AIED
MCID: ATM021
MIFTS: 22

Autoimmune Inner Ear Disease (AIED) malady

Ear diseases category

Summaries for Autoimmune Inner Ear Disease

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Autoimmune inner ear disease is a suspected autoimmune disease characterized by rapidly progressive... more...

MalaCards: Autoimmune Inner Ear Disease, also known as AIED, is related to coronary artery disease and type 2 diabetes mellitus. An important gene associated with Autoimmune Inner Ear Disease is COCH (cochlin), and among its related pathways are Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway and Allograft rejection. The compounds delta-12-pgj2 and geranylgeranylacetone have been mentioned in the context of this disorder.

Aliases & Classifications for Autoimmune Inner Ear Disease

About this section
Sources:
42NIH Rare Diseases
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

autoimmune inner ear disease 42
aied 42


Related Diseases for Autoimmune Inner Ear Disease

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Autoimmune Inner Ear Disease:



Diseases related to autoimmune inner ear disease

Clinical Features for Autoimmune Inner Ear Disease

About this section

Drugs & Therapeutics for Autoimmune Inner Ear Disease

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Autoimmune Inner Ear Disease

Drug clinical trials:

Search ClinicalTrials for Autoimmune Inner Ear Disease

Search NIH Clinical Center for Autoimmune Inner Ear Disease

Search CenterWatch for Autoimmune Inner Ear Disease

Genetic Tests for Autoimmune Inner Ear Disease

About this section

Anatomical Context for Autoimmune Inner Ear Disease

About this section

Animal Models for Autoimmune Inner Ear Disease or affiliated genes

About this section

Publications for Autoimmune Inner Ear Disease

About this section

Genetic Variations for Autoimmune Inner Ear Disease

About this section

Expression for genes affiliated with Autoimmune Inner Ear Disease

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Autoimmune Inner Ear Disease

Search GEO for disease gene expression data for Autoimmune Inner Ear Disease.

Pathways for genes affiliated with Autoimmune Inner Ear Disease

About this section
Sources:
12EMD Millipore, 37NCBI BioSystems Database, 29KEGG, 53Reactome, 51QIAGEN
See all sources

Pathways related to Autoimmune Inner Ear Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1HSPA4, HSPA8
2
Hide members
9.1HSPA4, HSPA8
3
Regulation of degradation of wt-CFTR
9.1HSPA4, HSPA8
4
Hide members
9.1HSPA8, HSPA4
59.1HSPA4, HSPA8
6
CFTR folding and maturation (norm and CF)
9.1HSPA4, HSPA8
79.1HSPA4, HSPA8

Compounds for genes affiliated with Autoimmune Inner Ear Disease

About this section
Sources:
44Novoseek, 59Tocris Bioscience, 11DrugBank, 28IUPHAR, 24HMDB, 49PharmGKB
See all sources

Compounds related to Autoimmune Inner Ear Disease according to GeneCards/GeneDecks:

(show all 34)
idCompoundScoreTop Affiliating Genes
1delta-12-pgj2449.5HSPA4, HSPA8
2geranylgeranylacetone449.5HSPA4, HSPA8
3cyclopentenone449.5HSPA8, HSPA4
4cdcl2449.5HSPA4, HSPA8
5phenylbutyrate449.5HSPA8, HSPA4
68-oxo-dg449.5HSPA8, HSPA4
7manumycin449.5HSPA4, HSPA8
8radicicol44 59 1111.5HSPA4, HSPA8
917-(allylamino)-17-demethoxygeldanamycin449.5HSPA8, HSPA4
10sodium arsenite449.5HSPA4, HSPA8
113-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide449.5HSPA4, HSPA8
12rotenone449.5HSPA8, HSPA4
13manganese superoxide449.5HSPA4, HSPA8
14salicylic acid44 2810.5HSPA8, HSPA4
15cadmium44 2410.5HSPA4, HSPA8
164-hydroxynonenal44 2410.5HSPA4, HSPA8
17silver449.5HSPA4, HSPA8
18adpribose449.4HSPA8, HSPA4
19geldanamycin44 49 59 1112.4HSPA4, HSPA8
20alpha tocopherol449.4HSPA4, HSPA8
21sodium nitroprusside449.4HSPA4, HSPA8
22mannitol44 1110.4HSPA8, HSPA4
23adriamycin449.4HSPA4, HSPA8
24mg 13244 5910.4HSPA4, HSPA8
25agarose449.4HSPA4, HSPA8
26herbimycin a44 5910.3HSPA8, HSPA4
27quercetin44 59 11 2412.3HSPA4, HSPA8
28curcumin449.3HSPA4, HSPA8
29arsenite44 2410.2HSPA4, HSPA8
30prostaglandin449.2HSPA8, HSPA4
31glycerol44 11 2411.1HSPA4, HSPA8
32butyrate449.1HSPA4, HSPA8
33polyacrylamide449.0HSPA4, HSPA8
34n acetylcysteine448.8HSPA4, HSPA8

GO Terms for genes affiliated with Autoimmune Inner Ear Disease

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Autoimmune Inner Ear Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to unfolded proteinGO:0069869.1HSPA4, HSPA8

Products for genes affiliated with Autoimmune Inner Ear Disease

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Autoimmune Inner Ear Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet