MCID: ATM025
MIFTS: 25

Autoimmune Polyglandular Syndrome Type 2 malady

Category: Rare diseases

Aliases & Classifications for Autoimmune Polyglandular Syndrome Type 2

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Aliases & Descriptions for Autoimmune Polyglandular Syndrome Type 2:

Name: Autoimmune Polyglandular Syndrome Type 2 45
Multiple Endocrine Deficiency Syndrome, Type 2 45
Diabetes Mellitus, Addison's Disease, Myxedema 45
Autoimmune Syndrome Type Ii, Polyglandular 65
Autoimmune Syndrome Type Ii Polyglandular 47
Polyglandular Autoimmune Syndrome, Type 2 45
 
Autoimmune Polyendocrine Syndrome Type 2 45
Polyglandular Deficiency Syndrome Type 2 45
Schmidt's Syndrome 45
Schmidt Syndrome 45
Pga 2 45
Aps2 45

Classifications:



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UMLS65 C0085860

Summaries for Autoimmune Polyglandular Syndrome Type 2

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NIH Rare Diseases:45 Autoimmune polyglandular syndrome type 2 is an autoimmune disorder that affects many hormone-producing (endocrine) glands. this condition is characterized by the presence of addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. affected individuals may also have problems with other endocrine glands. autoimmune polyglandular syndrome type 2 is diagnosed in adulthood, typically around age 30. this condition occurs more often in women than men, and treatment primarily involves hormone replacement therapy. the cause of autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors. last updated: 12/28/2015

MalaCards based summary: Autoimmune Polyglandular Syndrome Type 2, also known as multiple endocrine deficiency syndrome, type 2, is related to autoimmune polyendocrine syndrome type 2 and bork stender schmidt syndrome. An important gene associated with Autoimmune Polyglandular Syndrome Type 2 is GAD2 (Glutamate Decarboxylase 2), and among its related pathways is Alzheimers disease. Affiliated tissues include thyroid, bone and lung.

Related Diseases for Autoimmune Polyglandular Syndrome Type 2

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Graphical network of the top 20 diseases related to Autoimmune Polyglandular Syndrome Type 2:



Diseases related to autoimmune polyglandular syndrome type 2

Symptoms for Autoimmune Polyglandular Syndrome Type 2

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Drugs & Therapeutics for Autoimmune Polyglandular Syndrome Type 2

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Autoimmune Polyglandular Syndrome Type 2

Genetic Tests for Autoimmune Polyglandular Syndrome Type 2

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Anatomical Context for Autoimmune Polyglandular Syndrome Type 2

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MalaCards organs/tissues related to Autoimmune Polyglandular Syndrome Type 2:

33
Thyroid, Bone, Lung, Endothelial, Pituitary, Prostate, Ovary

Animal Models for Autoimmune Polyglandular Syndrome Type 2 or affiliated genes

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MGI Mouse Phenotypes related to Autoimmune Polyglandular Syndrome Type 2:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Autoimmune Polyglandular Syndrome Type 2

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Articles related to Autoimmune Polyglandular Syndrome Type 2:

(show all 24)
idTitleAuthorsYear
1
Isolated cortical vein thrombosis in autoimmune polyglandular syndrome type 2. (26935889)
2016
2
Autoimmune polyglandular syndrome type 2: a rare condition in childhood. (25800482)
2015
3
Hyponatremic rhabdomyolysis in Addison's disease in a child with autoimmune polyglandular syndrome type 2. (26300496)
2015
4
Autoimmune Polyglandular Syndrome Type 2 with Alopecia Universalis and Hypoparathyroidism. (26591178)
2015
5
Addison's disease in a patient with hypothyroidism: autoimmune polyglandular syndrome type 2. (26240101)
2015
6
Autoimmune polyglandular syndrome type 2 manifested as Hashimoto's thyroiditis and adrenocortical insufficiency, in Turner syndrome woman, with onset following introduction of treatment with recombinant human growth hormone. (26071578)
2015
7
Anti-inflammatory effects of bromocriptine in a patient with autoimmune polyglandular syndrome type 2. (24977964)
2014
8
Precocious presentation of autoimmune polyglandular syndrome type 2 associated with an AIRE mutation. (25402387)
2014
9
Autoimmune polyglandular syndrome type 2, alopecia universalis and Crohn's disease. (22677116)
2013
10
Brain imaging in cerebellar ataxia associated with autoimmune polyglandular syndrome type 2. (21091821)
2012
11
You're the flight surgeon: autoimmune polyglandular syndrome type 2. (22873000)
2012
12
Coexistence of autoimmune polyglandular syndrome type 2 and diabetes insipidus in pregnancy. (22033074)
2011
13
Autoimmune polyglandular syndrome type 2 induced by treatment with interferon alpha. (21412133)
2011
14
Autoimmune polyglandular syndrome type 2 shows the same HLA class II pattern as type 1 diabetes. (21388354)
2011
15
Autoimmune polyglandular syndrome type 2: an unusual presentation. (21137658)
2010
16
Autoimmune polyglandular syndrome type 2 with myasthenia gravis crisis. (19901721)
2009
17
From macrocytosis to incomplete autoimmune polyglandular syndrome type 2: a poorly known entity. (18205764)
2008
18
A patient with combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2. (17558682)
2007
19
Autoimmune polyglandular syndrome Type 2: the tip of an iceberg? (15270837)
2004
20
Assessment of adrenocortical function and autoantibodies in a baby born to a mother with autoimmune polyglandular syndrome Type 2. (15505983)
2004
21
Pregnancy in a woman suffering from type 1 diabetes associated with Addison's disease and Hashimoto's thyroiditis (fully developed Autoimmune Polyglandular Syndrome Type 2). (15216452)
2004
22
Autoimmune polyglandular syndrome type 2 and osteoporosis in a 69 years old patient]. (16737004)
2003
23
Type 1 diabetes mellitus masked by primary adrenal insufficiency in a child with autoimmune polyglandular syndrome type 2. (12635986)
2003
24
Coexistence of common variable immunodeficiency and autoimmune polyglandular syndrome type 2. (11393580)
2001

Variations for Autoimmune Polyglandular Syndrome Type 2

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Expression for genes affiliated with Autoimmune Polyglandular Syndrome Type 2

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Search GEO for disease gene expression data for Autoimmune Polyglandular Syndrome Type 2.

Pathways for genes affiliated with Autoimmune Polyglandular Syndrome Type 2

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Pathways related to Autoimmune Polyglandular Syndrome Type 2 according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.1ATP5O, INS

GO Terms for genes affiliated with Autoimmune Polyglandular Syndrome Type 2

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Sources for Autoimmune Polyglandular Syndrome Type 2

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet