MCID: ATM061
MIFTS: 19

Autoimmune Polyglandular Syndrome Type 3 malady

Category: Rare diseases

Aliases & Classifications for Autoimmune Polyglandular Syndrome Type 3

About this section

Aliases & Descriptions for Autoimmune Polyglandular Syndrome Type 3:

Name: Autoimmune Polyglandular Syndrome Type 3 45
Autoimmune Polyendocrine Syndrome Type 3 45 65
Polyglandular Type Iii Autoimmune Syndrome 65
 
Polyglandular Autoimmune Syndrome Type 3 45
Aps3 45
Pas3 45

Classifications:



External Ids:

UMLS65 C1535942, C3266027

Summaries for Autoimmune Polyglandular Syndrome Type 3

About this section
NIH Rare Diseases:45 Autoimmune polyglandular syndrome (aps) type 3 is an autoimmune condition that affects the body's endocrine glands. the syndrome, which typically affects women during middle age, results from failure of the glands to produce their hormones. this condition is characterized by autoimmune thyroiditis along with another organ-specific autoimmune disease. the other autoimmune diseases may include diabetes mellitus, pernicious anemia, vitiligo, alopecia, myasthenia gravis, and sjogren's syndrome. the adrenal cortex (the outer layer of the adrenal gland) is not involved. there are three types of autoimmune polyglandular syndrome type 3:  aps3a - autoimmune thyroiditis with immune-mediated diabetes mellitus (imdm) aps3b - autoimmune thyroiditis with pernicious anemia aps3c - autoimmune thyroiditis with vitiligo and/or alopecia and/or other organ-specific autoimmune disease last updated: 1/15/2013

MalaCards based summary: Autoimmune Polyglandular Syndrome Type 3, also known as autoimmune polyendocrine syndrome type 3, is related to autoimmune polyendocrinopathy type 3 and alopecia. An important gene associated with Autoimmune Polyglandular Syndrome Type 3 is CYP21A2 (Cytochrome P450 Family 21 Subfamily A Member 2). Affiliated tissues include cortex, thyroid and adrenal cortex.

Related Diseases for Autoimmune Polyglandular Syndrome Type 3

About this section

Diseases in the Autoimmune Polyglandular Syndrome Type 2 family:

autoimmune polyglandular syndrome type 3

Diseases related to Autoimmune Polyglandular Syndrome Type 3 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrinopathy type 311.2
2alopecia10.1
3hypothyroidism10.1
4growth hormone deficiency10.1
5alopecia universalis10.0
6myasthenia gravis10.0
7ulcerative colitis10.0
8colitis10.0
9von willebrand's disease10.0
10thyroiditis10.0
11alopecia areata10.0
12schizophrenia10.0
13neuronitis10.0

Graphical network of diseases related to Autoimmune Polyglandular Syndrome Type 3:



Diseases related to autoimmune polyglandular syndrome type 3

Symptoms for Autoimmune Polyglandular Syndrome Type 3

About this section

Drugs & Therapeutics for Autoimmune Polyglandular Syndrome Type 3

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Autoimmune Polyglandular Syndrome Type 3

Genetic Tests for Autoimmune Polyglandular Syndrome Type 3

About this section

Anatomical Context for Autoimmune Polyglandular Syndrome Type 3

About this section

MalaCards organs/tissues related to Autoimmune Polyglandular Syndrome Type 3:

33
Cortex, Thyroid, Adrenal cortex, Adrenal gland, Lung, Breast, Spinal cord

Animal Models for Autoimmune Polyglandular Syndrome Type 3 or affiliated genes

About this section

Publications for Autoimmune Polyglandular Syndrome Type 3

About this section

Articles related to Autoimmune Polyglandular Syndrome Type 3:

(show all 12)
idTitleAuthorsYear
1
Recovery from alopecia areata in a patient with autoimmune polyglandular syndrome type 3. (25759758)
2015
2
Clinical and genetic characteristics of autoimmune polyglandular syndrome type 3 variant in the Japanese population. (22466347)
2012
3
Coexistence of growth hormone deficiency and autoimmune polyglandular syndrome type 3. (22635089)
2012
4
Autoimmune polyglandular syndrome type 3 with anorexia. (23304573)
2012
5
Genetics of the autoimmune polyglandular syndrome type 3 variant. (20578896)
2010
6
Autoimmune polyglandular syndrome Type 3 and growth hormone deficiency. (19968812)
2010
7
Autoimmune polyglandular syndrome type 3 complicated by mineralocorticoid-responsive hyponatremia of the elderly. (21537439)
2010
8
Silent thyroiditis, isolated corticotropin deficiency, and alopecia universalis in a patient with ulcerative colitis and elevated levels of plasma factor VIII: an unusual case of autoimmune polyglandular syndrome type 3. (19289325)
2009
9
Acquired von Willebrand's disease in the course of severe primary hypothyroidism in a patient with autoimmune polyglandular syndrome type 3]. (18335399)
2008
10
Atypical autoimmune polyglandular syndrome type 3 overlapped by chronic HCV infection resulting in carcinogenesis and fatal infection. (18580728)
2008
11
Acquired von Willebrand's syndrome in a patient with severe primary hypothyroidism associated with myasthenia gravis in the course of autoimmune polyglandular syndrome type 3. (17880463)
2007
12
A rare case of autoimmune polyglandular syndrome type 3. (12951278)
2003

Variations for Autoimmune Polyglandular Syndrome Type 3

About this section

Expression for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section
Search GEO for disease gene expression data for Autoimmune Polyglandular Syndrome Type 3.

Pathways for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section

GO Terms for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section

Sources for Autoimmune Polyglandular Syndrome Type 3

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet