated hepatic transaminases
  • skeletal muscle atrophy
  • abnormality of chromosome stability
  • hypogammaglobulinemia
  • short stature
  • cellular immunodeficiency
  • hypopigmentation of hair
  • type ii diabetes mellitus
  • prematurely aged appearance
  • multiple cafe-au-lait spots
  • aplasia/hypoplasia of the skin
  • aplasia/hypoplasia of the thymus
  • abnormality of movement
  • cognitive impairment
  • mucosal telangiectasiae
  • teleangiectasia of the skin

HPO human phenotypes related to Ataxia-Telangiectasia:

(show all 61)
id Description Frequency HPO Source Accession
1 polycystic ovaries hallmark (90%) HP:0000147
2 strabismus hallmark (90%) HP:0000486
3 nystagmus hallmark (90%) HP:0000639
4 gait disturbance hallmark (90%) HP:0001288
5 tremor hallmark (90%) HP:0001337
6 lymphopenia hallmark (90%) HP:0001888
7 neurological speech impairment hallmark (90%) HP:0002167
8 recurrent respiratory infections hallmark (90%) HP:0002205
9 premature graying of hair hallmark (90%) HP:0002216
10 incoordination hallmark (90%) HP:0002311
11 elevated hepatic transaminases hallmark (90%) HP:0002910
12 abnormality of chromosome stability hallmark (90%) HP:0003220
13 decreased antibody level in blood hallmark (90%) HP:0004313
14 cellular immunodeficiency hallmark (90%) HP:0005374
15 aplasia/hypoplasia of the thymus hallmark (90%) HP:0010515
16 mucosal telangiectasiae hallmark (90%) HP:0100579
17 telangiectasia of the skin hallmark (90%) HP:0100585
18 seizures typical (50%) HP:0001250
19 hypertonia typical (50%) HP:0001276
20 neurological speech impairment typical (50%) HP:0002167
21 neoplasm typical (50%) HP:0002664
22 skeletal muscle atrophy typical (50%) HP:0003202
23 short stature typical (50%) HP:0004322
24 hypopigmentation of hair typical (50%) HP:0005599
25 abnormality of the testis occasional (7.5%) HP:0000035
26 cafe-au-lait spot occasional (7.5%) HP:0000957
27 type ii diabetes mellitus occasional (7.5%) HP:0005978
28 aplasia/hypoplasia of the skin occasional (7.5%) HP:0008065
29 cognitive impairment occasional (7.5%) HP:0100543
30 female hypogonadism HP:0000134
31 sinusitis HP:0000246
32 strabismus HP:0000486
33 conjunctival telangiectasia HP:0000524
34 nystagmus HP:0000639
35 hypoplasia of the thymus HP:0000778
36 diabetes mellitus HP:0000819
37 delayed puberty HP:0000823
38 glucose intolerance HP:0000833
39 cafe-au-lait spot HP:0000957
40 seizures HP:0001250
41 ataxia HP:0001251
42 dysarthria HP:0001260
43 choreoathetosis HP:0001266
44 reduced tendon reflexes HP:0001315
45 dystonia HP:0001332
46 myoclonus HP:0001336
47 tremor HP:0001337
48 abnormality of the hair HP:0001595
49 lymphopenia HP:0001888
50 leukemia HP:0001909
51 bronchiectasis HP:0002110
52 iga deficiency HP:0002720
53 recurrent bronchitis HP:0002837
54 short stature HP:0004322
55 defective b cell differentiation HP:0005357
56 decreased number of cd4+ t cells HP:0005407
57 elevated alpha-fetoprotein HP:0006254
58 immunoglobulin igg2 deficiency HP:0008348
59 abnormal spermatogenesis HP:0008669
60 hodgkin lymphoma HP:0012189
61 non-hodgkin lymphoma HP:0012539

UMLS symptoms related to Ataxia-Telangiectasia:


back pain, cerebellar ataxia, headache, myoclonus, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness, cerebellar ataxia/dyskinesia

Drugs & Therapeutics for Ataxia-Telangiectasia

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Drugs for Ataxia-Telangiectasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 38)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AmantadinePhase 466768-94-52130
Synonyms:
1-Adamantamine
1-Adamantanamine
1-Adamantanamine (8CI)
1-Adamantylamine
1-Aminoadamantane
1-Aminotricyclo(3.3.1.1(sup 3,7))decane
1-adamantanamine
1-adamantylamine
1-aminoadamantane
138576_ALDRICH
665-66-7 (hydrochloride)
768-94-5
AB00514655
AC-11992
AC1L1CZI
AC1Q4UAF
AC1Q5396
ADAMANTANE,1-AMINO
AKOS000113994
AKOS000119324
Adamantamine
Adamantanamine
Adamantylamine
Amant
Amantadina
Amantadina [INN-Spanish]
Amantadine
Amantadine (INN)
Amantadine Base
Amantadine HCL
Amantadine Hydrochloride
Amantadine [INN:BAN]
Amantadinum
Amantadinum [INN-Latin]
Amantidine
Ambap768-94-5
Aminoadamantane
BIA4304
BIDD:GT0757
BPBio1_000368
BRN 2204333
BSPBio_000334
BSPBio_001570
BSPBio_001822
Bio-0821
C06818
C10H17N
CHEBI:2618
CHEMBL660
CID2130
D07441
DB00915
DivK1c_000815
EINECS 212-201-2
Endantadine
Gen-Amantadine
HMS1791O12
HMS1989O12
HSDB 3202
I14-1101
IDI1_000815
InChI=1/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H
KBio1_000815
KBio2_000390
 
KBio2_002958
KBio2_005526
KBio3_001322
KBioGR_000548
KBioSS_000390
L000868
LS-157049
Lopac-A-1260
Lopac0_000004
Mantadine
MolPort-001-661-700
MolPort-001-760-587
MolPort-001-791-102
NCGC00015036-01
NCGC00015036-07
NCGC00162039-01
NCGC00162039-02
NCGC00162039-03
NCGC00162039-04
NCGC00179597-01
NCIOpen2_001059
NINDS_000815
NSC 341865
NSC341865
NSC83653
OR14310
Oprea1_248648
Pk-Merz
Pk-merz
Prestwick0_000407
Prestwick1_000407
Prestwick2_000407
Prestwick3_000407
SPBio_000002
SPBio_002273
STK298781
Spectrum2_000081
Spectrum3_000291
Spectrum4_000134
Spectrum5_000772
Spectrum_000030
Symadine
Symmetrel
TCMDC-125869
TL8005280
Tricyclo(3.3.1.1(3,7))-decan-1-amine
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine
Tricyclo(3.3.1.1(sup 3.7))decan-1-amine
Tricyclo(3.3.1.13,7)decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-ylamine
Tricyclo[3.3.1.1(3,7)]decane-1-amine
Tricyclo[3.3.1.1(sup3,7)]decan-1-amine
Tricyclo[3.3.1.1^3,7]decan-1-amine
UNII-BF4C9Z1J53
Viregyt
Virosol
WLN: L66 B6 A B- C 1B ITJ BZ
Wiregyt
adamantan-1-amine
adamantan-1-ylamine
amantadine
amantadine hydrochloride
tricyclo[3.3.1.1(3,7)]decan-1-ylamine
tricyclo[3.3.1.1(3,7)]decane-1-amine
tricyclo[3.3.1.1~3,7~]decan-1-amine
2
DopaminePhase 4367851-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
3insulinPhase 44401
4Estradiol valeratePhase 41250979-32-8
5
EstradiolPhase 4125050-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol [USAN:INN]
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
 
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
6
clonidinePhase 42194205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
7
PioglitazonePhase 4428111025-46-84829
Synonyms:
(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
(+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
105355-27-9
111025-46-8
198077-89-3
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI)
5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
AB1004597
AC-1021
AC1L1J1Q
AD 4833
AD-4833
Actos
Actos (TN)
Actost
BRD-A48430263-003-02-4
BSPBio_002723
C07675
C19H20N2O3S
CHEBI:8228
CHEMBL595
CID4829
D08378
DB01132
Duetact
Glustin
HMS2089H14
HS-0047
 
HSDB 7322
I06-0089
KBio2_002103
KBio2_004671
KBio2_007239
KBio3_001943
KBioGR_001619
KBioSS_002103
LS-151327
MolPort-002-508-211
NCGC00163128-01
NCGC00163128-02
Pioglitazona
Pioglitazona [INN-Spanish]
Pioglitazone
Pioglitazone HCl
Pioglitazone Hydrochloride
Pioglitazone [BAN:INN]
Pioglitazone [Ban:Inn]
Pioglitazone [INN:BAN]
Pioglitazonum
Pioglitazonum [INN-Latin]
SPBio_001897
Spectrum2_001679
Spectrum3_001002
Spectrum4_001130
Spectrum5_001480
Spectrum5_002067
Spectrum_001623
U 72107
U 72107A
U-72107
U72,107A
UNII-X4OV71U42S
Zactos
nchembio790-comp10
pioglitazone (INN)
pioglitazone HCl
8
MetforminPhase 41701657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
9arginineNutraceuticalPhase 4393
10glucocorticoidsPhase 34756
11
DexamethasonePhase 3200150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
12Dexamethasone acetatePhase 320011177-87-3
13
protease inhibitorsPhase 35157
Synonyms:
 
protease inhibitors
14
MiconazolePhase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
15
CaspofunginPhase 264179463-17-3, 162808-62-0468682, 2826718
Synonyms:
(4R,5S)-5-((2-Aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(P-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
(4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
(4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin b0
1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0
162808-62-0
AC1L45LR
AC1LAHR5
AC1MCVUN
AR-1K4318
CASPO
CHEBI:474180
CHEMBL374999
CHEMBL499808
CID151068
CID2826718
CID468682
Cancidas
Cancidas (TM)
 
Cancidas (TN)
Capsofungin
Caspofungin
Caspofungin (INN)
Caspofungin [INN]
D07626
DB00520
HSDB 7476
L-743,872
LS-186994
LS-187303
LS-187635
M991
MK-0991
N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide
Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]- (9CI)
UNII-F0XDI6ZL63
[1(R)-hydroxyethyl]-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0(9,13)]heptacosane-2,5,8,14,17,23-hexaone diacetate
n-{(2r,6s,9s,11r,12s,14as,15s,20s,23s,25as)-12-[(2-aminoethyl)amino]-20-[(1r)-3-amino-1-hydroxypropyl]-23-[(1s,2s)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1r)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1h-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide
nchembio.184-comp7
16
GemcitabinePhase 2192895058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
17
PaclitaxelPhase 2, Phase 1269133069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nab-paclitaxel
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
18
OlaparibPhase 2117763113-22-023725625
Synonyms:
4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one
4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
763113-22-0
937799-91-2
AKOS005145764
AZD 2281
AZD-2281
AZD2281
 
Acylpiperazine analogue, 47
CHEMBL521686
EC-000.2324
EN002690
FT-0083489
KU-0059436
KU-59436
Olaparib
Olaparib, KU-0059436, AZD2281, KU0059436, AZD2281
S1060_Selleck
olaparib
19topoisomerase I inhibitorsPhase 11313
20
CamptothecinPhase 15697689-03-4
Synonyms:
(+)-camptothecin
(+)-camptothecine
(s)-(+)-camptothecin
 
(s)-camptothecin
20(S)-Camptothecin
21,22-Secocamptothecin-21-oic acid lactone
Camptothecine
D-camptothecin
21
IrinotecanPhase 1106297682-44-5, 100286-90-660838
Synonyms:
(+)-Irinotecan
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
1u65
97682-44-5
AC-7469
AC1L1U0Z
AC1Q6PGI
BRD-K08547377-003-02-4
BSPBio_002346
Bio-0054
Biotecan
Biotecan (TN)
C16641
C33H38N4O6
CHEBI:105985
CHEMBL481
CID60838
CP0
Campothecin-11
Campto
Camptosar
 
Camptosar, Campto, CPT-11, Irinotecan
Camptothecin-11
D08086
DB00762
FT-0083650
HSDB 7607
IRINOTECAN HYDROCHLORIDE Trihydrate
IRINOTECAN, CPT-11
Irinotecan (INN)
Irinotecan Hcl
Irinotecan Hydrochloride
Irinotecan Hydrochloride Trihydrate
Irinotecan [INN:BAN]
Irinotecan hydrochloride
Irinotecanum
Irinotecanum [INN-Latin]
LS-44589
NCI60_005051
NSC728073
S1198_Selleck
TL8006026
UNII-7673326042
irinotecan
22
DoxilApproved June 1999167631703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
23
Prednisone131853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
24
Methotrexate14961959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
25
Procarbazine69671-16-94915
Synonyms:
1-Methyl-2-(P-(isopropylcarbamoyl)benzyl)hydrazine
1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine
2-(P-Isopropylcarbamoylbenzyl)-1-methylhydrazine
2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine
366-70-1 (mono-hydrochloride)
4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide
671-16-9
AC-4547
AC1L1J8E
Ambap671-16-9
BIDD:GT0183
BPBio1_001369
BRN 0958270
BSPBio_001244
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)- (9CI)
C07402
C12H19N3O
CAS-366-70-1
CB 400-497
CCRIS 2389
CHEMBL1321
CID4915
D08423
DB01168
EINECS 211-582-2
HMS2090J09
HSDB 3250
I01-8931
IBZ
Ibenzmethyzin
Ibenzmethyzine
LS-7671
MBH
MIH
MolPort-005-940-370
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
 
N-(1-Methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
N-4-Isopropylcarbamoylbenzyl-n'-methylhydrazine
N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide
N-Isopropyl-P-(2-methylhydrazinomethyl)-benzamide
N-Isopropyl-alpha-(2-methylhydrazino)-P-toluamide
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
NCGC00016438-01
NCGC00016438-02
NCI60_041703
NCIOpen2_004074
NSC-77213
Natulan
Natulanar
P-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
PCX
Prestwick0_001112
Prestwick1_001112
Prestwick2_001112
Prestwick3_001112
Procarbazin
Procarbazin [German]
Procarbazina
Procarbazina [INN-Spanish]
Procarbazine (INN)
Procarbazine Monohydrochloride
Procarbazine [INN:BAN]
Procarbazinum
Procarbazinum [INN-Latin]
Ro 4-6467
Ro 4-6467/1
SPBio_003112
SRI-10847
UNII-35S93Y190K
p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide
procarbazine
26
Vincristine8882068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
27
Vinblastine398865-21-413342, 241903
Synonyms:
(2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine
(2xi,3beta,4'beta,19xi)-vincaleukoblastine
(3aR-(3aalpha,4beta,5beta,5abeta,9(3R*,5S*,7R*,9S*),10bR*,13aalpha))-methyl 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino(8,1-cd)carbazole-5-carboxylate
143-67-9
1z2b
29060-LE
865-21-4
AC-20335
AC1L21JC
AC1L68D2
AC1MXZJ2
BIDD:PXR0201
BRD-K01188359-065-02-5
BSPBio_001228
BSPBio_003594
Bio-0111
C07201
C46H58N4O9
CCRIS 9002
CHEBI:171516
CHEBI:27375
CHEMBL159
CHEMBL607706
CID13342
CID241903
CID3823887
CID6710780
D08675
DB00570
EINECS 212-734-0
HMS2090K05
HSDB 3263
KBio3_003033
LS-1859
LS-187263
 
MolPort-002-518-262
MolPort-005-910-359
NCGC00022585-04
NCGC00181127-01
NCI-C04842
NCI60_004200
NChemBio.2007.10-comp22
NDC 0002-1452-01
NSC 47842
Neuro_000020
Nincaluicolflastine
Rozevin
SPBio_000680
STOCK1N-38480
Spectrum2_000890
Spectrum3_001994
UNII-5V9KLZ54CY
VLB
VR-8
Velban
Velbe
Vinblastin
Vinblastina
Vinblastina (TN)
Vinblastina [DCIT]
Vinblastina [Dcit]
Vinblastine
Vinblastine (INN)
Vinblastine Sulfate
Vinblastine [INN:BAN]
Vinblastinum
Vinblastinum [INN-Latin]
Vincaleucoblastin
Vincaleucoblastine
Vincaleukoblastine
Vincoblastine
nchembio873-comp22
vinblastine
28
Etoposide121033419-42-036462
Synonyms:
(-)-Etoposide
121471-01-0
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
51854-34-3
76576-58-4
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one
AB00438905
AC1L1FN8
AC1L1VT3
AC1L6246
AC1NR4OG
AC1O4WGG
AC1O7M1N
AC1Q47JJ
Ambap33419-42-0
BPBio1_000673
BRD-K37798499-001-02-5
BSPBio_000611
Bio1_000489
Bio1_000978
Bio1_001467
C01576
CCRIS 2392
CHEBI:4911
CHEBI:588795
CHEMBL44657
CID11758093
CID284997
CID3310
CID36462
CID5284558
CID6419930
CID6610299
CPD000112002
D00125
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
E0675
E1383_SIGMA
EINECS 251-509-1
EPE
EPEG
ETOP
Epipodophyllotoxin
Epipodophyllotoxin VP-16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
 
Eposin, Vepesid, VP-16, Toposar, Etoposide
Etopol
Etopophos
Etopophos (phosphate salt)
Etoposid
Etoposide
Etoposide (JP15/USP/INN)
Etoposide (VP16)
Etoposide [USAN:INN:BAN:JAN]
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
HMS1569O13
HMS2052N05
HMS2089F14
HSDB 6517
I06-0248
KBioSS_002410
LS-1214
Lastet
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-003-983-431
MolPort-004-905-001
MolPort-004-955-161
NCGC00025056-02
NChemBio.2007.10-comp19
NK 171
NSC 141540
NSC-141540
NSC141540
Prestwick0_000396
Prestwick1_000396
Prestwick2_000396
Prestwick3_000396
Prestwick_211
S1225_Selleck
SAM001246880
SMR000112002
SPBio_002532
ST056353
Toposar
UNII-6PLQ3CP4P3
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16-213
VePESID (TN)
VePesid
Vepesid
Vepesid J
Vepeside
ZINC03830818
ZINC03938684
Zuyeyidal
etoposide
nchembio.573-comp8
nchembio873-comp2
trans-Etoposide
29
Cyclophosphamide275650-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
30
asparaginase2169015-68-3
Synonyms:
Asparaginase (E. coli)
 
Elspar
L-asparagine amidohydrolase
Putative L-asparaginase precursor
31Alkylating Agents4573
32
Doxorubicin167623214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
33
Cytarabine1074147-94-46253
Synonyms:
(beta-D-Arabinofuranosyl)cytosine
(beta-D-arabinofuranosyl)cytosine
1-.beta.-D-arabinofuranosyl-cytosine
1-Arabinofuranosylcytosine
1-beta -D-Arabinofaranosylcytosine
1-beta -D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta -D-Arabinofuranosylcytosine
1-beta-D-Arabinofaranosylcytosine
1-beta-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta-D-Arabinofuranosyl-Cytosine
1-beta-D-Arabinofuranosylcytosine
1-beta-D-Arabinofuranosylcytosine, Cytosine Arabinoside
1-beta-D-Arabinosyl-Cytosine
1-beta-D-Arabinosylcytosine
147-94-4
1beta -Arabinofuranasylcytosine
1beta -D-Arabinofuranosylcytosine
1beta -D-Arabinosylcytosine
1beta-Arabinofuranasylcytosine
1beta-D-Arabinofuranosylcytosine
1beta-D-Arabinosylcytosine
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl- [CAS]
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl
30399_FLUKA
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin [Czech]
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
4-Amino-1-b-D-arabinofuranosyl-2-(1H)-pyrimidinone
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon [Czech]
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
69-74-9 (hydrochloride)
AC-1075
AC1L1M4F
AC1Q52OJ
AI3-52329
AR3
Alexan
Ara-C
Ara-C, Cytosine Arabinoside, Cytosar-U, Cytarabine
Ara-Cytidine
AraC
Arabinocytidine
Arabinofuranosyl Cytidine
Arabinofuranosylcytosine
Arabinosyl Cytosine
Arabinosylcytosine
Arabitin
Aracytidine
Aracytin
Aracytine
Arafcyt
BIDD:GT0371
BIDD:PXR0139
BTB15125
Beta-cytosine arabinoside
C02961
C1768_SIGMA
C2035
C9H13N3O5
CCRIS 913
CHEBI:28680
CHEMBL803
CHX 3311
CID6253
CPD000449317
CYTARABINE (SEE ALSO CYTARABINE HYDROCHLORIDE 69-74-9)
Citarabina
Citarabina [INN-Spanish]
Cytarabin
Cytarabina
Cytarabine
Cytarabine (JP15/USP/INN)
 
Cytarabine [USAN:INN:BAN:JAN]
Cytarabine liposome injection
Cytarabinoside
Cytarabinum
Cytarabinum [INN-Latin]
Cytarbel
Cytonal
Cytosar
Cytosar-U
Cytosine 1-beta-D-arabinofuranoside
Cytosine arabinofuranoside
Cytosine arabinose
Cytosine arabinoside
Cytosine arabinoside (VAN)
Cytosine beta-D-arabinofuranoside
Cytosine beta-D-arabinofuranoside hydrochloride
Cytosine beta-D-arabinoside
Cytosine, beta -D-arabinoside
Cytosine, beta-D-arabinoside
Cytosine-1-beta-D-arabinofuranoside
Cytosine-1-beta-D-arabinofuranoside hydrochloride
Cytosine-beta -D-arabinofuranoside
Cytosine-beta -arabinoside
Cytosine-beta-D-arabinofuranoside
Cytosine-beta-arabinoside
Cytosinearabinoside
D00168
DB00987
DepoCyte
Depocyt
Depocyt (TN)
Depocyt (liposomal)
Depocyte
EINECS 205-705-9
Erpalfa
FT-0082880
HMS2051K19
HMS2090A18
HSDB 3049
Intrathecal (injected into the spinal fluid) DepoCyt
Intrathecal cytarabine (also known as ara-C)
Iretin
LS-860
Lopac0_000316
MLS000758310
MLS001066340
MolPort-001-792-509
NCGC00093356-03
NCGC00093356-04
NCGC00093356-05
NCI-C04728
NSC 287459
NSC287459
S1648_Selleck
SAM001247012
SMR000449317
SR-01000075773-3
Spongocytidine
TL8001048
Tarabine
U 19920A
U-19,920
U-19920
UNII-04079A1RDZ
Udicil
ZINC03795098
beta -D-arabinosylcytosine
beta -arabinosylcytosine
beta -cytosine arabinoside
beta-Ara C
beta-Ara c
beta-Arabinosylcytosine
beta-Cytosine arabinoside
beta-D-Arabinosylcytosine
cytarabine
cytarabine liposome injection
cytosine-β-D-arabinofuranoside
34
Daunorubicin25920830-81-330323
Synonyms:
(+)-Daunomycin
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside
(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
11006-54-5
11048-29-6
1407-15-4
149541-57-1
20830-81-3
23942-76-9
27576-81-4
28020-80-6
AB00514669
AC1L1JCP
AC1Q29OI
AI3-52942
Acetyladriamycin
Anthracyline
Antibiotics From Streptomyces Coeruleorubidus
Antibiotics from Streptomyces coeruleorubidus
BPBio1_000389
BRD-K43389675-003-02-7
BRN 1445583
BSPBio_000353
C01907
CCRIS 914
CHEBI:41977
CHEMBL178
CID30323
Cerubidin
Cerubidine
D07776
DAUNORUBICIN HCL
DB00694
DM1
Daunamycin
Daunarubicinum
Dauno-Rubidomycine
DaunoXome
DaunoXome (TN)
Daunoblastin
Daunoblastine
Daunomycin
 
Daunomycin Hydrochloride
Daunomycin, Hydrochloride
Daunorrubicina
Daunorubicin
Daunorubicin (INN)
Daunorubicin (liposomal)
Daunorubicin Hcl
Daunorubicin Hydrochloride
Daunorubicin [INN:BAN]
Daunorubicin, Hydrochloride
Daunorubicina
Daunorubicine
Daunorubicinum
Daunorubicinum [INN-Latin]
Daunoxome
EINECS 244-069-7
FI 6339
FI6339
HMS2089H04
HMS2091K06
HSDB 5095
LMPK13050002
LS-187381
LS-997
Leukaemomycin C
MolPort-002-533-961
NCGC00024246-05
NCGC00024246-06
NCGC00025173-01
NCI-C04693
NChemBio.2007.10-comp14
NSC 83142
NSC-82151
Ondena
Prestwick3_000487
RCRA waste no. U059
RP 13057
Rcra Waste No. U059
Rp 13057 Hydrochloride
Rubidomycin
Rubidomycin Hydrochloride
Rubomycin
Rubomycin C
Tocris-1467
UNII-ZS7284E0ZP
VS-103
daunorubicin
nchembio723-comp2
35
butyric acidPhase 0350107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
36
BaclofenPhase 0951134-47-02284
Synonyms:
( inverted question mark)-Baclofen
(+-)-Baclofen
(+/-)- beta-(Aminoethyl)-4- chlorobenzenepropanoic acid
(+/-)-BACLOFEN
(+/-)-beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
(?)-Baclofen
1134-47-0
4-Amino-3-(4-chlorophenyl)butanoic acid
4-Amino-3-(4-chlorophenyl)butyric acid
62594-36-9
AB00051921
AC-4530
AC1L1DC6
ASTA Medica Brand of Baclofen
AWD, Baclofen
Alphapharm Brand of Baclofen
Apo Baclofen
Apo-Baclofen
ApoBaclofen
Apotex Brand of Baclofen
Ashbourne Brand of Baclofen
Athena Brand of Baclofen
Atrofen
B 5399
B3343
B5399_SIGMA
BPBio1_000012
BPBio1_000750
BRD-A84174873-001-05-2
BRN 2104494
BSPBio_000010
BSPBio_001880
Ba 34647
Ba-34,647
Ba-34647
Ba34,647
Ba34647
Baclofen (JP15/USP/INN)
Baclofen (R,S)
Baclofen AWD
Baclofen Alphapharm Brand
Baclofen Apotex Brand
Baclofen Ashbourne Brand
Baclofen Athena Brand
Baclofen Ciba-Geigy Brand
Baclofen Irex Brand
Baclofen Isis Brand
Baclofen Medtronic Brand
Baclofen Novartis Brand
Baclofen Nu-Pharm Brand
Baclofen Pharmascience Brand
Baclofen [USAN:INN:BAN:JAN]
Baclofene
Baclofene Irex
Baclofene [INN-French]
Baclofene-Irex
BaclofeneIrex
Baclofeno
Baclofeno [INN-Spanish]
Baclofenum
Baclofenum [INN-Latin]
Baclon
Baclophen
Baclospas
Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-(9CI)
Biomol-NT_000251
C 34647Ba
C10H12ClNO2
CCRIS 3722
CHEBI:2972
CHEMBL701
CIBA-34,647-BA
CIBA34,647BA
CID2284
Chlorophenyl GABA
Ciba 34,647-Ba
Ciba Geigy Brand of Baclofen
Ciba-Geigy Brand of Baclofen
Clofen
D001418
D00241
DB00181
DL-4-Amino-3-P-chlorophenylbutanoic acid
DL-4-Amino-3-p-chlorophenylbutanoic acid
DL-Baclofen
 
DivK1c_000001
EINECS 214-486-9
EU-0100163
GABA, Chlorophenyl
Gabalon
Gen Baclofen
Gen-Baclofen
GenBaclofen
Genpharm
HMS1568A12
HMS1920E21
HMS2091M03
HMS500A03
I01-1934
IDI1_000001
Irex Brand of Baclofen
Isis Brand of Baclofen
KBio1_000001
KBio2_000466
KBio2_003034
KBio2_005602
KBio3_001380
KBioGR_000650
KBioSS_000466
Kemstro
Kemstro (TN)
L000002
LS-77134
Lebic
Lioresal
Lioresal (TN)
Lioresal Intrathecal
Lopac0_000163
MLS000028480
Medtronic Brand of Baclofen
MolPort-002-051-370
NCGC00015156-05
NCGC00015156-12
NCGC00023843-03
NCGC00024579-03
NCGC00024579-04
NCGC00024579-05
NCGC00024579-06
NINDS_000001
NSC329137
Novartis Brand of Baclofen
Nu Baclo
Nu Pharm Brand of Baclofen
Nu-Baclo
Nu-Baclofen
Nu-Pharm Brand of Baclofen
NuBaclo
Oprea1_440627
PCP-GABA
PMS Baclofen
PMSBaclofen
Pharmascience Brand of Baclofen
Pms-Baclofen
Prestwick0_000085
Prestwick1_000085
Prestwick2_000085
Prestwick3_000085
Prestwick_85
SMP1_000036
SMR000058294
SPBio_000044
SPBio_001949
SPECTRUM1500135
STK535284
STOCK2S-30552
Spectrum2_000092
Spectrum3_000310
Spectrum4_000245
Spectrum5_000852
Spectrum_000066
UNII-H789N3FKE8
UPCMLD-DP142
UPCMLD-DP142:001
baclofen
beta-(4-Chlorophenyl)gaba
beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
beta-(Aminomethyl)-P-chlorohydrocinnamic acid
beta-(Aminomethyl)-p-chlorohydrocinnamic acid
beta-(P-Chlorophenyl)-gamma-aminobutyric acid
beta-(p-Chlorophenyl)-gamma-aminobutyric acid
gamma-Amino-beta-(P-chlorophenyl)butyric acid
gamma-Amino-beta-(p-chlorophenyl)butyric acid
37FolateNutraceutical4143
38
Folic AcidNutraceutical414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10

Interventional clinical trials:

(show all 24)
idNameStatusNCT IDPhase
1Amantadine for Improving Neurologic Symptoms in Ataxia-TelangiectasiaCompletedNCT00950196Phase 4
2Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)RecruitingNCT01052623Phase 4
3Response of Individuals With Ataxia-Telangiectasia to Metformin and PioglitazoneNot yet recruitingNCT02733679Phase 4
4Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)CompletedNCT00656409Phase 3
5EDS in Ataxia Telangiectasia PatientsNot yet recruitingNCT02770807Phase 3
6Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell TransplantCompletedNCT00110045Phase 2
7Gemcitabine Hydrochloride Alone or With VX-970 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerRecruitingNCT02595892Phase 2
8Efficacy Study of Olaparib With Paclitaxel Versus Paclitaxel in Gastric Cancer PatientsActive, not recruitingNCT01063517Phase 2
9A Study of MK-4827 for the Treatment of Mantle Cell Lymphoma (MK-4827-002)WithdrawnNCT01244009Phase 2
10VX-970 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryRecruitingNCT02595931Phase 1
11Study of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory CancerRecruitingNCT02630199Phase 1
12Body Composition and Hormonal Status in Ataxia TelangiectasiaCompletedNCT02345200
13Study for Treatment of Cancer in Children With Ataxia-telangiectasiaCompletedNCT00187057
14International Ataxia Rating Scale in Younger PatientsCompletedNCT01942850
15Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-TRecruitingNCT02285348
16Cell-Based Approaches For Modeling and Treating Ataxia-TelangiectasiaRecruitingNCT02246491
17Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated)RecruitingNCT02857894
18Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
19Pancreatic Cancer Screening of High-Risk Individuals in ArkansasRecruitingNCT02309632
20Development of iPS From Donated Somatic Cells of Patients With Neurological DiseasesRecruitingNCT00874783
21Baclofen Treatment of Ataxia TelangiectasiaActive, not recruitingNCT00640003Phase 0
22The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied LongitudinallyActive, not recruitingNCT00951886
23Susceptibility to Infections in Ataxia TelangiectasiaEnrolling by invitationNCT02345135
24Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia PatientsNot yet recruitingNCT01075438

Search NIH Clinical Center for Ataxia-Telangiectasia

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Ataxia-Telangiectasia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Ataxia-Telangiectasia:
Renexus
Embryonic/Adult Cultured Cells Related to Ataxia-Telangiectasia:
Human retinal stem cells secreting CNTF, PMIDs: 16805711, 17508034, 16505355, 23049090, 15684670, 12581701, 15223826, 18830926


Cochrane evidence based reviews: ataxia telangiectasia

Genetic Tests for Ataxia-Telangiectasia

About this section

Genetic tests related to Ataxia-Telangiectasia:

id Genetic test Affiliating Genes
1 Ataxia-Telangiectasia Syndrome25
2 Ataxia-Telangiectasia Variant25
3 Ataxia-Telangiectasia23 ATM

Anatomical Context for Ataxia-Telangiectasia

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MalaCards organs/tissues related to Ataxia-Telangiectasia:

34
Eye, Skin, Brain, Lung, Breast, T cells, B cells

Animal Models for Ataxia-Telangiectasia or affiliated genes

About this section

MGI Mouse Phenotypes related to Ataxia-Telangiectasia:

39 (show all 27)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000118610.1ATR, BRCA1, PRKDC, RAD50, TP53
2MP:00107719.4ATM, ATR, BRCA1, CDKN1A, CHEK1, PRKDC
3MP:00053759.3AGTR1, ATM, ATR, BRCA1, CDKN1A, PCNA
4MP:00053809.1ATM, ATR, BRCA1, CDKN1A, CHEK1, MRE11A
5MP:00053868.8AGTR1, ATM, ATR, BRCA1, CDKN1A, MRE11A
6MP:00053898.3ATM, ATR, BRCA1, CDKN1A, CHEK1, H2AFX
7MP:00020068.3ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
8MP:00053788.1AGTR1, ATM, ATR, BRCA1, CDKN1A, H2AFX
9MP:00053878.0AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK2
10MP:00053768.0AGTR1, APTX, ATM, ATR, BRCA1, CDKN1A
11MP:00053977.9AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK2
12MP:00053797.9ATM, ATR, BRCA1, CDKN1A, CHEK1, DCLRE1C
13MP:00053847.8APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1
14MP:00107687.6AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK1

Publications for Ataxia-Telangiectasia

About this section

Articles related to Ataxia-Telangiectasia:

(show top 50)    (show all 837)
idTitleAuthorsYear
1
Serum Interleukin-6 Levels and Pulmonary Function inA Ataxia-Telangiectasia. (26851119)
2016
2
Analysis of Residual DSBs in Ataxia-Telangiectasia Lymphoblast Cells Initiating Apoptosis. (27057549)
2016
3
Molecular and Functional Characterization of a Cohort of Spanish Patients with Ataxia-Telangiectasia. (27664052)
2016
4
Primary Diffuse Large B-cell Lymphoma Arising in the Tongue Accompanied by Ataxia-telangiectasia: A Case Report. (26266230)
2015
5
Multi-drugs resistant acne rosacea in a child affected by Ataxia-Telangiectasia: successful treatment with Isotretinoin. (25881033)
2015
6
Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia. (26469940)
2015
7
Altered corticomotor-cerebellar integrity in young ataxia telangiectasia patients. (25042086)
2014
8
Twelve novel Atm mutations identified in Chinese ataxia telangiectasia patients. (23807571)
2013
9
The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia. (23502677)
2013
10
Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia. (22006793)
2012
11
Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study. (22213089)
2012
12
Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. (21321203)
2011
13
Ataxia telangiectasia: A report of two cousins and review of literature. (22563157)
2011
14
Ataxia telangiectasia and Rad3-related overexpressing cancer cells induce prolonged Ga88 arrest and develop resistance to ionizing radiation. (21294646)
2011
15
Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours. (21792198)
2011
16
Ataxia telangiectasia: Family management. (20838492)
2010
17
A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells. (20947454)
2010
18
Update on the management of the immunodeficiency in ataxia-telangiectasia. (20477642)
2009
19
Syndrome of premature ageing in ataxia-telangiectasia patients]. (19799357)
2009
20
Hemorrhagic cystitis in a child with Hodgkin lymphoma and ataxia-telangiectasia after cyclophosphamide. (19418546)
2009
21
Prognostic significance of ataxia-telangiectasia mutated, DNA-dependent protein kinase catalytic subunit, and Ku heterodimeric regulatory complex 86-kD subunit expression in patients with nonsmall cell lung cancer. (18457328)
2008
22
Ataxia-telangiectasia mutated expression is associated with tobacco smoke exposure in esophageal cancer tissues and benzo[a]pyrene diol epoxide in cell lines. (17019709)
2007
23
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. (17478428)
2007
24
Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection. (16952553)
2006
25
Modifications of nuclear architecture and chromatin organization in ataxia telangiectasia cells are coupled to changes of gene transcription. (16795050)
2006
26
Exclusion/confirmation of ataxia-telangiectasia via cell-cycle testing. (16411093)
2006
27
Mutation analysis of the ATM gene in two Chinese patients with ataxia telangiectasia. (16380133)
2006
28
Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation. (17178844)
2006
29
Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression. (16636671)
2006
30
Molecular basis of ataxia telangiectasia and related diseases. (16038621)
2005
31
Molecular pathology of ataxia telangiectasia. (16189143)
2005
32
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. (15510216)
2004
33
A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells. (11744712)
2002
34
Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting. (11839094)
2002
35
Spontaneous and oxidative stress-induced programmed cell death in lymphocytes from patients with ataxia telangiectasia (AT). (10606975)
2000
36
Efficient DNA base excision repair in ataxia telangiectasia cells. (11082200)
2000
37
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. (10500142)
1999
38
Ataxia-telangiectasia in the Japanese population: identification of R1917X, W2491R, R2909G, IVS33+2T-->A, and 7883del5, the latter two being relatively common mutations. (9792410)
1998
39
ATM mutations in patients with ataxia telangiectasia screened by a hierarchical strategy. (9711876)
1998
40
Diagnosis of ataxia telangiectasia with the glycophorin A somatic mutation assay. (10464655)
1997-1998
41
G2 chromosomal radiosensitivity in fibroblasts of ataxia-telangiectasia heterozygotes and a Li-Fraumeni syndrome patient with radioresistant cells. (9343108)
1997
42
An unusual case of urinary incontinence, ataxia-telangiectasia, and metastatic dysgerminoma: case report and review of the literature. (9301718)
1997
43
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. (9168116)
1997
44
Rapamycin resistance in ataxia-telangiectasia. (8806686)
1996
45
The ataxia-telangiectasia-variant genes 1 and 2 are distinct from the ataxia-telangiectasia gene on chromosome 11q23.1. (7573059)
1995
46
An early-onset recessive cerebellar disorder with distal amyotrophy and, in two patients, gross myoclonia: a probable ataxia telangiectasia variant. (7788963)
1995
47
Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene. (7923077)
1994
48
Cloning efficiency and spontaneous mutant frequency in circulating T-lymphocytes in ataxia-telangiectasia patients. (7836839)
1994
49
Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. (8247533)
1993
50
Diabetes mellitus in ataxia-telangiectasia, Fanconi anemia, xeroderma pigmentosum, common variable immune deficiency, and severe combined immune deficiency families. (3943665)
1986

Variations for Ataxia-Telangiectasia

About this section

UniProtKB/Swiss-Prot genetic disease variations for Ataxia-Telangiectasia:

68 (show all 39)
id Symbol AA change Variation ID SNP ID
1ATMp.Lys224GluVAR_010801
2ATMp.Pro292LeuVAR_010802
3ATMp.Ile323ValVAR_010803
4ATMp.Phe570SerVAR_010808
5ATMp.Asn768AspVAR_010812
6ATMp.Arg785CysVAR_010813
7ATMp.Leu950ArgVAR_010815
8ATMp.Leu1001GlnVAR_010816
9ATMp.His1082LeuVAR_010819
10ATMp.Glu1091AspVAR_010820
11ATMp.Leu1420ProVAR_010823
12ATMp.Leu1465ProVAR_010826
13ATMp.Pro1566ArgVAR_010827
14ATMp.Thr1743IleVAR_010831
15ATMp.Val1913GlyVAR_010836
16ATMp.Asp2016GlyVAR_010838
17ATMp.Gly2063GluVAR_010839
18ATMp.Ala2067AspVAR_010840
19ATMp.Ser2218CysVAR_010844
20ATMp.Arg2227CysVAR_010846
21ATMp.Val2424GlyVAR_010854
22ATMp.Tyr2470AspVAR_010858
23ATMp.Trp2491ArgVAR_010860
24ATMp.His2554AspVAR_010862
25ATMp.Asp2625GlnVAR_010863
26ATMp.Leu2656ProVAR_010865
27ATMp.Glu2668GlyVAR_010868
28ATMp.Ile2702ArgVAR_010870
29ATMp.Ala2726ValVAR_010874
30ATMp.Cys2824TyrVAR_010878
31ATMp.Phe2827CysVAR_010879
32ATMp.Pro2829LeuVAR_010880
33ATMp.Arg2832CysVAR_010881
34ATMp.Arg2849ProVAR_010882
35ATMp.Ser2855ArgVAR_010883
36ATMp.Gly2867ArgVAR_010886
37ATMp.Glu2904GlyVAR_010889
38ATMp.Arg2909GlyVAR_010890
39ATMp.Arg3008CysVAR_010893

Clinvar genetic disease variations for Ataxia-Telangiectasia:

5 (show all 147)
id Gene Variation Type Significance SNP ID Assembly Location
1ATMNM_000051.3(ATM): c.1339C> T (p.Arg447Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587779815GRCh38Chr 11, 108250804: 108250804
2ATMNM_000051.3(ATM): c.1564_1565delGA (p.Glu522Ilefs)deletionPathogenicrs587779817GRCh38Chr 11, 108251029: 108251030
3ATMNM_000051.3(ATM): c.170G> A (p.Trp57Ter)single nucleotide variantPathogenicrs587779818GRCh38Chr 11, 108227873: 108227873
4ATMNM_000051.3(ATM): c.3372C> G (p.Tyr1124Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587779833GRCh38Chr 11, 108279578: 108279578
5ATMNM_000051.3(ATM): c.3802delG (p.Val1268Terfs)deletionPathogenicrs587779834GRCh38Chr 11, 108284282: 108284282
6ATMNM_000051.3(ATM): c.5228C> T (p.Thr1743Ile)single nucleotide variantLikely pathogenicrs587779844GRCh38Chr 11, 108301698: 108301698
7ATMNM_000051.3(ATM): c.5290delC (p.Leu1764Tyrfs)deletionLikely pathogenic, Pathogenicrs587779846GRCh38Chr 11, 108301760: 108301760
8NM_000051.3(ATM): c.5932G> T (p.Glu1978Ter)single nucleotide variantPathogenicrs587779852GRCh38Chr 11, 108312424: 108312424
9NM_000051.3(ATM): c.6100C> T (p.Arg2034Ter)single nucleotide variantLikely pathogenic, Pathogenicrs532480170GRCh38Chr 11, 108316015: 108316015
10NM_000051.3(ATM): c.7630-2A> Csingle nucleotide variantPathogenicrs587779866GRCh38Chr 11, 108331877: 108331877
11NM_000051.3(ATM): c.8494C> T (p.Arg2832Cys)single nucleotide variantLikely pathogenic, Pathogenicrs587779872GRCh38Chr 11, 108345818: 108345818
12NM_000051.3(ATM): c.8786+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs17174393GRCh38Chr 11, 108353881: 108353881
13ATMNM_000051.3(ATM): c.5652dupA (p.Thr1885Asnfs)duplicationPathogenicrs587778077GRCh37Chr 11, 108175557: 108175557
14ATMNM_000051.3(ATM): c.1027_1030delGAAAdeletionLikely pathogenic, Pathogenicrs587780612GRCh38Chr 11, 108247089: 108247092
15NM_000051.3(ATM): c.7788G> A (p.Glu2596=)single nucleotide variantPathogenicrs587780639GRCh38Chr 11, 108332037: 108332037
16NM_000051.3(ATM): c.8266A> T (p.Lys2756Ter)single nucleotide variantLikely pathogenic, Pathogenicrs371638537GRCh38Chr 11, 108335959: 108335959
17NM_000051.3(ATM): c.9079dupA (p.Ser3027Lysfs)duplicationLikely pathogenic, Pathogenicrs587780645GRCh38Chr 11, 108365416: 108365416
18NM_000051.3(ATM): c.6997dupA (p.Thr2333Asnfs)duplicationPathogenicrs587781299GRCh37Chr 11, 108198393: 108198393
19ATMNM_000051.3(ATM): c.1402_1403delAA (p.Lys468Glufs)deletionLikely pathogenic, Pathogenicrs587781347GRCh37Chr 11, 108121594: 108121595
20ATMNM_000051.3(ATM): c.2921+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs587781558GRCh37Chr 11, 108141874: 108141874
21NM_000051.3(ATM): c.7913G> A (p.Trp2638Ter)single nucleotide variantLikely pathogenic, Pathogenicrs377349459GRCh37Chr 11, 108203613: 108203613
22ATMNM_000051.3(ATM): c.2284_2285delCT (p.Leu762Valfs)deletionPathogenicrs587781658GRCh37Chr 11, 108128241: 108128242
23NM_000051.3(ATM): c.7096G> T (p.Glu2366Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587781672GRCh37Chr 11, 108199754: 108199754
24NM_000051.3(ATM): c.5908C> T (p.Gln1970Ter)single nucleotide variantPathogenicrs587781722GRCh37Chr 11, 108181032: 108181032
25NM_000051.3(ATM): c.5712dupA (p.Ser1905Ilefs)duplicationLikely pathogenic, Pathogenicrs587781730GRCh37Chr 11, 108178661: 108178661
26ATMNM_000051.3(ATM): c.3993+1G> Asingle nucleotide variantPathogenicrs200196781GRCh37Chr 11, 108155201: 108155201
27ATMNM_000051.3(ATM): c.3894dupT (p.Ala1299Cysfs)duplicationPathogenicrs587781823GRCh37Chr 11, 108155101: 108155101
28NM_000051.3(ATM): c.9023G> A (p.Arg3008His)single nucleotide variantLikely pathogenicrs587781894GRCh38Chr 11, 108365360: 108365360
29ATMNM_000051.3(ATM): c.4776+2T> Csingle nucleotide variantPathogenicrs587781927GRCh37Chr 11, 108164206: 108164206
30ATMNM_000051.3(ATM): c.4198A> T (p.Lys1400Ter)single nucleotide variantPathogenicrs587781950GRCh38Chr 11, 108289065: 108289065
31ATMNM_000051.3(ATM): c.790delT (p.Tyr264Ilefs)deletionPathogenicrs587781978GRCh37Chr 11, 108115642: 108115642
32ATMNM_000051.3(ATM): c.2921+1G> Tsingle nucleotide variantLikely pathogenic, Pathogenicrs587781558GRCh37Chr 11, 108141874: 108141874
33ATMNM_000051.3(ATM): c.3994-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs587782276GRCh37Chr 11, 108158325: 108158325
34NM_000051.3(ATM): c.9022C> T (p.Arg3008Cys)single nucleotide variantLikely pathogenic, Pathogenicrs587782292GRCh38Chr 11, 108365359: 108365359
35ATMNM_000051.3(ATM): c.1110C> G (p.Tyr370Ter)single nucleotide variantPathogenicrs376170600GRCh37Chr 11, 108119704: 108119704
36NM_000051.3(ATM): c.6976-2A> Csingle nucleotide variantLikely pathogenic, Pathogenicrs587782403GRCh37Chr 11, 108198370: 108198370
37NM_000051.3(ATM): c.8432delA (p.Lys2811Serfs)deletionPathogenicrs587782558GRCh38Chr 11, 108345756: 108345756
38NM_000051.3(ATM): c.8147T> C (p.Val2716Ala)single nucleotide variantLikely pathogenic, Pathogenicrs587782652GRCh38Chr 11, 108335105: 108335105
39NM_000051.3(ATM): c.8264_8268delATAAG (p.Tyr2755Cysfs)deletionPathogenicrs730881294GRCh38Chr 11, 108335957: 108335961
40NM_000051.3(ATM): c.8418+5_8418+8delGTGAdeletionPathogenicrs730881295GRCh38Chr 11, 108343376: 108343379
41ATMNM_000051.3(ATM): c.368delA (p.Tyr123Leufs)deletionPathogenicrs730881296GRCh38Chr 11, 108235706: 108235706
42ATMNM_000051.3(ATM): c.5320-5_5320-2delTCTAdeletionLikely pathogenic, Pathogenicrs730881310GRCh38Chr 11, 108302848: 108302851
43ATMNM_000051.3(ATM): c.2251-10T> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs730881346GRCh38Chr 11, 108257471: 108257471
44ATMNM_000051.3(ATM): c.3154-2A> Gsingle nucleotide variantPathogenicrs730881357GRCh38Chr 11, 108272720: 108272720
45NM_000051.3(ATM): c.6095G> A (p.Arg2032Lys)single nucleotide variantLikely pathogenic, Pathogenicrs139770721GRCh38Chr 11, 108315911: 108315911
46NM_000051.3(ATM): c.6154G> A (p.Glu2052Lys)single nucleotide variantLikely pathogenicrs202206540GRCh38Chr 11, 108316069: 108316069
47NM_000051.3(ATM): c.6679C> T (p.Arg2227Cys)single nucleotide variantLikely pathogenic, Pathogenicrs564652222GRCh38Chr 11, 108325416: 108325416
48ATMNM_000051.3(ATM): c.4394T> C (p.Leu1465Pro)single nucleotide variantLikely pathogenicrs730881391GRCh38Chr 11, 108289759: 108289759
49NM_000051.3(ATM): c.5890A> T (p.Lys1964Ter)single nucleotide variantLikely pathogenic, Pathogenicrs201963507GRCh38Chr 11, 108310287: 108310287
50ATMNM_000051.3(ATM): c.478_482delTCTCA (p.Ser160Alafs)deletionPathogenicrs587780624GRCh37Chr 11, 108106543: 108106547
51ATMNM_000051.3(ATM): c.4052delT (p.Leu1351Tyrfs)deletionPathogenicrs786202350GRCh37Chr 11, 108158385: 108158385
52NM_000051.3(ATM): c.8036_8051del16 (p.Asn2679Serfs)deletionPathogenicrs587780640GRCh37Chr 11, 108205721: 108205736
53ATMNM_000051.3(ATM): c.2720_2723delGTGT (p.Cys907Terfs)deletionPathogenicrs786202695GRCh37Chr 11, 108139218: 108139221
54NM_000051.3(ATM): c.8395_8404delTTTCAGTGCC (p.Phe2799Lysfs)deletionPathogenicrs786202800GRCh37Chr 11, 108214075: 108214084
55NM_000051.3(ATM): c.8711A> G (p.Glu2904Gly)single nucleotide variantLikely pathogenicrs786202826GRCh37Chr 11, 108224532: 108224532
56NM_000051.3(ATM): c.8977C> T (p.Arg2993Ter)single nucleotide variantLikely pathogenic, Pathogenicrs770641163GRCh37Chr 11, 108235935: 108235935
57NM_000051.3(ATM): c.8293G> A (p.Gly2765Ser)single nucleotide variantLikely pathogenicrs748634900GRCh37Chr 11, 108213973: 108213973
58NM_000051.3(ATM): c.6228delT (p.Leu2077Phefs)deletionPathogenicrs786203008GRCh37Chr 11, 108188129: 108188129
59ATMNM_000051.3(ATM): c.901+1G> Asingle nucleotide variantPathogenicrs748840480GRCh37Chr 11, 108115754: 108115754
60NM_000051.3(ATM): c.7000_7003delTACA (p.Tyr2334Glnfs)deletionPathogenicrs786203421GRCh37Chr 11, 108198396: 108198399
61NM_000051.3(ATM): c.8786+1G> Csingle nucleotide variantPathogenicrs17174393GRCh37Chr 11, 108224608: 108224608
62ATMNM_000051.3(ATM): c.2T> C (p.Met1Thr)single nucleotide variantLikely pathogenic, Pathogenicrs786203606GRCh37Chr 11, 108098353: 108098353
63ATMNM_000051.3(ATM): c.2921+1G> Csingle nucleotide variantLikely pathogenic, Pathogenicrs587781558GRCh38Chr 11, 108271147: 108271147
64NM_000051.3(ATM): c.8851-?_*(1_?)deldeletionPathogenicGRCh38Chr 11, 108365082: 108365509
65ATMNM_000051.3(ATM): c.72+1G> Asingle nucleotide variantLikely pathogenicrs786204088GRCh38Chr 11, 108227697: 108227697
66ATMNM_000051.3(ATM): c.5644C> T (p.Arg1882Ter)single nucleotide variantLikely pathogenic, Pathogenicrs786204433GRCh37Chr 11, 108175549: 108175549
67NM_000051.3(ATM): c.7927+5delGdeletionLikely pathogenicrs786204437GRCh37Chr 11, 108203632: 108203632
68ATMNM_000051.3(ATM): c.640delT (p.Ser214Profs)deletionLikely pathogenicrs786204543GRCh38Chr 11, 108244096: 108244096
69ATMNM_000051.3(ATM): c.3G> A (p.Met1Ile)single nucleotide variantLikely pathogenic, Pathogenicrs781404312GRCh38Chr 11, 108227627: 108227627
70ATMNM_000051.3(ATM): c.802C> T (p.Gln268Ter)single nucleotide variantLikely pathogenic, Pathogenicrs557012154GRCh38Chr 11, 108244927: 108244927
71ATMNM_000051.3(ATM): c.5188C> T (p.Arg1730Ter)single nucleotide variantLikely pathogenic, Pathogenicrs764389018GRCh38Chr 11, 108301658: 108301658
72NM_000051.3(ATM): c.8307G> A (p.Trp2769Ter)single nucleotide variantLikely pathogenic, Pathogenicrs778269655GRCh38Chr 11, 108343260: 108343260
73NM_000051.3(ATM): c.8876_8879delACTG (p.Asp2959Glyfs)deletionLikely pathogenic, Pathogenicrs786204726GRCh37Chr 11, 108235834: 108235837
74ATMNM_000051.3(ATM): c.1524delT (p.Gly509Glufs)deletionLikely pathogenicrs786204737GRCh38Chr 11, 108250989: 108250989
75ATMNM_000051.3(ATM): c.5515C> T (p.Gln1839Ter)single nucleotide variantLikely pathogenicrs786204751GRCh38Chr 11, 108304693: 108304693
76ATMNM_000051.3(ATM): c.4111delG (p.Asp1371Ilefs)deletionLikely pathogenic, Pathogenicrs797045114GRCh37Chr 11, 108159705: 108159705
77NM_000051.3(ATM): c.6049dupA (p.Ser2017Lysfs)duplicationPathogenicrs797045030GRCh37Chr 11, 108186592: 108186592
78NM_000051.3(ATM): c.7926A> C (p.Arg2642Ser)single nucleotide variantLikely pathogenicrs863224440GRCh38Chr 11, 108332899: 108332899
79ATMNM_000051.3(ATM): c.1284_1291delTAACTGTG (p.Asn429Alafs)deletionPathogenicrs863224460GRCh38Chr 11, 108250749: 108250756
80ATMNM_000051.3(ATM): c.140C> G (p.Ser47Ter)single nucleotide variantPathogenicrs774185390GRCh38Chr 11, 108227843: 108227843
81ATMNM_000051.3(ATM): c.2413C> T (p.Arg805Ter)single nucleotide variantPathogenicrs780619951GRCh38Chr 11, 108259022: 108259022
82NM_000051.3(ATM): c.6750_6751insCTCA (p.Lys2253Hisfs)insertionPathogenicrs863224461GRCh37Chr 11, 108196214: 108196215
83NM_000051.3(ATM): c.7240C> T (p.Gln2414Ter)single nucleotide variantPathogenicrs863224462GRCh37Chr 11, 108199898: 108199898
84ATMNM_000051.3(ATM): c.748C> T (p.Arg250Ter)single nucleotide variantPathogenicrs772821016GRCh37Chr 11, 108115600: 108115600
85NM_000051.3(ATM): c.7985T> A (p.Val2662Asp)single nucleotide variantPathogenicrs863224463GRCh37Chr 11, 108204670: 108204670
86ATMNM_000051.3(ATM): c.2113delT (p.Tyr705Thrfs)deletionPathogenicrs863224822GRCh38Chr 11, 108254028: 108254028
87NM_000051.3(ATM): c.6415_6416delGA (p.Glu2139Ilefs)deletionLikely pathogenic, Pathogenicrs863225466GRCh38Chr 11, 108320021: 108320022
88ATMNM_000051.3(ATM): c.3284+1G> Asingle nucleotide variantLikely pathogenicrs864622129GRCh38Chr 11, 108272853: 108272853
89ATMNM_000051.3(ATM): c.785T> A (p.Leu262Ter)single nucleotide variantPathogenicrs864622163GRCh38Chr 11, 108244910: 108244910
90ATMNM_000051.3(ATM): c.4736dupA (p.Ile1581Asnfs)duplicationPathogenicrs864622164GRCh37Chr 11, 108164164: 108164164
91NM_000051.3(ATM): c.8988-1G> Asingle nucleotide variantLikely pathogenicrs730881386GRCh38Chr 11, 108365324: 108365324
92NM_000051.3(ATM): c.7789-3T> Gsingle nucleotide variantPathogenicrs864622185GRCh38Chr 11, 108332759: 108332759
93ATMNM_000051.3(ATM): c.4804_4805delGT (p.Val1602Leufs)deletionPathogenicrs864622290GRCh38Chr 11, 108294954: 108294955
94NM_000051.3(ATM): c.3403-?_*(1_?)deldeletionPathogenicGRCh38Chr 11, 108280995: 108365509
95NM_000051.3(ATM): c.6650_6657delTTAGTTTT (p.Phe2217Serfs)deletionPathogenicrs864622326GRCh38Chr 11, 108325387: 108325394
96ATMNM_000051.3(ATM): c.1369C> T (p.Arg457Ter)single nucleotide variantPathogenicrs749036865GRCh38Chr 11, 108250834: 108250834
97ATMNM_000051.3(ATM): c.3077+1G> Asingle nucleotide variantLikely pathogenicrs192810283GRCh38Chr 11, 108271407: 108271407
98NM_000051.3(ATM): c.6348-2A> Gsingle nucleotide variantLikely pathogenicrs864622367GRCh38Chr 11, 108319952: 108319952
99ATMNM_000051.3(ATM): c.824delT (p.Leu275Terfs)deletionPathogenicrs864622389GRCh38Chr 11, 108244949: 108244949
100ATMNM_000051.3(ATM): c.185+1G> Asingle nucleotide variantLikely pathogenicrs112805604GRCh37Chr 11, 108098616: 108098616
101ATMNM_000051.3(ATM): c.1914_1929dup16 (p.Ser644Argfs)duplicationPathogenicrs864622415GRCh38Chr 11, 108253829: 108253844
102NM_000051.3(ATM): c.7010_7011delGT (p.Cys2337Serfs)deletionPathogenicrs864622416GRCh37Chr 11, 108198406: 108198407
103ATMNM_000051.3(ATM): c.4588G> T (p.Glu1530Ter)single nucleotide variantPathogenicrs864622479GRCh38Chr 11, 108292770: 108292770
104ATMNM_000051.3(ATM): c.3663G> A (p.Trp1221Ter)single nucleotide variantPathogenicrs864622490GRCh37Chr 11, 108153523: 108153523
105NM_000051.3(ATM): c.7705_7706delGA (p.Asp2569Terfs)deletionPathogenicrs759965045GRCh38Chr 11, 108331954: 108331955
106ATMNM_000051.3(ATM): c.1607+1G> Tsingle nucleotide variantPathogenicrs772926890GRCh38Chr 11, 108251073: 108251073
107NM_000051.3(ATM): c.7928-2A> Tsingle nucleotide variantLikely pathogenicrs864622610GRCh37Chr 11, 108204611: 108204611
108NM_000051.3(ATM): c.6404_6405insTT (p.Arg2136Terfs)insertionPathogenicrs864622649GRCh37Chr 11, 108190737: 108190738
109ATMNM_000051.3(ATM): c.5015delG (p.Gly1672Glufs)deletionPathogenicrs864622662GRCh38Chr 11, 108299723: 108299723
110NM_000051.3(ATM): c.8873_8874delTT (p.Phe2958Terfs)deletionPathogenicrs864622669GRCh38Chr 11, 108365104: 108365105
111ATMNM_000051.3(ATM): c.4735C> T (p.Gln1579Ter)single nucleotide variantLikely pathogenic, Pathogenicrs869312755GRCh38Chr 11, 108293436: 108293436
112NM_000051.3(ATM): c.5762+1G> Tsingle nucleotide variantLikely pathogenicrs869312756GRCh37Chr 11, 108178712: 108178712
113ATMNM_000051.3(ATM): c.2455T> C (p.Cys819Arg)single nucleotide variantLikely pathogenicrs775644968GRCh37Chr 11, 108129791: 108129791
114ATMNM_000051.3(ATM): c.4098_4099delTG (p.Cys1366Terfs)deletionPathogenicrs876658248GRCh37Chr 11, 108158431: 108158432
115NM_000051.3(ATM): c.7886_7890delTATTA (p.Ile2629Serfs)deletionPathogenicrs587776548GRCh37Chr 11, 108203586: 108203590
116NM_000051.3(ATM): c.7088delA (p.Lys2363Argfs)deletionPathogenicrs876658512GRCh37Chr 11, 108198484: 108198484
117NM_000051.3(ATM): c.9019G> T (p.Glu3007Ter)single nucleotide variantLikely pathogenic, Pathogenicrs876660382GRCh37Chr 11, 108236083: 108236083
118ATMNM_000051.3(ATM): c.1240C> T (p.Gln414Ter)single nucleotide variantPathogenicrs866521873GRCh38Chr 11, 108250705: 108250705
119ATMNM_000051.3(ATM): c.192delA (p.Leu64Phefs)deletionPathogenicrs878853490GRCh37Chr 11, 108099911: 108099911
120ATMNM_000051.3(ATM): c.2466+2T> Asingle nucleotide variantLikely pathogenicrs878853495GRCh38Chr 11, 108259077: 108259077
121ATMNM_000051.3(ATM): c.289delA (p.Ile97Serfs)deletionPathogenicrs878853497GRCh38Chr 11, 108229281: 108229281
122ATMNM_000051.3(ATM): c.4396C> T (p.Arg1466Ter)single nucleotide variantPathogenicrs730881369GRCh38Chr 11, 108289761: 108289761
123ATMNM_000051.3(ATM): c.5203dupA (p.Thr1735Asnfs)duplicationPathogenicrs878853518GRCh37Chr 11, 108172400: 108172400
124ATMNM_000051.3(ATM): c.5443delG (p.Asp1815Thrfs)deletionPathogenicrs878853522GRCh37Chr 11, 108173703: 108173703
125ATMNM_000051.3(ATM): c.5549T> A (p.Leu1850Ter)single nucleotide variantPathogenicrs878853525GRCh37Chr 11, 108175454: 108175454
126NM_000051.3(ATM): c.6239_6240delAT (p.Tyr2080Phefs)deletionPathogenicrs878853529GRCh37Chr 11, 108188140: 108188141
127NM_000051.3(ATM): c.6373delC (p.His2125Metfs)deletionPathogenicrs878853530GRCh37Chr 11, 108190706: 108190706
128NM_000051.3(ATM): c.6667delA (p.Ile2223Serfs)deletionPathogenicrs878853533GRCh37Chr 11, 108196131: 108196131
129NM_000051.3(ATM): c.6916_6917delAG (p.Leu2307Cysfs)deletionPathogenicrs878853535GRCh38Chr 11, 108326166: 108326167
130NM_000051.3(ATM): c.7091delC (p.Ala2364Glufs)deletionPathogenicrs878853538GRCh37Chr 11, 108199749: 108199749
131NM_000051.3(ATM): c.7563C> G (p.Tyr2521Ter)single nucleotide variantPathogenicrs772228129GRCh37Chr 11, 108202218: 108202218
132ATMNM_000051.3(ATM): c.8851-?_*3591+?deldeletionPathogenic
133ATMNM_000051.3(ATM): c.8851-?_*3591+?dupduplicationLikely pathogenic
134NM_000051.3(ATM): c.8578_8580delTCT (p.Ser2860del)deletionPathogenicrs786203976GRCh38Chr 11, 108345902: 108345904
135NM_000051.3(ATM): c.7638_7646delTAGAATTTC (p.Arg2547_Ser2549del)deletionLikely pathogenic, Pathogenicrs587776547GRCh38Chr 11, 108331887: 108331895
136NM_000051.3(ATM): c.7279_7284delCTTAGG (p.Leu2427_Arg2428del)deletionPathogenicrs796051856GRCh38Chr 11, 108329210: 108329215
137NM_000051.3(ATM): c.5762_5763insNG_009830.1: g.91138_91274single nucleotide variantPathogenicrs774925473GRCh38Chr 11, 108309110: 108309110
138NM_000051.3(ATM): c.7271T> G (p.Val2424Gly)single nucleotide variantPathogenic, risk factorrs28904921GRCh37Chr 11, 108199929: 108199929
139ATMNM_000051.3(ATM): c.103C> T (p.Arg35Ter)single nucleotide variantLikely pathogenic, Pathogenicrs55861249GRCh37Chr 11, 108098533: 108098533
140NM_000051.3(ATM): c.9139C> T (p.Arg3047Ter)single nucleotide variantPathogenicrs121434219GRCh37Chr 11, 108236203: 108236203
141NM_000051.3(ATM): c.7875_7876delTGinsGC (p.Asp2625_Ala2626delinsGluPro)indelLikely pathogenic, Pathogenicrs267606668GRCh37Chr 11, 108203575: 108203576
142ATMNM_000051.3(ATM): c.3245_3247delATCinsTGAT (p.His1082Leufs)indelPathogenicrs587776549GRCh38Chr 11, 108272813: 108272815
143NM_000051.3(ATM): c.7988_7991delTTGT (p.Val2663Alafs)deletionPathogenicrs587776550GRCh38Chr 11, 108333946: 108333949
144ATMNM_000051.3(ATM): c.3576G> A (p.Lys1192=)single nucleotide variantLikely pathogenic, Pathogenicrs587776551GRCh38Chr 11, 108281168: 108281168
145NM_000051.3(ATM): c.7327C> T (p.Arg2443Ter)single nucleotide variantLikely pathogenic, Pathogenicrs121434220GRCh37Chr 11, 108200960: 108200960
146ATMNM_000051.3(ATM): c.2839-581_2839-578delGTAAdeletionPathogenicrs587776552GRCh38Chr 11, 108270483: 108270486
147ATMNM_000051.3(ATM): c.2250G> A (p.Lys750=)single nucleotide variantLikely pathogenic, Pathogenicrs1137887GRCh38Chr 11, 108256340: 108256340

Expression for genes affiliated with Ataxia-Telangiectasia

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Search GEO for disease gene expression data for Ataxia-Telangiectasia.

Pathways for genes affiliated with Ataxia-Telangiectasia

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Pathways related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idSuper pathwaysScoreTop Affiliating Genes
110.2MRE11A, NBN
210.1CHEK2, TP53
310.0ATR, CHEK1
4
Show member pathways
10.0CDKN1A, TP53
5
Show member pathways
10.0ATM, CHEK2, TP53
69.9ATM, CDKN1A, TP53
7
Show member pathways
9.9ATR, BRCA1, RPA2
89.9ATM, BRCA1, CDKN1A
99.8ATM, MRE11A, NBN, RAD50
109.8ATM, ATR, BRCA1, TP53
119.8ATM, ATR, CDKN1A, TP53
12
Show member pathways
9.8ATM, ATR, CDKN1A, TP53
13
Show member pathways
9.7ATR, CHEK1, PCNA, RPA2
149.6ATM, CDKN1A, H2AFX, TP53
159.6ATM, MRE11A, NBN, RAD50, RPA2
16
Show member pathways
9.6ATM, ATR, CHEK1, CHEK2, TP53
17
Show member pathways
9.6ATM, ATR, CHEK1, CHEK2, TP53
18
Show member pathways
9.6ATM, ATR, CHEK1, CHEK2, TP53
19
Show member pathways
9.6ATM, BRCA1, MRE11A, NBN, RAD50
20
Show member pathways
9.5BRCA1, CDKN1A, CHEK1, CHEK2
21
Show member pathways
9.5ATM, CDKN1A, PCNA, RPA2, TP53
229.3ATM, ATR, BRCA1, CDKN1A, PCNA, TP53
239.2ATM, ATR, CHEK1, CHEK2, H2AFX, PRKDC
249.2BRCA1, DCLRE1C, MRE11A, NBN, PRKDC, RAD50
25
Show member pathways
9.1ATM, ATR, CDKN1A, CHEK1, CHEK2, PCNA
269.1ATM, ATR, CDKN1A, CHEK1, CHEK2, PCNA
279.0CDKN1A, CHEK1, NPAT, PCNA, PRKDC, RPA2
288.9ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
298.9ATM, ATR, CDKN1A, CHEK1, CHEK2, PCNA
30
Show member pathways
8.9ATM, ATR, BRCA1, H2AFX, MRE11A, NBN
31
Show member pathways
8.9ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
328.8ATM, ATR, BRCA1, MRE11A, NBN, PCNA
33
Show member pathways
8.8ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
34
Show member pathways
8.7ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
35
Show member pathways
8.7ATM, ATR, BRCA1, CHEK1, MRE11A, NBN
368.7ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
37
Show member pathways
8.7ATM, ATR, CDKN1A, H2AFX, MRE11A, NBN
38
Show member pathways
8.7ATM, ATR, BRCA1, CDKN1A, H2AFX, MRE11A
398.6ATM, BRCA1, CDKN1A, CHEK1, CHEK2, MRE11A
40
Show member pathways
8.3ATM, ATR, BRCA1, CHEK2, H2AFX, MRE11A
41
Show member pathways
8.2ATM, BRCA1, CHEK2, DCLRE1C, H2AFX, MRE11A
42
Show member pathways
8.1ATM, BRCA1, CDKN1A, CHEK1, CHEK2, H2AFX
43
Show member pathways
8.1ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
44
Show member pathways
8.0ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
45
Show member pathways
7.9ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
46
Show member pathways
7.8ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
47
Show member pathways
7.8ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
48
Show member pathways
7.6ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
49
Show member pathways
7.4ATM, ATR, BRCA1, CHEK1, CHEK2, DCLRE1C
507.0ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2

GO Terms for genes affiliated with Ataxia-Telangiectasia

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Cellular components related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1PCNA-p21 complexGO:007055710.7CDKN1A, PCNA
2Mre11 complexGO:003087010.7MRE11A, NBN, RAD50
3nonhomologous end joining complexGO:007041910.6DCLRE1C, PRKDC
4chromosomeGO:000569410.3ATR, BRCA1, H2AFX
5site of double-strand breakGO:003586110.1H2AFX, MRE11A, NBN, RAD50, RPA2
6PML bodyGO:001660510.0ATR, CHEK2, MRE11A, NBN, RPA2, TP53
7replication forkGO:000565710.0CHEK1, H2AFX, NBN, TP53
8nuclear chromatinGO:00007909.9APTX, H2AFX, MRE11A, RAD50, TP53
9condensed nuclear chromosomeGO:00007949.8BRCA1, CHEK1, H2AFX, MRE11A, RAD50
10chromatinGO:00007859.8APTX, CHEK1, H2AFX, RPA2
11chromosome, telomeric regionGO:00007819.5ATM, CHEK1, CHEK2, H2AFX, MRE11A, RPA2
12nuclear chromosome, telomeric regionGO:00007849.3ATM, ATR, DCLRE1C, MRE11A, NBN, PCNA
13nucleusGO:00056347.4APTX, ATM, BRCA1, CDKN1A, CHEK1, CHEK2
14nucleoplasmGO:00056546.3APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1

Biological processes related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idNameGO IDScoreTop Affiliating Genes
1establishment of macromolecular complex localization to telomereGO:009769510.9ATM, ATR
2establishment of RNA localization to telomereGO:009769410.9ATM, ATR
3positive regulation of telomerase catalytic core complex assemblyGO:190488410.9ATM, ATR
4regulation of mitotic recombinationGO:000001910.8MRE11A, RAD50
5mitotic G2 DNA damage checkpointGO:000709510.8MRE11A, NBN
6mitotic G1 DNA damage checkpointGO:003157110.7RPA2, TP53
7positive regulation of DNA damage response, signal transduction by p53 class mediatorGO:004351710.7ATM, ATR
8negative regulation of telomere cappingGO:190435410.6ATM, NBN, RAD50
9positive regulation of protein autophosphorylationGO:003195410.5MRE11A, NBN, RAD50
10cellular response to UVGO:003464410.5ATR, PCNA, TP53
11positive regulation of reactive oxygen species metabolic processGO:200037910.5AGTR1, CDKN1A, TP53
12DNA damage induced protein phosphorylationGO:000697510.4ATM, CHEK1, CHEK2
13cellular response to gamma radiationGO:007148010.4ATM, ATR, H2AFX
14response to gamma radiationGO:001033210.4CHEK2, PRKDC, TP53
15cellular response to X-rayGO:007148110.4ATM, TP53BP1
16telomeric 3 overhang formationGO:003186010.4MRE11A, NBN, RAD50
17telomere maintenance via telomeraseGO:000700410.4ATM, MRE11A, RAD50
18positive regulation of DNA repairGO:004573910.4BRCA1, H2AFX, PCNA
19reciprocal meiotic recombinationGO:000713110.3ATM, MRE11A, RAD50
20V(D)J recombinationGO:003315110.3ATM, DCLRE1C, PRKDC
21interstrand cross-link repairGO:003629710.3ATR, DCLRE1C, RPA2
22intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.3ATM, BRCA1, CHEK2, PRKDC
23intrinsic apoptotic signaling pathwayGO:009719310.3CDKN1A, NBN, TP53
24DNA recombinationGO:000631010.3DCLRE1C, MRE11A, RAD50
25protein sumoylationGO:001692510.3BRCA1, PCNA, TP53, TP53BP1
26DNA duplex unwindingGO:003250810.3MRE11A, NBN, RAD50
27positive regulation of telomere maintenanceGO:003220610.2MRE11A, NBN, RAD50
28telomere maintenance via recombinationGO:000072210.2PCNA, RAD50, RPA2
29regulation of cellular response to heatGO:190003410.2ATM, ATR, RPA2
30cell cycle arrestGO:000705010.2ATM, CDKN1A, NBN, TP53
31DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697710.1ATM, CDKN1A, CHEK2, PCNA, TP53
32peptidyl-serine phosphorylationGO:001810510.1ATM, ATR, CHEK2, PRKDC
33strand displacementGO:00007329.9ATM, BRCA1, MRE11A, NBN, RAD50
34positive regulation of kinase activityGO:00336749.9MRE11A, NBN, RAD50
35DNA synthesis involved in DNA repairGO:00007319.9ATM, BRCA1, MRE11A, NBN, RAD50
36DNA double-strand break processingGO:00007299.9ATM, BRCA1, MRE11A, NBN, RAD50
37replicative senescenceGO:00903999.8ATM, ATR, CDKN1A, CHEK1, CHEK2, TP53
38telomere maintenanceGO:00007239.8DCLRE1C, NBN, PCNA, RAD50, RPA2
39DNA damage checkpointGO:00000779.8ATR, CHEK1, CHEK2, H2AFX, NBN, TP53BP1
40heart developmentGO:00075079.7ATM, MRE11A, PCNA, PRKDC
41nucleic acid phosphodiester bond hydrolysisGO:00903059.7APTX, DCLRE1C, MRE11A, RAD50
42double-strand break repair via homologous recombinationGO:00007249.7ATM, BRCA1, H2AFX, MRE11A, NBN, RAD50
43DNA repairGO:00062819.6ATM, ATR, CHEK1, H2AFX, MRE11A, RAD50
44cell proliferationGO:00082839.6MRE11A, NBN, PCNA, PRKDC, TP53
45response to ionizing radiationGO:00102129.5ATM, BRCA1, DCLRE1C, H2AFX, PRKDC
46double-strand break repairGO:00063029.2BRCA1, CHEK2, DCLRE1C, H2AFX, MRE11A, NBN
47double-strand break repair via nonhomologous end joiningGO:00063039.0ATM, BRCA1, DCLRE1C, H2AFX, MRE11A, NBN
48regulation of signal transduction by p53 class mediatorGO:19017968.9ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
49DNA replicationGO:00062608.6ATM, ATR, BRCA1, CHEK1, MRE11A, NBN
50cellular response to DNA damage stimulusGO:00069748.4APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1

Molecular functions related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1MutLalpha complex bindingGO:003240510.9ATR, PCNA
2DNA-dependent protein kinase activityGO:000467710.9ATM, PRKDC
3p53 bindingGO:000203910.6TP53, TP53BP1, TRIM29
4ATP-dependent DNA helicase activityGO:000400310.5MRE11A, NBN, RAD50
5single-stranded DNA endodeoxyribonuclease activityGO:000001410.4DCLRE1C, MRE11A, RAD50
6double-stranded DNA bindingGO:000369010.3APTX, MRE11A, PRKDC, TP53
7protein kinase activityGO:000467210.2ATM, ATR, CHEK1, CHEK2, PRKDC
8protein serine/threonine kinase activityGO:000467410.0ATM, ATR, CHEK1, CHEK2, PRKDC
9protein N-terminus bindingGO:004748510.0APTX, ATM, NBN, NPAT, RPA2, TP53
10ubiquitin protein ligase bindingGO:00316259.9BRCA1, CDKN1A, CHEK2, RPA2, TP53
11enzyme bindingGO:00198999.6BRCA1, H2AFX, PCNA, PRKDC, RPA2, TP53
12damaged DNA bindingGO:00036849.3APTX, BRCA1, DCLRE1C, H2AFX, NBN, PCNA
13DNA bindingGO:00036778.9ATM, ATR, BRCA1, H2AFX, MRE11A, RAD50
14protein bindingGO:00055156.2AGTR1, APTX, ATM, ATR, BRCA1, CDKN1A

Sources for Ataxia-Telangiectasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet