MCID: ATR009
MIFTS: 18

Atrophy of Testis

Categories: Reproductive diseases

Aliases & Classifications for Atrophy of Testis

MalaCards integrated aliases for Atrophy of Testis:

Name: Atrophy of Testis 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:11994
ICD10 32 N50.0
ICD9CM 34 608.3
NCIt 46 C123259
UMLS 69 C0156312

Summaries for Atrophy of Testis

MalaCards based summary : Atrophy of Testis is related to pelvic varices. An important gene associated with Atrophy of Testis is DBT (Dihydrolipoamide Branched Chain Transacylase E2), and among its related pathways/superpathways is Striated Muscle Contraction. The drugs Menthol and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include testis.

Related Diseases for Atrophy of Testis

Diseases related to Atrophy of Testis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pelvic varices 9.4 CSN1S1 GNRH1

Symptoms & Phenotypes for Atrophy of Testis

Drugs & Therapeutics for Atrophy of Testis

Drugs for Atrophy of Testis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved 2216-51-5 16666
2 Analgesics
3 Anti-Inflammatory Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Laparoscopic Inguinal Hernia Repair in Infancy and Childhood Unknown status NCT02239185 Phase 3
2 A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children Recruiting NCT02960529 Phase 2
3 Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years Unknown status NCT00716768
4 A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC) Unknown status NCT01883115
5 Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy Completed NCT02092311
6 A Prospective Study Comparing Single and Multiport Laparoscopic Inguinal Hernia Repair Completed NCT01660048
7 One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO) Recruiting NCT02936024
8 SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery Recruiting NCT02415543
9 Comparison of Recurrence Rate of 2 Herniotomy Techniques in Children Older Than 2 Years Enrolling by invitation NCT03392636
10 Varicocele Treatement by Endovasculer Embolization Not yet recruiting NCT03341897

Search NIH Clinical Center for Atrophy of Testis

Genetic Tests for Atrophy of Testis

Anatomical Context for Atrophy of Testis

MalaCards organs/tissues related to Atrophy of Testis:

38
Testis

Publications for Atrophy of Testis

Variations for Atrophy of Testis

Expression for Atrophy of Testis

Search GEO for disease gene expression data for Atrophy of Testis.

Pathways for Atrophy of Testis

Pathways related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.48 TNNI1 TNNI2

GO Terms for Atrophy of Testis

Cellular components related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 troponin complex GO:0005861 8.62 TNNI1 TNNI2

Biological processes related to Atrophy of Testis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.37 GNRH1 NQO1
2 response to organic cyclic compound GO:0014070 9.32 GNRH1 NQO1
3 response to ethanol GO:0045471 9.26 GNRH1 NQO1
4 cardiac muscle contraction GO:0060048 9.16 TNNI1 TNNI2
5 muscle filament sliding GO:0030049 8.96 TNNI1 TNNI2
6 skeletal muscle contraction GO:0003009 8.62 TNNI1 TNNI2

Sources for Atrophy of Testis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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