MCID: ATM023
MIFTS: 13

Autoimmune Oophoritis malady

Category: Rare diseases

Aliases & Classifications for Autoimmune Oophoritis

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Aliases & Descriptions for Autoimmune Oophoritis:

Name: Autoimmune Oophoritis 46 66

Classifications:



Summaries for Autoimmune Oophoritis

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NIH Rare Diseases:46 Autoimmune oophoritis is a rare cause of primary ovarian insufficiency (poi). it happens when the body's immune system mistakenly attacks the ovaries causing inflammation, atrophy and fibrosis. these changes stop the ovaries from working normally.  the main symptoms of autoimmune oophorotis are irregular or absent menstrual period (amenorrhea) and symptoms related to ovarian cysts such as abdominal cramping, bloating, nausea and vomiting. autoimmune oophoritis may occur as part of autoimmune polyglandular syndrome type i and type ii but has also been associated with lupus, pernicious anemia, myasthenia gravis and other autoimmune conditions. the underlying cause of autoimmune oophoritis is unknown. diagnosis involves a special blood test which looks for anti-steroid or anti-ovarian antibodies, a pelvic ultrasound to look for enlarged cystic ovaries and tests to rule out other possible causes of poi. management of autoimmune oophoritis involves emotional support, possible estrogen replacement therapy and management of other autoimmune conditions. last updated: 6/6/2016

MalaCards based summary: Autoimmune Oophoritis is related to premature ovarian failure and myasthenia gravis. Affiliated tissues include ovary, testes and t cells.

Related Diseases for Autoimmune Oophoritis

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Diseases related to Autoimmune Oophoritis via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1premature ovarian failure10.0
2myasthenia gravis9.9
3premature menopause9.9
4gastritis9.9
5infertility9.9

Graphical network of diseases related to Autoimmune Oophoritis:



Diseases related to autoimmune oophoritis

Symptoms for Autoimmune Oophoritis

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Drugs & Therapeutics for Autoimmune Oophoritis

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Drugs for Autoimmune Oophoritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisone131853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
2glucocorticoids4756

Interventional clinical trials:

idNameStatusNCT IDPhase
1Steroid Therapy in Autoimmune Premature Ovarian FailureCompletedNCT00001306

Search NIH Clinical Center for Autoimmune Oophoritis

Genetic Tests for Autoimmune Oophoritis

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Anatomical Context for Autoimmune Oophoritis

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MalaCards organs/tissues related to Autoimmune Oophoritis:

34
Ovary, Testes, T cells

Animal Models for Autoimmune Oophoritis or affiliated genes

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Publications for Autoimmune Oophoritis

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Articles related to Autoimmune Oophoritis:

(show all 38)
idTitleAuthorsYear
1
Autoimmune oophoritis: A rarely encountered ovarian lesion. (25885148)
2015
2
Autoimmune oophoritis with multiple molecular targets mitigated by transgenic expression of mater. (21447630)
2011
3
Resolution of autoimmune oophoritis after thymectomy in a myasthenia gravis patient. (22155465)
2011
4
High serum inhibin concentration discriminates autoimmune oophoritis from other forms of primary ovarian insufficiency. (18211971)
2008
5
Autoimmune oophoritis in the adolescent. (18574216)
2008
6
Local lymphocytic and epithelial activation in a case of autoimmune oophoritis. (18054927)
2008
7
Effect of alpha-melanotropin hormone on serum levels of luteinizing hormone and progesterone in experimental rat autoimmune oophoritis. (16716456)
2006
8
Selective theca cell dysfunction in autoimmune oophoritis results in multifollicular development, decreased estradiol, and elevated inhibin B levels. (15705922)
2005
9
Autoimmune oophoritis as a mechanism of follicular dysfunction in women with 46,XX spontaneous premature ovarian failure. (16213850)
2005
10
Effects of alpha-MSH on progesterone and nitric oxide release by cultured ovarian granulosa cells in experimental rat autoimmune oophoritis. (12222744)
2002
11
Post-thymectomy murine experimental autoimmune oophoritis is associated with reduced natural killer cell activity. (9352028)
1997
12
Murine postthymectomy autoimmune oophoritis develops in association with a persistent neonatal-like Th2 response. (9175911)
1997
13
ZP3 peptide vaccine that induces antibody and reversible infertility without autoimmune oophoritis. (8962644)
1996
14
Susceptibility to murine experimental autoimmune oophoritis is associated with genes outside the major histocompatibility complex (MHC). (8862255)
1996
15
Altered target organ. A mechanism of postrecovery resistance to murine autoimmune oophoritis. (7561067)
1995
16
Murine experimental autoimmune oophoritis develops independently of gonadotropin stimulation and is primarily localized in the stroma and theca. (8526990)
1995
17
Anamnestic development of lymphocytic infiltration in murine experimental autoimmune oophoritis is primarily localized in the stroma and theca. (8526989)
1995
18
Autoimmune oophoritis. An incidental finding. (8351251)
1993
19
Interspecies-specific ovarian autoantigens involved in neonatal thymectomy-induced murine autoimmune oophoritis. (7691072)
1993
20
Eosinophilic perifolliculitis: a variant of autoimmune oophoritis? (8253554)
1993
21
Autoimmune oophoritis--a case report. (1285930)
1992
22
Experimental autoimmune oophoritis. II. Both lymphoid cells and antibodies are successful in adoptive transfer. (1777554)
1991
23
Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. (1717580)
1991
24
Autoimmune oophoritis associated with polycystic ovaries. (1916689)
1991
25
Plasma protein and hormone profiles associated with autoimmune oophoritis and ovarian tumorigenesis in neonatally thymectomized mice. (2129762)
1990
26
Neonatal thymectomy affects follicle populations before the onset of autoimmune oophoritis in B6A mice. (2182841)
1990
27
Cystic ovarian enlargement resulting from autoimmune oophoritis. (2761940)
1989
28
Experimental autoimmune oophoritis. I. Inhibition of fertility in rats isoimmunized with homogenates of ovary. (2818819)
1989
29
Acute oocyte loss in experimental autoimmune oophoritis as a possible model of premature ovarian failure. (3337168)
1988
30
Premature menopause associated with autoimmune oophoritis. Case report. (3390409)
1988
31
Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. Autoantibodies. (3826296)
1987
32
Persistent progesterone production associated with autoimmune oophoritis. A case report. (3585875)
1987
33
Lymphocyte dysfunction in autoimmune oophoritis. Resumption of menses with corticosteroids. (3740091)
1986
34
Autoimmune oophoritis. (6691297)
1984
35
Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer. (6983557)
1982
36
Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. (6983558)
1982
37
Autoimmune oophoritis in thymectomized mice: detection of circulating antibodies against oocytes. (6998618)
1980
38
Autoimmune oophoritis in thymectomized mice: T cell requirement in adoptive cell transfer. (6970639)
1980

Variations for Autoimmune Oophoritis

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Expression for genes affiliated with Autoimmune Oophoritis

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Search GEO for disease gene expression data for Autoimmune Oophoritis.

Pathways for genes affiliated with Autoimmune Oophoritis

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GO Terms for genes affiliated with Autoimmune Oophoritis

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Sources for Autoimmune Oophoritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet