MCID: ATS001
MIFTS: 59

Autistic Disorder malady

Categories: Genetic diseases (common), Mental diseases

Aliases & Classifications for Autistic Disorder

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Aliases & Descriptions for Autistic Disorder:

Name: Autistic Disorder 35 11 24 39 13 68
Autism 11 24 27 2 13
Autistic Disorder of Childhood Onset 11 27
Kanner's Syndrome 11
 
Infantile Autism 11
Childhood Autism 11
Autistic 50

Classifications:



Summaries for Autistic Disorder

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Disease Ontology:11 An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.

MalaCards based summary: Autistic Disorder, also known as autism, is related to pervasive developmental disorder and schizophrenia. An important gene associated with Autistic Disorder is CDKL5 (Cyclin Dependent Kinase Like 5), and among its related pathways are Synaptic Neurotransmission Pathways: GABAergic Inhibition and Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics. The drugs fenfluramine hydrochloride and quetiapine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related mouse phenotypes are integument and endocrine/exocrine gland.

Wikipedia:71 Autism is a neurodevelopmental disorder characterized by impaired social interaction, verbal and... more...

Related Diseases for Autistic Disorder

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Diseases related to Autistic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 76)
idRelated DiseaseScoreTop Affiliating Genes
1pervasive developmental disorder30.9FMR1, FOXP2, HTR7, MECP2, SLC6A4
2schizophrenia30.5GABRA5, GABRB3, HTR2A, HTR7, RELN, SLC6A4
3atypical autism29.8CDKL5, EN2, FMR1, GABRB3, MECP2, NLGN3
4mental retardation with language impairment and with or without autistic features12.1
5mental retardation with language impairment and autistic features11.8
6adenylosuccinase deficiency11.2
7pervasive developmental disorder not otherwise specified11.0
8conjunctival degeneration10.8HTR2A, HTR7, SLC6A4
9intrahepatic gall duct cancer10.8HTR7, SLC6A4
10hypoglycemic coma10.8HTR2A, HTR7, SLC6A4
11splenic disease10.8HTR2A, SLC6A4
12vulvar disease10.8GABRB3, HTR2A, SLC6A4
13neurodegeneration with optic atrophy, childhood onset10.7HTR2A, SLC6A4
14asperger syndrome susceptibility, x-linked 210.7
15asperger syndrome susceptibility, x-linked 110.7
16vernal conjunctivitis10.7GABRB3, HTR2A, RELN, SLC6A4
17idiopathic neonatal atrial flutter10.7HTR2A, SLC6A4
18narcolepsy 210.7GABRB3, HTR2A, HTR7, SLC6A4
19autism spectrum disorder10.7
20clcn2-related juvenile myoclonic epilepsy10.6MECP2, UBE3A
21chagas disease10.6HTR2A, SLC6A4
22intravascular angioleiomyoma10.6CDKL5, MECP2
23proton-pump inhibitor-responsive esophageal eosinophilia10.6SNRPN, UBE3A
24enthesopathy10.6HTR2A, OXTR, SLC6A4
25immunodeficiency, isolated10.6FMR1, MECP2, SLC6A4
26central sleep apnea10.6HTR2A, SLC6A4
27dysbaric osteonecrosis10.5GABRB3, SNRPN, UBE3A
28craniosynostosis, adelaide type10.5FMR1, HTR2A, MECP2, SLC6A4
29myopathy with deficiency of iron-sulfur cluster assembly enzyme10.4RELN, TSC2
30angelman syndrome10.4GABRA5, GABRB3, SNRPN, UBE3A
31avoidant personality disorder10.4FMR1, HTR2A, HTR7, MECP2, RELN, SLC6A4
32encephalopathy, neonatal severe10.4CDKL5, GABRB3, MECP2, UBE3A
33adrenoleukodystrophy10.4FMR1, FOXP2
34paraphilia disorder10.4NLGN3, NLGN4X
35albinism, oculocutaneous, type v10.2HTR2A, HTR7, SLC6A4
36familial partial lipodystrophy10.2GABRB3, NLGN3, NLGN4X, OXTR, SLC6A4
37roifman-chitayat syndrome10.2CDKL5, GABRA5, GABRB3, MECP2, SNRPN, UBE3A
38attention deficit-hyperactivity disorder10.0
39intellectual disability9.9
40mutism9.9
41bipolar disorder9.8
42obsessive-compulsive disorder9.7
43epilepsy9.7
44cerebritis9.7
45rubella9.7
46childhood-onset schizophrenia9.7
47cytomegalovirus infection9.7
48obesity9.6
49williams-beuren syndrome9.6
50anorexia nervosa9.6

Graphical network of the top 20 diseases related to Autistic Disorder:



Diseases related to autistic disorder

Symptoms & Phenotypes for Autistic Disorder

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MGI Mouse Phenotypes related to Autistic Disorder according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:001077110.5FMR1, HTR7, MECP2, OXTR, RELN, SLC6A4
2MP:000537910.4CADPS2, FMR1, HTR2A, MECP2, OXTR, SLC6A4
3MP:000301210.4CDKL5, EN2, GABRA5, GABRB3, MECP2, NLGN3
4MP:001076810.1ADSL, CADPS2, EN2, GABRB3, HTR7, MECP2
5MP:000537810.1CADPS2, EN2, FMR1, GABRB3, MECP2, NLGN3
6MP:00036319.8CADPS2, CDKL5, EN2, FMR1, GABRA5, GABRB3
7MP:00053869.7CADPS2, CDKL5, EN2, FMR1, GABRA5, GABRB3
8MP:00053899.4EN2, FMR1, GABRB3, MECP2, NLGN3, OXTR

Drugs & Therapeutics for Autistic Disorder

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Drugs for Autistic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 384)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Aripiprazoleapproved, investigationalPhase 4, Phase 3, Phase 2353129722-12-960795
Synonyms:
129722-12-9
24-29-3
7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-2(1H)-quinolinone
7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydrocarbostyril
7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
AC-1554
AC1L1TXZ
AC1Q3T38
ALKS-9070
Abilify
Abilify (TN)
Abilify Discmelt
Abilitat
Aripiprazol
Aripiprazole
Aripiprazole (JAN/USAN/INN)
Aripiprazole [USAN]
Aripiprazolum
Aripirazole
Arpizol
Asprito|
BMS-337039
Bio-0004
Bristol-Myers Squibb brand of aripiprazole
C094645
C12564
C23H27Cl2N3O2
CHEBI:31236
CHEMBL1112
CID60795
CPD000466383
 
D01164
DB01238
Discmelt
FT-0082572
HMS2051I18
HMS2089M20
HMS2093F22
HSDB 7320
KS-1030
L001339
LS-142666
MLS000759517
MLS001165779
MLS001195621
MLS001424078
MolPort-002-885-808
MolPort-003-844-657
NCGC00159510-02
NCGC00159510-03
OPC 31
OPC-14597
OPC-31
Opc 14597
Otsuka brand of aripiprazole
Pripiprazole
S06-0010
SAM001246750
SMR000466383
STK625160
TL8000707
TL80090184
UNII-82VFR53I78
aripiprazol
aripiprazole
aripiprazolum
||OPC 14597
2
Memantineapproved, investigationalPhase 4, Phase 3, Phase 2, Early Phase 117619982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
3PiracetamapprovedPhase 41707491-74-9
4
DopamineapprovedPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
5
Valproic Acidapproved, investigationalPhase 4, Phase 3, Phase 232299-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico
6
Oxytocinapproved, vet_approvedPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 140850-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
 
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
7
AcetylcysteineapprovedPhase 4, Phase 2316616-91-112035
Synonyms:
(2R)-2-acetylamino-3-Sulfanylpropanoic acid
(R)-2-acetylamino-3-Mercaptopropanoic acid
(R)-Mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
 
Fluprowit
L-Acetylcysteine
L-alpha-acetamido-beta-Mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-ACETYL-L-cysteine
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
8
Minocyclineapproved, investigationalPhase 4, Phase 222410118-90-85281021
Synonyms:
(2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10118-90-8
13614-98-7 (mono-hydrochloride)
4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
4708-96-7
7-Dimethylamino-6-demethyl-6-deoxytetracycline
AC1NQXWM
BRN 3077644
Bio-0062
Borymycin
C07225
C23H27N3O7
CHEBI:50694
CHEBI:529981
CHEMBL1434
CHEMBL259172
CID5281021
CL 59806
CRL-1605 & Minocycline
D05045
HMS2090D03
HSDB 3130
 
LMPK07000002
LS-93850
Lactoferrin B & Minocycline
Lactoferrin H & Minocycline
MINO
MIY
Minociclina
Minociclina [INN-Spanish]
Minociclinum
Minocin
Minocin (Hydrochloride)
Minocline
Minocyclin
Minocycline (USAN/INN)
Minocycline Monohydrochloride
Minocycline [USAN:BAN:INN]
Minocyclinum
Minocyclinum [INN-Latin]
NCGC00178854-01
NSC 141993
NSC141993
UNII-FYY3R43WGO
Vectrin (Hydrochloride)
minociclinum
minocycline
nchembio.559-comp1
9
MilnacipranapprovedPhase 45992623-85-365833
Synonyms:
( -)-Milnacipran
(+-)-cis-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
(-)-milnacipran
(1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide
1-phenyl-1-diethylaminocarbonyl-2-aminomethylcyclopropane HCl
105310-09-6
92623-85-3
AC1L2425
CHEMBL252923
CID65833
D08222
DB04896
F 2207
 
F-2207
F2207
Ixel
LS-178180
Midalcipran
Milnacipran
Milnacipran (INN)
Milnacipran [INN]
Milnacipranum
Milnacipranum [Latin]
Milnacipranum [latin]
NCGC00165825-01
Toledomin
UNII-G56VK1HF36
milnacipran
10
Risperidoneapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 1487106266-06-25073
Synonyms:
106266-06-2
3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
3-(2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl)-2-methyl-6,7,8,9-tetrahydro-pyrido[
3-(2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,
3-[2-[-4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido [1,2-a] pyrimidin-4-one
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperi-dino]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,
3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
AB00514010
AC-1306
AC1L1JJU
BIDD:GT0262
BRD-K53857191-001-04-5
BRN 4891881
Belivon
Bio-0092
Buspirone
C23H27FN4O2
CAS-106266-06-2
CHEBI:8871
CHEMBL85
CID5073
CPD000466323
Consta, Risperdal
D00426
D018967
DB00734
EU-0101074
HMS1571M19
HMS2051H07
HMS2089C22
HSDB 7580
I01-1156
Jsp000573
KS-1106
L000510
LS-134196
Lopac-R-118
MLS000759429
MLS001165758
MLS001424081
MolPort-002-885-858
 
NCGC00015883-01
NCGC00015883-02
NCGC00015883-03
NCGC00094352-01
NCGC00094352-02
NCGC00094352-03
NCGC00179257-01
Prestwick0_001029
Prestwick1_001029
R 62 766
R 64 766, Risperdal, Risperidone
R 64,766
R 64766
R-118
R-64,766
R-64-766
R-64766
R64,766
R64766
Rispen
Risperdal
Risperdal (TN)
Risperdal Consta
Risperdal M-Tab
Risperidal
Risperidal M-Tab
Risperidona
Risperidona [Spanish]
Risperidone
Risperidone (JAN/USAN/INN)
Risperidone (RIS)
Risperidone [USAN:BAN:INN]
Risperidone, placebo
Risperidonum
Risperidonum [Latin]
Risperin
Rispolept
Rispolin
S1615_Selleck
SAM001246595
SMR000466323
SPBio_003078
STK646402
Sequinan
Spiron
TL8000230
UNII-L6UH7ZF8HC
risperdone
risperidone
11
Methylphenidateapproved, investigationalPhase 4, Phase 3, Phase 2373113-45-14158
Synonyms:
.alpha.-Phenyl-2-piperidineacetic acid methyl ester
113-45-1
2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester
2-Piperidineacetic acid, alpha-phenyl-, methyl ester
298-59-9 (hydrochloride)
4311/B Ciba
AC1L1HJM
C 4311
C07196
CHEBI:6887
CHEMBL796
CID4158
Calocain
Centedein
Centedrin
Centedrine
Centredin
Concerta
D-Methylphenidate HCl
D04999
DB00422
DB06701
DEA No. 1724
Daytrana
Daytrana (TN)
EINECS 204-028-6
Focalin
Focalin XR
HSDB 3126
L001307
LS-565
METHYLPHENIDATE (SEE ALSO: METHYLPHENIDATE HYDROCHLORIDE, CAS 298-59-9, NTPNO 10266-R)
MPH
Meridil
Metadate
Metadate CD
Metadate ER
MethyPatch
Methyl (2-phenyl-2-(2-piperidyl)acetate)
Methyl alpha-phenyl-alpha-(2-piperidyl)acetate
Methyl alpha-phenyl-alpha-2-piperidinylacetate
Methyl phenidate
 
Methyl phenidyl acetate
Methyl phenidylacetate
Methylfenidan
Methylin
Methylin ER
Methylofenidan
Methylphen
Methylphenidan
Methylphenidate
Methylphenidate (USAN/INN)
Methylphenidate HCl
Methylphenidate [INN:BAN]
Methylphenidate hydrochloride
Methylphenidatum
Methylphenidatum [INN-Latin]
Methylphenidylacetate hydrochloride
Methypatch
Metilfenidat hydrochloride
Metilfenidato
Metilfenidato [INN-Spanish]
Metilfenidato [Italian]
MolPort-001-779-620
NCI-C56280
PMS-Methylphenidate
Phenidylate
Plimasine
Riphenidate
Ritalin
Ritalin LA
Ritalin SR
Ritalin hydrochloride
Ritalin-SR
Ritaline
Ritcher Works
Ritcher works
Tsentedrin
UNII-207ZZ9QZ49
alpha-Phenyl-2-piperidineacetic acid methyl ester
alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester
d-methylphenidate HCl
methyl 2-phenyl-2-piperidin-2-ylacetate
methyl phenyl(piperidin-2-yl)acetate
methylphenidate
nchembio.2007.55-comp28
12
ZiprasidoneapprovedPhase 4, Phase 3, Phase 2145146939-27-760854
Synonyms:
138982-67-9 (hydrochloride monohydrate)
146939-27-7
5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
5-{2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one
5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one
6-chloro-5-[2-[4-(7-thia-8-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-9-yl)piperazin-1-yl]ethyl]-1,3-dihydroindol-2-one
AC1L1U27
Ambap122883-93-6
BIDD:GT0042
C07568
C21H21ClN4OS
CHEBI:10119
CHEMBL708
CID60854
CP 88059
CP 88059-01
CP-88,059
CP-88,059-01
CP-88,059-1
CP-88059-1
CPD000466328
D08687
DB00246
 
Geodon
Geodon Oral
I14-0766
L000659
LS-83744
MLS000759435
MolPort-003-850-885
SAM001246607
SMR000466328
TL8000889
UNII-6UKA5VEJ6X
Zeldox
Zipradon
Zipradon (TN)
Ziprasidona
Ziprasidone
Ziprasidone (INN)
Ziprasidone [INN:BAN]
Ziprasidone hydrochloride
Ziprasidone mesylate trihydrate
Ziprasidonum
ziprasidona
ziprasidonum
ziprazidone
13
Guanfacineapproved, investigationalPhase 45629110-47-23519
Synonyms:
29110-47-2
29110-48-3 (mono-hydrochloride)
AC1L1G4B
BPBio1_000415
BRD-K32830106-003-03-0
BSPBio_000377
C07037
C9H9Cl2N3O
CAS-29110-48-3
CHEMBL862
CID3519
D08031
DB01018
EINECS 249-442-8
Estulic
Estulic (TN)
G1043_SIGMA
GUANFACINE
Guanfacina
Guanfacina [INN-Spanish]
Guanfacine (INN)
Guanfacine Monohydrochloride
Guanfacine [INN:BAN]
Guanfacinum
 
Guanfacinum [INN-Latin]
Intuniv
L000286
L013430
LS-174236
Lon798
Lopac-G-1043
Lopac0_000519
MolPort-003-941-447
N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
NCGC00015469-01
NCGC00015469-02
NCGC00015469-06
NCGC00024950-01
NCGC00024950-02
NCGC00024950-03
Prestwick0_000339
Prestwick1_000339
Prestwick2_000339
Prestwick3_000339
SPBio_002298
SPD 503
Tocris-1030
UNII-30OMY4G3MK
ZINC03872738
14
Olanzapineapproved, investigationalPhase 4, Phase 2, Phase 3395132539-06-14585
Synonyms:
132539-06-1
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10 H -thieno[2,3- b ] [1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
AC-665
AC1L1IHS
AKOS000282888
ALKS-7921
BIDD:GT0332
BIDD:PXR0138
Bio-0169
C07322
C076029
C17H20N4S
CHEBI:7735
CHEMBL715
CID4585
CPD000466345
D00454
DB00334
Eli Lilly brand of olanzapine
HMS2051H05
HMS2089M04
HMS2093I04
I06-0784
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
Jsp001969
KS-1090
L000455
L005958
LS-152313
LY 170053
LY-170052
 
LY-170053
Lanzac
Lilly brand of olanzapine
MLS000759457
MLS001165781
MLS001195646
MLS001424057
Midax
MolPort-002-885-845
MolPort-003-666-569
MolPort-005-977-341
NCGC00096077-01
NCGC00096077-03
NCGC00096077-04
Olansek
Olanzapin
Olanzapina
Olanzapine
Olanzapine (JAN/USAN/INN)
Olanzapine (OLA)
Olanzapine [USAN:INN]
Olanzapinum
S2493_Selleck
SAM001246652
SMR000466345
SPECTRUM1505024
STK634338
Symbyax
TL8000772
UNII-N7U69T4SZR
Zalasta
Zydis
Zyprexa
Zyprexa (TN)
Zyprexa Intramuscular
Zyprexa Velotab
Zyprexa Zydis
olanzapina
olanzapine
olanzapinum
15
MetforminapprovedPhase 4, Phase 31746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
16
Riluzoleapproved, investigationalPhase 4, Phase 2, Phase 3631744-22-55070
Synonyms:
1744-22-5
2-Amino-6-(trifluoromethoxy)-benzothiazole
2-Amino-6-(trifluoromethoxy)benzothiazole
2-Amino-6-trifluoro- methoxybenzothiazole
2-amino-6-(trifluoromethoxy)-1,3-benzothiazole
2-amino-6-(trifluoromethoxy)benzo[d]thiazole
2-amino-6-(trifluoromethoxyl)benzothiazole
2-amino-6-trifluoromethoxybenzothiazole
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
6-(trifluoromethoxy)benzo[d]thiazol-2-amine
6-Trifluoromethoxy-benzothiazol-2-ylamine
6-trifluoromethoxybenzothiazole-2-yl-amine
AC-730
AC1L1JJL
AC1Q530H
AKOS000265071
ALBB-006046
Amino-2 trifluoromethoxy-6 benzothiazole
Amino-2 trifluoromethoxy-6 benzothiazole [French]
BB_SC-4839
BF-37
BIDD:GT0055
BPBio1_000037
BPBio1_000837
BRD-K21283037-001-02-5
BRD-K21283037-003-03-9
BSPBio_000033
Bio1_000416
Bio1_000905
Bio1_001394
Biomol-NT_000245
C07937
C8H5F3N2OS
CHEMBL744
CID5070
D00775
DB00740
EU-0101064
FT-0082997
HMS1773G08
HMS2089O19
HMS2094G07
I01-2084
LS-40688
 
Lopac-R-116
Lopac0_001064
MLS000069369
MolPort-000-151-262
NCGC00015882-01
NCGC00015882-02
NCGC00015882-03
NCGC00015882-07
NCGC00015882-11
NCGC00023141-02
NCGC00023141-04
NCGC00023141-05
NCGC00023141-06
PK-26124
PK-26124, RP-54274, Rilutek, Riluzole
Prestwick-03A08
Prestwick0_000167
Prestwick1_000167
Prestwick2_000167
Prestwick3_000167
R-116
R116_SIGMA
RP 54274
RP-54274
Rilutek
Rilutek (TN)
Riluzol
Riluzol [INN-Spanish]
Riluzole
Riluzole (JAN/USAN/INN)
Riluzole HCl
Riluzole [USAN:INN]
Riluzolum
Riluzolum [INN-Latin]
S1614_Selleck
SMR000058231
SPBio_000599
SPBio_001954
STK503686
Spectrum2_000550
Tocris-0768
UNII-7LJ087RS6F
ZERO/001785
ZINC00006481
riluzole
17
DonepezilapprovedPhase 4, Phase 1, Phase 2280120014-06-43152
Synonyms:
( inverted exclamation markA)-E 2020
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
120014-06-4
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
AB1004836
AC-6969
AC1L1FAE
AKOS000277311
Aricept
Aricept ODT
C24H29NO3
CHEBI:53289
CHEMBL502
CID3152
D07869
DB00843
Domepezil
Donaz
Donaz (TN)
 
Donepezil
Donepezil (INN)
Donepezil [INN:BAN]
Donepezil hydrochloride
Donepezilo
Donepezilum
Eranz
I06-0343
KBio2_002144
KBio2_004712
KBio2_007280
KBioSS_002144
LS-81819
MolPort-000-881-588
MolPort-003-847-014
NCGC00167537-01
Oprea1_188452
Spectrum5_001662
Spectrum_001664
TL8000531
UNII-8SSC91326P
18
AcetylcholineapprovedPhase 4, Phase 177651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
19
Melatoninapproved, nutraceutical, vet_approvedPhase 4, Phase 2, Phase 3, Phase 125573-31-4896
Synonyms:
0E2B08C1-B325-45B1-8939-6F9081EFDFA4
4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID
5-22-12-00042 (Beilstein Handbook Reference)
5-Methoxy-N-acetyltryptamine
5-methoxy-N-acetyltryptamine
73-31-4
A4039/0172195
AB00053279
AC1L1A9Q
AC1Q4F1W
AC1Q4F1X
AKOS000276269
Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI)
Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI)
Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}
Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}
BAS 01281092
BIDD:ER0618
BPBio1_000590
BRD-K97530723-001-07-6
BRN 0205542
BSPBio_000536
BSPBio_003006
Bio-0635
C01598
CAS-73-31-4
CCRIS 3472
CHEBI:16796
CHEMBL45
CID896
ChemDiv2_003916
Circadin
D008550
D08170
DB01065
DB08189
DivK1c_000353
EINECS 200-797-7
EU-0100787
HMS1380B22
HMS1569K18
HMS1921E04
HMS2089F09
HMS501B15
HSCI1_000400
HSDB 7509
I05-0076
I10-0345
IDI1_000353
IDI1_002631
IN1244
KBio1_000353
KBio2_000665
KBio2_003233
KBio2_005801
KBio3_002226
KBioGR_000591
KBioSS_000665
L001261
LS-1623
Lopac-M-5250
Lopac0_000787
M 5250
M-1200
M-1250
M1105
M5250_SIGMA
ML1
MLS000859594
MLS001055382
MLS001240204
MT6
Mela-T
Melapure
Melatol
Melatonex
Melatonex, Melatonin
Melatonin
Melatonin (synth.) standard-grade
 
Melatonin (synth.) ultra-pure
Melatonina
Melatonina (TN)
Melatonine
Melovine
MolPort-000-737-883
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)-Acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
N-Acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxy-tryptamine Melatonine
N-Acetyl-5-methoxytryptamine
N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]acetamide
N-[2-(5-methoxyindol-3-yl)ethyl]acetamide
N-acetyl-5-methoxy-tryptamine
NCGC00015680-01
NCGC00015680-02
NCGC00015680-03
NCGC00015680-06
NCGC00015680-13
NCGC00090727-01
NCGC00090727-02
NCGC00090727-03
NCGC00090727-04
NCGC00090727-05
NCGC00090727-06
NCGC00090727-07
NCGC00090727-08
NCGC00090727-09
NCI60_004378
NINDS_000353
NMR/14327425
NSC 113928
NSC113928
NSC56423
Nature'S Harmony
Night Rest
Oprea1_104553
Oprea1_814234
PREVENTION 1 (MELATONIN) (PREVENTION 1)
PREVENTION 2 (MELATONIN)
PREVENTION 3 (MELATONIN)
PREVENTION 4 (MELATONIN)
PREVENTION 5 (MELATONIN)
Pineal Hormone
Posidorm
Prestwick0_000458
Prestwick1_000458
Prestwick2_000458
Prestwick3_000458
Prestwick_312
Regulin
Revital Melatonin
Rx Balance
S1204_Selleck
SDCCGMLS-0065812.P001
SDCCGMLS-0065812.P002
SMP2_000309
SMR000326666
SPBio_001527
SPBio_002475
SPECTRUM1500690
STK386880
Sleep Right
Spectrum2_001344
Spectrum3_001393
Spectrum4_000066
Spectrum5_001745
Spectrum_000185
TNP00300
UNII-JL5DK93RCL
Vivitas
WLN: T56 BMJ D2MV1 GO1
ZINC00057060
{N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide
{N-[2-(5-methoxyindol-3-yl)ethyl]-} Acetamide
20
Cholineapproved, nutraceuticalPhase 414862-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
21Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 117734
22GABA AgentsPhase 4, Phase 3, Phase 21622
23Psychotropic DrugsPhase 4, Phase 3, Phase 2, Phase 16279
24Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
25Gastrointestinal AgentsPhase 4, Phase 3, Phase 2, Phase 18109
26Antipsychotic AgentsPhase 4, Phase 3, Phase 2, Phase 12359
27Tranquilizing AgentsPhase 4, Phase 3, Phase 2, Phase 14164
28gamma-GlobulinsPhase 4, Phase 2317
29OxytocicsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 1660
30Antimanic AgentsPhase 4, Phase 3, Phase 2790
31AnticonvulsantsPhase 4, Phase 3, Phase 22620
32Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 112806
33Dopamine AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 13759
34Pharmaceutical SolutionsPhase 4, Phase 3, Phase 2, Early Phase 17793
35ImmunoglobulinsPhase 4, Phase 26045
36Immunoglobulins, IntravenousPhase 4, Phase 2324
37AntibodiesPhase 4, Phase 26045
38Rho(D) Immune GlobulinPhase 4, Phase 2317
39Nootropic AgentsPhase 4, Phase 3, Phase 1, Phase 2701
40Neuroprotective AgentsPhase 4, Phase 2, Phase 31672
41Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
42Excitatory Amino AcidsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 11297
43Excitatory Amino Acid AntagonistsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 11282
44Antiparkinson AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 11527
45EtiracetamPhase 4200
46Protective AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 17190
47Antibiotics, AntitubercularPhase 4, Phase 3, Phase 2, Phase 16972
48Vasodilator AgentsPhase 4, Phase 2, Phase 3, Early Phase 13438
49Anti-Inflammatory AgentsPhase 4, Phase 210355
50Anti-Bacterial AgentsPhase 4, Phase 3, Phase 2, Phase 110884

Interventional clinical trials:

(show top 50)    (show all 759)
idNameStatusNCT IDPhase
1Divalproex Sodium ER in Adult AutismUnknown statusNCT00211796Phase 4
2Study to Evaluate the Efficacy and Safety of AripiprazoleUnknown statusNCT02069977Phase 4
3Levetiracetam Treatment of Children With Subclinical Sleep-Activated Epileptiform Activity (SSEA)Unknown statusNCT00393614Phase 4
4Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART)CompletedNCT01333072Phase 4
5Phase IV Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic DisorderCompletedNCT01227668Phase 4
6A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic DisorderCompletedNCT00576732Phase 4
7Multisite Study: Parental Training Using Video Modelling to Develop Social Skills in Children With AutismCompletedNCT02235467Phase 4
8Minocycline to Treat Childhood Regressive AutismCompletedNCT00409747Phase 4
9FMRI Brain Activation of Aripiprazole Treatment in Autism Spectrum DisordersCompletedNCT01028820Phase 4
10A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum DisordersCompletedNCT01333865Phase 4
11Atomoxetine, Placebo and Parent Management Training in AutismCompletedNCT00844753Phase 4
12Omega-3 Fatty Acids in Autism Spectrum DisordersCompletedNCT01695200Phase 4
13Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum DisorderCompletedNCT00380692Phase 4
14Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of AutismCompletedNCT01337700Phase 4
15A Study of Atomoxetine for Attention Deficit and Hyperactive/Impulsive Behaviour Problems in Children With ASDCompletedNCT00485849Phase 4
16A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in ChildrenCompletedNCT01050582Phase 4
17Methylphenidate Study in Young Children With Developmental DisordersCompletedNCT00517504Phase 4
18Metabolic Effects of Antipsychotics in ChildrenCompletedNCT00205699Phase 4
19Riluzole in Fragile X SyndromeCompletedNCT00895752Phase 4
20Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental DisorderCompletedNCT01238575Phase 4
21An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.CompletedNCT00391261Phase 4
22Treatment With Acetyl-Choline Esterase Inhibitors in Children With Autism Spectrum DisordersRecruitingNCT01098383Phase 4
23Gut to Brain Interaction in Autism. Role of Probiotics on Clinical, Biochemical and Neurophysiological ParametersRecruitingNCT02708901Phase 4
24Understanding the Effects of Intervention on the Brain in AutismRecruitingNCT02680015Phase 4
25Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot StudyRecruitingNCT02255565Phase 4
26Methylphenidate ER Liquid Formulation in Adults With ASD and ADHDRecruitingNCT02096952Phase 4
27An Open-Label Study to Evaluate the Efficacy of High-Dose Gammaplex in Children on the Autism SpectrumActive, not recruitingNCT02199925Phase 4
28The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage SchizophreniaActive, not recruitingNCT01339858Phase 4
29Neural and Behavioral Effects of Oxytocin in Autism Spectrum DisordersEnrolling by invitationNCT02940574Phase 4
30Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum DisordersTerminatedNCT01033565Phase 4
311/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight GainTerminatedNCT01844700Phase 4
32Oxytocin in Adolescents With Autism Spectrum DisordersUnknown statusNCT02007447Phase 2, Phase 3
33Valproate Response in Aggressive Autistic AdolescentsUnknown statusNCT00065884Phase 3
34Self-Injury: Diagnosis and TreatmentUnknown statusNCT00065936Phase 3
35Group Psychoeducational Program for Mothers of Children With High Functional Pervasive Developmental DisordersUnknown statusNCT01243905Phase 2, Phase 3
36Buspirone in the Treatment of 2-6 Year Old Children With Autistic DisorderCompletedNCT00873509Phase 2, Phase 3
37Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With AutismCompletedNCT00498173Phase 3
38A Trial of CM-AT in Children With AutismCompletedNCT00881452Phase 3
39Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)CompletedNCT00332241Phase 3
40A Short Treatment Study of Aripiprazole in Pediatric Patients With Autistic DisorderCompletedNCT01617447Phase 3
41Study of Fluoxetine in AutismCompletedNCT00515320Phase 3
42Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)CompletedNCT00337571Phase 3
43Trial of Methyl B12 on Behavioral and Metabolic Measures in Children With AutismCompletedNCT01039792Phase 2, Phase 3
44A Study to Evaluate the Efficacy and Safety of Risperidone (R064766) in Children and Adolescents With Irritability Associated With Autistic DisorderCompletedNCT01624675Phase 3
45Treatment of Autism in Children and AdolescentsCompletedNCT00005014Phase 3
46Lurasidone Pediatric Autism StudyCompletedNCT01911442Phase 3
47Galantamine Versus Placebo in Childhood AutismCompletedNCT00252603Phase 3
48Open-Label Extension Study of Kuvan for AutismCompletedNCT00943579Phase 2, Phase 3
49Safety and Effectiveness of D-Cycloserine in Children With AutismCompletedNCT00198120Phase 3
50Study of Paliperidone ER in Adolescents and Young Adults With AutismCompletedNCT00549562Phase 3

Search NIH Clinical Center for Autistic Disorder

Inferred drug relations via UMLS68/NDF-RT46:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Autistic Disorder cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Autistic Disorder:
NU211-01/NC215-01, human umbilical cord mesenchymal stem cells for autism
Embryonic/Adult Cultured Cells Related to Autistic Disorder:
Umbilical cord-derived mesenchymal stem cells
Umbilical cord blood-derived mononuclear cells


Cochrane evidence based reviews: autistic disorder

Genetic Tests for Autistic Disorder

About this section

Genetic tests related to Autistic Disorder:

id Genetic test Affiliating Genes
1 Autistic Disorder of Childhood Onset27
2 Autism27
3 Autistic Disorder24 SNRPN

Anatomical Context for Autistic Disorder

About this section

MalaCards organs/tissues related to Autistic Disorder:

36
Brain, Testes, Eye, Bone, Liver, Bone marrow, Cortex

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Autistic Disorder:
id TissueAnatomical CompartmentCell Relevance
1 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate

Publications for Autistic Disorder

About this section

Articles related to Autistic Disorder:

(show top 50)    (show all 420)
idTitleAuthorsYear
1
Serum and cerebrospinal fluid immune mediators in children with autistic disorder: a longitudinal study. (28070266)
2017
2
Lurasidone for the Treatment of Irritability Associated with Autistic Disorder. (26659550)
2016
3
A randomised, double blind, placebo-controlled trial of a fixed dose of N-acetyl cysteine in children with autistic disorder. (27316706)
2016
4
Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study. (27684861)
2016
5
Comparing Efficacy and Side Effects of Memantine vs. Risperidone in the Treatment of Autistic Disorder. (27299475)
2016
6
Effects of augmentation agents in autistic disorder patients treated with risperidone: a systematic review and a meta-analysis. (27409138)
2016
7
Effectiveness of switching from oral ziprasidone to risperidone in a patient with comorbid autistic disorder, profound intellectual disability, Gilbert syndrome, and exacerbation of psychosis. (26938829)
2016
8
Minocycline as Adjunctive Treatment to Risperidone in Children with Autistic Disorder: A Randomized, Double-Blind Placebo-Controlled Trial. (27128958)
2016
9
Pilot Study and Review: Physiological Differences in BDNF, a Potential Biomarker in Males and Females with Autistic Disorder. (26866045)
2015
10
Female patient with autistic disorder, intellectual disability, and co-morbid anxiety disorder: Expanding the phenotype associated with the recurrent 3q13.2-q13.31 microdeletion. (26332054)
2015
11
Kleine-Levin Syndrome in an 8-Year-Old Girl with Autistic Disorder: Does Autism Account a Primary or Secondary Cause? (26664444)
2015
12
Efficacy and Safety of Aripiprazole for Treatment of Irritability in Children with Autistic Disorder: An Open-Label Study. (26538787)
2015
13
Brief Report: Parent-Reported Problems Related to Communication, Behavior and Interests in Children with Autistic Disorder and Their Impact on Quality of Life. (26438642)
2015
14
Risk of cancer in children, adolescents, and young adults with autistic disorder. (25453246)
2015
15
A 6q14.1-q15 microdeletion in a male patient with severe autistic disorder, lack of oral language, and dysmorphic features with concomitant presence of a maternally inherited Xp22.31 copy number gain. (26185640)
2015
16
Transcranial direct current stimulation for hyperactivity and noncompliance in autistic disorder. (25800799)
2015
17
Predictors of quality of life for fathers and mothers of children with Autistic Disorder. (24704547)
2014
18
HPA and SAM axis responses as correlates of self- vs parental ratings of anxiety in boys with an Autistic Disorder. (24412722)
2014
19
The melatonin receptor agonist ramelteon effectively treats insomnia and behavioral symptoms in autistic disorder. (24955274)
2014
20
Psychosocial correlates of parenting a child with autistic disorder. (24731972)
2014
21
Smiling response, stranger anxiety, and autistic disorder. (23872942)
2014
22
A randomised group comparison controlled trial of 'preschoolers with autism': A parent education and skills training intervention for young children with autistic disorder. (22987897)
2014
23
Low rates of depressed mood and depression diagnoses in a clinic review of children and adolescents with autistic disorder. (25198799)
2014
24
Association of 5-HT2A receptor gene polymorphisms with gastrointestinal disorders in Egyptian children with autistic disorder. (25462508)
2014
25
Sedation using 5% lidocaine patches, midazolam and propofol in a combative, obese adolescent with severe autistic disorder undergoing brain magnetic resonance imaging: a case report. (25558344)
2014
26
Effects of risperidone on core symptoms of autistic disorder based on childhood autism rating scale: an open label study. (24701014)
2014
27
Risk of autistic disorder after exposure to general anaesthesia and surgery: A nationwide, retrospective matched cohort study. (25101714)
2014
28
Validation of the World Health Organization's Quality of Life Questionnaire with parents of children with autistic disorder. (24696377)
2014
29
A randomized controlled trial investigating the safety and efficacy of aripiprazole in the long-term maintenance treatment of pediatric patients with irritability associated with autistic disorder. (24502859)
2014
30
Autism Detection in Early Childhood (ADEC): reliability and validity data for a Level 2 screening tool for autistic disorder. (24490680)
2014
31
Ramelteon monotherapy for insomnia and impulsive behavior in high-functioning autistic disorder. (24717259)
2014
32
Risperidone-associated urinary incontinence in patients with autistic disorder with mental retardation. (25118082)
2014
33
Autistic disorder in Nigeria: Profile and challenges to management. (25240124)
2014
34
Riluzole as an adjunctive therapy to risperidone for the treatment of irritability in children with autistic disorder: a double-blind, placebo-controlled, randomized trial. (23821414)
2013
35
Psychosocial interventions for reducing vocal challenging behavior in persons with autistic disorder: a multilevel meta-analysis of single-case experiments. (24183495)
2013
36
An investigation of the security of caregiver attachment during middle childhood in children with high-functioning autistic disorder. (24072664)
2013
37
Aripiprazole treatment of irritability associated with autistic disorder and the relationship between prior antipsychotic exposure, adverse events, and weight change. (24138011)
2013
38
In vitro fertilization and risk of autistic disorder and mental retardation. (23821086)
2013
39
Memantine-induced speech problems in two patients with autistic disorder. (23819879)
2013
40
Epidemiology of autistic disorder in Bahrain: prevalence and obstetric and familial characteristics. (24313037)
2013
41
An open-label extension study of the safety and efficacy of risperidone in children and adolescents with autistic disorder. (24350813)
2013
42
Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status. (24224089)
2013
43
Psychometric properties of the Parenting Stress Index with parents of children with autistic disorder. (23701497)
2013
44
Motor stereotypies and volumetric brain alterations in children with Autistic Disorder. (23637709)
2013
45
Deletion 1q43 encompassing only CHRM3 in a patient with autistic disorder. (23253743)
2013
46
Coping Strategies as Mediators and Moderators between Stress and Quality of Life among Parents of Children with Autistic Disorder. (23868562)
2013
47
Maternal prenatal folic acid supplementation is associated with a reduction in development of autistic disorder. (23796343)
2013
48
Childhood disintegrative disorder: distinction from autistic disorder and predictors of outcome. (23340080)
2013
49
Interpregnancy interval and risk of autistic disorder. (24045716)
2013
50
Biological and psychological rhythms: An integrative approach to rhythm disturbances in autistic disorder. (23542543)
2013

Variations for Autistic Disorder

About this section

Clinvar genetic disease variations for Autistic Disorder:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CDKL5NM_003159.2(CDKL5): c.183delT (p.Met63Cysfs)deletionPathogenicrs62643608GRCh37Chr X, 18593511: 18593511

Copy number variations for Autistic Disorder from CNVD:

6 (show top 50)    (show all 2458)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1137641128000000LossAutism
21390211007558211158005LossAutism
3140981103956056104113271Copy numberAutism
4144241108105015108110680GainVAV3Autism
5146871109988334109993086Deletion or duplicationAutism
6149341111291266111291409LossC1orf103Autism
7152341113734887113735415LossMAGI3Autism
815682111805381207334Copy numberSDF4Autism
9156931118296377118296518GainWDR3Autism
1015989112075681210341Copy numberB3GALT6Autism
1116771113704301429557LossATAD3BAutism
12172841142400000148000000DeletionAutism
13173051142400000148000000DuplicationAutism
14173281142400000148000000Microdeletions and microduplicationsAutism
15173701142600000147000000Copy numberAutism
16173841142600000147000000Deletion or duplicationAutism
17173851142600000147000000Deletion or duplicationAutism
18180341143650000145000000LossAutism
19181281144124744144396898LossAutism
20182041144337336144456849GainAutism
21182731144838594146308287GainBCL9Autism
22183001144943150145824905DuplicationACP6Autism
23183011144943150145824905DuplicationBCL9Autism
24183021144943150145824905DuplicationCHD1LAutism
25183031144943150145824905DuplicationFMO5Autism
26183041144943150145824905DuplicationGJA5Autism
27183051144943150145824905DuplicationPRKAB2Autism
28183181144970329145863421DuplicationAutism
29183331145013719146293282LossAutism
30183741145119362145761156GainAutism
31183901145303997145357746DeletionAutism
32183911145303997145357746Homozyg deletionAutism
33190421148307246148307430GainVPS45Autism
34194431150322696150327314Copy numberS100A5Autism
35195901150822223150852849LossLCE3BAutism
36195911150822223150852849LossLCE3CAutism
37197641151240762151240937LossSPRR3Autism
38199441152055312152055457LossGATAD2BAutism
3921488115909171590971GainCDC2L1Autism
40225641167493526167507362LossNME7Autism
41230291170820885170824528GainC1orf9Autism
42236301172142024172310899GainRC3H1Autism
43237541173697478174026214GainTNRAutism
44240141174300000178600000DuplicationPAPPA2Autism
45240151174300000178600000DuplicationRFWD2Autism
46240281174500555174543675DuplicationPAPPA2Autism
47240291174500555174543675DuplicationRFWD2Autism
48242971178294383178599040LossAutism
49244211180110206180266346LossAutism
50244411180626647180627201LossGLULAutism

Expression for genes affiliated with Autistic Disorder

About this section
Search GEO for disease gene expression data for Autistic Disorder.

Pathways for genes affiliated with Autistic Disorder

About this section

Pathways related to Autistic Disorder according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.3GABRA5, GABRB3
210.2HTR2A, HTR7, SLC6A4

GO Terms for genes affiliated with Autistic Disorder

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Cellular components related to Autistic Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1excitatory synapseGO:006007611.0NLGN3, NLGN4X
2GABA-A receptor complexGO:190271111.0GABRA5, GABRB3
3postsynapseGO:009879410.8FMR1, MECP2, NLGN3
4cell junctionGO:003005410.5CADPS2, FMR1, GABRA5, GABRB3, NLGN3, NLGN4X
5dendriteGO:003042510.5FMR1, GABRA5, HTR2A, NLGN3, NLGN4X, RELN
6integral component of plasma membraneGO:000588710.2GABRA5, GABRB3, HTR2A, HTR7, NLGN3, NLGN4X
7postsynaptic membraneGO:00452119.9CADPS2, FMR1, GABRA5, GABRB3, NLGN4X

Biological processes related to Autistic Disorder according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1inhibitory postsynaptic potentialGO:006008011.0GABRB3, NLGN3
2inner ear receptor cell developmentGO:006011910.9GABRA5, GABRB3
3innervationGO:006038410.9GABRA5, GABRB3
4negative regulation of excitatory postsynaptic potentialGO:009039410.9NLGN3, NLGN4X
5cerebellum developmentGO:002154910.9FOXP2, MECP2, NLGN4X
6positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityGO:200096910.9NLGN3, RELN
7neuron cell-cell adhesionGO:000715810.9NLGN3, NLGN4X
8long-term synaptic potentiationGO:006029110.9MECP2, NLGN3, RELN
9regulation of behaviorGO:005079510.8HTR2A, RELN
10regulation of N-methyl-D-aspartate selective glutamate receptor activityGO:200031010.8NLGN3, RELN
11regulation of respiratory gaseous exchange by neurological system processGO:000208710.8MECP2, NLGN3
12presynaptic membrane assemblyGO:009710510.8NLGN3, NLGN4X
13serotonin receptor signaling pathwayGO:000721010.8HTR2A, HTR7
14learningGO:000761210.8MECP2, NLGN3, NLGN4X, RELN
15sleepGO:003043110.7HTR2A, OXTR
16neuron developmentGO:004866610.7EN2, GABRA5, GABRB3
17positive regulation of synapse assemblyGO:005196510.7MECP2, NLGN3, OXTR
18positive regulation of synaptic transmission, glutamatergicGO:005196810.7NLGN3, OXTR, RELN
19memoryGO:000761310.7HTR2A, MECP2, OXTR, SLC6A4
20negative regulation of neuron apoptotic processGO:004352410.7EN2, GABRA5, GABRB3, MECP2
21sperm ejaculationGO:004271310.7OXTR, SLC6A4
22chemical synaptic transmissionGO:000726810.6GABRA5, HTR2A, HTR7, MECP2, SLC6A4
23vasoconstrictionGO:004231010.6HTR7, SLC6A4
24brain developmentGO:000742010.5GABRA5, MECP2, RELN, SCT, SLC6A4, UBE3A
25social behaviorGO:003517610.4MECP2, NLGN3, NLGN4X, OXTR, SLC6A4
26vocalization behaviorGO:007162510.3NLGN3, NLGN4X

Molecular functions related to Autistic Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled serotonin receptor activityGO:000499310.7HTR2A, HTR7
2GABA-A receptor activityGO:000489010.6GABRA5, GABRB3
3neurexin family protein bindingGO:004204310.5NLGN3, NLGN4X
4siRNA bindingGO:003519710.3FMR1, MECP2

Sources for Autistic Disorder

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet