MCID: ATR008
MIFTS: 25

Atrophy of Prostate malady

Categories: Reproductive diseases

Aliases & Classifications for Atrophy of Prostate

Aliases & Descriptions for Atrophy of Prostate:

Name: Atrophy of Prostate 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:2301
ICD9CM 35 602.2
SNOMED-CT 64 29524003
ICD10 33 N42.2
UMLS 69 C0156296

Summaries for Atrophy of Prostate

MalaCards based summary : Atrophy of Prostate is related to uterine disease and rhinitis. An important gene associated with Atrophy of Prostate is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Pathways in cancer and NRF2 pathway. The drugs Finasteride and Methyltestosterone have been mentioned in the context of this disorder. Affiliated tissues include prostate.

Related Diseases for Atrophy of Prostate

Graphical network of the top 20 diseases related to Atrophy of Prostate:



Diseases related to Atrophy of Prostate

Symptoms & Phenotypes for Atrophy of Prostate

Drugs & Therapeutics for Atrophy of Prostate

Drugs for Atrophy of Prostate (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Finasteride Approved Phase 2 98319-26-7 57363
2
Methyltestosterone Approved Phase 2 58-18-4 6010
3
Testosterone Approved, Investigational Phase 2 58-22-0 6013
4
Anastrozole Approved, Investigational Phase 2 120511-73-1 2187
5 5-alpha Reductase Inhibitors Phase 2
6 Anabolic Agents Phase 2
7 Androgens Phase 2
8 Antineoplastic Agents, Hormonal Phase 2
9 Hormone Antagonists Phase 2
10 Hormones Phase 2
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
12 Steroid Synthesis Inhibitors Phase 2
13 Testosterone 17 beta-cypionate Phase 2
14
Testosterone enanthate Phase 2 315-37-7 9416
15 Testosterone undecanoate Phase 2
16 Aromatase Inhibitors Phase 2
17 Bone Density Conservation Agents Phase 2
18 Calcium, Dietary Phase 2
19 Estrogen Antagonists Phase 2
20 Estrogens Phase 2
21 Micronutrients Phase 2
22 Trace Elements Phase 2
23 vitamin d Phase 2
24 Vitamins Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase
1 5-Alpha Reductase and Anabolic Effects of Testosterone Completed NCT00475501 Phase 2
2 Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial. Completed NCT00104572 Phase 2
3 GE-148-002: A Phase 2, Open-label, Single-Center Study to Assess GE-148 (18F) Injection PET Imaging to Detect Localized Prostate Cancer Terminated NCT01176513 Phase 2
4 Transcorporal Versus Standard Artificial Urinary Sphincter Placement Recruiting NCT02591381

Search NIH Clinical Center for Atrophy of Prostate

Genetic Tests for Atrophy of Prostate

Anatomical Context for Atrophy of Prostate

MalaCards organs/tissues related to Atrophy of Prostate:

39
Prostate

Publications for Atrophy of Prostate

Articles related to Atrophy of Prostate:

id Title Authors Year
1
Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation. ( 19245591 )
2009

Variations for Atrophy of Prostate

Expression for Atrophy of Prostate

Search GEO for disease gene expression data for Atrophy of Prostate.

Pathways for Atrophy of Prostate

GO Terms for Atrophy of Prostate

Biological processes related to Atrophy of Prostate according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein complex assembly GO:0006461 9.4 SLC2A1 TP53
2 regulation of insulin secretion GO:0050796 9.37 SLC2A1 SLC2A2
3 carbohydrate transport GO:0008643 9.32 SLC2A1 SLC2A2
4 glucose transport GO:0015758 9.26 SLC2A1 SLC2A2
5 cellular response to glucose starvation GO:0042149 9.16 SLC2A1 TP53
6 glucose transmembrane transport GO:1904659 8.96 SLC2A1 SLC2A2
7 dehydroascorbic acid transport GO:0070837 8.62 SLC2A1 SLC2A2

Molecular functions related to Atrophy of Prostate according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transmembrane transporter activity GO:0022857 9.37 SLC2A1 SLC2A2
2 protein self-association GO:0043621 9.32 SLC2A1 TP53
3 substrate-specific transmembrane transporter activity GO:0022891 9.26 SLC2A1 SLC2A2
4 glucose transmembrane transporter activity GO:0005355 9.16 SLC2A1 SLC2A2
5 D-glucose transmembrane transporter activity GO:0055056 8.96 SLC2A1 SLC2A2
6 dehydroascorbic acid transporter activity GO:0033300 8.62 SLC2A1 SLC2A2

Sources for Atrophy of Prostate

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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