AIH
MCID: ATM011
MIFTS: 60

Autoimmune Hepatitis (AIH) malady

Categories: Genetic diseases, Rare diseases, Gastrointestinal diseases, Liver diseases, Immune diseases, Skin diseases, Infectious diseases

Aliases & Classifications for Autoimmune Hepatitis

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 35LifeMap Discovery®, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Autoimmune Hepatitis:

Name: Autoimmune Hepatitis 35 11 48 54 13
Hepatitis, Autoimmune 39 68
Autoimmune Hepatitis with Centrilobular Necrosis 11
Autoimmune Chronic Active Hepatitis 11
 
Chronic Autoimmune Hepatitis 54
Autoimmune Chronic Hepatitis 48
Hepatitis Autoimmune 50
Aih 48

Characteristics:

Orphanet epidemiological data:

54
autoimmune hepatitis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe),1-9/1000000 (Norway),1-5/10000 (Norway),1-9/1000000 (Sweden),1-5/10000 (New Zealand),1-9/1000000 (Spain),1-5/10000 (Spain),1-5/10000 (Sweden),1-9/1000000 (Israel),1-5/10000 (Israel),1-9/100000 (Denmark),1-5/10000 (Denmark),1-9/100000 (Singapore),1-9/100000; Age of onset: Adult

Classifications:

Orphanet: 54 
Rare hepatic diseases


External Ids:

Disease Ontology11 DOID:2048
ICD1030 K75.4
ICD9CM32 571.42
MeSH39 D019693
Orphanet54 ORPHA2137
UMLS via Orphanet69 C0241910
ICD10 via Orphanet31 K75.4

Summaries for Autoimmune Hepatitis

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NIH Rare Diseases:48 Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. this immune response causes inflammation of the liver, also called hepatitis. the disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure. autoimmune hepatitis likely results from a combination of autoimmunity, environmental triggers, and a genetic predisposition. it occurs more frequently in females. treatment typically includes corticosteroids and medications that suppress the immune system. in severe cases, a liver transplant may be needed. last updated: 10/1/2016

MalaCards based summary: Autoimmune Hepatitis, also known as hepatitis, autoimmune, is related to hepatitis and cryptococcosis. An important gene associated with Autoimmune Hepatitis is SEPSECS (Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase), and among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and IgA-Producing B Cells in the Intestine. Affiliated tissues include liver, liver and t cells, and related mouse phenotypes are liver/biliary system and reproductive system.

Disease Ontology:11 An autoimmune disease of gastrointestinal tract that results in inflammation located in liver caused by the body's immune system attacking the liver cells.

Wikipedia:71 Autoimmune hepatitis, formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver... more...

Related Diseases for Autoimmune Hepatitis

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Diseases in the Hepatitis family:

Hepatitis C Virus autoimmune hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Autoimmune Hepatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 210)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis31.7CTLA4, HLA-A, HLA-DRB1
2cryptococcosis29.4CD40LG, HLA-DQB1, HLA-DRB1
3amelogenesis imperfecta hypomaturation type10.8
4primary biliary cirrhosis10.4
5sacral nerve root cysts10.3HLA-A, HLA-DRB1
6celiac disease 310.3CTLA4, HLA-DRB1
7familial progressive hyperpigmentation10.3F2, GPT
8apple allergy10.3HLA-DQB1, HLA-DRB1
9non-amyloid monoclonal immunoglobulin deposition disease10.3FAS, HLA-DRB1
10hemoglobin d disease10.3HLA-DQB1, HLA-DRB1
11autosomal dominant intermediate charcot-marie-tooth10.3CTLA4, HLA-DQB1, HLA-DRB1
12bilateral parasagittal parieto-occipital polymicrogyria10.2HLA-DQB1, HLA-DRB1
13fetal hemoglobin quantitative trait locus 310.2CYP2D6, FTCD, SEPSECS
14rete testis adenocarcinoma10.2HLA-A, HLA-DQB1
15learning disability10.2HLA-A, HLA-DQB1, HLA-DRB1
16immune deficiency, familial variable10.2HLA-DQB1, HLA-DRB1
17bickerstaff brainstem encephalitis10.2HLA-A, HLA-DQB1, HLA-DRB1
18noonan-like syndrome with loose anagen hair10.2AIRE, CTLA4
19anaerobic meningitis10.2HLA-A, HLA-DQB1, HLA-DRB1
20folinic acid-responsive seizures10.2HLA-A, HLA-DQB1, HLA-DRB1
21lin-gettig syndrome10.2HLA-DQB1, HLA-DRB1
22complement component 8 deficiency10.2AIRE, CTLA4, HLA-DRB1
23midline interhemispheric variant of holoprosencephaly10.2FAS, HLA-DQB1, HLA-DRB1
24ringed hair10.2GGT1, GPT
25hepatitis a10.2
26cholangitis10.2
27periodontosis10.2AIRE, CTLA4, HLA-A
28choreatic disease10.1CD40LG, HLA-DQB1, HLA-DRB1
29low anorectal malformation10.1CTLA4, F2, HLA-DQB1, HLA-DRB1
30pemphigus vulgaris, familial10.1CD40LG, HLA-A, HLA-DRB1
31freiberg's disease10.1CD40LG, F2
32pseudohypoparathyroidism10.1CD40LG, FAS, HLA-DRB1
33pneumoconiosis due to talc10.1FAS, HLA-A
34sclerosing cholangitis10.1
35hepatitis c10.1
36bile duct cystadenocarcinoma10.1F2, GGT1, GPT
37anterior corneal pigmentation10.1FAS, HLA-A, HLA-DQB1, HLA-DRB1
38gastrointestinal adenoma10.1F2, GGT1, GPT
39paranasal sinus sarcoma10.1F2, GGT1, GPT
40lubinsky syndrome10.1CD40LG, F2
41t-cell prolymphocytic leukemia10.1FAS, HLA-DQB1
42hereditary alpha tryptasemia syndrome10.1CD40LG, F2, GPT, HLA-DRB1
43benign deep fibrous histiocytoma10.1CD40LG, F2, GPT, HLA-DRB1
44parasitic helminthiasis infectious disease10.1CD40LG, HLA-A, HLA-DQB1, HLA-DRB1
45autonomic peripheral neuropathy10.1CD40LG, DLAT, SEPSECS
46depressed scar10.0CD40LG, F2, HLA-A, HLA-DRB1
47inflammatory bowel disease 310.0CD40LG, CTLA4, HLA-A, HLA-DQB1
48maxillary sinusitis10.0CD40LG, CYP2D6, F2, GPT
49hereditary spastic paraplegia10.0CTLA4, F2, GGT1, GPT
50hereditary hemorrhagic telangiectasia10.0F2, GGT1, GPT, SEPSECS

Graphical network of the top 20 diseases related to Autoimmune Hepatitis:



Diseases related to autoimmune hepatitis

Symptoms & Phenotypes for Autoimmune Hepatitis

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MGI Mouse Phenotypes related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.1AIRE, CTLA4, CYP1A2, FAS, HLA-DQB1, KRT8
2MP:00053897.7AIRE, CD40LG, F2, FAS, GGT1, HLA-DQB1
3MP:00053797.7AIRE, CD40LG, CTLA4, CYP1A2, FAS, GGT1
4MP:00053887.4AIRE, CTLA4, CYP1A2, F2, FAS, HLA-DQB1
5MP:00053766.7AIRE, CD40LG, CTLA4, CYP1A2, F2, FAS
6MP:00053976.6AIRE, CD40LG, CTLA4, F2, FAS, GGT1

Drugs & Therapeutics for Autoimmune Hepatitis

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Drugs for Autoimmune Hepatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 111)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etanerceptapproved, investigationalPhase 4, Phase 1, Phase 2403185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
2
SimvastatinapprovedPhase 451979902-63-954454
Synonyms:
(+)-Simvastatin
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
79902-63-9
AC-1530
AC1L1H1F
AKOS005111006
ARONIS24119
BCBcMAP01_000007
BIDD:GT0769
BPBio1_001001
BRD-K22134346-001-05-8
BRN 4768037
BSPBio_000909
BSPBio_002337
Bio-0672
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
C25H38O5
CCRIS 7558
CHEBI:9150
CHEMBL1064
CID54454
CPD000718785
Cholestat
Coledis
Colemin
Corolin
D00434
D019821
DRG-0320
Denan
DivK1c_006991
Eucor
HMS1570N11
HMS1922H13
HMS2089D12
HMS2093E06
HSDB 7208
InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
KBio1_001935
KBio2_002197
KBio2_004765
KBio2_007333
KBio3_001557
KBioGR_001244
KBioSS_002197
KS-1113
Kolestevan
L 644128-000U
LS-46264
Labistatin
Lipex
Lipinorm
Liponorm
Lipovas
Lodales
MK 0733
MK 733
MK-0733
MK-733
MK733
MLS001304029
MLS001333077
MLS001333078
 
MLS002154038
Medipo
Modutrol
MolPort-002-507-345
MolPort-002-885-862
NCGC00017324-01
NCGC00017324-02
NCGC00017324-03
Nivelipol
Nor-Vastina
Pantok
Pepstatin
Prestwick0_000865
Prestwick1_000865
Prestwick2_000865
Prestwick3_000865
Prestwick_171
Rechol
Rendapid
S1792_Selleck
S6196_SIGMA
SAM002589969
SMR000718785
SPBio_001881
SPBio_002830
SPECTRUM1504236
STK801938
Simcor
Simovil
Simvast CR
Simvastatin
Simvastatin & Primycin
Simvastatin (JAN/USP/INN)
Simvastatin [USAN:INN:BAN]
Simvastatin [Usan:Ban:Inn]
Simvastatin lactone
Simvastatin, Compactin
Simvastatina
Simvastatina [Spanish]
Simvastatine
Simvastatine [French]
Simvastatinum
Simvastatinum [Latin]
Simvotin
Sinvacor
Sinvascor
Sivastin
SpecPlus_000895
Spectrum2_001671
Spectrum3_000669
Spectrum4_000632
Spectrum5_001428
Spectrum_001717
Statin
Synvinolin
TNP00259
UNII-AGG2FN16EV
Valemia
Vasotenal
Velostatin
Vytorin
ZINC03780893
Zocor
Zocor (TN)
Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin
Zocord
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta
nchembio790-comp16
simvastatin
3
RibavirinapprovedPhase 4100336791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
4
Methylprednisoloneapproved, vet_approvedPhase 4, Phase 3, Phase 2119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
5
Prednisoloneapproved, vet_approvedPhase 4, Phase 3, Phase 2119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
6
Prednisoneapproved, vet_approvedPhase 4, Phase 2, Phase 3139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
7
chloroquineapproved, vet_approvedPhase 414954-05-72719
Synonyms:
( -)-Chloroquine
(+)-Chloroquine
(-)-Chloroquine
(R)-(-)-Chloroquine
3377 RP opalate
3545-67-3
50-63-5
54-05-7
56598-66-4
58175-86-3
58175-87-4
7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline
7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
AB00053436
AC1L1EB8
AC1Q2ZA7
AC1Q2ZA8
Amokin
Aralen
Aralen HCl
Arechin
Arechine
Arequin
Arolen
Arthrochin
Artrichin
Avlochlor
Avloclor
BPBio1_000655
BRD-A91699651-065-01-1
BRN 0482809
BSPBio_000595
BSPBio_002001
Bemaco
Bemaphate
Bemasulph
Benaquin
Bipiquin
C07625
C18H26ClN3
CCRIS 3439
CHEBI:3638
CHEMBL76
CID2719
CQ
CU-01000012392-2
Capquin
Chemochin
Chingamin
Chloraquine
Chlorochin
Chlorochine
Chlorochinum
Chloroin
Chloroquin
Chloroquina
Chloroquine
Chloroquine (USP/INN)
Chloroquine (VAN)
Chloroquine Bis-Phosphoric Acid
Chloroquine Phosphate
Chloroquine [USAN:INN:BAN]
Chloroquine phosphate
Chloroquinium
Chloroquinum
Chloroquinum [INN-Latin]
Chlorquin
Cidanchin
Clorochina
Clorochina [DCIT]
Cloroquina
Cloroquina [INN-Spanish]
Cocartrit
D02366
DB00608
Dawaquin
Delagil
Dichinalex
DivK1c_000404
EINECS 200-191-2
Elestol
Gontochin
Gontochin phosphate
HMS2090O03
HSDB 3029
Heliopar
Hydroxychloroquine Sulfate
IDI1_000404
Imagon
 
Ipsen 225
Iroquine
KBio1_000404
KBio2_000592
KBio2_003160
KBio2_005728
KBio3_001221
KBioGR_000778
KBioSS_000592
Khingamin
Klorokin
LS-141726
Lapaquin
Lopac0_000296
Malaquin
Malaquin (*Diphosphate*)
Malaren
Malarex
Mesylith
Miniquine
MolMap_000009
MolPort-001-783-623
N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine
NCGC00015256-04
NCGC00162120-01
NCI60_000894
NINDS_000404
NSC 187208
NSC14050
NSC187208
Neochin
Nivachine
Nivaquine
Nivaquine B
Pfizerquine
Plaquenil
Prestwick0_000548
Prestwick1_000548
Prestwick2_000548
Prestwick3_000548
Quinachlor
Quinagamin
Quinagamine
Quinercyl
Quingamine
Quinilon
Quinoscan
RP 3377
RP-3377
Resochen
Resochin
Resoquina
Resoquine
Reumachlor
Reumaquin
Rivoquine
Ro 01-6014/N2
Ronaquine
Roquine
SMP2_000034
SN 6718
SN-7618
SPBio_000174
SPBio_002516
ST 21
ST 21 (pharmaceutical)
Sanoquin
Silbesan
Siragan
Solprina
Sopaquin
Spectrum2_000127
Spectrum3_000341
Spectrum4_000279
Spectrum5_000707
Spectrum_000132
Tanakan
Tanakene
Tresochin
Trochin
UNII-886U3H6UFF
W 7618
WIN 244
WLN: T66 BNJ EMY1&3N2&2 IG
chloroquine
nchembio.215-comp4
nchembio.368-comp8
nchembio.87-comp17
{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine
8
AzathioprineapprovedPhase 4, Phase 2177446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
9
Mycophenolic acidapprovedPhase 495224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
10
Mycophenolate mofetilapproved, investigationalPhase 4952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
11
SofosbuvirapprovedPhase 42591190307-88-045375808
Synonyms:
 
S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate
SOVALDI
12
SimeprevirapprovedPhase 4102923604-59-566576988
Synonyms:
 
Olysio
13
AdalimumabapprovedPhase 4494331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
14
Entecavirapproved, investigationalPhase 4, Phase 3188142217-69-4153941
Synonyms:
142217-69-4
2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one--water (1/1)
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
209216-23-9
6-H-Purin-6-one-,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]
9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine monohydrate
AB1004838
AC-1593
AC1L4BEC
Anhydrous entecavir
BMS-200475
Baraclude
Baraclude (TN)
CHEBI:473990
CHEBI:59902
CHEMBL713
CID153941
 
D04008
D07896
DB00442
ETV
Entecavir
Entecavir (INN)
Entecavir (USAN)
Entecavir (anhydrous)
Entecavir anhydrous
Entecavir hydrate
Entecavir hydrate (JAN)
Entecavirum
FT-0083013
MolPort-005-942-963
S2128_Selleck
SBB066120
SQ-34676
TL8000933
ZINC03802690
entecavir monohydrate
15
LedipasvirapprovedPhase 41071256388-51-867505836
Synonyms:
 
methyl [(2S)-1-{(6S)-6-[4-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1-oxobutan-2-yl]carbamate
16Immunosuppressive AgentsPhase 4, Phase 3, Phase 1, Phase 213086
17Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 123689
18Methylprednisolone HemisuccinatePhase 4, Phase 3, Phase 21193
19Prednisolone phosphatePhase 4, Phase 3, Phase 21193
20Gastrointestinal AgentsPhase 4, Phase 3, Phase 1, Phase 28402
21Anticholesteremic AgentsPhase 42025
22Antiviral AgentsPhase 4, Phase 39967
23Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 213168
24Prednisolone hemisuccinatePhase 4, Phase 3, Phase 21193
25Prednisolone acetatePhase 4, Phase 3, Phase 21193
26Methylprednisolone acetatePhase 4, Phase 3, Phase 21193
27AnalgesicsPhase 4, Phase 3, Phase 1, Phase 211733
28HormonesPhase 4, Phase 3, Phase 214415
29Anti-Infective AgentsPhase 4, Phase 322062
30Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110729
31Rosuvastatin CalciumPhase 4476147098-20-2
32Lipid Regulating AgentsPhase 42766
33AntimetabolitesPhase 4, Phase 212054
34Calcium, DietaryPhase 45713
35Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41998
36Hypolipidemic AgentsPhase 42785
37Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 1, Phase 24443
38Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 1, Phase 26501
39Antirheumatic AgentsPhase 4, Phase 3, Phase 1, Phase 210956
40glucocorticoidsPhase 4, Phase 3, Phase 25103
41Hormone AntagonistsPhase 4, Phase 3, Phase 213180
42Antineoplastic Agents, HormonalPhase 4, Phase 3, Phase 25592
43HIV Protease InhibitorsPhase 45470
44Antimetabolites, AntineoplasticPhase 4, Phase 27361
45AntimalarialsPhase 41246
46Chloroquine diphosphatePhase 414950-63-5
47interferonsPhase 42175
48Antiprotozoal AgentsPhase 42051
49AnthelminticsPhase 4446
50Antiparasitic AgentsPhase 42199

Interventional clinical trials:

(show top 50)    (show all 72)
idNameStatusNCT IDPhase
1Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol LevelUnknown statusNCT00866229Phase 4
2Possible Role of Chloroquine to Induce a Complete Remission in the Treatment of Autoimmune Hepatitis: a Randomized TrialCompletedNCT02463331Phase 4
3Mycophenolate vs Azathioprin in Autoimmune HepatitisCompletedNCT00687180Phase 4
4CHLOROQUINE FOR MAINTENANCE REMISSION OF AUTOIMMUNE HEPATITISCompletedNCT01980745Phase 4
5SMV + SOF With/Without RBV for IFN-II Patients With CHCCompletedNCT02214420Phase 4
6Anti-TNF Agents for the Treatment of Rheumatoid ArthritisCompletedNCT00837434Phase 4
7Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune HepatitisRecruitingNCT02900443Phase 4
8Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis PatientsRecruitingNCT01907230Phase 4
9Study to Investigate the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 and 4 HCV Infection With Autoimmune DiseaseNot yet recruitingNCT02691728Phase 4
10Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune HepatitisUnknown statusNCT01170351Phase 3
11Budesonide 3x3mg/d Versus Prednisone in Active Autoimmune HepatitisCompletedNCT00838214Phase 2, Phase 3
12Clinical Trial in Patients Diagnosed With Immune Thrombocytopenic PurpuraCompletedNCT00699140Phase 3
13Eltrombopag Phase III Study In Chinese Chronic ITP PatientsActive, not recruitingNCT01762761Phase 3
14Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune HepatitisNot yet recruitingNCT02878863Phase 3
15Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled TrialNot yet recruitingNCT02473341Phase 3
16Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFαTerminatedNCT01694264Phase 3
17Umbilical Cord Mesenchymal Stem Cells for Patients With Autoimmune HepatitisUnknown statusNCT01661842Phase 1, Phase 2
18ASIS for Enbrel in Plaque PsoriasisUnknown statusNCT02112097Phase 1, Phase 2
19Oral Administration of Anti-CD3 Monoclonal Antibody in Non-responder Genotype-I Chronic Hepatitis C SubjectsUnknown statusNCT01459419Phase 2
20Evaluation of the Efficacy and Tolerability of Treatment With Interleukin-2 in Severe and Resistant Alopecia AreataUnknown statusNCT01840046Phase 1, Phase 2
21LCP-Tacro vs. Azathioprine for the Treatment of Autoimmune HepatitisCompletedNCT00608894Phase 2
22Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis.CompletedNCT02265328Phase 2
23Liver Test Study of Using JKB-122 in AIH PatientsRecruitingNCT02556372Phase 2
24Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver FailureRecruitingNCT01548690Phase 2
25Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
26Allogeneic Islet Cells Transplanted Onto the OmentumRecruitingNCT02213003Phase 1, Phase 2
27Safety and Efficacy Study of Regulatory T Cells in Treating Autoimmune HepatitisNot yet recruitingNCT02704338Phase 1, Phase 2
28A Single-arm,Phase IIa,Safety and Efficacy Trial of Selected MSCs in the Treatment of Patients With PSC & AiHNot yet recruitingNCT02997878Phase 1, Phase 2
29sPIF CLINICAL STUDY PROTOCOL FOR AUTOIMMUNE HEPATITISCompletedNCT02239562Phase 1
30Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing CholangitisCompletedNCT01088607Phase 1
31Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic ImpairmentCompletedNCT00359463Phase 1
32Autoimmune Hepatitis StudyTerminatedNCT00286663Phase 1
33Volatile Organic Compounds (VOCs) and Liver DiseasesUnknown statusNCT01279356
34Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral HepatitisUnknown statusNCT00160940
35Acupuncture as an Adjunctive Treatment for Hepatitis C PatientsUnknown statusNCT01750515
36Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV InfectionUnknown statusNCT02261662
37Sulfation of Bile Acids as a Biomarker for Hepatobiliary DiseasesUnknown statusNCT01200082
38Breath Test for Patients With Acute Liver Disease for Early Detection of the Need for Transplant or RecoveryUnknown statusNCT01435421
39Effect of High-protein High-fiber Diet in Patients With Autoimmune HepatitisCompletedNCT01655121
40Transient Elastography in Autoimmune HepatitisCompletedNCT01905254
41Immunogenicity and Safety of Vaccinations in Immunocompromised PersonsCompletedNCT01947465
42Collections of Blood and Stool Samples in Patients With Acute HepatitisCompletedNCT00001879
43Plasma Exchange for Autoimmune Autonomic FailureCompletedNCT00359346
44Metabolic Syndrome Feasibility StudyCompletedNCT02287766
45Study to Investigate the Immune Response and Safety of Prophylactic Vaccines in Patients Treated for Multiple SclerosisCompletedNCT02275741
46An Observational Study to Describe in Routine Clinical Practice the Treatment Patterns of Usage of Biological DMARDs in RA Patients.CompletedNCT02590562
47De Novo Autoimmune Hepatitis in Pediatric Liver TransplantationRecruitingNCT02056054
48The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune HepatitisRecruitingNCT02050646
49Mindfulness - Based Stress Reduction and the Relationship on Inflammation in Autoimmune HepatitisRecruitingNCT02950077
50Study of the Clinical Features of Autoimmune HepatitisRecruitingNCT02994537

Search NIH Clinical Center for Autoimmune Hepatitis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Autoimmune Hepatitis cell therapies at LifeMap Discovery.

Genetic Tests for Autoimmune Hepatitis

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Anatomical Context for Autoimmune Hepatitis

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MalaCards organs/tissues related to Autoimmune Hepatitis:

36
Liver, T cells, Testes, Thyroid, Bone, Bone marrow, Kidney

FMA organs/tissues related to Autoimmune Hepatitis:

17
Liver

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Autoimmune Hepatitis:
id TissueAnatomical CompartmentCell Relevance
1 BloodHematopoietic Bone MarrowHematopoietic Stem Cells Potential therapeutic candidate
2 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate

Publications for Autoimmune Hepatitis

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Articles related to Autoimmune Hepatitis:

(show top 50)    (show all 933)
idTitleAuthorsYear
1
Autoimmune Hepatitis Associated with Immune Thrombocytopenic Purpura. (28090042)
2017
2
A Acute hepatitis E mimicking a flare of disease in a patient with chronic autoimmune hepatitis. (28051806)
2017
3
Association of Autoimmune Hepatitis and Celiac Disease: Role of Gluten-Free Diet in Reversing Liver Dysfunction. (28491884)
2017
4
CD24 aggravates acute liver injury in autoimmune hepatitis by promoting IFN-I^ production by CD4(+) T cells. (28065940)
2017
5
Autoimmune hepatitis and eosinophilic granulomatosis with polyangiitis: a rare association. (28108440)
2017
6
IL-17C/IL-17RE Augments T Cell Function in Autoimmune Hepatitis. (27956525)
2017
7
Imaging of autoimmune hepatitis and overlap syndromes. (27999888)
2017
8
Prognostic value of clinical variables and liver histology for development of fibrosis and cirrhosis in autoimmune hepatitis. (27846740)
2017
9
Influence of Liver Inflammation on Liver Stiffness Measurement in Patients with Autoimmune Hepatitis Evaluation by Combinational Elastography. (28056459)
2017
10
Expert clinical management of autoimmune hepatitis in the real world. (28004405)
2016
11
The Management of Autoimmune Hepatitis Patients with Decompensated Cirrhosis: Real-World Experience and a Comprehensive Review. (27515672)
2016
12
Autoimmune hepatitis in a child presenting with hepatopulmonary syndrome (HPS). (26992455)
2016
13
Low-grade elevation of fibrinogen-degradation products is an important parameter to identify acute presentation of autoimmune hepatitis. (27161820)
2016
14
Autoimmune hepatitis: From mechanisms to therapy. (27161382)
2016
15
Editorial: autoimmune hepatitis - identifying options forA treatment. Authors' reply. (27137726)
2016
16
The Use of Tacrolimous in Refractory Autoimmune Hepatitis in Children and Adults: A Single Center Experience. (27633047)
2016
17
Exploring the Role of Killer Cell Immunoglobulin-Like Receptors and Their HLA Class I Ligands in Autoimmune Hepatitis. (26744892)
2016
18
Evaluate of transient elastography in assessing liver fibrosis in patients with autoimmune hepatitis. (27505153)
2016
19
Autoimmune hepatitis following drug-induced liver injury in an elderly patient. (27170297)
2016
20
Autoimmune hepatitis: an uncommon presentation of thymoma. (27079907)
2016
21
Toxin-Induced Autoimmune Hepatitis Caused by Raw Cashew Nuts. (27807585)
2016
22
Pregnancy with autoimmune hepatitis. (27458515)
2016
23
Concurrent extrahepatic autoimmunity in autoimmune hepatitis: implications for diagnosis, clinical course and long-term outcomes. (27541063)
2016
24
The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model. (27414259)
2016
25
Editorial: autoimmune hepatitis - identifying options for treatment. (27137725)
2016
26
Case Report of Sweet's Syndrome Associated With Autoimmune Hepatitis. (27534778)
2016
27
Anaerococcus urinomassiliensis sp. nov., isolated from a urine sample of a 17-year-old boy affected by autoimmune hepatitis and membranoproliferative glomerulonephritis. (27408746)
2016
28
Contemporary issues and future directions in autoimmune hepatitis. (27215278)
2016
29
The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes. (26890333)
2016
30
Corrigendum to "Autoimmune Hepatitis: Progress from Global Immunosuppression to Personalised Regulatory T Cell Therapy". (27990413)
2016
31
Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on DCs-CD8(+) T cells communication. (27639182)
2016
32
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. (27796295)
2016
33
Transient Expression of Transgenic IL-12 in Mouse Liver Triggers Unremitting Inflammation Mimicking Human Autoimmune Hepatitis. (27511737)
2016
34
Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis. (27516526)
2016
35
Protocol of a prospective study for the combination treatment of Shu-Gan-jian-Pi decoction and steroid standard therapy in autoimmune hepatitis patients. (27923369)
2016
36
Autoantibody presentation in drug-induced liver injury and idiopathic autoimmune hepatitis: the influence of human leucocyte antigen alleles. (27206238)
2016
37
IL4 gene polymorphisms in Iranian patients with autoimmune hepatitis. (26735262)
2016
38
Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells. (27183637)
2016
39
Nonalcoholic Fatty Liver Disease in Patients with Autoimmune Hepatitis: Further Reason for Teeth GNASHing? (27468739)
2016
40
Increasing incidence of elderly-onset autoimmune hepatitis. (27531184)
2016
41
Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan. (27406031)
2016
42
Autoimmune hepatitis in Pakistan. (27924956)
2016
43
Strongyloides stercoralis hyperinfection in patient with autoimmune hepatitis and purpura fulminans. (26955218)
2016
44
Evaluation of the effectiveness of treatment with prednisone and azathioprine of autoimmune hepatitis in children. (27110306)
2016
45
Prevalence and Risk Factors of Diabetes Mellitus in Patients with Autoimmune Hepatitis. (27086799)
2016
46
Difference in clinical presentation, immunology profile and treatment response of type 1 autoimmune hepatitis between United Kingdom and Singapore patients. (27101826)
2016
47
The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development. (27974250)
2016
48
Soluble programmed death-1 levels are associated with disease activity and treatment response in patients with autoimmune hepatitis. (27604386)
2016
49
Real-time shear wave elastrography and APRI index for evaluating autoimmune hepatitis fibrosis. (28078847)
2016
50
Over-the-counter Drug Induced Autoimmune Hepatitis. (27181535)
2016

Variations for Autoimmune Hepatitis

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Expression for genes affiliated with Autoimmune Hepatitis

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Search GEO for disease gene expression data for Autoimmune Hepatitis.

Pathways for genes affiliated with Autoimmune Hepatitis

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Pathways related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

(show all 11)
idSuper pathwaysScoreTop Affiliating Genes
19.5CD40LG, CTLA4, PDCD1
29.5CD40LG, CTLA4, PDCD1
39.3CTLA4, HLA-DQB1, HLA-DRB1
49.3CTLA4, HLA-DQB1, HLA-DRB1
5
Show member pathways
9.2HLA-DQB1, HLA-DRB1, PDCD1
6
Show member pathways
9.0CD40LG, CTLA4, HLA-DQB1, HLA-DRB1
7
Show member pathways
8.9CTLA4, HLA-DQB1, HLA-DRB1, PDCD1
88.7CD40LG, CTLA4, FAS, PDCD1
9
Show member pathways
8.7CD40LG, CTLA4, FAS, PDCD1
108.3CD40LG, CTLA4, HLA-A, HLA-DQB1, HLA-DRB1, PDCD1
11
Show member pathways
7.8CD40LG, CTLA4, FAS, HLA-A, HLA-DQB1, HLA-DRB1

GO Terms for genes affiliated with Autoimmune Hepatitis

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Cellular components related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ER to Golgi transport vesicle membraneGO:001250710.0HLA-A, HLA-DQB1, HLA-DRB1
2MHC class II protein complexGO:00426139.6HLA-DQB1, HLA-DRB1
3integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.6HLA-A, HLA-DQB1, HLA-DRB1
4external side of plasma membraneGO:00098978.9CD40LG, CTLA4, F2, FAS, HLA-DRB1, PDCD1
5extracellular exosomeGO:00700627.3F2, FAS, FTCD, GGT1, GPT, HLA-A

Biological processes related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1alkaloid metabolic processGO:000982010.5CYP1A2, CYP2D6
2drug catabolic processGO:004273710.5CYP1A2, CYP2D6
3heterocycle metabolic processGO:004648310.5CYP1A2, CYP2D6
4monoterpenoid metabolic processGO:001609810.4CYP1A2, CYP2D6
5oxidative demethylationGO:007098910.4CYP1A2, CYP2D6
6antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:000250410.3HLA-DQB1, HLA-DRB1
7humoral immune response mediated by circulating immunoglobulinGO:000245510.3HLA-DQB1, HLA-DRB1
8immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.2HLA-DQB1, HLA-DRB1
9negative thymic T cell selectionGO:004506010.0AIRE, FAS
10hepatocyte apoptotic processGO:009728410.0FAS, KRT8
11antigen processing and presentationGO:00198829.9HLA-A, HLA-DQB1, HLA-DRB1
12interferon-gamma-mediated signaling pathwayGO:00603339.8HLA-A, HLA-DQB1, HLA-DRB1
13xenobiotic metabolic processGO:00068059.3CYP1A2, CYP2D6, GGT1
14T cell costimulationGO:00312959.1CD40LG, CTLA4, HLA-DQB1, HLA-DRB1, PDCD1
15immune responseGO:00069558.2AIRE, CD40LG, CTLA4, FAS, HLA-A, HLA-DQB1

Molecular functions related to Autoimmune Hepatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenGO:001671210.2CYP1A2, CYP2D6
2MHC class II receptor activityGO:003239510.0HLA-DQB1, HLA-DRB1
3peptide antigen bindingGO:00426059.2HLA-A, HLA-DQB1, HLA-DRB1

Sources for Autoimmune Hepatitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet