ADHD
MCID: ATT002
MIFTS: 54

Attention Deficit Hyperactivity Disorder (ADHD) malady

Summaries for Attention Deficit Hyperactivity Disorder

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8Disease Ontology, 33MedlinePlus, 3CDC, 43NINDS, 63Wikipedia, 46OMIM, 32MalaCards
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NINDS:43 Attention deficit-hyperactivity disorder (ADHD) is a neurobehavioral disorder that affects 3-5 percent of all American children. It interferes with a person's ability to stay on a task and to exercise age-appropriate inhibition (cognitive alone or both cognitive and behavioral). Some of the warning signs of ADHD include failure to listen to instructions, inability to organize oneself and school work, fidgeting with hands and feet, talking too much, leaving projects, chores and homework unfinished, and having trouble paying attention to and responding to details. There are several types of ADHD: a predominantly inattentive subtype, a predominantly hyperactive-impulsive subtype, and a combined subtype. ADHD is usually diagnosed in childhood, although the condition can continue into the adult years.

MalaCards: Attention Deficit Hyperactivity Disorder, also known as attention deficit disorder, is related to conduct disorder and autism spectrum disorder. An important gene associated with Attention Deficit Hyperactivity Disorder is DRD4 (dopamine receptor D4). The drugs amphetamine and clonidine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Disease Ontology:8 A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone" and symptoms starting before seven years of age.

MedlinePlus:33 Is it hard for your child to sit still? does your child act without thinking first? does your child start but not finish things? if so, your child may have attention deficit hyperactivity disorder (adhd). nearly everyone shows some of these behaviors at times, but adhd lasts more than 6 months and causes problems in school, at home and in social situations. adhd is more common in boys than girls. it affects 3-5 percent of all american children. the main features of adhd are inattention hyperactivity impulsivity no one knows exactly what causes adhd. it sometimes runs in families, so genetics may be a factor. there may also be environmental factors. a complete evaluation by a trained professional is the only way to know for sure if your child has adhd. treatment may include medicine to control symptoms, therapy, or both. structure at home and at school is important. parent training may also help. nih: national institute of mental health

CDC:3 People with ADHD may have trouble paying attention, controlling impulsive behaviors (may act without thinking about what the result will be), or be overly active. Although ADHD can't be cured, it can be successfully managed and some symptoms may improve as the child ages.

Wikipedia:63 Attention deficit hyperactivity disorder (ADHD, similar to hyperkinetic disorder in the ICD-10) is a... more...

Description from OMIM:46 143465

Aliases & Classifications for Attention Deficit Hyperactivity Disorder

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32MalaCards, 8Disease Ontology, 9diseasecard, 22GTR, 43NINDS, 46OMIM, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

attention deficit hyperactivity disorder 32 8 10 33 60
attention deficit disorder 8 44 60
attention deficit-hyperactivity disorder, susceptibility to 9 22
attention deficit-hyperactivity disorder 43 46
adhd 32 43
attention-deficit hyperactivity disorder 44
hyperkinesis 8


External Ids:

Disease Ontology8 DOID:1094
MeSH34 D001289
SNOMED-CT56 23148009
NCIt39 C35092

Related Diseases for Attention Deficit Hyperactivity Disorder

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Attention Deficit Hyperactivity Disorder:



Diseases related to attention deficit hyperactivity disorder

Clinical Features for Attention Deficit Hyperactivity Disorder

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46OMIM
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Clinical features from OMIM:

143465

Clinical synopsis from OMIM:

143465

Drugs & Therapeutics for Attention Deficit Hyperactivity Disorder

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Attention Deficit Hyperactivity Disorder

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22GTR
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Genetic tests related to Attention Deficit Hyperactivity Disorder:

id Genetic test Affiliating Genes
1 Attention Deficit-Hyperactivity Disorder22

Anatomical Context for Attention Deficit Hyperactivity Disorder

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32MalaCards
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MalaCards organs/tissues related to Attention Deficit Hyperactivity Disorder:

32
Brain, Testes, Eye, Heart, Thyroid, Cortex, Cingulate cortex, Prefrontal cortex, Skin, Amygdala

Animal Models for Attention Deficit Hyperactivity Disorder or affiliated genes

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Publications for Attention Deficit Hyperactivity Disorder

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50PubMed
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Articles related to Attention Deficit Hyperactivity Disorder:

(show top 50)    (show all 1144)
idTitleAuthorsYear
1
Response time of visual matching task and heart rate in children with Attention Deficit Hyperactivity Disorder (ADHD). (24211988)
2014
2
Subthreshold attention-deficit/hyperactivity disorder is associated with functional impairments across domains: a comprehensive analysis in a large-scale community study. (24318039)
2013
3
Methylphenidate treatment of attention deficit hyperactivity disorder in young people with learning disability and difficult-to-treat epilepsy: Evidence of clinical benefit. (24304474)
2013
4
Attention Deficit Hyperactivity Disorder. (24214656)
2013
5
Guanfacine extended release: a novel treatment for attention-deficit/hyperactivity disorder in children and adolescents. (24139092)
2013
6
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. (23728934)
2013
7
Anti-Purkinje cell antibody as a biological marker in attention deficit/hyperactivity disorder: a pilot study. (23510584)
2013
8
Effects of Methylphenidate on Cognitive Functions in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: Evidence from a Systematic Review and a Meta-Analysis. (24231201)
2013
9
Brief report: Prevalence of attention deficit/hyperactivity disorder among individuals with an autism spectrum disorder. (23065101)
2013
10
Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010. (24117530)
2013
11
Predictors and consequences of adherence to the treatment of pediatric patients with attention-deficit/hyperactivity disorder in Central Europe and East Asia. (24124351)
2013
12
Health-related quality of life and functional outcomes from a randomized, controlled study of lisdexamfetamine dimesylate in children and adolescents with attention deficit hyperactivity disorder. (23893527)
2013
13
Guanfacine-Induced Lichenoid Drug Eruption in a Child with Autism and Attention Deficit Hyperactivity Disorder. (23869619)
2013
14
Measuring adult Attention Deficit Hyperactivity Disorder using the Quantified Behavior Test Plus. (24294490)
2013
15
Evaluation of a computer-based neuropsychological training in children with attention-deficit hyperactivity disorder (ADHD). (23648609)
2013
16
Haplotype co-segregation with attention deficit-hyperactivity disorder in unrelated German multi-generation families. (24038763)
2013
17
Clinical and acoustic vocal profile in children with attention deficit hyperactivity disorder. (24246332)
2013
18
Association between the self-insertion of nasal and aural foreign bodies and attention-deficit/hyperactivity disorder in children. (23751280)
2013
19
Spatial processing in adults with attention deficit hyperactivity disorder. (23937479)
2013
20
Methylphenidate and venlafaxine attenuate locomotion in spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder, through I+2-adrenoceptor activation. (23751518)
2013
21
Regional brain perfusion before and after treatment with methylphenidate may be associated with the G1287A polymorphism of the norepinephrine transporter gene in children with attention-deficit/hyperactivity disorder. (22405810)
2012
22
Executive function in children with pervasive developmental disorder and attention-deficit/hyperactivity disorder assessed by the Keio version of the Wisconsin card sorting test. (21917389)
2012
23
Differentiating children with attention-deficit/hyperactivity disorder, conduct disorder, learning disabilities and autistic spectrum disorders by means of their motor behavior characteristics. (22093665)
2012
24
Attentional performance in children and adolescents with tic disorder and co-occurring attention-deficit/hyperactivity disorder: new insights from a 2 A9 2 factorial design study. (21331638)
2011
25
Attention-deficit hyperactivity disorder and intellectual disability: a study of association with brain-derived neurotrophic factor gene polymorphisms. (20943059)
2010
26
Atomoxetine for attention deficit hyperactivity disorder in mental retardation. (20933178)
2010
27
A haplotype of the norepinephrine transporter (Net) gene Slc6a2 is associated with clinical response to atomoxetine in attention-deficit hyperactivity disorder (ADHD). (19387424)
2009
28
Attention Deficit Hyperactivity Disorder comorbid oppositional defiant disorder and its predominately inattentive type: evidence for an association with COMT but not MAOA in a Chinese sample. (19228412)
2009
29
Comorbidity of alcohol and substance dependence with attention-deficit/hyperactivity disorder (ADHD). (18326548)
2008
30
Genome-wide association scan of attention deficit hyperactivity disorder. (18980221)
2008
31
Somatosensory evoked potentials in attention deficit/hyperactivity disorder and tic disorder. (17466583)
2007
32
Clinical and psychoeducational profile of children with specific learning disability and co-occurring attention-deficit hyperactivity disorder. (18174633)
2007
33
Possible association of the alpha-2A adrenergic receptor gene (ADRA2A) with symptoms of attention-deficit/hyperactivity disorder. (16389583)
2006
34
No association between VNTR polymorphisms of dopamine transporter gene and attention deficit hyperactivity disorder in Chinese children. (16402340)
2006
35
Controlled study of switching from attention-deficit/hyperactivity disorder to a prepubertal and early adolescent bipolar I disorder phenotype during 6-year prospective follow-up: rate, risk, and predictors. (17064428)
2006
36
Atomoxetine: a new treatment for Attention Deficit/Hyperactivity Disorder (ADHD) in children and adolescents]. (16142049)
2005
37
Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder. (16172615)
2005
38
Idiopathic chronic sleep onset insomnia in attention-deficit/hyperactivity disorder: a circadian rhythm sleep disorder. (16076654)
2005
39
Family-based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: no evidence for association in UK and Taiwanese samples. (16082690)
2005
40
Association of the dopamine D5 receptor with attention deficit hyperactivity disorder (ADHD) and scores on a continuous performance test (TOVA). (15108184)
2004
41
The norepinephrine transporter gene and attention-deficit hyperactivity disorder. (11920844)
2002
42
Antecedents of opioid dependence and personality disorder: attention-deficit/hyperactivity disorder and conduct disorder. (11315518)
2001
43
Disinhibitory psychopathology in male adolescents: discriminating conduct disorder from attention-deficit/hyperactivity disorder through concurrent assessment of multiple autonomic states. (11727950)
2001
44
Failure to replicate an association between the catechol-O-methyltransferase polymorphism and attention deficit hyperactivity disorder in a second, independently recruited Israeli cohort. (11121197)
2000
45
Prevalence of attention-deficit/hyperactivity disorder and conduct disorder among substance abusers. (10830144)
2000
46
Long-term methylphenidate therapy in children with comorbid attention-deficit hyperactivity disorder and chronic multiple tic disorder. (10197827)
1999
47
Aggressive behavior in patients with attention-deficit/hyperactivity disorder, conduct disorder, and pervasive developmental disorders. (10418807)
1999
48
Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder. (9774776)
1998
49
Serotonin, aggression, and parental psychopathology in children with attention-deficit hyperactivity disorder. (9334552)
1997
50
School observations of children with attention-deficit hyperactivity disorder and comorbid tic disorder: effects of methylphenidate treatment. (7560119)
1995

Genetic Variations for Attention Deficit Hyperactivity Disorder

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Expression for genes affiliated with Attention Deficit Hyperactivity Disorder

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Attention Deficit Hyperactivity Disorder

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Pathways for genes affiliated with Attention Deficit Hyperactivity Disorder

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Compounds for genes affiliated with Attention Deficit Hyperactivity Disorder

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GO Terms for genes affiliated with Attention Deficit Hyperactivity Disorder

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Products for genes affiliated with Attention Deficit Hyperactivity Disorder

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Sources for Attention Deficit Hyperactivity Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet