ECD
MCID: ATR001
MIFTS: 52

Atrioventricular Septal Defect (ECD) malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases

Aliases & Classifications for Atrioventricular Septal Defect

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Aliases & Descriptions for Atrioventricular Septal Defect:

Name: Atrioventricular Septal Defect 11 48 24 27 50 13
Atrioventricular Canal Defect 11 27
Endocardial Cushion Defects 39
Endocardial Cushion Defect 11
 
Avcd 11
Avsd 11
Ecd 11

Classifications:



External Ids:

Disease Ontology11 DOID:0050651
ICD1030 Q21.2
ICD9CM32 745.6, 745.60
MeSH39 D004694

Summaries for Atrioventricular Septal Defect

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Disease Ontology:11 A congenital heart septal defect characterized by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum, thus allowing extra blood to circulate the lungs.

MalaCards based summary: Atrioventricular Septal Defect, also known as atrioventricular canal defect, is related to atrioventricular septal defect 5 and atrioventricular septal defect 4. An important gene associated with Atrioventricular Septal Defect is GATA4 (GATA Binding Protein 4), and among its related pathways are Cardiomyocyte Differentiation through BMP Receptors and HOP Signaling. Affiliated tissues include heart, lung and atrioventricular node, and related mouse phenotypes are muscle and respiratory system.

Wikipedia:71 Atrioventricular septal defect (AVSD) or atrioventricular canal defect (AVCD), previously known as... more...

Related Diseases for Atrioventricular Septal Defect

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Diseases in the Atrioventricular Septal Defect family:

Atrioventricular Septal Defect 2 Atrioventricular Septal Defect 3
Atrioventricular Septal Defect 4 Atrioventricular Septal Defect 5

Diseases related to Atrioventricular Septal Defect via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1atrioventricular septal defect 512.4
2atrioventricular septal defect 412.4
3atrioventricular septal defect 212.4
4atrioventricular septal defect 312.4
5double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy12.1
6atrioventricular septal defect with blepharophimosis and anal and radial defects12.0
7complete atrioventricular canal11.5
8partial atrioventricular canal11.4
9ritscher-schinzel syndrome11.3
10right atrial isomerism11.2
11erdheim-chester disease11.2
12ritscher-schinzel syndrome 111.0
13ellis-van creveld syndrome11.0
14atrial septal defect 211.0
153p- syndrome11.0
16hemifacial atrophy, progressive10.9
17tetralogy of fallot10.5
18down syndrome10.4
19right inferior vena cava connecting to left-sided atrium10.2CRELD1, GATA4
20left superior vena cava persisting to left-sided atrium10.2CRELD1, GATA4
21cor triatriatum10.2
22hypertrichotic osteochondrodysplasia cantu type10.2CRELD1, GJA1
23left ventricular outflow tract obstruction10.2
24persistent eustachian valve10.2CRELD1, GATA4, GATA6
25congenital benign spinal muscular atrophy dominant10.2CRELD1, GATA4, GATA6
26pauciarticular chronic arthritis10.1CRELD1, GATA4, GATA6
27pulmonary hypertension10.1
28ventricular septal defect10.1
29atrial septal defect ostium primum10.1
30complete atrioventricular canal-fallot tetralogy syndrome10.1
31complete atrioventricular canal-ventricle hypoplasia syndrome10.1
32complete atrioventricular canal-left heart obstruction syndrome10.1
33hypouricemia, renal, 210.1EVC, EVC2
34skull base neoplasm10.1EDN1, GATA4, GATA6
35heterotaxy10.1
36spondyloepimetaphyseal dysplasia, missouri type10.0EVC, EVC2
37dementia, familial british10.0EVC, EVC2, GJA1
38aortopulmonary window10.0
39cor triatriatum sinister10.0
40transposition of the great arteries10.0
41cleft mitral valve10.0
42acute closed-angle glaucoma10.0EDN1, GATA6, TBX5
43sudden infant death syndrome10.0GJA1, NKX2-5
44cerebritis10.0
45congenital diarrhea 7 with exudative enteropathy9.9GDF1, NKX2-6
46huriez syndrome9.9CRELD1, NKX2-6
47testicular germ cell tumor non-seminomatous9.9CRELD1, GJA1, NKX2-6
48ascending cholangitis9.9GDF1, NKX2-6
49third-degree atrioventricular block9.9GATA4, NKX2-5, TBX5
50endocarditis9.9

Graphical network of the top 20 diseases related to Atrioventricular Septal Defect:



Diseases related to atrioventricular septal defect

Symptoms & Phenotypes for Atrioventricular Septal Defect

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MGI Mouse Phenotypes related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

41 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.3EDN1, GATA4, GATA6, GJA1, NKX2-5, TBX5
2MP:00053888.9GATA4, GATA6, GDF1, GJA1, NKX2-5, NKX2-6
3MP:00053718.7EVC, EVC2, GATA4, GATA6, GJA1, TBX5
4MP:00053858.3EDN1, GATA4, GATA6, GDF1, GJA1, NKX2-5
5MP:00053828.3EDN1, EVC, EVC2, GDF1, GJA1, NKX2-5
6MP:00053808.3EDN1, GATA4, GATA6, GDF1, GJA1, NKX2-5
7MP:00028737.4EDN1, EVC2, GATA4, GATA6, GDF1, GJA1
8MP:00053907.2EDN1, EVC, EVC2, GATA4, GDF1, GJA1
9MP:00053847.1EVC, EVC2, FMO5, GATA4, GATA6, GDF1
10MP:00107686.9EDN1, EVC, EVC2, GATA4, GATA6, GDF1
11MP:00053786.3EDN1, EVC, EVC2, FMO5, GATA4, GATA6

Drugs & Therapeutics for Atrioventricular Septal Defect

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Drugs for Atrioventricular Septal Defect (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Plasma SubstitutesPhase 2240
2AnticoagulantsPhase 22623
3Pharmaceutical SolutionsPhase 28192
4DextransPhase 2104
5Blood SubstitutesPhase 2253
6
Nitric OxideapprovedPhase 161710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
7carnitineNutraceuticalPhase 1162
8
Fentanylapproved, illicit, investigational, vet_approved821437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
1-phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl CII
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
Fentanyl-12
Fentanyl-25
 
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidyl)propionanilide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenethyl-4-(N-propionylanilino)piperidine
N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
9
Acetaminophenapproved1026103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
10
Dexmedetomidineapproved, vet_approved59276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
11
Mechlorethamineapproved39751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
12Hypnotics and Sedatives2616
13Antipyretics1605
14Central Nervous System Depressants13403
15Peripheral Nervous System Agents23689
16Neurotransmitter Agents18340
17Narcotics3646
18Analgesics, Non-Narcotic6501
19Adrenergic alpha-2 Receptor Agonists980
20Adrenergic Agonists3027
21Adrenergic Agents5352
22Adjuvants, Anesthesia1674
23Adrenergic alpha-Agonists1734
24Analgesics11733
25Anesthetics, General2934
26Anesthetics9596
27Analgesics, Opioid3238
28Anesthetics, Intravenous2538

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Study of Triostat in Infants During Heart SurgeryCompletedNCT00027417Phase 3
2Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1, Phase 2
3Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
4Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left VentricleNot yet recruitingNCT03079401Phase 1, Phase 2
5Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowUnknown statusNCT01825369Phase 1
6Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005322
7Measures to Lower the Stress Response in Pediatric Cardiac SurgeryCompletedNCT00848393
8Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005546
9Acetaminophen for Oxidative Stress After Cardiopulmonary BypassCompletedNCT01228305
10National Congenital Heart Disease AuditRecruitingNCT02303535
11The Effect of the Hole in the Cardiac Septum Developed by the MitraClip Procedure on the Blood Flow MechanicsRecruitingNCT02453451
12Evolution of Two Cohorts of Children (Univentricular and Bi-ventricular Heart) After Strapping of the Pulmonary ArteryNot yet recruitingNCT03047343
13Optimal Timing for Repair of Left to Right Shunt LesionsTerminatedNCT00229827
14Infant Weight Gain With Trisomy 21 and CAVCTerminatedNCT00327951
15ADVANCE ASO AMPLATZER™ Atrial Septal Occluder Post Market Surveillance StudyTerminatedNCT02353351

Search NIH Clinical Center for Atrioventricular Septal Defect


Cochrane evidence based reviews: endocardial cushion defects

Genetic Tests for Atrioventricular Septal Defect

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Genetic tests related to Atrioventricular Septal Defect:

id Genetic test Affiliating Genes
1 Atrioventricular Septal Defect27 24 GATA4
2 Atrioventricular Canal Defect27

Anatomical Context for Atrioventricular Septal Defect

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MalaCards organs/tissues related to Atrioventricular Septal Defect:

36
Heart, Lung, Atrioventricular node, Testes

Publications for Atrioventricular Septal Defect

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Articles related to Atrioventricular Septal Defect:

(show top 50)    (show all 410)
idTitleAuthorsYear
1
Early pulmonary arterial hypertension immediately after closure of a ventricular or complete atrioventricular septal defect beyond 6months of age. (27866021)
2017
2
Complete atrioventricular septal defect in the era of prenatal diagnosis. (27981284)
2016
3
Atrioventricular septal defect in an adult patient: There are 'clefts' and clefts. (26947378)
2016
4
Transesophageal echocardiography in an atrioventricular septal defect. (27716686)
2016
5
Complete Atrioventricular Septal Defect with Truncus Arteriosus and Interrupted Aortic Arch in the Fetus. (26910376)
2016
6
Right-Dominant Unbalanced Atrioventricular Septal Defect: Echocardiography in Surgical Decision Making. (27939051)
2016
7
Anesthetic management of a child with complete atrioventricular septal defect and single ventricle posted for noncardiac surgery. (27746571)
2016
8
Expanding the Limits of Posterior Aortic Translocation: Biventricular Correction of Complex Transposition With Complete Atrioventricular Septal Defect and Heterotaxy. (26777936)
2016
9
Shunt Lesions Part I: Patent Ductus Arteriosus, Atrial Septal Defect, Ventricular Septal Defect, and Atrioventricular Septal Defect. (27490614)
2016
10
Surgical repair of a complete atrioventricular septal defect with tetralogy of Fallot using a classical one-patch technique and pulmonary valve preservation. (27681859)
2016
11
Repair of Partial Atrioventricular Septal Defect: Age and Outcomes. (27112649)
2016
12
Cor Triatriatum with Partial Atrioventricular Septal Defect. (27293530)
2016
13
Long-Term Outcome of Patients With Complete Atrioventricular Septal Defect Combined With the Tetralogy of Fallot: Staged Repair Is Not Inferior to PrimaryA Repair. (27692233)
2016
14
Long-term outcomes of reoperations following repair of partial atrioventricular septal defect. (26920940)
2016
15
EP07.07: Atrioventricular septal defect: what can we predict for neonates based on prenatal diagnosisA -A retrospective analysis of 97 cases from a tertiary centre for fetal cardiology. (27647352)
2016
16
Growth Trajectory in Children with Trisomy 21 with and without Atrioventricular Septal Defect. (27237622)
2016
17
Bioinformatic Analysis of Genes and MicroRNAs Associated With Atrioventricular Septal Defect in Down Syndrome Patients. (27396555)
2016
18
The comparative relationships between locations of the papillary muscles and electrophysiologic QRS axis in patients with atrioventricular septal defect and common as opposed to separate orifices in the valve guarding the common atrioventricular junction. (27087659)
2016
19
Echocardiographic Predictors of Left Ventricular Outflow Tract Obstruction following Repair of Atrioventricular Septal Defect. (27834986)
2016
20
A single-centre 37-year experience with reoperation after primary repair of atrioventricular septal defect. (25855593)
2015
21
Atrioventricular septal defect: From embryonic development to long-term follow-up. (26476030)
2015
22
Double orifice tricuspid valve in an infant with partial atrioventricular septal defect. (25684896)
2015
23
Factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of repair of complete atrioventricular septal defect. (26313720)
2015
24
Characterization and quantification of dynamic eccentric regurgitation of the left atrioventricular valve after atrioventricular septal defect correction with 4D Flow cardiovascular magnetic resonance and retrospective valve tracking. (25827288)
2015
25
Complete atrioventricular septal defect and pulmonary stenosis diagnosed in a 49-year-old woman after 10 uneventful births. (25873832)
2015
26
Preoperative NT-proBNP values in patients with atrioventricular septal defect and its role as a predictor of early postoperative course. (26621160)
2015
27
Unique combination of atrioventricular septal defect with cor triatriatum and complete vascular ring. (25870361)
2015
28
Long-term outcomes after surgical repair of complete atrioventricular septal defect. (26048271)
2015
29
Subaortic Area at Risk for Development of Obstruction After Surgical Repair of Atrioventricular Septal Defect: Myth or Reality? (26180156)
2015
30
Anatomical Repair of an Unusual Combination of Tetralogy of Fallot and Atrioventricular Septal Defect With Unroofed Coronary Sinus. (26377366)
2015
31
Disturbed Intracardiac Flow Organization After Atrioventricular Septal Defect Correction as Assessed With 4D Flow Magnetic Resonance Imaging and Quantitative Particle Tracing. (26222698)
2015
32
Modified Single Versus Double-Patch Technique for the Repair of Complete Atrioventricular Septal Defect. (25940208)
2015
33
Persistent 5th aortic arch with coexisting discontinuous pulmonary arteries, double-outlet right ventricle, and complete atrioventricular septal defect. (25873812)
2015
34
Partial atrioventricular septal defect presenting in a septuagenarian. (25994750)
2015
35
Down Syndrome with Complete Atrioventricular Septal Defect, Hypertrophic Cardiomyopathy, and Pulmonary Vein Stenosis. (26504441)
2015
36
Factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of repair of incomplete atrioventricular septal defect. (26107451)
2015
37
A Novel Surgical Technique for Repair of Congenitally Corrected Transposition of the Great Arteries With Atrioventricular Septal Defect: Avoiding Damage to the Conduction System. (26354652)
2015
38
Totally robotic repair of atrioventricular septal defect in the adult. (26545987)
2015
39
Exome sequencing identifies rare variants in multiple genes in atrioventricular septal defect. (25996639)
2015
40
Post-operative left atrioventricular valve function after the staged repair of complete atrioventricular septal defect with tetralogy of Fallot. (24803092)
2014
41
Results of one-and-a-half-patch technique for repair of complete atrioventricular septal defect with a large ventricular component. (24866388)
2014
42
Increased common atrioventricular valve tenting is a risk factor for progression to severe regurgitation in patients with a single ventricle with unbalanced atrioventricular septal defect. (25224553)
2014
43
A single misstep in cardiac development explains the co-occurrence of tetralogy of fallot and complete atrioventricular septal defect in Down syndrome. (24721467)
2014
44
Extracardiac conduit fontan operation and right ventricular exclusion procedure for right ventricle failure after repair of partial atrioventricular septal defect. (25207226)
2014
45
Repair of Complete Atrioventricular Septal Defect in Infants with Down Syndrome: Outcomes and Long-Term Results. (25099029)
2014
46
Left main coronary artery compression syndrome with an incomplete atrioventricular septal defect presenting as angina induced by hyperthyroidism. (25224192)
2014
47
Bosentan treatment for pulmonary arterial hypertension due to complete atrioventricular septal defect in an infant with Down's syndrome. (25465836)
2014
48
Should repair of partial atrioventricular septal defect be delayed until later in childhood? (25017658)
2014
49
Experience with the surgical treatment of atrioventricular septal defect with left ventricular outflow tract obstruction. (24585256)
2014
50
Repair of partial atrioventricular septal defect: a 37-year experience. (25086770)
2014

Variations for Atrioventricular Septal Defect

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Expression for genes affiliated with Atrioventricular Septal Defect

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Search GEO for disease gene expression data for Atrioventricular Septal Defect.

Pathways for genes affiliated with Atrioventricular Septal Defect

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GO Terms for genes affiliated with Atrioventricular Septal Defect

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Cellular components related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor complexGO:00905759.9GATA4, NKX2-5

Biological processes related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1intestinal epithelial cell differentiationGO:006057510.6GATA4, GATA6
2positive regulation of BMP signaling pathwayGO:003051310.6GATA4, GATA6
3cardiac ventricle morphogenesisGO:000320810.6GATA4, NKX2-5
4positive regulation of cardiac muscle cell proliferationGO:006004510.6GATA6, TBX5
5cardiac muscle tissue developmentGO:004873810.6GATA6, NKX2-5
6outflow tract septum morphogenesisGO:000314810.6GATA6, NKX2-5
7bundle of His developmentGO:000316610.6NKX2-5, TBX5
8negative regulation of cardiac muscle cell proliferationGO:006004410.5GJA1, TBX5
9pericardium developmentGO:006003910.4NKX2-6, TBX5
10atrial cardiac muscle cell developmentGO:005501410.4NKX2-5, NKX2-6
11embryonic heart tube developmentGO:003505010.4NKX2-5, NKX2-6
12pharyngeal system developmentGO:006003710.4NKX2-5, NKX2-6
13endocardial cushion developmentGO:000319710.3CRELD1, GATA4, TBX5
14atrial septum morphogenesisGO:006041310.3GATA4, NKX2-5, TBX5
15ventricular cardiac muscle cell developmentGO:005501510.1NKX2-5, NKX2-6
16cardiac muscle cell differentiationGO:005500710.0GATA4, GATA6, NKX2-5, TBX5
17positive regulation of cardioblast differentiationGO:005189110.0GATA4, GATA6, NKX2-5, TBX5
18ventricular septum developmentGO:00032819.9GATA4, TBX5
19cell-cell signalingGO:00072679.8EDN1, GATA4, GJA1, TBX5
20positive regulation of transcription, DNA-templatedGO:00458939.7GATA4, GATA6, NKX2-5, TBX5
21positive regulation of transcription from RNA polymerase II promoterGO:00459449.5EDN1, GATA4, GATA6, NKX2-5, TBX5
22heart developmentGO:00075079.3EDN1, GJA1, NKX2-5, NKX2-6, TBX5

Molecular functions related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II regulatory region sequence-specific DNA bindingGO:000097710.3GATA4, GATA6, TBX5
2transcription regulatory region DNA bindingGO:004421210.1GATA4, GATA6, NKX2-5
3transcription factor bindingGO:00081349.9GATA4, GATA6, NKX2-5, TBX5
4sequence-specific DNA bindingGO:00435659.5GATA4, GATA6, NKX2-5, NKX2-6, TBX5
5transcription factor activity, sequence-specific DNA bindingGO:00037009.5GATA4, GATA6, NKX2-5, NKX2-6, TBX5
6transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012289.2GATA4, GATA6, NKX2-5, TBX5

Sources for Atrioventricular Septal Defect

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet