MCID: ATM019
MIFTS: 43

Autoimmune Polyendocrine Syndrome malady

Categories: Genetic diseases, Endocrine diseases, Immune diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Autoimmune Polyendocrine Syndrome

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Aliases & Descriptions for Autoimmune Polyendocrine Syndrome:

Name: Autoimmune Polyendocrine Syndrome 11 13
Polyendocrinopathies, Autoimmune 37 66
Autoimmune Polyglandular Failure 11
 
Polyendocrinopathies Autoimmune 48
Autoimmune Polyendocrinopathy 11
Lloyd's Syndrome 11

Classifications:



External Ids:

Disease Ontology11 DOID:14040
ICD1028 E31.0
MeSH37 D016884
NCIt43 C84576

Summaries for Autoimmune Polyendocrine Syndrome

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Disease Ontology:11 An autoimmune disease of endocrine system characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs.

MalaCards based summary: Autoimmune Polyendocrine Syndrome, also known as polyendocrinopathies, autoimmune, is related to autoimmune polyendocrine syndrome, type ii and autoimmune polyendocrine syndrome type 1. An important gene associated with Autoimmune Polyendocrine Syndrome is AIRE (Autoimmune Regulator), and among its related pathways are Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics and serotonin and melatonin biosynthesis. Affiliated tissues include thyroid, pituitary and testis, and related mouse phenotypes are respiratory system and digestive/alimentary.

Wikipedia:69 In medicine, autoimmune polyendocrine syndromes, also called polyglandular autoimmune syndrome (PGAS),... more...

Related Diseases for Autoimmune Polyendocrine Syndrome

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Diseases in the Autoimmune Polyendocrine Syndrome family:

Autoimmune Polyendocrine Syndrome, Type Ii Autoimmune Polyendocrine Syndrome Type 1

Diseases related to Autoimmune Polyendocrine Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrine syndrome, type ii12.5
2autoimmune polyendocrine syndrome type 112.4
3autoimmune polyendocrinopathy syndrome , type i, with or without reversible metaphyseal dysplasia11.7
4autoimmune polyglandular syndrome type 311.2
5autoimmune polyendocrinopathy type 411.2
6autoimmune polyendocrinopathy type 311.2
7autosomal recessive congenital methemoglobinemia10.6AIRE, CYP21A2
8space motion sickness10.6DDC, TH
9dressler's syndrome10.5AIRE, CYP21A2
10atrichia with papular lesions10.5AIRE, CYP21A2
11thyroid cancer, childhood10.5GAD1, TPH1
12repetitive motion disorders10.4DDC, INS
13angelucci's syndrome10.4AIRE, CASR
14immunodysregulation, polyendocrinopathy, and enteropathy, x-linked10.3
15interstitial lung disease10.3TH, TPH1
16glutathionuria10.3GAD2, TPH1
17addison's disease10.3
18gaucher's disease10.3CYP21A2, INS
19hepatitis10.3
20neurilemmoma of the pleura10.2CYP21A2, INS
21dyskinetic cerebral palsy10.2GAD1, GAD2
22maternal uniparental disomy of chromosome 1310.2INS, TH
23measles10.2GAD2, TPH1
24sequeiros sack syndrome10.2GAD1, GAD2
25chancroid10.1AIRE, CYP21A2, INS
26bone fracture10.1GAD1, TH, TPH1
27perry syndrome10.1TH, TPH1
28adrenal carcinoma10.1CYP21A2, INS
29autoimmune hepatitis10.1
30hypoparathyroidism10.1
31cardiomyopathy10.1
32keratoacanthoma10.0CYP21A2, INS
33candidiasis10.0
34chronic mucocutaneous candidiasis10.0
35thyroiditis10.0
36psoriasis10.0
37parkinson disease, late-onset9.9DDC, GAD1, TH, TPH1
38systemic lupus erythematosus9.9
39hepatocellular carcinoma9.9
40hepatitis c virus9.9
41cerebellar ataxia9.9
42acute leukemia9.9
43alopecia9.9
44leukemia9.9
45primary biliary cirrhosis9.9
46cardiac arrest9.9
47down syndrome9.9
48calcinosis9.9
49hepatitis c9.9
50thrombocytosis9.9

Graphical network of the top 20 diseases related to Autoimmune Polyendocrine Syndrome:



Diseases related to autoimmune polyendocrine syndrome

Symptoms for Autoimmune Polyendocrine Syndrome

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Drugs & Therapeutics for Autoimmune Polyendocrine Syndrome

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Drugs for Autoimmune Polyendocrine Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MiconazolePhase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
Amphotericin BPhase 21171397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
CID1972
 
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b

Interventional clinical trials:

idNameStatusNCT IDPhase
1CAMB/MAT2203 in Patients With Mucocutaneous CandidiasisRecruitingNCT02629419Phase 2
2Studies of Disorders With Increased Susceptibility to Fungal InfectionsRecruitingNCT01222741
3Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down SyndromeNot yet recruitingNCT02421276

Search NIH Clinical Center for Autoimmune Polyendocrine Syndrome


Cochrane evidence based reviews: polyendocrinopathies, autoimmune

Genetic Tests for Autoimmune Polyendocrine Syndrome

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Anatomical Context for Autoimmune Polyendocrine Syndrome

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MalaCards organs/tissues related to Autoimmune Polyendocrine Syndrome:

34
Thyroid, Pituitary, Testis, Brain

Animal Models for Autoimmune Polyendocrine Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Polyendocrine Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4AIRE, GAD1, GAD2, IL17A, TH, TPH1
2MP:00053818.0AIRE, CASR, GAD1, GAD2, IL17A, INS
3MP:00030127.9AIRE, GAD1, GAD2, IL17A, INS, TH
4MP:00053797.2AIRE, CASR, GAD1, GAD2, INS, TDRD6
5MP:00053866.8AIRE, CASR, DDC, GAD1, GAD2, INS
6MP:00053766.7AIRE, CASR, DDC, GAD1, GAD2, IL17A
7MP:00053786.6AIRE, CASR, DDC, GAD1, GAD2, IL17A

Publications for Autoimmune Polyendocrine Syndrome

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Articles related to Autoimmune Polyendocrine Syndrome:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Identification of autoimmune polyendocrine syndrome type 1 in patients with isolated hypoparathyroidism. (27219120)
2016
2
Serological proteome analysis reveals new specific biases in the IgM and IgG autoantibody repertoires in autoimmune polyendocrine syndrome type 1. (26312540)
2015
3
Autoimmune polyendocrine syndrome 3 onset with severe ketoacidosis in a 74-year-old woman. (25821607)
2015
4
Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens. (25475693)
2015
5
Fulminant hepatic failure in autoimmune polyendocrine syndrome type-1. (26181530)
2015
6
Psoriasis vulgaris and autoimmune polyendocrine syndrome type I: a case report. (24825086)
2014
7
A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. (24792136)
2014
8
Successful management of insulin allergy and autoimmune polyendocrine syndrome type 4 with desensitization therapy and glucocorticoid treatment: a case report and review of the literature. (25548690)
2014
9
Shock: A possible presenting manifestation of autoimmune polyendocrine syndrome type II. (24914264)
2014
10
Cutaneous vasculitis in patients with autoimmune polyendocrine syndrome type 1: report of a case and brief review of the literature. (25361846)
2014
11
Autoimmune retinopathy in a patient with autoimmune polyendocrine syndrome type I. (23697860)
2013
12
Autoimmune polyendocrine syndrome: a case-based review. (23641891)
2013
13
Autoimmunity and cystatin SA1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type 1. (23122533)
2013
14
Reversible cardiomyopathy associated with autoimmune polyendocrine syndrome type II. (23648718)
2013
15
Hashimoto's thyroiditis concomitant with sequential autoimmune hepatitis, chorea and polyserositis: a new entity of autoimmune polyendocrine syndrome? (23318858)
2013
16
Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients. (22344197)
2012
17
Autoimmune polyendocrine syndrome type 1: case report and review of literature. (22460196)
2012
18
Peripartum cardiomyopathy in type II autoimmune polyendocrine syndrome. (19303650)
2011
19
Insulin-dependent diabetes mellitus associated with presumed autoimmune polyendocrine syndrome in a mare. (22043070)
2011
20
Measuring autoantibodies against IL-17F and IL-22 in autoimmune polyendocrine syndrome type I by radioligand binding assay using fusion proteins. (21535082)
2011
21
Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model. (21182094)
2011
22
TSGA10 - A target for autoantibodies in autoimmune polyendocrine syndrome type 1 and systemic lupus erythematosus. (21198756)
2011
23
Autoimmune polyendocrine syndrome type 1 in north-western France: AIRE gene mutation specificities and severe forms needing immunosuppressive therapies. (20453472)
2010
24
Primary pulmonary arterial hypertension and autoimmune polyendocrine syndrome in a pediatric patient. (20411253)
2010
25
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. (20123958)
2010
26
Predictive role of the immunostaining pattern of immunofluorescence and the titers of antipituitary antibodies at presentation for the occurrence of autoimmune hypopituitarism in patients with autoimmune polyendocrine syndromes over a five-year follow-up. (20501686)
2010
27
Autoimmune polyendocrine syndrome type 1 (APS-1) as a model for understanding autoimmune polyendocrine syndrome type 2 (APS-2). (19382992)
2009
28
Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. (19251657)
2009
29
Activating autoantibodies against the calcium-sensing receptor detected in two patients with autoimmune polyendocrine syndrome type 1. (19837919)
2009
30
Apeced syndrome or autoimmune polyendocrine syndrome Type 1]. (18296018)
2008
31
Testis-expressed protein TSGA10 an auto-antigen in autoimmune polyendocrine syndrome type I. (18000009)
2008
32
Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. (18708298)
2008
33
Autoimmune polyendocrine syndrome with atrial septal defect. (18277128)
2008
34
Autoantibodies against type I interferons as an additional diagnostic criterion for autoimmune polyendocrine syndrome type I. (18728167)
2008
35
Autoimmune polyendocrine syndrome type I in Slovakia: relevance of screening patients with autoimmune Addison's disease. (18426830)
2008
36
Absence of autoantibodies connected to autoimmune polyendocrine syndrome type I and II and Addison's disease in girls and women with Turner syndrome. (18088406)
2007
37
The calcium-sensing receptor is a target of autoantibodies in patients with autoimmune polyendocrine syndrome type 1. (17374709)
2007
38
Median eminence dopaminergic nerve terminals: a novel target in autoimmune polyendocrine syndrome? (15855266)
2005
39
Hypoparathyroidism and autoimmune polyendocrine syndromes. (15342816)
2004
40
Autoantibodies in autoimmune polyendocrine syndrome type II. (12092456)
2002
41
Autoimmune polyendocrine syndrome (APS)]. (12564102)
2002
42
Autoimmune polyendocrine syndrome type 1 (APS I) in Norway. (11207636)
2001
43
The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I. (11423552)
2001
44
Pteridin-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type I. (10946908)
2000
45
Autoantibodies against recombinant human steroidogenic enzymes 21-hydroxylase, side-chain cleavage and 17alpha-hydroxylase in Addison's disease and autoimmune polyendocrine syndrome type III. (10664529)
2000
46
Antibodies against hair follicles are associated with alopecia totalis in autoimmune polyendocrine syndrome type I. (10594751)
1999
47
Autoantibodies against aromatic L-amino acid decarboxylase in autoimmune polyendocrine syndrome type I. (8989249)
1997
48
Cytochrome P450IA2 and aromatic L-amino acid decarboxylase are hepatic autoantigens in autoimmune polyendocrine syndrome type I. (9276443)
1997
49
Association between antibodies to the MR 67,000 isoform of glutamate decarboxylase (GAD) and type 1 (insulin-dependent) diabetes mellitus with coexisting autoimmune polyendocrine syndrome type II. (7578849)
1994
50
GAD autoantibodies in IDDM, stiff-man syndrome, and autoimmune polyendocrine syndrome type I recognize different epitopes. (7505244)
1994

Variations for Autoimmune Polyendocrine Syndrome

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Copy number variations for Autoimmune Polyendocrine Syndrome from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1159448214260000048129895DeletionAIREAutoimmune polyendocrine syndrome

Expression for genes affiliated with Autoimmune Polyendocrine Syndrome

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Search GEO for disease gene expression data for Autoimmune Polyendocrine Syndrome.

Pathways for genes affiliated with Autoimmune Polyendocrine Syndrome

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Pathways related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.9DDC, TPH1
2
Show member pathways
9.9DDC, TPH1
3
Show member pathways
9.7GAD1, GAD2
4
Show member pathways
9.7GAD1, GAD2
5
Show member pathways
9.7GAD1, GAD2
69.7GAD1, GAD2
79.7GAD1, GAD2
89.7GAD1, GAD2
99.7DDC, TH
109.7DDC, TH
119.7DDC, TH
12
Show member pathways
9.3DDC, TH, TPH1
139.3DDC, TH, TPH1
149.2GAD1, GAD2, TH
15
Show member pathways
8.6DDC, GAD1, GAD2, TH, TPH1
168.6DDC, GAD1, GAD2, TH, TPH1
17
Show member pathways
8.6DDC, GAD1, GAD2, TH, TPH1
18
Show member pathways
8.4GAD1, GAD2, IL17A, INS

GO Terms for genes affiliated with Autoimmune Polyendocrine Syndrome

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Cellular components related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneGO:00612029.7GAD1, GAD2

Biological processes related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1glutamate decarboxylation to succinateGO:000654010.2GAD1, GAD2
2serotonin biosynthetic processGO:004242710.0DDC, TPH1
3indolalkylamine biosynthetic processGO:00462199.9DDC, TPH1
4dopamine biosynthetic processGO:00424169.9DDC, TH
5isoquinoline alkaloid metabolic processGO:00330769.9DDC, TH
6response to immobilization stressGO:00359029.9TH, TPH1
7catecholamine biosynthetic processGO:00424239.8DDC, TH
8response to pyrethroidGO:00466849.8DDC, TH
9cellular response to alkaloidGO:00713129.7DDC, TH
10phytoalexin metabolic processGO:00523149.7DDC, TH
11aminergic neurotransmitter loading into synaptic vesicleGO:00158429.6DDC, TH
12neurotransmitter biosynthetic processGO:00421369.5GAD1, GAD2, TH
13multicellular organism agingGO:00102599.4DDC, TH

Molecular functions related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glutamate decarboxylase activityGO:000435110.2GAD1, GAD2
2glutamate bindingGO:00165959.9GAD1, GAD2
3amino acid bindingGO:00165979.3DDC, TH, TPH1
4pyridoxal phosphate bindingGO:00301709.3DDC, GAD1, GAD2

Sources for Autoimmune Polyendocrine Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet