MCID: ATS005
MIFTS: 22

Autosomal Dominant Nonsyndromic Deafness malady

Categories: Genetic diseases, Ear diseases, Neuronal diseases, Rare diseases, Fetal diseases, Cardiovascular diseases

Aliases & Classifications for Autosomal Dominant Nonsyndromic Deafness

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Aliases & Descriptions for Autosomal Dominant Nonsyndromic Deafness:

Name: Autosomal Dominant Nonsyndromic Deafness 11 13
 
Autosomal Dominant Deafness 11

Classifications:



External Ids:

Disease Ontology11 DOID:0050564
ICD1028 H90.3

Summaries for Autosomal Dominant Nonsyndromic Deafness

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Disease Ontology:11 A nonsyndromic deafness characterized by an autosomal dominant inheritance mode.

MalaCards based summary: Autosomal Dominant Nonsyndromic Deafness, also known as autosomal dominant deafness, is related to autosomal dominant deafness-onychodystrophy syndrome and deafness, congenital, and onychodystrophy, autosomal dominant. An important gene associated with Autosomal Dominant Nonsyndromic Deafness is TECTA (Tectorin Alpha). Related mouse phenotype hearing/vestibular/ear.

Related Diseases for Autosomal Dominant Nonsyndromic Deafness

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Diseases in the Familial Deafness family:

Deafness, Autosomal Recessive 96 Deafness, Autosomal Recessive 36
Deafness, Autosomal Dominant 2b Deafness, Autosomal Recessive
Deafness, Autosomal Dominant 2a Deafness, Autosomal Recessive 32
Deafness, Autosomal Dominant 7 Deafness, Autosomal Dominant 49
Deafness, Autosomal Recessive 45 Deafness, Autosomal Recessive 9
Deafness, Autosomal Dominant 58 Deafness, Autosomal Recessive 70
Deafness, Autosomal Dominant 43 Deafness, Autosomal Recessive 88
Deafness, Autosomal Dominant 16 Deafness, Autosomal Recessive 27
Deafness, Autosomal Recessive 59 Deafness, Autosomal Recessive 6
Deafness, Autosomal Recessive 42 Deafness, Autosomal Dominant 18
Deafness, Autosomal Dominant 44 Deafness, Autosomal Dominant 6/14/38
Deafness, Autosomal Recessive 25 Deafness, Autosomal Dominant 27
Deafness, Autosomal Recessive 55 Deafness, Autosomal Recessive 26
Deafness, Autosomal Dominant 24 Deafness, Autosomal Recessive 49
Deafness, Autosomal Dominant 1 Deafness, Autosomal Dominant 54
Deafness, Autosomal Dominant 15 Deafness, Autosomal Dominant 52
Deafness, Autosomal Recessive 101 Deafness, Autosomal Recessive 91
Deafness, Autosomal Dominant 21 Deafness, Autosomal Recessive 104
Deafness, Autosomal Recessive 66 Deafness, Autosomal Dominant 13
Deafness, Autosomal Recessive 53 Deafness, Autosomal Dominant 31
Deafness, Autosomal Recessive 67 Deafness, Autosomal Recessive 103
Deafness, Autosomal Dominant 22 Deafness, Autosomal Recessive 37
Deafness, Autosomal Dominant 10 Deafness, Autosomal Recessive 38
Deafness, Autosomal Dominant 5 Deafness, Autosomal Recessive 44
Deafness, Autosomal Recessive 39 Deafness, Autosomal Recessive 61
Deafness, Autosomal Recessive 14 Deafness, Autosomal Recessive 17
Deafness, Autosomal Dominant 50 Deafness, Autosomal Recessive 13
Deafness, Autosomal Recessive 71 Deafness, Autosomal Dominant 28
Deafness, Autosomal Recessive 83 Deafness, Autosomal Dominant 47
Deafness, Autosomal Recessive 7 Deafness, Autosomal Dominant 36
Deafness, Autosomal Dominant 51 Deafness, Autosomal Recessive 31
Deafness, Autosomal Dominant 56 Deafness, Autosomal Recessive 79
Deafness, Autosomal Recessive 33 Deafness, Autosomal Recessive 30
Deafness, Autosomal Recessive 12 Deafness, Autosomal Recessive 23
Deafness, Autosomal Recessive 18a Deafness, Autosomal Recessive 18b
Deafness, Autosomal Dominant 59 Deafness, Autosomal Recessive 51
Deafness, Autosomal Recessive 93 Deafness, Autosomal Recessive 63
Deafness, Autosomal Recessive 2 Deafness, Autosomal Dominant 11
Deafness, Autosomal Dominant 8/12 Deafness, Autosomal Recessive 21
Deafness, Autosomal Recessive 24 Deafness, Autosomal Recessive 20
Deafness, Autosomal Recessive 62 Deafness, Autosomal Recessive 102
Deafness, Autosomal Dominant 48 Deafness, Autosomal Recessive 74
Deafness, Autosomal Recessive 84a Deafness, Autosomal Recessive 84b
Deafness, Autosomal Dominant 25 Deafness, Autosomal Dominant 64
Deafness, Autosomal Dominant 41 Deafness, Autosomal Recessive 1a
Deafness, Autosomal Dominant 3a Deafness, Autosomal Dominant 3b
Deafness, Autosomal Recessive 1b Deafness, Autosomal Dominant 33
Deafness, Autosomal Dominant 53 Deafness, Autosomal Recessive 5
Deafness, Autosomal Dominant 9 Deafness, Autosomal Dominant 23
Deafness, Autosomal Recessive 35 Deafness, Autosomal Recessive 16
Deafness, Autosomal Recessive 48 Deafness, Autosomal Dominant 30
Deafness , Autosomal Recessive 86 Deafness, Autosomal Dominant 65
Deafness, Autosomal Dominant 40 Deafness, Autosomal Recessive 22
Deafness, Autosomal Recessive 89 Deafness, Autosomal Recessive 85
Deafness, Autosomal Recessive 3 Deafness, Autosomal Dominant 20/26
Deafness, Autosomal Recessive 46 Deafness, Autosomal Recessive 77
Deafness, Autosomal Recessive 15 Deafness, Autosomal Recessive 68
Deafness, Autosomal Recessive 76 Deafness, Autosomal Dominant 4b
Deafness, Autosomal Dominant 4a Deafness, Autosomal Dominant 67
Deafness, Autosomal Recessive 65 Deafness, Autosomal Recessive 29
Deafness, Autosomal Recessive 8/10 Deafness, Autosomal Recessive 98
Deafness, Autosomal Dominant 17 Deafness, Autosomal Recessive 40
Deafness, Autosomal Recessive 28 Nonsyndromic Deafness
autosomal dominant nonsyndromic deafness Autosomal Recessive Nonsyndromic Deafness
Otof-Related Deafness Deafness, Autosomal Dominant, 68
Deafness, Autosomal Recessive, 97

Diseases related to Autosomal Dominant Nonsyndromic Deafness via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1autosomal dominant deafness-onychodystrophy syndrome11.9
2deafness, congenital, and onychodystrophy, autosomal dominant11.0
3nonsyndromic deafness10.3
4endometritis10.0KCNQ4, TECTA
5hyperimmunoglobulin syndrome9.6COCH, KCNQ4, TECTA
6pyelitis9.5COCH, KCNQ4, TECTA
7autosomal recessive nonsyndromic deafness9.3COCH, KCNQ4, TECTA
8self-healing papular mucinosis7.4CEACAM16, COCH, KCNQ4, MCM2, MYH14, SLC17A8
9x-linked nonsyndromic deafness7.0CEACAM16, COCH, KCNQ4, MCM2, MRPL12, MYH14

Graphical network of diseases related to Autosomal Dominant Nonsyndromic Deafness:



Diseases related to autosomal dominant nonsyndromic deafness

Symptoms for Autosomal Dominant Nonsyndromic Deafness

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Drugs & Therapeutics for Autosomal Dominant Nonsyndromic Deafness

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Epidemiology of Non-syndromic Dominant DeafnessCompletedNCT01150305

Search NIH Clinical Center for Autosomal Dominant Nonsyndromic Deafness

Genetic Tests for Autosomal Dominant Nonsyndromic Deafness

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Anatomical Context for Autosomal Dominant Nonsyndromic Deafness

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Animal Models for Autosomal Dominant Nonsyndromic Deafness or affiliated genes

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MGI Mouse Phenotypes related to Autosomal Dominant Nonsyndromic Deafness:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053777.8CEACAM16, COCH, KCNQ4, SLC17A8, TECTA

Publications for Autosomal Dominant Nonsyndromic Deafness

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Articles related to Autosomal Dominant Nonsyndromic Deafness:

idTitleAuthorsYear
1
A novel frameshift variant of COCH supports the hypothesis that haploinsufficiency is not a cause of autosomal dominant nonsyndromic deafness 9. (26631968)
2016
2
Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family. (26196677)
2015
3
Mapping of the alpha-tectorin gene (TECTA) to mouse chromosome 9 and human chromosome 11: a candidate for human autosomal dominant nonsyndromic deafness. (9503015)
1998

Variations for Autosomal Dominant Nonsyndromic Deafness

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Expression for genes affiliated with Autosomal Dominant Nonsyndromic Deafness

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Search GEO for disease gene expression data for Autosomal Dominant Nonsyndromic Deafness.

Pathways for genes affiliated with Autosomal Dominant Nonsyndromic Deafness

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GO Terms for genes affiliated with Autosomal Dominant Nonsyndromic Deafness

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Biological processes related to Autosomal Dominant Nonsyndromic Deafness according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of cell shapeGO:00083609.3COCH, MYH14
2sensory perception of soundGO:00076057.3CEACAM16, COCH, KCNQ4, MYH14, SLC17A8, TECTA

Sources for Autosomal Dominant Nonsyndromic Deafness

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet