ADHD
MCID: ATT002
MIFTS: 54

Attention Deficit Hyperactivity Disorder (ADHD) malady

Summaries for Attention Deficit Hyperactivity Disorder

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8Disease Ontology, 33MedlinePlus, 3CDC, 43NINDS, 63Wikipedia, 46OMIM, 32MalaCards
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NINDS:43 Attention deficit-hyperactivity disorder (ADHD) is a neurobehavioral disorder that affects 3-5 percent of all American children. It interferes with a person's ability to stay on a task and to exercise age-appropriate inhibition (cognitive alone or both cognitive and behavioral). Some of the warning signs of ADHD include failure to listen to instructions, inability to organize oneself and school work, fidgeting with hands and feet, talking too much, leaving projects, chores and homework unfinished, and having trouble paying attention to and responding to details. There are several types of ADHD: a predominantly inattentive subtype, a predominantly hyperactive-impulsive subtype, and a combined subtype. ADHD is usually diagnosed in childhood, although the condition can continue into the adult years.

MalaCards: Attention Deficit Hyperactivity Disorder, also known as attention deficit disorder, is related to conduct disorder and autism spectrum disorder. An important gene associated with Attention Deficit Hyperactivity Disorder is DRD4 (dopamine receptor D4). The drugs amphetamine and clonidine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Disease Ontology:8 A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone" and symptoms starting before seven years of age.

MedlinePlus:33 Is it hard for your child to sit still? does your child act without thinking first? does your child start but not finish things? if so, your child may have attention deficit hyperactivity disorder (adhd). nearly everyone shows some of these behaviors at times, but adhd lasts more than 6 months and causes problems in school, at home and in social situations. adhd is more common in boys than girls. it affects 3-5 percent of all american children. the main features of adhd are inattention hyperactivity impulsivity no one knows exactly what causes adhd. it sometimes runs in families, so genetics may be a factor. there may also be environmental factors. a complete evaluation by a trained professional is the only way to know for sure if your child has adhd. treatment may include medicine to control symptoms, therapy, or both. structure at home and at school is important. parent training may also help. nih: national institute of mental health

CDC:3 People with ADHD may have trouble paying attention, controlling impulsive behaviors (may act without thinking about what the result will be), or be overly active. Although ADHD can't be cured, it can be successfully managed and some symptoms may improve as the child ages.

Wikipedia:63 Attention deficit hyperactivity disorder (ADHD, similar to hyperkinetic disorder in the ICD-10) is a... more...

Description from OMIM:46 143465

Aliases & Classifications for Attention Deficit Hyperactivity Disorder

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32MalaCards, 8Disease Ontology, 9diseasecard, 22GTR, 43NINDS, 46OMIM, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

attention deficit hyperactivity disorder 32 8 10 33 60
attention deficit disorder 8 44 60
attention deficit-hyperactivity disorder, susceptibility to 9 22
attention deficit-hyperactivity disorder 43 46
adhd 32 43
attention-deficit hyperactivity disorder 44
hyperkinesis 8


External Ids:

Disease Ontology8 DOID:1094
MeSH34 D001289
SNOMED-CT56 23148009
NCIt39 C35092

Related Diseases for Attention Deficit Hyperactivity Disorder

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Attention Deficit Hyperactivity Disorder:



Diseases related to attention deficit hyperactivity disorder

Clinical Features for Attention Deficit Hyperactivity Disorder

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46OMIM
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Clinical features from OMIM:

143465

Clinical synopsis from OMIM:

143465

Drugs & Therapeutics for Attention Deficit Hyperactivity Disorder

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Attention Deficit Hyperactivity Disorder

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22GTR
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Genetic tests related to Attention Deficit Hyperactivity Disorder:

id Genetic test Affiliating Genes
1 Attention Deficit-Hyperactivity Disorder22

Anatomical Context for Attention Deficit Hyperactivity Disorder

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32MalaCards
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MalaCards organs/tissues related to Attention Deficit Hyperactivity Disorder:

32
Brain, Testes, Eye, Heart, Thyroid, Cortex, Cingulate cortex, Prefrontal cortex, Skin, Amygdala

Animal Models for Attention Deficit Hyperactivity Disorder or affiliated genes

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Publications for Attention Deficit Hyperactivity Disorder

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50PubMed
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Articles related to Attention Deficit Hyperactivity Disorder:

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idTitleAuthorsYear
1
Cerebellar morphology and the effects of stimulant medications in youths with attention deficit-hyperactivity disorder. (24077064)
2014
2
AZD3480, a Novel Nicotinic Receptor Agonist, for the Treatment of Attention-Deficit/Hyperactivity Disorder in Adults. (23856296)
2014
3
Attention Deficit Hyperactivity Disorder and N-methyl-D-aspartate (NMDA) Dysregulation. (24410567)
2014
4
Need for Care and Life Satisfaction in Adult Substance Use Disorder Patients With and Without Attention Deficit Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD). (24410895)
2014
5
Evaluation of attention-deficit hyperactivity disorder risk factors. (24319465)
2013
6
Attention-deficit/hyperactivity disorder without comorbidity is associated with distinct atypical patterns of cerebral microstructural development. (23907808)
2013
7
Baseline characteristics of European and non-European adult patients with attention deficit hyperactivity disorder participating in a placebo-controlled, randomized treatment study with atomoxetine. (23648011)
2013
8
Complex prospective memory in adults with attention deficit hyperactivity disorder. (23484020)
2013
9
The ex-Gaussian distribution of reaction times in adolescents with attention-deficit/hyperactivity disorder. (24021389)
2013
10
Lipid peroxidation markers in adult attention deficit hyperactivity disorder: new findings for oxidative stress. (23680468)
2013
11
The association of attention deficit hyperactivity disorder with socioeconomic disadvantage: alternative explanations and evidence. (24274762)
2013
12
Methylphenidate and continuous spike and wave during sleep in a child with attention deficit hyperactivity disorder. (23827428)
2013
13
The relationship between autism spectrum disorders and attention-deficit/hyperactivity disorder: an overview. (23751293)
2013
14
Attention deficit hyperactivity disorder and dual disorders. Educational needs for an underdiagnosed condition. (23846135)
2013
15
Examining the relationships between attention deficit/hyperactivity disorder and developmental coordination disorder symptoms, and writing performance in Japanese second grade students. (23810930)
2013
16
Lamotrigine for attention deficit-hyperactivity disorder comorbid with mood disorders: a case series. (23784736)
2013
17
The relationship of Internet addiction severity with Attention Deficit Hyperactivity Disorder symptoms in Turkish University students; impact of personality traits, depression and anxiety. (24374171)
2013
18
Adolescence methylphenidate treatment in a rodent model of attention deficit/hyperactivity disorder: dopamine transporter function and cellular distribution in adulthood. (23623751)
2013
19
Regional differences in cerebral perfusion associated with the alpha-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorder. (20731965)
2010
20
Further evidence for the association between attention deficit/hyperactivity disorder and the serotonin receptor 1B gene. (19756364)
2009
21
A psycho-genetic study of associations between the symptoms of binge eating disorder and those of attention deficit (hyperactivity) disorder. (19041097)
2009
22
A case-control association study of the polymorphism at the promoter region of the DRD4 gene in Korean boys with attention deficit-hyperactivity disorder: evidence of association with the -521 C/T SNP. (17850946)
2008
23
Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE) program. (18163388)
2008
24
No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder. (18452186)
2008
25
Genotype and neuropsychological response inhibition as resilience promoters for attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder under conditions of psychosocial adversity. (17705902)
2007
26
Ziprasidone for maladaptive behavior and attention-deficit/hyperactivity disorder symptoms in autistic disorder. (17489724)
2007
27
Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): an update. (17171657)
2007
28
Developmental coordination disorder in children with attention-deficit-hyperactivity disorder and physical therapy intervention. (18039239)
2007
29
DAT1 3'-UTR 9R allele: preferential transmission in Indian children with attention deficit hyperactivity disorder. (17440935)
2007
30
Response variability in Attention-Deficit/Hyperactivity Disorder: a neuronal and glial energetics hypothesis. (16925830)
2006
31
Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. (16585476)
2006
32
Comparison of psychosocial correlates in primary school age children with attention deficit/ hyperactivity disorder- combined type, with and without dysthymic disorder. (16755402)
2006
33
Attention deficit hyperactivity disorder, combined type, dysthymic disorder and anxiety disorders: differential patterns of neurodevelopmental deficits. (16876876)
2006
34
Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder. (15059031)
2004
35
Association studies of G352A polymorphism of dopamine transporter gene in Han Chinese attention deficit hyperactivity disorder patients]. (15605097)
2004
36
Mutational analysis of the nicotinic acetylcholine receptor alpha 4 subunit gene in attention deficit/hyperactivity disorder: evidence for association of an intronic polymorphism with attention problems. (12556914)
2003
37
Association between tryptophan hydroxylase gene polymorphisms and attention deficit hyperactivity disorder with or without learning disorder]. (14720417)
2003
38
Association analysis between attention-deficit hyperactivity disorder and Val158Met polymorphism of catechol-O-methyltransferase gene]. (12903043)
2003
39
Relation between childhood disruptive behavior disorders and substance use and dependence symptoms in young adulthood: individuals with symptoms of attention-deficit/hyperactivity disorder and conduct disorder are uniquely at risk. (12814279)
2003
40
Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA). (12140786)
2002
41
Genetic linkage of attention-deficit/hyperactivity disorder on chromosome 16p13, in a region implicated in autism. (12187510)
2002
42
Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene. (11857576)
2002
43
Timing and force control in boys with attention deficit hyperactivity disorder: subtype differences and the effect of comorbid developmental coordination disorder. (12620726)
2002
44
The dopamine transporter: relevance to attention deficit hyperactivity disorder (ADHD). (11864718)
2002
45
Preferential transmission of interleukin-1 receptor antagonist alleles in attention deficit hyperactivity disorder. (11803448)
2002
46
Comparative study of the behavioral and neuropsychologic characteristics of tic disorder with or without attention-deficit hyperactivity disorder (ADHD). (11669344)
2001
47
No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample. (10898900)
2000
48
Problem of item overlap between the psychopathy screening device and attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder rating scales. (11147115)
2000
49
No evidence of linkage or linkage disequilibrium between DAT1 and attention deficit hyperactivity disorder in a large sample. (10551548)
1999
50
Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder. (9118321)
1996

Genetic Variations for Attention Deficit Hyperactivity Disorder

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Expression for genes affiliated with Attention Deficit Hyperactivity Disorder

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Attention Deficit Hyperactivity Disorder

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Pathways for genes affiliated with Attention Deficit Hyperactivity Disorder

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Compounds for genes affiliated with Attention Deficit Hyperactivity Disorder

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GO Terms for genes affiliated with Attention Deficit Hyperactivity Disorder

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Products for genes affiliated with Attention Deficit Hyperactivity Disorder

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Sources for Attention Deficit Hyperactivity Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet