Aliases & Classifications for Autonomic Dysfunction

MalaCards integrated aliases for Autonomic Dysfunction:

Name: Autonomic Dysfunction 51
Autonomic Nervous System Disorders 69
Autonomic Disorder 52

Summaries for Autonomic Dysfunction

NINDS : 51 Dysautonomia refers to a disorder of autonomic nervous system (ANS) function that generally involves failure of the sympathetic or parasympathetic components of the ANS, but dysautonomia involving excessive or overactive ANS actions also can occur. Dysautonomia can be local, as in reflex sympathetic dystrophy, or generalized, as in pure autonomic failure. It can be acute and reversible, as in Guillain-Barre syndrome, or chronic and progressive. Several common conditions such as diabetes and alcoholism can include dysautonomia. Dysautonomia also can occur as a primary condition or in association with degenerative neurological diseases such as Parkinson's disease. Other diseases with generalized, primary dysautonomia include multiple system atrophy and familial dysautonomia. Hallmarks of generalized dysautonomia due to sympathetic failure are impotence (in men) and a fall in blood pressure during standing (orthostatic hypotension). Excessive sympathetic activity can present as hypertension or a rapid pulse rate.

MalaCards based summary : Autonomic Dysfunction, also known as autonomic nervous system disorders, is related to hirschsprung disease, cardiac defects, and autonomic dysfunction and pitt-hopkins syndrome, and has symptoms including back pain, constipation and diarrhea. An important gene associated with Autonomic Dysfunction is ECE1 (Endothelin Converting Enzyme 1), and among its related pathways/superpathways are Neuroscience and Parkinsons Disease Pathway. The drugs Dopamine and Risperidone have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and endothelial, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 72 Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does... more...

Related Diseases for Autonomic Dysfunction

Diseases related to Autonomic Dysfunction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 218)
id Related Disease Score Top Affiliating Genes
1 hirschsprung disease, cardiac defects, and autonomic dysfunction 12.3
2 pitt-hopkins syndrome 11.2
3 dysautonomia 11.1
4 neuroleptic malignant syndrome 11.0
5 perry syndrome 10.7
6 paroxysmal extreme pain disorder 10.7
7 insensitivity to pain, congenital 10.7
8 parkinson disease 5 10.7
9 parkinson disease 4 10.7
10 neuropathy, hereditary sensory and autonomic, type iib 10.7
11 aromatic l-amino acid decarboxylase deficiency 10.7
12 neuropathy, hereditary sensory and autonomic, type ia 10.7
13 dysautonomia, familial 10.7
14 neuropathy, hereditary sensory and autonomic, type ii 10.7
15 neuropathy, hereditary sensory and autonomic, type ic 10.7
16 spastic paraplegia 2, x-linked 10.7
17 opsoclonus-myoclonus syndrome 10.7
18 riboflavin transporter deficiency 10.7
19 obesity 10.1
20 pyogenic arthritis, pyoderma gangrenosum and acne 10.0 DBH SNCA
21 parietal foramina 3 10.0 DBH SNCA
22 dementia 9.9
23 multiple system atrophy 9.9
24 neuropathy 9.9
25 celiac disease 12 9.9 SNCA UCHL1
26 bladder hepatoid adenocarcinoma 9.9 DBH SNCA
27 orthostatic intolerance 9.9
28 brain injury 9.9
29 liver disease 9.9
30 sleep apnea 9.9
31 chagas disease 9.9
32 polyneuropathy 9.9
33 arthritis 9.8
34 polycystic ovary syndrome 9.8
35 spinal cord injury 9.8
36 traumatic brain injury 9.8
37 obstructive sleep apnea 9.8
38 epilepsy 9.8
39 cerebritis 9.8
40 ataxia 9.8
41 piebald trait, kit-related 9.8 SNCA UCHL1
42 rheumatoid arthritis 9.8
43 myocardial infarction 9.8
44 machado-joseph disease 9.8
45 tetanus 9.8
46 sleep disorder 9.8
47 postural orthostatic tachycardia syndrome 9.8
48 syncope 9.8
49 schizophrenia 9.7
50 cerebellar ataxia 9.7

Graphical network of the top 20 diseases related to Autonomic Dysfunction:



Diseases related to Autonomic Dysfunction

Symptoms & Phenotypes for Autonomic Dysfunction

UMLS symptoms related to Autonomic Dysfunction:


back pain, constipation, diarrhea, headache, mydriasis, pain, rectal pain, sciatica, seizures, syncope, tremor, vomiting, chronic pain, lightheadedness, rectal tenesmus, warm skin, dry throat, palpitations - fluttering, pounding heart, syncope, effort, hyperemesis, anal pain, vomiting in newborn, blackout - symptom, vertigo/dizziness, increased sweating, vomiting alone, sleeplessness

MGI Mouse Phenotypes related to Autonomic Dysfunction:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.85 SCN9A SNCA SPTLC1 UCHL1 DBH RETREG1
2 growth/size/body region MP:0005378 9.8 SCN9A SNCA UCHL1 DBH WNK1 ECE1
3 integument MP:0010771 9.73 SCN9A SNCA UCHL1 DBH ECE1 RETREG1
4 mortality/aging MP:0010768 9.7 SCN9A SNCA SPTLC1 UCHL1 DBH WNK1
5 nervous system MP:0003631 9.56 SNCA SPTLC1 UCHL1 DBH WNK1 ECE1
6 renal/urinary system MP:0005367 8.92 SCN9A SNCA UCHL1 WNK1

Drugs & Therapeutics for Autonomic Dysfunction

Drugs for Autonomic Dysfunction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 502)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
2
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
3
Zolpidem Approved Phase 4 82626-48-0 5732
4 Zotepine Approved Phase 4 26615-21-4
5
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
6
Acetylcholine Approved Phase 4 51-84-3 187
7
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
8
Midodrine Approved Phase 4,Phase 3,Phase 2,Phase 1 133163-28-7, 42794-76-3 4195
9
Fludrocortisone Approved Phase 4,Phase 2,Phase 1 127-31-1 31378
10
Metoprolol Approved, Investigational Phase 4,Phase 2,Phase 1 37350-58-6, 51384-51-1 4171
11
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
12
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
13
Levodopa Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-92-7 6047
14
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 1
15
Propranolol Approved, Investigational Phase 4,Phase 1,Phase 2,Early Phase 1 525-66-6 4946
16
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
17
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23651-95-8 443940
18
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
19
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
20
Bisoprolol Approved Phase 4 66722-44-9 2405
21 tannic acid Approved, Nutraceutical Phase 4
22
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Early Phase 1 50-81-7 5785 54670067
23
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
24
gamma-Aminobutyric acid Investigational Phase 4 56-12-2 119
25 Antipsychotic Agents Phase 4,Phase 3
26 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Dopamine Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Dopamine Antagonists Phase 4,Phase 3,Phase 1
29 GABA Agents Phase 4,Early Phase 1
30 GABA Agonists Phase 4
31 GABA-A Receptor Agonists Phase 4
32 Hypnotics and Sedatives Phase 4,Phase 1,Early Phase 1
33 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
35
Serotonin Phase 4,Phase 2,Phase 1,Early Phase 1 50-67-9 5202
36 Serotonin Agents Phase 4,Phase 2,Phase 1,Early Phase 1
37 Serotonin Antagonists Phase 4
38 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Dopamine agonists Phase 4,Phase 1
40 N 0437 Phase 4
41 abobotulinumtoxinA Phase 4
42 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Botulinum Toxins Phase 4
44 Botulinum Toxins, Type A Phase 4
45 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Neuromuscular Agents Phase 4
47 onabotulinumtoxinA Phase 4
48 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
49 Adjuvants, Immunologic Phase 4,Phase 2,Phase 1,Early Phase 1
50 Benphothiamine Phase 4

Interventional clinical trials:

(show top 50) (show all 527)

id Name Status NCT ID Phase Drugs
1 Risperidone and Zotepine in the Treatment of Delirium Unknown status NCT00622011 Phase 4 Risperidone and Zolpidem for delirium
2 Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome Unknown status NCT01823770 Phase 4 Rotigotine;Placebo patchs
3 Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI Unknown status NCT02298660 Phase 4 BOTOX
4 Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) Unknown status NCT01621464 Phase 4
5 Botulinum A Toxin in Patients With Parkinson's Disease Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
6 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4 Benfotiamine;Placebo
7 Duodenal Levodopa Infusion, Quality of Life and Autonomic Nervous System in Parkinson's Disease Completed NCT00914134 Phase 4 Levodopa infusion
8 Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises Completed NCT02004405 Phase 4
9 Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy Completed NCT01524861 Phase 4 Placebo;alpha-lipoic acid;L-acetyl carnitine
10 Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Completed NCT00060866 Phase 4 Propranolol
11 Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study Completed NCT00466778 Phase 4
12 Prophylactic Administration of Vitamin C in Wrist Fractures Completed NCT00296868 Phase 4 ascorbic acid (vitamin C) versus placebo
13 Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study Completed NCT02308124 Phase 4 Midodrine;Pyridostigmine Bromide;Midodrine + pyridostigmine
14 Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01518946 Phase 4 Midodrine HCl;Placebo
15 Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01515865 Phase 4 Midodrine HCl;Placebo
16 Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension Completed NCT00555880 Phase 4 Midodrine hydrochloride;Placebo
17 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4 Midodrine Hydrochloride
18 Clinical Trial for the Prevention of Vasovagal Syncope Completed NCT00118482 Phase 4 fludrocortisone acetate
19 Evaluation of the Autonomic Nervous System During First-dosing With 0.5mg of Fingolimod (Gilenya) in Patients With Relapsing-remitting MS Completed NCT02048072 Phase 4 Gilenya
20 Restore Claims Characterization Study Completed NCT00200122 Phase 4
21 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
22 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
23 Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer Completed NCT01912586 Phase 4
24 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4 Droxidopa capsules;Placebo capsules
25 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4 vildagliptin;Dapagliflozin
26 Dawn Simulation and Postural Hypotension Recruiting NCT02632318 Phase 4
27 Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Recruiting NCT02123056 Phase 4 Metoprolol;Matching Placebo
28 Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV Recruiting NCT01456481 Phase 4 midodrine hydrochloride;matching placebo
29 Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments Recruiting NCT03149419 Phase 4 Paroxetine;Placebo oral capsule
30 Interstitial Cystitis: Examination of the Central Autonomic Network Recruiting NCT03008382 Phase 4 Metoprolol Oral Tablet;Placebo Oral Tablet
31 Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors Active, not recruiting NCT03098368 Phase 4 Rotigotine;Placebo
32 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
33 Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) Active, not recruiting NCT02171988 Phase 4 Propranolol;Bisoprolol;Propranolol+pyridostigmine;Bisoprolol+pyridostgmine
34 Brain Perfusion & Oxygenation in Parkinson's Disease With NOH Not yet recruiting NCT03229174 Phase 4 Droxidopa;Placebo
35 Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome Not yet recruiting NCT03291197 Phase 4 Suprascapular and median nerve blocks
36 Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome Terminated NCT00780390 Phase 4
37 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4 midodrine hydrochloride (ProAmatine®)
38 A Study Evaluating Hypotension and Autonomic Nervous System Dysfunction in Multiple Myeloma (MM) Patients Unknown status NCT01314625 Phase 3
39 Clinical Trial on the Effectiveness of Traditional Chinese Medicinal Mixture in Parkinson Disease Unknown status NCT00629161 Phase 2, Phase 3 Traditional Chinese Medicinal Mixture (composed of Roucongrong and adjuvant);placebo
40 Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II) Unknown status NCT01392599 Phase 3
41 Post-Exercise Hypotension in Elderly Hypertensive Men Unknown status NCT02415582 Phase 3
42 Acupuncture for Post-stroke Shoulder-hand Syndrome Unknown status NCT02011854 Phase 2, Phase 3
43 RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb Unknown status NCT01612364 Phase 3
44 Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block Unknown status NCT01134289 Phase 3
45 Intravenous Immunoglobulins in Complex-regional Pain Syndrome Unknown status NCT00949065 Phase 3
46 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
47 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3 Carbidopa;Placebo
48 Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis Completed NCT00409175 Phase 2, Phase 3 Fx-1006A;Placebo
49 The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury Completed NCT02099890 Phase 3
50 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3 Double blinded IVIg

Search NIH Clinical Center for Autonomic Dysfunction

Genetic Tests for Autonomic Dysfunction

Anatomical Context for Autonomic Dysfunction

MalaCards organs/tissues related to Autonomic Dysfunction:

39
Heart, Spinal Cord, Endothelial, Brain, Testes, Liver, Cortex

Publications for Autonomic Dysfunction

Articles related to Autonomic Dysfunction:

(show top 50) (show all 669)
id Title Authors Year
1
REM sleep behavior disorder, autonomic dysfunction and synuclein-related neurodegeneration: where do we stand? ( 28871332 )
2017
2
Orthostatic Hypotension in Patients With Left Ventricular Assist Devices: Acquired Autonomic Dysfunction. ( 28799950 )
2017
3
Severity of traumatic brain injury correlates with long-term cardiovascular autonomic dysfunction. ( 28770375 )
2017
4
Fat intake and cardiac autonomic dysfunction in obese children: What is the relationship? ( 28673780 )
2017
5
Autonomic Dysfunction in Parkinson's Disease: Cardiovascular Symptoms, Thermoregulation, and Urogenital Symptoms. ( 28805582 )
2017
6
Overactive bladder and autonomic dysfunction: Lower urinary tract symptoms in females with postural tachycardia syndrome. ( 26859225 )
2017
7
Circadian rhythm and autonomic dysfunction in presymptomatic and early Huntington's disease. ( 28935191 )
2017
8
Is Vitamin D Deficiency Implicated in Autonomic Dysfunction? ( 28904566 )
2017
9
Infectious diseases causing autonomic dysfunction. ( 28730326 )
2017
10
A Plasma Cell Dyscrasia Presenting as Amyloid Cardiomyopathy and Autonomic Dysfunction in a Healthy Patient. ( 28861330 )
2017
11
Vitamin D in the Spectrum of Prediabetes and Cardiovascular Autonomic Dysfunction. ( 28768837 )
2017
12
Cardiovascular Autonomic Dysfunction in Children and Adolescents With Rett Syndrome. ( 28351539 )
2017
13
Peduncular Hallucinosis and Autonomic Dysfunction in Anti-Aquaporin-4 Antibody Syndrome. ( 28926419 )
2017
14
Autonomic dysfunction as a mechanism of intradialytic blood pressure instability. ( 28730673 )
2017
15
Autonomic Dysfunction after Mild Traumatic Brain Injury. ( 28800081 )
2017
16
Acute onset autonomic dysfunction and orthostatic syncope as an early manifestation of HIV infection. ( 28856462 )
2017
17
Cardiovascular autonomic dysfunction in women with polycystic ovary syndrome: a systematic review and meta-analysis. ( 28483340 )
2017
18
Dante Alighieri: evidence for sleep disorder-related cardiac autonomic dysfunctions. ( 28000594 )
2017
19
Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction. ( 28779001 )
2017
20
Autonomic dysfunction: A guide for FPs. ( 28863200 )
2017
21
The Prevalence and Severity of Autonomic Dysfunction in Chronic Inflammatory Demyelinating Polyneuropathy. ( 28904461 )
2017
22
Autonomic dysfunction plays a decisive role in the arrhythmia initiation, whereas metabolic disorders facilitate further atrial remodeling in antipsychotic-related atrial fibrillation. ( 28712564 )
2017
23
A Case of Recurrent Hypersomnia With Autonomic Dysfunction. ( 28633719 )
2017
24
Pupillary autonomic dysfunction in patients with ANCA-associated vasculitis. ( 28864843 )
2017
25
Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced left ventricular ejection fraction: Design and rationale of the SMART-MI trial. ( 28760211 )
2017
26
Autonomic dysfunction in first ever ischemic stroke: Prevalence, predictors and short term neurovascular outcome. ( 27588371 )
2016
27
A Practical Approach to Autonomic Dysfunction in Patients with Headache. ( 27021770 )
2016
28
Cardiovascular Autonomic Dysfunction Predicts Diabetic Foot Ulcers in Patients With Type 2 Diabetes Without Diabetic Polyneuropathy. ( 27015188 )
2016
29
Respiratory and autonomic dysfunction in congenital central hypoventilation syndrome. ( 27226447 )
2016
30
Multiscale entropic assessment of autonomic dysfunction in patients with obstructive sleep apnea and therapeutic impact of continuous positive airway pressure treatment. ( 27318220 )
2016
31
Autonomic Dysfunction Precedes Development of Rheumatoid Arthritis: A Prospective Cohort Study. ( 27211565 )
2016
32
Inflammatory markers are associated with cardiac autonomic dysfunction in recent-onset type 2 diabetes. ( 27481890 )
2016
33
Prevalence of Autonomic Dysfunction in Hospitalized Patients with Guillain- Barre Syndrome. ( 28039863 )
2016
34
Is there an association between markers of cardiovascular autonomic dysfunction at discharge from rehabilitation and participation one and five years later in individuals with spinal cord injury? ( 27084265 )
2016
35
Changes in oral cavity during period of intensive vomiting in patient with somatoform autonomic dysfunction - description of the case. ( 27556111 )
2016
36
Autonomic dysfunction in primary sleep disorders. ( 27198946 )
2016
37
OS 29-02 CIRCADIAN BLOOD PRESSURE PROFILE ABNORMALITIES AND AUTONOMIC DYSFUNCTION. ( 27643080 )
2016
38
Autonomic Dysfunction in Critical Illness: ObNOX(2)ious (Baro)reflex Upregulation of G Protein-Coupled Receptor Kinase-2 Lets the Heart Down. ( 27428129 )
2016
39
Pupillary Light Reflexes are Associated with Autonomic Dysfunction in Bolivian Diabetics But Not Chagas Disease Patients. ( 27044564 )
2016
40
Distinctive cardiac autonomic dysfunction following stress exposure in both sexes in an animal model of PTSD. ( 27105958 )
2016
41
Evaluation of Autonomic Dysfunction in Obese and Non-Obese Hypertensive Subjects. ( 27504394 )
2016
42
Examining the Crux of Autonomic Dysfunction in Posttraumatic Stress Disorder: Whether Chronic or Situational Distress Underlies Elevated Heart Rate and Attenuated Heart Rate Variability. ( 27057817 )
2016
43
Cardiovascular Autonomic Dysfunction in Mild and Advanced Parkinson's Disease. ( 27020456 )
2016
44
Juvenile fibromyalgia syndrome: Blunted heart rate response and cardiac autonomic dysfunction at diagnosis. ( 27542737 )
2016
45
Cardiovagal and adrenergic function tests in unilateral carotid artery stenosis patients-a Valsalva manoeuvre tool to show an autonomic dysfunction? ( 26980215 )
2016
46
Autonomic dysfunction in multiple sclerosis is better detected by heart rate variability and is not correlated with central autonomic network damage. ( 27423576 )
2016
47
The role of autonomic dysfunction in cirrhotic patients before and after liver transplantation. Review of the literature. ( 27003923 )
2016
48
Autonomic dysfunction in patients with essential tremor. ( 27812758 )
2016
49
Measures of Autonomic Dysfunction in Diabetic and Idiopathic Gastroparesis. ( 27785328 )
2016
50
Comparison of heart rate variability and classic autonomic testing for detection of cardiac autonomic dysfunction in patients with fibromyalgia. ( 27126923 )
2016

Variations for Autonomic Dysfunction

Expression for Autonomic Dysfunction

Search GEO for disease gene expression data for Autonomic Dysfunction.

Pathways for Autonomic Dysfunction

Pathways related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.43 DBH SCN9A SNCA UCHL1
2 11.08 SNCA UCHL1
3 10.46 SNCA UCHL1

GO Terms for Autonomic Dysfunction

Cellular components related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.23 DBH ECE1 RETREG1 SCN9A SNCA SPTLC1

Biological processes related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of receptor recycling GO:0001921 8.96 ECE1 SNCA
2 sensory perception of pain GO:0019233 8.8 RETREG1 SCN9A UCHL1

Molecular functions related to Autonomic Dysfunction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 copper ion binding GO:0005507 8.62 DBH SNCA

Sources for Autonomic Dysfunction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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