MCID: ATN004
MIFTS: 45

Autonomic Neuropathy malady

Categories: Neuronal diseases

Aliases & Classifications for Autonomic Neuropathy

Aliases & Descriptions for Autonomic Neuropathy:

Name: Autonomic Neuropathy 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11504
NCIt 47 C27033
SNOMED-CT 64 277879009
UMLS 69 C0259749

Summaries for Autonomic Neuropathy

MalaCards based summary : Autonomic Neuropathy is related to dyspepsia and calcinosis. An important gene associated with Autonomic Neuropathy is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Brain-Derived Neurotrophic Factor (BDNF) signaling pathway and Neurotrophic factor-mediated Trk receptor signaling. The drugs Nabilone and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 71 Autonomic neuropathy (also AN or AAN) is a form of polyneuropathy that affects the non-voluntary,... more...

Related Diseases for Autonomic Neuropathy

Diseases related to Autonomic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
id Related Disease Score Top Affiliating Genes
1 dyspepsia 29.4 CCK NPY
2 calcinosis 29.3 ALB EPO INS
3 diabetic autonomic neuropathy 12.2
4 hereditary sensory and autonomic neuropathy type 1e 12.1
5 idiopathic peripheral autonomic neuropathy 12.1
6 hereditary sensory and autonomic neuropathy type iic 11.9
7 hereditary sensory and autonomic neuropathy with deafness and global delay 11.8
8 x-linked hereditary sensory and autonomic neuropathy with deafness 11.8
9 neuropathy, hereditary sensory and autonomic, type ii 11.8
10 neuropathy, hereditary sensory and autonomic, type v 11.8
11 dysautonomia, familial 11.8
12 insensitivity to pain, congenital, with anhidrosis 11.8
13 neuropathy, hereditary sensory and autonomic, type vii 11.7
14 neuropathy, hereditary sensory, type ie 11.7
15 neuropathy, hereditary sensory and autonomic, type vi 11.7
16 hereditary sensory neuropathy 11.6
17 neuropathy, hereditary sensory and autonomic, type ia 11.6
18 neuropathy, hereditary sensory and autonomic, type viii 11.6
19 neuropathy, hereditary sensory and autonomic, type iib 11.6
20 neuropathy, hereditary sensory, type ib 11.6
21 neuropathy, hereditary sensory and autonomic, type ic 11.5
22 dysautonomia 11.2
23 diabetic neuropathy 11.1
24 autonomic dysfunction 11.1
25 autoimmune gastrointestinal dysmotility 11.0
26 neuropathy 11.0
27 congenital insensitivity to pain-hypohidrosis syndrome 11.0
28 sensory peripheral neuropathy 11.0
29 dnmt1-related dementia, deafness, and sensory neuropathy 10.8
30 autoimmune autonomic ganglionopathy 10.8
31 deafness, x-linked 5 10.8
32 neuropathy, hereditary sensory, with spastic paraplegia 10.8
33 prp systemic amyloidosis 10.8
34 hereditary neuropathies 10.8
35 lipomatosis, multiple symmetric 10.8
36 familial syringomyelia 10.8
37 gall bladder carcinoma in situ 10.3 NGF NTRK1
38 familial spastic paralysis 10.2 ELP1 NGF
39 hypertrophic osteoarthropathy, primary, autosomal recessive 2 10.2 NTRK1 SPTLC1
40 cerebral atrophy 10.2 SPTLC1 WNK1
41 lung occult small cell carcinoma 10.2 NGF NTRK1
42 extratemporal epilepsy 10.2 INS SPTLC1
43 postural hypotension 10.1
44 breast fibroadenoma 10.1 INS NTF3
45 c5 deficiency 10.1 ELP1 NGF
46 senile angioma 10.1 NGF NTF3 SPTLC1
47 dacryoadenitis 10.1 EPO INS
48 submucous uterine fibroid 10.1 ALB INS
49 pancreatitis 10.1
50 mucopolysaccharidosis 10.1 AKR1B1 NGF NTF3

Graphical network of the top 20 diseases related to Autonomic Neuropathy:



Diseases related to Autonomic Neuropathy

Symptoms & Phenotypes for Autonomic Neuropathy

MGI Mouse Phenotypes related to Autonomic Neuropathy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.2 NTRK1 RETREG1 SPTLC1 AKR1B1 CCK ELP1
2 homeostasis/metabolism MP:0005376 10.14 NPY NTF3 SPTLC1 WNK1 AKR1B1 ALB
3 growth/size/body region MP:0005378 10.09 AKR1B1 ELP1 INS KIF1A NGF NPY
4 mortality/aging MP:0010768 10.06 AKR1B1 ALB ELP1 EPO INS KIF1A
5 integument MP:0010771 9.91 ELP1 EPO INS KIF1A NGF NTRK1
6 nervous system MP:0003631 9.9 CCK ELP1 INS KIF1A NGF NPY
7 muscle MP:0005369 9.86 ALB ELP1 EPO INS NGF NTF3
8 normal MP:0002873 9.5 ALB EPO INS NGF NPY NTF3
9 renal/urinary system MP:0005367 9.1 AKR1B1 ALB ELP1 INS NPY WNK1

Drugs & Therapeutics for Autonomic Neuropathy

Drugs for Autonomic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 334)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nabilone Approved, Investigational Phase 4,Phase 3 51022-71-0 5284592
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 137-58-6 3676
3
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
4
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
5
Ephedrine Approved Phase 4,Phase 1 299-42-3 9294
6
Pseudoephedrine Approved Phase 4,Phase 1 90-82-4 7028
7
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
8
Midodrine Approved Phase 4 133163-28-7, 42794-76-3 4195
9
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2 148553-50-8 5486971
10
Cilostazol Approved Phase 4 73963-72-1 2754
11
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
12
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
13
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
14
Propranolol Approved, Investigational Phase 4 525-66-6 4946
15
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
16
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
17
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 23651-95-8 443940
18
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
19
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
21
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
22 Adjuvants, Immunologic Phase 4
23 Benphothiamine Phase 4
24 Chelating Agents Phase 4
25 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1
26 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1
28 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1
29 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
30
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
31 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
32 Adrenergic Agonists Phase 4,Phase 3,Phase 2
33 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
34 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Vasoconstrictor Agents Phase 4,Phase 2,Phase 1
38 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
39 Anti-Anxiety Agents Phase 4,Phase 3,Phase 2
40 Anticonvulsants Phase 4,Phase 3,Phase 2
41 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
42 Psychotropic Drugs Phase 4,Phase 3,Phase 2
43 Tranquilizing Agents Phase 4,Phase 3,Phase 2
44 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
45 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Bronchodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Fibrinolytic Agents Phase 4,Phase 1
49 Neuroprotective Agents Phase 4,Phase 3,Phase 2,Phase 1
50 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 208)
id Name Status NCT ID Phase
1 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
2 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4
3 Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy Unknown status NCT00123136 Phase 4
4 The Effect of α-lipoic Acid Treatment in Patient With Cardiac Autonomic Neuropathy Completed NCT02056366 Phase 4
5 Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus Completed NCT03031834 Phase 4
6 Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study Completed NCT00466778 Phase 4
7 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4
8 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy Completed NCT00573261 Phase 4
9 Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Diabetic Peripheral Neuropathy Completed NCT00380913 Phase 4
10 Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Chemotherapy-Induced Neuropathy Completed NCT00380965 Phase 4
11 Asian Study on Cilostazol Effectivity in Neuropathies of Diabetes Mellitus Type 2-A Pilot Study in the Philippines Completed NCT01076478 Phase 4
12 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4
13 Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study) Completed NCT01458600 Phase 4
14 Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome Completed NCT02140632 Phase 4
15 Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica Completed NCT01816334 Phase 4
16 Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects Recruiting NCT02682901 Phase 4
17 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4
18 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4
19 Preoperative Brimonidine on IOP of Patients Undergoing RALP Recruiting NCT02818816 Phase 4
20 Injection Versus Splinting in Carpal Tunnel Syndrome Active, not recruiting NCT02038452 Phase 4
21 Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome Enrolling by invitation NCT02652390 Phase 4
22 Combined Radiotherapy and Intravenous Steroids for Early Progressive Thyroid Eye Disease Not yet recruiting NCT02339142 Phase 4
23 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4
24 Pioglitazone in Impaired Glucose Tolerance Withdrawn NCT00306826 Phase 4
25 Efficacy Study of Nabilone in the Treatment of Diabetic Peripheral Neuropathic Pain Unknown status NCT01035281 Phase 3
26 Outcomes of Steroid and Oxygen Therapy Versus Placebo Therapy in Non-arteritic Anterior Ischemic Optic Neuropathy Unknown status NCT02439866 Phase 3
27 Diabetic Neuropathy Topical Treatment Unknown status NCT00661063 Phase 3
28 Fluid Retention in Rosiglitazone Treated Subjects With Autonomic Neuropathy. Completed NCT00422955 Phase 3
29 An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes Completed NCT00116207 Phase 3
30 Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT) Completed NCT00594152 Phase 3
31 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3
32 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3
33 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3
34 The Effect of Diflunisal on Familial Amyloidosis Completed NCT00294671 Phase 2, Phase 3
35 A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa Completed NCT00782340 Phase 3
36 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00633880 Phase 3
37 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304) Completed NCT01132326 Phase 3
38 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3
39 Clinical Study on Acetyl-L-Carnitine Completed NCT01526564 Phase 3
40 Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis Completed NCT00409175 Phase 2, Phase 3
41 The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury Completed NCT02099890 Phase 3
42 Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN) Completed NCT01474772 Phase 3
43 Effect Of Pregabalin Treatment In Patients With Diabetic Nerve Pain Who Currently Use A Non-Steroid Anti-Inflammatory Drug (NSAID) For Another Pain Completed NCT01455415 Phase 3
44 Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer Completed NCT00516503 Phase 3
45 Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy Completed NCT01099449 Phase 3
46 A Multicentre, Single-arm, Open-label Safety Study of Lenalidomide Plus Dexamethasone in Previously Treated Subjects With Multiple Myeloma Completed NCT00420849 Phase 3
47 Efficacy and Safety Study of 3 Thalidomide Doses for the Treatment of Relapsed Refractory Multiple Myeloma Completed NCT00452569 Phase 3
48 A Randomised Evaluation of Molecular Guided Therapy for Diffuse Large B-cell Lymphoma With Bortezomib Completed NCT01324596 Phase 3
49 Steroid Injection Treatment of Carpal Tunnel Syndrome Completed NCT00806871 Phase 2, Phase 3
50 Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON Completed NCT00428727 Phase 3

Search NIH Clinical Center for Autonomic Neuropathy

Genetic Tests for Autonomic Neuropathy

Anatomical Context for Autonomic Neuropathy

MalaCards organs/tissues related to Autonomic Neuropathy:

39
Heart, Testes, Brain, Spinal Cord, Skin, Kidney, Liver

Publications for Autonomic Neuropathy

Articles related to Autonomic Neuropathy:

(show top 50) (show all 868)
id Title Authors Year
1
A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV). ( 27676246 )
2017
2
Editorial: Limited Utility of the Handgrip Test for the Diagnosis of Diabetic Cardiovascular Autonomic Neuropathy: "There's Time Enough, But None to Spare". ( 27781938 )
2017
3
Cardiovascular Autonomic Neuropathy and Cardiovascular Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. ( 27803120 )
2017
4
Corrigendum to: Porojan M., Costin S., Poanta L., Cerghizan A., Pop D., Dumitrascu D.L., Autonomic Neuropathy and Plasma Catecholamine in patients with Diabetes Mellitus. ( 27658170 )
2016
5
Pediatric Anti-ganglionic AntibodyA Positive Autonomic Neuropathy: Clinical Presentation and Response to Treatment. ( 27569256 )
2016
6
Cardiovascular autonomic neuropathy. ( 27034552 )
2016
7
Alternative Quantitative Tools in the Assessment of Diabetic Peripheral and Autonomic Neuropathy. ( 27133153 )
2016
8
Study of cardiac autonomic neuropathy and its association with QTc dispersion in patients with type-2 diabetes mellitus. ( 27727597 )
2016
9
Glycemic variability is an important risk factor for cardiovascular autonomic neuropathy in newly diagnosed type 2 diabetic patients. ( 27128543 )
2016
10
Poster 72 Teetering on the Edge: Rehabilitation in a Medically Complex Patient with Familial Dysautonomia (Hereditary Sensory Autonomic Neuropathy Type III): A Case Report. ( 27672840 )
2016
11
Cardiovascular autonomic neuropathy in patients with diabetes mellitus. ( 27544842 )
2016
12
The analysis of blood pressure profiles and their severity in relation to diabetic cardiovascular autonomic neuropathy in the Chinese population: preliminary analysis. ( 26940214 )
2016
13
Orthopaedic manifestations of congenital indifference to pain with anhidrosis (Hereditary Sensory and Autonomic Neuropathy type IV). ( 27637569 )
2016
14
High and low vitamin D level is associated with cardiovascular autonomic neuropathy in people with Type 1 and Type 2 diabetes. ( 27696502 )
2016
15
Sacral nerve stimulation for fecal incontinence in a patient with anti-phospholipid syndrome-related autonomic neuropathy. ( 26670782 )
2016
16
Autonomic Neuropathy and Endothelial Dysfunction in Patients With Impaired Glucose Tolerance or Type 2 Diabetes Mellitus. ( 27057914 )
2016
17
Post-ganglionic autonomic neuropathy associated with anti-glutamic acid decarboxylase antibodies. ( 27913968 )
2016
18
A study for association and interaction analysis to metabolic syndrome and the ESR1 gene on cardiovascular autonomic neuropathy in a Chinese Han population. ( 27453734 )
2016
19
Chronic alcoholics retain dyspeptic symptoms, pan-enteric dysmotility, and autonomic neuropathy before and after abstinence. ( 27684550 )
2016
20
To study the prevalence of cardiac autonomic neuropathy in patients with type 2 diabetes with diabetic foot. ( 27728140 )
2016
21
An association analysis of lipid profile and diabetic cardiovascular autonomic neuropathy in a Chinese sample. ( 27457375 )
2016
22
Analysis of the association between glucose profiles and I^-cell function for diabetic cardiovascular autonomic neuropathy in China. ( 27736036 )
2016
23
Silent myocardial infarction secondary to cardiac autonomic neuropathy in a patient with rheumatoid arthritis. ( 27489064 )
2016
24
The influence of cardiovascular autonomic neuropathy on mortality in type 1 diabetic patients; 10-year follow-up. ( 26740046 )
2016
25
Hereditary Sensory and Autonomic Neuropathy Type IV in 9 Year Old Boy: A Case Report. ( 27247588 )
2016
26
Cardiovascular autonomic neuropathy in type 2 diabetes mellitus - A cross-sectional study. ( 27727611 )
2016
27
Diabetic Retinopathy Is Strongly Predictive of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes. ( 26955641 )
2016
28
Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes. ( 27352953 )
2016
29
Nocturnal antihypertensive treatment in patients with type 1 diabetes with autonomic neuropathy and non-dipping: a randomised, placebo-controlled, double-blind cross-over trial. ( 27920083 )
2016
30
Predictors of autonomic neuropathy in rheumatoid arthritis. ( 27503343 )
2016
31
Cardiovascular autonomic neuropathy associates with nephropathy lesions in American Indians with type 2 diabetes. ( 27041674 )
2016
32
Cardiac autonomic neuropathy risk estimated by sudomotor function and arterial stiffness in Chinese subjects. ( 26740338 )
2016
33
Arthropathy-related pain in a patient with congenital impairment of pain sensation due to hereditary sensory and autonomic neuropathy type II with a rare mutation in the WNK1/HSN2 gene: a case report. ( 27765018 )
2016
34
Neuronal intranuclear inclusion disease with leukoencephalopathy and light motor-sensory and autonomic neuropathy diagnosed by skin biopsy. ( 27538646 )
2016
35
QTc prolongation in patients of diabetes mellitus as an indicator of cardiac autonomic neuropathy (CAN). ( 27727543 )
2016
36
Use of corrected QT interval prolongation as diagnostic tool for assessment of cardiac autonomic neuropathy in diabetic patients. ( 27727623 )
2016
37
Disease-modifying antirheumatic drugs improve cardiovascular autonomic neuropathy in psoriatic arthritis. ( 27047572 )
2016
38
Risk factors of diabetic cardiac autonomic neuropathy in patients with type 1 diabetes mellitus: a meta-analysis. ( 27843562 )
2016
39
Why not to use the handgrip test in the assessment of cardiovascular autonomic neuropathy among patients with diabetes mellitus? ( 27550055 )
2016
40
Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes. ( 27638143 )
2016
41
Assessment of the cardiac autonomic neuropathy among the known diabetics and age-matched controls using noninvasive cardiovascular reflex tests in a South-Indian population: A case-control study. ( 27390670 )
2016
42
Validation of the Composite Autonomic Symptom Score 31 (COMPASS 31) for the assessment of symptoms of autonomic neuropathy in people with diabetes. ( 27990686 )
2016
43
[OP.1A.04] 24H AMBULATORY BLOOD PRESSURE MONITORING PROFILE IN PARKINSON'S DISEASE WITH AUTONOMIC NEUROPATHY. ( 27508622 )
2016
44
Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes. ( 27741306 )
2016
45
Association and interaction analysis of diabetes mellitus and SCN10A for cardiovascular autonomic neuropathy in a Chinese population. ( 27729462 )
2016
46
A novel DNMT1 mutation associated with early onset hereditary sensory and autonomic neuropathy, cataplexy, cerebellar atrophy, scleroderma, endocrinopathy, and common variable immune deficiency. ( 27277422 )
2016
47
Gastrointestinal autonomic neuropathy in diabetes: the unattended borderline between diabetology and gastroenterology. ( 26638001 )
2016
48
Diabetes and cardiac autonomic neuropathy: Clinical manifestations, cardiovascular consequences, diagnosis and treatment. ( 25685280 )
2015
49
The puzzle of orthostatic tolerance in hereditary sensory and autonomic neuropathy, type IV. ( 25866260 )
2015
50
Inspiratory muscle training in patients with diabetic autonomic neuropathy: a randomized clinical trial. ( 25982993 )
2015

Variations for Autonomic Neuropathy

Expression for Autonomic Neuropathy

Search GEO for disease gene expression data for Autonomic Neuropathy.

Pathways for Autonomic Neuropathy

Pathways related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.49 NGF NTF3 NTRK1
2
Show member pathways
10.58 NGF NTF3 NTRK1
3
Show member pathways
10 NGF NTRK1

GO Terms for Autonomic Neuropathy

Cellular components related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 AKR1B1 ALB CCK EPO INS NPY

Biological processes related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

(show all 11)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell migration GO:0030335 9.67 ELP1 INS NTF3
2 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.54 NGF NTF3 NTRK1
3 response to axon injury GO:0048678 9.48 EPO NTRK1
4 response to electrical stimulus GO:0051602 9.46 EPO NTRK1
5 activation of protein kinase B activity GO:0032148 9.43 INS NTF3
6 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.43 CCK INS NTF3
7 regulation of neuron differentiation GO:0045664 9.4 NGF NTF3
8 microtubule-based movement GO:0007018 9.33 KIF1A NGF NTRK1
9 neurotrophin TRK receptor signaling pathway GO:0048011 9.32 NGF NTRK1
10 negative regulation of neuron apoptotic process GO:0043524 9.26 NGF NTF3 NTRK1 RETREG1
11 positive regulation of Ras protein signal transduction GO:0046579 8.8 EPO NGF NTRK1

Molecular functions related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuropeptide hormone activity GO:0005184 9.26 CCK NPY
2 protein kinase activator activity GO:0030295 9.16 EPO WNK1
3 neurotrophin p75 receptor binding GO:0005166 8.96 NTF3 NTRK1
4 hormone activity GO:0005179 8.92 CCK EPO INS NPY

Sources for Autonomic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....