Aliases & Classifications for Azoospermia

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Aliases & Descriptions for Azoospermia:

Name: Azoospermia 11 27 50 39 13 68
 
Spermatogenic Failure 11

Classifications:



External Ids:

Disease Ontology11 DOID:14227
ICD1030 N46.0, N46.01
ICD9CM32 606.0
MeSH39 D053713
NCIt45 C80076

Summaries for Azoospermia

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Wikipedia:71 Azoospermia is the medical condition of a man when sperm count is equal or less than 15 million/ml in... more...

MalaCards based summary: Azoospermia, also known as spermatogenic failure, is related to hypogonadism and y chromosome infertility, and has symptoms including infertility/subfertility male, infertility/subfertility male and incomplete spermatogenic arrest. An important gene associated with Azoospermia is DAZ1 (Deleted In Azoospermia 1). Affiliated tissues include testis, testes and liver, and related mouse phenotypes are endocrine/exocrine gland and reproductive system.

Disease Ontology:11 A male infertility disease characterized by the absence of any measurable level of sperm in semen.

Related Diseases for Azoospermia

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Diseases related to Azoospermia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1hypogonadism29.1AR, DAZ4, FSHB, USP9Y
2y chromosome infertility11.6
3spermatogenic failure 411.6
4spermatogenic failure, y-linked, 211.5
5young syndrome11.5
6spinocerebellar ataxia 3211.3
7spermatogenic failure 310.8
8spermatogenic failure 1210.7
9hypogonadotropic hypogonadism 24 without anosmia10.7
10spermatogenic failure 1410.7
11spermatogenic failure 1310.7
12spermatogenic failure, x-linked, 210.7
13androgen insensitivity, partial, with or without breast cancer10.7
14spermatogenesis arrest10.7
15infertility10.5
16oligospermia10.3
17varicocele10.1
18male infertility10.1
19retinitis pigmentosa, y-linked10.0DAZ1, DAZ2, DAZ3, DAZ4, USP9Y
20diabetes mellitus, insulin-resistant, with acanthosis nigricans10.0AR, AZF1, DAZ1, DAZ4
21cystic fibrosis10.0
22cryptorchidism10.0
23sertoli cell-only syndrome9.9
24inguinal hernia9.8
25intussusception9.8
26congenital bilateral absence of vas deferens9.7
27testicular germ cell tumor9.7
28spinal cord injury9.7
29hypospadias9.7
30spermatocele9.7
31klinefelter's syndrome9.7
32conjunctivitis9.7
33hypogonadotropism9.7
34hypoxia9.7
35pseudo pelger-huet anomaly9.5DAZ1, DAZ2, DAZ3, DAZ4, DDX3Y, RBMY1A1
36obesity9.5
37hyperprolactinemia9.5
38machado-joseph disease9.5
39fabry disease9.5
40pulmonic stenosis9.5
41radioulnar synostosis9.5
42hematopoietic stem cell transplantation9.5
43primary ciliary dyskinesia9.5
44lymphoma9.5
45omphalocele9.5
46hepatoid adenocarcinoma9.5
47cystinosis9.5
48arteriovenous malformation9.5
49synostosis9.5
50tuberculous epididymitis9.5

Graphical network of the top 20 diseases related to Azoospermia:



Diseases related to azoospermia

Symptoms & Phenotypes for Azoospermia

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UMLS symptoms related to Azoospermia:


infertility/subfertility male, incomplete spermatogenic arrest, complete spermatogenic arrest

MGI Mouse Phenotypes related to Azoospermia according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.8AR, BOLL, CFTR, DAZ2, FKBP6, FSHB
2MP:00053898.1AR, BOLL, CFTR, DAZ2, FKBP6, FSHB

Drugs & Therapeutics for Azoospermia

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Drugs for Azoospermia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 69)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MetforminapprovedPhase 41746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
2Ginsengapproved, nutraceuticalPhase 49250647-08-0
3
EnclomipheneinvestigationalPhase 416215690-57-0
Synonyms:
 
Clomiphene trans-form
4Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112778
5Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112767
6HormonesPhase 4, Phase 3, Phase 2, Phase 113979
7Hypoglycemic AgentsPhase 45733
8Insulin, Globin ZincPhase 44523
9EstrogensPhase 4, Phase 32470
10insulinPhase 44524
11Estrogen Receptor ModulatorsPhase 4630
12Selective Estrogen Receptor ModulatorsPhase 4586
13ZuclomiphenePhase 4162
14AnticoagulantsPhase 42516
15ClomiphenePhase 4162
16Calcium, DietaryPhase 45525
17Fertility AgentsPhase 4493
18Estrogen AntagonistsPhase 4, Phase 31315
19Chorionic GonadotropinPhase 4, Phase 2188
20Chelating AgentsPhase 41365
21CitrateNutraceuticalPhase 41106
22
Citric Acidnutraceutical, vet_approvedPhase 4110677-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
23
MethyltestosteroneapprovedPhase 2, Phase 3, Phase 154658-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
24
Testosteroneapproved, investigationalPhase 2, Phase 3, Phase 154658-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
25
Letrozoleapproved, investigationalPhase 3382112809-51-53902
Synonyms:
1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
112809-51-5
4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
AB00514009
AC-1193
AC1L1GYT
AKOS005145822
BIDD:GT0015
BIDD:PXR0130
BPBio1_001331
BRD-K88789588-001-03-2
BSPBio_001209
Bio-0057
C067431
C08163
C17H11N5
CAS-112809-51-5
CCRIS 8822
CGS 20267
CGS 20267, Femara, Piroxicam, Letrozole
CGS-20267
CHEBI:6413
CHEMBL1444
CID3902
CPD000466343
D00964
 
DB01006
FEM-345
Femara
Femara (TN)
Femera
HMS1571M11
HMS2051E08
HMS2089L22
HSDB 7461
I06-0022
LS-38788
Letoval
Letrozol
Letrozole
Letrozole (JAN/USP/INN)
Letrozole [USAN:INN]
MLS000759455
MLS001424038
MLS002584991
MolPort-003-848-373
NCGC00016973-01
NCGC00016973-02
NSC719345
Novartis Brand of Letrozole
Prestwick0_001025
Prestwick1_001025
Prestwick2_001025
Prestwick3_001025
S1235_Selleck
SAM001246649
SMR000466343
SPBio_003070
TL8000371
UNII-7LKK855W8I
ZINC03778874
letrozole
26Follicle Stimulating HormonePhase 3157
27LaxativesPhase 2, Phase 3520
28Testosterone undecanoatePhase 2, Phase 3, Phase 1546
29Testosterone 17 beta-cypionatePhase 2, Phase 3, Phase 1546
30
Testosterone enanthatePhase 2, Phase 3, Phase 1546315-37-79416
Synonyms:
17-((1-Oxoheptyl)oxy)androst-4-en-3-one
17-Hydroxyandrost-4-en-3-one, 17-heptanoate
17-Hydroxyandrost-4-en-3-one, 17-heptanoic acid
17beta-Enanthoxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-en-3-one enanthate
4-Androsten-17beta-ol-3-one 17-enanthate
4-Androsten-3-one 17beta-enanthate
Androgyn L.A.
Andropository
Androtardyl
Atlatest
DEA No. 4000
DePatestrye
Delatest
Delatestryl
Depo-Testro Med
Ditate
Durathate
Everone
 
Exten test
Malogen L.A.
Malogen L.A.200
Orquisteron-E
Primotestone
Reposo TMD
Testanthate
Testate
Testenate
Testinon
Testoenant
Testonenant
Testosterone 17-enanthate
Testosterone 17beta-heptanoate
Testosterone 17beta-heptanoic acid
Testosterone enantate
Testosterone heptoate
Testosterone heptoic acid
Testosterone heptylate
Testosterone oenanthate
Testostroval
31Gastrointestinal AgentsPhase 2, Phase 38109
32Anabolic AgentsPhase 2, Phase 3, Phase 1499
33Antineoplastic Agents, HormonalPhase 2, Phase 3, Phase 15407
34AndrogensPhase 2, Phase 3, Phase 11275
35Castor OilPhase 2, Phase 324
36CatharticsPhase 2, Phase 3520
37Aromatase InhibitorsPhase 3807
38Steroid Synthesis InhibitorsPhase 31718
39CastorNutraceuticalPhase 2, Phase 325
40
GoserelinapprovedPhase 222965807-02-547725, 5311128
Synonyms:
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
AC1NSK1T
CID5311128
Goserelin
Goserelin acetate
 
HMS2089D16
HS-2015
ICI-118630
MolPort-006-823-831
ZD-9393
Zoladex
goserelin
41Contraceptive AgentsPhase 2, Phase 11901
42Contraceptive Agents, MalePhase 2224
43
Coal tarapprovedPhase 11918007-45-2
Synonyms:
 
Coal tars
Tar, coal
44ST 1435Phase 111
45
Zincapproved22317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
46
Estradiolapproved, investigational, vet_approved128350-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol [USAN:INN]
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
 
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
47
Ironapproved11237439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
48
Vitamin Eapproved, nutraceutical, vet_approved40659-02-914985
Synonyms:
(+)-a-Tocopherol
(+)-alpha-Tocopherol
(+)-α-tocopherol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R,4'R,8'R)-a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
(2R,4'R,8'R)-α-tocopherol
(R,R,R)-a-Tocopherol
(R,R,R)-alpha-Tocopherol
(R,R,R)-α-tocopherol
5,7,8-Trimethyltocol
5,7,8-trimethyltocol
Amino-Opti-E
Aquasol E
D-alpha-Tocopherol
Daltose
Denamone
E-200 I.U. Softgels
 
E-Complex-600
E-Ferol
E-Vitamin succinate
Eprolin
Gordo-Vite E
Phytogermin
Phytogermine
RRR-alpha-tocopherol
RRR-alpha-tocopheryl
Tocopherol
Vitamin E
Vitamin Ea
Vitamin Plus E Softgells
Vitec
a-D-Tocopherol
a-Tocopherol
alpha-Tocopherol
alpha-delta-Tocopherol
alpha-tocopherol
d-α-tocopherol
delta-alpha-Tocopherol
49Antibodies6045
50Immunoglobulins6045

Interventional clinical trials:

(show all 43)
idNameStatusNCT IDPhase
1Clinical Research on Effectiveness and Safety of Treatment of Severe Oligospermia or Azoospermia With uFSHUnknown statusNCT02307994Phase 4
2Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical StudyCompletedNCT02204826Phase 4
3Metformin for the Treatment of Unexplained OligozspermiaRecruitingNCT01529177Phase 4
4FSH Treatment for Non-obstructive Azoospermic PatientsUnknown statusNCT02275169Phase 3
5The Comparison of Diagnostic TESE and TESA in Non-obstructive AzoospermicCompletedNCT01210326Phase 2, Phase 3
6Androgen for Leydig Cell ProliferationCompletedNCT01206270Phase 2, Phase 3
7Effect of Letrozole on Seminal Parameters in Men With Non Obstructive Azoospermia and Severe Oligozoospermia.RecruitingNCT02900105Phase 3
8Testicular Injection of Autologous Stem Cells for Treatment of Patients With AzoospermiaUnknown statusNCT02041910Phase 1, Phase 2
9Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched ControlsUnknown statusNCT00282477Phase 2
10GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive AzoospermiaRecruitingNCT02544191Phase 2
11MSCs For Treatment of Azoospermic PatientsRecruitingNCT02025270Phase 1, Phase 2
12Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility.Active, not recruitingNCT02641769Phase 1, Phase 2
13Contraception in Normal and Subnormal MenTerminatedNCT00167141Phase 2
14Study of the Safety, and Sperm and Gonadotropin Suppression of a Contraceptive Gel in Normal MenCompletedNCT00891228Phase 1
15Outcome of ICSI Using Cryopreserved Testicular Sperm From Infertile Men With Varicocele-associated AzoospermiaUnknown statusNCT02306499
16Spermatogonial Stem Cells in Azoospermic Patients: a Comparison Between Obstructive and Non-obstructive AzoospermiaUnknown statusNCT01178463
17Isolation of the Spermatic Cord in Mesh Inguinal Hernia RepairUnknown statusNCT01391455
18A Preliminary Study on Effect of Omega-3 on Human SpermUnknown statusNCT00479960Early Phase 1
19Estradiol and Testosterone Levels in Seminal Plasma of Men With Non-obstructive AzoospermiaCompletedNCT02255396
20Insulin Resistance in Idiopathic Oligospermia and AzoospermiaCompletedNCT01509482
21Microdissection Testicular Sperm Extraction (MicroTESE) and IVF-ICSI Outcome in Non-Obstructive Azoospermia (NOA)CompletedNCT00484081
22Study of Synapsis and Recombination in Male Meiosis and the Implications in InfertilityCompletedNCT02339272
23Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell InjectionCompletedNCT02414295
24Obtaining Undifferentiated Cells From Testis BiopsyCompletedNCT01375062
25Genetic Studies Spermatogenic FailureCompletedNCT00548977
26Chromosomal and Morphological Structure of Mature and Immature Male Germ Cells and Recognition of IL-18 in Testicular Tissue of Azoospermic MenCompletedNCT00544089
27Testicular Function After Iodine 131 Therapy in Papillary Carcinoma PatientsCompletedNCT01150318
28Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a VaricoceleCompletedNCT00044369
29Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of AzoospermiaRecruitingNCT02008799
30Secretory Azoospermia and FDG (Fluoro Deoxyglucose) PET-CTRecruitingNCT02043444
31Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and HypoandrogenismRecruitingNCT02137265
32HPV as a Possible Cause of AzoospermiaRecruitingNCT02329275
33Fertility Preservation in Cases of Klinefelter Syndrome.RecruitingNCT01918280
34Treatment of Severe Male Infertility - Predictive Factors (Imaging)RecruitingNCT02931721
35Modern Analyses of the Semen in Evaluating Male Fertility and Treatment Options of Male InfertilityRecruitingNCT02932865
36Reproductive Capacity and Iron Burden in ThalassemiaRecruitingNCT02308904
37Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive AzoospermiaEnrolling by invitationNCT02851966
38Quantitative MRI for Functional Imaging of the Testis: A New Methodology for Evaluation of the Infertile MaleEnrolling by invitationNCT02756325
39Testis Needle Aspiration of Sperm in Men With AzoospermiaNot yet recruitingNCT02418832
40Comparison of Medical Results of Testicular Sperm Extraction by Conventional Surgery and Microsurgical TrackNot yet recruitingNCT02773498
41The Effect of Low Electrical Current on Testicular Spermatocyte CountNot yet recruitingNCT02617173
42PET-MRI for Functional Imaging of the Testis: A Feasibility StudyNot yet recruitingNCT02669108
43Identification of Predictive Markers for Testis Cancer in a Population of Men With High RiskTerminatedNCT00820287

Search NIH Clinical Center for Azoospermia


Cochrane evidence based reviews: azoospermia

Genetic Tests for Azoospermia

About this section

Genetic tests related to Azoospermia:

id Genetic test Affiliating Genes
1 Azoospermia27

Anatomical Context for Azoospermia

About this section

MalaCards organs/tissues related to Azoospermia:

36
Testis, Testes, Liver, Bone marrow, Bone, Kidney, Spinal cord

Publications for Azoospermia

About this section

Articles related to Azoospermia:

(show top 50)    (show all 769)
idTitleAuthorsYear
1
Screening of Two Neighboring CFTR Mutations in Iranian Infertile Men with Non-Obstructive Azoospermia. (28042420)
2017
2
Reduced microRNA-188-3p expression contributes to apoptosis of spermatogenic cells in patients with azoospermia. (27868267)
2017
3
Untargeted metabolomic profiling of seminal plasma in non-obstructive azoospermia men: a non-invasive detection of spermatogenesis. (28058728)
2017
4
Leydig cell tumor of the testis with azoospermia and elevated delta4 androstenedione: case report. (27833751)
2016
5
Y chromosome haplogroups based genome-wide association study pinpoints revelation for interactions on non-obstructive azoospermia. (27628680)
2016
6
Re: Sperm Freezing to Address the Risk of Azoospermia on the Day of ICSI. (27479427)
2016
7
Microdissection testicular sperm extraction in Japanese patients with persistent azoospermia after chemotherapy. (27306218)
2016
8
Spermatogonial Stem Cells Protein Identification in In Vitro Culture from Non-Obstructive Azoospermia Patient. (27418868)
2016
9
Cytogenetic Investigation in a Group of Ten Infertile Men with Non-Obstructive Azoospermia: First Algerian 46, XX Syndrome. (27648416)
2016
10
Altered Crossover Distribution and Frequency in Spermatocytes of Infertile Men with Azoospermia. (27273078)
2016
11
Frequency of Y Chromosome Microdeletions Among Iranian Infertile Men with Azoospermia and Severe Oligozoospermia: A Meta-analysis. (27920999)
2016
12
A seminal molecular marker for sperm presence in non-obstructive azoospermia? (27492894)
2016
13
Azoospermia in rabbits following an intravas injection of Vasalgel a8c. (27030808)
2016
14
Testicular Spermatozoa Are of Better Quality Than Epididymal Spermatozoa in Patients With Obstructive Azoospermia. (27888149)
2016
15
Re: Comparison of Microdissection Testicular Sperm Extraction, Conventional Testicular Sperm Extraction, and Testicular Sperm Aspiration for Nonobstructive Azoospermia: A Systematic Review and Meta-Analysis. (27186769)
2016
16
Oestrogen receptors beta genotype in infertile Egyptian men with nonobstructive azoospermia. (27038350)
2016
17
Correlation of genetic results with testicular histology, hormones and sperm retrieval in nonobstructive azoospermia patients with testis biopsy. (27921326)
2016
18
Couples with non-obstructive azoospermia are interested in future treatments with artificial gametes. (27130613)
2016
19
Relationship between AZFc deletions and testicular histology in infertile South Chinese men with azoospermia and severe oligospermia. (27812445)
2016
20
Predictive factors for sperm recovery after varicocelectomy in men with non-obsturctive azoospermia. (27545577)
2016
21
Pregnancy resulting from IMSI after testicular biopsy in a patient with obstructive azoospermia. (27833987)
2016
22
Analysis of partial azoospermia factor c deletion and DAZ copy number in azoospermia and severe oligozoospermia. (27739146)
2016
23
A RARE COMBINATION OF 45,X/46,XY MOSAICISM AND Y CHROMOSOME MICRODELETION IN AN INFERTILE MAN WITH AZOOSPERMIA. (27192898)
2016
24
The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia. (26843391)
2016
25
Re: Salvage Micro-Dissection Testicular Sperm Extraction; Outcome in Men with Non-Obstructive Azoospermia with Previous Failed Sperm Retrievals. (27186770)
2016
26
Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong. (27687508)
2016
27
Azoospermia and the cancer patient: are there any options? (27048789)
2016
28
Simultaneous expression analysis of deleted in azoospermia-family genes and CDC25A: their potential as a predictor for successful testicular sperm extraction. (27568999)
2016
29
A novel stepwise micro-TESE approach in non obstructive azoospermia. (27176005)
2016
30
Predictors for successful sperm retrieval of salvage microdissection testicular sperm extraction (TESE) following failed TESE in nonobstructive azoospermia patients. (27444399)
2016
31
Testicular histology may predict the successful sperm retrieval in patients with non-obstructive azoospermia undergoing conventional TESE: a diagnostic accuracy study. (27655389)
2016
32
A differential cytokine expression profile before and after rFSH treatment in Sertoli cell cultures of men with nonobstructive azoospermia. (27444581)
2016
33
Expression level of chromodomain Y (CDY): potential marker for prediction of sperm recovery in non-obstructive azoospermia. (27525321)
2016
34
Azoospermia and testicular biopsy before intra-cytoplasmic sperm injection: Does the type of anesthesia make a difference? (27003978)
2016
35
ICSI outcomes in men undergoing TESE for azoospermia and impact of maternal age. (27198124)
2016
36
Re: Outcomes of Microdissection Testicular Sperm Extraction in Men with Nonobstructive Azoospermia Due to Maturation Arrest. (27186771)
2016
37
Effects of human chorionic gonadotropin on testicular interstitial tissues in men with non-obstructive azoospermia. (27860441)
2016
38
A Novel Missense Mutation in USP26 Gene Is Associated With Nonobstructive Azoospermia. (27089915)
2016
39
CHES-1-like, the ortholog of a non-obstructive azoospermia-associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis. (27281616)
2016
40
Association of polymorphisms of miRNA biogenesis related genes DICER and DROSHA with azoospermia]. (27264823)
2016
41
A novel variant of androgen receptor is associated with idiopathic azoospermia. (27498682)
2016
42
Prediction model for obtaining spermatozoa with testicular sperm extraction in men with non-obstructive azoospermia. (27406950)
2016
43
Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans. (27035939)
2016
44
BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells. (27632217)
2016
45
Comparison of intracytoplasmic sperm injection with testicular spermatozoa success in infertile men with obstructive and non-obstructive azoospermia; a retrospective analysis. (27931129)
2016
46
X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in han chinese population. (27107421)
2016
47
Discrimination and characterization of Sertoli cell-only syndrome in non-obstructive azoospermia using cell-free seminal DDX4. (27211570)
2016
48
A novel functional variant in Wilms' tumor 1 (WT1) is associated with idiopathic non-obstructive azoospermia. (27990711)
2016
49
Antisperm protein targets in azoospermia men. (27110078)
2016
50
Expression ratio of histone demethylase KDM3A to protamine-1 mRNA is predictive of successful testicular sperm extraction in men with obstructive and non-obstructive azoospermia. (27027467)
2016

Variations for Azoospermia

About this section

Copy number variations for Azoospermia from CNVD:

6 (show all 15)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
12187597116907252117095954Genomic rearrangementCFTRAzoospermia
2266752Y157772954MicrodeletionAzoospermia
3266760Y157772954MicrodeletionsAzoospermia
4266846Y1130000057772954MicrodeletioAzoospermia
5266849Y1130000057772954MicrodeletionAzoospermia
6266862Y1130000057772954MicrodeletionDAZAzoospermia
7266959Y174481503174538309DeletionAZFSpermatogenic Failure
8266963Y174481503174538309MicrodeletionAZFAzoospermia
9266968Y174481503174538309MicrodeletionAZFAAzoospermia
10266969Y174481503174538309MicrodeletionAZFAAzoospermia
11267104Y2353979725607639DeletionBPY2Azoospermia
12267118Y2368488923754627DeletionDAZAzoospermia
13267153Y2460076326180436DeletionCDY1Azoospermia
14267157Y2473896826042240DeletionCSPG4LYAzoospermia
15267158Y2476550126015710DeletionGOLGA2LYAzoospermia

Expression for genes affiliated with Azoospermia

About this section
Search GEO for disease gene expression data for Azoospermia.

Pathways for genes affiliated with Azoospermia

About this section

GO Terms for genes affiliated with Azoospermia

About this section

Cellular components related to Azoospermia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1synaptonemal complexGO:00007959.9FKBP6, TEX11
2cytoplasmGO:00057377.9AR, BOLL, CFTR, DAZ1, DAZ3, DAZ4

Biological processes related to Azoospermia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1meiotic nuclear divisionGO:000712610.7BOLL, FKBP6
2positive regulation of translational initiationGO:004594810.5BOLL, DAZ1, DAZL
3regulation of gene expressionGO:001046810.4AR, DDX3Y, SOHLH1
4multicellular organism developmentGO:000727510.2BOLL, DAZ1, DAZ3, DAZ4, DAZL
5cell differentiationGO:00301549.7BOLL, DAZ1, DAZ3, DAZ4, DAZAP1, FKBP6
6spermatogenesisGO:00072838.3AR, BOLL, DAZ1, DAZ3, DAZ4, DAZAP1

Molecular functions related to Azoospermia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleotide bindingGO:00001669.9BOLL, DAZ1, DAZ3, DAZ4, DAZAP1, DAZL
2translation activator activityGO:00084949.8BOLL, DAZ1, DAZL
3RNA bindingGO:00037239.3BOLL, DAZ1, DAZ3, DAZ4, DAZAP1, DAZL

Sources for Azoospermia

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet