MCID: ATM019
MIFTS: 47

Autoimmune Polyendocrine Syndrome malady

Categories: Genetic diseases, Endocrine diseases, Immune diseases, Rare diseases, Reproductive diseases, Blood diseases

Aliases & Classifications for Autoimmune Polyendocrine Syndrome

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Aliases & Descriptions for Autoimmune Polyendocrine Syndrome:

Name: Autoimmune Polyendocrine Syndrome 10 12
Polyendocrinopathies, Autoimmune 36 65
Autoimmune Polyglandular Failure 10
 
Polyendocrinopathies Autoimmune 47
Autoimmune Polyendocrinopathy 10
Lloyd's Syndrome 10

Classifications:



External Ids:

Disease Ontology10 DOID:14040
ICD1027 E31.0
MeSH36 D016884
NCIt42 C84576
UMLS65 C0085409

Summaries for Autoimmune Polyendocrine Syndrome

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Disease Ontology:10 An autoimmune disease of endocrine system characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs.

MalaCards based summary: Autoimmune Polyendocrine Syndrome, also known as polyendocrinopathies, autoimmune, is related to autoimmune polyendocrine syndrome type 2 and autoimmune polyendocrine syndrome type 1. An important gene associated with Autoimmune Polyendocrine Syndrome is AIRE (Autoimmune Regulator), and among its related pathways are Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics and Amine-derived hormones. Affiliated tissues include heart, breast and lung, and related mouse phenotypes are no phenotypic analysis and endocrine/exocrine gland.

Wikipedia:68 In medicine, autoimmune polyendocrine syndromes, also called polyglandular autoimmune syndrome (PGAS),... more...

Related Diseases for Autoimmune Polyendocrine Syndrome

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Diseases in the Autoimmune Polyendocrine Syndrome family:

Autoimmune Polyendocrine Syndrome Type 1 Autoimmune Polyendocrine Syndrome Type 2

Diseases related to Autoimmune Polyendocrine Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrine syndrome type 230.7AIRE, CASR, CYP11A1, CYP21A2, DDC, IL17A
2autoimmune polyendocrine syndrome type 112.5
3autoimmune polyendocrinopathy syndrome , type i, with or without reversible metaphyseal dysplasia11.5
4autoimmune polyglandular syndrome type 311.2
5autoimmune polyendocrinopathy type 411.2
6autoimmune polyendocrinopathy type 311.2
7autoimmune polyglandular syndrome type 211.1
8autoimmune polyendocrinopathy type 211.1
9autosomal dominant congenital stationary night blindness10.6AIRE, CYP21A2
10atrichia with papular lesions10.5AIRE, CYP21A2
11children's interstitial lung disease10.5GAD1, TPH1
12primary hyperparathyroidism10.4AIRE, CASR
13spondylocostal dysostosis-anal and genitourinary malformations syndrome10.4CYP11A1, CYP21A2
14breast hemangioma10.3CYP11A1, CYP21A2
15richter's syndrome10.3CYP11A1, CYP21A2
16addison's disease10.3
17renal adenoma10.3CYP11A1, CYP21A2
18bipolar ll disorder10.3GAD2, TPH1
19hepatitis10.3
20neuroblastoma 410.2GAD1, GAD2
21tinea profunda10.2GAD1, GAD2
22artemis deficiency10.2AIRE, GAD2
23linear and whorled nevoid hypermelanosis10.2GAD1, GAD2
24diplegia of upper limb10.2GAD2, TPH1
25neonatal diabetes mellitus10.1GAD1, GAD2
26bone cancer10.1GAD1, GAD2
27cutaneous lupus erythematosus10.1AIRE, FOXP3
28autoimmune hepatitis10.1
29hypoparathyroidism10.1
30cardiomyopathy10.1
31orbital granuloma10.1AIRE, CYP11A1, CYP21A2
32vernal conjunctivitis10.1AIRE, IL17A
33ethmoid sinus inverted papilloma10.1CYP11A1, CYP21A2
34candidiasis10.0
35chronic mucocutaneous candidiasis10.0
36thyroiditis10.0
37psoriasis10.0
38basal cell carcinoma 710.0CYP11A1, CYP21A2
39penile cancer10.0CYP11A1, CYP21A2
40systemic lupus erythematosus9.9
41hepatocellular carcinoma9.9
42hepatitis c virus9.9
43cerebellar ataxia9.9
44acute leukemia9.9
45alopecia9.9
46leukemia9.9
47primary biliary cirrhosis9.9
48cardiac arrest9.9
49down syndrome9.9
50calcinosis9.9

Graphical network of the top 20 diseases related to Autoimmune Polyendocrine Syndrome:



Diseases related to autoimmune polyendocrine syndrome

Symptoms for Autoimmune Polyendocrine Syndrome

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Drugs & Therapeutics for Autoimmune Polyendocrine Syndrome

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Drugs for Autoimmune Polyendocrine Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Cyclophosphamideapproved, investigationalPhase 2264350-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
2
Miconazoleapproved, investigationalPhase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
3
Amphotericin Bapproved, investigationalPhase 21171397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Cholesteryl Sulfate Complex
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
 
CID1972
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
4Antineoplastic Agents, AlkylatingPhase 23406
5Antirheumatic AgentsPhase 28496
6lenograstimPhase 21134
7Alkylating AgentsPhase 23582
8Immunosuppressive AgentsPhase 210422
9Immunologic FactorsPhase 218483
10AutoantibodiesPhase 2117
11Liposomal amphotericin BPhase 2117
12Antiprotozoal AgentsPhase 21730
13Antifungal AgentsPhase 23015
14Anti-Bacterial AgentsPhase 29140
15Anti-Infective AgentsPhase 217220
16Antiparasitic AgentsPhase 21854

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cyclophosphamide in Treating Young Patients With Severe Autoimmune EnteropathyCompletedNCT00258180Phase 2
2CAMB/MAT2203 in Patients With Mucocutaneous CandidiasisRecruitingNCT02629419Phase 2
3Studies of Disorders With Increased Susceptibility to Fungal InfectionsRecruitingNCT01222741
4Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down SyndromeNot yet recruitingNCT02421276

Search NIH Clinical Center for Autoimmune Polyendocrine Syndrome


Cochrane evidence based reviews: polyendocrinopathies, autoimmune

Genetic Tests for Autoimmune Polyendocrine Syndrome

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Anatomical Context for Autoimmune Polyendocrine Syndrome

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MalaCards organs/tissues related to Autoimmune Polyendocrine Syndrome:

33
Heart, Breast, Lung, Thyroid, Pituitary, Brain, Myeloid

Animal Models for Autoimmune Polyendocrine Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Polyendocrine Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.5AIRE, FOXP3, GAD1, GAD2, IL17A
2MP:00053798.3AIRE, CASR, CYP11A1, FOXP3, GAD1, GAD2
3MP:00053888.1AIRE, FOXP3, GAD1, GAD2, IL17A, TPH1
4MP:00053818.1AIRE, CASR, FOXP3, GAD1, GAD2, IL17A
5MP:00053877.7AIRE, CASR, CYP11A1, DDC, FOXP3, GAD2
6MP:00053867.4AIRE, CASR, CYP11A1, DDC, FOXP3, GAD1
7MP:00107686.9AIRE, CASR, CYP11A1, DDC, FOXP3, GAD1
8MP:00053766.7AIRE, CASR, CYP11A1, DDC, FOXP3, GAD1
9MP:00053786.4AIRE, CASR, CYP11A1, DDC, FOXP3, GAD1

Publications for Autoimmune Polyendocrine Syndrome

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Articles related to Autoimmune Polyendocrine Syndrome:

(show top 50)    (show all 91)
idTitleAuthorsYear
1
Identification of autoimmune polyendocrine syndrome type 1 in patients with isolated hypoparathyroidism. (27219120)
2016
2
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1. (26830021)
2016
3
Serological proteome analysis reveals new specific biases in the IgM and IgG autoantibody repertoires in autoimmune polyendocrine syndrome type 1. (26312540)
2015
4
Autoimmune polyendocrine syndrome 3 onset with severe ketoacidosis in a 74-year-old woman. (25821607)
2015
5
Fulminant hepatic failure in autoimmune polyendocrine syndrome type-1. (26181530)
2015
6
Autoimmune polyendocrine syndrome and thrombocytosis. (26229032)
2015
7
Psoriasis vulgaris and autoimmune polyendocrine syndrome type I: a case report. (24825086)
2014
8
Cutaneous vasculitis in patients with autoimmune polyendocrine syndrome type 1: report of a case and brief review of the literature. (25361846)
2014
9
New splice site acceptor mutation in AIRE gene in autoimmune polyendocrine syndrome type 1. (24988226)
2014
10
A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. (24792136)
2014
11
Hashimoto's thyroiditis concomitant with sequential autoimmune hepatitis, chorea and polyserositis: a new entity of autoimmune polyendocrine syndrome? (23318858)
2013
12
Autoimmune retinopathy in a patient with autoimmune polyendocrine syndrome type I. (23697860)
2013
13
Autoimmune polyendocrine syndrome: a case-based review. (23641891)
2013
14
Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in Sardinian patients. (22344197)
2012
15
Tetany due to hypoparathyroidism as the initial manifestation of autoimmune polyendocrine syndrome type-2: A case report. (23565477)
2012
16
Autoimmune polyendocrine syndrome type 1: case report and review of literature. (22460196)
2012
17
Novel neuronal and endocrine autoantibody targets in Autoimmune Polyendocrine Syndrome type 1. (22506635)
2012
18
Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model. (21182094)
2011
19
TSGA10 - A target for autoantibodies in autoimmune polyendocrine syndrome type 1 and systemic lupus erythematosus. (21198756)
2011
20
Acute cardiac arrest secondary to severe hyperkalemia due to autoimmune polyendocrine syndrome type II. (21161541)
2011
21
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. (20123958)
2010
22
Predictive role of the immunostaining pattern of immunofluorescence and the titers of antipituitary antibodies at presentation for the occurrence of autoimmune hypopituitarism in patients with autoimmune polyendocrine syndromes over a five-year follow-up. (20501686)
2010
23
Autoimmune polyendocrine syndrome type 1 in north-western France: AIRE gene mutation specificities and severe forms needing immunosuppressive therapies. (20453472)
2010
24
Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. (19251657)
2009
25
Activating autoantibodies against the calcium-sensing receptor detected in two patients with autoimmune polyendocrine syndrome type 1. (19837919)
2009
26
Autoimmune polyendocrine syndrome type I in Slovakia: relevance of screening patients with autoimmune Addison's disease. (18426830)
2008
27
Apeced syndrome or autoimmune polyendocrine syndrome Type 1]. (18296018)
2008
28
Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. (18322283)
2008
29
AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. (18200029)
2008
30
Absence of autoantibodies connected to autoimmune polyendocrine syndrome type I and II and Addison's disease in girls and women with Turner syndrome. (18088406)
2007
31
Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. (17215373)
2007
32
Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. (17118990)
2007
33
Genetic dissection of autoimmune polyendocrine syndrome type 2: common origin of a spectrum of phenotypes. (17911431)
2007
34
Autoantibodies linked to autoimmune polyendocrine syndrome type I are prevalent in Down syndrome. (17129978)
2006
35
Median eminence dopaminergic nerve terminals: a novel target in autoimmune polyendocrine syndrome? (15855266)
2005
36
Hypoparathyroidism and autoimmune polyendocrine syndromes. (15342816)
2004
37
Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. (14764761)
2004
38
Mutational analysis of the autoimmune regulator (AIRE) gene in sporadic autoimmune Addison's disease can reveal patients with unidentified autoimmune polyendocrine syndrome type I. (11916620)
2002
39
The genetics of autoimmune polyendocrine syndrome type II. (12092455)
2002
40
Autoimmune polyendocrine syndrome type 1 (APS I) in Norway. (11207636)
2001
41
The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I. (11423552)
2001
42
Autoantibodies against recombinant human steroidogenic enzymes 21-hydroxylase, side-chain cleavage and 17alpha-hydroxylase in Addison's disease and autoimmune polyendocrine syndrome type III. (10664529)
2000
43
Antibodies against hair follicles are associated with alopecia totalis in autoimmune polyendocrine syndrome type I. (10594751)
1999
44
Tryptophan hydroxylase autoantibodies and intestinal disease in autoimmune polyendocrine syndrome type 1. (10470707)
1999
45
Autoantibodies against aromatic L-amino acid decarboxylase in autoimmune polyendocrine syndrome type I. (8989249)
1997
46
Association between antibodies to the MR 67,000 isoform of glutamate decarboxylase (GAD) and type 1 (insulin-dependent) diabetes mellitus with coexisting autoimmune polyendocrine syndrome type II. (7578849)
1994
47
Autoantibodies against a novel 51 kDa islet antigen and glutamate decarboxylase isoforms in autoimmune polyendocrine syndrome type I. (8150232)
1994
48
Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type I and Addison's disease. (8227354)
1993
49
Autoimmune polyendocrine syndrome. Treatment with intravenous immunoglobulins]. (1468197)
1992
50

Variations for Autoimmune Polyendocrine Syndrome

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Expression for genes affiliated with Autoimmune Polyendocrine Syndrome

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Search GEO for disease gene expression data for Autoimmune Polyendocrine Syndrome.

Pathways for genes affiliated with Autoimmune Polyendocrine Syndrome

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Pathways related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

(show all 11)
idSuper pathwaysScoreTop Affiliating Genes
19.8DDC, TPH1
2
Show member pathways
9.8DDC, TPH1
3
Show member pathways
9.8DDC, TPH1
4
Show member pathways
9.4GAD1, GAD2
5
Show member pathways
9.4GAD1, GAD2
69.4GAD1, GAD2
7
Show member pathways
9.4GAD1, GAD2
89.4GAD1, GAD2
9
Show member pathways
8.7DDC, GAD1, GAD2, TPH1
108.6CYP21A2, GAD1, GAD2
11
Show member pathways
8.5FOXP3, GAD1, GAD2, IL17A

GO Terms for genes affiliated with Autoimmune Polyendocrine Syndrome

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Cellular components related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneGO:00612029.4GAD1, GAD2

Biological processes related to Autoimmune Polyendocrine Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1indolalkylamine biosynthetic processGO:00462199.8DDC, TPH1
2serotonin biosynthetic processGO:00424279.5DDC, TPH1
3sterol metabolic processGO:00161259.0CYP11A1, CYP21A2

Sources for Autoimmune Polyendocrine Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet