MCID: ATP001
MIFTS: 62

Atopic Dermatitis malady

Categories: Skin diseases, Neuronal diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Atopic Dermatitis

Aliases & Descriptions for Atopic Dermatitis:

Name: Atopic Dermatitis 12 25 29 14
Atopic Eczema 12 25 14
Dermatitis, Atopic 42 69
Atopic Neurodermatitis 12
Atopic Dermatitis Nos 12
Allergic Dermatitis 12
Allergic Eczema 12
Besnier's Prurigo 12
Dermatitis Atopic 52
Eczema 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3310
MeSH 42 D003876
UMLS 69 C0011615

Summaries for Atopic Dermatitis

Genetics Home Reference : 25 Atopic dermatitis (also known as atopic eczema) is a disorder characterized by inflammation of the skin (dermatitis). The condition usually begins in early infancy, and it often disappears before adolescence. However, in some affected individuals the condition continues into adulthood or does not begin until adulthood. Hallmarks of atopic dermatitis include dry, itchy skin and red rashes that can come and go. The rashes can occur on any part of the body, although the pattern tends to be different at different ages. In affected infants, the rashes commonly occur on the face, scalp, hands, and feet. In children, the rashes are usually found in the bend of the elbows and knees and on the front of the neck. In adolescents and adults, the rashes typically occur on the wrists, ankles, and eyelids in addition to the bend of the elbows and knees. Scratching the itchy skin can lead to oozing and crusting of the rashes and thickening and hardening (lichenification) of the skin. The itchiness can be so severe as to disturb sleep and impair a person's quality of life.

MalaCards based summary : Atopic Dermatitis, also known as atopic eczema, is related to glucocorticoid resistance and atopic dermatitis 3, and has symptoms including exanthema and pruritus. An important gene associated with Atopic Dermatitis is FAF2 (Fas Associated Factor Family Member 2), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Fluocinonide and Petrolatum have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A dermatitis that is a chronically relapsing inflammatory allergic response located in the skin that causes itching and flaking.

Wikipedia : 71 Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).... more...

Related Diseases for Atopic Dermatitis

Diseases in the Atopic Dermatitis family:

Dermatitis, Atopic 2 Atopic Dermatitis 3
Atopic Dermatitis 4 Atopic Dermatitis 5
Atopic Dermatitis 6 Atopic Dermatitis 7
Atopic Dermatitis 8 Atopic Dermatitis 9

Diseases related to Atopic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 298)
id Related Disease Score Top Affiliating Genes
1 glucocorticoid resistance 29.3 CCL11 IFNG IL13 IL4 IL5 MS4A2
2 atopic dermatitis 3 12.3
3 atopic dermatitis 4 12.2
4 atopic dermatitis 5 12.2
5 atopic dermatitis 6 12.2
6 atopic dermatitis 7 12.2
7 atopic dermatitis 8 12.2
8 atopic dermatitis 9 12.2
9 dermatitis 11.8
10 dermatitis, atopic 2 11.7
11 asthma 11.4
12 eczema herpeticum 11.3
13 allergic rhinitis 11.3
14 netherton syndrome 11.3
15 primary cutaneous amyloidosis 11.2
16 deep dermatophytosis 11.2
17 asthma-related traits 7 11.1
18 asthma 2 11.1
19 asthma susceptibility 5 11.1
20 asthma 1 11.1
21 allergic contact dermatitis of eyelid 10.9
22 asthma-related traits 4 10.9
23 asthma-related traits 3 10.9
24 asthma-related traits 6 10.9
25 pollen allergy 10.9
26 psoriasis 10.6
27 myoglobinuria recurrent 10.4 IFNG IL4
28 atopy 10.4
29 dahlberg borer newcomer syndrome 10.4 IL13 IL5
30 papillary squamous carcinoma 10.4 FLG IL4 IL5
31 crustacean allergy 10.4 IFNG IL13 IL4
32 gastroschisis abdominal wall defects, included 10.3 IFNG IL5
33 oral cavity cancer 10.3 FLG IFNG IL4
34 urethral intrinsic sphincter deficiency 10.3 IFNG IL4 IL5
35 anterior dislocation of lens 10.3 CCL11 IL4 RNASE3
36 isolated klippel-feil syndrome 10.3 IFNG IL4 IL5
37 asymptomatic neurosyphilis 10.3 IFNG IL4
38 marasmus 10.3 IL4 IL5 RNASE3
39 lactose intolerance 10.3 IL13 IL4 IL5
40 lens-induced iridocyclitis 10.3 IL4 IL5 RNASE3
41 askin's tumor 10.3 IL13 IL4 IL5
42 latent syphilis 10.3 CCL11 IL5 RNASE3
43 duodenal somatostatinoma 10.3 IL13 IL4 IL5
44 dissociated nystagmus 10.3 CCL17 IL4 IL5
45 middle lobe syndrome 10.3 CCL17 CCL22 IL5
46 abnormal retinal correspondence 10.3 IFNG IL4 IL5
47 necrotizing gastritis 10.3 CCL11 IL5 RNASE3
48 hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome 10.3 IL31 IL31RA
49 orbit alveolar rhabdomyosarcoma 10.3 IL4 IL5 RNASE3
50 metal allergy 10.3 IL13 IL5 RNASE3

Graphical network of the top 20 diseases related to Atopic Dermatitis:



Diseases related to Atopic Dermatitis

Symptoms & Phenotypes for Atopic Dermatitis

UMLS symptoms related to Atopic Dermatitis:


exanthema, pruritus

MGI Mouse Phenotypes related to Atopic Dermatitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 CCL11 CCL17 IFNG IL13 IL31RA IL4
2 immune system MP:0005387 9.7 CCL11 CCL17 IFNG IL13 IL31RA IL4
3 respiratory system MP:0005388 9.17 TSLP CCL11 IFNG IL13 IL4 IL5

Drugs & Therapeutics for Atopic Dermatitis

Drugs for Atopic Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 387)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluocinonide Approved, Investigational Phase 4 356-12-7 9642
2
Petrolatum Approved Phase 4,Phase 1,Phase 2 8009-03-8
3
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
4
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
5 Sodium thiosulfate Approved Phase 4
6
Desonide Approved, Investigational Phase 4,Phase 3 638-94-8 5311066
7
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
8
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
9
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
10
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 378-44-9 9782
11
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 6447131 17753757
12
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
13
Montelukast Approved Phase 4 158966-92-8 5281040
14
Cortisone acetate Approved Phase 4,Phase 2 1950-04-4, 50-04-4 5745
15
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
16
Cetirizine Approved Phase 4,Phase 3,Phase 2 83881-51-0 2678
17
Levocetirizine Approved Phase 4,Phase 3 130018-77-8
18
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 1 242138-07-4
19
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
20
Glycerol Approved, Experimental Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
21
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
22
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
23
Benzocaine Approved Phase 4,Phase 3,Phase 1,Phase 2 1994-09-7, 94-09-7 2337
24
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
25
Alitretinoin Approved, Investigational Phase 4,Phase 3 5300-03-8 444795
26
Desoximetasone Approved Phase 4 382-67-2 5311067
27
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
28
Glucosamine Approved, Nutraceutical Phase 4 3416-24-8 439213
29 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2
30
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 67-97-0 6221 10883523 5280795
31
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 50-14-6 5280793
32
Tretinoin Approved, Investigational, Nutraceutical Phase 4,Phase 3 302-79-4 5538
33
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
34
decanoic acid Experimental Phase 4,Phase 3,Phase 2 334-48-5 2969
35 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
37 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
38 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
39 Hormones Phase 4,Phase 3,Phase 2,Phase 1
40 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
41 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Emollients Phase 4,Phase 3,Phase 2,Phase 1
43 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
44 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
45 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Antidotes Phase 4
47 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Anti-Infective Agents, Local Phase 4
49 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1
50 Antioxidants Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 709)
id Name Status NCT ID Phase
1 VANOS Cream and Skin Barrier Function Unknown status NCT00819507 Phase 4
2 Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD) Unknown status NCT01781663 Phase 4
3 Effect of Moisturizing Creams on Skin Barrier Function Unknown status NCT00771121 Phase 4
4 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4
5 The Randomized Controlled Clinical Trial of Kushen Injection Unknown status NCT02346318 Phase 4
6 Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis Completed NCT00117377 Phase 4
7 A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis Completed NCT01049243 Phase 4
8 Efficacy and Tolerability of New Topical Formulations in Subjects With Atopic Dermatitis Completed NCT02732314 Phase 4
9 An Efficacy and Safety Study of Tacrolimus Ointment in Adult Participants With Atopic Dermatitis Completed NCT01828879 Phase 4
10 An Efficacy and Safety Study of Tacrolimus Ointment in Pediatric Participants With Atopic Dermatitis Completed NCT01782729 Phase 4
11 Open Label Study of Long Term Treatment of Pediatric Treatment of Atopic Dermatitis With Pimecrolimus Cream 1% Within a Usual Clinical Setting Completed NCT00509990 Phase 4
12 A Comparison Study Between Protopic (Tacrolimus) Ointment and Elidel (Pimecrolimus) Cream in Treating Subjects With Atopic Dermatitis Completed NCT00666302 Phase 4
13 Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects Completed NCT00139581 Phase 4
14 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Treating Pediatric Patients With Atopic Dermatitis Completed NCT00666159 Phase 4
15 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis Completed NCT00667160 Phase 4
16 Evaluation of Cetaphil Advanced Usage to Control Light to Moderate Atopic Dermatitis, in Attempt to Reduce the Necessity of Topic Corticoids Application Completed NCT01063218 Phase 4
17 Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis Completed NCT00121381 Phase 4
18 Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis Completed NCT00693693 Phase 4
19 Protopic Ointment in Children Atopic Eczema Completed NCT00689832 Phase 4
20 Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens Completed NCT00557284 Phase 4
21 Elidel-Study: Elidel in Patients With Atopic Dermatitis Completed NCT00180141 Phase 4
22 Protopic Ointment in Adult Atopic Eczema of the Face Completed NCT00690105 Phase 4
23 Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis Completed NCT00673725 Phase 4
24 A Multi-Center Study of Short and Long-term Use of Protopic Ointment in Patients With Atopic Dermatitis Completed NCT00106496 Phase 4
25 A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis Completed NCT00568412 Phase 4
26 Measuring Adherence to Topical Therapy in Children With Atopic Dermatitis and the Impact of a Return Visit Completed NCT00654355 Phase 4
27 Efficacy of Desonide (Desonatetm) Gel 0.05% in Younger and Older Subjects With Atopic Dermatitis Completed NCT00690833 Phase 4
28 Reconstitution With Pimecrolimus Cream 1% of Steroid-damaged Skin in Adults With Atopic Dermatitis Completed NCT00367393 Phase 4
29 Epiceram™ Device Versus Mid-Strength Topical Steroid (Fluticasone Propionate 0.05%) for Treatment of Atopic Dermatitis Completed NCT00616538 Phase 4
30 Pimecrolimus Cream 1% (Elidel®) and Medicated Device Cream (EletoneTM) in the Treatment and Maintenance of Atopic Dermatitis. Completed NCT01177566 Phase 4
31 Study to Evaluate the Safety and Efficacy of Alefacept (Amevive) in Subjects With Moderate to Severe Atopic Dermatitis Completed NCT00832585 Phase 4
32 Management of Pruritus With Xyzal in Atopic Dermatitis Completed NCT00884325 Phase 4
33 Efficacy and Safety Study of Advantan for Maintenance Treatment of Atopic Dermatitis Completed NCT00185510 Phase 4
34 Epiceram Versus Elidel for Treatment of Mild to Moderate Atopic Dermatitis Completed NCT00460083 Phase 4
35 Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis Completed NCT00130364 Phase 4
36 Analysis of the Quality of Life, the Clinical Effectiveness and Cost-effectiveness of a Novel Educational Programme in Patients With Psoriasis and Atopic Dermatitis Completed NCT01077882 Phase 4
37 A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis Completed NCT00484003 Phase 4
38 Prednisolone vs. Ciclosporine in Severe Atopic Eczema Completed NCT00445081 Phase 4
39 Combination Therapy for Atopic Dermatitis Completed NCT00119158 Phase 4
40 Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients Completed NCT00822783 Phase 4
41 Open-label Study to Investigate Systemic Exposure in Adult and Pediatric Atopic Dermatitis Patients Treated 8.5 Days With Pimecrolimus Cream 1% Under Occlusion Completed NCT00925730 Phase 4
42 A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis Completed NCT01065714 Phase 4
43 Trial on Effectiveness Combined Probiotics in Atopic Dermatitis in Children Completed NCT02519556 Phase 4
44 Safety and Efficacy of Pimecrolimus Cream 1% in Mild to Moderate Head and Neck Atopic Dermatitis (AD) Patients Completed NCT00121316 Phase 4
45 Preventive Treatment of Tacrolimus Ointment in Children With Atopic Dermatitis Completed NCT01745159 Phase 4
46 The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis Completed NCT00179959 Phase 4
47 Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis Completed NCT02589392 Phase 4
48 Effect of Moisturising Creams on Skin Moisture in Atopic Dermatitis Completed NCT00846235 Phase 4
49 Comparison of the Efficacy and Safety of Two Topical Creams for Pediatric Atopic Dermatitis Completed NCT00828412 Phase 4
50 Efficacy and Safety of Pimecrolimus Cream 1% in Patients ≥ 3 Months of Age With Mild or Moderate Atopic Dermatitis Completed NCT00150059 Phase 4

Search NIH Clinical Center for Atopic Dermatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: dermatitis, atopic

Genetic Tests for Atopic Dermatitis

Genetic tests related to Atopic Dermatitis:

id Genetic test Affiliating Genes
1 Dermatitis, Atopic 29

Anatomical Context for Atopic Dermatitis

MalaCards organs/tissues related to Atopic Dermatitis:

39
Skin, T Cells, Testes, Monocytes, Colon, Thymus, B Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Atopic Dermatitis:

18
The Skin

Publications for Atopic Dermatitis

Articles related to Atopic Dermatitis:

(show top 50) (show all 1970)
id Title Authors Year
1
Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis. ( 28219068 )
2017
2
Mother Nature in Eczema: Maternal Factors Influencing Atopic Dermatitis. ( 28523877 )
2017
3
Successful treatment of lichen amyloidosis accompanied by atopic dermatitis by fractional CO2 laser. ( 28535110 )
2017
4
Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency. ( 27886899 )
2017
5
Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies. ( 28057434 )
2017
6
Correlation Between Socioeconomic Status and Atopic Dermatitis in Korean Adults: The Korea National Health and Nutrition Examination Survey (2007-2014). ( 28516452 )
2017
7
Efficacy of hospital inpatient topical treatment for severe adult atopic dermatitis: a retrospective study of 56 patients. ( 28524058 )
2017
8
Weissella cibaria WIKIM28 ameliorates atopic dermatitis-like skin lesions by inducing tolerogenic dendritic cells and regulatory T cells in BALB/c mice. ( 28067304 )
2017
9
Staphylococcus aureus colonization isA associated with increased inhaled corticosteroid requirements in patients with atopic dermatitis and asthma. ( 28526276 )
2017
10
Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis. ( 28526774 )
2017
11
The Natural Course of Atopic Dermatitis and the Association with Asthma. ( 28063089 )
2017
12
Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis. ( 28035398 )
2017
13
Evidence of regulatory myeloid dendritic cells and circulating inflammatory epidermal dendritic cells-like modulated by Toll-like receptors 2 and 7/8 in adults with atopic dermatitis. ( 28083892 )
2017
14
Case Series Study of the Efficacy of Compounded Antibacterial, Steroid, and Moisturizer in Atopic Dermatitis. ( 28523898 )
2017
15
CD1c+ Blood Dendritic Cells in Atopic Dermatitis are Premature and Can Produce Disease-specific Chemokines. ( 27701668 )
2017
16
Targeted Treatment of Atopic Dermatitis. ( 28528610 )
2017
17
Difficult to Manage Atopic Dermatitis. ( 28065338 )
2017
18
Atopic dermatitis in adults: a diagnostic challenge. ( 28071589 )
2017
19
Dietary modifications in atopic dermatitis: patient-reported outcomes. ( 28043181 )
2017
20
Prevalence of filaggrin gene mutations in patients with atopic dermatitis and ichthyosis vulgaris in Kyushu area of Japan and South Korea. ( 28143684 )
2017
21
Atopic dermatitis: Burden of illness, quality of life, and associated complications. ( 28052794 )
2017
22
Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. ( 27304082 )
2017
23
Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis. ( 28524044 )
2017
24
Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood. ( 28531273 )
2017
25
A Mouse Model for Atopic Dermatitis Using Topical Application of Vitamin D3 or of Its Analog MC903. ( 28063040 )
2017
26
Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey. ( 28049449 )
2017
27
Non-invasive evaluation of atopic dermatitis based on redox status using in vivo dynamic nuclear polarization magnetic resonance imaging. ( 28041828 )
2017
28
Filaggrin Mutation in Korean Patients with Atopic Dermatitis. ( 28120571 )
2017
29
Itch intensity in moderate-to-severe plaque psoriasis versus atopic dermatitis: A meta-analysis. ( 28522048 )
2017
30
Effectiveness of regionally-specific immunotherapy for the management of canine atopic dermatitis. ( 28056956 )
2017
31
Parental knowledge, attitude, and behavior toward children with atopic dermatitis. ( 28083974 )
2017
32
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis. ( 28530223 )
2017
33
The Internet for patient education on atopic dermatitis: Friend or foe? ( 28522047 )
2017
34
Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. ( 28049895 )
2017
35
LILRA6 copy number variation correlates with susceptibility to atopic dermatitis. ( 27333811 )
2016
36
Phototherapy for atopic dermatitis. ( 27638440 )
2016
37
SKIN CARE FOR ATOPIC DERMATITIS CHILDREN IN GROUP LIFE. ( 27616169 )
2016
38
Filaggrin gene loss-of-function mutations explain discordance of atopic dermatitis within dizygotic twin pairs. ( 27653621 )
2016
39
Which test is best for diagnosing peanut allergy in South African children with atopic dermatitis? ( 26821907 )
2016
40
Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study. ( 27684861 )
2016
41
As in Atopic Dermatitis, Nonlesional Skin inA Allergic Contact Dermatitis Displays Abnormalities in Barrier Function and Ceramide Content. ( 27826010 )
2016
42
Why we need a harmonized name for atopic dermatitis/atopic eczema/eczema! ( 27624706 )
2016
43
A practical overview of pediatric atopic dermatitis, part 2: triggers and grading. ( 27274543 )
2016
44
Elevated blood eosinophils in early infancy are predictive of atopic dermatitis in children with risk for atopy. ( 27294404 )
2016
45
Aberrant Expression of Bacterial Pattern Recognition Receptor NOD2 of Basophils and Microbicidal Peptides in Atopic Dermatitis. ( 27077833 )
2016
46
Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy. ( 26879860 )
2016
47
Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. ( 27644556 )
2016
48
Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis. ( 27397059 )
2016
49
Increased syndecan-4 expression in sera and skin of patients with atopic dermatitis. ( 27591995 )
2016
50
Vitamin D and antimicrobial peptide levels in patients with atopic dermatitis and atopic dermatitis complicated by eczema herpeticum: AA pilot study. ( 27523434 )
2016

Variations for Atopic Dermatitis

Expression for Atopic Dermatitis

Search GEO for disease gene expression data for Atopic Dermatitis.

Pathways for Atopic Dermatitis

Pathways related to Atopic Dermatitis according to GeneCards Suite gene sharing:

(show all 25)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CCL11 CCL22 FAF2 IFNG IL13 IL31
2
Show member pathways
13.58 CCL11 CCL17 CCL22 CCL27 IFNG IL13
3
Show member pathways
13.45 CCL11 CCL17 CCL22 CCL27 IFNG IL13
4
Show member pathways
13.31 CCL11 CCL17 CCL22 CCL27 IL13 IL4
5
Show member pathways
13.29 CCL11 CCL22 IFNG IL13 IL31 IL31RA
6
Show member pathways
13.21 CCL11 CCL17 CCL22 CCL27 IL13 IL4
7
Show member pathways
12.72 CCL11 IFNG IL13 IL4 IL5 MS4A2
8
Show member pathways
12.21 CCL11 CCL17 IFNG IL13 IL4 IL5
9
Show member pathways
12.15 IFNG IL13 IL4 IL5 TSLP
10
Show member pathways
12.08 IFNG IL13 IL4 IL5
11
Show member pathways
11.95 CCL11 CCL17 CCL22 CCL27
12 11.89 CCL11 CCL22 IL13 IL4
13 11.74 IFNG IL13 IL4 IL5
14
Show member pathways
11.66 IFNG IL4 IL5
15 11.58 CCL11 CCL17 IL4 IL5
16 11.56 CCL11 IL13 IL4 IL5
17 11.56 IFNG IL13 IL4 IL5 TSLP
18 11.45 CCL22 IL13 IL4
19 11.24 IFNG IL4 IL5
20 11.15 IFNG IL13 IL4 IL5
21 11.04 IFNG IL13 IL4 IL5
22 10.93 CCL11 CCL17 CCL22 CCL27 IL13 IL4
23 10.9 CCL11 CCL17 CCL22 IFNG IL13 IL31
24 10.86 IFNG IL13 IL4 IL5 TSLP
25 10.85 IL13 IL4 IL5

GO Terms for Atopic Dermatitis

Cellular components related to Atopic Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.73 CCL11 CCL17 CCL22 CCL27 IFNG IL13
2 external side of plasma membrane GO:0009897 9.55 IFNG IL13 IL31RA IL4 MS4A2
3 extracellular region GO:0005576 9.47 CCL11 CCL17 CCL22 CCL27 FAF2 IFNG
4 epidermal lamellar body GO:0097209 9.26 KLK7 SPINK5

Biological processes related to Atopic Dermatitis according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.92 CCL17 CCL22 CCL27 IL13
2 response to virus GO:0009615 9.79 CCL11 CCL22 IFNG
3 cellular response to interleukin-1 GO:0071347 9.77 CCL11 CCL17 CCL22
4 chemokine-mediated signaling pathway GO:0070098 9.73 CCL11 CCL17 CCL22
5 inflammatory response GO:0006954 9.73 CCL11 CCL17 CCL22 IL13 IL5 MS4A2
6 cellular response to interferon-gamma GO:0071346 9.71 CCL11 CCL17 CCL22
7 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.67 IFNG IL31RA IL4
8 monocyte chemotaxis GO:0002548 9.65 CCL11 CCL17 CCL22
9 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.61 IL31RA IL4
10 positive regulation of B cell proliferation GO:0030890 9.61 IL13 IL4 IL5
11 microglial cell activation GO:0001774 9.6 IL13 IL4
12 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IFNG IL4
13 positive regulation of isotype switching to IgG isotypes GO:0048304 9.58 IFNG IL4
14 positive regulation of mast cell degranulation GO:0043306 9.57 IL13 IL4
15 positive regulation of MHC class II biosynthetic process GO:0045348 9.55 IFNG IL4
16 negative regulation of macrophage activation GO:0043031 9.52 IL31RA IL4
17 positive regulation of immunoglobulin production GO:0002639 9.51 IL13 IL4
18 lymphocyte chemotaxis GO:0048247 9.5 CCL11 CCL17 CCL22
19 regulation of proton transport GO:0010155 9.46 IL13 IL4
20 neutrophil chemotaxis GO:0030593 9.46 CCL11 CCL17 CCL22 IFNG
21 negative regulation of complement-dependent cytotoxicity GO:1903660 9.4 IL13 IL4
22 T-helper 2 cell cytokine production GO:0035745 9.37 IL31RA IL4
23 chemotaxis GO:0006935 9.35 CCL11 CCL17 CCL22 CCL27 IL4
24 immune response GO:0006955 9.28 CCL11 CCL17 CCL22 CCL27 IFNG IL13

Molecular functions related to Atopic Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 CCR chemokine receptor binding GO:0048020 9.33 CCL11 CCL17 CCL22
2 cytokine activity GO:0005125 9.28 CCL11 CCL17 CCL22 IFNG IL13 IL31
3 CCR3 chemokine receptor binding GO:0031728 9.26 CCL11 CCL27
4 chemokine activity GO:0008009 9.26 CCL11 CCL17 CCL22 CCL27

Sources for Atopic Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....