MCID: ATN004
MIFTS: 42

Autonomic Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Autonomic Neuropathy

MalaCards integrated aliases for Autonomic Neuropathy:

Name: Autonomic Neuropathy 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11504
NCIt 47 C27033
SNOMED-CT 64 277879009
UMLS 69 C0259749

Summaries for Autonomic Neuropathy

MalaCards based summary : Autonomic Neuropathy is related to neuropathy, hereditary sensory and autonomic, type v and dyspepsia. An important gene associated with Autonomic Neuropathy is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Neuroscience and Activation of TRKA receptors. The drugs Quinapril and Midodrine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and kidney, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 72 Autonomic neuropathy (also AN or AAN) is a form of polyneuropathy that affects the non-voluntary,... more...

Related Diseases for Autonomic Neuropathy

Diseases related to Autonomic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
id Related Disease Score Top Affiliating Genes
1 neuropathy, hereditary sensory and autonomic, type v 33.7 NGF NTRK1
2 dyspepsia 29.6 CCK NPY
3 pheochromocytoma 29.1 NGF NPY NTRK1
4 calcinosis 28.6 ALB EPO INS
5 diabetic autonomic neuropathy 12.1
6 hereditary sensory and autonomic neuropathy type 1e 12.1
7 idiopathic peripheral autonomic neuropathy 12.0
8 hereditary sensory and autonomic neuropathy type iic 11.9
9 x-linked hereditary sensory and autonomic neuropathy with deafness 11.8
10 hereditary sensory and autonomic neuropathy with deafness and global delay 11.8
11 neuropathy, hereditary sensory and autonomic, type ii 11.8
12 dysautonomia, familial 11.8
13 insensitivity to pain, congenital, with anhidrosis 11.8
14 neuropathy, hereditary sensory and autonomic, type vii 11.7
15 neuropathy, hereditary sensory and autonomic, type vi 11.7
16 neuropathy, hereditary sensory and autonomic, type viii 11.7
17 neuropathy, hereditary sensory, type ie 11.7
18 insensitivity to pain, congenital 11.6
19 neuropathy, hereditary sensory and autonomic, type iib 11.6
20 neuropathy, hereditary sensory and autonomic, type ia 11.6
21 neuropathy, hereditary sensory and autonomic, type ic 11.6
22 neuropathy, hereditary sensory and autonomic, type i, with cough and gastroesophageal reflux 11.6
23 dysautonomia 11.1
24 autonomic dysfunction 11.1
25 diabetic neuropathy 11.1
26 neuropathy 11.0
27 autoimmune autonomic ganglionopathy 10.8
28 deafness, x-linked 5 10.8
29 sensory peripheral neuropathy 10.8
30 neuropathy, hereditary sensory, with spastic paraplegia 10.8
31 prp systemic amyloidosis 10.8
32 autoimmune gastrointestinal dysmotility 10.8
33 lipomatosis, multiple symmetric 10.8
34 hereditary neuropathies 10.8
35 pharynx carcinoma in situ 10.7 NGF NTRK1
36 water-clear cell adenoma 10.7 NGF NTRK1
37 cecum adenoma 10.7 NGF NTRK1
38 erb-duchenne and dejerine-klumpke palsies 10.6 ELP1 NTRK1
39 nephronophthisis 2, infantile 10.6 ELP1 NGF
40 ileocolitis 10.6 ELP1 NGF
41 scleroperikeratitis 10.6 NGF NTRK1
42 hypertrophic osteoarthropathy, primary, autosomal recessive 2 10.5 NTRK1 SPTLC1
43 nephrotic syndrome, type 6 10.4 ELP1 RETREG1 WNK1
44 extratemporal epilepsy 10.4 INS SPTLC1
45 central cervical cord syndrome 10.4 RETREG1 SPTLC1 WNK1
46 chronic lacrimal gland enlargement 10.3 AKR1B1 NGF
47 pancreatic acinar cell adenocarcinoma 10.3 ELP1 INS NGF
48 ulcerative blepharitis 10.2 EPO INS
49 postural hypotension 10.1
50 pancreatitis 10.1

Graphical network of the top 20 diseases related to Autonomic Neuropathy:



Diseases related to Autonomic Neuropathy

Symptoms & Phenotypes for Autonomic Neuropathy

MGI Mouse Phenotypes related to Autonomic Neuropathy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.07 AKR1B1 CCK ELP1 INS NGF NPY
2 homeostasis/metabolism MP:0005376 10.02 AKR1B1 ALB CCK ELP1 EPO INS
3 integument MP:0010771 9.8 RETREG1 SCN11A ELP1 EPO INS NGF
4 muscle MP:0005369 9.7 ALB ELP1 EPO INS NGF NTRK1
5 nervous system MP:0003631 9.65 CCK ELP1 INS NGF NPY NTRK1
6 renal/urinary system MP:0005367 9.1 AKR1B1 ALB ELP1 INS NPY WNK1

Drugs & Therapeutics for Autonomic Neuropathy

Drugs for Autonomic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 149)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
2
Midodrine Approved Phase 4 133163-28-7, 42794-76-3 4195
3
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 2 148553-50-8 5486971
4
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
5
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 2 23651-95-8 443940
6
Vildagliptin Approved, Investigational Phase 4,Phase 2 274901-16-5 6918537
7
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
8
Donepezil Approved Phase 4 120014-06-4 3152
9
Norepinephrine Approved Phase 4,Phase 2 51-41-2 439260
10
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
12
gamma-Aminobutyric acid Investigational Phase 4 56-12-2 119
13 Adjuvants, Immunologic Phase 4
14 Benphothiamine Phase 4
15 Chelating Agents Phase 4
16 HIV Protease Inhibitors Phase 4,Phase 2
17
protease inhibitors Phase 4,Phase 2
18 Hormone Antagonists Phase 4,Phase 2
19 Hormones Phase 4,Phase 2
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
21 Dipeptidyl-Peptidase IV Inhibitors Phase 4,Phase 2
22 Hypoglycemic Agents Phase 4,Phase 3,Phase 2
23 Antioxidants Phase 4,Phase 3,Phase 1
24 Micronutrients Phase 4,Phase 3
25 Protective Agents Phase 4,Phase 3,Phase 1
26 Thioctic Acid Phase 4
27 Trace Elements Phase 4,Phase 3
28 Vitamin B Complex Phase 4,Phase 3
29 Vitamins Phase 4,Phase 3
30 Angiotensin-Converting Enzyme Inhibitors Phase 4
31 Antihypertensive Agents Phase 4
32 Adrenergic Agents Phase 4,Phase 3,Phase 2
33 Adrenergic Agonists Phase 4,Phase 3,Phase 2
34 Adrenergic alpha-Agonists Phase 4,Phase 2
35 Autonomic Agents Phase 4,Phase 3,Phase 2
36 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Early Phase 1
37 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
38 Vasoconstrictor Agents Phase 4,Phase 2
39 Analgesics Phase 4,Phase 2,Phase 3
40 Anti-Anxiety Agents Phase 4,Phase 2
41 Anticonvulsants Phase 4,Phase 3,Phase 2
42 calcium channel blockers Phase 4,Phase 2
43 Calcium, Dietary Phase 4,Phase 2
44 Central Nervous System Depressants Phase 4,Phase 2
45 Psychotropic Drugs Phase 4,Phase 2
46 Tranquilizing Agents Phase 4,Phase 2
47 Antiparkinson Agents Phase 4,Phase 3,Phase 2
48 Dopamine Agents Phase 4,Phase 3,Phase 2
49 Cholinergic Agents Phase 4,Phase 3,Early Phase 1
50 Cholinesterase Inhibitors Phase 4,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 106)

id Name Status NCT ID Phase Drugs
1 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
2 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4 Benfotiamine;Placebo
3 Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy Unknown status NCT00123136 Phase 4
4 The Effect of α-lipoic Acid Treatment in Patient With Cardiac Autonomic Neuropathy Completed NCT02056366 Phase 4 α-lipoic acid
5 Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus Completed NCT03031834 Phase 4 Quinapril
6 Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study Completed NCT00466778 Phase 4
7 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4 Midodrine Hydrochloride
8 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy Completed NCT00573261 Phase 4 Pregabalin;Placebo
9 Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects Recruiting NCT02682901 Phase 4 Cycloset;Placebo
10 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4 Droxidopa capsules;Placebo capsules
11 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4 vildagliptin;Dapagliflozin
12 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4 midodrine hydrochloride (ProAmatine®)
13 Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy Terminated NCT00619983 Phase 4 donepezil;duloxetine;donepezil 2.5 mg and duloxetine 30mg;placebo;gabapentin
14 Pioglitazone in Impaired Glucose Tolerance Withdrawn NCT00306826 Phase 4 pioglitazone;simvastatin;pioglitazone + simvastatin
15 Fluid Retention in Rosiglitazone Treated Subjects With Autonomic Neuropathy. Completed NCT00422955 Phase 3 rosiglitazone
16 An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes Completed NCT00116207 Phase 3 ORAL ANTIOXIDANT
17 Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT) Completed NCT00594152 Phase 3 CIIIT
18 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3 Carbidopa;Placebo
19 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3 Droxidopa;Placebo
20 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3 Double blinded IVIg
21 The Effect of Diflunisal on Familial Amyloidosis Completed NCT00294671 Phase 2, Phase 3 diflunisal
22 A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa Completed NCT00782340 Phase 3 Placebo;Droxidopa
23 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00633880 Phase 3 Placebo;Droxidopa
24 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304) Completed NCT01132326 Phase 3 Droxidopa
25 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
26 Clinical Study on Acetyl-L-Carnitine Completed NCT01526564 Phase 3 Acetylcarnitine;Placebo
27 Effect of Autonomic Neuropathy on the Efficacy of a DPP-IV Inhibitor (Galvus) Therapy Completed NCT01452113 Phase 2 Vildagliptin
28 L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 Completed NCT01733407 Phase 1, Phase 2 L-serine;placebo
29 Efficacy and Safety of TAK-583 in Subjects With Diabetic Peripheral Neuropathy Completed NCT00760955 Phase 2 TAK-583;TAK-583;TAK-583;Placebo
30 A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain Completed NCT01345045 Phase 2 ABT-639;pregabalin;Placebo
31 Effects of Reiki on Painful Neuropathy and Cardiovascular Risk Factors Completed NCT00010751 Phase 2
32 Carbidopa for the Treatment of Excessive Blood Pressure Variability Recruiting NCT02553265 Phase 2 Carbidopa Low Dose;Carbidopa High Dose
33 The Safety, Tolerability and Efficacy of Dronabinol, for the Treatment of Nausea and Vomiting in Familial Dysautonomia Recruiting NCT02608931 Phase 2 Dronabinol
34 The Safety and Tolerability of Kinetin, in Patients With Familial Dysautonomia Recruiting NCT02274051 Phase 2
35 The Efficacy Of Intravenous Immunoglobulin Therapy In Treatment Induced Neuropathy Of Diabetes Recruiting NCT02915263 Phase 2 IGIV-C;0.9% Sodium Chloride
36 Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis Recruiting NCT01557296 Phase 2
37 The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia Recruiting NCT02276716 Phase 2 Phosphatidylserine
38 A Study of Effectiveness and Safety of JNJ-42160443 in Patients With Diabetic Painful Neuropathy Terminated NCT00993018 Phase 2 JNJ-42160443 (1 mg);JNJ-42160443 (3 mg);JNJ-42160443 (10 mg);Placebo
39 A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and Anhidrosis Withdrawn NCT02624310 Phase 2 Droxidopa (L-DOPS);Placebo
40 Cardiac Autonomic Neuropathy in Patients With Metabolic Syndrome Completed NCT00907127 Phase 1
41 N-acetylcysteine Given IV With Cisplatin and Paclitaxel in Patients With Ovarian Cancer Withdrawn NCT01138137 Phase 1 Paclitaxel;N-acetylcysteine;Cisplatin
42 The Relationship Between Vascular Adhesion Protein-1 and Diabetic Cardiovascular Autonomic Neuropathy Unknown status NCT01706289
43 A Comparison Between Pupillometry, Heart Rate Variability and Metaiodobenzylguanidine Scintigraphy for the Diagnosis of Early Diabetic Autonomic Neuropathy in Type 1 Diabetes Unknown status NCT01822431
44 Effect of DPP-IV Inhibitor on Glycemic Control and Autonomic Neuropathy in Adult Patients With Diabetes Mellitus Unknown status NCT01545024 Sitagliptin, 50 mg once per day per os
45 Sleep Apnea in Type 1 Diabetes Unknown status NCT01935765 Early Phase 1
46 Acute Effects of Inspiratory Muscle Exercise on Glucose Level and Glucose Variability in Patients With Type 2 Diabetes. Unknown status NCT02292810
47 Functional Electrical Stimulation in Chronic Kidney Disease Unknown status NCT02336776
48 Small-fiber Neuropathy in Chronic Kidney Disease Unknown status NCT01078857
49 Risk Analysis for Cardiovascular Autonomic Neuropathy Completed NCT02462616
50 Genetic, Environment and Its Interaction Analysis for Cardiovascular Autonomic Neuropathy Completed NCT02461342

Search NIH Clinical Center for Autonomic Neuropathy

Genetic Tests for Autonomic Neuropathy

Anatomical Context for Autonomic Neuropathy

MalaCards organs/tissues related to Autonomic Neuropathy:

39
Heart, Testes, Kidney, Spinal Cord, Brain, Skin, Endothelial

Publications for Autonomic Neuropathy

Articles related to Autonomic Neuropathy:

(show top 50) (show all 890)
id Title Authors Year
1
Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p.Gly87Arg variant in a Bangladeshi patient: a case report. ( 28802308 )
2017
2
Autoimmunity, Autonomic Neuropathy, and the HPV Vaccination: A Vulnerable Subpopulation. ( 28868890 )
2017
3
Continuous glucose monitoring adds information beyond HbA1c in well-controlled diabetes patients with early cardiovascular autonomic neuropathy. ( 28728915 )
2017
4
Autonomic Neuropathy and Albuminocytologic Dissociation in Cerebrospinal Fluid As the Presenting Features of Primary Amyloidosis: A Case Report. ( 28798722 )
2017
5
Prevalence of Autonomic Neuropathy in Patients of Rheumatoid Arthritis and Its Correlation with Disease Severity. ( 28571182 )
2017
6
Permutation entropy analysis of heart rate variability for the assessment of cardiovascular autonomic neuropathy in type 1 diabetes mellitus. ( 28527351 )
2017
7
Structured lifestyle intervention in patients with the metabolic syndrome mitigates oxidative stress but fails to improve measures of cardiovascular autonomic neuropathy. ( 28709739 )
2017
8
Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation. ( 28766925 )
2017
9
Effect of ramipril/hydrochlorothiazide and ramipril/canrenone combination on atrial fibrillation recurrence in hypertensive type 2 diabetic patients with and without cardiac autonomic neuropathy. ( 28507568 )
2017
10
The Preferential Impairment of Pupil Constriction Stimulated by Blue Light in Patients with Type 2 Diabetes without Autonomic Neuropathy. ( 28421205 )
2017
11
Managing supine hypertension in a patient with non-diabetic autonomic neuropathy receiving droxidopa for neurogenic orthostatic hypotension. ( 28623420 )
2017
12
Oral manifestations, dental management, and a rare homozygous mutation of the PRDM12 gene in a boy with hereditary sensory and autonomic neuropathy type VIII: a case report and review of the literature. ( 28807049 )
2017
13
A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV). ( 27676246 )
2017
14
Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia. ( 28928996 )
2017
15
Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes. ( 28638827 )
2017
16
Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series. ( 28841844 )
2017
17
Editorial: Limited Utility of the Handgrip Test for the Diagnosis of Diabetic Cardiovascular Autonomic Neuropathy: "There's Time Enough, But None to Spare". ( 27781938 )
2017
18
Cardiovascular Autonomic Neuropathy and Cardiovascular Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. ( 27803120 )
2017
19
Systemic Amyloidosis and Cardiac Autonomic Neuropathy Associated with Waldenstrom's Macroglobulinemia. ( 28695027 )
2017
20
Cardiac Autonomic Neuropathy in Patients with Type 2 Diabetes Mellitus at High Risk for Foot Ulcers. ( 28459026 )
2017
21
Potential Association of Triglyceride Glucose Index with Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus Patients. ( 28581270 )
2017
22
Effects of High-Dose I+-Lipoic Acid on Heart Rate Variability of Type 2 Diabetes Mellitus Patients with Cardiac Autonomic Neuropathy in Korea. ( 28868825 )
2017
23
WNK1/HSN2 founder mutation in patients with hereditary sensory and autonomic neuropathy: A Japanese cohort study. ( 28422281 )
2017
24
Prediction of autonomic neuropathy in chronic kidney disease (stage 5) Iraqi patients (case control study). ( 28757390 )
2017
25
Autonomic Neuropathy and Endothelial Dysfunction in Patients With Impaired Glucose Tolerance or Type 2 Diabetes Mellitus. ( 27057914 )
2016
26
Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes. ( 27741306 )
2016
27
Disease-modifying antirheumatic drugs improve cardiovascular autonomic neuropathy in psoriatic arthritis. ( 27047572 )
2016
28
[OP.1A.04] 24H AMBULATORY BLOOD PRESSURE MONITORING PROFILE IN PARKINSON'S DISEASE WITH AUTONOMIC NEUROPATHY. ( 27508622 )
2016
29
Cardiovascular autonomic neuropathy. ( 27034552 )
2016
30
Study of cardiac autonomic neuropathy and its association with QTc dispersion in patients with type-2 diabetes mellitus. ( 27727597 )
2016
31
Sacral nerve stimulation for fecal incontinence in a patient with anti-phospholipid syndrome-related autonomic neuropathy. ( 26670782 )
2016
32
A novel DNMT1 mutation associated with early onset hereditary sensory and autonomic neuropathy, cataplexy, cerebellar atrophy, scleroderma, endocrinopathy, and common variable immune deficiency. ( 27277422 )
2016
33
A study for association and interaction analysis to metabolic syndrome and the ESR1 gene on cardiovascular autonomic neuropathy in a Chinese Han population. ( 27453734 )
2016
34
Glycemic variability is an important risk factor for cardiovascular autonomic neuropathy in newly diagnosed type 2 diabetic patients. ( 27128543 )
2016
35
The influence of cardiovascular autonomic neuropathy on mortality in type 1 diabetic patients; 10-year follow-up. ( 26740046 )
2016
36
Arthropathy-related pain in a patient with congenital impairment of pain sensation due to hereditary sensory and autonomic neuropathy type II with a rare mutation in the WNK1/HSN2 gene: a case report. ( 27765018 )
2016
37
Corrigendum to: Porojan M., Costin S., Poanta L., Cerghizan A., Pop D., Dumitrascu D.L., Autonomic Neuropathy and Plasma Catecholamine in patients with Diabetes Mellitus. ( 27658170 )
2016
38
Assessment of the cardiac autonomic neuropathy among the known diabetics and age-matched controls using noninvasive cardiovascular reflex tests in a South-Indian population: A case-control study. ( 27390670 )
2016
39
Cardiovascular autonomic neuropathy in type 2 diabetes mellitus - A cross-sectional study. ( 27727611 )
2016
40
Poster 72 Teetering on the Edge: Rehabilitation in a Medically Complex Patient with Familial Dysautonomia (Hereditary Sensory Autonomic Neuropathy Type III): A Case Report. ( 27672840 )
2016
41
Hereditary Sensory and Autonomic Neuropathy Type IV in 9 Year Old Boy: A Case Report. ( 27247588 )
2016
42
Chronic alcoholics retain dyspeptic symptoms, pan-enteric dysmotility, and autonomic neuropathy before and after abstinence. ( 27684550 )
2016
43
Analysis of the association between glucose profiles and I^-cell function for diabetic cardiovascular autonomic neuropathy in China. ( 27736036 )
2016
44
Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes. ( 27352953 )
2016
45
Post-ganglionic autonomic neuropathy associated with anti-glutamic acid decarboxylase antibodies. ( 27913968 )
2016
46
Gastrointestinal autonomic neuropathy in diabetes: the unattended borderline between diabetology and gastroenterology. ( 26638001 )
2016
47
The analysis of blood pressure profiles and their severity in relation to diabetic cardiovascular autonomic neuropathy in the Chinese population: preliminary analysis. ( 26940214 )
2016
48
High and low vitamin D level is associated with cardiovascular autonomic neuropathy in people with Type 1 and Type 2 diabetes. ( 27696502 )
2016
49
Alternative Quantitative Tools in the Assessment of Diabetic Peripheral and Autonomic Neuropathy. ( 27133153 )
2016
50
Cardiovascular autonomic neuropathy in patients with diabetes mellitus. ( 27544842 )
2016

Variations for Autonomic Neuropathy

Expression for Autonomic Neuropathy

Search GEO for disease gene expression data for Autonomic Neuropathy.

Pathways for Autonomic Neuropathy

Pathways related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.77 NGF NPY NTRK1 SCN11A
2
Show member pathways
9.66 NGF NTRK1

GO Terms for Autonomic Neuropathy

Cellular components related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.8 CCK DST NTRK1

Biological processes related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to electrical stimulus GO:0051602 9.37 EPO NTRK1
2 negative regulation of neuron apoptotic process GO:0043524 9.33 NGF NTRK1 RETREG1
3 response to axon injury GO:0048678 9.32 EPO NTRK1
4 regulation of sensory perception of pain GO:0051930 9.26 CCK SCN11A
5 neurotrophin TRK receptor signaling pathway GO:0048011 8.96 NGF NTRK1
6 positive regulation of Ras protein signal transduction GO:0046579 8.8 EPO NGF NTRK1

Molecular functions related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuropeptide hormone activity GO:0005184 9.16 CCK NPY
2 protein kinase activator activity GO:0030295 8.96 EPO WNK1
3 hormone activity GO:0005179 8.92 CCK EPO INS NPY

Sources for Autonomic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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