ADHD
MCID: ATT002
MIFTS: 54

Attention Deficit Hyperactivity Disorder (ADHD) malady

Summaries for Attention Deficit Hyperactivity Disorder

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8Disease Ontology, 33MedlinePlus, 3CDC, 43NINDS, 63Wikipedia, 46OMIM, 32MalaCards
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NINDS:43 Attention deficit-hyperactivity disorder (ADHD) is a neurobehavioral disorder that affects 3-5 percent of all American children. It interferes with a person's ability to stay on a task and to exercise age-appropriate inhibition (cognitive alone or both cognitive and behavioral). Some of the warning signs of ADHD include failure to listen to instructions, inability to organize oneself and school work, fidgeting with hands and feet, talking too much, leaving projects, chores and homework unfinished, and having trouble paying attention to and responding to details. There are several types of ADHD: a predominantly inattentive subtype, a predominantly hyperactive-impulsive subtype, and a combined subtype. ADHD is usually diagnosed in childhood, although the condition can continue into the adult years.

MalaCards: Attention Deficit Hyperactivity Disorder, also known as attention deficit disorder, is related to conduct disorder and autism spectrum disorder. An important gene associated with Attention Deficit Hyperactivity Disorder is DRD4 (dopamine receptor D4). The drugs amphetamine and clonidine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Disease Ontology:8 A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone" and symptoms starting before seven years of age.

MedlinePlus:33 Is it hard for your child to sit still? does your child act without thinking first? does your child start but not finish things? if so, your child may have attention deficit hyperactivity disorder (adhd). nearly everyone shows some of these behaviors at times, but adhd lasts more than 6 months and causes problems in school, at home and in social situations. adhd is more common in boys than girls. it affects 3-5 percent of all american children. the main features of adhd are inattention hyperactivity impulsivity no one knows exactly what causes adhd. it sometimes runs in families, so genetics may be a factor. there may also be environmental factors. a complete evaluation by a trained professional is the only way to know for sure if your child has adhd. treatment may include medicine to control symptoms, therapy, or both. structure at home and at school is important. parent training may also help. nih: national institute of mental health

CDC:3 People with ADHD may have trouble paying attention, controlling impulsive behaviors (may act without thinking about what the result will be), or be overly active. Although ADHD can't be cured, it can be successfully managed and some symptoms may improve as the child ages.

Wikipedia:63 Attention deficit hyperactivity disorder (ADHD, similar to hyperkinetic disorder in the ICD-10) is a... more...

Description from OMIM:46 143465

Aliases & Classifications for Attention Deficit Hyperactivity Disorder

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32MalaCards, 8Disease Ontology, 9diseasecard, 22GTR, 43NINDS, 46OMIM, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

attention deficit hyperactivity disorder 32 8 10 33 60
attention deficit disorder 8 44 60
attention deficit-hyperactivity disorder, susceptibility to 9 22
attention deficit-hyperactivity disorder 43 46
adhd 32 43
attention-deficit hyperactivity disorder 44
hyperkinesis 8


External Ids:

Disease Ontology8 DOID:1094
MeSH34 D001289
SNOMED-CT56 23148009
NCIt39 C35092

Related Diseases for Attention Deficit Hyperactivity Disorder

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Attention Deficit Hyperactivity Disorder:



Diseases related to attention deficit hyperactivity disorder

Clinical Features for Attention Deficit Hyperactivity Disorder

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46OMIM
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Clinical features from OMIM:

143465

Clinical synopsis from OMIM:

143465

Drugs & Therapeutics for Attention Deficit Hyperactivity Disorder

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Attention Deficit Hyperactivity Disorder

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22GTR
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Genetic tests related to Attention Deficit Hyperactivity Disorder:

id Genetic test Affiliating Genes
1 Attention Deficit-Hyperactivity Disorder22

Anatomical Context for Attention Deficit Hyperactivity Disorder

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32MalaCards
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MalaCards organs/tissues related to Attention Deficit Hyperactivity Disorder:

32
Brain, Testes, Eye, Thyroid, Heart, Cortex, Skin, Amygdala, Prefrontal cortex, Cingulate cortex

Animal Models for Attention Deficit Hyperactivity Disorder or affiliated genes

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Publications for Attention Deficit Hyperactivity Disorder

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50PubMed
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Articles related to Attention Deficit Hyperactivity Disorder:

(show top 50)    (show all 1144)
idTitleAuthorsYear
1
Behavioral changes following PCB 153 exposure in the Spontaneously Hypertensive rat - an animal model of Attention-Deficit/Hyperactivity disorder. (24405777)
2014
2
Early-age clinical and developmental features associated to Substance Use Disorders in Attention-Deficit/Hyperactivity Disorder in Adults. (24411652)
2013
3
Family-based association of the brain-derived neurotrophic factor gene in attention-deficit hyperactivity disorder. (23528613)
2013
4
The heritability of clinically diagnosed attention deficit hyperactivity disorder across the lifespan. (24107258)
2013
5
Comparing tomographic EEG neurofeedback and EMG biofeedback in children with attention-deficit/hyperactivity disorder. (24211870)
2013
6
Attention deficit hyperactivity disorder symptoms in adults with autism spectrum disorders. (23788522)
2013
7
Identity status and attachment in adolescents with attention deficit hyperactivity disorder. (24192680)
2013
8
Use of the Children's Communication Checklist-2 for Classification of Language Impairment Risk in Young School-Age Children with Attention-Deficit/Hyperactivity Disorder. (24018696)
2013
9
No cross-sectional and longitudinal association of ferritin and symptoms of attention-deficit-/hyperactivity disorder in a large population-based sample of children: results from the GINIplus and LISAplus studies. (23579923)
2013
10
Response inhibition in preschoolers at familial risk for attention deficit hyperactivity disorder: a behavioral and electrophysiological stop-signal study. (23448499)
2013
11
Event-related oscillations reflect functional asymmetry in children with attention deficit/hyperactivity disorder. (24053046)
2013
12
The Effects of Instructions on Mothers' Ratings of Attention-Deficit/Hyperactivity Disorder Symptoms in Referred Children. (23963544)
2013
13
Cost effectiveness of guanfacine extended-release versus atomoxetine for the treatment of attention-deficit/hyperactivity disorder: application of a matching-adjusted indirect comparison. (23539190)
2013
14
Attention-deficit hyperactivity disorder and the shifting sands of psychiatric nosology. (23908337)
2013
15
Delayed sleep timing and symptoms in adults with attention-deficit/hyperactivity disorder: a controlled actigraphy study. (23445512)
2013
16
Disorder-specific predictive classification of adolescents with attention deficit hyperactivity disorder (ADHD) relative to autism using structural magnetic resonance imaging. (23696841)
2013
17
A 12-week nursing support programme for carers of children and adolescents in the UK with attention deficit hyperactivity disorder prescribed atomoxetine. (24167677)
2013
18
Parent-of-origin effects of FAS and PDLIM1 in attention-deficit/hyperactivity disorder. (21651830)
2012
19
The adverse influence of attention-deficit disorder with or without hyperactivity on cognition in neurofibromatosis type 1. (22881119)
2012
20
Current issues in the diagnosis of attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder. (22035245)
2012
21
Attention-deficit hyperactivity disorder in chronic fatigue syndrome patients. (22648008)
2012
22
Fragile X syndrome and attention-deficit/hyperactivity disorder symptoms. (22196318)
2011
23
Catechol-O-methyltransferase gene rs6267 polymorphism in children with attention deficit hyperactivity disorder]. (21342622)
2011
24
Manganese in children with attention-deficit/hyperactivity disorder: relationship with methylphenidate exposure. (20415606)
2010
25
Association between homozygosity of a G allele of the alpha-2a-adrenergic receptor gene and methylphenidate response in Korean children and adolescents with attention-deficit/hyperactivity disorder. (19150055)
2009
26
Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder. (19906444)
2009
27
Can attention deficit hyperactivity disorder and fetal alcohol spectrum disorder be differentiated by motor and balance deficits? (19345435)
2009
28
Dissociated functional brain abnormalities of inhibition in boys with pure conduct disorder and in boys with pure attention deficit hyperactivity disorder. (18413706)
2008
29
SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder. (18416663)
2008
30
Attentional functions in children and adolescents with attention-deficit/hyperactivity disorder with and without comorbid tic disorder. (17896073)
2008
31
Association analysis of dopamine D4 receptor gene polymorphism and attention deficit hyperactivity disorder with/without disruptive behavior disorder]. (17572775)
2007
32
Motor and gestural performance in children with autism spectrum disorders, developmental coordination disorder, and/or attention deficit hyperactivity disorder. (17286882)
2007
33
Gender-specific association of a functional coding polymorphism in the Neuropeptide S receptor gene with panic disorder but not with schizophrenia or attention-deficit/hyperactivity disorder. (17669576)
2007
34
Serotonin genes and attention deficit/hyperactivity disorder in a Brazilian sample: preferential transmission of the HTR2A 452His allele to affected boys. (16958038)
2007
35
Gene-environment interactions reexamined: does mother's marital stability interact with the dopamine receptor D2 gene in the etiology of childhood attention-deficit/hyperactivity disorder? (17931438)
2007
36
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. (16894395)
2006
37
Meta-analysis of association between a catechol-O-methyltransferase gene polymorphism and attention deficit hyperactivity disorder. (16676224)
2006
38
Schizotypy, attention deficit hyperactivity disorder, and dopamine genes. (17109713)
2006
39
Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis? (16451810)
2006
40
Possible involvement of alpha-2A adrenergic receptors in attention deficit hyperactivity disorder: radioligand binding and polymorphism studies. (16917924)
2006
41
Value of 99mTc-TRODAT-1 SPECT to predict clinical response to methylphenidate treatment in adults with attention deficit hyperactivity disorder. (16894328)
2006
42
Striatal dopamine transporter density in drug naive patients with attention-deficit/hyperactivity disorder. (16479247)
2006
43
No association between attention-deficit hyperactivity disorder and catechol-O-methyltransferase gene in Chinese. (16231731)
2005
44
Clinical significance of tics and attention-deficit hyperactivity disorder (ADHD) in children with pervasive developmental disorder. (15996396)
2005
45
Attention-deficit/hyperactivity disorder, speech delay and polymicrogyria associated with trisomy 18 mosaicism. (15517833)
2004
46
The metaphor and sarcasm scenario test: a new instrument to help differentiate high functioning pervasive developmental disorder from attention deficit/hyperactivity disorder. (15165670)
2004
47
Specificity in the familial aggregation of overt and covert conduct disorder symptoms in a referred attention-deficit hyperactivity disorder sample. (15554581)
2004
48
Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children. (10889550)
2000
49
No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population. (10898897)
2000
50
Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention. (10781080)
2000

Genetic Variations for Attention Deficit Hyperactivity Disorder

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Expression for genes affiliated with Attention Deficit Hyperactivity Disorder

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Attention Deficit Hyperactivity Disorder

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Pathways for genes affiliated with Attention Deficit Hyperactivity Disorder

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Compounds for genes affiliated with Attention Deficit Hyperactivity Disorder

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GO Terms for genes affiliated with Attention Deficit Hyperactivity Disorder

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Products for genes affiliated with Attention Deficit Hyperactivity Disorder

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Sources for Attention Deficit Hyperactivity Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet