MCID: ATM011
MIFTS: 58

Autoimmune Hepatitis malady

Categories: Genetic diseases, Rare diseases, Gastrointestinal diseases, Liver diseases, Immune diseases, Skin diseases, Infectious diseases

Aliases & Classifications for Autoimmune Hepatitis

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Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 34LifeMap Discovery®, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Autoimmune Hepatitis:

Name: Autoimmune Hepatitis 34 11 47 53 13
Hepatitis, Autoimmune 38 67
Autoimmune Hepatitis with Centrilobular Necrosis 11
Autoimmune Chronic Active Hepatitis 11
 
Chronic Autoimmune Hepatitis 53
Autoimmune Chronic Hepatitis 47
Hepatitis Autoimmune 49
Aih 47

Characteristics:

Orphanet epidemiological data:

53
autoimmune hepatitis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe),1-9/1000000 (Norway),1-5/10000 (Norway),1-9/1000000 (Sweden),1-5/10000 (New Zealand),1-9/1000000 (Spain),1-5/10000 (Spain),1-5/10000 (Sweden),1-9/1000000 (Israel),1-5/10000 (Israel),1-9/100000 (Denmark),1-5/10000 (Denmark),1-9/100000 (Singapore),1-9/100000; Age of onset: Adult

Classifications:

Orphanet: 53 
Rare hepatic diseases


External Ids:

Disease Ontology11 DOID:2048
ICD1029 K75.4
ICD9CM31 571.42
MeSH38 D019693
Orphanet53 ORPHA2137
UMLS via Orphanet68 C0241910
ICD10 via Orphanet30 K75.4

Summaries for Autoimmune Hepatitis

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Disease Ontology:11 An autoimmune disease of gastrointestinal tract that results in inflammation located in liver caused by the body's immune system attacking the liver cells.

MalaCards based summary: Autoimmune Hepatitis, also known as hepatitis, autoimmune, is related to purpura fulminans and lymphocytic colitis. An important gene associated with Autoimmune Hepatitis is SEPSECS (Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase), and among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and IgA-Producing B Cells in the Intestine. Affiliated tissues include liver, liver and testes, and related mouse phenotypes are liver/biliary system and cardiovascular system.

Wikipedia:70 Autoimmune hepatitis, formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver... more...

Related Diseases for Autoimmune Hepatitis

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Diseases in the Hepatitis family:

Hepatitis C Virus autoimmune hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Autoimmune Hepatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 223)
idRelated DiseaseScoreTop Affiliating Genes
1purpura fulminans29.6HLA-DQB1, HLA-DRB1
2lymphocytic colitis29.2HLA-DQB1, HLA-DRB1
3systemic lupus erythematosus28.0CD40LG, CTLA4, F2, FAS, HLA-DQB1, HLA-DRB1
4hepatitis10.9
5amelogenesis imperfecta hypomaturation type10.8
6progressive locomotor ataxia10.6HLA-A, HLA-DRB1
7fruit allergy10.6HLA-DQB1, HLA-DRB1
8wolffian duct adenocarcinoma10.6HLA-DQB1, HLA-DRB1
9quinquaud's decalvans folliculitis10.6HLA-DQB1, HLA-DRB1
10parsonage turner syndrome10.6HLA-DQB1, HLA-DRB1
11abdominal chemodectomas with cutaneous angiolipomas10.6CTLA4, HLA-DRB1
12myopathy-growth delay-intellectual disability-hypospadias syndrome10.6HLA-DQB1, HLA-DRB1
13peri-anal fistula10.6CTLA4, HLA-DRB1
14vitreoretinochoroidopathy dominant10.6HLA-DQB1, HLA-DRB1
15paraneoplastic pemphigus10.6F2, GPT
16malignant cardiac germ cell tumor10.6HLA-A, HLA-DQB1
17spondylarthropathy10.6HLA-DQB1, HLA-DRB1
18rheumatic myocarditis10.5HLA-DQB1, HLA-DRB1
19antigen-peptide-transporter 2 deficiency10.5CTLA4, HLA-A
20hypercementosis10.5HLA-A, HLA-DRB1
21duodenal disease10.5F2, GPT
22siderosis10.5FAS, HLA-A
23hemophagocytic lymphohistiocytosis10.5CTLA4, HLA-A, HLA-DRB1
24krieble bixler syndrome10.5CTLA4, HLA-DQB1, HLA-DRB1
25dislocation of ear ossicle10.5F2, HLA-A
26thrombophilia due to thrombin defect10.5F2, TPMT
27ovarian papillary cystadenoma10.5HLA-DQB1, HLA-DRB1
28acute lymphocytic leukemia10.4F2, GPT, SEPSECS
29familial periodic paralysis10.4HLA-A, KRT8
30mitochondrial encephalomyopathy10.4HLA-A, HLA-DQB1, HLA-DRB1
31foster-kennedy syndrome10.4HLA-A, HLA-DQB1, HLA-DRB1
32lipodermatosclerosis10.4HLA-A, HLA-DQB1, HLA-DRB1
33intermittent proptosis10.4CTLA4, HLA-A, HLA-DRB1
34aseptic osteitis10.4HLA-A, HLA-DQB1, HLA-DRB1
35sensorineural hearing loss10.4HLA-A, HLA-DQB1, HLA-DRB1
36nebulin-related early-onset distal myopathy10.4HLA-DQB1, HLA-DRB1
37alveolar periostitis10.4F2, GPT
38cirrhotic cardiomyopathy10.4HLA-A, HLA-DQB1, HLA-DRB1
39hepatic coma10.4F2, GPT, HLA-DRB1
40hypoxia10.4CYP2D6, HLA-DQB1, HLA-DRB1
41primary biliary cirrhosis10.4
42pediatric systemic lupus erythematosus10.4FAS, HLA-DQB1, HLA-DRB1
43dentinogenesis imperfecta10.4F2, HLA-A, HLA-DRB1
44autosomal recessive congenital methemoglobinemia10.3AIRE, CTLA4, HLA-DRB1
45panuveitis10.3CTLA4, HLA-DRB1
46chancroid10.3AIRE, CTLA4, HLA-DRB1
47hereditary conventional renal cell carcinoma10.3AIRE, CTLA4, HLA-DRB1
48marek disease10.3CD40LG, F2
49unicentric castleman disease10.3CD40LG, F2
50cd3zeta deficiency10.3AIRE, CTLA4, HLA-A

Graphical network of the top 20 diseases related to Autoimmune Hepatitis:



Diseases related to autoimmune hepatitis

Symptoms for Autoimmune Hepatitis

About this section

Drugs & Therapeutics for Autoimmune Hepatitis

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Drugs for Autoimmune Hepatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 110)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisoloneapproved, vet_approvedPhase 4, Phase 3, Phase 2115350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
2
RibavirinapprovedPhase 498436791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
3
Entecavirapproved, investigationalPhase 4, Phase 3180142217-69-4153941
Synonyms:
142217-69-4
2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one--water (1/1)
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
209216-23-9
6-H-Purin-6-one-,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]
9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine monohydrate
AB1004838
AC-1593
AC1L4BEC
Anhydrous entecavir
BMS-200475
Baraclude
Baraclude (TN)
CHEBI:473990
CHEBI:59902
CHEMBL713
CID153941
 
D04008
D07896
DB00442
ETV
Entecavir
Entecavir (INN)
Entecavir (USAN)
Entecavir (anhydrous)
Entecavir anhydrous
Entecavir hydrate
Entecavir hydrate (JAN)
Entecavirum
FT-0083013
MolPort-005-942-963
S2128_Selleck
SBB066120
SQ-34676
TL8000933
ZINC03802690
entecavir monohydrate
4
SimvastatinapprovedPhase 451079902-63-954454
Synonyms:
(+)-Simvastatin
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
79902-63-9
AC-1530
AC1L1H1F
AKOS005111006
ARONIS24119
BCBcMAP01_000007
BIDD:GT0769
BPBio1_001001
BRD-K22134346-001-05-8
BRN 4768037
BSPBio_000909
BSPBio_002337
Bio-0672
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
C25H38O5
CCRIS 7558
CHEBI:9150
CHEMBL1064
CID54454
CPD000718785
Cholestat
Coledis
Colemin
Corolin
D00434
D019821
DRG-0320
Denan
DivK1c_006991
Eucor
HMS1570N11
HMS1922H13
HMS2089D12
HMS2093E06
HSDB 7208
InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
KBio1_001935
KBio2_002197
KBio2_004765
KBio2_007333
KBio3_001557
KBioGR_001244
KBioSS_002197
KS-1113
Kolestevan
L 644128-000U
LS-46264
Labistatin
Lipex
Lipinorm
Liponorm
Lipovas
Lodales
MK 0733
MK 733
MK-0733
MK-733
MK733
MLS001304029
MLS001333077
MLS001333078
 
MLS002154038
Medipo
Modutrol
MolPort-002-507-345
MolPort-002-885-862
NCGC00017324-01
NCGC00017324-02
NCGC00017324-03
Nivelipol
Nor-Vastina
Pantok
Pepstatin
Prestwick0_000865
Prestwick1_000865
Prestwick2_000865
Prestwick3_000865
Prestwick_171
Rechol
Rendapid
S1792_Selleck
S6196_SIGMA
SAM002589969
SMR000718785
SPBio_001881
SPBio_002830
SPECTRUM1504236
STK801938
Simcor
Simovil
Simvast CR
Simvastatin
Simvastatin & Primycin
Simvastatin (JAN/USP/INN)
Simvastatin [USAN:INN:BAN]
Simvastatin [Usan:Ban:Inn]
Simvastatin lactone
Simvastatin, Compactin
Simvastatina
Simvastatina [Spanish]
Simvastatine
Simvastatine [French]
Simvastatinum
Simvastatinum [Latin]
Simvotin
Sinvacor
Sinvascor
Sivastin
SpecPlus_000895
Spectrum2_001671
Spectrum3_000669
Spectrum4_000632
Spectrum5_001428
Spectrum_001717
Statin
Synvinolin
TNP00259
UNII-AGG2FN16EV
Valemia
Vasotenal
Velostatin
Vytorin
ZINC03780893
Zocor
Zocor (TN)
Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin
Zocord
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta
nchembio790-comp16
simvastatin
5
Methylprednisoloneapproved, vet_approvedPhase 4, Phase 3, Phase 2115383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
6
chloroquineapproved, vet_approvedPhase 414754-05-72719
Synonyms:
( -)-Chloroquine
(+)-Chloroquine
(-)-Chloroquine
(R)-(-)-Chloroquine
3377 RP opalate
3545-67-3
50-63-5
54-05-7
56598-66-4
58175-86-3
58175-87-4
7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline
7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
AB00053436
AC1L1EB8
AC1Q2ZA7
AC1Q2ZA8
Amokin
Aralen
Aralen HCl
Arechin
Arechine
Arequin
Arolen
Arthrochin
Artrichin
Avlochlor
Avloclor
BPBio1_000655
BRD-A91699651-065-01-1
BRN 0482809
BSPBio_000595
BSPBio_002001
Bemaco
Bemaphate
Bemasulph
Benaquin
Bipiquin
C07625
C18H26ClN3
CCRIS 3439
CHEBI:3638
CHEMBL76
CID2719
CQ
CU-01000012392-2
Capquin
Chemochin
Chingamin
Chloraquine
Chlorochin
Chlorochine
Chlorochinum
Chloroin
Chloroquin
Chloroquina
Chloroquine
Chloroquine (USP/INN)
Chloroquine (VAN)
Chloroquine Bis-Phosphoric Acid
Chloroquine Phosphate
Chloroquine [USAN:INN:BAN]
Chloroquine phosphate
Chloroquinium
Chloroquinum
Chloroquinum [INN-Latin]
Chlorquin
Cidanchin
Clorochina
Clorochina [DCIT]
Cloroquina
Cloroquina [INN-Spanish]
Cocartrit
D02366
DB00608
Dawaquin
Delagil
Dichinalex
DivK1c_000404
EINECS 200-191-2
Elestol
Gontochin
Gontochin phosphate
HMS2090O03
HSDB 3029
Heliopar
Hydroxychloroquine Sulfate
IDI1_000404
Imagon
 
Ipsen 225
Iroquine
KBio1_000404
KBio2_000592
KBio2_003160
KBio2_005728
KBio3_001221
KBioGR_000778
KBioSS_000592
Khingamin
Klorokin
LS-141726
Lapaquin
Lopac0_000296
Malaquin
Malaquin (*Diphosphate*)
Malaren
Malarex
Mesylith
Miniquine
MolMap_000009
MolPort-001-783-623
N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine
NCGC00015256-04
NCGC00162120-01
NCI60_000894
NINDS_000404
NSC 187208
NSC14050
NSC187208
Neochin
Nivachine
Nivaquine
Nivaquine B
Pfizerquine
Plaquenil
Prestwick0_000548
Prestwick1_000548
Prestwick2_000548
Prestwick3_000548
Quinachlor
Quinagamin
Quinagamine
Quinercyl
Quingamine
Quinilon
Quinoscan
RP 3377
RP-3377
Resochen
Resochin
Resoquina
Resoquine
Reumachlor
Reumaquin
Rivoquine
Ro 01-6014/N2
Ronaquine
Roquine
SMP2_000034
SN 6718
SN-7618
SPBio_000174
SPBio_002516
ST 21
ST 21 (pharmaceutical)
Sanoquin
Silbesan
Siragan
Solprina
Sopaquin
Spectrum2_000127
Spectrum3_000341
Spectrum4_000279
Spectrum5_000707
Spectrum_000132
Tanakan
Tanakene
Tresochin
Trochin
UNII-886U3H6UFF
W 7618
WIN 244
WLN: T66 BNJ EMY1&3N2&2 IG
chloroquine
nchembio.215-comp4
nchembio.368-comp8
nchembio.87-comp17
{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine
7
Mycophenolic acidapprovedPhase 493924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
8
Mycophenolate mofetilapproved, investigationalPhase 4939128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
9
Prednisoneapproved, vet_approvedPhase 4, Phase 2, Phase 3135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
10
AzathioprineapprovedPhase 4, Phase 2165446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
11
SimeprevirapprovedPhase 496923604-59-566576988
Synonyms:
 
Olysio
12
Etanerceptapproved, investigationalPhase 4, Phase 1, Phase 2397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
13
SofosbuvirapprovedPhase 42281190307-88-045375808
Synonyms:
 
S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate
SOVALDI
14
AdalimumabapprovedPhase 4478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
15
LedipasvirapprovedPhase 4971256388-51-867505836
Synonyms:
 
methyl [(2S)-1-{(6S)-6-[4-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1-oxobutan-2-yl]carbamate
16Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 112770
17Methylprednisolone acetatePhase 4, Phase 3, Phase 21153
18Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
19Prednisolone hemisuccinatePhase 4, Phase 3, Phase 21153
20Antiviral AgentsPhase 4, Phase 39732
21Gastrointestinal AgentsPhase 4, Phase 3, Phase 2, Phase 18109
22Prednisolone phosphatePhase 4, Phase 3, Phase 21153
23Anticholesteremic AgentsPhase 41983
24Prednisolone acetatePhase 4, Phase 3, Phase 21153
25Methylprednisolone HemisuccinatePhase 4, Phase 3, Phase 21153
26Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 212767
27Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110355
28Rosuvastatin CalciumPhase 4459147098-20-2
29Lipid Regulating AgentsPhase 42702
30Anti-Infective AgentsPhase 4, Phase 321402
31HormonesPhase 4, Phase 3, Phase 213979
32Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 1, Phase 26260
33AnalgesicsPhase 4, Phase 3, Phase 1, Phase 211287
34Hypolipidemic AgentsPhase 42721
35Antineoplastic Agents, HormonalPhase 4, Phase 3, Phase 25407
36glucocorticoidsPhase 4, Phase 3, Phase 24920
37Hormone AntagonistsPhase 4, Phase 3, Phase 212778
38AntimetabolitesPhase 4, Phase 211774
39Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110627
40Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41956
41Calcium, DietaryPhase 45525
42
protease inhibitorsPhase 45320
Synonyms:
 
protease inhibitors
43AnthelminticsPhase 4431
44interferonsPhase 42137
45Antiprotozoal AgentsPhase 41986
46Chloroquine diphosphatePhase 414750-63-5
47Antimetabolites, AntineoplasticPhase 4, Phase 27171
48Antiparasitic AgentsPhase 42127
49Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 1, Phase 24295
50AntimalarialsPhase 41216

Interventional clinical trials:

(show top 50)    (show all 65)
idNameStatusNCT IDPhase
1Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol LevelUnknown statusNCT00866229Phase 4
2Possible Role of Chloroquine to Induce a Complete Remission in the Treatment of Autoimmune Hepatitis: a Randomized TrialCompletedNCT02463331Phase 4
3Mycophenolate vs Azathioprin in Autoimmune HepatitisCompletedNCT00687180Phase 4
4CHLOROQUINE FOR MAINTENANCE REMISSION OF AUTOIMMUNE HEPATITISCompletedNCT01980745Phase 4
5SMV + SOF With/Without RBV for IFN-II Patients With CHCCompletedNCT02214420Phase 4
6Anti-TNF Agents for the Treatment of Rheumatoid ArthritisCompletedNCT00837434Phase 4
7Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune HepatitisRecruitingNCT02900443Phase 4
8Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis PatientsRecruitingNCT01907230Phase 4
9Study to Investigate the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 and 4 HCV Infection With Autoimmune DiseaseNot yet recruitingNCT02691728Phase 4
10Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune HepatitisUnknown statusNCT01170351Phase 3
11Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFαUnknown statusNCT01694264Phase 3
12Budesonide 3x3mg/d Versus Prednisone in Active Autoimmune HepatitisCompletedNCT00838214Phase 2, Phase 3
13Clinical Trial in Patients Diagnosed With Immune Thrombocytopenic PurpuraCompletedNCT00699140Phase 3
14Eltrombopag Phase III Study In Chinese Chronic ITP PatientsActive, not recruitingNCT01762761Phase 3
15Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune HepatitisNot yet recruitingNCT02878863Phase 3
16Comparison of Combination Therapy of Corticosteroids and Bovine Colostrum Versus Corticosteroids and Placebo: Randomized Double Blind Placebo Controlled Trial in Treatment of Severe Alcoholic HepatitisNot yet recruitingNCT02473341Phase 3
17Umbilical Cord Mesenchymal Stem Cells for Patients With Autoimmune HepatitisUnknown statusNCT01661842Phase 1, Phase 2
18Oral Administration of Anti-CD3 Monoclonal Antibody in Non-responder Genotype-I Chronic Hepatitis C SubjectsUnknown statusNCT01459419Phase 2
19Evaluation of the Efficacy and Tolerability of Treatment With Interleukin-2 in Severe and Resistant Alopecia AreataUnknown statusNCT01840046Phase 1, Phase 2
20LCP-Tacro vs. Azathioprine for the Treatment of Autoimmune HepatitisCompletedNCT00608894Phase 2
21Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis.CompletedNCT02265328Phase 2
22Liver Test Study of Using JKB-122 in AIH PatientsRecruitingNCT02556372Phase 2
23Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver FailureRecruitingNCT01548690Phase 2
24Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
25Allogeneic Islet Cells Transplanted Onto the OmentumRecruitingNCT02213003Phase 1, Phase 2
26Safety and Efficacy Study of Regulatory T Cells in Treating Autoimmune HepatitisNot yet recruitingNCT02704338Phase 1, Phase 2
27A Single-arm,Phase IIa,Safety and Efficacy Trial of Selected MSCs in the Treatment of Patients With PSC & AiHNot yet recruitingNCT02997878Phase 1, Phase 2
28ASIS for Enbrel in Plaque PsoriasisNot yet recruitingNCT02112097Phase 1, Phase 2
29Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic ImpairmentCompletedNCT00359463Phase 1
30Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing CholangitisRecruitingNCT01088607Phase 1
31sPIF CLINICAL STUDY PROTOCOL FOR AUTOIMMUNE HEPATITISEnrolling by invitationNCT02239562Phase 1
32Autoimmune Hepatitis StudyTerminatedNCT00286663Phase 1
33Volatile Organic Compounds (VOCs) and Liver DiseasesUnknown statusNCT01279356
34Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral HepatitisUnknown statusNCT00160940
35Acupuncture as an Adjunctive Treatment for Hepatitis C PatientsUnknown statusNCT01750515
36Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV InfectionUnknown statusNCT02261662
37Sulfation of Bile Acids as a Biomarker for Hepatobiliary DiseasesUnknown statusNCT01200082
38Breath Test for Patients With Acute Liver Disease for Early Detection of the Need for Transplant or RecoveryUnknown statusNCT01435421
39Effect of High-protein High-fiber Diet in Patients With Autoimmune HepatitisCompletedNCT01655121
40Transient Elastography in Autoimmune HepatitisCompletedNCT01905254
41Immunogenicity and Safety of Vaccinations in Immunocompromised PersonsCompletedNCT01947465
42Collections of Blood and Stool Samples in Patients With Acute HepatitisCompletedNCT00001879
43Plasma Exchange for Autoimmune Autonomic FailureCompletedNCT00359346
44Metabolic Syndrome Feasibility StudyCompletedNCT02287766
45Study to Investigate the Immune Response and Safety of Prophylactic Vaccines in Patients Treated for Multiple SclerosisCompletedNCT02275741
46An Observational Study to Describe in Routine Clinical Practice the Treatment Patterns of Usage of Biological DMARDs in RA Patients.CompletedNCT02590562
47De Novo Autoimmune Hepatitis in Pediatric Liver TransplantationRecruitingNCT02056054
48The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune HepatitisRecruitingNCT02050646
49Study of the Clinical Features of Autoimmune HepatitisRecruitingNCT02994537
50Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap SyndromeRecruitingNCT02936596

Search NIH Clinical Center for Autoimmune Hepatitis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Autoimmune Hepatitis cell therapies at LifeMap Discovery.

Genetic Tests for Autoimmune Hepatitis

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Anatomical Context for Autoimmune Hepatitis

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MalaCards organs/tissues related to Autoimmune Hepatitis:

35
Liver, Testes, T cells, Thyroid, Bone, Bone marrow, Kidney

FMA organs/tissues related to Autoimmune Hepatitis:

17
Liver

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Autoimmune Hepatitis:
id TissueAnatomical CompartmentCell Relevance
1 BloodHematopoietic Bone MarrowHematopoietic Stem Cells Potential therapeutic candidate
2 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate

Animal Models for Autoimmune Hepatitis or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Hepatitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.8AIRE, CTLA4, CYP1A2, FAS, HLA-DQB1, KRT8
2MP:00053857.5CD40LG, CTLA4, CYP1A2, F2, FAS, HLA-DQB1
3MP:00053887.2AIRE, CTLA4, CYP1A2, F2, FAS, HLA-DQB1
4MP:00053977.0AIRE, CD40LG, CTLA4, F2, FAS, GPT

Publications for Autoimmune Hepatitis

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Articles related to Autoimmune Hepatitis:

(show top 50)    (show all 924)
idTitleAuthorsYear
1
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. (27796295)
2016
2
Usefulness of corticosteroids as first-line therapy in patients with acute severe autoimmune hepatitis. (27155529)
2016
3
Seronegative autoimmune hepatitis in children: Spectrum of disorders. (27079745)
2016
4
An update on animal models of autoimmune hepatitis: Are we there yet? (25777755)
2015
5
Type 1 and type 2 autoimmune hepatitis in adults share the same clinical phenotype. (25898847)
2015
6
Hyaline Droplets in Kupffer Cells: A Novel Diagnostic Clue for Autoimmune Hepatitis. (25634746)
2015
7
Role(s) of b cells in autoimmune hepatitis pathogenesis. (26474821)
2015
8
Review article: the prevention and reversal of hepatic fibrosis in autoimmune hepatitis. (24387318)
2014
9
Anti-SLA/LP alone or in combination with anti-Ro52 and fine specificity of anti-Ro52 antibodies in patients with autoimmune hepatitis. (25113420)
2014
10
Regulatory T cells and autoimmune hepatitis: What happens in the liver stays in the liver. (25131772)
2014
11
Diagnostic criteria of autoimmune hepatitis. (24418295)
2014
12
Autoimmune hepatitis on the rise. (24295874)
2013
13
Budesonide versus prednisone with azathioprine for the treatment of autoimmune hepatitis in children and adolescents. (23810723)
2013
14
Anti-nucleosome autoantibodies as markers for autoimmune hepatitis and their correlation with disease activity. (23607768)
2013
15
Autoimmune hepatitis in children: experiences in a tertiary center. (23795253)
2013
16
Autoimmune hepatitis in a patient affected by neuromyelitis optica: A new association. (24070901)
2013
17
Pulmonary and Meningeal Cryptococcosis after Corticosteroid Therapy for Autoimmune Hepatitis: Coexistence of Cryptococci within Pulmonary Cancer Nodule. (23936710)
2013
18
Autoimmune hepatitis associated with leprosy in a child. (22331015)
2013
19
Tfh and plasma cells are correlated with hypergammaglobulinaemia in patients with autoimmune hepatitis. (23826746)
2013
20
Drug choices in autoimmune hepatitis: part A--Steroids. (23061711)
2012
21
The CYP2D6 animal model: how to induce autoimmune hepatitis in mice. (22331063)
2012
22
Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. (22495399)
2012
23
Advanced histology and impaired liver regeneration are associated with disease severity in acute-onset autoimmune hepatitis. (21401703)
2011
24
The benefit of animal models for autoimmune hepatitis. (22117631)
2011
25
Mycophenolate mofetil as a rescue therapy for autoimmune hepatitis patients who are not responsive to standard therapy. (21780898)
2011
26
Requirements and challenges of a preclinical autoimmune hepatitis mouse model. (21894011)
2011
27
Acquired haemophilia A in a woman with autoimmune hepatitis and systemic lupus erythematosus: review of literature. (21885954)
2011
28
Risk factors associated with relapse of type 1 autoimmune hepatitis in Japan. (21711423)
2011
29
Clinical expression of autoimmune hepatitis in a nine-year-old girl with visceral leishmaniasis. (21866471)
2011
30
A case of autoimmune hepatitis with Graves' disease treated by propylthiouracil. (21928702)
2011
31
Reversal of liver cirrhosis in autoimmune hepatitis. (22234080)
2011
32
British Society of Gastroenterology (BSG) guidelines for management of autoimmune hepatitis. (21757447)
2011
33
Another cause of autoimmune hepatitis. (20578154)
2010
34
Uveitis in patients with autoimmune hepatitis. (20346783)
2010
35
Putting flesh and polish on autoimmune hepatitis and moving the disease of exclusion to inclusion. (20879027)
2010
36
Recurrence of autoimmune disease, primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis after liver transplantation. (19876939)
2009
37
Effects of serum aspartate aminotransferase levels in patients with autoimmune hepatitis influence disease course and outcome. (18840547)
2008
38
A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis. (18227818)
2008
39
Scleroderma-like lesions in the course of autoimmune hepatitis. Case report]. (16334539)
2005
40
Use of etanercept in treatment of pyoderma gangrenosum in a patient with autoimmune hepatitis. (16428159)
2005
41
Secondary IgA nephropathy presenting as nephrotic syndrome with glomerular crescentic changes and acute renal failure in a patient with autoimmune hepatitis. (15151269)
2004
42
Diagnostic accuracy of atypical p-ANCA in autoimmune hepatitis using ROC- and multivariate regression analysis. (15546809)
2004
43
A case of autoimmune hepatitis and autoimmune hemolytic anemia following hepatitis A infection. (14655068)
2003
44
HLA genotyping in type-I autoimmune hepatitis in Western India. (14719586)
2003
45
Side effects of budesonide in liver cirrhosis due to chronic autoimmune hepatitis: influence of hepatic metabolism versus portosystemic shunts on a patient complicated with HCC. (14669312)
2003
46
Autoimmune regulator AIRE: evidence for genetic differences between autoimmune hepatitis and hepatitis as part of the autoimmune polyglandular syndrome type 1. (11343230)
2001
47
The liver in collagen diseases: pathologic study of 160 cases with particular reference to hepatic arteritis, primary biliary cirrhosis, autoimmune hepatitis and nodular regenerative hyperplasia of the liver. (11092254)
2000
48
Significant role of apoptosis in type-1 autoimmune hepatitis. (10723202)
1999
49
Remission of experimental autoimmune hepatitis is associated with antigen-specific and non-specific immunosuppression. (8403500)
1993
50
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1. (2466049)
1989

Variations for Autoimmune Hepatitis

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Expression for genes affiliated with Autoimmune Hepatitis

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Search GEO for disease gene expression data for Autoimmune Hepatitis.

Pathways for genes affiliated with Autoimmune Hepatitis

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Pathways related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
19.4CD40LG, CTLA4, PDCD1
29.4CD40LG, CTLA4, PDCD1
39.1CTLA4, HLA-DQB1, HLA-DRB1
49.1CTLA4, HLA-DQB1, HLA-DRB1
5
Show member pathways
8.9HLA-DQB1, HLA-DRB1, PDCD1
6
Show member pathways
8.9CD40LG, CTLA4, FAS, PDCD1
78.9CD40LG, CTLA4, FAS, PDCD1
8
Show member pathways
8.8CD40LG, CTLA4, HLA-DQB1, HLA-DRB1
9
Show member pathways
8.6CTLA4, HLA-DQB1, HLA-DRB1, PDCD1
10
Show member pathways
8.4CD40LG, FAS, HLA-A, HLA-DQB1
117.9CD40LG, CTLA4, HLA-A, HLA-DQB1, HLA-DRB1, PDCD1
12
Show member pathways
7.9CD40LG, CTLA4, FAS, HLA-A, HLA-DQB1, HLA-DRB1

GO Terms for genes affiliated with Autoimmune Hepatitis

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Cellular components related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:00426139.7HLA-DQB1, HLA-DRB1
2integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.4HLA-A, HLA-DQB1, HLA-DRB1
3ER to Golgi transport vesicle membraneGO:00125079.2HLA-A, HLA-DQB1, HLA-DRB1
4external side of plasma membraneGO:00098978.9CD40LG, CTLA4, FAS, PDCD1

Biological processes related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1oxidative demethylationGO:00709899.8CYP1A2, CYP2D6
2heterocycle metabolic processGO:00464839.8CYP1A2, CYP2D6
3drug catabolic processGO:00427379.8CYP1A2, CYP2D6
4alkaloid metabolic processGO:00098209.8CYP1A2, CYP2D6
5monoterpenoid metabolic processGO:00160989.7CYP1A2, CYP2D6
6negative thymic T cell selectionGO:00450609.7AIRE, FAS
7tumor necrosis factor-mediated signaling pathwayGO:00332099.7CD40LG, FAS, KRT8
8interferon-gamma-mediated signaling pathwayGO:00603339.5HLA-A, HLA-DQB1, HLA-DRB1
9hepatocyte apoptotic processGO:00972849.2FAS, KRT8
10immune responseGO:00069558.5AIRE, CTLA4, FAS, HLA-DQB1
11T cell costimulationGO:00312958.3CD40LG, CTLA4, HLA-DQB1, HLA-DRB1, PDCD1

Molecular functions related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenGO:00167129.6CYP1A2, CYP2D6
2peptide antigen bindingGO:00426058.7HLA-A, HLA-DQB1, HLA-DRB1

Sources for Autoimmune Hepatitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet