MCID: ATP001
MIFTS: 60

Atopic Dermatitis

Categories: Skin diseases, Neuronal diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Atopic Dermatitis

MalaCards integrated aliases for Atopic Dermatitis:

Name: Atopic Dermatitis 12 25 14
Dermatitis, Atopic 29 42 69
Atopic Eczema 12 25
Atopic Neurodermatitis 12
Atopic Dermatitis Nos 12
Allergic Dermatitis 12
Allergic Eczema 12
Besnier's Prurigo 12
Dermatitis Atopic 52
Eczema 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3310
MeSH 42 D003876
UMLS 69 C0011615

Summaries for Atopic Dermatitis

Genetics Home Reference : 25 Atopic dermatitis (also known as atopic eczema) is a disorder characterized by inflammation of the skin (dermatitis). The condition usually begins in early infancy, and it often disappears before adolescence. However, in some affected individuals the condition continues into adulthood or does not begin until adulthood. Hallmarks of atopic dermatitis include dry, itchy skin and red rashes that can come and go. The rashes can occur on any part of the body, although the pattern tends to be different at different ages. In affected infants, the rashes commonly occur on the face, scalp, hands, and feet. In children, the rashes are usually found in the bend of the elbows and knees and on the front of the neck. In adolescents and adults, the rashes typically occur on the wrists, ankles, and eyelids in addition to the bend of the elbows and knees. Scratching the itchy skin can lead to oozing and crusting of the rashes and thickening and hardening (lichenification) of the skin. The itchiness can be so severe as to disturb sleep and impair a person's quality of life.

MalaCards based summary : Atopic Dermatitis, also known as dermatitis, atopic, is related to lymphoma and malaria, and has symptoms including exanthema and pruritus. An important gene associated with Atopic Dermatitis is FAF2 (Fas Associated Factor Family Member 2), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Montelukast and Petrolatum have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A dermatitis that is a chronically relapsing inflammatory allergic response located in the skin that causes itching and flaking.

Wikipedia : 72 Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).... more...

Related Diseases for Atopic Dermatitis

Diseases in the Atopic Dermatitis family:

Dermatitis, Atopic 2 Atopic Dermatitis 3
Atopic Dermatitis 4 Atopic Dermatitis 5
Atopic Dermatitis 6 Atopic Dermatitis 7
Atopic Dermatitis 8 Atopic Dermatitis 9

Diseases related to Atopic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 313)
id Related Disease Score Top Affiliating Genes
1 lymphoma 30.3 IFNG IL13 IL4 IL5 MS4A2
2 malaria 29.8 CCL11 IFNG IL13 IL4 IL5
3 asthma 28.6 CCL11 CCL17 CCL22 FLG IFNG IL13
4 atopic dermatitis 3 12.3
5 immunodeficiency 11b with atopic dermatitis 12.2
6 atopic dermatitis 4 12.2
7 atopic dermatitis 5 12.2
8 atopic dermatitis 6 12.2
9 atopic dermatitis 7 12.2
10 atopic dermatitis 8 12.2
11 atopic dermatitis 9 12.2
12 dermatitis 11.8
13 dermatitis, atopic 2 11.7
14 netherton syndrome 11.4
15 eczema herpeticum 11.3
16 allergic rhinitis 11.3
17 primary cutaneous amyloidosis 11.2
18 deep dermatophytosis 11.2
19 asthma-related traits 7 11.1
20 asthma 2 11.1
21 asthma susceptibility 5 11.1
22 asthma 1 11.1
23 allergic contact dermatitis of eyelid 11.0
24 myoclonic astatic epilepsy 11.0 IFNG IL4
25 asthma-related traits 4 10.9
26 asthma-related traits 3 10.9
27 asthma-related traits 6 10.9
28 pollen allergy 10.9
29 eye accommodation disease 10.9 IFNG IL4
30 gastroschisis 10.9 IFNG IL5
31 cytoplasmic body myopathy 10.9 IL13 IL5
32 acute vascular insufficiency of intestine 10.8 FLG IFNG IL4
33 goat milk allergy 10.8 IFNG IL13 IL4
34 penis agenesis 10.8 CCL11 IL5
35 orbit alveolar rhabdomyosarcoma 10.8 FLG IL4 IL5
36 aortic arch interruption 10.8 IL13 IL5
37 indian tick typhus 10.8 IFNG IL13
38 myofibroma 10.8 FLG IL13 IL5
39 anterior dislocation of lens 10.8 CCL11 IL4 RNASE3
40 diastrophic dysplasia 10.8 FLG KLK7 SPINK5
41 spermatogenic failure 18 10.8 FLG IL31
42 hypothyroidism due to deficient transcription factors involved in pituitary development or function 10.8 IFNG IL4 IL5
43 acute interstitial pneumonia 10.8 IFNG IL4 SPINK5
44 central sleep apnea 10.8 FLG IFNG IL4
45 myofascial pain syndrome 10.8 CCL11 IL13 IL5
46 thelaziasis 10.7 IFNG IL4
47 abdominal tuberculosis 10.7 IL13 IL4 IL5
48 middle lobe syndrome 10.7 IFNG IL13 IL4
49 papillary follicular thyroid adenocarcinoma 10.7 IL5 RNASE3
50 glucose intolerance 10.7 IL13 IL4 IL5

Graphical network of the top 20 diseases related to Atopic Dermatitis:



Diseases related to Atopic Dermatitis

Symptoms & Phenotypes for Atopic Dermatitis

UMLS symptoms related to Atopic Dermatitis:


exanthema, pruritus

MGI Mouse Phenotypes related to Atopic Dermatitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.93 CCL11 CCL17 IFNG IL13 IL31RA IL4
2 immune system MP:0005387 9.73 CCL11 CCL17 IFNG IL13 IL31RA IL4
3 respiratory system MP:0005388 9.23 IL13 IL4 IL5 PHF11 SOCS3 TSLP

Drugs & Therapeutics for Atopic Dermatitis

Drugs for Atopic Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 386)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Montelukast Approved Phase 4 158966-92-8 5281040
2
Petrolatum Approved Phase 4,Phase 1,Phase 2 8009-03-8
3
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 1 242138-07-4
4
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
5
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
6
Desonide Approved, Investigational Phase 4,Phase 3 638-94-8 5311066
7
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
8
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 378-44-9 9782
9
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
10
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
11
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 6447131 17753757
12
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
13
Fluocinonide Approved, Investigational Phase 4 356-12-7 9642
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
15
Cortisone acetate Approved Phase 4,Phase 2 1950-04-4, 50-04-4 5745
16
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
17
Cetirizine Approved Phase 4,Phase 3,Phase 2 83881-51-0 2678
18
Levocetirizine Approved Phase 4,Phase 3 130018-77-8
19
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
20 Racepinephrine Approved Phase 4,Phase 2
21
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
22
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
23
Benzocaine Approved Phase 4,Phase 3,Phase 1,Phase 2 1994-09-7, 94-09-7 2337
24
Alitretinoin Approved, Investigational Phase 4,Phase 3 5300-03-8 444795
25
Triclosan Approved Phase 4 3380-34-5 5564
26
Desoximetasone Approved Phase 4 382-67-2 5311067
27
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
28
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 1406-16-2
29
Chitosan Approved, Nutraceutical Phase 4,Phase 2 9012-76-4 71853
30
Glucosamine Approved, Nutraceutical Phase 4 3416-24-8 439213
31 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2
32
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 67-97-0 6221 10883523 5280795
33
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 50-14-6 5280793
34
Tretinoin Approved, Investigational, Nutraceutical Phase 4,Phase 3 302-79-4 5538
35
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
36 Parthenolide Investigational Phase 4 20554-84-1
37
BCG vaccine Investigational Phase 4,Phase 3
38
Clobetasol Investigational Phase 4,Phase 3,Phase 2,Phase 1 25122-46-7, 25122-41-2 32798 5311051
39
Lactitol Investigational Phase 4 585-86-4 3871
40 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
42 Hormones Phase 4,Phase 3,Phase 2,Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
44 Leukotriene Antagonists Phase 4
45 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Emollients Phase 4,Phase 3,Phase 2,Phase 1
48 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
50 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 734)

id Name Status NCT ID Phase Drugs
1 Does Treatment With Montelukast Improve Symptoms of Atopic Dermatitis in Children? Unknown status NCT02534467 Phase 4 Montelukast
2 Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD) Unknown status NCT01781663 Phase 4
3 Role of Anti-IgE in Severe Childhood Eczema Unknown status NCT02300701 Phase 4 Xolair;Placebo
4 Effect of Moisturizing Creams on Skin Barrier Function Unknown status NCT00771121 Phase 4 urea/lactic acid;Placebo
5 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4 T.R.U.E. Test Panel 3.2
6 The Randomized Controlled Clinical Trial of Kushen Injection Unknown status NCT02346318 Phase 4 Compound Kushen Injection
7 Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis Completed NCT00117377 Phase 4 Pimecrolimus;Placebo
8 A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis Completed NCT01049243 Phase 4 Fluocinonide Cream 0.1%
9 Open Label Study of Long Term Treatment of Pediatric Treatment of Atopic Dermatitis With Pimecrolimus Cream 1% Within a Usual Clinical Setting Completed NCT00509990 Phase 4 Pimecrolimus
10 Efficacy and Tolerability of New Topical Formulations in Subjects With Atopic Dermatitis Completed NCT02732314 Phase 4 Investigational OTC Cream;0.05% Desonide Cream
11 Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects Completed NCT00139581 Phase 4 Pimecrolimus;Pimecrolimus
12 Study to Evaluate the Safety and Efficacy of Alefacept (Amevive) in Subjects With Moderate to Severe Atopic Dermatitis Completed NCT00832585 Phase 4 Alefacept
13 Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis Completed NCT00693693 Phase 4 hydrocortisone 17-butyrate 0.1% Cream preparation;hydrocortisone 17-butyrate 0.1% Ointment preparation;hydrocortisone 17-butyrate 0.1% Lipocream preparation
14 Bilateral Comparison Study of Elidel 1% and Hylatopic Plus Emollient Foam for the Treatment of Subjects With Atopic Dermatitis Completed NCT01202149 Phase 4
15 Measuring Adherence to Topical Therapy in Children With Atopic Dermatitis and the Impact of a Return Visit Completed NCT00654355 Phase 4 tacrolimus ointment
16 Elidel-Study: Elidel in Patients With Atopic Dermatitis Completed NCT00180141 Phase 4 Elidel-Creme
17 Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens Completed NCT00557284 Phase 4 Montelukast;Placebo
18 Epiceram Versus Elidel for Treatment of Mild to Moderate Atopic Dermatitis Completed NCT00460083 Phase 4 Elidel(R) (pimecrolimus 1%)
19 Combination Therapy for Atopic Dermatitis Completed NCT00119158 Phase 4 Combination of pimecrolimus and fluticasone;pimecrolimus
20 A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis Completed NCT00568412 Phase 4 Elidel
21 Epiceram™ Device Versus Mid-Strength Topical Steroid (Fluticasone Propionate 0.05%) for Treatment of Atopic Dermatitis Completed NCT00616538 Phase 4 Fluticasone Propionate 0.05%
22 Efficacy of Desonide (Desonatetm) Gel 0.05% in Younger and Older Subjects With Atopic Dermatitis Completed NCT00690833 Phase 4 topical desonide hydrogel 0.05%
23 The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis Completed NCT00179959 Phase 4 Sodium hypochlorite (bleach) baths;Mupirocin ointment;Water;Petrolatum Ointment
24 Pimecrolimus Cream 1% (Elidel®) and Medicated Device Cream (EletoneTM) in the Treatment and Maintenance of Atopic Dermatitis. Completed NCT01177566 Phase 4 pimecrolimus
25 Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis Completed NCT00130364 Phase 4 Pimecrolimus;Placebo
26 Management of Pruritus With Xyzal in Atopic Dermatitis Completed NCT00884325 Phase 4 Levocetirizine dihydrochloride (Xyzal);placebo
27 Reconstitution With Pimecrolimus Cream 1% of Steroid-damaged Skin in Adults With Atopic Dermatitis Completed NCT00367393 Phase 4 Pimecrolimus cream 1%
28 Open-label Study to Investigate Systemic Exposure in Adult and Pediatric Atopic Dermatitis Patients Treated 8.5 Days With Pimecrolimus Cream 1% Under Occlusion Completed NCT00925730 Phase 4 Pimecrolimus
29 A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema Completed NCT00576550 Phase 4 Urea;betamethasone valerate;betamethasone valerate
30 Analysis of the Quality of Life, the Clinical Effectiveness and Cost-effectiveness of a Novel Educational Programme in Patients With Psoriasis and Atopic Dermatitis Completed NCT01077882 Phase 4
31 Safety and Efficacy of Pimecrolimus Cream 1% in Mild to Moderate Head and Neck Atopic Dermatitis (AD) Patients Completed NCT00121316 Phase 4 Pimecrolimus;Placebo
32 Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients Completed NCT00822783 Phase 4 Omalizumab;Placebo
33 A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis Completed NCT01065714 Phase 4 Hydrogel vehicle;Eucerin Lotion
34 Trial on Effectiveness Combined Probiotics in Atopic Dermatitis in Children Completed NCT02519556 Phase 4 Probiatop;Placebo
35 A Comparison Study Between Protopic (Tacrolimus) Ointment and Elidel (Pimecrolimus) Cream in Treating Subjects With Atopic Dermatitis Completed NCT00666302 Phase 4 tacrolimus ointment;pimecrolimus cream
36 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Treating Pediatric Patients With Atopic Dermatitis Completed NCT00666159 Phase 4 tacrolimus ointment;pimecrolimus cream
37 Preventive Treatment of Tacrolimus Ointment in Children With Atopic Dermatitis Completed NCT01745159 Phase 4 tacrolimus
38 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis Completed NCT00667160 Phase 4 tacrolimus ointment;pimecrolimus cream
39 Multicenter Clinical Study to Examine the Efficacy and Safety of Zarzenda in Patients With Hand Eczema Completed NCT00488241 Phase 4
40 Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis Completed NCT02589392 Phase 4
41 Comparison of the Efficacy and Safety of Two Topical Creams for Pediatric Atopic Dermatitis Completed NCT00828412 Phase 4 Desonide Cream 0.05%
42 A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis Completed NCT00484003 Phase 4 Pimecrolimus cream 1%
43 VANOS Cream and Skin Barrier Function Completed NCT00819507 Phase 4 Fluocinonide
44 Efficacy and Safety of Pimecrolimus Cream 1% in Patients ≥ 3 Months of Age With Mild or Moderate Atopic Dermatitis Completed NCT00150059 Phase 4 Pimecrolimus Cream 1%
45 Assessment of Pruritus Improvement With Pimecrolimus Treatment on the Areas Affected by Mild-to-moderate AD, in Patients 2- to 11- Year-old Completed NCT00510003 Phase 4 Pimecrolimus
46 Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis Completed NCT01064947 Phase 4 Retapamulin 1%
47 Prednisolone vs. Ciclosporine in Severe Atopic Eczema Completed NCT00445081 Phase 4 Prednisolone;Ciclosporine A
48 Cutivate Lotion HPA Axis Pediatric Study Completed NCT00546000 Phase 4 Fluticasone propionate 0.05% lotion
49 Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis Completed NCT00121381 Phase 4 Pimecrolimus plus topical corticosteroid (TCS);Pimecrolimus vehicle (Placebo) plus topical corticosteroid (TCS)
50 Lactobacillus Rhamnosus GG: Interaction With Human Microbiota and Immunity Completed NCT01148667 Phase 4

Search NIH Clinical Center for Atopic Dermatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: dermatitis, atopic

Genetic Tests for Atopic Dermatitis

Genetic tests related to Atopic Dermatitis:

id Genetic test Affiliating Genes
1 Dermatitis, Atopic 29

Anatomical Context for Atopic Dermatitis

MalaCards organs/tissues related to Atopic Dermatitis:

39
Skin, Testes, T Cells, Colon, Breast, Monocytes, Thymus

Publications for Atopic Dermatitis

Articles related to Atopic Dermatitis:

(show top 50) (show all 2018)
id Title Authors Year
1
Targeted Treatment of Atopic Dermatitis. ( 28528610 )
2017
2
Economic Evaluation of Dupilumab for the Treatment of Moderate-to-Severe Atopic Dermatitis in Adults. ( 28933010 )
2017
3
Evidence of regulatory myeloid dendritic cells and circulating inflammatory epidermal dendritic cells-like modulated by Toll-like receptors 2 and 7/8 in adults with atopic dermatitis. ( 28083892 )
2017
4
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis. ( 28530223 )
2017
5
Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis. ( 28526774 )
2017
6
OBESITY AND ATOPIC DERMATITIS, ALLERGIC RHINITIS. ( 28904285 )
2017
7
CD1c+ Blood Dendritic Cells in Atopic Dermatitis are Premature and Can Produce Disease-specific Chemokines. ( 27701668 )
2017
8
Atopic Dermatitis, The Skin-Disease. ( 28905494 )
2017
9
Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis. ( 28219068 )
2017
10
Haplotype dependent association of rs7927894 (11q13.5) with atopic dermatitis and chronic allergic rhinitis: A study in ECAP cohort. ( 28886043 )
2017
11
Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis. ( 28524044 )
2017
12
Contact allergy to lanolin: temporal changes in prevalence and association with atopic dermatitis. ( 28940210 )
2017
13
Atopic dermatitis: Burden of illness, quality of life, and associated complications. ( 28052794 )
2017
14
Parental knowledge, attitude, and behavior toward children with atopic dermatitis. ( 28083974 )
2017
15
Enhanced expression of genes related to xenobiotic metabolism in the skin of patients with atopic dermatitis but not with ichthyosis vulgaris. ( 28899689 )
2017
16
Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( 28932705 )
2017
17
Elevated fecal calprotectin levels are associated with severity of atopic dermatitis in children. ( 28938841 )
2017
18
Comorbidities of Atopic Dermatitis: Beyond Rhinitis and Asthma. ( 28890845 )
2017
19
Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey. ( 28049449 )
2017
20
Comparison of psoriasis and atopic dermatitis guidelines-an argument for aggressive atopic dermatitis management. ( 28944965 )
2017
21
Two Cases of Successful Treatment of Refractory Chronic Inflammatory Skin Disease, Atopic Dermatitis and Psoriasis with Oral Alitretinoin. ( 28761307 )
2017
22
Family-based whole exome sequencing of atopic dermatitis complicated with cataracts. ( 28938649 )
2017
23
Selected comorbidities of atopic dermatitis: Atopy, neuropsychiatric, and musculoskeletal disorders. ( 28709566 )
2017
24
Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis. ( 28035398 )
2017
25
Scanning indels in the 5q22.1 region and identification of the TMEM232 susceptibility gene that is associated with atopic dermatitis in the Chinese Han population. ( 28351738 )
2017
26
Correlation Between Socioeconomic Status and Atopic Dermatitis in Korean Adults: The Korea National Health and Nutrition Examination Survey (2007-2014). ( 28516452 )
2017
27
The Internet for patient education on atopic dermatitis: Friend or foe? ( 28522047 )
2017
28
Topical ROR inverse agonists suppress inflammation in mouse models of atopic dermatitis and acute irritant dermatitis. ( 28774591 )
2017
29
Case Series Study of the Efficacy of Compounded Antibacterial, Steroid, and Moisturizer in Atopic Dermatitis. ( 28523898 )
2017
30
A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - author response. ( 28940181 )
2017
31
Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. ( 28049895 )
2017
32
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus. ( 28219444 )
2017
33
Atopic dermatitis in adults: a diagnostic challenge. ( 28071589 )
2017
34
A child with kwashiorkor misdiagnosed as atopic dermatitis. ( 28537869 )
2017
35
A Mouse Model of Anaphylaxis and Atopic Dermatitis to Salt-Soluble Wheat Protein Extract. ( 28950276 )
2017
36
The Natural Course of Atopic Dermatitis and the Association with Asthma. ( 28063089 )
2017
37
Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood. ( 28531273 )
2017
38
Primary Cutaneous CD30+ Lymphoproliferative Disorders in a Patient with Severe Atopic Dermatitis: Is There a Causative Link? ( 28952656 )
2017
39
Sensitisation to fungi in atopic dermatitis patients over 14A years of age and the relation to the occurrence of food hypersensitivity reactions. ( 28940850 )
2017
40
Anti-IL-33 Antibody Has a Therapeutic Effect in an Atopic Dermatitis Murine Model Induced by 2, 4-Dinitrochlorobenzene. ( 28952069 )
2017
41
Itch intensity in moderate-to-severe plaque psoriasis versus atopic dermatitis: A meta-analysis. ( 28522048 )
2017
42
Folliculotropic mycosis fungoides associated with atopic dermatitis. ( 28731507 )
2017
43
Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. ( 27304082 )
2017
44
Pilot evaluation of the antipruritic efficacy of a topical transient receptor potential melastatin subfamily 8 (TRPM8) agonist in dogs with atopic dermatitis and pedal pruritus. ( 28952176 )
2017
45
Difficult to Manage Atopic Dermatitis. ( 28065338 )
2017
46
Identification of novel candidate variants including COL6A6 polymorphisms in early-onset atopic dermatitis using whole-exome sequencing. ( 28125976 )
2017
47
Staphylococcus aureus colonization isA associated with increased inhaled corticosteroid requirements in patients with atopic dermatitis and asthma. ( 28526276 )
2017
48
Non-invasive evaluation of atopic dermatitis based on redox status using in vivo dynamic nuclear polarization magnetic resonance imaging. ( 28041828 )
2017
49
Dietary modifications in atopic dermatitis: patient-reported outcomes. ( 28043181 )
2017
50
Effectiveness of regionally-specific immunotherapy for the management of canine atopic dermatitis. ( 28056956 )
2017

Variations for Atopic Dermatitis

Expression for Atopic Dermatitis

Search GEO for disease gene expression data for Atopic Dermatitis.

Pathways for Atopic Dermatitis

Pathways related to Atopic Dermatitis according to GeneCards Suite gene sharing:

(show all 24)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CCL11 CCL22 FAF2 IFNG IL13 IL31
2
Show member pathways
13.59 CCL11 CCL17 CCL22 IFNG IL13 IL4
3
Show member pathways
13.45 CCL11 CCL17 CCL22 IFNG IL13 IL4
4
Show member pathways
13.31 CCL11 CCL22 IFNG IL13 IL31 IL31RA
5
Show member pathways
12.79 CCL11 IFNG IL13 IL4 IL5 MS4A2
6
Show member pathways
12.51 IFNG IL13 IL4 IL5 SOCS3
7
Show member pathways
12.27 CCL11 CCL17 IFNG IL13 IL4 IL5
8
Show member pathways
12.1 IFNG IL13 IL4 IL5 SOCS3
9
Show member pathways
11.97 IFNG IL13 IL4 IL5 SOCS3 TSLP
10 11.93 CCL11 CCL22 IL13 IL4 SOCS3
11 11.77 IFNG IL13 IL4 IL5
12
Show member pathways
11.66 IFNG IL4 IL5
13 11.64 CCL11 IL13 IL4 IL5
14 11.62 IFNG IL13 IL4 IL5 TSLP
15 11.45 CCL22 IL13 IL4
16 11.35 CCL11 CCL17 IL4 IL5 SOCS3
17 11.26 IFNG IL4 IL5
18 11.21 IFNG IL13 IL4 IL5
19 11.11 CCL11 CCL17 CCL22 IL13 IL4 IL5
20 11.08 IFNG IL13 IL4 IL5
21 10.9 CCL11 SOCS3
22 10.9 CCL11 CCL17 CCL22 IFNG IL13 IL31
23 10.88 IL13 IL4 IL5
24 10.86 IFNG IL13 IL4 IL5 TSLP

GO Terms for Atopic Dermatitis

Cellular components related to Atopic Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 CCL11 CCL17 CCL22 IFNG IL13 IL31
2 external side of plasma membrane GO:0009897 9.55 IFNG IL13 IL31RA IL4 MS4A2
3 extracellular region GO:0005576 9.44 CCL11 CCL17 CCL22 FAF2 IFNG IL13
4 epidermal lamellar body GO:0097209 9.26 KLK7 SPINK5

Biological processes related to Atopic Dermatitis according to GeneCards Suite gene sharing:

(show all 23)
id Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.8 CCL11 CCL17 CCL22 IL4
2 response to virus GO:0009615 9.79 CCL11 CCL22 IFNG
3 cellular response to interleukin-1 GO:0071347 9.74 CCL11 CCL17 CCL22
4 chemokine-mediated signaling pathway GO:0070098 9.73 CCL11 CCL17 CCL22
5 inflammatory response GO:0006954 9.73 CCL11 CCL17 CCL22 IL13 IL5 MS4A2
6 cellular response to interferon-gamma GO:0071346 9.69 CCL11 CCL17 CCL22
7 monocyte chemotaxis GO:0002548 9.65 CCL11 CCL17 CCL22
8 positive regulation of B cell proliferation GO:0030890 9.63 IL13 IL4 IL5
9 microglial cell activation GO:0001774 9.61 IL13 IL4
10 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.6 IFNG SOCS3
11 positive regulation of mast cell degranulation GO:0043306 9.59 IL13 IL4
12 positive regulation of isotype switching to IgG isotypes GO:0048304 9.58 IFNG IL4
13 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IFNG IL4
14 immune response GO:0006955 9.56 CCL11 CCL17 CCL22 IFNG IL13 IL4
15 positive regulation of immunoglobulin production GO:0002639 9.55 IL13 IL4
16 negative regulation of macrophage activation GO:0043031 9.54 IL31RA IL4
17 positive regulation of MHC class II biosynthetic process GO:0045348 9.52 IFNG IL4
18 lymphocyte chemotaxis GO:0048247 9.5 CCL11 CCL17 CCL22
19 neutrophil chemotaxis GO:0030593 9.46 CCL11 CCL17 CCL22 IFNG
20 regulation of proton transport GO:0010155 9.43 IL13 IL4
21 negative regulation of complement-dependent cytotoxicity GO:1903660 9.4 IL13 IL4
22 T-helper 2 cell cytokine production GO:0035745 9.37 IL31RA IL4
23 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 8.8 IFNG IL31RA IL4

Molecular functions related to Atopic Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.28 CCL11 CCL17 CCL22 IFNG IL13 IL31
2 chemokine activity GO:0008009 9.13 CCL11 CCL17 CCL22

Sources for Atopic Dermatitis

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