MCID: ATM001
MIFTS: 21

Autoimmune Polyendocrine Syndrome Type 2 malady

Genetic diseases, Immune diseases, Rare diseases, Reproductive diseases, Endocrine diseases, Blood diseases categories

Aliases & Classifications for Autoimmune Polyendocrine Syndrome Type 2

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Aliases & Descriptions for Autoimmune Polyendocrine Syndrome Type 2:

Name: Autoimmune Polyendocrine Syndrome Type 2 10 12
Autoimmune Syndrome Type Ii, Polyglandular 65
 
Schmidt Syndrome 10


Classifications:



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Disease Ontology10 DOID:0050168

Summaries for Autoimmune Polyendocrine Syndrome Type 2

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Disease Ontology:10 An autoimmune polyendocrine syndrome that is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. it is more heterogeneous and has not been linked to one gene.

MalaCards based summary: Autoimmune Polyendocrine Syndrome Type 2, also known as autoimmune syndrome type ii, polyglandular, is related to autoimmune polyendocrine syndrome and bork stender schmidt syndrome. An important gene associated with Autoimmune Polyendocrine Syndrome Type 2 is AIRE (Autoimmune Regulator). Related mouse phenotypes are reproductive system and growth/size/body.

Related Diseases for Autoimmune Polyendocrine Syndrome Type 2

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Graphical network of the top 20 diseases related to Autoimmune Polyendocrine Syndrome Type 2:



Diseases related to autoimmune polyendocrine syndrome type 2

Symptoms for Autoimmune Polyendocrine Syndrome Type 2

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Drugs & Therapeutics for Autoimmune Polyendocrine Syndrome Type 2

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive AdultsCompletedNCT00820846Phase 2
2Safety of and Immune Response to a DNA HIV Vaccine (pGA2/JS7) Boosted With a Modified Vaccinia HIV Vaccine (MVA/HIV62) in Healthy AdultsCompletedNCT00301184Phase 1
3Safety of an HIV DNA Vaccine Given to HIV Uninfected AdultsCompletedNCT00043511Phase 1
4A Safety and Immunogenicity Study of a Plasmid DNA Prime and MVA Boost Vaccine in HIV-1 Infected Adults on ARTCompletedNCT01378156Phase 1

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Genetic Tests for Autoimmune Polyendocrine Syndrome Type 2

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Anatomical Context for Autoimmune Polyendocrine Syndrome Type 2

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Animal Models for Autoimmune Polyendocrine Syndrome Type 2 or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Polyendocrine Syndrome Type 2:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053897.8AES, AIRE, FMR1, FOXP3
2MP:00053787.6AES, AIRE, FMR1, FOXP3, POMC
3MP:00053797.6AES, AIRE, FMR1, FOXP3, POMC
4MP:00053867.5AES, AIRE, FMR1, FOXP3, POMC

Publications for Autoimmune Polyendocrine Syndrome Type 2

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Articles related to Autoimmune Polyendocrine Syndrome Type 2:

idTitleAuthorsYear
1
Hepatitis C virus infection in a child with autoimmune polyendocrine syndrome type 2: a case report. (22839422)
2012
2
Autoimmune polyendocrine syndrome type 1 (APS-1) as a model for understanding autoimmune polyendocrine syndrome type 2 (APS-2). (19382992)
2009
3
Genetic dissection of autoimmune polyendocrine syndrome type 2: common origin of a spectrum of phenotypes. (17911431)
2007
4
Distinct idiotypes of insulin autoantibody in autoimmune polyendocrine syndrome type 2 and childhood onset type 1 diabetes. (15472233)
2004

Variations for Autoimmune Polyendocrine Syndrome Type 2

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Expression for genes affiliated with Autoimmune Polyendocrine Syndrome Type 2

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Search GEO for disease gene expression data for Autoimmune Polyendocrine Syndrome Type 2.

Pathways for genes affiliated with Autoimmune Polyendocrine Syndrome Type 2

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GO Terms for genes affiliated with Autoimmune Polyendocrine Syndrome Type 2

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Biological processes related to Autoimmune Polyendocrine Syndrome Type 2 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of tumor necrosis factor productionGO:00327209.1FOXP3, POMC

Sources for Autoimmune Polyendocrine Syndrome Type 2

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet