MCID: ATR003
MIFTS: 32

Atrophic Rhinitis malady

Category: Respiratory diseases

Aliases & Classifications for Atrophic Rhinitis

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Aliases & Descriptions for Atrophic Rhinitis:

Name: Atrophic Rhinitis 11 13
Rhinitis, Atrophic 11 39 68
Rhinitis Sicca 11 68
 
Ozena 11 68
Dry Rhinitis 11
Ozaena 11

Classifications:



External Ids:

Disease Ontology11 DOID:4731
SNOMED-CT62 28111002
MeSH39 D012222

Summaries for Atrophic Rhinitis

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Disease Ontology:11 A rhinitis which involves inflammation of the nose characterised by atrophy of nasal mucosa including the glands, turbinate bones, and the nerve elements supplying the nose that is caused by heredity factors, endocrine imbalance, nutritional deficiency, bacterial infection and autoimmune issues.

MalaCards based summary: Atrophic Rhinitis, also known as rhinitis, atrophic, is related to rhinitis and actinobacillosis, and has symptoms including nasal congestion (finding) and rhinorrhea. An important gene associated with Atrophic Rhinitis is XPNPEP2 (X-Prolyl Aminopeptidase 2), and among its related pathways is MHC class II antigen presentation. Affiliated tissues include bone, testes and thyroid.

Related Diseases for Atrophic Rhinitis

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Diseases related to Atrophic Rhinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1rhinitis11.0
2actinobacillosis11.0
3pneumonia10.4
4ectodermal dysplasia10.1
5pleuropneumonia10.0
6leprosy9.7
7osteoporosis9.7
8nasopharyngitis9.7
9lepromatous leprosy9.7
10brucellosis9.7
11myiasis9.7
12diphtheria9.7
13typhoid fever9.7
14hypothyroidism9.7
15tuberculosis9.7
16vasomotor rhinitis9.7
17thyroiditis9.7
18dacryocystitis9.7
19somatoform disorder7.5CD2AP, CTSA, EXT1, IFI30, RPA1, TTC37

Graphical network of diseases related to Atrophic Rhinitis:



Diseases related to atrophic rhinitis

Symptoms & Phenotypes for Atrophic Rhinitis

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UMLS symptoms related to Atrophic Rhinitis:


nasal congestion (finding), rhinorrhea

Drugs & Therapeutics for Atrophic Rhinitis

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Drugs for Atrophic Rhinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineapprovedPhase 1, Phase 277651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2Neurotransmitter AgentsPhase 1, Phase 217734
3onabotulinumtoxinAPhase 1, Phase 2626
4Peripheral Nervous System AgentsPhase 1, Phase 222776
5Neuromuscular AgentsPhase 1, Phase 21129
6Cholinergic AgentsPhase 1, Phase 23846
7Botulinum ToxinsPhase 1, Phase 2669
8Botulinum Toxins, Type APhase 1, Phase 2630
9abobotulinumtoxinAPhase 1, Phase 2626
10incobotulinumtoxinAPhase 1, Phase 2635

Interventional clinical trials:

idNameStatusNCT IDPhase
1Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome SyndromeTerminatedNCT00732680Phase 1, Phase 2
2Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal PolypsRecruitingNCT02855931
3Gore Tex Implants in the Treatment of Atrophic RhinitisSuspendedNCT00832403
4Topical Antibiotic Use In Chronic Rhinosinusitis A Double-Blinded, Randomized, Placebo Controlled StudyWithdrawnNCT00669799

Search NIH Clinical Center for Atrophic Rhinitis


Cochrane evidence based reviews: rhinitis, atrophic

Genetic Tests for Atrophic Rhinitis

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Anatomical Context for Atrophic Rhinitis

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MalaCards organs/tissues related to Atrophic Rhinitis:

36
Bone, Testes, Thyroid, Liver, Colon

Publications for Atrophic Rhinitis

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Articles related to Atrophic Rhinitis:

(show top 50)    (show all 373)
idTitleAuthorsYear
1
Cases and Specimens illustrating Work on Atrophic Rhinitis (OzA (20904129)
na) and Tube
2
Four Cases of Atrophic Rhinitis with OzA (20904898)
na undergoin
3
A Method of treating Atrophic Rhinitis with OzA (20904922)
na based on
4
Empty nose syndrome and atrophic rhinitis. (27613452)
2016
5
Atrophic rhinitis caused by Cedecea davisae with accompanying mucocele. (26211869)
2015
6
Surfactant protein a expression in chronic rhinosinusitis and atrophic rhinitis. (25992168)
2015
7
Immunologic study and optimization of Salmonella delivery strains expressing adhesin and toxin antigens for protection against progressive atrophic rhinitis in a murine model. (25355999)
2014
8
Atrophic rhinitis presenting with ethmoidal mucocele: a case report. (25121010)
2014
9
New regenerative approach to atrophic rhinitis using autologous lipoaspirate transfer and platelet-rich plasma in five patients: Our Experience. (24938860)
2014
10
Complete Genome Sequence of Bordetella bronchiseptica S798, an Isolate from a Pig with Atrophic Rhinitis. (24831150)
2014
11
Generation of an attenuated Salmonella-delivery strains expressing adhesin and toxin antigens for progressive atrophic rhinitis, and evaluation of its immune responses in a murine model. (25045826)
2014
12
Acute Exacerbation of Chronic Rhinosinusitis (AECRS) with Orbital Complications in an Atrophic Rhinitis Patient: A Mere Co-incidence? (24551696)
2013
13
Atrophic rhinitis. (23484896)
2013
14
Chronic rhinosinusitis in ex-lepromatous leprosy patients with atrophic rhinitis. (23398842)
2013
15
Swine atrophic rhinitis caused by pasteurella multocida toxin and bordetella dermonecrotic toxin. (22411430)
2012
16
Chemosensory function assessed with psychophysical testing and event-related potentials in patients with atrophic rhinitis. (21717190)
2012
17
Primary atrophic rhinitis: a clinical profile, microbiological and radiological study. (23762613)
2012
18
Rhinoplasty in atrophic rhinitis. (23025225)
2012
19
Interventions for atrophic rhinitis. (22336840)
2012
20
A new technique for nasal stent fabrication for atrophic rhinitis: a clinical report. (21585589)
2011
21
Rhinitis sicca, dry nose and atrophic rhinitis: a review of the literature. (20878413)
2011
22
Anhidrotic ectodermal dysplasia presenting as atrophic rhinitis. (22666945)
2011
23
Use of computer snout morphometry in atrophic rhinitis monitoring. (21498219)
2011
24
A report on a rare case of Klebsiella ozaenae causing atrophic rhinitis in the UK. (22669526)
2011
25
Study of histopathological changes in primary atrophic rhinitis. (23724252)
2011
26
Primary atrophic rhinitis. (20869578)
2010
27
Efficacy of a novel Pasteurella multocida vaccine against progressive atrophic rhinitis of swine. (19428902)
2009
28
Hypohidrotic ectodermal dysplasia with atrophic rhinitis and nasal myiasis. (19616858)
2009
29
Microbiological study of role of fungi in primary atrophic rhinitis. (18926001)
2009
30
Prosthetic management of atrophic rhinitis. (23120587)
2008
31
Chitosan microspheres containing Bordetella bronchiseptica antigens as novel vaccine against atrophic rhinitis in pigs. (18600065)
2008
32
Novel treatment of atrophic rhinitis: early results. (18317788)
2008
33
Atrophic rhinitis vaccine composition triggers different serological profiles that do not correlate with protection. (18401954)
2008
34
Atrophic rhinitis: a CFD study of air conditioning in the nasal cavity. (17569762)
2007
35
On the risk of carcinomatous change in atrophic rhinitis. (17156518)
2007
36
Rhinoplasty and young's operation in atrophic rhinitis. (23120345)
2006
37
Immunogenicity and efficacy of three recombinant subunit Pasteurella multocida toxin vaccines against progressive atrophic rhinitis in pigs. (16122849)
2006
38
Interesting observations on Primary Atrophic Rhinitis. (23120308)
2006
39
Light and electron microscopic study of primary atrophic rhinitis mucosa. (17063751)
2006
40
Radiology quiz case 4: primary atrophic rhinitis, or ozena. (16103316)
2005
41
The aetiology and management of atrophic rhinitis. (16354334)
2005
42
Association of growth performance with atrophic rhinitis and pneumonia detected at slaughter in a conventional pig herd in Hungary. (16156124)
2005
43
Pre-cancerous changes in the nasal mucosa of atrophic rhinitis: A preliminary report. (23120119)
2005
44
Atrophic rhinitis in a patient with anhidrotic ectodermal dysplasia. (16218520)
2005
45
Development of a genetically modified nontoxigenic Pasteurella multocida toxin as a candidate for use in vaccines against progressive atrophic rhinitis in pigs. (15691045)
2005
46
Pre and post-treatment histopathological changes in atrophic rhinitis. (16761739)
2005
47
Endoscopic dacryocystorhinostomy in cases of dacryocystitis due to atrophic rhinitis. (15285859)
2004
48
Differentiation of Pasteurella multocida isolates from cases of atrophic rhinitis in pigs from Zimbabwe by RAPD and ribotyping. (15288934)
2004
49
Anhidrotic ectodermal dysplasia presenting as atrophic rhinitis. (15318965)
2004
50
An experimental mouse model of progressive atrophic rhinitis of swine. (15504591)
2004

Variations for Atrophic Rhinitis

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Expression for genes affiliated with Atrophic Rhinitis

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Search GEO for disease gene expression data for Atrophic Rhinitis.

Pathways for genes affiliated with Atrophic Rhinitis

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Pathways related to Atrophic Rhinitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CTSA, IFI30

GO Terms for genes affiliated with Atrophic Rhinitis

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Cellular components related to Atrophic Rhinitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lysosomal lumenGO:00432029.5CTSA, IFI30

Sources for Atrophic Rhinitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet