MCID: ATM061
MIFTS: 17

Autoimmune Polyglandular Syndrome Type 3 malady

Category: Rare diseases

Aliases & Classifications for Autoimmune Polyglandular Syndrome Type 3

About this section

Aliases & Descriptions for Autoimmune Polyglandular Syndrome Type 3:

Name: Autoimmune Polyglandular Syndrome Type 3 46
Autoimmune Polyendocrine Syndrome Type 3 46 66
Polyglandular Type Iii Autoimmune Syndrome 66
 
Polyglandular Autoimmune Syndrome Type 3 46
Pas3 46
Aps3 46

Classifications:



Summaries for Autoimmune Polyglandular Syndrome Type 3

About this section
NIH Rare Diseases:46 Autoimmune polyglandular syndrome (aps) type 3 is an autoimmune condition that affects the body's endocrine glands. the syndrome, which typically affects women during middle age, results from failure of the glands to produce their hormones. this condition is characterized by autoimmune thyroiditis along with another organ-specific autoimmune disease. the other autoimmune diseases may include diabetes mellitus, pernicious anemia, vitiligo, alopecia, myasthenia gravis, and sjogren's syndrome. the adrenal cortex (the outer layer of the adrenal gland) is not involved. there are three types of autoimmune polyglandular syndrome type 3:  aps3a - autoimmune thyroiditis with immune-mediated diabetes mellitus (imdm) aps3b - autoimmune thyroiditis with pernicious anemia aps3c - autoimmune thyroiditis with vitiligo and/or alopecia and/or other organ-specific autoimmune disease last updated: 1/15/2013

MalaCards based summary: Autoimmune Polyglandular Syndrome Type 3, also known as autoimmune polyendocrine syndrome type 3, is related to autoimmune polyendocrinopathy type 3 and alopecia. An important gene associated with Autoimmune Polyglandular Syndrome Type 3 is CYP21A2 (Cytochrome P450 Family 21 Subfamily A Member 2). Affiliated tissues include thyroid, adrenal cortex and adrenal gland.

Related Diseases for Autoimmune Polyglandular Syndrome Type 3

About this section

Diseases related to Autoimmune Polyglandular Syndrome Type 3 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrinopathy type 311.2
2alopecia10.1
3hypothyroidism10.1
4growth hormone deficiency10.1
5alopecia universalis10.0
6myasthenia gravis10.0
7ulcerative colitis10.0
8colitis10.0
9thyroiditis10.0
10alopecia areata10.0
11schizophrenia10.0
12neuronitis10.0

Graphical network of diseases related to Autoimmune Polyglandular Syndrome Type 3:



Diseases related to autoimmune polyglandular syndrome type 3

Symptoms for Autoimmune Polyglandular Syndrome Type 3

About this section

Drugs & Therapeutics for Autoimmune Polyglandular Syndrome Type 3

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Autoimmune Polyglandular Syndrome Type 3

Genetic Tests for Autoimmune Polyglandular Syndrome Type 3

About this section

Anatomical Context for Autoimmune Polyglandular Syndrome Type 3

About this section

MalaCards organs/tissues related to Autoimmune Polyglandular Syndrome Type 3:

34
Thyroid, Adrenal cortex, Adrenal gland, Cortex

Animal Models for Autoimmune Polyglandular Syndrome Type 3 or affiliated genes

About this section

Publications for Autoimmune Polyglandular Syndrome Type 3

About this section

Articles related to Autoimmune Polyglandular Syndrome Type 3:

(show all 13)
idTitleAuthorsYear
1
Autoimmune polyglandular syndrome type 3 (APS-3) among patients with premature ovarian insufficiency (POI). (27240263)
2016
2
Recovery from alopecia areata in a patient with autoimmune polyglandular syndrome type 3. (25759758)
2015
3
Clinical and genetic characteristics of autoimmune polyglandular syndrome type 3 variant in the Japanese population. (22466347)
2012
4
Coexistence of growth hormone deficiency and autoimmune polyglandular syndrome type 3. (22635089)
2012
5
Autoimmune polyglandular syndrome type 3 with anorexia. (23304573)
2012
6
Autoimmune polyglandular syndrome Type 3 and growth hormone deficiency. (19968812)
2010
7
Autoimmune polyglandular syndrome type 3 complicated by mineralocorticoid-responsive hyponatremia of the elderly. (21537439)
2010
8
Genetics of the autoimmune polyglandular syndrome type 3 variant. (20578896)
2010
9
Silent thyroiditis, isolated corticotropin deficiency, and alopecia universalis in a patient with ulcerative colitis and elevated levels of plasma factor VIII: an unusual case of autoimmune polyglandular syndrome type 3. (19289325)
2009
10
Acquired von Willebrand's disease in the course of severe primary hypothyroidism in a patient with autoimmune polyglandular syndrome type 3]. (18335399)
2008
11
Atypical autoimmune polyglandular syndrome type 3 overlapped by chronic HCV infection resulting in carcinogenesis and fatal infection. (18580728)
2008
12
Acquired von Willebrand's syndrome in a patient with severe primary hypothyroidism associated with myasthenia gravis in the course of autoimmune polyglandular syndrome type 3. (17880463)
2007
13
A rare case of autoimmune polyglandular syndrome type 3. (12951278)
2003

Variations for Autoimmune Polyglandular Syndrome Type 3

About this section

Expression for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section
Search GEO for disease gene expression data for Autoimmune Polyglandular Syndrome Type 3.

Pathways for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section

GO Terms for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

About this section

Sources for Autoimmune Polyglandular Syndrome Type 3

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet