MCID: ATM007
MIFTS: 18

Autoimmune Disease of Central Nervous System

Categories: Neuronal diseases, Immune diseases

Aliases & Classifications for Autoimmune Disease of Central Nervous System

MalaCards integrated aliases for Autoimmune Disease of Central Nervous System:

Name: Autoimmune Disease of Central Nervous System 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:0060004

Summaries for Autoimmune Disease of Central Nervous System

Disease Ontology : 12 An autoimmune disease of the central nervous system.

MalaCards based summary : Autoimmune Disease of Central Nervous System is related to multifocal motor neuropathy and demyelinating polyneuropathy. An important gene associated with Autoimmune Disease of Central Nervous System is NFASC (Neurofascin), and among its related pathways/superpathways are L1CAM interactions and TNF Superfamily Pathway: Human Ligand-Receptor Interactions and their Associated Functions.

Related Diseases for Autoimmune Disease of Central Nervous System

Diseases in the Nervous System Disease family:

Autoimmune Disease of Central Nervous System Congenital Nervous System Abnormality
Central Nervous System Disease

Diseases related to Autoimmune Disease of Central Nervous System via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 multifocal motor neuropathy 9.9 CD1E CD40LG
2 demyelinating polyneuropathy 9.8 CNTN1 NFASC
3 exanthema subitum 9.6 CD40LG CD86
4 acute myocarditis 9.6 CD86 TNFSF8
5 myocarditis 9.4 CD40LG CD86
6 autoimmune neuropathy 8.9 CD1E CNTN1 CNTNAP1 NFASC TNFSF8

Graphical network of the top 20 diseases related to Autoimmune Disease of Central Nervous System:



Diseases related to Autoimmune Disease of Central Nervous System

Symptoms & Phenotypes for Autoimmune Disease of Central Nervous System

Drugs & Therapeutics for Autoimmune Disease of Central Nervous System

Search Clinical Trials , NIH Clinical Center for Autoimmune Disease of Central Nervous System

Genetic Tests for Autoimmune Disease of Central Nervous System

Anatomical Context for Autoimmune Disease of Central Nervous System

Publications for Autoimmune Disease of Central Nervous System

Variations for Autoimmune Disease of Central Nervous System

Expression for Autoimmune Disease of Central Nervous System

Search GEO for disease gene expression data for Autoimmune Disease of Central Nervous System.

Pathways for Autoimmune Disease of Central Nervous System

GO Terms for Autoimmune Disease of Central Nervous System

Cellular components related to Autoimmune Disease of Central Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.87 CD1E CD40LG CD86 CNTN1 CNTNAP1 NFASC
2 plasma membrane GO:0005886 9.85 CD1E CD40LG CD86 CNTN1 NFASC TNFSF8
3 integral component of plasma membrane GO:0005887 9.56 CD1E CD40LG CNTNAP1 TNFSF8
4 myelin sheath GO:0043209 9.33 CNTN1 CNTNAP1 NFASC
5 paranode region of axon GO:0033270 8.96 CNTNAP1 NFASC
6 paranodal junction GO:0033010 8.62 CNTNAP1 NFASC

Biological processes related to Autoimmune Disease of Central Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.56 CD1E CD40LG CD86 TNFSF8
2 T cell costimulation GO:0031295 9.32 CD40LG CD86
3 paranodal junction assembly GO:0030913 9.16 CNTNAP1 NFASC
4 protein localization to juxtaparanode region of axon GO:0071205 8.96 CNTNAP1 NFASC
5 protein localization to paranode region of axon GO:0002175 8.62 CNTNAP1 NFASC

Molecular functions related to Autoimmune Disease of Central Nervous System according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor binding GO:0005164 8.62 CD40LG TNFSF8

Sources for Autoimmune Disease of Central Nervous System

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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