AIED
MCID: ATM021
MIFTS: 34

Autoimmune Inner Ear Disease (AIED) malady

Rare diseases, Ear diseases categories
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Summaries for Autoimmune Inner Ear Disease

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Wikipedia:65 Autoimmune inner ear disease is a suspected autoimmune disease characterized by rapidly progressive... more...

MalaCards based summary: Autoimmune Inner Ear Disease, also known as AIED, is related to influenza and type 2 diabetes mellitus. An important gene associated with Autoimmune Inner Ear Disease is COCH (cochlin), and among its related pathways are Parkin-Ubiquitin Proteasomal System pathway and Allograft rejection. The compounds delta-12-pgj2 and geranylgeranylacetone have been mentioned in the context of this disorder. Affiliated tissues include lung and testes.

Aliases & Classifications for Autoimmune Inner Ear Disease

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Autoimmune Inner Ear Disease, Aliases & Descriptions:

Name: Autoimmune Inner Ear Disease 42
Aied 42 62
 
Autoimmune Inner Ear Diseases 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Ear diseases


Related Diseases for Autoimmune Inner Ear Disease

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Graphical network of the top 20 diseases related to Autoimmune Inner Ear Disease:



Diseases related to autoimmune inner ear disease

Symptoms for Autoimmune Inner Ear Disease

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Drugs & Therapeutics for Autoimmune Inner Ear Disease

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Drug clinical trials:

Search ClinicalTrials for Autoimmune Inner Ear Disease

Search NIH Clinical Center for Autoimmune Inner Ear Disease

Genetic Tests for Autoimmune Inner Ear Disease

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Anatomical Context for Autoimmune Inner Ear Disease

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MalaCards organs/tissues related to Autoimmune Inner Ear Disease:

32
Lung, Testes

Animal Models for Autoimmune Inner Ear Disease or affiliated genes

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Publications for Autoimmune Inner Ear Disease

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Articles related to Autoimmune Inner Ear Disease:

(show top 50)    (show all 60)
idTitleAuthorsYear
1
Early efficacy trial of anakinra in corticosteroid-resistant autoimmune inner ear disease. (25133431)
2014
2
An open label study to evaluate the safety and efficacy of intratympanic golimumab therapy in patients with autoimmune inner ear disease. (25203561)
2014
3
Cochlin in autoimmune inner ear disease: Is the search for an inner ear autoantigen over? (25199741)
2014
4
IL-1I^ inhibition in autoimmune inner ear disease: can you hear me now? (25133418)
2014
5
Innate immune recognition of molds and homology to the inner ear protein, cochlin, in patients with autoimmune inner ear disease. (23912888)
2013
6
Autoimmune inner ear disease: a retrospective review of forty-seven patients. (23817208)
2013
7
Autoimmune inner ear disease preliminary case report: audiometric findings following steroid treatments. (23800807)
2013
8
Infliximab for autoimmune inner ear disease: case report and literature review. (24125068)
2013
9
Cogan's syndrome: an autoimmune inner ear disease. (22846458)
2013
10
Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach. (20523038)
2011
11
Cochlear implantation in patients with autoimmune inner ear disease including cogan syndrome: a comparison with age- and sex-matched controls. (21082747)
2010
12
Safety of high-dose corticosteroids for the treatment of autoimmune inner ear disease. (19395984)
2009
13
Induction of tolerance by oral administration of beta-tubulin in an animal model of autoimmune inner ear disease. (19365153)
2009
14
Immunosuppressive therapy for autoimmune inner ear disease. (19885385)
2009
15
The diagnosis of autoimmune inner ear disease: evidence and critical pitfalls. (18777037)
2009
16
Autoimmune inner ear disease: clinical and laboratory findings and treatment outcome. (19128599)
2008
17
Recurrent autoimmune inner ear disease (AIED) and polyarteritis nodosa in a patient with large cell lung carcinoma. (16552463)
2007
18
Etanercept treatment for autoimmune inner ear disease: results of a pilot placebo-controlled study. (16151336)
2005
19
Autoimmune inner ear disease. (15377956)
2004
20
Expression of heat shock protein 70 in the cochlea in experimental autoimmune inner ear disease. (11913688)
2002
21
Autoimmune inner ear disease: diagnostic and advanced treatments. (12528256)
2002
22
Clinical and experimental studies of autoimmune inner ear disease. (12211349)
2002
23
Relationship between three inner ear antigens with different molecular weights and autoimmune inner ear disease. (11876599)
2002
24
COCH5B2 is a target antigen of anti-inner ear antibodies in autoimmune inner ear diseases. (11568667)
2001
25
Autoimmune inner ear disease: steroid and cytotoxic drug therapy. (11816893)
2001
26
Identification of beta-actin as a candidate autoantigen in autoimmune inner ear disease. (11122295)
2000
27
Sudden hearing loss and autoimmune inner ear disease. (10976497)
2000
28
Experimental autoimmune inner ear disease: an electrocochleographic and histophysiologic study. (10823474)
2000
29
The role of heat shock protein 70 and its autoantibody in experimental autoimmune inner ear disease]. (12768679)
2000
30
Autoimmune inner ear disease. (11123055)
2000
31
Utility of laboratory testing in autoimmune inner ear disease. (10569401)
1999
32
Sulfoglucuronosyl glycolipids as putative antigens for autoimmune inner ear disease. (9628451)
1998
33
Plasmapheresis in autoimmune inner ear disease: long-term follow-up. (9303152)
1997
34
You're the flight surgeon: autoimmune inner ear disease. (9441590)
1997
35
Autoimmune inner ear disease--a real entity? (9316775)
1997
36
Guinea pig inner ear antigens: extraction and application to the study of human autoimmune inner ear disease. (8583855)
1996
37
Myelin protein Po as a potential autoantigen in autoimmune inner ear disease. (9002556)
1996
38
Autoimmune inner ear disease. (8649900)
1996
39
An observation on otoacoustic emission and ultrastructure of cochlea in experimental autoimmune inner ear disease. (9206068)
1996
40
The MRL-lpr/lpr mouse: a potential model of autoimmune inner ear disease. (8475729)
1993
41
Azathioprine in combination with steroids in the treatment of autoimmune inner-ear disease. (8112477)
1993
42
Biological and clinical aspects of autoimmune inner ear disease. (1509781)
1992
43
Autoimmune inner ear disease: fact or fantasy? (1927721)
1991
44
Autoimmune inner ear disease and ulcerative colitis. (2026952)
1991
45
Autoimmune inner ear disease: a review of basic mechanisms and clinical correlates. (1870168)
1991
46
Autoimmune inner ear disease: results of therapy. (1927720)
1991
47
Theoretical and practical implications for plasmapheresis in autoimmune inner ear disease. (2811552)
1989
48
Effect of anti-inflammatory drugs on collagen-induced autoimmune inner ear disease. (3281543)
1988
49
Practical versus theoretical management of autoimmune inner ear disease. (6374341)
1984
50
Antibody activity in perilymph from rats with type II collagen-induced autoimmune inner ear disease. (6435494)
1984

Variations for Autoimmune Inner Ear Disease

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Expression for genes affiliated with Autoimmune Inner Ear Disease

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Expression patterns in normal tissues for genes affiliated with Autoimmune Inner Ear Disease

Search GEO for disease gene expression data for Autoimmune Inner Ear Disease.

Pathways for genes affiliated with Autoimmune Inner Ear Disease

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Compounds for genes affiliated with Autoimmune Inner Ear Disease

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Compounds related to Autoimmune Inner Ear Disease according to GeneCards/GeneDecks:

(show all 50)
idCompoundScoreTop Affiliating Genes
1delta-12-pgj2449.6HSPA8, HSPA4
2geranylgeranylacetone449.6HSPA8, HSPA4
3cyclopentenone449.6HSPA8, HSPA4
4cdcl2449.6HSPA4, HSPA8
58-oxo-dg449.6HSPA4, HSPA8
6phenylbutyrate449.6HSPA4, HSPA8
7manumycin449.6HSPA8, HSPA4
8radicicol44 61 1111.6HSPA4, HSPA8
917-(allylamino)-17-demethoxygeldanamycin449.6HSPA4, HSPA8
10sodium arsenite449.6HSPA4, HSPA8
113-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide449.6HSPA8, HSPA4
12rotenone449.6HSPA8, HSPA4
13manganese superoxide449.6HSPA8, HSPA4
14salicylic acid44 2810.5HSPA8, HSPA4
15cadmium44 2410.5HSPA8, HSPA4
16silver449.5HSPA8, HSPA4
174-hydroxynonenal44 2410.5HSPA8, HSPA4
18adpribose449.5HSPA8, HSPA4
19geldanamycin44 50 61 1112.5HSPA8, HSPA4
20alpha tocopherol449.5HSPA4, HSPA8
21sodium nitroprusside449.5HSPA4, HSPA8
22mannitol44 1110.5HSPA4, HSPA8
23adriamycin449.5HSPA4, HSPA8
24mg 13244 6110.5HSPA4, HSPA8
25agarose449.5HSPA4, HSPA8
26herbimycin a44 6110.5HSPA8, HSPA4
27quercetin44 61 24 1112.5HSPA4, HSPA8
28curcumin449.5HSPA4, HSPA8
29arsenite44 2410.5HSPA8, HSPA4
30prostaglandin449.5HSPA4, HSPA8
31glycerol44 24 1111.5HSPA8, HSPA4
32polyacrylamide449.5HSPA4, HSPA8
33n acetylcysteine449.5HSPA8, HSPA4
34butyrate449.4HSPA4, HSPA8
35methionine449.4HSPA4, HSPA8
36nmda44 2810.4HSPA4, HSPA8
37acetylcholine44 50 28 24 1113.4HSPA4, HSPA8
38doxorubicin44 50 1111.4HSPA4, HSPA8
39potassium44 24 1111.4HSPA4, HSPA8
40paraffin449.4HSPA4, HSPA8
41glutamine449.4HSPA8, HSPA4
42iron44 2410.3HSPA8, HSPA4
43hydrogen44 2410.3HSPA8, HSPA4
44fatty acid449.3HSPA8, HSPA4
45lactate449.2HSPA8, HSPA4
46dopamine44 28 24 1112.2HSPA8, HSPA4
47superoxide44 2410.1HSPA8, HSPA4
48heparin44 28 24 1112.1HSPA4, HSPA8
49sodium44 2410.0HSPA4, HSPA8
50creatinine448.8HSPA4, HSPA8

GO Terms for genes affiliated with Autoimmune Inner Ear Disease

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Biological processes related to Autoimmune Inner Ear Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to unfolded proteinGO:0069869.1HSPA4, HSPA8

Products for genes affiliated with Autoimmune Inner Ear Disease

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  • Antibodies
  • Proteins
  • Lysates

Sources for Autoimmune Inner Ear Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet