MCID: ATM020
MIFTS: 38

Autoimmune Enteropathy

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Autoimmune Enteropathy

MalaCards integrated aliases for Autoimmune Enteropathy:

Name: Autoimmune Enteropathy 50 69

Classifications:



Summaries for Autoimmune Enteropathy

MalaCards based summary : Autoimmune Enteropathy is related to autoimmune disease, multisystem, infantile-onset, 1 and rheumatoid arthritis. An important gene associated with Autoimmune Enteropathy is IL2RA (Interleukin 2 Receptor Subunit Alpha), and among its related pathways/superpathways are Allograft rejection and Th17 cell differentiation. The drugs Prednisone and Azathioprine have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and kidney, and related phenotypes are digestive/alimentary and hematopoietic system

Wikipedia : 72 Autoimmune enteropathy (AIE) is a rare disorder of the immune system condition that affects infants,... more...

Related Diseases for Autoimmune Enteropathy

Diseases in the Autoimmune Enteropathy family:

Autoimmune Enteropathy Type 3 Autoimmune Enteropathy Type 2

Diseases related to Autoimmune Enteropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Related Disease Score Top Affiliating Genes
1 autoimmune disease, multisystem, infantile-onset, 1 32.1 IL17A STAT3
2 rheumatoid arthritis 27.9 FOXP3 ICAM1 IL17A ITGAL
3 autoimmune enteropathy type 3 11.9
4 autoimmune enteropathy type 2 11.9
5 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 11.1
6 immunodeficiency 41 with lymphoproliferation and autoimmunity 11.0
7 immunodeficiency 31c, autosomal dominant 10.9
8 laryngeal papillomatosis 10.6 IL2RA STAT3
9 paramyloidosis 10.5 IL2RA STAT3
10 cerebral sarcoidosis 10.5 IL2RA STAT3
11 myeloid and lymphoid neoplasms associated with pdgfra rearrangement 10.5 IL17A IL2RA
12 hemolytic anemia due to triosephosphate isomerase deficiency 10.4 FOXP3 IL2RA
13 cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk 10.4 IL17A IL2RA
14 atrichia with papular lesions 10.3 ICAM1 IL2RA
15 dysphagia 10.3 ICAM1 IL2RA
16 epidermolysis bullosa acquisita 10.3 IL17A STAT3
17 autoimmune neuropathy 10.2 FOXP3 ICAM1
18 diabetic macular edema 10.2 ICAM1 IL17A
19 combined cellular and humoral immune defects with granulomas 10.2 FOXP3 IL17A
20 deafness, autosomal recessive 18a 10.2 LNX1 USH1C
21 phaeohyphomycosis 10.2 FOXP3 IL17A
22 anterior corneal pigmentation 10.1 IL17A IL2RA
23 cd3zeta deficiency 10.1 FOXP3 ICAM1
24 vulvar nodular hidradenoma 10.1 IL17A IL2RA STAT3
25 corneal intraepithelial neoplasm 10.0 FOXP3 ICAM1
26 chronic endophthalmitis 10.0 ICAM1 IL17A
27 endometrial clear cell adenocarcinoma 10.0 FOXP3 IL17A STAT3
28 asphyxiating thoracic dystrophy 10.0 FOXP3 IL17A STAT3
29 esophageal candidiasis 10.0 ICAM1 IL17A IL2RA
30 balkan nephropathy 9.9 CSN1S1 FOXP3
31 intestinal disaccharidase deficiency 9.9 ICAM1 IL2RA
32 lymphomatous thyroiditis 9.9 ICAM1 ITGAL
33 churg-strauss syndrome 9.9 ICAM1 IL17A
34 neonatal jaundice 9.9 FOXP3 ICAM1 IL17A
35 moved to 244450 9.9 ICAM1 ITGAL
36 hepatitis 9.8
37 colitis 9.8
38 thymoma 9.8
39 thrombosis 9.7
40 mucositis 9.7
41 vasculitis 9.7
42 epstein-barr virus, susceptibility to chronic infection by 9.7 IL2RA ITGAL STAT3
43 renal tubular acidosis 9.7 ICAM1 IL2RA
44 schimke immunoosseous dysplasia 9.6
45 celiac disease 9.6
46 acrodermatitis enteropathica 9.6
47 down syndrome 9.6
48 arthritis 9.6
49 autoimmune hepatitis 9.6
50 glomerulonephritis 9.6

Graphical network of the top 20 diseases related to Autoimmune Enteropathy:



Diseases related to Autoimmune Enteropathy

Symptoms & Phenotypes for Autoimmune Enteropathy

MGI Mouse Phenotypes related to Autoimmune Enteropathy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.73 STAT3 USH1C FOXP3 ICAM1 IL17A IL2RA
2 hematopoietic system MP:0005397 9.7 ITGAL LNX1 STAT3 FOXP3 ICAM1 IL17A
3 immune system MP:0005387 9.5 ITGAL LNX1 STAT3 FOXP3 ICAM1 IL17A
4 vision/eye MP:0005391 9.02 STAT3 USH1C FOXP3 ICAM1 IL2RA

Drugs & Therapeutics for Autoimmune Enteropathy

Drugs for Autoimmune Enteropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 72)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
2
Azathioprine Approved Phase 4,Phase 3 446-86-6 2265
3 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1
4 Antineoplastic Agents, Hormonal Phase 4,Phase 2
5 glucocorticoids Phase 4,Phase 2
6 Hormone Antagonists Phase 4,Phase 2
7 Hormones Phase 4,Phase 2
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
9 Antibodies Phase 4,Phase 2,Phase 1
10 Antimetabolites Phase 4,Phase 3,Phase 1,Phase 2
11 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 1,Phase 2
12 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1
13 Heptavalent Pneumococcal Conjugate Vaccine Phase 4
14 Immunoglobulins Phase 4,Phase 2,Phase 1
15 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
16 Vaccines Phase 4,Phase 3,Phase 2
17
rituximab Approved Phase 2, Phase 3 174722-31-7 10201696
18
Infliximab Approved Phase 3,Phase 1,Phase 2 170277-31-3
19 Adjuvants, Immunologic Phase 3
20 Dermatologic Agents Phase 3,Phase 1,Phase 2
21 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
22
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
23
Lenograstim Approved Phase 2 135968-09-1
24
Xylometazoline Approved Phase 2 526-36-3 5709
25
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
26
Aldesleukin Approved Phase 2 85898-30-2, 110942-02-4
27
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177
28
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
29
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
30
Adalimumab Approved Phase 1, Phase 2 331731-18-1 16219006
31
Glycerol Approved, Investigational Phase 2 56-81-5 753
32
Calcitriol Approved, Nutraceutical Phase 1, Phase 2 32222-06-3 134070 5280453
33 Alkylating Agents Phase 2
34 6-Mercaptopurine Phase 1, Phase 2
35 Bone Density Conservation Agents Phase 1, Phase 2
36 Calcium, Dietary Phase 1, Phase 2
37 Micronutrients Phase 1, Phase 2
38 Nucleic Acid Synthesis Inhibitors Phase 1, Phase 2
39 Trace Elements Phase 1, Phase 2
40 Vasoconstrictor Agents Phase 1, Phase 2
41 Vitamins Phase 1, Phase 2
42 Interleukin-12 Phase 2
43 Antiemetics Phase 2
44 Autonomic Agents Phase 2
45 BB 1101 Phase 2
46 Dexamethasone acetate Phase 2 1177-87-3
47 HIV Protease Inhibitors Phase 2
48 Peripheral Nervous System Agents Phase 2
49
protease inhibitors Phase 2
50 Analgesics Phase 2

Interventional clinical trials:

(show all 50)

id Name Status NCT ID Phase Drugs
1 Steroid-induced Mood Changes in Patients With Inflammatory Bowel Disease Completed NCT01981889 Phase 4 Prednisone
2 Pneumococcal Vaccination of Crohn Patients Completed NCT01947010 Phase 4
3 Immunogenicity of HPV Vaccine in Immunosuppressed Children Completed NCT02263703 Phase 3
4 Rituximab in Active Ulcerative Colitis Completed NCT00261118 Phase 2, Phase 3 Rituximab
5 Trial Comparing Infliximab and Infliximab and Azathioprine in the Treatment of Patients With Crohn's Disease na�ve to Both Immunomodulators and Biologic Therapy (Study of Biologic and Immunomodulator Naive Patients in Chrohn's Disease: SONIC Completed NCT00094458 Phase 3 infliximab (IFX) placebo infusion; azathioprine (AZA) caps
6 Mesenchymal Stem Cell Therapy for the Treatment of Severe or Refractory Inflammatory and/or Autoimmune Disorders Unknown status NCT01540292 Phase 1, Phase 2
7 A Trial to Determine the Effects of Exercise in Inflammatory Bowel Disease and Rheumatoid Arthritis Unknown status NCT02463916 Phase 2
8 Cyclophosphamide in Treating Young Patients With Severe Autoimmune Enteropathy Completed NCT00258180 Phase 2 cyclophosphamide
9 An Australian Study of Mesenchymal Stromal Cells for Crohn's Disease Completed NCT01090817 Phase 2 Mesenchymal stromal cells (MSC) for infusion
10 Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity Completed NCT00671138 Phase 2
11 Efficacy Study of Targeted, Local Delivery of Drugs to Treat Crohn's Disease Completed NCT00287170 Phase 1, Phase 2 Delayed Release 6MP or Calcitriol vs. Purinethol
12 Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease Completed NCT00138840 Phase 2 STA-5326 mesylate
13 Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease Completed NCT00234741 Phase 2 STA-5326 mesylate
14 Clinical Trial of Gut Microbiota in the Management of Immune Thrombocytopenia Recruiting NCT03033199 Phase 2 Probiotic Agent;Dexamethasone
15 Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases Recruiting NCT01988506 Phase 2 Interleukin 2
16 Sirolimus for Autoimmune Disease of Blood Cells Active, not recruiting NCT00392951 Phase 1, Phase 2 sirolimus
17 Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis Active, not recruiting NCT02647866 Phase 2 KHK4083;Placebo
18 Flu Vaccine Response in Patients on Biologic Therapies Not yet recruiting NCT03277703 Phase 2
19 Fecal Microbiota Transplantation in Depression Not yet recruiting NCT03281044 Phase 2 Fecal microbiota capsules;Placebo oral capsule
20 Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease Terminated NCT00325078 Phase 1, Phase 2 Infliximab
21 Trichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated Syndrome Terminated NCT01413243 Phase 2 Trichuris suis ova
22 An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease Terminated NCT01009281 Phase 2 AIN457
23 Oral AGY for Celiac Disease Completed NCT01765647 Phase 1
24 Antibody Treatment for Advanced Celiac Disease Recruiting NCT01893775 Phase 1
25 Dietary Assessment and Mycotoxin Exposure in Celiac Disease Unknown status NCT01975155
26 Differences in Human Germinal Center B Cell Selection Revealed by Analysis of IgVH Gene Hypermutation and Lineage Trees in Inflammatory Bowel Disease Unknown status NCT00291681
27 Volatile Organic Compounds (VOCs) and Liver Diseases Unknown status NCT01279356
28 Telomere Repair Gene Mutation in Inflammatory Bowel Disease Completed NCT00353639
29 Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive Therapy Completed NCT00727636
30 Abdominal Massage for Bowel Dysfunction Completed NCT03166007
31 Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Psoriasis Completed NCT00658827
32 Enteroscopy for Early Diagnosis of Tumors in Celiac Disease Recruiting NCT02325232
33 Comparison Between Axial- and Lateral-viewing Capsule Endoscopy in Celiac Disease Recruiting NCT03095573
34 The Colonic Microbiome and Mucosal Immunity in Inflammatory Bowel Disease and Ankylosing Spondylitis Recruiting NCT02389075
35 Autoimmune Paradoxical Reactions in IBD Longitudinal Cohort Recruiting NCT02503514
36 Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis Recruiting NCT02908360
37 OTIS Autoimmune Diseases in Pregnancy Project Recruiting NCT01797224
38 Phenomics in Autoimmune and Inflammatory Diseases Recruiting NCT02466217
39 Stelara Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project Recruiting NCT02103361
40 Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases Recruiting NCT02925351
41 The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing Recruiting NCT01280825
42 Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System Recruiting NCT01063309
43 OTIS Autoimmune Diseases in Pregnancy Project Active, not recruiting NCT01086059
44 Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary Active, not recruiting NCT02750800
45 Inflammatory Back Pain and Gluten Free Diet Not yet recruiting NCT03017716
46 Chronic Inflammatory Disease, Lifestyle and Treatment Response Not yet recruiting NCT03173144
47 Does the Human Gut Microbiome Serve as a Novel Personalized Therapeutic Target for Coronary Atherosclerosis? Not yet recruiting NCT03009565
48 Use of PET-CT in the Management of Crohn's Disease Terminated NCT01182467
49 Properties of Mesenchymal Stem Cells in Lung Transplant Terminated NCT01668576
50 T and B Cell Responses in Autoimmune Diseases Terminated NCT01947036

Search NIH Clinical Center for Autoimmune Enteropathy

Genetic Tests for Autoimmune Enteropathy

Anatomical Context for Autoimmune Enteropathy

MalaCards organs/tissues related to Autoimmune Enteropathy:

39
Skin, Thyroid, Kidney, B Cells, Liver, T Cells, Bone

Publications for Autoimmune Enteropathy

Articles related to Autoimmune Enteropathy:

(show top 50) (show all 77)
id Title Authors Year
1
Adult autoimmune enteropathy presenting initially with acquired Acrodermatitis Enteropathica: a case report. ( 28521835 )
2017
2
Seronegative Adult Autoimmune Enteropathy in a Male Traveler. ( 28184376 )
2017
3
Autoimmune enteropathy and hepatitis in pediatric heart transplant recipient. ( 28097735 )
2017
4
A Difficult and Rare Diagnosis of Autoimmune Enteropathy in a Patient Affected by Down Syndrome. ( 27072857 )
2016
5
Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy. ( 27415620 )
2016
6
Severe Malabsorption Refractory to Pancreatic Enzyme Supplementation Unmasking Autoimmune Enteropathy in a Chronic Pancreatitis Patient. ( 27518366 )
2016
7
Autoimmune enteropathy: not all flat mucosa mean coeliac disease. ( 27099674 )
2016
8
Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy. ( 26101883 )
2015
9
Wireless capsule endoscopy as a tool in diagnosing autoimmune enteropathy. ( 26150615 )
2015
10
Abatacept: a new treatment option for refractory adult autoimmune enteropathy. ( 24045285 )
2014
11
Diffuse Autoimmune Enteropathy and Colopathy in an Adult Patient Successfully Treated With Adalimumab and a Review of the Literature. ( 25379737 )
2014
12
Recalcitrant Hypocalcaemia in Autoimmune Enteropathy. ( 25404718 )
2014
13
Autoimmune enteropathy in a 13-year-old celiac girl successfully treated with infliximab. ( 24504079 )
2014
14
Gastrointestinal biopsy findings of autoimmune enteropathy: a review of 25 cases. ( 25188868 )
2014
15
Glutamine-supplemented parenteral nutrition and probiotics in four adult autoimmune enteropathy patients. ( 24827631 )
2014
16
Pediatric autoimmune enteropathy: an entity frequently associated with immunodeficiency disorders. ( 24051695 )
2013
17
A Case of Isolated Autoimmune Enteropathy Associated with Autoantibodies to a Novel 28 kilodalton Duodenal Antigen. ( 23969534 )
2013
18
Mesenchymal stromal cell infusions as rescue therapy for corticosteroid-refractory adult autoimmune enteropathy. ( 22958995 )
2012
19
Autoimmune enteropathy: a review and update of clinical management. ( 22810979 )
2012
20
Enteropathy-associated T-cell lymphoma complicating an autoimmune enteropathy. ( 22226659 )
2012
21
Autoimmune enteropathy with a CD8+ CD7- T-cell small bowel intraepithelial lymphocytosis: case report and literature review. ( 22126605 )
2011
22
Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. ( 19940509 )
2010
23
Cerebral venous thrombosis in autoimmune enteropathy. ( 20186248 )
2010
24
Autoimmune enteropathy associated with cessation of interferon-alpha therapy in chronic hepatitis C. ( 19639409 )
2010
25
Reduced expression of FOXP3 and regulatory T-cell function in severe forms of early-onset autoimmune enteropathy. ( 20537998 )
2010
26
From autoimmune enteropathy to the IPEX (immune dysfunction, polyendocrinopathy, enteropathy, X-linked) syndrome. ( 19912978 )
2009
27
Anti-goblet cell antibodies for the diagnosis of autoimmune enteropathy? ( 19956142 )
2009
28
Autoimmune enteropathy in children and adults. ( 19255930 )
2009
29
Autoimmune enteropathy in Swedish children, 1985-2002: a call for strict diagnostic criteria. ( 18609171 )
2008
30
Clinical and molecular aspects of autoimmune enteropathy and immune dysregulation, polyendocrinopathy autoimmune enteropathy X-linked syndrome. ( 19122524 )
2008
31
Bone marrow-derived mesenchymal stem cells ameliorate autoimmune enteropathy independently of regulatory T cells. ( 18420833 )
2008
32
Adult autoimmune enteropathy. ( 18300339 )
2008
33
Severe FOXP3+ and naA^ve T lymphopenia in a non-IPEX form of autoimmune enteropathy combined with an immunodeficiency. ( 17484867 )
2007
34
Adult autoimmune enteropathy: Mayo Clinic Rochester experience. ( 17683994 )
2007
35
Association between thymoma and autoimmune enteropathy in adults. ( 16996380 )
2006
36
Autoimmune enteropathy and rheumatoid arthritis: a new association in the field of autoimmunity. ( 16920048 )
2006
37
Enteropathy with loss of enteroendocrine and paneth cells in a patient with immune dysregulation: a case of adult autoimmune enteropathy. ( 16613334 )
2006
38
Management of severe refractory adult autoimmune enteropathy with infliximab and tacrolimus. ( 15785040 )
2005
39
Adult-onset autoimmune enteropathy in the setting of thymoma successfully treated with infliximab. ( 15906770 )
2005
40
Autoimmune enteropathy: molecular concepts. ( 15703687 )
2004
41
Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide. ( 12717089 )
2003
42
Induction of remission in a child with autoimmune enteropathy using mycophenolate mofetil. ( 12658040 )
2003
43
Autoimmune enteropathy. ( 12952510 )
2003
44
Adult autoimmune enteropathy treated successfully with tacrolimus. ( 14581765 )
2003
45
Autoimmune enteropathy and colitis in an adult patient. ( 12924654 )
2003
46
Possible autoimmune enteropathy found in autistic children. ( 12020535 )
2002
47
Autoimmune enteropathy in a child: response to infliximab therapy. ( 11964960 )
2002
48
Autoimmune enteropathy in an adult with autoimmune multisystemic involvement. ( 12374224 )
2002
49
Mechanisms of villous atrophy in autoimmune enteropathy and coeliac disease. ( 11982595 )
2002
50
Simultaneous occurrence of autoimmune enteropathy and recurrent deep venous thrombosis. ( 10749421 )
2000

Variations for Autoimmune Enteropathy

Expression for Autoimmune Enteropathy

Search GEO for disease gene expression data for Autoimmune Enteropathy.

Pathways for Autoimmune Enteropathy

Pathways related to Autoimmune Enteropathy according to GeneCards Suite gene sharing:

(show all 19)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 FOXP3 ICAM1 IL17A IL2RA ITGAL
2
Show member pathways
12.21 FOXP3 IL17A IL2RA STAT3
3 12.09 ICAM1 IL2RA ITGAL
4 12.05 FOXP3 IL17A IL2RA STAT3
5 11.96 ICAM1 ITGAL STAT3
6 11.64 ICAM1 IL17A STAT3
7 11.45 ICAM1 IL17A ITGAL
8 11.33 ICAM1 ITGAL
9 11.27 ICAM1 STAT3
10 11.26 ICAM1 ITGAL
11 11.23 FOXP3 IL2RA
12
Show member pathways
11.23 FOXP3 ICAM1 IL17A STAT3
13
Show member pathways
11.19 IL2RA STAT3
14 11.18 ICAM1 ITGAL
15 11.17 ICAM1 STAT3
16
Show member pathways
11.1 FOXP3 IL2RA
17 10.9 IL2RA STAT3
18
Show member pathways
10.9 IL2RA STAT3
19 10.77 FOXP3 ICAM1 IL2RA ITGAL

GO Terms for Autoimmune Enteropathy

Cellular components related to Autoimmune Enteropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 ICAM1 IL17A IL2RA

Biological processes related to Autoimmune Enteropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.46 IL17A IL2RA ITGAL STAT3
2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.43 ICAM1 ITGAL
3 negative regulation of T cell proliferation GO:0042130 9.4 FOXP3 IL2RA
4 T cell homeostasis GO:0043029 9.37 FOXP3 IL2RA
5 leukocyte cell-cell adhesion GO:0007159 9.32 ICAM1 ITGAL
6 negative regulation of immune response GO:0050777 9.26 FOXP3 IL2RA
7 negative regulation of lymphocyte proliferation GO:0050672 8.96 FOXP3 IL2RA
8 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 8.62 ICAM1 ITGAL

Sources for Autoimmune Enteropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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