ADHD
MCID: ATT002
MIFTS: 54

Attention Deficit Hyperactivity Disorder (ADHD) malady

Fetal diseases category
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Summaries for Attention Deficit Hyperactivity Disorder

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Sources:
9Disease Ontology, 35MedlinePlus, 4CDC, 45NINDS, 66Wikipedia, 48OMIM, 34MalaCards
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NINDS:45 Attention deficit-hyperactivity disorder (ADHD) is a neurobehavioral disorder that affects 3-5 percent of all American children. It interferes with a person's ability to stay on a task and to exercise age-appropriate inhibition (cognitive alone or both cognitive and behavioral). Some of the warning signs of ADHD include failure to listen to instructions, inability to organize oneself and school work, fidgeting with hands and feet, talking too much, leaving projects, chores and homework unfinished, and having trouble paying attention to and responding to details. There are several types of ADHD: a predominantly inattentive subtype, a predominantly hyperactive-impulsive subtype, and a combined subtype. ADHD is usually diagnosed in childhood, although the condition can continue into the adult years.

MalaCards: Attention Deficit Hyperactivity Disorder, also known as attention deficit disorder, is related to conduct disorder and autism spectrum disorder. An important gene associated with Attention Deficit Hyperactivity Disorder is DRD4 (dopamine receptor D4). The drugs amphetamine and clonidine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Disease Ontology:9 A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone" and symptoms starting before seven years of age.

MedlinePlus:35 Is it hard for your child to sit still? does your child act without thinking first? does your child start but not finish things? if so, your child may have attention deficit hyperactivity disorder (adhd). nearly everyone shows some of these behaviors at times, but adhd lasts more than 6 months and causes problems in school, at home and in social situations. adhd is more common in boys than girls. it affects 3-5 percent of all american children. the main features of adhd are inattention hyperactivity impulsivity no one knows exactly what causes adhd. it sometimes runs in families, so genetics may be a factor. there may also be environmental factors. a complete evaluation by a trained professional is the only way to know for sure if your child has adhd. treatment may include medicine to control symptoms, therapy, or both. structure at home and at school is important. parent training may also help. nih: national institute of mental health

CDC:4 People with ADHD may have trouble paying attention, controlling impulsive behaviors (may act without thinking about what the result will be), or be overly active. Although ADHD can't be cured, it can be successfully managed and some symptoms may improve as the child ages.

Wikipedia:66 Attention deficit hyperactivity disorder (ADHD, similar to hyperkinetic disorder in the ICD-10) is a... more...

Description from OMIM:48 143465

Aliases & Classifications for Attention Deficit Hyperactivity Disorder

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Sources:
34MalaCards, 9Disease Ontology, 11DISEASES, 35MedlinePlus, 63UMLS, 45NINDS, 46Novoseek, 10diseasecard, 23GTR, 48OMIM, 36MeSH, 59SNOMED-CT, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


Aliases & Descriptions:

attention deficit hyperactivity disorder 34 9 11 35 63
attention deficit disorder 9 46 63
attention deficit-hyperactivity disorder, susceptibility to 10 23
attention deficit-hyperactivity disorder 45 48
adhd 34 45
attention-deficit hyperactivity disorder 46
hyperkinesis 9


External Ids:

Disease Ontology9 DOID:1094
MeSH36 D001289
SNOMED-CT59 23148009
NCIt41 C35092

Related Diseases for Attention Deficit Hyperactivity Disorder

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Attention Deficit Hyperactivity Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 147)
idRelated DiseaseScoreTop Affiliating Genes
1conduct disorder11.1
2autism spectrum disorder11.0
3tic disorder11.0
4oppositional defiant disorder10.9
5pervasive developmental disorder10.9
6blindness10.9
7developmental coordination disorder10.9
8schizophrenia10.9
9bipolar disorder10.8
10learning disability10.8
11obesity10.8
12personality disorder10.8
13autistic disorder10.7
14hypertension10.7
15dyslexia10.7
16cerebritis10.7
17restless legs syndrome10.7
18dysthymic disorder10.7
19reading disorder10.7
20obsessive-compulsive disorder10.6
21borderline personality disorder10.6
22anxiety disorder10.6
23fetal alcohol spectrum disorder10.6
24childhood-onset schizophrenia10.6
25mental retardation10.6
26bipolar i disorder10.6
27eating disorder10.6
28substance dependence10.6
29major depressive disorder10.5
30chronic tic disorder10.5
31cocaine dependence10.5
32cocaine abuse10.5
33velocardiofacial syndrome10.5
34alcohol dependence10.5
35nicotine dependence10.5
36intellectual disability10.5
37mood disorder10.5
38pervasive developmental disorder not otherwise specified10.5
39neurofibromatosis10.4
40antisocial personality disorder10.4
41neuronitis10.4
42periodic limb movement disorder10.4
43post-traumatic stress disorder10.4
44chronic fatigue syndrome10.4
45coloboma10.4
46asperger syndrome10.4
47bulimia nervosa10.4
48kleptomania10.4
49fragile x syndrome10.4
50sleep disorder10.4

Graphical network of the top 20 diseases related to Attention Deficit Hyperactivity Disorder:



Diseases related to attention deficit hyperactivity disorder

Symptoms for Attention Deficit Hyperactivity Disorder

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Sources:
48OMIM
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Symptoms by clinical synopsis from OMIM:

143465

Clinical features from OMIM:

143465

Drugs & Therapeutics for Attention Deficit Hyperactivity Disorder

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Sources:
43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Genetic Tests for Attention Deficit Hyperactivity Disorder

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23GTR
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Genetic tests related to Attention Deficit Hyperactivity Disorder:

id Genetic test Affiliating Genes
1 Attention Deficit-Hyperactivity Disorder23

Anatomical Context for Attention Deficit Hyperactivity Disorder

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34MalaCards
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MalaCards organs/tissues related to Attention Deficit Hyperactivity Disorder:

34
Brain, Testes, Eye, Thyroid, Heart, Cortex, Prefrontal cortex, Amygdala, Skin, Cingulate cortex

Animal Models for Attention Deficit Hyperactivity Disorder or affiliated genes

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Publications for Attention Deficit Hyperactivity Disorder

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Sources:
53PubMed
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Articles related to Attention Deficit Hyperactivity Disorder:

(show top 50)    (show all 1121)
idTitleAuthorsYear
1
Cerebellar morphology and the effects of stimulant medications in youths with attention deficit-hyperactivity disorder. (24077064)
2014
2
Nicotinic attention-deficit/hyperactivity disorder treatment. (24370349)
2014
3
Association between TPH2 gene polymorphisms and attention deficit hyperactivity disorder in Korean children. (23461725)
2013
4
Objective measurement of weekly physical activity and sensory modulation problems in children with attention deficit hyperactivity disorder. (23927990)
2013
5
Influence of attention-deficit/hyperactivity disorder on binge eating behaviors and psychiatric comorbidity profile of obese women. (24246603)
2013
6
Attention deficit hyperactivity disorder in cocaine-dependent adults: a psychiatric comorbidity analysis. (23952892)
2013
7
Adult attention deficit hyperactivity disorder symptoms and five-factor model traits in a clinical sample: a structural equation modeling approach. (24080671)
2013
8
The role of obsessive-compulsive symptoms in the psychopathological profile of children with chronic tic disorder and attention-deficit hyperactivity disorder. (23639924)
2013
9
Subthreshold attention-deficit/hyperactivity disorder is associated with functional impairments across domains: a comprehensive analysis in a large-scale community study. (24318039)
2013
10
EEG brain mapping and brain connectivity index for subtypes classification of attention deficit hyperactivity disorder children during the eye-opened period. (24111455)
2013
11
Attention-deficit/hyperactivity disorder, physical health, and lifestyle in older adults. (23711084)
2013
12
Early-age clinical and developmental features associated to Substance Use Disorders in Attention-Deficit/Hyperactivity Disorder in Adults. (24411652)
2013
13
The merit of sociological accounts of disorder: The Attention-Deficit Hyperactivity Disorder case. (24287297)
2013
14
Reply to: Attention-Deficit/Hyperactivity Disorder and Solar Irradiance: A Cloudy Perspective. (24252358)
2013
15
Fatty acid correlates of temperament in adolescent boys with attention deficit hyperactivity disorder. (23566869)
2013
16
Sleep promotes consolidation of emotional memory in healthy children but not in children with attention-deficit hyperactivity disorder. (23734235)
2013
17
Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: a meta-analysis. (23735885)
2013
18
Drugs for attention deficit-hyperactivity disorder do not increase the mid-term risk of sudden death in children: a meta-analysis of observational studies. (23669111)
2013
19
Correlation between sleep disorder screening and executive dysfunction in children with attention deficit-hyperactivity disorder. (24394878)
2013
20
Evaluation of attention-deficit hyperactivity disorder risk factors. (24319465)
2013
21
Comorbidity and continuity of attention deficit hyperactivity disorder (ADHD) from childhood to adolescence in Turkey. (23893566)
2013
22
Attention-deficit/hyperactivity disorder: dietary and nutritional treatments. (23806311)
2013
23
Motor examination in children with Attention-deficit/hyperactivity Disorder and Asperger Syndrome. (21824190)
2012
24
Co-morbidity and factor analysis on attention deficit hyperactivity disorder and autism spectrum disorder DSM-IV-derived items. (23267399)
2012
25
Parent-reported attention-deficit hyperactivity disorder and subtypes of conduct disorder as risk factor of recidivism in detained male adolescents. (21420836)
2012
26
Identification of attention-deficit-hyperactivity disorder and conduct disorder in Mexican children by the scale for evaluation of deficit of attention and hyperactivity. (20934222)
2011
27
Genome-wide association study in German patients with attention deficit/hyperactivity disorder. (22012869)
2011
28
Increased symptoms of attention deficit hyperactivity disorder and major depressive disorder symptoms in Nail-patella syndrome: potential association with LMX1B loss-of-function. (21184584)
2011
29
DAT1 and COMT effects on delay discounting and trait impulsivity in male adolescents with attention deficit/hyperactivity disorder and healthy controls. (20736997)
2010
30
Polymorphisms of the steroid sulfatase (STS) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression. (20862695)
2010
31
Attention-deficit hyperactivity disorder and intellectual disability: a study of association with brain-derived neurotrophic factor gene polymorphisms. (20943059)
2010
32
Family-based genome-wide association scan of attention-deficit/hyperactivity disorder. (20732626)
2010
33
Association between homozygosity of a G allele of the alpha-2a-adrenergic receptor gene and methylphenidate response in Korean children and adolescents with attention-deficit/hyperactivity disorder. (19150055)
2009
34
Neurotrophic factor-related gene polymorphisms and adult attention deficit hyperactivity disorder (ADHD) score in a high-risk male population. (18428117)
2008
35
A case-control association study of the polymorphism at the promoter region of the DRD4 gene in Korean boys with attention deficit-hyperactivity disorder: evidence of association with the -521 C/T SNP. (17850946)
2008
36
Dissociated functional brain abnormalities of inhibition in boys with pure conduct disorder and in boys with pure attention deficit hyperactivity disorder. (18413706)
2008
37
Somatosensory evoked potentials in attention deficit/hyperactivity disorder and tic disorder. (17466583)
2007
38
Analysis of the dopamine D4 receptor gene variants in attention deficit hyperactivity disorder]. (17879560)
2007
39
Possible confusion between primary hypersomnia and adult attention-deficit/hyperactivity disorder. (16854470)
2006
40
The dopamine transporter gene and the impulsivity phenotype in attention deficit hyperactivity disorder: a case-control association study in a Korean sample. (16368111)
2006
41
Candidate gene studies of attention-deficit/hyperactivity disorder. (16961425)
2006
42
A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms. (16616730)
2006
43
Attention-deficit/hyperactivity disorder (ADHD) and variable clinical expression of Aarskog-Scott syndrome due to a novel FGD1 gene mutation (R408Q). (15809997)
2005
44
Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder. (16380908)
2005
45
Meta-analysis of candidate genes in attention-deficit hyperactivity disorder]. (16389711)
2005
46
Association between dopamine beta hydroxylase gene and attention deficit hyperactivity disorder complicated with disruptive behavior disorder]. (15796803)
2005
47
Attention deficit hyperactivity disorder with reading disabilities: preliminary genetic findings on the involvement of the ADRA2A gene. (16178932)
2005
48
Association of dopamine beta-hydroxylase polymorphism with attention deficit hyperactivity disorder in children]. (15205702)
2004
49
Dopamine genes and attention-deficit hyperactivity disorder: a review. (12587848)
2003
50
Coloboma mouse mutant as an animal model of hyperkinesis and attention deficit hyperactivity disorder. (10654661)
2000

Variations for Attention Deficit Hyperactivity Disorder

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Expression for genes affiliated with Attention Deficit Hyperactivity Disorder

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Attention Deficit Hyperactivity Disorder

Search GEO for disease gene expression data for Attention Deficit Hyperactivity Disorder.

Pathways for genes affiliated with Attention Deficit Hyperactivity Disorder

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Compounds for genes affiliated with Attention Deficit Hyperactivity Disorder

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GO Terms for genes affiliated with Attention Deficit Hyperactivity Disorder

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Products for genes affiliated with Attention Deficit Hyperactivity Disorder

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Sources for Attention Deficit Hyperactivity Disorder

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet