Aliases & Classifications for Atrophic Rhinitis

MalaCards integrated aliases for Atrophic Rhinitis:

Name: Atrophic Rhinitis 12 14
Rhinitis, Atrophic 12 41 69
Rhinitis Sicca 12 69
Ozena 12 69
Dry Rhinitis 12
Ozaena 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4731
MeSH 41 D012222
SNOMED-CT 64 28111002

Summaries for Atrophic Rhinitis

Disease Ontology : 12 A rhinitis which involves inflammation of the nose characterised by atrophy of nasal mucosa including the glands, turbinate bones, and the nerve elements supplying the nose that is caused by heredity factors, endocrine imbalance, nutritional deficiency, bacterial infection and autoimmune issues.

MalaCards based summary : Atrophic Rhinitis, also known as rhinitis, atrophic, is related to rhinitis and actinobacillosis, and has symptoms including rhinorrhea An important gene associated with Atrophic Rhinitis is XPNPEP2 (X-Prolyl Aminopeptidase 2), and among its related pathways/superpathways is MHC class II antigen presentation. The drugs Acetylcholine and abobotulinumtoxinA have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and thyroid.

Related Diseases for Atrophic Rhinitis

Diseases related to Atrophic Rhinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 rhinitis 11.1
2 actinobacillosis 11.1
3 pneumonia 10.5
4 ectodermal dysplasia 10.2
5 pleuropneumonia 10.1
6 blood group, i system 10.0
7 mucositis 10.0
8 osteoporosis 9.8
9 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 9.8
10 leprosy 3 9.8
11 aging 9.8
12 mycobacterium tuberculosis 1 9.8
13 bone mineral density quantitative trait locus 8 9.8
14 glass syndrome 9.8
15 bone mineral density quantitative trait locus 15 9.8
16 cerebellofaciodental syndrome 9.8
17 nasopharyngitis 9.8
18 lepromatous leprosy 9.8
19 brucellosis 9.8
20 myiasis 9.8
21 rhinoscleroma 9.8
22 diphtheria 9.8
23 typhoid fever 9.8
24 hypothyroidism 9.8
25 iron metabolism disease 9.8
26 vasomotor rhinitis 9.8
27 thyroiditis 9.8
28 dacryocystitis 9.8

Graphical network of the top 20 diseases related to Atrophic Rhinitis:



Diseases related to Atrophic Rhinitis

Symptoms & Phenotypes for Atrophic Rhinitis

UMLS symptoms related to Atrophic Rhinitis:


rhinorrhea

Drugs & Therapeutics for Atrophic Rhinitis

Drugs for Atrophic Rhinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 1, Phase 2 51-84-3 187
2 abobotulinumtoxinA Phase 1, Phase 2
3 Botulinum Toxins Phase 1, Phase 2
4 Botulinum Toxins, Type A Phase 1, Phase 2
5 Cholinergic Agents Phase 1, Phase 2
6 Neuromuscular Agents Phase 1, Phase 2
7 Neurotransmitter Agents Phase 1, Phase 2
8 onabotulinumtoxinA Phase 1, Phase 2
9 Peripheral Nervous System Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome Terminated NCT00732680 Phase 1, Phase 2 Botulinum Toxin Type A
2 A Clinical Study to Evaluate the Safety and Efficacy of Platelet Rich Plasma Injection for Atrophic Rhinitis Recruiting NCT03112330
3 Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps Active, not recruiting NCT02855931
4 Gore Tex Implants in the Treatment of Atrophic Rhinitis Suspended NCT00832403
5 Topical Antibiotic Use In Chronic Rhinosinusitis A Double-Blinded, Randomized, Placebo Controlled Study Withdrawn NCT00669799 gentamyacin;gentamyacin

Search NIH Clinical Center for Atrophic Rhinitis

Cochrane evidence based reviews: rhinitis, atrophic

Genetic Tests for Atrophic Rhinitis

Anatomical Context for Atrophic Rhinitis

MalaCards organs/tissues related to Atrophic Rhinitis:

38
Bone, Testes, Thyroid, Liver, Colon

Publications for Atrophic Rhinitis

Articles related to Atrophic Rhinitis:

(show top 50) (show all 374)
# Title Authors Year
1
Role of Histopathology in Differentiating Primary Atrophic Rhinitis from Atrophic Stage of Rhinoscleroma. ( 28239581 )
2017
2
Successful management of primary atrophic rhinitis by turbinate reconstruction using autologous costal cartilage. ( 28669540 )
2017
3
Is submucosal fat injection effective in atrophic rhinitis? An experimental animal study. ( 28707085 )
2017
4
Empty nose syndrome and atrophic rhinitis. ( 27613452 )
2016
5
Atrophic rhinitis caused by Cedecea davisae with accompanying mucocele. ( 26211869 )
2015
6
Surfactant protein a expression in chronic rhinosinusitis and atrophic rhinitis. ( 25992168 )
2015
7
Complete Genome Sequence of Bordetella bronchiseptica S798, an Isolate from a Pig with Atrophic Rhinitis. ( 24831150 )
2014
8
Immunologic study and optimization of Salmonella delivery strains expressing adhesin and toxin antigens for protection against progressive atrophic rhinitis in a murine model. ( 25355999 )
2014
9
Generation of an attenuated Salmonella-delivery strains expressing adhesin and toxin antigens for progressive atrophic rhinitis, and evaluation of its immune responses in a murine model. ( 25045826 )
2014
10
New regenerative approach to atrophic rhinitis using autologous lipoaspirate transfer and platelet-rich plasma in five patients: Our Experience. ( 24938860 )
2014
11
Atrophic rhinitis presenting with ethmoidal mucocele: a case report. ( 25121010 )
2014
12
Chronic rhinosinusitis in ex-lepromatous leprosy patients with atrophic rhinitis. ( 23398842 )
2013
13
Atrophic rhinitis. ( 23484896 )
2013
14
Acute Exacerbation of Chronic Rhinosinusitis (AECRS) with Orbital Complications in an Atrophic Rhinitis Patient: A Mere Co-incidence? ( 24551696 )
2013
15
Primary atrophic rhinitis: a clinical profile, microbiological and radiological study. ( 23762613 )
2012
16
Swine atrophic rhinitis caused by pasteurella multocida toxin and bordetella dermonecrotic toxin. ( 22411430 )
2012
17
Chemosensory function assessed with psychophysical testing and event-related potentials in patients with atrophic rhinitis. ( 21717190 )
2012
18
Interventions for atrophic rhinitis. ( 22336840 )
2012
19
Rhinoplasty in atrophic rhinitis. ( 23025225 )
2012
20
Anhidrotic ectodermal dysplasia presenting as atrophic rhinitis. ( 22666945 )
2011
21
Study of histopathological changes in primary atrophic rhinitis. ( 23724252 )
2011
22
A report on a rare case of Klebsiella ozaenae causing atrophic rhinitis in the UK. ( 22669526 )
2011
23
Use of computer snout morphometry in atrophic rhinitis monitoring. ( 21498219 )
2011
24
Rhinitis sicca, dry nose and atrophic rhinitis: a review of the literature. ( 20878413 )
2011
25
A new technique for nasal stent fabrication for atrophic rhinitis: a clinical report. ( 21585589 )
2011
26
Primary atrophic rhinitis. ( 20869578 )
2010
27
Hypohidrotic ectodermal dysplasia with atrophic rhinitis and nasal myiasis. ( 19616858 )
2009
28
Microbiological study of role of fungi in primary atrophic rhinitis. ( 18926001 )
2009
29
Efficacy of a novel Pasteurella multocida vaccine against progressive atrophic rhinitis of swine. ( 19428902 )
2009
30
Chitosan microspheres containing Bordetella bronchiseptica antigens as novel vaccine against atrophic rhinitis in pigs. ( 18600065 )
2008
31
Prosthetic management of atrophic rhinitis. ( 23120587 )
2008
32
Novel treatment of atrophic rhinitis: early results. ( 18317788 )
2008
33
Atrophic rhinitis vaccine composition triggers different serological profiles that do not correlate with protection. ( 18401954 )
2008
34
Atrophic rhinitis: a CFD study of air conditioning in the nasal cavity. ( 17569762 )
2007
35
On the risk of carcinomatous change in atrophic rhinitis. ( 17156518 )
2007
36
Rhinoplasty and young's operation in atrophic rhinitis. ( 23120345 )
2006
37
Immunogenicity and efficacy of three recombinant subunit Pasteurella multocida toxin vaccines against progressive atrophic rhinitis in pigs. ( 16122849 )
2006
38
Light and electron microscopic study of primary atrophic rhinitis mucosa. ( 17063751 )
2006
39
Interesting observations on Primary Atrophic Rhinitis. ( 23120308 )
2006
40
Radiology quiz case 4: primary atrophic rhinitis, or ozena. ( 16103316 )
2005
41
Pre-cancerous changes in the nasal mucosa of atrophic rhinitis: A preliminary report. ( 23120119 )
2005
42
Pre and post-treatment histopathological changes in atrophic rhinitis. ( 16761739 )
2005
43
Association of growth performance with atrophic rhinitis and pneumonia detected at slaughter in a conventional pig herd in Hungary. ( 16156124 )
2005
44
The aetiology and management of atrophic rhinitis. ( 16354334 )
2005
45
Atrophic rhinitis in a patient with anhidrotic ectodermal dysplasia. ( 16218520 )
2005
46
Development of a genetically modified nontoxigenic Pasteurella multocida toxin as a candidate for use in vaccines against progressive atrophic rhinitis in pigs. ( 15691045 )
2005
47
Atrophic rhinitis in sheep in Austria. ( 14979445 )
2004
48
Differentiation of Pasteurella multocida isolates from cases of atrophic rhinitis in pigs from Zimbabwe by RAPD and ribotyping. ( 15288934 )
2004
49
An experimental mouse model of progressive atrophic rhinitis of swine. ( 15504591 )
2004
50
Endoscopic dacryocystorhinostomy in cases of dacryocystitis due to atrophic rhinitis. ( 15285859 )
2004

Variations for Atrophic Rhinitis

Expression for Atrophic Rhinitis

Search GEO for disease gene expression data for Atrophic Rhinitis.

Pathways for Atrophic Rhinitis

Pathways related to Atrophic Rhinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.64 CTSA IFI30

GO Terms for Atrophic Rhinitis

Cellular components related to Atrophic Rhinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosomal lumen GO:0043202 8.62 CTSA IFI30

Sources for Atrophic Rhinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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