Aliases & Classifications for Autonomic Dysfunction

MalaCards integrated aliases for Autonomic Dysfunction:

Name: Autonomic Dysfunction 50
Autonomic Nervous System Disorders 69
Autonomic Disorder 51

Classifications:



External Ids:

UMLS 69 C1145628

Summaries for Autonomic Dysfunction

NINDS : 50 Dysautonomia refers to a disorder of autonomic nervous system (ANS) function that generally involves failure of the sympathetic or parasympathetic components of the ANS, but dysautonomia involving excessive or overactive ANS actions also can occur. Dysautonomia can be local, as in reflex sympathetic dystrophy, or generalized, as in pure autonomic failure. It can be acute and reversible, as in Guillain-Barre syndrome, or chronic and progressive. Several common conditions such as diabetes and alcoholism can include dysautonomia. Dysautonomia also can occur as a primary condition or in association with degenerative neurological diseases such as Parkinson's disease. Other diseases with generalized, primary dysautonomia include multiple system atrophy and familial dysautonomia. Hallmarks of generalized dysautonomia due to sympathetic failure are impotence (in men) and a fall in blood pressure during standing (orthostatic hypotension). Excessive sympathetic activity can present as hypertension or a rapid pulse rate.

MalaCards based summary : Autonomic Dysfunction, also known as autonomic nervous system disorders, is related to neuropathy, hereditary sensory and autonomic, type iia and multiple system atrophy 1, and has symptoms including sleeplessness, vomiting alone and increased sweating. An important gene associated with Autonomic Dysfunction is ECE1 (Endothelin Converting Enzyme 1), and among its related pathways/superpathways are Neuroscience and Parkinsons Disease Pathway. The drugs Dopamine and Metoprolol have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and brain, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 72 Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does... more...

Related Diseases for Autonomic Dysfunction

Diseases related to Autonomic Dysfunction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 287)
# Related Disease Score Top Affiliating Genes
1 neuropathy, hereditary sensory and autonomic, type iia 30.9 RETREG1 SCN9A WNK1
2 multiple system atrophy 1 29.8 DBH SNCA
3 orthostatic intolerance 29.5 DBH ECE1
4 neuropathy 29.4 RETREG1 SPTLC1 WNK1
5 pure autonomic failure 29.3 DBH SNCA
6 hypertension, essential 29.1 DBH ECE1 WNK1
7 autonomic neuropathy 28.8 RETREG1 SPTLC1 WNK1
8 parkinson disease, late-onset 28.4 DBH SNCA UCHL1
9 hirschsprung disease, cardiac defects, and autonomic dysfunction 12.4
10 pitt-hopkins syndrome 11.5
11 dysautonomia 11.2
12 neuroleptic malignant syndrome 11.1
13 parkinson disease 5, autosomal dominant 10.9
14 perry syndrome 10.9
15 aromatic l-amino acid decarboxylase deficiency 10.9
16 spastic paraplegia 2, x-linked 10.9
17 parkinson disease 4, autosomal dominant 10.9
18 indifference to pain, congenital, autosomal recessive 10.9
19 opsoclonus-myoclonus syndrome 10.9
20 autonomic nervous system disease 10.9
21 neuropathy, hereditary sensory and autonomic, type ia 10.9
22 neuronal intranuclear inclusion disease 10.9
23 neuropathy, hereditary sensory and autonomic, type iib 10.9
24 riboflavin transporter deficiency 10.9
25 paroxysmal extreme pain disorder 10.9
26 neuropathy, hereditary sensory and autonomic, type ic 10.9
27 harlequin syndrome 10.7
28 multiple sclerosis 10.2
29 body mass index quantitative trait locus 18 10.1
30 body mass index quantitative trait locus 4 10.1
31 body mass index quantitative trait locus 9 10.1
32 body mass index quantitative trait locus 12 10.1
33 body mass index quantitative trait locus 10 10.1
34 body mass index quantitative trait locus 14 10.1
35 body mass index quantitative trait locus 8 10.1
36 body mass index quantitative trait locus 11 10.1
37 body mass index quantitative trait locus 7 10.1
38 diabetes mellitus 10.1
39 episodic pain syndrome, familial, 1 10.1
40 dementia 10.0
41 cocaine abuse 10.0 DBH SNCA
42 aging 9.9
43 ataxia and polyneuropathy, adult-onset 9.9
44 epilepsy 9.9
45 liver disease 9.9
46 sleep apnea 9.9
47 polyneuropathy 9.9
48 spinal cord injury 9.9
49 brain injury 9.9
50 chagas disease 9.9

Graphical network of the top 20 diseases related to Autonomic Dysfunction:



Diseases related to Autonomic Dysfunction

Symptoms & Phenotypes for Autonomic Dysfunction

UMLS symptoms related to Autonomic Dysfunction:


sleeplessness, vomiting alone, increased sweating, vertigo/dizziness, blackout - symptom, vomiting in newborn, anal pain, hyperemesis, syncope, effort, pounding heart, palpitations - fluttering, dry throat, warm skin, rectal tenesmus, decrease in appetite, lightheadedness, chronic pain, vomiting, tremor, syncope, seizures, sciatica, rectal pain, pain, mydriasis, headache, diarrhea, constipation, back pain

MGI Mouse Phenotypes related to Autonomic Dysfunction:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.85 DBH RETREG1 SCN9A SNCA SPTLC1 UCHL1
2 growth/size/body region MP:0005378 9.8 DBH ECE1 SCN9A SNCA UCHL1 WNK1
3 integument MP:0010771 9.73 DBH ECE1 RETREG1 SCN9A SNCA UCHL1
4 mortality/aging MP:0010768 9.7 WNK1 DBH ECE1 SCN9A SNCA SPTLC1
5 nervous system MP:0003631 9.56 DBH ECE1 RETREG1 SCN9A SNCA SPTLC1
6 renal/urinary system MP:0005367 8.92 SCN9A SNCA UCHL1 WNK1

Drugs & Therapeutics for Autonomic Dysfunction

Drugs for Autonomic Dysfunction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 495)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
2
Metoprolol Approved, Investigational Phase 4,Phase 2,Phase 1 51384-51-1, 37350-58-6 4171
3
Acetylcholine Approved Phase 4 51-84-3 187
4
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
5
Midodrine Approved Phase 4,Phase 3,Phase 2,Phase 1 42794-76-3, 133163-28-7 4195
6
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
7
Bupivacaine Approved, Investigational Phase 4,Phase 3 38396-39-3, 2180-92-9 2474
8
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
9 Zotepine Approved, Investigational Phase 4 26615-21-4
10
Zolpidem Approved Phase 4 82626-48-0 5732
11
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
12
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
13
Levodopa Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-92-7 6047
14
Propranolol Approved, Investigational Phase 4,Phase 1,Phase 2,Early Phase 1 525-66-6 4946
15
Fludrocortisone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 127-31-1 31378
16
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23651-95-8 443940
17
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
18
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 1
19
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
20
Bisoprolol Approved Phase 4 66722-44-9 2405
21
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Early Phase 1 50-81-7 54670067 5785
22 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3
23
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
24 triamcinolone acetonide Phase 4,Phase 3
25
Serotonin Phase 4,Phase 2,Phase 1,Early Phase 1 50-67-9 5202
26 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
27 Dopamine agonists Phase 4,Phase 1
28 abobotulinumtoxinA Phase 4
29 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
30 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
33 Serotonin Agents Phase 4,Phase 2,Phase 1,Early Phase 1
34 Serotonin Antagonists Phase 4
35 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Adrenergic Antagonists Phase 4,Phase 2,Phase 1,Early Phase 1
37 Adrenergic beta-1 Receptor Antagonists Phase 4,Phase 2,Phase 1
38 N 0437 Phase 4
39 Adrenergic beta-Antagonists Phase 4,Phase 2,Phase 1,Early Phase 1
40 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 GABA Agents Phase 4,Early Phase 1
42 GABA Agonists Phase 4
43 GABA-A Receptor Agonists Phase 4
44 Sympatholytics Phase 4,Phase 3,Phase 2,Phase 1
45 Neuromuscular Agents Phase 4
46 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
47 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
49 Triamcinolone diacetate Phase 4,Phase 3
50 Triamcinolone hexacetonide Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 509)

# Name Status NCT ID Phase Drugs
1 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Unknown status NCT01823770 Phase 4 Rotigotine;Placebo patchs
2 Risperidone and Zotepine in the Treatment of Delirium Unknown status NCT00622011 Phase 4 Risperidone and Zolpidem for delirium
3 Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) Unknown status NCT01621464 Phase 4
4 Botulinum A Toxin in Patients With Parkinson's Disease Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
5 Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI Unknown status NCT02298660 Phase 4 BOTOX
6 Duodenal Levodopa Infusion, Quality of Life and Autonomic Nervous System in Parkinson's Disease Completed NCT00914134 Phase 4 Levodopa infusion
7 Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises Completed NCT02004405 Phase 4
8 Using Propranolol in Traumatic Brain Injury to Reduce Sympathetic Storm Phenomenon Completed NCT03401515 Phase 4 Propranolol Hydrochloride 1 MG/ML
9 Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy Completed NCT01524861 Phase 4 Placebo;alpha-lipoic acid;L-acetyl carnitine
10 Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Completed NCT00060866 Phase 4 Propranolol
11 Prophylactic Administration of Vitamin C in Wrist Fractures Completed NCT00296868 Phase 4 ascorbic acid (vitamin C) versus placebo
12 Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study Completed NCT02308124 Phase 4 Midodrine;Pyridostigmine Bromide;Midodrine + pyridostigmine
13 Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01518946 Phase 4 Midodrine HCl;Placebo
14 Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01515865 Phase 4 Midodrine HCl;Placebo
15 Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension Completed NCT00555880 Phase 4 Midodrine hydrochloride;Placebo
16 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4 Midodrine Hydrochloride
17 Clinical Trial for the Prevention of Vasovagal Syncope Completed NCT00118482 Phase 4 fludrocortisone acetate
18 Restore Claims Characterization Study Completed NCT00200122 Phase 4
19 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
20 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
21 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4 Droxidopa capsules;Placebo capsules
22 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4 vildagliptin;Dapagliflozin
23 Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OH Recruiting NCT03350659 Phase 4 Midodrine;Atomoxetine
24 Dawn Simulation and Postural Hypotension Recruiting NCT02632318 Phase 4
25 Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Recruiting NCT02123056 Phase 4 Metoprolol;Matching Placebo
26 Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV Recruiting NCT01456481 Phase 4 midodrine hydrochloride;matching placebo
27 Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors Active, not recruiting NCT03098368 Phase 4 Rotigotine;Placebo
28 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
29 Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) Active, not recruiting NCT02171988 Phase 4 Propranolol;Bisoprolol;Propranolol+pyridostigmine;Bisoprolol+pyridostgmine
30 Brain Perfusion & Oxygenation in Parkinson's Disease With NOH Not yet recruiting NCT03229174 Phase 4 Droxidopa;Placebo
31 Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome Not yet recruiting NCT03291197 Phase 4 Suprascapular and median nerve blocks
32 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4 midodrine hydrochloride (ProAmatine®)
33 A Study Evaluating Hypotension and Autonomic Nervous System Dysfunction in Multiple Myeloma (MM) Patients Unknown status NCT01314625 Phase 3
34 Clinical Trial on the Effectiveness of Traditional Chinese Medicinal Mixture in Parkinson Disease Unknown status NCT00629161 Phase 2, Phase 3 Traditional Chinese Medicinal Mixture (composed of Roucongrong and adjuvant);placebo
35 Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II) Unknown status NCT01392599 Phase 3
36 Post-Exercise Hypotension in Elderly Hypertensive Men Unknown status NCT02415582 Phase 3
37 Acupuncture for Post-stroke Shoulder-hand Syndrome Unknown status NCT02011854 Phase 2, Phase 3
38 RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb Unknown status NCT01612364 Phase 3
39 Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block Unknown status NCT01134289 Phase 3
40 Intravenous Immunoglobulins in Complex-regional Pain Syndrome Unknown status NCT00949065 Phase 3
41 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
42 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3 Carbidopa;Placebo
43 Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis Completed NCT00409175 Phase 2, Phase 3 Fx-1006A;Placebo
44 The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury Completed NCT02099890 Phase 3
45 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3 Double blinded IVIg
46 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304) Completed NCT01132326 Phase 3 Droxidopa
47 A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa Completed NCT00782340 Phase 3 Placebo;Droxidopa
48 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00633880 Phase 3 Placebo;Droxidopa
49 Clinical Trial on the Effectiveness of Herbal Medicinal Mixture in Parkinson Disease Completed NCT00656253 Phase 2, Phase 3 Herbal Medicinal Mixture (Roucongrong, Heshouwu etc.);Placebo
50 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3 Droxidopa;Placebo

Search NIH Clinical Center for Autonomic Dysfunction

Genetic Tests for Autonomic Dysfunction

Anatomical Context for Autonomic Dysfunction

MalaCards organs/tissues related to Autonomic Dysfunction:

38
Heart, Spinal Cord, Brain, Testes, Liver, Cortex, Bone

Publications for Autonomic Dysfunction

Articles related to Autonomic Dysfunction:

(show top 50) (show all 691)
# Title Authors Year
1
Acute interruption of treatment with nandrolone decanoate is not sufficient to reverse cardiac autonomic dysfunction and ventricular repolarization disturbances in rats. ( 29366731 )
2018
2
Higher body mass index predicts cardiac autonomic dysfunction: A longitudinal study in adolescent type 1 diabetes. ( 29383813 )
2018
3
Autonomic dysfunction predicts poor outcome in stroke: Updates on recent autonomic research. ( 29305815 )
2018
4
Cardiovascular autonomic dysfunction in sudden infant death syndrome. ( 29299712 )
2018
5
Autonomic dysfunction in Parkinson's disease and other synucleinopathies: Introduction to the series. ( 29436737 )
2018
6
Lateral medullary infarction with cardiovascular autonomic dysfunction: an unusual presentation with review of the literature. ( 29368226 )
2018
7
Cardiovascular Autonomic Dysfunction: Link Between Multiple Sclerosis Osteoporosis and Neurodegeneration. ( 29429076 )
2018
8
Cardiovascular autonomic dysfunction in patients with idiopathic diabetes insipidus. ( 29081004 )
2018
9
Markers of cardiovascular autonomic dysfunction predict COPD in middle-aged subjects. ( 29419441 )
2018
10
Patients with primary restless legs syndrome have higher prevalence of autonomic dysfunction and irritable bowel syndrome. ( 29372261 )
2018
11
Atrial Arrhythmias and Autonomic Dysfunction in Rats Exposed to Chronic Intermittent Hypoxia. ( 29424572 )
2018
12
Autonomic Dysfunction Predicts Clinical Outcomes After Acute Ischemic Stroke: A Prospective Observational Study. ( 29203690 )
2018
13
Neuropathology of autonomic dysfunction in synucleinopathies. ( 29297596 )
2018
14
Autonomic dysfunction as a mechanism of intradialytic blood pressure instability. ( 28730673 )
2017
15
Autonomic dysfunction in a patient with X-linked adrenoleukodystrophy. ( 29284317 )
2017
16
Peduncular Hallucinosis and Autonomic Dysfunction in Anti-Aquaporin-4 Antibody Syndrome. ( 28926419 )
2017
17
Cardiovascular Autonomic Dysfunction in Children and Adolescents With Rett Syndrome. ( 28351539 )
2017
18
Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced left ventricular ejection fraction: Design and rationale of the SMART-MI trial. ( 28760211 )
2017
19
Circadian rhythm and autonomic dysfunction in presymptomatic and early Huntington's disease. ( 28935191 )
2017
20
A Case of Recurrent Hypersomnia With Autonomic Dysfunction. ( 28633719 )
2017
21
Ataxia and autonomic dysfunction as presenting symptoms in late-onset Alexander disease. ( 29431177 )
2017
22
Infectious diseases causing autonomic dysfunction. ( 28730326 )
2017
23
Paediatric breath-holding spells are associated with autonomic dysfunction and iron deficiency may play a role. ( 29210110 )
2017
24
Vitamin D in the Spectrum of Prediabetes and Cardiovascular Autonomic Dysfunction. ( 28768837 )
2017
25
Autonomic dysfunction plays a decisive role in the arrhythmia initiation, whereas metabolic disorders facilitate further atrial remodeling in antipsychotic-related atrial fibrillation. ( 28712564 )
2017
26
A novel mutation in GMPPA in siblings with apparent intellectual disability, epilepsy, dysmorphism, and autonomic dysfunction. ( 28574218 )
2017
27
Orthostatic Hypotension in Patients With Left Ventricular Assist Devices: Acquired Autonomic Dysfunction. ( 28799950 )
2017
28
The Prevalence and Severity of Autonomic Dysfunction in Chronic Inflammatory Demyelinating Polyneuropathy. ( 28904461 )
2017
29
Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases. ( 29445550 )
2017
30
Severity of traumatic brain injury correlates with long-term cardiovascular autonomic dysfunction. ( 28770375 )
2017
31
Cardiovascular autonomic dysfunction in women with polycystic ovary syndrome: a systematic review and meta-analysis. ( 28483340 )
2017
32
Autonomic dysfunction in Parkinson's disease: A prospective cohort study. ( 29278286 )
2017
33
REM sleep behavior disorder, autonomic dysfunction and synuclein-related neurodegeneration: where do we stand? ( 28871332 )
2017
34
Cardiovascular autonomic dysfunction predicts increasing albumin excretion in type 1 diabetes. ( 29171134 )
2017
35
Lower urinary tract autonomic dysfunction evaluation in spinal cord injury patients: an applied example. ( 29423301 )
2017
36
Acute onset autonomic dysfunction and orthostatic syncope as an early manifestation of HIV infection. ( 28856462 )
2017
37
Autonomic Dysfunction after Mild Traumatic Brain Injury. ( 28800081 )
2017
38
Autonomic Dysfunction in Parkinson's Disease: Cardiovascular Symptoms, Thermoregulation, and Urogenital Symptoms. ( 28805582 )
2017
39
Fat intake and cardiac autonomic dysfunction in obese children: What is the relationship? ( 28673780 )
2017
40
Dante Alighieri: evidence for sleep disorder-related cardiac autonomic dysfunctions. ( 28000594 )
2017
41
Acute Effect of Aerobic and Strength Exercise on Heart Rate Variability and Baroreflex Sensitivity in Men with Autonomic Dysfunction. ( 29271835 )
2017
42
Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction. ( 28779001 )
2017
43
Autonomic dysfunction: A guide for FPs. ( 28863200 )
2017
44
A Plasma Cell Dyscrasia Presenting as Amyloid Cardiomyopathy and Autonomic Dysfunction in a Healthy Patient. ( 28861330 )
2017
45
Is Vitamin D Deficiency Implicated in Autonomic Dysfunction? ( 28904566 )
2017
46
Overactive bladder and autonomic dysfunction: Lower urinary tract symptoms in females with postural tachycardia syndrome. ( 26859225 )
2017
47
Hereditary angioedema: Assessing the hypothesis for underlying autonomic dysfunction. ( 29107952 )
2017
48
Pupillary autonomic dysfunction in patients with ANCA-associated vasculitis. ( 28864843 )
2017
49
Respiratory and autonomic dysfunction in congenital central hypoventilation syndrome. ( 27226447 )
2016
50
Autonomic dysfunction in primary Sjogren's syndrome: a prospective cohort analysis of 154 Korean patients. ( 27017389 )
2016

Variations for Autonomic Dysfunction

Expression for Autonomic Dysfunction

Search GEO for disease gene expression data for Autonomic Dysfunction.

Pathways for Autonomic Dysfunction

Pathways related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 DBH SCN9A SNCA UCHL1
2 11.08 SNCA UCHL1
3 10.46 SNCA UCHL1

GO Terms for Autonomic Dysfunction

Cellular components related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.23 DBH ECE1 RETREG1 SCN9A SNCA SPTLC1

Biological processes related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of receptor recycling GO:0001921 8.96 ECE1 SNCA
2 sensory perception of pain GO:0019233 8.8 RETREG1 SCN9A UCHL1

Molecular functions related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 copper ion binding GO:0005507 8.62 DBH SNCA

Sources for Autonomic Dysfunction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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