MCID: ATH003
MIFTS: 71

Atherosclerosis malady

Cardiovascular diseases category

Summaries for Atherosclerosis

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33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Atherosclerosis is a disease in which plaque builds up inside your arteries. plaque is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. over time, plaque hardens and narrows your arteries. that limits the flow of oxygen-rich blood to your body. atherosclerosis can lead to serious problems, including coronary artery disease. these arteries supply blood to your heart. when they are blocked, you can suffer angina or a heart attack. carotid artery disease. these arteries supply blood to your brain. when they are blocked you can suffer a stroke. peripheral arterial disease. these arteries are in your arms, legs and pelvis. when they are blocked, you can suffer from numbness, pain and sometimes infections. atherosclerosis usually doesn't cause symptoms until it severely narrows or totally blocks an artery. many people don't know they have it until they have a medical emergency. a physical exam, imaging, and other diagnostic tests can tell if you have it. medicines can slow the progress of plaque buildup. your doctor may also recommend procedures such as angioplasty to open the arteries, or surgery on the coronary or carotid arteries. lifestyle changes can also help. these include following a healthy diet, getting regular exercise, maintaining a healthy weight, quitting smoking, and managing stress. nih: national heart, lung, and blood institute

MalaCards: Atherosclerosis, also known as atherosclerosis, susceptibility to, is related to hypertension and coronary artery disease. An important gene associated with Atherosclerosis is ALOX5 (arachidonate 5-lipoxygenase), and among its related pathways are Metabolism and Lipoprotein metabolism. The compounds lipid and cholesterol have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and monocytes, and related mouse phenotypes are homeostasis/metabolism and immune system.

Wikipedia:63 Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of... more...

Aliases & Classifications for Atherosclerosis

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Sources:
8Disease Ontology, 9diseasecard, 46OMIM, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 27ICD9CM, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

atherosclerosis 8 46 10 44 33 60
atherosclerosis, susceptibility to 9


External Ids:

Disease Ontology8 DOID:1936
ICD9CM27 440
NCIt39 C35768
MeSH34 D050197
ICD1025 I70

Related Diseases for Atherosclerosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Atherosclerosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 341)
idRelated DiseaseScoreTop Affiliating Genes
1hypertension31.1SELE, OLR1, LPA, PPARG, CCL2
2coronary artery disease31.1PPARG, LPA, ATHS, MMP3, GJA4, OLR1
3diabetes mellitus31.0CETP, SELE, PPARG, CCL2, HMGCR, OLR1
4obesity31.0ALOX5, CETP, SELE, MMP3, LPA, PPARG
5familial hypercholesterolemia30.9HMGCR, CETP
6myocardial infarction30.9CETP, ALOX5AP, HMGCR, OLR1, SAA1, LPA
7arthritis30.8SELE, SAA1, CCL2, MMP3, HMGCR, ALOX5
8systemic lupus erythematosus30.8SELE, CCL2, ALOX5, MMP3
9rheumatoid arthritis30.8ALOX5AP, ALOX5, ALOX15, HMGCR, LPA, CCL2
10vascular disease30.8OLR1, HMGCR, SELE, APOC2, LPA, PPARG
11stroke, ischemic30.7LPA, ALOX5AP, SELE, HMGCR
12type 2 diabetes mellitus30.7SELE, CETP, CCL2, APOC2, PPARG, LPA
13hyperhomocysteinemia30.6LPA, SELE, CCL2
14ischemic heart disease30.6OLR1, LPA, HMGCR, CETP
15arteriosclerosis30.6CCL2, HMGCR, PPARG
16coronary stenosis30.5LPA, CETP, OLR1
17fatty liver disease30.5HMGCR, PPARG, CETP
18essential hypertension30.5LPA, CETP
19pneumonia30.5ALOX5AP, CCL2
20alzheimer's disease30.4LPA, APOC2, PPARG, HMGCR, MSR1, OLR1
21peripheral vascular disease30.4SELE, CCL2
22ischemia30.4OLR1, ALOX5, SELE, MMP3, HMGCR
23hyperglycemia30.4HMGCR, LPA, PPARG, CETP, SELE
24peritonitis30.4CCL2, ALOX5
25acute myocardial infarction30.3HMGCR, SELE, SAA1, LPA, OLR1
26xanthomatosis30.3MSR1
27familial hyperlipidemia30.2APOC2, CETP, LPA, HMGCR
28dementia30.2LPA, CETP, MMP3
29lipodystrophy30.2HMGCR, PPARG
30diabetic nephropathy30.1LPA, PPARG, HMGCR, CCL2
31hyperlipidemia type 330.1HMGCR, CETP, LPA
32polycystic ovary syndrome30.1PPARG
33osteoporosis30.1MMP3, ESR1, ALOX5, ALOX15, HMGCR
34tangier disease30.1PPARG, LPA, CETP
35glucose intolerance30.1APOC2, CETP, PPARG
36vasculitis30.1SELE, CCL2
37hepatitis b30.1MMP3
38asthma30.0ALOX5, SELE, ALOX15, CCL2, CETP, ALOX5AP
39psoriasis30.0ALOX5, SELE, CCL2
40nephrotic syndrome30.0CETP, HMGCR, LPA
41sitosterolemia30.0HMGCR, ABCG8
42hepatitis c30.0HMGCR
43proteinuria29.9ALOX5, HMGCR, OLR1, LPA, CETP, APOC2
44colon cancer29.8PPARG, MMP3, SELE, HMGCR, ALOX5
45prostate cancer29.8ESR1, PPARG, MSR1, ALOX15, ALOX5
46endometriosis29.8CCL2, HMGCR, ESR1, MMP3
47abdominal aortic aneurysm29.8CCL2, MMP3, CETP
48cerebrovascular disease29.8HMGCR, CETP
49angioedema29.8ALOX5
50hypothyroidism29.8CETP, LPA

Graphical network of the top 20 diseases related to Atherosclerosis:



Diseases related to atherosclerosis

Clinical Features for Atherosclerosis

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Drugs & Therapeutics for Atherosclerosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Atherosclerosis

Drug clinical trials:

Search ClinicalTrials for Atherosclerosis

Search NIH Clinical Center for Atherosclerosis

Search CenterWatch for Atherosclerosis

Genetic Tests for Atherosclerosis

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Anatomical Context for Atherosclerosis

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Sources:
30LifeMap Discovery™, 32MalaCards
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MalaCards organs/tissues related to Atherosclerosis:

32
Heart, Endothelial, Monocytes, Smooth muscle, Kidney, Testes, Brain, Liver, Lung, T cells, Bone, Myeloid, Ovary, Adipocyte, B cells, Thyroid, Skin, Colon, Prostate, Pancreas, Spinal cord, Globus pallidus, Placenta, Bone marrow, Skeletal muscle, Retina, Lymph node, Eye, Pituitary

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Atherosclerosis:
id TissueAnatomical CompartmentCell Relevance
1 EndotheliumArteriesArterial Endothelial Cells Potential therapeutic candidate, affected by disease
2 HeartCoronary Capillary Plexus  Affected by disease
3 HeartCoronary Vessels  Affected by disease

Animal Models for Atherosclerosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Atherosclerosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537612.9MMP3, SELE, CCL2, SAA1, ALOX5, ALOX5AP
2MP:000538712.5CCL2, PPARG, MMP3, OLR1, MSR1, ALOX15
3MP:000538512.2ALOX5, ESR1, SELE, MSR1, OLR1, GJA4
4MP:000539711.7ALOX15, ALOX5, PPARG, ESR1, SELE, MSR1
5MP:000537011.5CEL, ESR1, SELE, ABCG8, CCL2, PPARG
6MP:000537511.4ALOX5, CEL, ESR1, PPARG, CCL2

Publications for Atherosclerosis

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Sources:
50PubMed
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Articles related to Atherosclerosis:

(show top 50)    (show all 4340)
idTitleAuthorsYear
1
Coronary atherosclerosis burden, but not transient troponin elevation, predicts long-term outcome in recreational marathon runners. (24253174)
2014
2
Chemokines in Atherosclerosis: Proceedings Resumed. (24436368)
2014
3
Molecular imaging of inflammation in atherosclerosis. (24312156)
2013
4
Macrophages in atherosclerosis: a dynamic balance. (23995626)
2013
5
Is the lumen diameter of peripheral arteries a good marker of the extent of coronary atherosclerosis? (24049020)
2013
6
Partial ligation-induced carotid artery occlusion induces leukocyte recruitment and lipid accumulation--a shear stress model of atherosclerosis. (23054191)
2013
7
Using advanced noninvasive imaging techniques to probe the links between regional coronary artery endothelial dysfunction and atherosclerosis. (24296299)
2013
8
Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies. (23149595)
2013
9
Renin-sensitive microRNAs correlate with atherosclerosis plaque progression. (24152824)
2013
10
Long-term complications of diabetes and co-morbidities contributing to atherosclerosis in diabetic population of Mirpur, Azad Kashmir. (24392524)
2013
11
Fetuin-A does not explain ethnic disparity in cardiometabolic risk factors and subclinical atherosclerosis between Hispanics and non-Hispanic whites. (20946008)
2011
12
Thickened carotid intima media thickness and carotid atherosclerosis among lupus nephritis patients: the role of traditional and lupus-specific factors. (21816023)
2011
13
Adiponectin levels, cardiometabolic risk factors and markers of subclinical atherosclerosis in children. (18774612)
2010
14
MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study. (20064641)
2010
15
Relationship between CX3CR1 genetic polymorphism and carotid atherosclerosis. (20047517)
2010
16
Visfatin (nampt) and ghrelin as novel markers of carotid atherosclerosis in patients with type 2 diabetes. (19834878)
2010
17
Increased atherogenic lipoproteins are associated with cognitive impairment: effects of statins and subclinical atherosclerosis. (19266697)
2009
18
C-reactive protein and homocysteine as risk factors of atherosclerosis]. (18853656)
2008
19
Association of human carboxypeptidase E exon5 gene polymorphisms with angiographical characteristics of coronary atherosclerosis in a Chinese population. (18501121)
2008
20
Differential impact of age, sex, and hypertension on aortic atherosclerosis: the Framingham Heart Study. (17991874)
2008
21
TLRs are important inflammatory factors in atherosclerosis and may be a therapeutic target. (17689203)
2008
22
Assessment and reproducibility of aortic atherosclerosis magnetic resonance imaging: impact of 3-Tesla field strength and parallel imaging. (18708860)
2008
23
Insulin resistance as a risk factor for carotid atherosclerosis: a comparison of the Homeostasis Model Assessment and the short insulin tolerance test. (18309150)
2008
24
Monounsaturated fatty acyl-coenzyme A is predictive of atherosclerosis in human apoB-100 transgenic, LDLr-/- mice. (17277381)
2007
25
Niacin plus Simvastatin Reduces Coronary Stenosis Progression Among Patients with Metabolic Syndrome Despite a Modest Increase in Insulin Resistance: A Subgroup Analysis of the HDL-Atherosclerosis Treatment Study (HATS). (18591993)
2007
26
Apolipoprotein AI mimetic peptides: possible new agents for the treatment of atherosclerosis. (17408115)
2007
27
Relationship between aortic valve calcification and aortic atherosclerosis: a transoesophageal echocardiography study. (16886126)
2006
28
DRB1-TNF-alpha-TNF-beta haplotype is strongly associated with severe aortoiliac occlusive disease, a clinical form of atherosclerosis. (16386648)
2005
29
Effects of ethanol on lipids and atherosclerosis. (15006415)
2004
30
Role of mechanical stress in monocytes/macrophages: implications for atherosclerosis. (15320477)
2003
31
Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis. (12588754)
2003
32
Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis. (14582455)
2003
33
Lipid metabolism: peroxisome proliferator-activated receptor-alpha and atherosclerosis. (11891425)
2002
34
Elevated serum lipoprotein(a) level is an independent marker of severity of thoracic aortic atherosclerosis. (12006448)
2002
35
Advances in lipid-lowering therapy in atherosclerosis. (11900401)
2001
36
Tamoxifen effects on endothelial function and cardiovascular risk factors in men with advanced atherosclerosis. (11257075)
2001
37
Potential roles of the peroxisome proliferator-activated receptor-gamma in macrophage biology and atherosclerosis. (11375116)
2001
38
A comparison of lifestyle, genetic, bioclinical and biochemical variables of offspring with and without family histories of premature coronary heart disease: the experience of the European Atherosclerosis Research Studies. (10463146)
1999
39
Low-density lipoprotein particle size is inversely related to plasminogen activator inhibitor-1 levels. The Insulin Resistance Atherosclerosis Study. (10073963)
1999
40
Impaired fasting glucose is not a risk factor for atherosclerosis. (10227566)
1999
41
In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions. (9763539)
1998
42
Low-density lipoprotein apheresis for prevention and regression of atherosclerosis: clinical results. (10225746)
1997
43
Antithrombin and atherosclerosis in the Rotterdam Study. (8673561)
1996
44
Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. (8636537)
1996
45
Secondary preventive potential of lipid-lowering drugs. The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT). (8960446)
1996
46
Molecular variant of angiotensinogen gene is associated with coronary atherosclerosis. (7850980)
1995
47
Inheritability of atherosclerosis and the role of lipoproteins as risk factors in the development of atherosclerosis in WHHL rabbits: risk factors related to coronary atherosclerosis are different from those related to aortic atherosclerosis. (1418101)
1992
48
Aortic atherosclerosis in nonlaying hens with fatty liver syndrome. (6639549)
1983
49
Choroid plexuses in cerebral atherosclerosis (preliminary communication). (7183918)
1982
50
EXPERIMENTAL VASCULAR LATHYRISM AND ITS APPLICATION IN INVESTIGATIONS OF EXPERIMENTAL ATHEROSCLEROSIS. (14139166)
1964

Genetic Variations for Atherosclerosis

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Expression for genes affiliated with Atherosclerosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Atherosclerosis

Search GEO for disease gene expression data for Atherosclerosis.

Pathways for genes affiliated with Atherosclerosis

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Sources:
53Reactome, 29KEGG, 49PharmGKB, 37NCBI BioSystems Database, 12EMD Millipore, 51QIAGEN
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Pathways related to Atherosclerosis according to GeneCards/GeneDecks:

(show all 13)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.8ABCG8, HMGCR, CETP, CEL, ALOX5AP, ALOX5
2
Hide members
11.4CEL, CETP, ABCG8, LPA, APOC2
3
Hide members
11.2APOC2, ABCG8, HMGCR, CETP
411.2CCL2, SAA1, ALOX5AP, ALOX5
5
G-protein signaling Ras family GTPases in kinase cascades (scheme)
Hide members
11.1CCL2, PPARG, MMP3
611.1SELE, MMP3, CCL2
7
Hide members
11.1ALOX5AP, ALOX5, ALOX15
8
Hide members
11.1ALOX5AP, ALOX5, ALOX15
911.1ALOX15, ALOX5, ALOX5AP
1010.9CETP, LPA
11
Hide members
10.9ALOX5, ALOX15
12
Hide members
10.9ALOX5, ALOX5AP
1310.9MSR1, CCL2

Compounds for genes affiliated with Atherosclerosis

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Atherosclerosis according to GeneCards/GeneDecks:

(show top 50)    (show all 119)
idCompoundScoreTop Affiliating Genes
1lipid4414.0ABCG8, HMGCR, MSR1, CETP, CEL, ALOX5AP
2cholesterol44 28 11 2416.8CCL2, MSR1, SELE, CETP, CEL, HMGCR
3simvastatin44 49 59 28 11 2417.9CEL, CETP, SELE, HMGCR, MMP3, LPA
4pravastatin44 49 28 11 2416.5LPA, SELE, CETP, HMGCR, OLR1, MMP3
5phosphatidylcholine4412.5CCL2, LPA, PPARG, ALOX15, SELE, CEL
6heparin44 28 11 2415.4MMP3, SELE, CEL, LPA, HMGCR, ALOX5
7vegf4412.4CCL2, ALOX5, MMP3, LPA, SELE, HMGCR
8nitric oxide44 11 2414.4SELE, MSR1, OLR1, ALOX5AP, ALOX15, LPA
9serine4412.3GJA4, ALOX5, CCL2, CEL, APOC2, MMP3
10fenofibrate44 49 1114.3OLR1, LPA, HMGCR, PPARG, CCL2, CETP
11linoleic acid44 28 2414.3ALOX5, CEL, CETP, OLR1, PPARG, ALOX15
12atorvastatin44 49 28 11 2416.3LPA, SELE, CCL2, PPARG, OLR1, CETP
13aspirin44 49 28 2415.3ALOX5AP, CETP, SELE, HMGCR, LPA, PPARG
14n acetylcysteine4412.2MSR1, HMGCR, MMP3, CCL2, PPARG, SELE
15histamine44 28 2414.2ALOX5AP, SELE, HMGCR, OLR1, MMP3, CCL2
16glucose4412.0MSR1, OLR1, LPA, PPARG, SAA1, APOC2
17phospholipid4412.0OLR1, ABCG8, CETP, ALOX15, APOC2, CEL
18actinomycin d4412.0ALOX5AP, SELE, HMGCR, LPA, CCL2, ESR1
19genistein44 28 59 2 11 2416.9MMP3, SELE, CCL2, ALOX5, ESR1, PPARG
20gemfibrozil44 28 1113.9CETP, HMGCR, LPA, PPARG, APOC2
21cholesterol ester4411.9HMGCR, LPA, MSR1, CETP, CEL
22sulfasalazine44 28 49 1114.9ALOX5, CCL2, MMP3, SELE, PPARG
23arginine4411.8LPA, ALOX5, OLR1, CCL2, CETP, SAA1
24homocysteine44 2412.8SELE, CETP, APOC2, CCL2, LPA
25troglitazone44 28 59 1114.8CCL2, HMGCR, PPARG, SELE, MMP3
26prostacyclin4411.8ALOX5, SELE, PPARG, CCL2, HMGCR
27mk 88659 4412.7ALOX5AP, ALOX5, PPARG, ALOX15
28probucol44 1112.7CETP, CCL2, HMGCR, SELE
29fatty acid4411.6LPA, PPARG, CETP, CEL, APOC2
30niacin44 1112.6LPA, CETP, PPARG, HMGCR
31bezafibrate44 28 1113.6HMGCR, CETP, LPA, PPARG
32ndga4411.6MMP3, PPARG, ALOX5, ALOX5AP
33fluvastatin44 49 28 1114.5SELE, CETP, CCL2, HMGCR
34bw-b 70c5911.5ALOX15, ALOX5, ALOX5AP
35bay-x 10055911.4ALOX5, ALOX15, ALOX5AP
36celecoxib44 59 28 49 11 2416.4MMP3, HMGCR, PPARG, ALOX5
37creatinine4411.4HMGCR, MMP3, LPA, APOC2, SELE
38alpha tocopherol4411.4MSR1, CEL, ALOX5
39fenofibric acid44 2812.4HMGCR, PPARG, CCL2
40losartan44 49 28 1114.4CCL2, PPARG, OLR1, SELE
41cholestyramine4411.4HMGCR, LPA, CETP
42lathosterol44 2412.3HMGCR, ABCG8, CETP
43adma4411.3OLR1, SELE, CCL2
44zileuton59 44 28 1114.3ALOX15, ALOX5AP, ALOX5
45dexamethasone44 49 28 1114.3ALOX5AP, ALOX5, SAA1
46baicalein59 4412.2ALOX5AP, ALOX5, ALOX15
47cycloheximide4411.1ALOX5AP
48pge24411.1ALOX5AP
49rofecoxib44 49 28 1114.0PPARG, MMP3, ALOX5
50gamma-linolenic acid44 2411.8ALOX5, ALOX15, PPARG

GO Terms for genes affiliated with Atherosclerosis

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Sources:
16Gene Ontology
See all sources

Cellular components related to Atherosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557612.1CEL, CCL2, SAA1, APOC2, LPA, PON3
2extracellular spaceGO:00561511.5CCL2, APOC2, PON3, MMP3, SELE, CETP
3low-density lipoprotein particleGO:03436210.9MSR1, APOC2

Biological processes related to Atherosclerosis according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:04428112.5ALOX15, ALOX5, ALOX5AP, CEL, CETP, APOC2
2lipoprotein metabolic processGO:04215711.6LPA, APOC2, CETP, OLR1
3lipoxygenase pathwayGO:01937211.4ALOX5AP, ALOX15, ALOX5
4lipoprotein transportGO:04295311.4APOC2, PPARG, MSR1
5leukotriene metabolic processGO:00669111.4ALOX15, ALOX5, ALOX5AP
6receptor-mediated endocytosisGO:00689811.3LPA, CETP, MSR1
7arachidonic acid metabolic processGO:01936911.3ALOX5AP, ALOX5, ALOX15
8response to drugGO:04249311.3ABCG8, CCL2, APOC2, PPARG
9cholesterol homeostasisGO:04263211.3ABCG8, CETP, APOC2
10response to nutrientGO:00758411.2HMGCR, ABCG8, PPARG
11leukotriene production involved in inflammatory responseGO:00254011.2ALOX5AP, ALOX5
12lipoxin metabolic processGO:200130011.1ALOX5, ALOX5AP
13very-low-density lipoprotein particle remodelingGO:03437211.1CETP, APOC2
14lymphocyte chemotaxisGO:04824711.1SAA1, CCL2
15intestinal cholesterol absorptionGO:03029911.0CEL, ABCG8
16phospholipid transportGO:01591411.0ABCG8, CETP
17inflammatory responseGO:00695410.9ALOX15, SELE, OLR1, CCL2
18macrophage chemotaxisGO:04824610.9CCL2, SAA1
19cholesterol transportGO:03030110.9MSR1, CETP
20negative regulation of macrophage derived foam cell differentiationGO:01074510.8CETP, PPARG

Molecular functions related to Atherosclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cholesterol transporter activityGO:01712710.9CETP, ABCG8
2arachidonic acid bindingGO:05054410.8ALOX5AP, PPARG
3phospholipase bindingGO:04327410.6SELE, APOC2

Products for genes affiliated with Atherosclerosis

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  • Antibodies
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Sources for Atherosclerosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet