MCID: ATM061
MIFTS: 16

Autoimmune Polyglandular Syndrome Type 3 malady

Category: Rare diseases

Aliases & Classifications for Autoimmune Polyglandular Syndrome Type 3

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Aliases & Descriptions for Autoimmune Polyglandular Syndrome Type 3:

Name: Autoimmune Polyglandular Syndrome Type 3 45
Autoimmune Polyendocrine Syndrome Type 3 45 65
Polyglandular Type Iii Autoimmune Syndrome 65
 
Polyglandular Autoimmune Syndrome Type 3 45
Aps3 45
Pas3 45

Classifications:



External Ids:

UMLS65 C1535942, C3266027

Summaries for Autoimmune Polyglandular Syndrome Type 3

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NIH Rare Diseases:45 Autoimmune polyglandular syndrome (aps) type 3 is an autoimmune condition that affects the body's endocrine glands. the syndrome, which typically affects women during middle age, results from failure of the glands to produce their hormones. this condition is characterized by autoimmune thyroiditis along with another organ-specific autoimmune disease. the other autoimmune diseases may include diabetes mellitus, pernicious anemia, vitiligo, alopecia, myasthenia gravis, and sjogren's syndrome. the adrenal cortex (the outer layer of the adrenal gland) is not involved. there are three types of autoimmune polyglandular syndrome type 3:  aps3a - autoimmune thyroiditis with immune-mediated diabetes mellitus (imdm) aps3b - autoimmune thyroiditis with pernicious anemia aps3c - autoimmune thyroiditis with vitiligo and/or alopecia and/or other organ-specific autoimmune disease last updated: 1/15/2013

MalaCards based summary: Autoimmune Polyglandular Syndrome Type 3, also known as autoimmune polyendocrine syndrome type 3, is related to autoimmune polyendocrinopathy type 3 and lung cancer. An important gene associated with Autoimmune Polyglandular Syndrome Type 3 is CYP21A2 (Cytochrome P450 Family 21 Subfamily A Member 2). Affiliated tissues include cortex, thyroid and adrenal gland.

Related Diseases for Autoimmune Polyglandular Syndrome Type 3

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Diseases in the Autoimmune Polyglandular Syndrome Type 2 family:

autoimmune polyglandular syndrome type 3

Diseases related to Autoimmune Polyglandular Syndrome Type 3 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1autoimmune polyendocrinopathy type 311.6
2lung cancer10.3
3tangier disease10.3
4hepatitis10.3
5keratoconus10.3
6urethritis10.3
7lateral sclerosis10.3
8interstitial lung disease10.3
9hepatitis e10.3
10pancreatitis10.3
11lymphoepithelioma-like carcinoma10.3
12neuronitis10.3
13lung disease10.3
14left ventricular outflow tract obstruction10.3

Graphical network of diseases related to Autoimmune Polyglandular Syndrome Type 3:



Diseases related to autoimmune polyglandular syndrome type 3

Symptoms for Autoimmune Polyglandular Syndrome Type 3

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Drugs & Therapeutics for Autoimmune Polyglandular Syndrome Type 3

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Autoimmune Polyglandular Syndrome Type 3

Genetic Tests for Autoimmune Polyglandular Syndrome Type 3

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Anatomical Context for Autoimmune Polyglandular Syndrome Type 3

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MalaCards organs/tissues related to Autoimmune Polyglandular Syndrome Type 3:

33
Cortex, Thyroid, Adrenal gland, Adrenal cortex, Brain, Breast, Spinal cord

Animal Models for Autoimmune Polyglandular Syndrome Type 3 or affiliated genes

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Publications for Autoimmune Polyglandular Syndrome Type 3

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Articles related to Autoimmune Polyglandular Syndrome Type 3:

(show all 12)
idTitleAuthorsYear
1
Pilomyxoid astrocytoma involving the entire spinal cord in a newborn. (27106533)
2016
2
Radiofrequency ablation in the management of Barrett's esophagus - preliminary own experience. (23837094)
2013
3
Bilateral first branchial cleft anomaly with evidence of a genetic aetiology. (24042065)
2013
4
Postoperative cardiac homograft involvement in Erdheim-Chester disease. (22808847)
2012
5
Mothers' knowledge about acute rheumatic fever. (19006950)
2008
6
Vulval intraepithelial neoplasia and periungual Bowen's disease concordant for mucosal (HPV-34) and epidermodysplasia verruciformis (HPV-21) human papillomavirus types. (17362236)
2007
7
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. (12091878)
2002
8
An extremely uncommon infection: Candida glabrata arthritis after total knee arthroplasty. (12069030)
2002
9
Wernicke-Korsakoff syndrome following small bowel obstruction. (12446948)
2001-2002
10
BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic. Institut Curie Breast Cancer Group. (9150149)
1997
11
Isolation and cloning of a voltage-dependent anion channel-like Mr 36,000 polypeptide from mammalian brain. (1373732)
1992
12
Thymic lymphosarcoma in magnesium-deficient rats. (24277119)
1979

Variations for Autoimmune Polyglandular Syndrome Type 3

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Expression for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

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Search GEO for disease gene expression data for Autoimmune Polyglandular Syndrome Type 3.

Pathways for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

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GO Terms for genes affiliated with Autoimmune Polyglandular Syndrome Type 3

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Sources for Autoimmune Polyglandular Syndrome Type 3

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet