MCID: ATM020
MIFTS: 26

Autoimmune Enteropathy malady

Rare diseases, Gastrointestinal diseases categories

Summaries for Autoimmune Enteropathy

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Wikipedia:63 Autoimmune enteropathy (AIE) is a rare disorder of the immune system condition that affects infants,... more...

MalaCards based summary: Autoimmune Enteropathy is related to colitis and arthritis. An important gene associated with Autoimmune Enteropathy is USH1C (Usher syndrome 1C (autosomal recessive, severe)), and among its related pathways are Leishmaniasis and Cytokine production by Th17 cells in CF. The compounds nmda and sb 203580 have been mentioned in the context of this disorder. Affiliated tissues include kidney, thyroid and skin, and related mouse phenotype integument.

Aliases & Classifications for Autoimmune Enteropathy

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Autoimmune Enteropathy, Aliases & Descriptions:

Name: Autoimmune Enteropathy 41 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Gastrointestinal diseases


Related Diseases for Autoimmune Enteropathy

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Diseases in the Autoimmune Enteropathy family:

Autoimmune Enteropathy Type 3 Autoimmune Enteropathy Type 2

Diseases related to Autoimmune Enteropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
idRelated DiseaseScoreTop Affiliating Genes
1colitis30.6IL17A, FOXP3
2arthritis29.9FOXP3, CSN1S1, IL17A
3rheumatoid arthritis29.9FOXP3, IL17A, CSN1S1
4thymoma10.3
5autoimmune enteropathy type 310.3
6autoimmune enteropathy type 210.3
7frontonasal dysplasia 110.2
8immunodysregulation, polyendocrinopathy, and enteropathy, x-linked10.2
9hepatitis10.2
10vasculitis10.2
11dermatitis10.1IL17A, FOXP3
12hypersensitivity reaction type ii disease10.1FOXP3, IL17A
13allergic rhinitis10.1FOXP3, IL17A
14food allergy10.1FOXP3, CSN1S1
15diphtheria10.1CSN1S1, FOXP3
16autoimmune disease, multisystem, infantile-onset10.1
17celiac disease10.1
18schimke immunoosseous dysplasia10.1
19autoimmune hepatitis10.1
20glomerulonephritis10.1
21hepatitis c10.1
22atrophic gastritis10.1
23bullous pemphigoid10.1
24duodenitis10.1
25cerebritis10.1
26diarrhea10.1
27gastritis10.1
28lymphopenia10.1
29enteropathy-associated t-cell lymphoma10.1
30atopic dermatitis10.0CSN1S1, IL17A
31usher syndrome10.0USH1C, LNX1
32cholera10.0IL17A, CSN1S1
33cork-handlers' disease10.0IL17A, CSN1S1
34inflammatory bowel disease10.0IL17A, FOXP3
35multiple sclerosis, disease progression, modifier of10.0IL17A, FOXP3
36ulcerative colitis10.0IL17A, CSN1S1
37t-cell leukemia9.9LNX1, FOXP3
38asthma9.9FOXP3, IL17A, CSN1S1
39systemic lupus erythematosus9.8CSN1S1, IL17A
40cystic fibrosis9.8IL17A, LNX1

Graphical network of the top 20 diseases related to Autoimmune Enteropathy:



Diseases related to autoimmune enteropathy

Symptoms for Autoimmune Enteropathy

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Drugs & Therapeutics for Autoimmune Enteropathy

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Drug clinical trials:

Search ClinicalTrials for Autoimmune Enteropathy

Search NIH Clinical Center for Autoimmune Enteropathy

Genetic Tests for Autoimmune Enteropathy

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Anatomical Context for Autoimmune Enteropathy

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MalaCards organs/tissues related to Autoimmune Enteropathy:

31
Kidney, Thyroid, Skin, T cells, Bone

Animal Models for Autoimmune Enteropathy or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Enteropathy:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.7CSN1S1, FOXP3, USH1C

Publications for Autoimmune Enteropathy

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Articles related to Autoimmune Enteropathy:

(show top 50)    (show all 68)
idTitleAuthorsYear
1
Recalcitrant Hypocalcaemia in Autoimmune Enteropathy. (25404718)
2014
2
Abatacept: a new treatment option for refractory adult autoimmune enteropathy. (24045285)
2014
3
Glutamine-supplemented parenteral nutrition and probiotics in four adult autoimmune enteropathy patients. (24827631)
2014
4
Pediatric autoimmune enteropathy: an entity frequently associated with immunodeficiency disorders. (24051695)
2013
5
A Case of Isolated Autoimmune Enteropathy Associated with Autoantibodies to a Novel 28 kilodalton Duodenal Antigen. (23969534)
2013
6
Autoimmune enteropathy: a review and update of clinical management. (22810979)
2012
7
Enteropathy-associated T-cell lymphoma complicating an autoimmune enteropathy. (22226659)
2012
8
Autoimmune enteropathy with a CD8+ CD7- T-cell small bowel intraepithelial lymphocytosis: case report and literature review. (22126605)
2011
9
Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. (19940509)
2010
10
Reduced expression of FOXP3 and regulatory T-cell function in severe forms of early-onset autoimmune enteropathy. (20537998)
2010
11
Cerebral venous thrombosis in autoimmune enteropathy. (20186248)
2010
12
Anti-goblet cell antibodies for the diagnosis of autoimmune enteropathy? (19956142)
2009
13
Autoimmune enteropathy in Swedish children, 1985-2002: a call for strict diagnostic criteria. (18609171)
2008
14
Bone marrow-derived mesenchymal stem cells ameliorate autoimmune enteropathy independently of regulatory T cells. (18420833)
2008
15
Adult autoimmune enteropathy. (18300339)
2008
16
Adult autoimmune enteropathy: Mayo Clinic Rochester experience. (17683994)
2007
17
Severe FOXP3+ and naA^ve T lymphopenia in a non-IPEX form of autoimmune enteropathy combined with an immunodeficiency. (17484867)
2007
18
Association between thymoma and autoimmune enteropathy in adults. (16996380)
2006
19
Enteropathy with loss of enteroendocrine and paneth cells in a patient with immune dysregulation: a case of adult autoimmune enteropathy. (16613334)
2006
20
Autoimmune enteropathy and rheumatoid arthritis: a new association in the field of autoimmunity. (16920048)
2006
21
Adult-onset autoimmune enteropathy in the setting of thymoma successfully treated with infliximab. (15906770)
2005
22
Management of severe refractory adult autoimmune enteropathy with infliximab and tacrolimus. (15785040)
2005
23
Autoimmune enteropathy: molecular concepts. (15703687)
2004
24
Adult autoimmune enteropathy treated successfully with tacrolimus. (14581765)
2003
25
Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide. (12717089)
2003
26
Autoimmune enteropathy. (12952510)
2003
27
Autoimmune enteropathy and colitis in an adult patient. (12924654)
2003
28
Autoimmune enteropathy in an adult with autoimmune multisystemic involvement. (12374224)
2002
29
Mechanisms of villous atrophy in autoimmune enteropathy and coeliac disease. (11982595)
2002
30
Possible autoimmune enteropathy found in autistic children. (12020535)
2002
31
Autoimmune enteropathy in a child: response to infliximab therapy. (11964960)
2002
32
Simultaneous occurrence of autoimmune enteropathy and recurrent deep venous thrombosis. (10749421)
2000
33
Autoimmune enteropathy. (9841709)
1999
34
Thymoma-associated autoimmune enteropathy. A report of two cases. (10587704)
1999
35
Autoimmune enteropathy with distinct mucosal features in T-cell activation deficiency: the contribution of T cells to the mucosal lesion. (10204503)
1999
36
Autoimmune enteropathy with goblet cell antibodies. (10692917)
1999
37
Identification of an autoimmune enteropathy-related 75-kilodalton antigen. (10500064)
1999
38
Autoimmune enteropathy in infants. Pathological study of the disease in two familial cases. (9849864)
1998
39
A 75-kD autoantigen recognized by sera from patients with X-linked autoimmune enteropathy associated with nephropathy. (9528893)
1998
40
Autoimmune enteropathy in Schimke immunoosseous dysplasia. (9632175)
1998
41
Autoimmune enteropathy with severe atrophic gastritis and colitis in an adult: proposal of a generalized autoimmune disorder of the alimentary tract. (9712235)
1998
42
Autoimmune enteropathy in a pediatric patient: partial response to tacrolimus therapy. (9152557)
1997
43
Autoimmune enteropathy in adults. (9314894)
1997
44
Systemic vasculitis complicating infantile autoimmune enteropathy. (7618925)
1995
45
Clinical quiz. A 1.5 year-old boy with autoimmune enteropathy. (7742212)
1995
46
Autoimmune enteropathy with anti-goblet cell antibodies. (7557954)
1995
47
Autoimmune enteropathy, anti-tubular basement membrane antibodies, and glomerulonephritis. (1552411)
1992
48
LFA-1 and ICAM-1 molecule expression in jejunal mucosa from children with autoimmune enteropathy. (1361864)
1992
49
Response to autoimmune enteropathy to cyclosporin A therapy. (1752480)
1991
50
Successful treatment of autoimmune enteropathy with cyclosporine. (2246696)
1990

Variations for Autoimmune Enteropathy

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Expression for genes affiliated with Autoimmune Enteropathy

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Search GEO for disease gene expression data for Autoimmune Enteropathy.

Pathways for genes affiliated with Autoimmune Enteropathy

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Pathways related to Autoimmune Enteropathy according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3IL17A, FOXP3
2
Show member pathways
9.3IL17A, FOXP3

Compounds for genes affiliated with Autoimmune Enteropathy

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Sources:
43Novoseek, 28IUPHAR, 59Tocris Bioscience, 24HMDB
See all sources

Compounds related to Autoimmune Enteropathy according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1nmda43 2810.1LNX1, CSN1S1
2sb 20358043 5910.1IL17A, CSN1S1
3pyrophosphate43 2410.0CSN1S1, LNX1
4ly294002438.7IL17A, CSN1S1
5pge2438.6FOXP3, CSN1S1, IL17A
6tyrosine438.5LNX1, IL17A, CSN1S1

GO Terms for genes affiliated with Autoimmune Enteropathy

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Products for genes affiliated with Autoimmune Enteropathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Autoimmune Enteropathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet