MCID: BCK006
MIFTS: 38

Back Pain malady

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Summaries for Back Pain

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Sources:
34MedlinePlus, 44NINDS, 65Wikipedia, 33MalaCards
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MedlinePlus:34 If you've ever groaned, "oh, my aching back!", you are not alone. back pain is one of the most common medical problems, affecting 8 out of 10 people at some point during their lives. back pain can range from a dull, constant ache to a sudden, sharp pain. acute back pain comes on suddenly and usually lasts from a few days to a few weeks. back pain is called chronic if it lasts for more than three months. most back pain goes away on its own, though it may take awhile. taking over-the-counter pain relievers and resting can help. however, staying in bed for more than 1 or 2 days can make it worse. if your back pain is severe or doesn't improve after three days, you should call your health care provider. you should also get medical attention if you have back pain following an injury. treatment for back pain depends on what kind of pain you have, and what is causing it. it may include hot or cold packs, exercise, medicines, injections, complementary and alternative treatments, and sometimes surgery. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards: Back Pain is related to spinal stenosis and degenerative disc disease. An important gene associated with Back Pain is COL11A2 (collagen, type XI, alpha 2), and among its related pathways are Protein digestion and absorption and Collagen biosynthesis and modifying enzymes. The compounds oleic acid and ether have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes.

NINDS:44 Acute or short-term low back pain generally lasts from a few days to a few weeks. Most acute back pain is the result of trauma to the lower back or a disorder such as arthritis. Pain from trauma may be caused by a sports injury, work around the house or in the garden, or a sudden jolt such as a car accident or other stress on spinal bones and tissues. Symptoms may range from muscle ache to shooting or stabbing pain, limited flexibility and range of motion, or an inability to stand straight. Chronic back pain is pain that persists for more than 3 months. It is often progressive and the cause can be difficult to determine.

Wikipedia:65 Back pain is pain felt in the back that usually originates from the muscles, nerves, bones, joints or... more...

Aliases & Classifications for Back Pain

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44NINDS, 34MedlinePlus
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Aliases & Descriptions:

back pain 44 34


Related Diseases for Back Pain

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Back Pain:



Diseases related to back pain

Symptoms for Back Pain

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Drugs & Therapeutics for Back Pain

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Back Pain

Search NIH Clinical Center for Back Pain

Genetic Tests for Back Pain

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Anatomical Context for Back Pain

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Sources:
33MalaCards
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MalaCards organs/tissues related to Back Pain:

33
Bone, Skin, Testes, Brain, Spinal cord, Breast, Myeloid, Cortex, Prostate, Monocytes, Pituitary, Heart, Bone marrow, Eye, Lymph node, Temporal lobe

Animal Models for Back Pain or affiliated genes

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Publications for Back Pain

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52PubMed
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Articles related to Back Pain:

(show top 50)    (show all 739)
idTitleAuthorsYear
1
Dose or content? Effectiveness of pain rehabilitation programs for patients with chronic low back pain: A systematic review. (24135435)
2014
2
Avoidance of affective pain stimuli predicts chronicity in patients with acute low back pain. (24028848)
2014
3
Effectiveness of Mat Pilates or Equipment-Based Pilates Exercises in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial. (24435105)
2014
4
Osteopathic manual treatment and ultrasound therapy for chronic low back pain: an illustration of osteopathic semantic confusion. (24384968)
2014
5
Osteopathic manual treatment and ultrasound therapy for chronic low back pain: an illustration of osteopathic semantic confusion. (24005084)
2013
6
Low Back Pain in a Natural Disaster. (23763663)
2013
7
Diastematomyelia presenting in adulthood as back pain. (21904190)
2013
8
Determining the pain-affecting factors of university students with nonspecific low back pain. (24409020)
2013
9
Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study. (23522322)
2013
10
Intradiscal pulsed radiofrequency for chronic lumbar discogenic low back pain: a one year prospective outcome study using discoblock for diagnosis. (23877468)
2013
11
Health Care Utilisation and Out-of-Pocket Expenditure Associated with Back Pain: A Nationally Representative Survey of Australian Women. (24376716)
2013
12
Treatment persistence and changes in fracture risk, back pain, and quality of life amongst patients treated with teriparatide in routine clinical care in France: Results from the European Forsteo Observational Study. (23796729)
2013
13
Differences in Transversus Abdominis Muscle Function between Chronic Low Back Pain Patients and Healthy Subjects at Maximum Expiration: Measurement with Real-time Ultrasonography. (24259871)
2013
14
Answer to the Letter to the Editor of K. Shubhakaran et al. entitled "Backache and infection" concerning "Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized controlled trial of efficacy" by Albert H.B. et al., Eur Spine J (2013) 22:697-707. (24026169)
2013
15
The Role of Sacrolumbar Fat Grafting in the Treatment of Spinal Fusion Instrumentation-Related Chronic Low Back Pain: A Preliminary Report. (24299726)
2013
16
The Effects of Stabilization and Mckenzie Exercises on Transverse Abdominis and Multifidus Muscle Thickness, Pain, and Disability: A Randomized Controlled Trial in NonSpecific Chronic Low Back Pain. (24409016)
2013
17
Paravertebral compartment syndrome after training causing severe back pain in an amateur rugby player: report of a rare case and review of the literature. (24004522)
2013
18
Comparison of the Hamstring Muscle Activity and Flexion-Relaxation Ratio between Asymptomatic Persons and Computer Work-related Low Back Pain Sufferers. (24259796)
2013
19
PACE--the first placebo controlled trial of paracetamol for acute low back pain: statistical analysis plan. (23937999)
2013
20
The smallest worthwhile effect of nonsteroidal anti-inflammatory drugs and physiotherapy for chronic low back pain: a benefit-harm trade-off study. (24021611)
2013
21
Yoga for chronic low back pain: a meta-analysis of randomized controlled trials. (23894731)
2013
22
Prognosis of chronic low back pain in patients presenting to a private community-based group exercise program. (23793557)
2013
23
Altered Disc Compression in Children With Idiopathic Low Back Pain: An Upright MRI Backpack Study. (24253789)
2013
24
Relationships Between Psychological Factors, Pain and Disability in Complex Regional Pain Syndrome and Low Back Pain. (24135903)
2013
25
Back pain in patients with degenerative spine disease and intradural spinal tumor: what to treat? when to treat? (24378627)
2013
26
Interventions for preventing and treating pelvic and back pain in pregnancy. (23904227)
2013
27
Consultations with complementary and alternative medicine practitioners amongst wider care options for back pain: a study of a nationally representative sample of 1,310 Australian women aged 60-65A years. (23949636)
2013
28
Iatrogenic consequences of early magnetic resonance imaging in acute, work-related, disabling low back pain. (23883826)
2013
29
Red flags for back pain. (24336004)
2013
30
Lumbopelvic motion during seated hip flexion in subjects with low-back pain accompanying limited hip flexion. (23989748)
2013
31
A systematic review of diagnostic imaging use for low back pain in the United States. (24216398)
2013
32
Dichotomizing sensory nerve fibers innervating both the lumbar vertebral body and the area surrounding the iliac crest: a possible mechanism of referred lateral back pain from lumbar vertebral body. (23970105)
2013
33
Effects of workplace, family and cultural influences on low back pain: What opportunities exist to address social factors in general consultations? (24315145)
2013
34
Lumbar fusion compared with conservative treatment in patients with chronic low back pain: a meta-analysis. (23820296)
2013
35
Neuronal differences between chronic low back pain and depression regarding long-term habituation to pain. (24167119)
2013
36
Severe chest and back pain and bilateral massive adrenal swelling in polycythemia vera: an uncommon case after esophagectomy. (22643542)
2012
37
Back pain among long-term survivors of childhood leukemia. (23108003)
2012
38
Back pain and leg complaints that revealed non-small cell carcinoma: a case study. (22014908)
2011
39
Chiropractic management of mechanical low back pain secondary to multiple-level lumbar spondylolysis with spondylolisthesis in a United States Marine Corps veteran: a case report. (19703668)
2009
40
ACP Journal Club. Review: Evidence for the effectiveness of surgery for low back pain, radiculopathy, and spinal stenosis is limited. (19841448)
2009
41
Spinal epidural abscess caused by group B Streptococcus in a diabetic woman presenting with febrile low back pain. (15973012)
2005
42
Thoracic osteoporotic fracture without upper back pain. (15314538)
2004
43
Greater trochanter bursitis pain syndrome in females with chronic low back pain and sciatica. (15587030)
2004
44
Are risk factors for atherothrombotic disease associated with back pain sickness absence? The Whitehall II Study. (10396544)
1999
45
Childhood leukemia presenting with back pain and vertebral compression fractures. (10220099)
1999
46
Evaluation of specific stabilizing exercise in the treatment of chronic low back pain with radiologic diagnosis of spondylolysis or spondylolisthesis. (9431633)
1997
47
Idiopathic juvenile osteoporosis. An unusual cause of back pain in an adolescent. (8581446)
1995
48
The epidemiology of male adolescent low back pain in a north suburban population of Melbourne, Australia. (7989878)
1994
49
Intrathecal administration of oxytocin induces analgesia in low back pain involving the endogenous opiate peptide system. (8009342)
1994
50
Magnetic resonance imaging in ochronosis, a rare cause of back pain. (8136578)
1994

Variations for Back Pain

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Expression for genes affiliated with Back Pain

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Back Pain

Search GEO for disease gene expression data for Back Pain.

Pathways for genes affiliated with Back Pain

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Sources:
50PathCards, 30KEGG, 55Reactome, 53QIAGEN, 5Cell Signaling Technology
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Compounds for genes affiliated with Back Pain

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45Novoseek, 29IUPHAR, 24HMDB, 11DrugBank, 51PharmGKB, 61Tocris Bioscience
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Compounds related to Back Pain according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oleic acid45 29 24 1112.5FABP4, FAAH
2ether45 5110.0CALCA, FAAH
3anandamide61 45 29 2411.8CALCA, FAAH

GO Terms for genes affiliated with Back Pain

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16Gene Ontology
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Cellular components related to Back Pain according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum lumenGO:0057889.4COL9A3, COL11A2
2proteinaceous extracellular matrixGO:0055789.3ASPN, CILP
3extracellular matrixGO:0310129.2ASPN, CILP

Biological processes related to Back Pain according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix disassemblyGO:0226179.7COL9A3, COL11A2
2collagen catabolic processGO:0305749.4COL9A3, COL11A2

Molecular functions related to Back Pain according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix structural constituent conferring tensile strengthGO:0300209.7COL9A3, COL11A2

Products for genes affiliated with Back Pain

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Back Pain

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet