MCID: ATX030
MIFTS: 76

Ataxia-Telangiectasia malady

Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Reproductive diseases, Skin diseases, Endocrine diseases, Fetal diseases, Blood diseases, Cancer diseases, Immune diseases categories

Aliases & Classifications for Ataxia-Telangiectasia

About this section
Sources:
49OMIM, 11diseasecard, 21GeneReviews, 23Genetics Home Reference, 51Orphanet, 32LifeMap Discovery®, 67UniProtKB/Swiss-Prot, 10Disease Ontology, 68Wikipedia, 45NIH Rare Diseases, 22GeneTests, 46NINDS, 47Novoseek, 12DISEASES, 35MedlinePlus, 65UMLS, 36MeSH, 24GTR, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 34MedGen
See all sources

Aliases & Descriptions for Ataxia-Telangiectasia:

Name: Ataxia-Telangiectasia 49 11 21 23 51 32 67
Ataxia Telangiectasia 32 10 68 45 22 46 47 12 35 65 36 67
Louis-Bar Syndrome 68 21 45 22 23 51 67
at 45 22 67
Telangiectasia, Cerebello-Oculocutaneous 68 23
Ataxia-Telangiectasia Variant 51 24
a-T 68 23
Immunodeficiency with Ataxia Telangiectasia 45
 
Cerebello-Oculocutaneous Telangiectasia 45
Ataxia Telangiectasia Syndrome 23
Boder-Sedgwick Syndrome 10
Louis Bar Syndrome 10
V-at 51
Atm 23
At1 67


Classifications:



Characteristics (Orphanet epidemiological data):

51
ataxia-telangiectasia:
Inheritance: Autosomal recessive; Prevalence: 1-5/10000 (Norway),1-9/1000000 (Norway),1-9/100000 (United States),1-9/1000000 (Europe); Age of onset: Childhood,Infancy; Age of death: adult


External Ids:

OMIM49 208900
Disease Ontology10 DOID:12704
NCIt42 C2887
MeSH36 D001260
Orphanet51 100, 370109
SNOMED-CT59 68504005
ICD10 via Orphanet28 G11.3
MESH via Orphanet37 D001260
UMLS via Orphanet66 C0004135

Summaries for Ataxia-Telangiectasia

About this section
Genetics Home Reference:23 Ataxia-telangiectasia is a rare inherited disorder that affects the nervous system, immune system, and other body systems. This disorder is characterized by progressive difficulty with coordinating movements (ataxia) beginning in early childhood, usually before age 5. Affected children typically develop difficulty walking, problems with balance and hand coordination, involuntary jerking movements (chorea), muscle twitches (myoclonus), and disturbances in nerve function (neuropathy). The movement problems typically cause people to require wheelchair assistance by adolescence. People with this disorder also have slurred speech and trouble moving their eyes to look side-to-side (oculomotor apraxia). Small clusters of enlarged blood vessels called telangiectases, which occur in the eyes and on the surface of the skin, are also characteristic of this condition.

MalaCards based summary: Ataxia-Telangiectasia, also known as ataxia telangiectasia, is related to ataxia-telangiectasia-like disorder and nijmegen breakage syndrome, and has symptoms including polycystic ovaries, strabismus and nystagmus. An important gene associated with Ataxia-Telangiectasia is ATM (ATM Serine/Threonine Kinase), and among its related pathways are miRNA Regulation of DNA Damage Response and PLK3 signaling events. Affiliated tissues include eye, skin and brain, and related mouse phenotypes are adipose tissue and embryogenesis.

NIH Rare Diseases:45 Ataxia telangiectasia (a-t) is an inherited childhood disorder that causes degeneration in the part of the brain that controls motor movements and speech. the condition is characterized by neurological signs, telangiectasias, susceptibility to infections and an increased risk of cancer. mutations in the atm gene cause ataxia-telangiectasia. the condition is inherited in an autosomal recessive pattern. there is no cure for a-t and, currently, no way to slow the progression of the disease. treatment is symptomatic and supportive. last updated: 5/25/2011

OMIM:49 Ataxia-telangiectasia (AT) is an autosomal recessive disorder characterized by cerebellar ataxia, telangiectases,... (208900) more...

MedlinePlus:35 Ataxia-telangiectasia (at) is a rare, inherited disease. it affects the nervous system, immune system, and other body systems. symptoms appear in young children, usually before age 5. they include ataxia - trouble coordinating movements poor balance slurred speech tiny, red spider veins, called telangiectasias, on the skin and eyes lung infections delayed physical and sexual development people with at have an increased risk of developing diabetes and cancers, particularly lymphoma and leukemia. although it affects the brain, people with at usually have normal or above normal intelligence. at has no cure. treatments might improve some symptoms. they include injections to strengthen the immune system, physical and speech therapy, and high-dose vitamin therapy. nih: national institute of neurological disorders and stroke

NINDS:46 Ataxia-telangiectasia is a rare, childhood neurological disorder that causes degeneration in the part of the brain that controls motor movements and speech. The first signs of the disease are unsteady walking and slurred speech, usually occurring during the first five years of life. Telangiectasias (tiny, red "spider" veins), which appear in the corners of the eyes or on the surface of the ears and cheeks, are characteristic of the disease, but are not always present and generally do not appear in the first years of life. About 35 percent of those with A-T develop cancer, most frequently acute lymphocytic leukemia or lymphoma. The most unusual symptom is an acute sensitivity to ionizing radiation, such as X-rays or gamma rays.

UniProtKB/Swiss-Prot:67 Ataxia telangiectasia: A rare recessive disorder characterized by progressive cerebellar ataxia, dilation of the blood vessels in the conjunctiva and eyeballs, immunodeficiency, growth retardation and sexual immaturity. Patients have a strong predisposition to cancer; about 30% of patients develop tumors, particularly lymphomas and leukemias. Cells from affected individuals are highly sensitive to damage by ionizing radiation and resistant to inhibition of DNA synthesis following irradiation.

Wikipedia:68 Ataxia telangiectasia (A-T) (also referred to as Louis–Bar syndrome ) is a rare, neurodegenerative,... more...

GeneReviews summary for ataxia-telangiectas

Related Diseases for Ataxia-Telangiectasia

About this section

Diseases in the Ataxia-Telangiectasia family:

Ataxia-Telangiectasia-Like Disorder

Diseases related to Ataxia-Telangiectasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 4988)
idRelated DiseaseScoreTop Affiliating Genes
1ataxia-telangiectasia-like disorder31.3ATM, CHEK2, MRE11A, NBN, PCNA, RAD50
2nijmegen breakage syndrome30.9ATM, ATR, BRCA1, CHEK2, H2AFX, MRE11A
3cowden disease30.5PCNA, TP53
4breast cancer30.4AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK1
5male reproductive system disease30.4BRCA1, CHEK2, NBN
6pancreatic cancer 430.1BRCA1, NBN
7thrombophilia30.1ATM, BRCA1, CDKN1A, CHEK2, MRE11A, NBN
8brca2 hereditary breast and ovarian cancer syndrome30.1BRCA1, CHEK2, NBN
9riddle syndrome29.7BRCA1, TP53BP1
10breast cancer, childhood29.7BRCA1, CHEK2
11chronic atticoantral disease29.6BRCA1, TP53
12choroid plexus papilloma29.6ATM, BRCA1, CDKN1A, CHEK1, CHEK2, TP53
13bile duct adenocarcinoma29.6ATM, BRCA1, CHEK2
14inverted follicular keratosis29.6CDKN1A, TP53
15ataxia11.5
16neuropathy10.7
17leukemia10.7
18prostate cancer10.7
19schizophrenia10.7
20arthritis10.6
21obesity10.6
22ulnar neuropathy10.6
23congenital heart disease10.6
24cerebellar ataxia10.6
25asthma10.6
26breast disease10.6
27telangiectasis10.6
28pancreatitis10.6
29child syndrome10.5
30cerebellar disease10.5
31nutritional deficiency disease10.5
32spinocerebellar ataxia10.5
33spinocerebellar degeneration10.5
34genetic brain disorders10.5
35neurologic diseases10.5
36ipex syndrome10.5
37kid syndrome10.5
38ataxias and cerebellar or spinocerebellar degeneration10.5
39spinocerebellar atrophy10.5
40tuberculosis10.5
41rheumatoid arthritis10.5
42learning disability10.5
43lung cancer10.5
44female breast carcinoma10.5
45acquired immunodeficiency syndrome10.5
46acute mountain sickness10.5
47sarcoma10.5
48greenberg skeletal dysplasia10.5
49placenta disease10.5
50conduct disorder10.5

Graphical network of the top 20 diseases related to Ataxia-Telangiectasia:



Diseases related to ataxia-telangiectasia

Symptoms for Ataxia-Telangiectasia

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Symptoms by clinical synopsis from OMIM:

208900

Clinical features from OMIM:

208900

Symptoms:

 51 (show all 39)
  • abnormal eye movements/oculomotor disorder
  • strabismus/squint
  • nystagmus
  • anomalies of skin, subcutaneous tissue and mucosae
  • telangiectasiae of the skin
  • telangiectasiae of mucosae
  • premature greying of hair
  • abnormal hepatic enzymes/transaminases
  • repeat respiratory infections
  • thymic aplasia/hypoplasia
  • abnormal/polycystic ovaries
  • late puberty/hypogonadism/hypogenitalism
  • abnormal gait
  • ataxia/incoordination/trouble of the equilibrium
  • movement disorder
  • tremor
  • speech troubles/aphasia/dysphasia/echolalia/mutism/logorrhea/dysprosodia
  • anomalies of the immunitary system
  • immunodeficiency/increased susceptibility to infections/recurrent infections
  • agammaglobulinemia/hypogammaglobulinemia/b-cell deficiency
  • t-cell deficiency/cellular immunity deficiency
  • lymphopenia
  • autosomal recessive inheritance
  • chromosome breakage
  • premature ageing
  • albinism (hair)
  • diabetes mellitus
  • hypertonia/spasticity/rigidity/stiffness
  • seizures/epilepsy/absences/spasms/status epilepticus
  • elocution disorders/dysarthria/dysphonia
  • muscle hypotrophy/atrophy/dystrophy/agenesis/amyotrophy
  • neoplasms/tumors
  • short stature/dwarfism/nanism
  • skin hypoplasia/aplasia/atrophy
  • cafe-au-lait spot
  • small/atrophic/hypoplastic testes/monorchism/microorchidism/anorchia
  • insulin-independent/type 2 diabetes
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • failure to thrive/difficulties for feeding in infancy/growth delay

HPO human phenotypes related to Ataxia-Telangiectasia:

(show all 62)
id Description Frequency HPO Source Accession
1 polycystic ovaries hallmark (90%) HP:0000147
2 strabismus hallmark (90%) HP:0000486
3 nystagmus hallmark (90%) HP:0000639
4 gait disturbance hallmark (90%) HP:0001288
5 tremor hallmark (90%) HP:0001337
6 lymphopenia hallmark (90%) HP:0001888
7 neurological speech impairment hallmark (90%) HP:0002167
8 recurrent respiratory infections hallmark (90%) HP:0002205
9 premature graying of hair hallmark (90%) HP:0002216
10 incoordination hallmark (90%) HP:0002311
11 elevated hepatic transaminases hallmark (90%) HP:0002910
12 abnormality of chromosome stability hallmark (90%) HP:0003220
13 decreased antibody level in blood hallmark (90%) HP:0004313
14 cellular immunodeficiency hallmark (90%) HP:0005374
15 aplasia/hypoplasia of the thymus hallmark (90%) HP:0010515
16 mucosal telangiectasiae hallmark (90%) HP:0100579
17 teleangiectasia of the skin hallmark (90%) HP:0100585
18 seizures typical (50%) HP:0001250
19 hypertonia typical (50%) HP:0001276
20 neurological speech impairment typical (50%) HP:0002167
21 neoplasm typical (50%) HP:0002664
22 skeletal muscle atrophy typical (50%) HP:0003202
23 short stature typical (50%) HP:0004322
24 hypopigmentation of hair typical (50%) HP:0005599
25 abnormality of the testis occasional (7.5%) HP:0000035
26 cafe-au-lait spot occasional (7.5%) HP:0000957
27 type ii diabetes mellitus occasional (7.5%) HP:0005978
28 aplasia/hypoplasia of the skin occasional (7.5%) HP:0008065
29 cognitive impairment occasional (7.5%) HP:0100543
30 autosomal recessive inheritance HP:0000007
31 female hypogonadism HP:0000134
32 sinusitis HP:0000246
33 strabismus HP:0000486
34 conjunctival telangiectasia HP:0000524
35 nystagmus HP:0000639
36 hypoplasia of the thymus HP:0000778
37 diabetes mellitus HP:0000819
38 delayed puberty HP:0000823
39 glucose intolerance HP:0000833
40 cafe-au-lait spot HP:0000957
41 seizures HP:0001250
42 ataxia HP:0001251
43 dysarthria HP:0001260
44 choreoathetosis HP:0001266
45 reduced tendon reflexes HP:0001315
46 dystonia HP:0001332
47 myoclonus HP:0001336
48 tremor HP:0001337
49 abnormality of the hair HP:0001595
50 lymphopenia HP:0001888
51 leukemia HP:0001909
52 bronchiectasis HP:0002110
53 iga deficiency HP:0002720
54 recurrent bronchitis HP:0002837
55 short stature HP:0004322
56 defective b cell differentiation HP:0005357
57 decreased number of cd4+ t cells HP:0005407
58 elevated alpha-fetoprotein HP:0006254
59 immunoglobulin igg2 deficiency HP:0008348
60 abnormal spermatogenesis HP:0008669
61 hodgkin lymphoma HP:0012189
62 non-hodgkin lymphoma HP:0012539

Drugs & Therapeutics for Ataxia-Telangiectasia

About this section

Drugs for Ataxia-Telangiectasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 46)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DopamineapprovedPhase 4281462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
2
AmantadineapprovedPhase 463768-94-52130
Synonyms:
1-Adamantamine
1-Adamantanamine
1-Adamantanamine (8CI)
1-Adamantylamine
1-Aminoadamantane
1-Aminotricyclo(3.3.1.1(sup 3,7))decane
1-adamantanamine
1-adamantylamine
1-aminoadamantane
138576_ALDRICH
665-66-7 (hydrochloride)
768-94-5
AB00514655
AC-11992
AC1L1CZI
AC1Q4UAF
AC1Q5396
ADAMANTANE,1-AMINO
AKOS000113994
AKOS000119324
Adamantamine
Adamantanamine
Adamantylamine
Amant
Amantadina
Amantadina [INN-Spanish]
Amantadine
Amantadine (INN)
Amantadine Base
Amantadine HCL
Amantadine Hydrochloride
Amantadine [INN:BAN]
Amantadine hydrochloride
Amantadine sulfate
Amantadinum
Amantadinum [INN-Latin]
Amantidine
Ambap768-94-5
Aminoadamantane
BIA4304
BIDD:GT0757
BPBio1_000368
BRN 2204333
BSPBio_000334
BSPBio_001570
BSPBio_001822
Bio-0821
C06818
C10H17N
CHEBI:2618
CHEMBL660
CID2130
D07441
DB00915
DivK1c_000815
EINECS 212-201-2
Endantadine
Gen-Amantadine
HMS1791O12
HMS1989O12
HSDB 3202
I14-1101
IDI1_000815
InChI=1/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H
 
KBio1_000815
KBio2_000390
KBio2_002958
KBio2_005526
KBio3_001322
KBioGR_000548
KBioSS_000390
L000868
LS-157049
Lopac-A-1260
Lopac0_000004
Mantadine
MolPort-001-661-700
MolPort-001-760-587
MolPort-001-791-102
NCGC00015036-01
NCGC00015036-07
NCGC00162039-01
NCGC00162039-02
NCGC00162039-03
NCGC00162039-04
NCGC00179597-01
NCIOpen2_001059
NINDS_000815
NSC 341865
NSC341865
NSC83653
OR14310
Oprea1_248648
Pk-merz
Prestwick0_000407
Prestwick1_000407
Prestwick2_000407
Prestwick3_000407
SPBio_000002
SPBio_002273
STK298781
Spectrum2_000081
Spectrum3_000291
Spectrum4_000134
Spectrum5_000772
Spectrum_000030
Symadine
Symmetrel
TCMDC-125869
TL8005280
Tricyclo(3.3.1.1(3,7))-decan-1-amine
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine
Tricyclo(3.3.1.1(sup 3.7))decan-1-amine
Tricyclo(3.3.1.13,7)decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-ylamine
Tricyclo[3.3.1.1(3,7)]decane-1-amine
Tricyclo[3.3.1.1(sup3,7)]decan-1-amine
Tricyclo[3.3.1.1^3,7]decan-1-amine
UNII-BF4C9Z1J53
Viregyt
Virosol
WLN: L66 B6 A B- C 1B ITJ BZ
Wiregyt
adamantan-1-amine
adamantan-1-ylamine
amantadine
tricyclo[3.3.1.1(3,7)]decan-1-ylamine
tricyclo[3.3.1.1(3,7)]decane-1-amine
tricyclo[3.3.1.1~3,7~]decan-1-amine
3
Estradiolapproved, investigationalPhase 4105750-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Depo-estradiol
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol Transdermal System
Estradiol Valerate
Estradiol [USAN:INN]
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol valerate
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
 
Estrofem Forte
Estrogel
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femring
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
Minivelle
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Vivelle Dot
Vivelle-dot
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
4
ClonidineapprovedPhase 41774205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine Hydrochloride
Clonidine Transdermal System
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Kapvay
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Nexiclon
Nexiclon Xr
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
5insulinPhase 44069
6Polyestradiol phosphatePhase 41057
7Estradiol valeratePhase 41057979-32-8
8Insulin, Globin ZincPhase 44069
9Estradiol 3-benzoatePhase 41057
10Adrenergic alpha-2 Receptor AgonistsPhase 4732
11Estradiol 17 beta-cypionatePhase 41083
12arginineNutraceuticalPhase 4346
13
GlycerolexperimentalPhase 317656-81-5753
Synonyms:
1,2,3-Trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerine
Glyceritol
Glycerol
 
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
14UbiquinonePhase 390
15Phase 3
16Complement System ProteinsPhase 3171
17
Coenzyme Q10NutraceuticalPhase 3101303-98-05281915
Synonyms:
(all-E)-2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-2,5-Cyclohexadiene-1,4-dione
(all-E)-2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione
2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-Benzoquinone
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl- 2,5-Cyclohexadiene-1,4-dione
4-Ethyl-5-fluoropyrimidine
Aqua Q 10L10
Aqua Q10
Bio-Quinon
Bio-Quinone Q10
CoQ10
Coenzyme Q10
Ensorb
Kaneka Q10
Kudesan
 
Li-Q-Sorb
Liquid-Q
Neuquinon
Neuquinone
PureSorb Q 40
Q 10AA
Q-Gel
Q-Gel 100
Ubidecarenone
Ubiquinone 10
Ubiquinone 50
Ubiquinone Q10
Ubiquinone-10
Unbiquinone
Unispheres Q 10
18LecithinNutraceuticalPhase 357
19
Miconazoleapproved, investigationalPhase 2291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
20
CaspofunginapprovedPhase 260179463-17-3, 162808-62-0468682, 2826718
Synonyms:
(4R,5S)-5-((2-Aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(P-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
(4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
(4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin b0
1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0
162808-62-0
AC1L45LR
AC1LAHR5
AC1MCVUN
AR-1K4318
CASPO
CHEBI:474180
CHEMBL374999
CHEMBL499808
CID151068
CID2826718
CID468682
Cancidas
Cancidas (TM)
 
Cancidas (TN)
Capsofungin
Caspofungin
Caspofungin (INN)
Caspofungin [INN]
Caspofungin acetate
D07626
DB00520
HSDB 7476
L-743,872
LS-186994
LS-187303
LS-187635
M991
MK-0991
N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide
Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]- (9CI)
UNII-F0XDI6ZL63
[1(R)-hydroxyethyl]-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0(9,13)]heptacosane-2,5,8,14,17,23-hexaone diacetate
n-{(2r,6s,9s,11r,12s,14as,15s,20s,23s,25as)-12-[(2-aminoethyl)amino]-20-[(1r)-3-amino-1-hydroxypropyl]-23-[(1s,2s)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1r)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1h-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide
nchembio.184-comp7
21
PaclitaxelapprovedPhase 2250533069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
22
GemcitabineapprovedPhase 2180095058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine Hydrochloride
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
23EchinocandinsPhase 266
24
Irinotecanapproved, investigationalPhase 1101397682-44-5, 100286-90-660838
Synonyms:
(+)-Irinotecan
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
1u65
97682-44-5
AC-7469
AC1L1U0Z
AC1Q6PGI
BRD-K08547377-003-02-4
BSPBio_002346
Bio-0054
Biotecan
Biotecan (TN)
C16641
C33H38N4O6
CHEBI:105985
CHEMBL481
CID60838
CP0
Campothecin-11
Campto
Camptosar
 
Camptosar, Campto, CPT-11, Irinotecan
Camptothecin-11
D08086
DB00762
FT-0083650
HSDB 7607
IRINOTECAN HYDROCHLORIDE Trihydrate
IRINOTECAN, CPT-11
Irinotecan
Irinotecan (INN)
Irinotecan Hcl
Irinotecan Hydrochloride
Irinotecan Hydrochloride Trihydrate
Irinotecan [INN:BAN]
Irinotecan hydrochloride
Irinotecanum
Irinotecanum [INN-Latin]
LS-44589
NCI60_005051
NSC728073
S1198_Selleck
TL8006026
UNII-7673326042
irinotecan
25
CamptothecinexperimentalPhase 11967689-03-424360
Synonyms:
(+)-camptothecin
(+)-camptothecine
(s)-(+)-camptothecin
 
(s)-camptothecin
20(S)-Camptothecin
21,22-Secocamptothecin-21-oic acid lactone
Camptothecine
D-camptothecin
26
Doxorubicinapproved, investigational152523214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
27
Etoposideapproved112733419-42-036462
Synonyms:
(-)-Etoposide
121471-01-0
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
51854-34-3
76576-58-4
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one
AB00438905
AC1L1FN8
AC1L1VT3
AC1L6246
AC1NR4OG
AC1O4WGG
AC1O7M1N
AC1Q47JJ
Ambap33419-42-0
BPBio1_000673
BRD-K37798499-001-02-5
BSPBio_000611
Bio1_000489
Bio1_000978
Bio1_001467
C01576
CCRIS 2392
CHEBI:4911
CHEBI:588795
CHEMBL44657
CID11758093
CID284997
CID3310
CID36462
CID5284558
CID6419930
CID6610299
CPD000112002
D00125
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
E0675
E1383_SIGMA
EINECS 251-509-1
EPE
EPEG
ETOP
Epipodophyllotoxin
Epipodophyllotoxin VP-16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
Eposin, Vepesid, VP-16, Toposar, Etoposide
 
Etopol
Etopophos
Etopophos (phosphate salt)
Etoposid
Etoposide
Etoposide (JP15/USP/INN)
Etoposide (VP16)
Etoposide Phosphate
Etoposide [USAN:INN:BAN:JAN]
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
HMS1569O13
HMS2052N05
HMS2089F14
HSDB 6517
I06-0248
KBioSS_002410
LS-1214
Lastet
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-003-983-431
MolPort-004-905-001
MolPort-004-955-161
NCGC00025056-02
NChemBio.2007.10-comp19
NK 171
NSC 141540
NSC-141540
NSC141540
Prestwick0_000396
Prestwick1_000396
Prestwick2_000396
Prestwick3_000396
Prestwick_211
S1225_Selleck
SAM001246880
SMR000112002
SPBio_002532
ST056353
Toposar
UNII-6PLQ3CP4P3
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16-213
VePESID (TN)
VePesid
Vepesid
Vepesid J
Vepeside
ZINC03830818
ZINC03938684
Zuyeyidal
etoposide
nchembio.573-comp8
nchembio873-comp2
trans-Etoposide
28
Methotrexateapproved13871959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
Methopterin
Methotextrate
 
Methotrate
Methotrexat
Methotrexate
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metoject
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Otrexup
Rasuvo
Rheumatrex
Rheumatrex Dose Pack
Trexall
29
Prednisoneapproved120853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
30
Vincristineapproved, investigational8362068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
31
Vinblastineapproved218865-21-413342, 241903, 13342, 241903
Synonyms:
(2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine
(2xi,3beta,4'beta,19xi)-vincaleukoblastine
(3aR-(3aalpha,4beta,5beta,5abeta,9(3R*,5S*,7R*,9S*),10bR*,13aalpha))-methyl 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino(8,1-cd)carbazole-5-carboxylate
143-67-9
1z2b
29060-LE
865-21-4
AC-20335
AC1L21JC
AC1L68D2
AC1MXZJ2
BIDD:PXR0201
BRD-K01188359-065-02-5
BSPBio_001228
BSPBio_003594
Bio-0111
C07201
C46H58N4O9
CCRIS 9002
CHEBI:171516
CHEBI:27375
CHEMBL159
CHEMBL607706
CID13342
CID241903
CID3823887
CID6710780
D08675
DB00570
EINECS 212-734-0
HMS2090K05
HSDB 3263
KBio3_003033
LS-1859
LS-187263
 
MolPort-002-518-262
MolPort-005-910-359
NCGC00022585-04
NCGC00181127-01
NCI-C04842
NCI60_004200
NChemBio.2007.10-comp22
NDC 0002-1452-01
NSC 47842
Neuro_000020
Nincaluicolflastine
Rozevin
SPBio_000680
STOCK1N-38480
Spectrum2_000890
Spectrum3_001994
UNII-5V9KLZ54CY
VLB
VR-8
Velban
Velbe
Vinblastin
Vinblastina
Vinblastina (TN)
Vinblastina [DCIT]
Vinblastina [Dcit]
Vinblastine
Vinblastine (INN)
Vinblastine Sulfate
Vinblastine [INN:BAN]
Vinblastinum
Vinblastinum [INN-Latin]
Vincaleucoblastin
Vincaleucoblastine
Vincaleukoblastine
Vincoblastine
nchembio873-comp22
vinblastine
32
Daunorubicinapproved24420830-81-330323
Synonyms:
(+)-Daunomycin
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside
(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
11006-54-5
11048-29-6
1407-15-4
149541-57-1
20830-81-3
23942-76-9
27576-81-4
28020-80-6
AB00514669
AC1L1JCP
AC1Q29OI
AI3-52942
Acetyladriamycin
Anthracyline
Antibiotics From Streptomyces Coeruleorubidus
Antibiotics from Streptomyces coeruleorubidus
BPBio1_000389
BRD-K43389675-003-02-7
BRN 1445583
BSPBio_000353
C01907
CCRIS 914
CHEBI:41977
CHEMBL178
CID30323
Cerubidin
Cerubidine
D07776
DAUNORUBICIN HCL
DB00694
DM1
Daunamycin
Daunarubicinum
Dauno-Rubidomycine
DaunoXome
DaunoXome (TN)
Daunoblastin
Daunoblastine
Daunomycin
 
Daunomycin Hydrochloride
Daunomycin, Hydrochloride
Daunorrubicina
Daunorubicin
Daunorubicin (INN)
Daunorubicin (liposomal)
Daunorubicin Hcl
Daunorubicin Hydrochloride
Daunorubicin [INN:BAN]
Daunorubicin, Hydrochloride
Daunorubicina
Daunorubicine
Daunorubicinum
Daunorubicinum [INN-Latin]
Daunoxome
EINECS 244-069-7
FI 6339
FI6339
HMS2089H04
HMS2091K06
HSDB 5095
LMPK13050002
LS-187381
LS-997
Leukaemomycin C
MolPort-002-533-961
NCGC00024246-05
NCGC00024246-06
NCGC00025173-01
NCI-C04693
NChemBio.2007.10-comp14
NSC 83142
NSC-82151
Ondena
Prestwick3_000487
RCRA waste no. U059
RP 13057
Rcra Waste No. U059
Rp 13057 Hydrochloride
Rubidomycin
Rubidomycin Hydrochloride
Rubomycin
Rubomycin C
Tocris-1467
UNII-ZS7284E0ZP
VS-103
daunorubicin
nchembio723-comp2
33
Cyclophosphamideapproved, investigational252550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
34
Asparaginaseapproved1969015-68-3
Synonyms:
Elspar
Erwinase
 
Kidrolase
L-asparagine amidohydrolase
Putative L-asparaginase precursor
35
Dexamethasoneapproved, investigational180650-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
36
Cytarabineapproved, investigational995147-94-46253
Synonyms:
(beta-D-Arabinofuranosyl)cytosine
(beta-D-arabinofuranosyl)cytosine
1-.beta.-D-arabinofuranosyl-cytosine
1-Arabinofuranosylcytosine
1-beta -D-Arabinofaranosylcytosine
1-beta -D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta -D-Arabinofuranosylcytosine
1-beta-D-Arabinofaranosylcytosine
1-beta-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta-D-Arabinofuranosyl-Cytosine
1-beta-D-Arabinofuranosylcytosine
1-beta-D-Arabinofuranosylcytosine, Cytosine Arabinoside
1-beta-D-Arabinosyl-Cytosine
1-beta-D-Arabinosylcytosine
147-94-4
1beta -Arabinofuranasylcytosine
1beta -D-Arabinofuranosylcytosine
1beta -D-Arabinosylcytosine
1beta-Arabinofuranasylcytosine
1beta-D-Arabinofuranosylcytosine
1beta-D-Arabinosylcytosine
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl- [CAS]
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl
30399_FLUKA
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin [Czech]
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
4-Amino-1-b-D-arabinofuranosyl-2-(1H)-pyrimidinone
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon [Czech]
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
69-74-9 (hydrochloride)
AC-1075
AC1L1M4F
AC1Q52OJ
AI3-52329
AR3
Alexan
Ara-C
Ara-C, Cytosine Arabinoside, Cytosar-U, Cytarabine
Ara-Cytidine
AraC
Arabinocytidine
Arabinofuranosyl Cytidine
Arabinofuranosylcytosine
Arabinosyl Cytosine
Arabinosylcytosine
Arabitin
Aracytidine
Aracytin
Aracytine
Arafcyt
BIDD:GT0371
BIDD:PXR0139
BTB15125
Beta-cytosine arabinoside
C02961
C1768_SIGMA
C2035
C9H13N3O5
CCRIS 913
CHEBI:28680
CHEMBL803
CHX 3311
CID6253
CPD000449317
CYTARABINE (SEE ALSO CYTARABINE HYDROCHLORIDE 69-74-9)
Citarabina
Citarabina [INN-Spanish]
Cytarabin
Cytarabina
Cytarabine
Cytarabine (JP15/USP/INN)
 
Cytarabine [USAN:INN:BAN:JAN]
Cytarabine liposome injection
Cytarabinoside
Cytarabinum
Cytarabinum [INN-Latin]
Cytarbel
Cytonal
Cytosar
Cytosar-U
Cytosine 1-beta-D-arabinofuranoside
Cytosine arabinofuranoside
Cytosine arabinose
Cytosine arabinoside
Cytosine arabinoside (VAN)
Cytosine beta-D-arabinofuranoside
Cytosine beta-D-arabinofuranoside hydrochloride
Cytosine beta-D-arabinoside
Cytosine, beta -D-arabinoside
Cytosine, beta-D-arabinoside
Cytosine-1-beta-D-arabinofuranoside
Cytosine-1-beta-D-arabinofuranoside hydrochloride
Cytosine-beta -D-arabinofuranoside
Cytosine-beta -arabinoside
Cytosine-beta-D-arabinofuranoside
Cytosine-beta-arabinoside
Cytosinearabinoside
D00168
DB00987
DepoCyte
Depocyt
Depocyt (TN)
Depocyt (liposomal)
Depocyte
EINECS 205-705-9
Erpalfa
FT-0082880
HMS2051K19
HMS2090A18
HSDB 3049
Intrathecal (injected into the spinal fluid) DepoCyt
Intrathecal cytarabine (also known as ara-C)
Iretin
LS-860
Lopac0_000316
MLS000758310
MLS001066340
MolPort-001-792-509
NCGC00093356-03
NCGC00093356-04
NCGC00093356-05
NCI-C04728
NSC 287459
NSC287459
S1648_Selleck
SAM001247012
SMR000449317
SR-01000075773-3
Spongocytidine
TL8001048
Tarabine
U 19920A
U-19,920
U-19920
UNII-04079A1RDZ
Udicil
ZINC03795098
beta -D-arabinosylcytosine
beta -arabinosylcytosine
beta -cytosine arabinoside
beta-Ara C
beta-Ara c
beta-Arabinosylcytosine
beta-Cytosine arabinoside
beta-D-Arabinosylcytosine
cytarabine
cytarabine liposome injection
cytosine-β-D-arabinofuranoside
37
Procarbazineapproved67671-16-94915
Synonyms:
1-Methyl-2-(P-(isopropylcarbamoyl)benzyl)hydrazine
1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine
2-(P-Isopropylcarbamoylbenzyl)-1-methylhydrazine
2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine
366-70-1 (mono-hydrochloride)
4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide
671-16-9
AC-4547
AC1L1J8E
Ambap671-16-9
BIDD:GT0183
BPBio1_001369
BRN 0958270
BSPBio_001244
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)- (9CI)
C07402
C12H19N3O
CAS-366-70-1
CB 400-497
CCRIS 2389
CHEMBL1321
CID4915
D08423
DB01168
EINECS 211-582-2
HMS2090J09
HSDB 3250
I01-8931
IBZ
Ibenzmethyzin
Ibenzmethyzine
LS-7671
MBH
MIH
Matulane
MolPort-005-940-370
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
 
N-(1-Methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
N-4-Isopropylcarbamoylbenzyl-n'-methylhydrazine
N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide
N-Isopropyl-P-(2-methylhydrazinomethyl)-benzamide
N-Isopropyl-alpha-(2-methylhydrazino)-P-toluamide
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
NCGC00016438-01
NCGC00016438-02
NCI60_041703
NCIOpen2_004074
NSC-77213
Natulan
Natulanar
P-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
PCX
Prestwick0_001112
Prestwick1_001112
Prestwick2_001112
Prestwick3_001112
Procarbazin
Procarbazin [German]
Procarbazina
Procarbazina [INN-Spanish]
Procarbazine (INN)
Procarbazine Monohydrochloride
Procarbazine [INN:BAN]
Procarbazine hydrochloride
Procarbazinum
Procarbazinum [INN-Latin]
Ro 4-6467
Ro 4-6467/1
SPBio_003112
SRI-10847
UNII-35S93Y190K
p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide
procarbazine
38
BaclofenapprovedPhase 0901134-47-02284
Synonyms:
( inverted question mark)-Baclofen
(+-)-Baclofen
(+/-)- beta-(Aminoethyl)-4- chlorobenzenepropanoic acid
(+/-)-BACLOFEN
(+/-)-beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
(?)-Baclofen
1134-47-0
4-Amino-3-(4-chlorophenyl)butanoic acid
4-Amino-3-(4-chlorophenyl)butyric acid
62594-36-9
AB00051921
AC-4530
AC1L1DC6
ASTA Medica Brand of Baclofen
AWD, Baclofen
Alphapharm Brand of Baclofen
Apo Baclofen
Apo-Baclofen
ApoBaclofen
Apotex Brand of Baclofen
Ashbourne Brand of Baclofen
Athena Brand of Baclofen
Atrofen
B 5399
B3343
B5399_SIGMA
BPBio1_000012
BPBio1_000750
BRD-A84174873-001-05-2
BRN 2104494
BSPBio_000010
BSPBio_001880
Ba 34647
Ba-34,647
Ba-34647
Ba34,647
Ba34647
Baclofen
Baclofen (JP15/USP/INN)
Baclofen (R,S)
Baclofen AWD
Baclofen Alphapharm Brand
Baclofen Apotex Brand
Baclofen Ashbourne Brand
Baclofen Athena Brand
Baclofen Ciba-Geigy Brand
Baclofen Irex Brand
Baclofen Isis Brand
Baclofen Medtronic Brand
Baclofen Novartis Brand
Baclofen Nu-Pharm Brand
Baclofen Pharmascience Brand
Baclofen [USAN:INN:BAN:JAN]
Baclofene
Baclofene Irex
Baclofene [INN-French]
Baclofene-Irex
BaclofeneIrex
Baclofeno
Baclofeno [INN-Spanish]
Baclofenum
Baclofenum [INN-Latin]
Baclon
Baclophen
Baclospas
Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-(9CI)
Biomol-NT_000251
C 34647Ba
C10H12ClNO2
CCRIS 3722
CHEBI:2972
CHEMBL701
CIBA-34,647-BA
CIBA34,647BA
CID2284
Chlorophenyl GABA
Ciba 34,647-Ba
Ciba Geigy Brand of Baclofen
Ciba-Geigy Brand of Baclofen
Clofen
D001418
D00241
DB00181
DL-4-Amino-3-P-chlorophenylbutanoic acid
DL-4-Amino-3-p-chlorophenylbutanoic acid
DL-Baclofen
 
DivK1c_000001
EINECS 214-486-9
EU-0100163
GABA, Chlorophenyl
Gabalon
Gablofen
Gen Baclofen
Gen-Baclofen
GenBaclofen
Genpharm
HMS1568A12
HMS1920E21
HMS2091M03
HMS500A03
I01-1934
IDI1_000001
Irex Brand of Baclofen
Isis Brand of Baclofen
KBio1_000001
KBio2_000466
KBio2_003034
KBio2_005602
KBio3_001380
KBioGR_000650
KBioSS_000466
Kemstro
Kemstro (TN)
L000002
LS-77134
Lebic
Lioresal
Lioresal (TN)
Lioresal Intrathecal
Lopac0_000163
MLS000028480
Medtronic Brand of Baclofen
MolPort-002-051-370
NCGC00015156-05
NCGC00015156-12
NCGC00023843-03
NCGC00024579-03
NCGC00024579-04
NCGC00024579-05
NCGC00024579-06
NINDS_000001
NSC329137
Novartis Brand of Baclofen
Nu Baclo
Nu Pharm Brand of Baclofen
Nu-Baclo
Nu-Baclofen
Nu-Pharm Brand of Baclofen
NuBaclo
Oprea1_440627
PCP-GABA
PMS Baclofen
PMSBaclofen
Pharmascience Brand of Baclofen
Pms-Baclofen
Prestwick0_000085
Prestwick1_000085
Prestwick2_000085
Prestwick3_000085
Prestwick_85
SMP1_000036
SMR000058294
SPBio_000044
SPBio_001949
SPECTRUM1500135
STK535284
STOCK2S-30552
Spectrum2_000092
Spectrum3_000310
Spectrum4_000245
Spectrum5_000852
Spectrum_000066
UNII-H789N3FKE8
UPCMLD-DP142
UPCMLD-DP142:001
baclofen
beta-(4-Chlorophenyl)gaba
beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
beta-(Aminomethyl)-P-chlorohydrocinnamic acid
beta-(Aminomethyl)-p-chlorohydrocinnamic acid
beta-(P-Chlorophenyl)-gamma-aminobutyric acid
beta-(p-Chlorophenyl)-gamma-aminobutyric acid
gamma-Amino-beta-(P-chlorophenyl)butyric acid
gamma-Amino-beta-(p-chlorophenyl)butyric acid
39
DoxilApproved June 1999152531703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
40
butyric acidexperimentalPhase 010107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
41Dexamethasone acetate18061177-87-3
426-Mercaptopurine181
43Etoposide phosphate1127
44BB 11011848
45Dexamethasone 21-phosphate1806
46Immunoglobulin A102

Interventional clinical trials:

(show all 22)
idNameStatusNCT IDPhase
1Amantadine for Improving Neurologic Symptoms in Ataxia-TelangiectasiaCompletedNCT00950196Phase 4
2Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)RecruitingNCT01052623Phase 4
3Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)CompletedNCT00656409Phase 3
4Evolution of Albumin on AOA1 Patients Supplemented With Coenzyme Q10Active, not recruitingNCT02333305Phase 3
5Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell TransplantCompletedNCT00110045Phase 2
6Efficacy Study of Olaparib With Paclitaxel Versus Paclitaxel in Gastric Cancer PatientsActive, not recruitingNCT01063517Phase 2
7Gemcitabine Hydrochloride Alone or With VX-970 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerNot yet recruitingNCT02595892Phase 2
8A Study of MK-4827 for the Treatment of Mantle Cell Lymphoma (MK-4827-002)WithdrawnNCT01244009Phase 2
9Study of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory CancerRecruitingNCT02630199Phase 1
10VX-970 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryNot yet recruitingNCT02595931Phase 1
11Body Composition and Hormonal Status in Ataxia TelangiectasiaCompletedNCT02345200
12Study for Treatment of Cancer in Children With Ataxia-telangiectasiaCompletedNCT00187057
13International Ataxia Rating Scale in Younger PatientsCompletedNCT01942850
14Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-TRecruitingNCT02285348
15Pancreatic Cancer Screening of High-Risk Individuals in ArkansasRecruitingNCT02309632
16Rare Disease Patient Registry: Coordination of Rare Diseases at SanfordRecruitingNCT01793168
17Baclofen Treatment of Ataxia TelangiectasiaActive, not recruitingNCT00640003Phase 0
18The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied LongitudinallyActive, not recruitingNCT00951886
19Development of iPS From Donated Somatic Cells of Patients With Neurological DiseasesActive, not recruitingNCT00874783
20Susceptibility to Infections in Ataxia TelangiectasiaEnrolling by invitationNCT02345135
21Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia PatientsNot yet recruitingNCT01075438
22Cell-Based Approaches For Modeling and Treating Ataxia-TelangiectasiaNot yet recruitingNCT02246491

Search NIH Clinical Center for Ataxia-Telangiectasia

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Ataxia-Telangiectasia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Ataxia-Telangiectasia:
Renexus
Embryonic/Adult Cultured Cells Related to Ataxia-Telangiectasia:
Human retinal stem cells secreting CNTF, PMIDs: 16805711, 17508034, 16505355, 23049090, 15684670, 12581701, 15223826, 18830926


Cochrane evidence based reviews: Ataxia Telangiectasia

Genetic Tests for Ataxia-Telangiectasia

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Genetic tests related to Ataxia-Telangiectasia:

id Genetic test Affiliating Genes
1 Ataxia-Telangiectasia22 ATM
2 Ataxia-Telangiectasia Syndrome24

Anatomical Context for Ataxia-Telangiectasia

About this section

MalaCards organs/tissues related to Ataxia-Telangiectasia:

33
Eye, Skin, Brain, Lung, Breast, T cells, B cells

Animal Models for Ataxia-Telangiectasia or affiliated genes

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MGI Mouse Phenotypes related to Ataxia-Telangiectasia:

38 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.7ATR, BRCA1, CDKN1A, PCNA, PRKDC, TP53
2MP:00053809.1ATM, ATR, BRCA1, CDKN1A, CHEK1, MRE11A
3MP:00053788.4AGTR1, ATM, ATR, BRCA1, CDKN1A, H2AFX
4MP:00020068.1ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
5MP:00107687.8AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK1
6MP:00053977.8ATM, ATR, BRCA1, CDKN1A, CHEK2, DCLRE1C
7MP:00053797.8ATM, ATR, BRCA1, CDKN1A, CHEK1, H2AFX
8MP:00053847.6APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1
9MP:00053877.6AGTR1, ATM, ATR, BRCA1, CDKN1A, CHEK2
10MP:00053897.6ATM, ATR, BRCA1, CDKN1A, CHEK1, H2AFX

Publications for Ataxia-Telangiectasia

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Articles related to Ataxia-Telangiectasia:

(show top 50)    (show all 788)
idTitleAuthorsYear
1
Caffeine Suppresses Apoptosis of Bladder Cancer RT4 Cells in Response to Ionizing Radiation by Inhibiting Ataxia Telangiectasia Mutated-Chk2-p53 Axis. (26521794)
2015
2
Primary Diffuse Large B-cell Lymphoma Arising in the Tongue Accompanied by Ataxia-telangiectasia: A Case Report. (26266230)
2015
3
Multi-drugs resistant acne rosacea in a child affected by Ataxia-Telangiectasia: successful treatment with Isotretinoin. (25881033)
2015
4
Altered corticomotor-cerebellar integrity in young ataxia telangiectasia patients. (25042086)
2014
5
Inhibition of Ataxia Telangiectasia Mutated (ATM) Kinase Suppresses Herpes Simplex Virus Type 1 (HSV-1) Keratitis. (24370835)
2013
6
Infections of the respiratory system in patients with ataxia-telangiectasia. (23761391)
2013
7
Twelve novel Atm mutations identified in Chinese ataxia telangiectasia patients. (23807571)
2013
8
Ataxia telangiectasia: learning from previous mistakes. (23242084)
2012
9
Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia. (22006793)
2012
10
Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study. (22213089)
2012
11
Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. (21321203)
2011
12
Ataxia telangiectasia: A report of two cousins and review of literature. (22563157)
2011
13
Ataxia telangiectasia and Rad3-related overexpressing cancer cells induce prolonged Ga88 arrest and develop resistance to ionizing radiation. (21294646)
2011
14
Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. (21245316)
2011
15
Ataxia telangiectasia: Family management. (20838492)
2010
16
Update on the management of the immunodeficiency in ataxia-telangiectasia. (20477642)
2009
17
Clinical spectrum of ataxia-telangiectasia in adulthood. (19535770)
2009
18
Ataxia-telangiectasia: atypical presentation and toxicity of cancer treatment. (19650357)
2009
19
Ataxia-Telangiectasia and mechanical ventilation: a word of caution. (19085928)
2009
20
Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes. (18381427)
2008
21
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. (18424439)
2008
22
Ataxia-telangiectasia mutated expression is associated with tobacco smoke exposure in esophageal cancer tissues and benzo[a]pyrene diol epoxide in cell lines. (17019709)
2007
23
Comparison of ataxia-telangiectasia mutated protein expression in diffuse large B-cell lymphomas of primary central nervous system and non-central nervous system origin. (17516749)
2007
24
Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma. (16461462)
2006
25
Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection. (16952553)
2006
26
Modifications of nuclear architecture and chromatin organization in ataxia telangiectasia cells are coupled to changes of gene transcription. (16795050)
2006
27
Exclusion/confirmation of ataxia-telangiectasia via cell-cycle testing. (16411093)
2006
28
Mutation analysis of the ATM gene in two Chinese patients with ataxia telangiectasia. (16380133)
2006
29
Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation. (17178844)
2006
30
Molecular basis of ataxia telangiectasia and related diseases. (16038621)
2005
31
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. (15510216)
2004
32
ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation. (12645530)
2003
33
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. (14695167)
2003
34
Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia. (12393664)
2002
35
A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells. (11744712)
2002
36
Immunoblot analysis for laboratory diagnosis of ataxia-telangiectasia: use of Epstein-Barr virus-transformed or phytohemagglutinin-stimulated lymphoblasts for detection of ATM protein. (10780798)
2000
37
Spontaneous and oxidative stress-induced programmed cell death in lymphocytes from patients with ataxia telangiectasia (AT). (10606975)
2000
38
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. (10500142)
1999
39
Ataxia-telangiectasia in the Japanese population: identification of R1917X, W2491R, R2909G, IVS33+2T-->A, and 7883del5, the latter two being relatively common mutations. (9792410)
1998
40
ATM mutations in patients with ataxia telangiectasia screened by a hierarchical strategy. (9711876)
1998
41
G2 chromosomal radiosensitivity in fibroblasts of ataxia-telangiectasia heterozygotes and a Li-Fraumeni syndrome patient with radioresistant cells. (9343108)
1997
42
Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster. (8786135)
1996
43
The ataxia-telangiectasia-variant genes 1 and 2 are distinct from the ataxia-telangiectasia gene on chromosome 11q23.1. (7573059)
1995
44
An early-onset recessive cerebellar disorder with distal amyotrophy and, in two patients, gross myoclonia: a probable ataxia telangiectasia variant. (7788963)
1995
45
Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene. (7923077)
1994
46
Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. (8247533)
1993
47
Heterozygous manifestations in four autosomal recessive human cancer-prone syndromes: ataxia telangiectasia, xeroderma pigmentosum, Fanconi anemia, and Bloom syndrome. (1279391)
1992
48
Ataxia-telangiectasia in a child with vaccine-associated paralytic poliomyelitis. (1517916)
1992
49
Physical mapping of the human chromosome 11q23 region containing the ataxia-telangiectasia locus. (2331673)
1990
50
Gonadoblastoma and dysgerminoma with ataxia-telangiectasia. (990441)
1976

Variations for Ataxia-Telangiectasia

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UniProtKB/Swiss-Prot genetic disease variations for Ataxia-Telangiectasia:

67 (show all 39)
id Symbol AA change Variation ID SNP ID
1ATMp.Lys224GluVAR_010801
2ATMp.Pro292LeuVAR_010802
3ATMp.Ile323ValVAR_010803
4ATMp.Phe570SerVAR_010808
5ATMp.Asn768AspVAR_010812
6ATMp.Arg785CysVAR_010813
7ATMp.Leu950ArgVAR_010815
8ATMp.Leu1001GlnVAR_010816
9ATMp.His1082LeuVAR_010819
10ATMp.Glu1091AspVAR_010820
11ATMp.Leu1420ProVAR_010823
12ATMp.Leu1465ProVAR_010826
13ATMp.Pro1566ArgVAR_010827
14ATMp.Thr1743IleVAR_010831
15ATMp.Val1913GlyVAR_010836
16ATMp.Asp2016GlyVAR_010838
17ATMp.Gly2063GluVAR_010839
18ATMp.Ala2067AspVAR_010840
19ATMp.Ser2218CysVAR_010844
20ATMp.Arg2227CysVAR_010846
21ATMp.Val2424GlyVAR_010854
22ATMp.Tyr2470AspVAR_010858
23ATMp.Trp2491ArgVAR_010860
24ATMp.His2554AspVAR_010862
25ATMp.Asp2625GlnVAR_010863
26ATMp.Leu2656ProVAR_010865
27ATMp.Glu2668GlyVAR_010868
28ATMp.Ile2702ArgVAR_010870
29ATMp.Ala2726ValVAR_010874
30ATMp.Cys2824TyrVAR_010878
31ATMp.Phe2827CysVAR_010879
32ATMp.Pro2829LeuVAR_010880
33ATMp.Arg2832CysVAR_010881
34ATMp.Arg2849ProVAR_010882
35ATMp.Ser2855ArgVAR_010883
36ATMp.Gly2867ArgVAR_010886
37ATMp.Glu2904GlyVAR_010889
38ATMp.Arg2909GlyVAR_010890
39ATMp.Arg3008CysVAR_010893

Clinvar genetic disease variations for Ataxia-Telangiectasia:

5 (show all 79)
id Gene Variation Type Significance SNP ID Assembly Location
1ATMNM_000051.3(ATM): c.1339C> T (p.Arg447Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587779815GRCh38Chr 11, 108250804: 108250804
2ATMNM_000051.3(ATM): c.1564_1565delGA (p.Glu522Ilefs)deletionPathogenicrs587779817GRCh38Chr 11, 108251029: 108251030
3ATMNM_000051.3(ATM): c.170G> A (p.Trp57Ter)single nucleotide variantPathogenicrs587779818GRCh38Chr 11, 108227873: 108227873
4ATMNM_000051.3(ATM): c.3372C> G (p.Tyr1124Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587779833GRCh38Chr 11, 108279578: 108279578
5ATMNM_000051.3(ATM): c.3802delG (p.Val1268Terfs)deletionPathogenicrs587779834GRCh38Chr 11, 108284282: 108284282
6ATMNM_000051.3(ATM): c.5228C> T (p.Thr1743Ile)single nucleotide variantLikely pathogenicrs587779844GRCh38Chr 11, 108301698: 108301698
7ATMNM_000051.3(ATM): c.5290delC (p.Leu1764Tyrfs)deletionLikely pathogenic, Pathogenicrs587779846GRCh38Chr 11, 108301760: 108301760
8ATMNM_000051.3(ATM): c.6100C> T (p.Arg2034Ter)single nucleotide variantPathogenicrs532480170GRCh38Chr 11, 108316015: 108316015
9NM_000051.3(ATM): c.8494C> T (p.Arg2832Cys)single nucleotide variantLikely pathogenic, Pathogenicrs587779872GRCh38Chr 11, 108345818: 108345818
10NM_000051.3(ATM): c.8786+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs17174393GRCh38Chr 11, 108353881: 108353881
11ATMNM_000051.3(ATM): c.5652dupA (p.Thr1885Asnfs)duplicationPathogenicrs587778077GRCh37Chr 11, 108175557: 108175557
12ATMNM_000051.3(ATM): c.1024_1027delAAAG (p.Glu343Ilefs)deletionLikely pathogenic, Pathogenicrs587780612GRCh38Chr 11, 108247086: 108247089
13ATMNM_000051.3(ATM): c.477_481delATCTC (p.Ser160Alafs)deletionPathogenicrs587780624GRCh38Chr 11, 108235815: 108235819
14NM_000051.3(ATM): c.7788G> A (p.Glu2596=)single nucleotide variantPathogenicrs587780639GRCh38Chr 11, 108332037: 108332037
15NM_000051.3(ATM): c.8035_8050del16 (p.Asn2679Serfs)deletionPathogenicrs587780640GRCh38Chr 11, 108334993: 108335008
16NM_000051.3(ATM): c.8266A> T (p.Lys2756Ter)single nucleotide variantLikely pathogenic, Pathogenicrs371638537GRCh38Chr 11, 108335959: 108335959
17NM_000051.3(ATM): c.9079dupA (p.Ser3027Lysfs)duplicationLikely pathogenicrs587780645GRCh38Chr 11, 108365416: 108365416
18ATMNM_000051.3(ATM): c.1402_1403delAA (p.Lys468Glufs)deletionLikely pathogenic, Pathogenicrs587781347GRCh37Chr 11, 108121594: 108121595
19ATMNM_000051.3(ATM): c.2921+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs587781558GRCh37Chr 11, 108141874: 108141874
20NM_000051.3(ATM): c.7913G> A (p.Trp2638Ter)single nucleotide variantLikely pathogenic, Pathogenicrs377349459GRCh37Chr 11, 108203613: 108203613
21ATMNM_000051.3(ATM): c.7096G> T (p.Glu2366Ter)single nucleotide variantLikely pathogenic, Pathogenicrs587781672GRCh37Chr 11, 108199754: 108199754
22ATMNM_000051.3(ATM): c.5908C> T (p.Gln1970Ter)single nucleotide variantPathogenicrs587781722GRCh37Chr 11, 108181032: 108181032
23ATMNM_000051.3(ATM): c.5712dupA (p.Ser1905Ilefs)duplicationLikely pathogenic, Pathogenicrs587781730GRCh37Chr 11, 108178661: 108178661
24NM_000051.3(ATM): c.9023G> A (p.Arg3008His)single nucleotide variantLikely pathogenicrs587781894GRCh37Chr 11, 108236087: 108236087
25ATMNM_000051.3(ATM): c.4776+2T> Csingle nucleotide variantPathogenicrs587781927GRCh38Chr 11, 108293479: 108293479
26ATMNM_000051.3(ATM): c.3994-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs587782276GRCh38Chr 11, 108287598: 108287598
27NM_000051.3(ATM): c.9022C> T (p.Arg3008Cys)single nucleotide variantLikely pathogenic, Pathogenicrs587782292GRCh37Chr 11, 108236086: 108236086
28NM_000051.3(ATM): c.8147T> C (p.Val2716Ala)single nucleotide variantLikely pathogenicrs587782652GRCh37Chr 11, 108205832: 108205832
29NM_000051.3(ATM): c.7876G> C (p.Ala2626Pro)single nucleotide variantPathogenicrs267606669GRCh37Chr 11, 108203576: 108203576
30NM_000051.3(ATM): c.8264_8268delATAAG (p.Tyr2755Cysfs)deletionPathogenicrs730881294GRCh38Chr 11, 108335957: 108335961
31ATMNM_000051.3(ATM): c.2251-10T> Gsingle nucleotide variantPathogenicrs730881346GRCh38Chr 11, 108257471: 108257471
32ATMNM_000051.3(ATM): c.6095G> A (p.Arg2032Lys)single nucleotide variantLikely pathogenic, Pathogenicrs139770721GRCh38Chr 11, 108315911: 108315911
33ATMNM_000051.3(ATM): c.6154G> A (p.Glu2052Lys)single nucleotide variantLikely pathogenic, Pathogenicrs202206540GRCh38Chr 11, 108316069: 108316069
34ATMNM_000051.3(ATM): c.6679C> T (p.Arg2227Cys)single nucleotide variantLikely pathogenic, Pathogenicrs564652222GRCh38Chr 11, 108325416: 108325416
35ATMNM_000051.3(ATM): c.2720_2723delGTGT (p.Cys907Terfs)deletionPathogenicrs786202695GRCh37Chr 11, 108139218: 108139221
36NM_000051.3(ATM): c.8977C> T (p.Arg2993Ter)single nucleotide variantLikely pathogenic, Pathogenicrs770641163GRCh37Chr 11, 108235935: 108235935
37NM_000051.3(ATM): c.8293G> A (p.Gly2765Ser)single nucleotide variantLikely pathogenicrs748634900GRCh37Chr 11, 108213973: 108213973
38NM_000051.3(ATM): c.8786+1G> Csingle nucleotide variantPathogenicrs17174393GRCh37Chr 11, 108224608: 108224608
39ATMNM_000051.3(ATM): c.2T> C (p.Met1Thr)single nucleotide variantLikely pathogenic, Pathogenicrs786203606GRCh37Chr 11, 108098353: 108098353
40ATMNM_000051.3(ATM): c.2921+1G> Csingle nucleotide variantLikely pathogenicrs587781558GRCh38Chr 11, 108271147: 108271147
41NM_000051.3(ATM): c.8851-?_*(1_?)deldeletionPathogenicGRCh37Chr 11, 108235809: 108236236
42ATMNM_000051.3(ATM): c.72+1G> Asingle nucleotide variantLikely pathogenicrs786204088GRCh38Chr 11, 108227697: 108227697
43NM_000051.3(ATM): c.7702_7703delAG (p.Asp2569Terfs)deletionPathogenicrs759965045GRCh38Chr 11, 108331951: 108331952
44ATMNM_000051.3(ATM): c.1561_1562delAG (p.Glu522Ilefs)deletionPathogenicrs751357509GRCh38Chr 11, 108251026: 108251027
45ATMNM_000051.3(ATM): c.5644C> T (p.Arg1882Ter)single nucleotide variantLikely pathogenicrs786204433GRCh38Chr 11, 108304822: 108304822
46NM_000051.3(ATM): c.7927+5delGdeletionLikely pathogenicrs786204437GRCh38Chr 11, 108332905: 108332905
47ATMNM_000051.3(ATM): c.640delT (p.Ser214Profs)deletionLikely pathogenicrs786204543GRCh38Chr 11, 108244096: 108244096
48ATMNM_000051.3(ATM): c.3G> A (p.Met1Ile)single nucleotide variantLikely pathogenicrs781404312GRCh38Chr 11, 108227627: 108227627
49ATMNM_000051.3(ATM): c.802C> T (p.Gln268Ter)single nucleotide variantLikely pathogenicrs557012154GRCh37Chr 11, 108115654: 108115654
50ATMNM_000051.3(ATM): c.5188C> T (p.Arg1730Ter)single nucleotide variantLikely pathogenicrs764389018GRCh38Chr 11, 108301658: 108301658
51NM_000051.3(ATM): c.8307G> A (p.Trp2769Ter)single nucleotide variantLikely pathogenicrs778269655GRCh38Chr 11, 108343260: 108343260
52NM_000051.3(ATM): c.8876_8879delACTG (p.Asp2959Glyfs)deletionLikely pathogenicrs786204726GRCh37Chr 11, 108235834: 108235837
53ATMNM_000051.3(ATM): c.1524delT (p.Gly509Glufs)deletionLikely pathogenicrs786204737GRCh38Chr 11, 108250989: 108250989
54ATMNM_000051.3(ATM): c.5515C> T (p.Gln1839Ter)single nucleotide variantLikely pathogenicrs786204751GRCh38Chr 11, 108304693: 108304693
55NM_000051.3(ATM): c.7876G> C (p.Ala2626Pro)single nucleotide variantPathogenicrs267606669GRCh37Chr 11, 108203576: 108203576
56ATMNM_000051.3(ATM): c.6049dupA (p.Ser2017Lysfs)duplicationPathogenicrs797045030GRCh38Chr 11, 108315865: 108315865
57NM_000051.3(ATM): c.7926A> C (p.Arg2642Ser)single nucleotide variantLikely pathogenicGRCh38Chr 11, 108332899: 108332899
58ATMNM_000051.3(ATM): c.1284_1291delTAACTGTG (p.Asn429Alafs)deletionPathogenicGRCh37Chr 11, 108121476: 108121483
59ATMNM_000051.3(ATM): c.140C> G (p.Ser47Ter)single nucleotide variantPathogenicrs774185390GRCh38Chr 11, 108227843: 108227843
60ATMNM_000051.3(ATM): c.2413C> T (p.Arg805Ter)single nucleotide variantPathogenicrs780619951GRCh38Chr 11, 108259022: 108259022
61ATMNM_000051.3(ATM): c.6750_6751insCTCA (p.Lys2253Hisfs)insertionPathogenicGRCh38Chr 11, 108325487: 108325488
62ATMNM_000051.3(ATM): c.7240C> T (p.Gln2414Ter)single nucleotide variantPathogenicGRCh37Chr 11, 108199898: 108199898
63ATMNM_000051.3(ATM): c.748C> T (p.Arg250Ter)single nucleotide variantPathogenicrs772821016GRCh38Chr 11, 108244873: 108244873
64NM_000051.3(ATM): c.7985T> A (p.Val2662Asp)single nucleotide variantPathogenicGRCh37Chr 11, 108204670: 108204670
65ATMNM_000051.3(ATM): c.2113delT (p.Tyr705Thrfs)deletionPathogenicGRCh37Chr 11, 108124755: 108124755
66NM_000051.3(ATM): c.8578_8580delTCT (p.Ser2860del)deletionPathogenicrs786203976GRCh38Chr 11, 108345902: 108345904
67ATMNM_000051.3(ATM): c.7279_7284delCTTAGG (p.Leu2427_Arg2428del)deletionPathogenicrs796051856GRCh38Chr 11, 108329210: 108329215
68ATMNM_000051.3(ATM): c.7271T> G (p.Val2424Gly)single nucleotide variantPathogenic, risk factorrs28904921GRCh37Chr 11, 108199929: 108199929
69NM_000051.3(ATM): c.7636_7644delTCTAGAATT (p.Arg2547_Ser2549del)deletionPathogenicrs587776547GRCh38Chr 11, 108331885: 108331893
70ATMNM_000051.3(ATM): c.103C> T (p.Arg35Ter)single nucleotide variantPathogenicrs55861249GRCh37Chr 11, 108098533: 108098533
71NM_000051.3(ATM): c.9139C> T (p.Arg3047Ter)single nucleotide variantPathogenicrs121434219GRCh37Chr 11, 108236203: 108236203
72NM_000051.3(ATM): c.7883_7887delTTATA (p.Ile2629Serfs)deletionPathogenicrs587776548GRCh38Chr 11, 108332856: 108332860
73ATMNM_000051.3(ATM): c.3245_3247delATCinsTGAT (p.His1082Leufs)indelPathogenicrs587776549GRCh38Chr 11, 108272813: 108272815
74NM_000051.3(ATM): c.7988_7991delTTGT (p.Val2663Alafs)deletionPathogenicrs587776550GRCh38Chr 11, 108333946: 108333949
75ATMNM_000051.3(ATM): c.3576G> A (p.Lys1192=)single nucleotide variantPathogenicrs587776551GRCh38Chr 11, 108281168: 108281168
76ATMNM_000051.3(ATM): c.7327C> T (p.Arg2443Ter)single nucleotide variantLikely pathogenic, Pathogenicrs121434220GRCh37Chr 11, 108200960: 108200960
77ATMNM_000051.3(ATM): c.2839-581_2839-578deldeletionPathogenicrs587776552GRCh38Chr 11, 108270483: 108270486
78ATMNM_000051.3(ATM): c.2250G> A (p.Lys750=)single nucleotide variantLikely pathogenic, Pathogenicrs1137887GRCh38Chr 11, 108256340: 108256340
79ATMNM_000051.3(ATM): c.146C> G (p.Ser49Cys)single nucleotide variantrisk factorrs1800054GRCh37Chr 11, 108098576: 108098576

Expression for genes affiliated with Ataxia-Telangiectasia

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Search GEO for disease gene expression data for Ataxia-Telangiectasia.

Pathways for genes affiliated with Ataxia-Telangiectasia

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Pathways related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show all 45)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1MRE11A, NBN
210.1CHEK2, TP53
310.0ATR, CHEK1
4
Show member pathways
10.0CDKN1A, TP53
5
Show member pathways
9.9MRE11A, NBN, RAD50
6
Show member pathways
9.9ATM, CDKN1A, TP53
79.8ATM, BRCA1, CDKN1A
89.8ATM, MRE11A, NBN, RAD50
99.8ATM, ATR, BRCA1, TP53
109.7ATM, ATR, CDKN1A, TP53
11
Show member pathways
9.7ATM, ATR, CDKN1A, TP53
12
Show member pathways
9.6ATR, CHEK1, PCNA, RPA2
139.6ATM, CDKN1A, H2AFX, TP53
14
Show member pathways
9.5ATM, BRCA1, MRE11A, NBN, RAD50
159.5ATM, MRE11A, NBN, RAD50, RPA2
16
Show member pathways
9.5ATM, ATR, CHEK1, CHEK2, TP53
17
Show member pathways
9.5ATM, ATR, CHEK1, CHEK2, TP53
189.5ATM, ATR, CHEK1, CHEK2, TP53
19
Show member pathways
9.5BRCA1, CDKN1A, CHEK1, CHEK2
20
Show member pathways
9.4ATM, CDKN1A, PCNA, RPA2, TP53
219.3ATM, ATR, BRCA1, CDKN1A, PCNA, TP53
229.2BRCA1, DCLRE1C, MRE11A, NBN, PRKDC, RAD50
239.2ATM, ATR, CHEK1, CHEK2, H2AFX, PRKDC
249.1ATM, ATR, CDKN1A, CHEK1, CHEK2, PCNA
258.9CDKN1A, CHEK1, NPAT, PCNA, PRKDC, RPA2
268.9ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
278.9ATM, ATR, CDKN1A, CHEK1, CHEK2, PCNA
28
Show member pathways
8.8ATM, ATR, BRCA1, H2AFX, MRE11A, NBN
298.8ATM, ATR, BRCA1, MRE11A, NBN, PCNA
30
Show member pathways
8.8ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
31
Show member pathways
8.7ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
32
Show member pathways
8.7ATM, ATR, BRCA1, CHEK1, CHEK2, MRE11A
338.7ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
34
Show member pathways
8.7ATM, ATR, BRCA1, CHEK1, MRE11A, NBN
35
Show member pathways
8.6ATM, ATR, BRCA1, CDKN1A, H2AFX, MRE11A
368.6ATM, BRCA1, CDKN1A, CHEK1, CHEK2, MRE11A
37
Show member pathways
8.6ATM, ATR, CDKN1A, H2AFX, MRE11A, NBN
388.3ATM, ATR, BRCA1, CHEK2, H2AFX, MRE11A
39
Show member pathways
8.1ATM, BRCA1, CDKN1A, CHEK1, CHEK2, H2AFX
40
Show member pathways
7.9ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
41
Show member pathways
7.8ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
42
Show member pathways
7.5ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
43
Show member pathways
7.3ATM, ATR, BRCA1, CHEK1, CHEK2, DCLRE1C
44
Show member pathways
7.2ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2
456.8ATM, ATR, BRCA1, CDKN1A, CHEK1, CHEK2

GO Terms for genes affiliated with Ataxia-Telangiectasia

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Cellular components related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1PCNA-p21 complexGO:007055710.6CDKN1A, PCNA
2Mre11 complexGO:003087010.6MRE11A, NBN, RAD50
3XY bodyGO:000174110.4ATR, H2AFX
4chromosomeGO:000569410.1ATR, BRCA1, H2AFX
5PML bodyGO:001660510.0ATR, CHEK2, NBN, RPA2, TP53
6nuclear chromatinGO:000079010.0APTX, H2AFX, MRE11A, TP53
7site of double-strand breakGO:003586110.0H2AFX, MRE11A, NBN, RAD50, RPA2
8condensed nuclear chromosomeGO:00007949.9BRCA1, CHEK1, H2AFX, MRE11A
9chromatinGO:00007859.8APTX, CHEK1, H2AFX, MRE11A, RPA2
10replication forkGO:00056579.7CHEK1, H2AFX, NBN, TP53, TP53BP1
11nuclear chromosome, telomeric regionGO:00007849.3DCLRE1C, MRE11A, NBN, PCNA, PRKDC, RAD50
12chromosome, telomeric regionGO:00007819.2ATM, CHEK1, CHEK2, H2AFX, MRE11A, NBN
13nucleusGO:00056346.9APTX, ATM, BRCA1, CDKN1A, CHEK1, DCLRE1C
14nucleoplasmGO:00056546.3APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1

Biological processes related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of DNA damage response, signal transduction by p53 class mediatorGO:004351710.8ATM, ATR
2regulation of mitotic recombinationGO:000001910.8MRE11A, RAD50
3B cell lineage commitmentGO:000232610.7PRKDC, TP53
4T cell lineage commitmentGO:000236010.7PRKDC, TP53
5determination of adult lifespanGO:000834010.7ATM, TP53
6DNA damage response, signal transduction by p53 class mediatorGO:003033010.7NBN, TP53
7mitotic G2 DNA damage checkpointGO:000709510.6MRE11A, NBN
8DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697810.6BRCA1, TP53
9chromosome breakageGO:003105210.6BRCA1, TP53
10somitogenesisGO:000175610.6ATM, PRKDC, TP53
11regulation of double-strand break repair via homologous recombinationGO:001056910.6CHEK1, RPA2
12telomere maintenance via telomeraseGO:000700410.5MRE11A, RAD50
13V(D)J recombinationGO:003315110.5ATM, DCLRE1C, PRKDC
14response to gamma radiationGO:001033210.4CHEK2, PRKDC, TP53
15positive regulation of protein autophosphorylationGO:003195410.4MRE11A, NBN, RAD50
16mitotic cell cycle arrestGO:007185010.4CDKN1A, TP53
17meiotic cell cycleGO:005132110.4H2AFX, MRE11A, NBN
18DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697710.4ATM, CDKN1A, TP53
19cellular response to UVGO:003464410.4ATR, PCNA, TP53
20DNA damage induced protein phosphorylationGO:000697510.3ATM, CHEK1, CHEK2
21reciprocal meiotic recombinationGO:000713110.3ATM, MRE11A, RAD50
22intrinsic apoptotic signaling pathwayGO:009719310.3CDKN1A, NBN, TP53
23cellular response to gamma radiationGO:007148010.3ATM, ATR, H2AFX
24regulation of cellular response to heatGO:190003410.3ATM, ATR, RPA2
25positive regulation of DNA repairGO:004573910.3BRCA1, H2AFX, PCNA
26interstrand cross-link repairGO:003629710.2ATR, DCLRE1C, RPA2
27DNA duplex unwindingGO:003250810.2MRE11A, NBN, RAD50
28intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.2ATM, BRCA1, CHEK2, PRKDC
29chromosome organizationGO:005127610.1DCLRE1C, MRE11A, RAD50, TP53
30positive regulation of kinase activityGO:003367410.1MRE11A, NBN, RAD50
31cell cycle arrestGO:000705010.1ATM, CDKN1A, NBN, TP53
32replicative senescenceGO:009039910.1ATM, ATR, CHEK1, CHEK2, TP53
33mitotic G1 DNA damage checkpointGO:003157110.0RPA2, TP53
34cellular response to heatGO:003460510.0ATM, ATR, CDKN1A, RPA2
35base-excision repairGO:000628410.0MRE11A, PCNA, RPA2, TP53
36positive regulation of reactive oxygen species metabolic processGO:20003799.9AGTR1, CDKN1A, TP53
37DNA recombinationGO:00063109.9BRCA1, DCLRE1C, MRE11A, RAD50, RPA2
38nucleic acid phosphodiester bond hydrolysisGO:00903059.8APTX, DCLRE1C, MRE11A, RAD50
39regulation of cell proliferationGO:00421279.8AGTR1, BRCA1, CHEK1, TP53
40double-strand break repair via synthesis-dependent strand annealingGO:00450039.8ATM, BRCA1, MRE11A, NBN, RAD50
41DNA replicationGO:00062609.7ATR, BRCA1, CHEK1, RPA2
42heart developmentGO:00075079.5ATM, MRE11A, PCNA, PRKDC
43DNA damage checkpointGO:00000779.5ATM, ATR, CHEK1, CHEK2, H2AFX, NBN
44telomere maintenanceGO:00007239.3ATM, DCLRE1C, NBN, PCNA, PRKDC, RAD50
45response to ionizing radiationGO:00102129.2ATM, BRCA1, DCLRE1C, H2AFX, PRKDC
46double-strand break repair via nonhomologous end joiningGO:00063038.9ATM, BRCA1, DCLRE1C, H2AFX, MRE11A, NBN
47double-strand break repair via homologous recombinationGO:00007248.4ATM, ATR, BRCA1, CHEK1, H2AFX, MRE11A
48cellular response to DNA damage stimulusGO:00069747.7APTX, ATM, ATR, BRCA1, CDKN1A, CHEK1
49double-strand break repairGO:00063027.5APTX, ATM, ATR, BRCA1, CHEK1, CHEK2
50DNA repairGO:00062817.1APTX, ATM, ATR, BRCA1, CHEK1, CHEK2

Molecular functions related to Ataxia-Telangiectasia according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1MutLalpha complex bindingGO:003240510.9ATR, PCNA
2DNA-dependent protein kinase activityGO:000467710.8ATM, PRKDC
3phosphotransferase activity, alcohol group as acceptorGO:001677310.7ATM, ATR, PRKDC
4p53 bindingGO:000203910.6TP53, TP53BP1, TRIM29
5single-stranded DNA endodeoxyribonuclease activityGO:000001410.5DCLRE1C, MRE11A, RAD50
6ATP-dependent DNA helicase activityGO:000400310.5MRE11A, NBN, RAD50
7double-stranded DNA bindingGO:000369010.2APTX, MRE11A, PRKDC, TP53
8protein N-terminus bindingGO:004748510.0APTX, ATM, NBN, NPAT, RPA2, TP53
9protein kinase activityGO:00046729.9ATM, ATR, CHEK1, CHEK2, PRKDC
10protein serine/threonine kinase activityGO:00046749.9ATM, ATR, CHEK1, CHEK2, PRKDC
11ubiquitin protein ligase bindingGO:00316259.9BRCA1, CDKN1A, CHEK2, RPA2, TP53
12enzyme bindingGO:00198999.6BRCA1, H2AFX, PRKDC, RPA2, TP53
13damaged DNA bindingGO:00036848.9APTX, BRCA1, DCLRE1C, H2AFX, NBN, PCNA
14DNA bindingGO:00036778.5APTX, ATM, ATR, BRCA1, H2AFX, MRE11A
15protein bindingGO:00055156.6AGTR1, APTX, ATM, ATR, BRCA1, CDKN1A

Sources for Ataxia-Telangiectasia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet