MCID: ATR001
MIFTS: 52

Atrioventricular Septal Defect malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases

Aliases & Classifications for Atrioventricular Septal Defect

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Aliases & Descriptions for Atrioventricular Septal Defect:

Name: Atrioventricular Septal Defect 11 46 23 13 25 48
Atrioventricular Canal Defect 11 25
Endocardial Cushion Defects 37
Endocardial Cushion Defect 11
 
Avcd 11
Avsd 11
Ecd 11

Classifications:



External Ids:

Disease Ontology11 DOID:0050651
ICD1028 Q21.2
ICD9CM30 745.6, 745.60
MeSH37 D004694
UMLS66 C0014116

Summaries for Atrioventricular Septal Defect

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Disease Ontology:11 A congenital heart septal defect characterized by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum, thus allowing extra blood to circulate the lungs.

MalaCards based summary: Atrioventricular Septal Defect, also known as atrioventricular canal defect, is related to atrioventricular septal defect 4 and atrioventricular septal defect 5. An important gene associated with Atrioventricular Septal Defect is GATA4 (GATA Binding Protein 4), and among its related pathways are Physiological and Pathological Hypertrophy of the Heart and HOP Signaling. Affiliated tissues include heart, lung and atrioventricular node, and related mouse phenotypes are craniofacial and respiratory system.

Wikipedia:69 Atrioventricular septal defect (AVSD) or atrioventricular canal defect (AVCD), previously known as... more...

Related Diseases for Atrioventricular Septal Defect

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Diseases in the Atrioventricular Septal Defect family:

Atrioventricular Septal Defect 2 Atrioventricular Septal Defect 3
Atrioventricular Septal Defect 4 Atrioventricular Septal Defect 5

Diseases related to Atrioventricular Septal Defect via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1atrioventricular septal defect 412.4
2atrioventricular septal defect 512.4
3atrioventricular septal defect 212.4
4atrioventricular septal defect 312.4
5double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy12.2
6atrioventricular septal defect with blepharophimosis and anal and radial defects12.2
7complete atrioventricular canal11.6
8partial atrioventricular canal11.5
9ritscher-schinzel syndrome11.4
10erdheim-chester disease11.3
11tetralogy of fallot10.6
12univentricular heart with single atrio-ventricular valve10.6CRELD1, GATA4
13azygos continuation of the inferior vena cava10.6CRELD1, GATA4
14down syndrome10.5
15straddling and/or overriding mitral valve10.3CRELD1, GATA4, GATA6
16cor triatriatum10.3
17partial duplication of the short arm of chromosome x10.3CRELD1, GATA4, GATA6
18primary lateral sclerosis, adult, 110.3EVC, EVC2
19pulmonary hypertension10.3
20left ventricular outflow tract obstruction10.3
21huriez syndrome10.3CRELD1, NKX2-6
22uniparental disomy of chromosome 1110.2EDN1, GATA6
23right atrial isomerism10.2
24atrial septal defect ostium primum10.2
25complete atrioventricular canal-fallot tetralogy syndrome10.2
26complete atrioventricular canal-ventricle hypoplasia syndrome10.2
27complete atrioventricular canal-left heart obstruction syndrome10.2
28ventricular septal defect10.2
29chromosomal deletion syndrome10.2EVC, EVC2
30suppurative cholangitis10.2GDF1, NKX2-6
31heterotaxy10.2
32childhood parosteal osteogenic sarcoma10.1CRELD1, NKX2-6
33aortopulmonary window10.1
34cor triatriatum sinister10.1
35transposition of the great arteries10.1
36cleft mitral valve10.1
37cerebritis10.1
3846 xy gonadal dysgenesis10.1EDN1, GJA1
39ellis-van creveld syndrome10.1
40atrial septal defect 210.1
413p- syndrome10.1
42testicular trophoblastic tumor10.1CRELD1, GJA1, NKX2-6
43dementia, familial british10.1EVC, EVC2, GJA1
44pituitary adenoma10.0EDN1, GATA4, GATA6
45endocarditis10.0
46polydactyly10.0
47vascular disease10.0
48discrete subaortic stenosis10.0
49dextrocardia10.0
50double outlet right atrium10.0

Graphical network of the top 20 diseases related to Atrioventricular Septal Defect:



Diseases related to atrioventricular septal defect

Symptoms for Atrioventricular Septal Defect

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Drugs & Therapeutics for Atrioventricular Septal Defect

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Drugs for Atrioventricular Septal Defect (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Nitric OxidePhase 158510102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
2carnitineNutraceuticalPhase 1152
3
Fentanyl739437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
 
Fentanyl-12
Fentanyl-25
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
4
Dexmedetomidine51576631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
5
Acetaminophen930103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetaminophene
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
 
Momentum
Mono Praecimed
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxyacetanilide
p-hydroxyphenolacetamide
6
Mechlorethamine36351-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine

Interventional clinical trials:

(show all 13)
idNameStatusNCT IDPhase
1Study of Triostat in Infants During Heart SurgeryCompletedNCT00027417Phase 3
2Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1, Phase 2
3Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
4Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowRecruitingNCT01825369Phase 1
5Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005322
6Measures to Lower the Stress Response in Pediatric Cardiac SurgeryCompletedNCT00848393
7Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005546
8National Congenital Heart Disease AuditRecruitingNCT02303535
9Acetaminophen for Oxidative Stress After Cardiopulmonary BypassRecruitingNCT01228305
10The Effect of the Hole in the Cardiac Septum Developed by the MitraClip Procedure on the Blood Flow MechanicsRecruitingNCT02453451
11ADVANCE ASO AMPLATZER™ Atrial Septal Occluder Post Market Surveillance StudyRecruitingNCT02353351
12Optimal Timing for Repair of Left to Right Shunt LesionsTerminatedNCT00229827
13Infant Weight Gain With Trisomy 21 and CAVCTerminatedNCT00327951

Search NIH Clinical Center for Atrioventricular Septal Defect


Cochrane evidence based reviews: endocardial cushion defects

Genetic Tests for Atrioventricular Septal Defect

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Genetic tests related to Atrioventricular Septal Defect:

id Genetic test Affiliating Genes
1 Atrioventricular Septal Defect25 23 GATA4
2 Atrioventricular Canal Defect25

Anatomical Context for Atrioventricular Septal Defect

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MalaCards organs/tissues related to Atrioventricular Septal Defect:

34
Heart, Lung, Atrioventricular node, Testes

Animal Models for Atrioventricular Septal Defect or affiliated genes

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MGI Mouse Phenotypes related to Atrioventricular Septal Defect:

39 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.4EDN1, EVC, EVC2, GDF1, GJA1, NKX2-5
2MP:00053888.4GATA4, GATA6, GDF1, GJA1, NKX2-5, NKX2-6
3MP:00053698.0EDN1, GATA4, GATA6, GJA1, NKX2-5, TBX5
4MP:00053717.7EVC, EVC2, GATA4, GATA6, GJA1, TBX5
5MP:00053907.5EDN1, EVC, EVC2, GATA4, GDF1, GJA1
6MP:00053847.1EVC, EVC2, FMO5, GATA4, GATA6, GDF1
7MP:00053807.0EDN1, GATA4, GATA6, GDF1, GJA1, NKX2-5
8MP:00053856.8EDN1, GATA4, GATA6, GDF1, GJA1, NKX2-5
9MP:00028736.5EDN1, EVC2, GATA4, GATA6, GDF1, GJA1
10MP:00107686.1EDN1, EVC, EVC2, GATA4, GATA6, GDF1
11MP:00053785.4EDN1, EVC, EVC2, FMO5, GATA4, GATA6

Publications for Atrioventricular Septal Defect

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Articles related to Atrioventricular Septal Defect:

(show top 50)    (show all 402)
idTitleAuthorsYear
1
EP07.07: Atrioventricular septal defect: what can we predict for neonates based on prenatal diagnosisA -A retrospective analysis of 97 cases from a tertiary centre for fetal cardiology. (27647352)
2016
2
Expanding the Limits of Posterior Aortic Translocation: Biventricular Correction of Complex Transposition With Complete Atrioventricular Septal Defect and Heterotaxy. (26777936)
2016
3
Repair of Partial Atrioventricular Septal Defect: Age and Outcomes. (27112649)
2016
4
Subaortic Area at Risk for Development of Obstruction After Surgical Repair of Atrioventricular Septal Defect: Myth or Reality? (26180156)
2015
5
Characterization and quantification of dynamic eccentric regurgitation of the left atrioventricular valve after atrioventricular septal defect correction with 4D Flow cardiovascular magnetic resonance and retrospective valve tracking. (25827288)
2015
6
Persistent 5th aortic arch with coexisting discontinuous pulmonary arteries, double-outlet right ventricle, and complete atrioventricular septal defect. (25873812)
2015
7
Partial atrioventricular septal defect presenting in a septuagenarian. (25994750)
2015
8
Exome sequencing identifies rare variants in multiple genes in atrioventricular septal defect. (25996639)
2015
9
Stunned atrioventricular node from left ventricular angiography in a patient with repaired atrioventricular septal defect. (23052672)
2013
10
8p23.1 duplication detected by array-CGH with complete atrioventricular septal defect and unilateral hand preaxial hexadactyly. (23404914)
2013
11
Unbalanced atrioventricular septal defect: defining the limits of biventricular repair. (23561815)
2013
12
Results of simplified single-patch repair for complete atrioventricular septal defect. (23598584)
2013
13
Outcome after repair of atrioventricular septal defect with tetralogy of Fallot. (21855095)
2012
14
Anatomical repair of double outlet right ventricle associated with complete atrioventricular septal defect and pulmonary stenosis: extending the indications for aortic translocation. (22364399)
2012
15
Surgical management of complete atrioventricular septal defect: associations with surgical technique, age, and trisomy 21. (21163497)
2011
16
Left ventricular outflow tract obstruction after the modified single patch repair of atrioventricular septal defects: teasing fact from fiction. (20338382)
2010
17
Partial and transitional atrioventricular septal defect outcomes. (20103337)
2010
18
Reoperations after repair of partial atrioventricular septal defect: a 45-year single-center experience. (20417744)
2010
19
Routine leaflet augmentation of left atrioventricular valve in the repair of atrioventricular septal defect. (23960576)
2009
20
What is the optimal time to repair atrioventricular septal defect and common atrioventricular valvar orifice? (17572926)
2007
21
Long-term survival with partial atrioventricular septal defect. (17137654)
2007
22
Primary surgical correction of transposition of the great arteries and atrioventricular septal defect associated with left isomerism. (16391973)
2006
23
Mosaic trisomy 6 and maternal uniparental disomy 6 in a 23-week gestation fetus with atrioventricular septal defect. (16470696)
2006
24
Atrioventricular septal defect with intact septal structures presenting as left atrioventricular valvar insufficiency. (16454887)
2006
25
Poor sensitivity of routine fetal anomaly ultrasound screening for antenatal detection of atrioventricular septal defect. (15253968)
2004
26
Left atrioventricular valve regurgitation after repair of incomplete atrioventricular septal defect. (15172287)
2004
27
Single-stage repair of complete atrioventricular septal defect and coarctation of the aorta in neonate. (15384714)
2004
28
Atrioventricular septal defect associated with type A postaxial polydactyly. (15691417)
2004
29
Missense mutations in CRELD1 are associated with cardiac atrioventricular septal defects. (12632326)
2003
30
Incomplete atrioventricular septal defect with hypoplastic left ventricle and left atrioventricular valve stenosis. (11355259)
2001
31
Transthoracic three-dimensional echocardiography in the preoperative assessment of atrioventricular septal defect morphology. (11078279)
2000
32
Atrioventricular septal defect in the fetus. (10561654)
1999
33
Complete atrioventricular septal defect and Ebstein's anomaly. (10089255)
1999
34
Left ventricular outflow tract obstruction after partial atrioventricular septal defect repair. (10585048)
1999
35
Atrioventricular septal defect with tetralogy of Fallot: results of surgical correction. (9930496)
1998
36
Size of ventricular structures influences surgical outcome in Down syndrome infants with atrioventricular septal defect. (9576172)
1998
37
Amrinone versus dopamine-nitroglycerin after reconstructive surgery for complete atrioventricular septal defect. (9412887)
1997
38
Anatomically sound, simplified approach to repair of "complete" atrioventricular septal defect. (9262599)
1997
39
Ten-year experience with surgical treatment of partial atrioventricular septal defect: risk factors in the early postoperative period. (8691859)
1996
40
Transatrial-transpulmonary repair of atrioventricular septal defect with right ventricular outflow tract obstruction. (8286866)
1993
41
Atypical form of atrioventricular septal defect without left axis deviation: relation between morphology and unusual QRS axis. (8038031)
1993
42
The concept and definition of an "intermediate form" of atrioventricular septal defect. (1789868)
1991
43
Complete repair of atrioventricular septal defect. (2069458)
1991
44
Cross-sectional echocardiography in the diagnosis of atrioventricular septal defect. (2365528)
1990
45
Repair of complete atrioventricular septal defect with tetralogy of Fallot. (2400260)
1990
46
Valve insufficiency after atrioventricular septal defect repair: differences between patients with and without Down's syndrome? (2146928)
1990
47
Atrioventricular septal defect with intact septal structures in a 74-year-old. (2312206)
1990
48
Optimal management of patients with complete atrioventricular septal defect. (2466596)
1989
49
Ostium primum atrioventricular septal defect: an anatomical and surgical review. (3963928)
1986
50
Left atrioventricular valve in atrioventricular septal defect. (6711449)
1984

Variations for Atrioventricular Septal Defect

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Expression for genes affiliated with Atrioventricular Septal Defect

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Search GEO for disease gene expression data for Atrioventricular Septal Defect.

Pathways for genes affiliated with Atrioventricular Septal Defect

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GO Terms for genes affiliated with Atrioventricular Septal Defect

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Cellular components related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor complexGO:00905759.6GATA4, NKX2-5

Biological processes related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1intestinal epithelial cell differentiationGO:006057510.5GATA4, GATA6
2positive regulation of BMP signaling pathwayGO:003051310.4GATA4, GATA6
3outflow tract septum morphogenesisGO:000314810.2GATA6, NKX2-5
4blood vessel morphogenesisGO:004851410.1EDN1, GJA1
5adult heart developmentGO:000751210.1GJA1, NKX2-5
6cardiac muscle tissue developmentGO:004873810.1GATA6, NKX2-5
7atrial cardiac muscle cell developmentGO:005501410.0NKX2-5, NKX2-6
8pharyngeal system developmentGO:006003710.0NKX2-5, NKX2-6
9negative regulation of cardiac muscle cell proliferationGO:006004410.0GJA1, TBX5
10cell developmentGO:004846810.0GATA4, GATA6, GDF1
11transdifferentiationGO:006029010.0GATA4, TBX5
12positive regulation of cardiac muscle cell proliferationGO:00600459.9GATA6, TBX5
13cardiac ventricle morphogenesisGO:00032089.9GATA4, NKX2-5
14ventricular cardiac muscle cell developmentGO:00550159.9NKX2-5, NKX2-6
15in utero embryonic developmentGO:00017019.8EDN1, GATA6, GJA1
16pericardium developmentGO:00600399.7NKX2-6, TBX5
17bundle of His developmentGO:00031669.7NKX2-5, TBX5
18endocardial cushion developmentGO:00031979.6CRELD1, GATA4, TBX5
19ventricular septum developmentGO:00032819.6GATA4, TBX5
20heart loopingGO:00019479.6GATA4, GJA1, NKX2-5
21embryonic heart tube developmentGO:00350509.5GJA1, NKX2-5, NKX2-6
22atrial septum morphogenesisGO:00604139.2GATA4, NKX2-5, TBX5
23positive regulation of cardioblast differentiationGO:00518919.1GATA4, GATA6, NKX2-5, TBX5
24cardiac muscle cell differentiationGO:00550079.1GATA4, GATA6, NKX2-5, TBX5
25cell-cell signalingGO:00072678.9EDN1, GATA4, GJA1, TBX5
26positive regulation of transcription, DNA-templatedGO:00458938.6GATA4, GATA6, NKX2-5, TBX5
27positive regulation of transcription from RNA polymerase II promoterGO:00459448.0EDN1, GATA4, GATA6, NKX2-5, TBX5
28heart developmentGO:00075077.6EDN1, GJA1, NKX2-5, NKX2-6, TBX5

Molecular functions related to Atrioventricular Septal Defect according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region DNA bindingGO:00442129.6GATA4, GATA6, NKX2-5
2RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009779.2GATA4, GATA6, TBX5
3transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012288.7GATA4, GATA6, NKX2-5, TBX5
4transcription factor bindingGO:00081348.2GATA4, GATA6, NKX2-5, TBX5
5transcription factor activity, sequence-specific DNA bindingGO:00037008.0GATA4, GATA6, NKX2-5, NKX2-6, TBX5
6sequence-specific DNA bindingGO:00435657.9GATA4, GATA6, NKX2-5, NKX2-6, TBX5

Sources for Atrioventricular Septal Defect

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet