MCID: ATN004
MIFTS: 46

Autonomic Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Autonomic Neuropathy

MalaCards integrated aliases for Autonomic Neuropathy:

Name: Autonomic Neuropathy 12 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11504
NCIt 46 C27033
SNOMED-CT 64 277879009
UMLS 69 C0259749

Summaries for Autonomic Neuropathy

MalaCards based summary : Autonomic Neuropathy is related to neuropathy, hereditary sensory and autonomic, type iii and neuropathy, hereditary sensory and autonomic, type iia. An important gene associated with Autonomic Neuropathy is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Neuroscience and Activation of TRKA receptors. The drugs Quinapril and Midodrine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and kidney, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 72 Autonomic neuropathy (also AN or AAN) is a form of polyneuropathy that affects the non-voluntary,... more...

Related Diseases for Autonomic Neuropathy

Diseases related to Autonomic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 205)
# Related Disease Score Top Affiliating Genes
1 neuropathy, hereditary sensory and autonomic, type iii 33.7 ELP1 NGF
2 neuropathy, hereditary sensory and autonomic, type iia 33.6 ELP1 RETREG1 WNK1
3 neuropathy, hereditary sensory and autonomic, type v 33.5 NGF NTRK1
4 diabetic autonomic neuropathy 33.0 AKR1B1 EPO INS NGF
5 hereditary sensory neuropathy 32.7 NGF NTRK1 RETREG1 SPTLC1 WNK1
6 dysautonomia 32.5 ELP1 NTRK1
7 autonomic dysfunction 32.2 RETREG1 SPTLC1 WNK1
8 neuropathy 31.1 ELP1 NGF RETREG1 SCN11A SPTLC1 WNK1
9 diabetic neuropathy 31.1 AKR1B1 EPO INS NGF NTRK1
10 autonomic nervous system disease 30.9 ALB INS NGF
11 diabetic polyneuropathy 30.2 AKR1B1 NGF
12 pheochromocytoma 29.2 NGF NPY NTRK1
13 chronic kidney failure 29.2 ALB EPO INS
14 microvascular complications of diabetes 5 29.1 AKR1B1 ALB INS
15 microvascular complications of diabetes 3 29.0 AKR1B1 ALB INS
16 uremia 28.8 ALB EPO INS
17 hereditary sensory and autonomic neuropathy type 1e 12.2
18 idiopathic peripheral autonomic neuropathy 12.2
19 insensitivity to pain, congenital, with anhidrosis 12.1
20 neuropathy, hereditary sensory and autonomic, type vii 12.0
21 neuropathy, hereditary sensory, type ie 12.0
22 x-linked hereditary sensory and autonomic neuropathy with deafness 12.0
23 hereditary sensory and autonomic neuropathy with deafness and global delay 12.0
24 neuropathy, hereditary sensory and autonomic, type viii 12.0
25 neuropathy, hereditary sensory and autonomic, type vi 11.7
26 neuropathy, hereditary sensory and autonomic, type ia 11.7
27 neuropathy, hereditary sensory and autonomic, type iib 11.7
28 neuropathy, hereditary sensory and autonomic, type i, with cough and gastroesophageal reflux 11.7
29 neuropathy, hereditary sensory and autonomic, type ic 11.5
30 autoimmune autonomic ganglionopathy 11.3
31 lipomatosis, multiple symmetric 11.2
32 sensory peripheral neuropathy 11.1
33 neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive 11.0
34 deafness, x-linked 5 11.0
35 dnmt1-related dementia, deafness, and sensory neuropathy 11.0
36 prp systemic amyloidosis 11.0
37 indifference to pain, congenital, autosomal recessive 10.9
38 autoimmune gastrointestinal dysmotility 10.9
39 ramos arroyo clark syndrome 10.9
40 hereditary neuropathies 10.9
41 diabetes mellitus 10.6
42 askin's tumor 10.5 NGF NTRK1
43 prolactin producing pituitary tumor 10.5 NGF NTRK1
44 conjunctival nevus 10.4 NGF NTRK1
45 jejunoileitis 10.4 ELP1 NGF
46 sweat gland disease 10.4 NGF NTRK1
47 paine syndrome 10.3 NGF SCN11A
48 inflammatory and toxic neuropathy 10.3 INS SPTLC1
49 postural hypotension 10.2
50 sheehan syndrome 10.1 EPO INS

Graphical network of the top 20 diseases related to Autonomic Neuropathy:



Diseases related to Autonomic Neuropathy

Symptoms & Phenotypes for Autonomic Neuropathy

MGI Mouse Phenotypes related to Autonomic Neuropathy:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.07 AKR1B1 CCK ELP1 INS NGF NPY
2 homeostasis/metabolism MP:0005376 10.02 ELP1 EPO INS NGF NPY SPTLC1
3 integument MP:0010771 9.8 ELP1 EPO INS NGF NTRK1 RETREG1
4 muscle MP:0005369 9.7 ALB ELP1 EPO INS NGF NTRK1
5 nervous system MP:0003631 9.65 RETREG1 SCN11A SPTLC1 WNK1 CCK ELP1
6 renal/urinary system MP:0005367 9.17 AKR1B1 ALB CCK ELP1 INS NPY

Drugs & Therapeutics for Autonomic Neuropathy

Drugs for Autonomic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 142)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
2
Midodrine Approved Phase 4 42794-76-3, 133163-28-7 4195
3
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
4
Droxidopa Approved, Investigational Phase 4,Phase 3,Phase 2 23651-95-8 443940
5
Vildagliptin Approved, Investigational Phase 4,Phase 2 274901-16-5 6918537
6
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
7
Donepezil Approved Phase 4 120014-06-4 3152
8
Norepinephrine Approved Phase 4,Phase 2 51-41-2 439260
9
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
10
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
12 Adjuvants, Immunologic Phase 4
13 Benphothiamine Phase 4
14 Chelating Agents Phase 4
15 HIV Protease Inhibitors Phase 4,Phase 2
16
protease inhibitors Phase 4,Phase 2
17 Hormone Antagonists Phase 4,Phase 2
18 Hormones Phase 4,Phase 2
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
20 Dipeptidyl-Peptidase IV Inhibitors Phase 4,Phase 2
21 Hypoglycemic Agents Phase 4,Phase 3,Phase 2
22 Antioxidants Phase 4,Phase 3,Phase 1
23 Micronutrients Phase 4,Phase 3
24 Protective Agents Phase 4,Phase 3,Phase 1
25 Thioctic Acid Phase 4
26 Trace Elements Phase 4,Phase 3
27 Vitamin B Complex Phase 4,Phase 3
28 Vitamins Phase 4,Phase 3
29 Angiotensin-Converting Enzyme Inhibitors Phase 4
30 Antihypertensive Agents Phase 4
31 Adrenergic Agents Phase 4,Phase 3,Phase 2
32 Adrenergic Agonists Phase 4,Phase 3,Phase 2
33 Adrenergic alpha-Agonists Phase 4,Phase 2
34 Autonomic Agents Phase 4,Phase 3,Phase 2
35 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Early Phase 1
36 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
37 Vasoconstrictor Agents Phase 4,Phase 2
38 Antiparkinson Agents Phase 4,Phase 3,Phase 2
39 Dopamine Agents Phase 4,Phase 3,Phase 2
40 Analgesics Phase 4,Phase 2,Phase 3
41 Anti-Anxiety Agents Phase 4,Phase 2
42 Anticonvulsants Phase 4,Phase 3,Phase 2
43 calcium channel blockers Phase 4,Phase 2
44 Calcium, Dietary Phase 4,Phase 2
45 Central Nervous System Depressants Phase 4,Phase 2
46 Cholinergic Agents Phase 4,Phase 3,Early Phase 1
47 Cholinesterase Inhibitors Phase 4,Early Phase 1
48 Psychotropic Drugs Phase 4,Phase 2
49 Tranquilizing Agents Phase 4,Phase 2
50 Antimetabolites Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 88)

# Name Status NCT ID Phase Drugs
1 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
2 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4 Benfotiamine;Placebo
3 The Effect of α-lipoic Acid Treatment in Patient With Cardiac Autonomic Neuropathy Completed NCT02056366 Phase 4 α-lipoic acid
4 Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus Completed NCT03031834 Phase 4 Quinapril
5 Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study Completed NCT00466778 Phase 4
6 A Study for Patients With Neurogenic Orthostatic Hypotension Completed NCT00046475 Phase 4 Midodrine Hydrochloride
7 Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects Recruiting NCT02682901 Phase 4 Cycloset;Placebo
8 Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Recruiting NCT02586623 Phase 4 Droxidopa capsules;Placebo capsules
9 Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor Recruiting NCT03178591 Phase 4 vildagliptin;Dapagliflozin
10 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4 midodrine hydrochloride (ProAmatine®)
11 Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy Terminated NCT00619983 Phase 4 donepezil;duloxetine;donepezil 2.5 mg and duloxetine 30mg;placebo;gabapentin
12 Pioglitazone in Impaired Glucose Tolerance Withdrawn NCT00306826 Phase 4 pioglitazone;simvastatin;pioglitazone + simvastatin
13 Fluid Retention in Rosiglitazone Treated Subjects With Autonomic Neuropathy. Completed NCT00422955 Phase 3 rosiglitazone
14 An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes Completed NCT00116207 Phase 3 ORAL ANTIOXIDANT
15 Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT) Completed NCT00594152 Phase 3 CIIIT
16 Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia Completed NCT01212484 Phase 3 Carbidopa;Placebo
17 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3 Droxidopa;Placebo
18 Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Completed NCT01522235 Phase 2, Phase 3 Double blinded IVIg
19 The Effect of Diflunisal on Familial Amyloidosis Completed NCT00294671 Phase 2, Phase 3 diflunisal
20 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
21 Effect of Autonomic Neuropathy on the Efficacy of a DPP-IV Inhibitor (Galvus) Therapy Completed NCT01452113 Phase 2 Vildagliptin
22 L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 Completed NCT01733407 Phase 1, Phase 2 L-serine;placebo
23 Efficacy and Safety of TAK-583 in Subjects With Diabetic Peripheral Neuropathy Completed NCT00760955 Phase 2 TAK-583;TAK-583;TAK-583;Placebo
24 A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain Completed NCT01345045 Phase 2 ABT-639;pregabalin;Placebo
25 Carbidopa for the Treatment of Excessive Blood Pressure Variability Recruiting NCT02553265 Phase 2 Carbidopa Low Dose;Carbidopa High Dose
26 The Safety, Tolerability and Efficacy of Dronabinol, for the Treatment of Nausea and Vomiting in Familial Dysautonomia Recruiting NCT02608931 Phase 2 Dronabinol
27 The Safety and Tolerability of Kinetin, in Patients With Familial Dysautonomia Recruiting NCT02274051 Phase 2
28 The Efficacy Of Intravenous Immunoglobulin Therapy In Treatment Induced Neuropathy Of Diabetes Recruiting NCT02915263 Phase 2 IGIV-C;0.9% Sodium Chloride
29 Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis Recruiting NCT01557296 Phase 2
30 The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia Recruiting NCT02276716 Phase 2 Phosphatidylserine
31 A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and Anhidrosis Withdrawn NCT02624310 Phase 2 Droxidopa (L-DOPS);Placebo
32 Cardiac Autonomic Neuropathy in Patients With Metabolic Syndrome Completed NCT00907127 Phase 1
33 N-acetylcysteine Given IV With Cisplatin and Paclitaxel in Patients With Ovarian Cancer Withdrawn NCT01138137 Phase 1 Paclitaxel;N-acetylcysteine;Cisplatin
34 The Relationship Between Vascular Adhesion Protein-1 and Diabetic Cardiovascular Autonomic Neuropathy Unknown status NCT01706289
35 A Comparison Between Pupillometry, Heart Rate Variability and Metaiodobenzylguanidine Scintigraphy for the Diagnosis of Early Diabetic Autonomic Neuropathy in Type 1 Diabetes Unknown status NCT01822431
36 Effect of DPP-IV Inhibitor on Glycemic Control and Autonomic Neuropathy in Adult Patients With Diabetes Mellitus Unknown status NCT01545024 Sitagliptin, 50 mg once per day per os
37 Sleep Apnea in Type 1 Diabetes Unknown status NCT01935765 Early Phase 1
38 Acute Effects of Inspiratory Muscle Exercise on Glucose Level and Glucose Variability in Patients With Type 2 Diabetes. Unknown status NCT02292810
39 Functional Electrical Stimulation in Chronic Kidney Disease Unknown status NCT02336776
40 Effects of Feet Mechanical Stimulation on Cardiovascular Autonomic Profile and Inflammation in Parkinson's Disease Unknown status NCT02608424
41 Small-fiber Neuropathy in Chronic Kidney Disease Unknown status NCT01078857
42 Risk Analysis for Cardiovascular Autonomic Neuropathy Completed NCT02462616
43 Genetic, Environment and Its Interaction Analysis for Cardiovascular Autonomic Neuropathy Completed NCT02461342
44 Bayesian Estimation of Diagnostic Performance for Cardiovascular Autonomic Neuropathy Completed NCT02459522
45 QUANtification of Cardiovascular Autonomic Neuropathy (CAN) and the Effects of Anaesthesia on Haemodynamics and Cerebral Perfusion Completed NCT03071432
46 The Relative Prevalence and Severity of Autonomic Nervous System Dysfunction Completed NCT00919347
47 Effects of Physical Training on Heart Rate Variability and Exercise Capacity in Diabetes With Autonomic Neuropathy Completed NCT00904761
48 Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients Completed NCT00953914 Pyridostigmine;Placebo
49 Coronary Blood Flow Regulation During General Anesthesia Completed NCT00866801
50 NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes Completed NCT01707979

Search NIH Clinical Center for Autonomic Neuropathy

Genetic Tests for Autonomic Neuropathy

Anatomical Context for Autonomic Neuropathy

MalaCards organs/tissues related to Autonomic Neuropathy:

38
Heart, Testes, Kidney, Spinal Cord, Brain, Skin, Endothelial

Publications for Autonomic Neuropathy

Articles related to Autonomic Neuropathy:

(show top 50) (show all 909)
# Title Authors Year
1
Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment. ( 29359025 )
2018
2
Seronegative autoimmune autonomic neuropathy: a distinct clinical entity. ( 29280036 )
2018
3
Cardiovascular autonomic neuropathy in adolescents and young adults with type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth Cohort Study. ( 29292558 )
2018
4
Autoimmune autonomic neuropathies: time to look beyond autoimmune autonomic ganglionopathy. ( 29305816 )
2018
5
Very High Frequency Oscillations of Heart Rate Variability in Healthy Humans and in Patients with Cardiovascular Autonomic Neuropathy. ( 29429029 )
2018
6
Oral manifestations, dental management, and a rare homozygous mutation of the PRDM12 gene in a boy with hereditary sensory and autonomic neuropathy type VIII: a case report and review of the literature. ( 28807049 )
2017
7
Effects of High-Dose I+-Lipoic Acid on Heart Rate Variability of Type 2 Diabetes Mellitus Patients with Cardiac Autonomic Neuropathy in Korea. ( 28868825 )
2017
8
Autoimmunity, Autonomic Neuropathy, and the HPV Vaccination: A Vulnerable Subpopulation. ( 28868890 )
2017
9
Clinical and metabolic consequences of L-serine supplementation in hereditary sensory and autonomic neuropathy type 1C. ( 29042446 )
2017
10
Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p.Gly87Arg variant in a Bangladeshi patient: a case report. ( 28802308 )
2017
11
Cardiac autonomic neuropathy may play a role in pathogenesis of atherosclerosis in type 1 diabetes mellitus. ( 28993155 )
2017
12
Response: Effects of High-Dose I+-Lipoic Acid on Heart Rate Variability of Type 2 Diabetes Mellitus Patients with Cardiac Autonomic Neuropathy in Korea (Diabetes Metab J 2017;41:275-83). ( 29086541 )
2017
13
Structured lifestyle intervention in patients with the metabolic syndrome mitigates oxidative stress but fails to improve measures of cardiovascular autonomic neuropathy. ( 28709739 )
2017
14
WNK1/HSN2 founder mutation in patients with hereditary sensory and autonomic neuropathy: A Japanese cohort study. ( 28422281 )
2017
15
Association of sleep apnoea syndrome and autonomic neuropathy in type 1 diabetes. ( 29169926 )
2017
16
Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation. ( 28766925 )
2017
17
Autonomic Neuropathy and Albuminocytologic Dissociation in Cerebrospinal Fluid As the Presenting Features of Primary Amyloidosis: A Case Report. ( 28798722 )
2017
18
The Preferential Impairment of Pupil Constriction Stimulated by Blue Light in Patients with Type 2 Diabetes without Autonomic Neuropathy. ( 28421205 )
2017
19
Systemic Amyloidosis and Cardiac Autonomic Neuropathy Associated with Waldenstrom's Macroglobulinemia. ( 28695027 )
2017
20
Editorial: Limited Utility of the Handgrip Test for the Diagnosis of Diabetic Cardiovascular Autonomic Neuropathy: "There's Time Enough, But None to Spare". ( 27781938 )
2017
21
Cardiac Autonomic Neuropathy Predicts All-Cause and Cardiovascular Mortality in Patients With End-Stage Renal Failure: AA 5-Year Prospective Study. ( 29142986 )
2017
22
Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia. ( 28928996 )
2017
23
Effect of ramipril/hydrochlorothiazide and ramipril/canrenone combination on atrial fibrillation recurrence in hypertensive type 2 diabetic patients with and without cardiac autonomic neuropathy. ( 28507568 )
2017
24
Managing supine hypertension in a patient with non-diabetic autonomic neuropathy receiving droxidopa for neurogenic orthostatic hypotension. ( 28623420 )
2017
25
Cardiovascular Autonomic Neuropathy Is an Independent Risk Factor for Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes. ( 28638827 )
2017
26
A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV). ( 27676246 )
2017
27
Permutation entropy analysis of heart rate variability for the assessment of cardiovascular autonomic neuropathy in type 1 diabetes mellitus. ( 28527351 )
2017
28
Cardiac Autonomic Neuropathy: Why Should Cardiologists Care about That? ( 29214181 )
2017
29
Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series. ( 28841844 )
2017
30
Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives. ( 29062239 )
2017
31
Potential Association of Triglyceride Glucose Index with Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus Patients. ( 28581270 )
2017
32
Letter: Effects of High-Dose I+-Lipoic Acid on Heart Rate Variability of Type 2 Diabetes Mellitus Patients with Cardiac Autonomic Neuropathy in Korea (Diabetes Metab J 2017;41:275-83). ( 29086540 )
2017
33
Pathogenetic Mechanisms of Outbreak and Development of Cardiac Autonomic Neuropathy in Patients with Metabolic Syndrome. ( 29124537 )
2017
34
Cardiac autonomic neuropathy in type 2 diabetes mellitus using Bellavere's score system. ( 29114191 )
2017
35
Delayed autonomic neuropathy in a patient with diethylene glycol poisoning: a case report. ( 29123883 )
2017
36
Continuous glucose monitoring adds information beyond HbA1c in well-controlled diabetes patients with early cardiovascular autonomic neuropathy. ( 28728915 )
2017
37
Combination of Ewing test, heart rate variability, and heart rate turbulence analysis for early diagnosis of diabetic cardiac autonomic neuropathy. ( 29137013 )
2017
38
Glycated albumin and its variability as an indicator of cardiovascular autonomic neuropathy development in type 2 diabetic patients. ( 29017498 )
2017
39
Anesthetic Management of a Patient With De Novo Hereditary Sensory and Autonomic Neuropathy, Type VII: A Case Report. ( 29077663 )
2017
40
Prediction of autonomic neuropathy in chronic kidney disease (stage 5) Iraqi patients (case control study). ( 28757390 )
2017
41
Cardiovascular Autonomic Neuropathy and Cardiovascular Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. ( 27803120 )
2017
42
Prevalence of Autonomic Neuropathy in Patients of Rheumatoid Arthritis and Its Correlation with Disease Severity. ( 28571182 )
2017
43
Cardiac Autonomic Neuropathy in Patients with Type 2 Diabetes Mellitus at High Risk for Foot Ulcers. ( 28459026 )
2017
44
Cardiovascular autonomic neuropathy. ( 27034552 )
2016
45
Alternative Quantitative Tools in the Assessment of Diabetic Peripheral and Autonomic Neuropathy. ( 27133153 )
2016
46
Validation of the Composite Autonomic Symptom Score 31 (COMPASS 31) for the assessment of symptoms of autonomic neuropathy in people with diabetes. ( 27990686 )
2016
47
[OP.1A.04] 24H AMBULATORY BLOOD PRESSURE MONITORING PROFILE IN PARKINSON'S DISEASE WITH AUTONOMIC NEUROPATHY. ( 27508622 )
2016
48
Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes. ( 27352953 )
2016
49
Autonomic Neuropathy and Endothelial Dysfunction in Patients With Impaired Glucose Tolerance or Type 2 Diabetes Mellitus. ( 27057914 )
2016
50
The influence of cardiovascular autonomic neuropathy on mortality in type 1 diabetic patients; 10-year follow-up. ( 26740046 )
2016

Variations for Autonomic Neuropathy

Expression for Autonomic Neuropathy

Search GEO for disease gene expression data for Autonomic Neuropathy.

Pathways for Autonomic Neuropathy

Pathways related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.79 NGF NPY NTRK1 SCN11A
2
Show member pathways
9.66 NGF NTRK1

GO Terms for Autonomic Neuropathy

Cellular components related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.92 CCK DST NTRK1 SCN11A

Biological processes related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.55 AKR1B1 ALB EPO NGF NTRK1
2 negative regulation of neuron apoptotic process GO:0043524 9.5 NGF NTRK1 RETREG1
3 response to axon injury GO:0048678 9.43 EPO NTRK1
4 response to electrical stimulus GO:0051602 9.4 EPO NTRK1
5 regulation of sensory perception of pain GO:0051930 9.37 CCK SCN11A
6 regulation of receptor activity GO:0010469 9.35 CCK EPO INS NGF NPY
7 neurotrophin TRK receptor signaling pathway GO:0048011 9.26 NGF NTRK1
8 positive regulation of Ras protein signal transduction GO:0046579 8.8 EPO NGF NTRK1

Molecular functions related to Autonomic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuropeptide hormone activity GO:0005184 9.16 CCK NPY
2 protein kinase activator activity GO:0030295 8.96 EPO WNK1
3 hormone activity GO:0005179 8.92 CCK EPO INS NPY

Sources for Autonomic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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