MCID: ATR009
MIFTS: 17

Atrophy of Testis malady

Categories: Reproductive diseases

Aliases & Classifications for Atrophy of Testis

Aliases & Descriptions for Atrophy of Testis:

Name: Atrophy of Testis 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:11994
ICD10 33 N50.0
ICD9CM 35 608.3
NCIt 47 C123259
UMLS 69 C0156312

Summaries for Atrophy of Testis

MalaCards based summary : Atrophy of Testis is related to female reproductive organ cancer. An important gene associated with Atrophy of Testis is DBT (Dihydrolipoamide Branched Chain Transacylase E2), and among its related pathways/superpathways is Striated Muscle Contraction. The drug Menthol has been mentioned in the context of this disorder. Affiliated tissues include testis.

Related Diseases for Atrophy of Testis

Diseases related to Atrophy of Testis via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 female reproductive organ cancer 9.1 CSN1S1 DBT GNRH1 NQO1 TNNI1 TNNI2

Symptoms & Phenotypes for Atrophy of Testis

Drugs & Therapeutics for Atrophy of Testis

Drugs for Atrophy of Testis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved 2216-51-5 16666

Interventional clinical trials:


id Name Status NCT ID Phase
1 Laparoscopic Inguinal Hernia Repair in Infancy and Childhood Unknown status NCT02239185 Phase 3
2 Testicular Injection of Autologous Stem Cells for Treatment of Patients With Azoospermia Unknown status NCT02041910 Phase 1, Phase 2
3 A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children Recruiting NCT02960529 Phase 2
4 Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years Unknown status NCT00716768
5 A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC) Unknown status NCT01883115
6 Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy Completed NCT02092311
7 A Prospective Study Comparing Single and Multiport Laparoscopic Inguinal Hernia Repair Completed NCT01660048
8 SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery Recruiting NCT02415543
9 One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO) Not yet recruiting NCT02936024

Search NIH Clinical Center for Atrophy of Testis

Genetic Tests for Atrophy of Testis

Anatomical Context for Atrophy of Testis

MalaCards organs/tissues related to Atrophy of Testis:

39
Testis

Publications for Atrophy of Testis

Variations for Atrophy of Testis

Expression for Atrophy of Testis

Search GEO for disease gene expression data for Atrophy of Testis.

Pathways for Atrophy of Testis

Pathways related to Atrophy of Testis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.48 TNNI1 TNNI2

GO Terms for Atrophy of Testis

Cellular components related to Atrophy of Testis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 troponin complex GO:0005861 8.62 TNNI1 TNNI2

Biological processes related to Atrophy of Testis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.37 GNRH1 NQO1
2 response to organic cyclic compound GO:0014070 9.32 GNRH1 NQO1
3 response to ethanol GO:0045471 9.26 GNRH1 NQO1
4 cardiac muscle contraction GO:0060048 9.16 TNNI1 TNNI2
5 muscle filament sliding GO:0030049 8.96 TNNI1 TNNI2
6 skeletal muscle contraction GO:0003009 8.62 TNNI1 TNNI2

Sources for Atrophy of Testis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....