MCID: BCT002
MIFTS: 52

Bacterial Vaginosis malady

Categories: Reproductive diseases

Aliases & Classifications for Bacterial Vaginosis

Aliases & Descriptions for Bacterial Vaginosis:

Name: Bacterial Vaginosis 12 52 3 14 69
Vaginosis, Bacterial 42

Classifications:



External Ids:

Disease Ontology 12 DOID:3385
MeSH 42 D016585
NCIt 47 C116973
UMLS 69 C0085166

Summaries for Bacterial Vaginosis

Disease Ontology : 12 A vaginitis that is characterized by a grayish vaginal discharge usually of foul odor and the presence of Gardnerella vaginalis.

MalaCards based summary : Bacterial Vaginosis, also known as vaginosis, bacterial, is related to vaginitis and vaginal discharge. An important gene associated with Bacterial Vaginosis is PEPD (Peptidase D), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Acetaminophen and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and t cells, and related phenotypes are cardiovascular system and hematopoietic system

CDC : 3 Some women with BV don't know they have it because they have no symptoms. Having BV can increase your chance of getting an STD.

Wikipedia : 71 Bacterial vaginosis (BV) is a disease of the vagina caused by excessive growth of bacteria. Common... more...

Related Diseases for Bacterial Vaginosis

Diseases related to Bacterial Vaginosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 279)
id Related Disease Score Top Affiliating Genes
1 vaginitis 11.5
2 vaginal discharge 11.3
3 cervicitis 10.5
4 candidiasis 10.4
5 trichomoniasis 10.4
6 intussusception 10.3 IL1B TNF
7 vulvovaginitis 10.3
8 vulvovaginal candidiasis 10.2
9 stocco dos santos syndrome 10.2 IL1B TNF
10 toxic optic neuropathy 10.2 IL1A IL1B
11 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.2 IL1B TNF
12 spondylometaphyseal dysplasia east-african type 10.2 TLR4 TNF
13 pyridoxal 5'-phosphate-dependent epilepsy 10.2 IL10 TNF
14 amyotrophic lateral sclerosis type 14 10.2 CXCL8 IL1B TNF
15 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.2 IL6 TNF
16 tubular renal disease-cardiomyopathy syndrome 10.2 IL10 TNF
17 endometritis 10.2
18 low compliance bladder 10.2 TLR4 TNF
19 nasal cavity cancer 10.2 CXCL8 IL1B TNF
20 tau syndrome 10.2 IL1B PRF1 TNF
21 retinal vascular occlusion 10.2 CXCL8 IL1B TNF
22 lagophthalmos 10.2 IL10 TNF
23 dyslexia 5 10.1 IL6 TNF
24 chlamydia 10.1
25 aortic atherosclerosis 10.1 IL6 TNF
26 oculomotor nerve paralysis 10.1 CXCL8 IL1B IL6
27 common peroneal nerve lesion 10.1 CXCL8 IL1B IL6
28 degenerative disc disease 10.1 IL6 TNF
29 cerebellar disease 10.1 IL1A IL1B TNF
30 twin-to-twin transfusion syndrome 10.1 IL1B TNF
31 multiple vertebral anomalies unusual facies 10.1 IL10 TNF
32 gastric leiomyoma 10.1 IL1B IL6 TLR4
33 megaloblastic anemia 10.1 IL10 IL1B TLR4
34 hiv-1 10.1
35 mucositis 10.1
36 pelvic inflammatory disease 10.1
37 bipolar i disorder 10.1 IL1B IL6 TNF
38 human immunodeficiency virus infectious disease 10.1 IL1B IL6 TNF
39 coronary arterial fistulas 10.1 CXCL8 IL10 TLR4
40 tinea capitis 10.1 IL1B IL6 TNF
41 measles 10.1 IL1B IL6 TNF
42 dextrocardia 10.1 IL1B IL6 TNF
43 spinal multifocal clear cell meningioma 10.1 CXCL8 IL1B IL6
44 benign neonatal seizures 10.1 IL1B IL6 TNF
45 mineral metabolism disease 10.1 IL1B IL6 TNF
46 conidiobolomycosis 10.1 CXCL8 IL10 TNF
47 migraine with aura 10.1 IL1B IL6 TNF
48 thymic neuroendocrine carcinoma 10.1 CXCL8 IL6 TNF
49 unilateral multicystic dysplastic kidney 10.1 IL6 TNF
50 plantar wart 10.1 CXCL8 IL10 TNF

Graphical network of the top 20 diseases related to Bacterial Vaginosis:



Diseases related to Bacterial Vaginosis

Symptoms & Phenotypes for Bacterial Vaginosis

MGI Mouse Phenotypes related to Bacterial Vaginosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 PEPD IL1A PRF1 IL1B TLR2 IL6
2 hematopoietic system MP:0005397 10.09 IL10 PEPD IL1A PRF1 IL1B TLR2
3 immune system MP:0005387 10.07 PEPD IL1A PRF1 IL1B TLR2 IL6
4 homeostasis/metabolism MP:0005376 10.06 IL10 PEPD IL1A PRF1 IL1B TLR2
5 integument MP:0010771 9.97 PEPD IL1A PRF1 IL1B TLR2 IL6
6 liver/biliary system MP:0005370 9.73 IL10 PRF1 TLR2 IL6 TLR4 TNF
7 muscle MP:0005369 9.63 IL10 PEPD TLR2 IL6 TLR4 TNF
8 neoplasm MP:0002006 9.56 IL1A PRF1 IL1B TLR2 IL6 IL10
9 nervous system MP:0003631 9.23 IL10 PEPD PRF1 IL1B TLR2 IL6

Drugs & Therapeutics for Bacterial Vaginosis

Drugs for Bacterial Vaginosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 171)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 4 103-90-2 1983
2
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
3
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 443-48-1 4173
4
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Early Phase 1 18323-44-9 29029
5
Desogestrel Approved Phase 4,Phase 2,Phase 3 54024-22-5 40973
6
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-28-2 5757 53477783
7
Ethinyl Estradiol Approved Phase 4,Phase 2,Phase 3 57-63-6 5991
8
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3 54048-10-1 40976 6917715
9
Tinidazole Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 19387-91-8 5479
10
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 22916-47-8 4189
11
Nystatin Approved, Vet_approved Phase 4,Phase 3 1400-61-9 11953884
12
Azithromycin Approved Phase 4,Phase 2,Phase 3 83905-01-5 55185 53477736 447043
13
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
14
Neomycin Approved, Vet_approved Phase 4,Phase 3 1404-04-2 8378
15
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
16
Clotrimazole Approved, Vet_approved Phase 4,Phase 3 23593-75-1 2812
17
Norelgestromin Approved Phase 4 53016-31-2 13752005
18
Ephedrine Approved Phase 4,Phase 2,Phase 3 299-42-3 9294
19
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3 90-82-4 7028
20
Norethindrone Approved Phase 4 68-22-4 6230
21 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Early Phase 1
22 Antibiotics, Antitubercular Phase 4,Phase 3
23 Antidotes Phase 4
24 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
25 Antioxidants Phase 4
26 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
27 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
28 Antiviral Agents Phase 4,Phase 3
29 Expectorants Phase 4
30 N-monoacetylcystine Phase 4
31 Protective Agents Phase 4,Phase 2
32 Respiratory System Agents Phase 4,Phase 2,Phase 3
33 Clindamycin palmitate Phase 4,Phase 3,Early Phase 1
34 Clindamycin phosphate Phase 4,Phase 3,Early Phase 1
35 Contraceptive Agents Phase 4,Phase 2,Phase 3
36 Contraceptives, Oral Phase 4,Phase 2,Phase 3
37 Estradiol 17 beta-cypionate Phase 4,Phase 2,Phase 3
38 Estradiol 3-benzoate Phase 4,Phase 2,Phase 3
39 Estradiol valerate Phase 4,Phase 2,Phase 3 979-32-8
40 Estrogens Phase 4,Phase 2,Phase 3
41 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
42 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
44 Polyestradiol phosphate Phase 4,Phase 2,Phase 3
45 Progestins Phase 4,Phase 2,Phase 3
46 Alkylating Agents Phase 4,Phase 3,Phase 2,Early Phase 1
47 Antifungal Agents Phase 4,Phase 3,Phase 2,Early Phase 1
48 Ionophores Phase 4,Phase 3
49 Antitubercular Agents Phase 4
50 Autonomic Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 164)
id Name Status NCT ID Phase
1 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4
2 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4
3 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4
4 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Unknown status NCT01779193 Phase 4
5 Treatment of Bacterial Vaginosis (BV) With Tinidazole Completed NCT00334633 Phase 4
6 Treatment of Bacterial Vaginosis Completed NCT00324818 Phase 4
7 Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study Completed NCT00464542 Phase 4
8 Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis Completed NCT00556179 Phase 4
9 Safety and Tolerability of Metronidazole Gel 1.3% Completed NCT02392026 Phase 4
10 Treatment of Bacterial Vaginosis Combined With Human Lactobacilli Completed NCT01245322 Phase 4
11 Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis Completed NCT00642980 Phase 4
12 N-Acetyl Cysteine for Prevention of Preterm Birth Completed NCT00568113 Phase 4
13 Clindamycin to Reduce Preterm Birth in a Low Resource Setting Completed NCT01800825 Phase 4
14 Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis Completed NCT02444481 Phase 4
15 DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women Completed NCT01874158 Phase 4
16 Antisepsis Regimen in the Surgical Treatment of Human Papilloma Virus Generated Cervical Lesions: Polyhexamethylene Biguanide Versus Chlorhexidine Completed NCT01740245 Phase 4
17 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4
18 PARIS or PAtch RIng Study: A Trial to Evaluate NuvaRing Versus OrthoEvra Completed NCT00269620 Phase 4
19 The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis Recruiting NCT03080740 Phase 4
20 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Recruiting NCT02042287 Phase 4
21 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Recruiting NCT02860845 Phase 4
22 Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity Recruiting NCT02445989 Phase 4
23 Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity Recruiting NCT02432404 Phase 4
24 Vaginal and Urinary Microbiome Trial Recruiting NCT02869165 Phase 4
25 Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis Not yet recruiting NCT03099408 Phase 4
26 The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis Not yet recruiting NCT02905890 Phase 4
27 Colposeptine for the Treatment of Bacterial Vaginosis Terminated NCT01153958 Phase 4
28 Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis Unknown status NCT02173184 Phase 3
29 A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis Unknown status NCT01089348 Phase 2, Phase 3
30 Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery Unknown status NCT00491270 Phase 3
31 The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients Unknown status NCT00536848 Phase 2, Phase 3
32 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis Unknown status NCT00889356 Phase 3
33 Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery Unknown status NCT01152528 Phase 3
34 Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections Unknown status NCT02186145 Phase 3
35 Maternal Genitourinary Infections and Adverse Perinatal Outcomes Unknown status NCT01572532 Phase 3
36 Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community Unknown status NCT00124878 Phase 3
37 Bacterial Vaginosis Home Screening to Prevent STDs Completed NCT00667368 Phase 3
38 Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosis Completed NCT01471457 Phase 2, Phase 3
39 Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis Completed NCT01125410 Phase 3
40 A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis Completed NCT01577537 Phase 3
41 A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis Completed NCT01577238 Phase 3
42 Treatment of Bacterial Vaginosis With Oral Tinidazole Completed NCT00229216 Phase 3
43 Lcr35® for Bacterial Vaginosis Prevention Completed NCT01160796 Phase 3
44 Safety and Efficacy Study to Treat Bacterial Vaginosis Completed NCT01621399 Phase 3
45 A Phase 3 Study of SYM-1219 Treatment of Women and Post-Menarchal Adolescent Girls With Bacterial Vaginosis Completed NCT02418845 Phase 3
46 A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) Completed NCT01293643 Phase 3
47 Open-Label Study to Evaluate the Safety of A Single Dose of SYM-1219, a Granule Formulation Containing 2 Grams of Secnidazole Completed NCT02452866 Phase 3
48 The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial Vaginosis Completed NCT01258556 Phase 2, Phase 3
49 BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Study Completed NCT00799214 Phase 2, Phase 3
50 A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment o Completed NCT02210689 Phase 3

Search NIH Clinical Center for Bacterial Vaginosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: vaginosis, bacterial

Genetic Tests for Bacterial Vaginosis

Anatomical Context for Bacterial Vaginosis

MalaCards organs/tissues related to Bacterial Vaginosis:

39
Testes, Colon, T Cells, Neutrophil, Cervix, Skin

Publications for Bacterial Vaginosis

Articles related to Bacterial Vaginosis:

(show top 50) (show all 682)
id Title Authors Year
1
A fruitful alliance: the synergy between Atopobium vaginae and Gardnerella vaginalis in bacterial vaginosis-associated biofilm. ( 26965870 )
2016
2
Correlates of Bacterial Vaginosis Over Long-Term Follow-Up: Impact of HIV Infection. ( 27841674 )
2016
3
Bacterial vaginosis: a critical analysis of current knowledge. ( 27396541 )
2016
4
Antimicrobial Resistance Genes and Modeling of Treatment Failure in Bacterial Vaginosis: Clinical Study of 289 Symptomatic Women. ( 26887782 )
2016
5
Molecular diagnosis of bacterial vaginosis: Does adjustment for total bacterial load or human cellular content improve diagnostic performance? ( 28042056 )
2016
6
The interplay of host immunity and environment on risk for bacterial vaginosis and associated reproductive health outcomes. ( 27056955 )
2016
7
The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations. ( 27874978 )
2016
8
Association between bacterial vaginosis and partner concurrency: a longitudinal study. ( 27645157 )
2016
9
Comparison of the Effects of Myrtus Communis L, Berberis Vulgaris and Metronidazole Vaginal Gel alone for the Treatment of Bacterial Vaginosis. ( 27134945 )
2016
10
Appreciable uncertainty regarding benefits and risks in the treatment of bacterial vaginosis to prevent preterm birth. ( 27935630 )
2016
11
Brief report: Associations between antecedent bacterial vaginosis and incident chlamydia and gonorrhea diagnoses, U.S. Army females, 2006-2012. ( 26930150 )
2016
12
Women's Views and Experiences of the Triggers for Onset of Bacterial Vaginosis and Exacerbating Factors Associated with Recurrence. ( 26930414 )
2016
13
Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities. ( 26810061 )
2016
14
Segmentation, Splitting, and Classification of Overlapping Bacteria in Microscope Images for Automatic Bacterial Vaginosis Diagnosis. ( 27479982 )
2016
15
Predictive value of the composition of the vaginal microbiota in bacterial vaginosis, a dynamic study to identify recurrence-related flora. ( 27253522 )
2016
16
Draft Genome Sequence of Criibacterium bergeronii gen. nov., sp. nov., Strain CCRI-22567T, Isolated from a Vaginal Sample from a Woman with Bacterial Vaginosis. ( 27587833 )
2016
17
Diversity of Vaginal Lactic Acid Bacterial Microbiota in 15 Algerian Pregnant Women with and without Bacterial Vaginosis by using Culture Independent Method. ( 27790434 )
2016
18
Distribution of human papillomaviruses and bacterial vaginosis in HIV positive women with abnormal cytology in Mombasa, Kenya. ( 27053945 )
2016
19
Complete Genome Sequence of Lactobacillus rhamnosus Strain BPL5 (CECT 8800), a Probiotic for Treatment of Bacterial Vaginosis. ( 27103719 )
2016
20
Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity. ( 27107961 )
2016
21
Progresses in vaginal microflora physiology and implications for bacterial vaginosis and candidiasis. ( 27215488 )
2016
22
Comparison between the efficacy of metronidazole vaginal gel and Berberis vulgaris (Berberis vulgaris) combined with metronidazole gel alone in the treatment of bacterial vaginosis. ( 27757195 )
2016
23
New Systems for Studying Intercellular Interactions in Bacterial Vaginosis. ( 27449872 )
2016
24
Bacterial vaginosis in association with spontaneous abortion and recurrent pregnancy losses. ( 27756985 )
2016
25
Bacterial vaginosis and adverse outcomes among full-term infants: a cohort study. ( 27658456 )
2016
26
Pathogenesis of Bacterial Vaginosis: Discussion of Current Hypotheses. ( 27449868 )
2016
27
Evaluation and subsequent optimizations of the quantitative AmpliSens Florocenosis/Bacterial vaginosis-FRT multiplex real-time PCR assay for diagnosis of bacterial vaginosis. ( 27714844 )
2016
28
A Positive Culture Result for Gardnerella Is Not Diagnostic of Bacterial Vaginosis. ( 27428605 )
2016
29
Bacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosis. ( 27090518 )
2016
30
Identification of vaginal bacteria diversity and it's association with clinically diagnosed bacterial vaginosis by denaturing gradient gel electrophoresis and correspondence analysis. ( 27503595 )
2016
31
Randomized, double-blind, comparative study of oral metronidazole and tinidazole in treatment of bacterial vaginosis. ( 28066102 )
2016
32
Pregnant women's attitudes about topical microbicides for the prevention and treatment of bacterial vaginosis during pregnancy. ( 27815549 )
2016
33
Genome Sequences of 15 Gardnerella vaginalis Strains Isolated from the Vaginas of Women with and without Bacterial Vaginosis. ( 27688326 )
2016
34
Correction for Hilbert et al., Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis. ( 27343296 )
2016
35
Serum vitamin D status and bacterial vaginosis prevalence and incidence in Zimbabwean women. ( 26945606 )
2016
36
Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The "Invisible Man" of Bacterial Vaginosis? ( 26989700 )
2016
37
Bacterial vaginosis: a synthesis of the literature on etiology, prevalence, risk factors, and relationship with chlamydia and gonorrhea infections. ( 26877884 )
2016
38
Prevalence of asymptomatic infections in sexually transmitted diseases attendees diagnosed with bacterial vaginosis, vaginal candidiasis, and trichomoniasis. ( 27890946 )
2016
39
Can one size fit all? Approach to bacterial vaginosis in sub-Saharan Africa. ( 26968525 )
2016
40
Bacterial Vaginosis and Pregnancy Outcome in Lagos, Nigeria. ( 26989754 )
2016
41
Current Treatment of Bacterial Vaginosis-Limitations and Need for Innovation. ( 27449869 )
2016
42
Bacterial Vaginosis Screening and Treatment in Pregnant Women. ( 27383417 )
2016
43
Cannonballs in Pap Smears: Double Whammy of Bacterial Vaginosis and Associated Infections. ( 26981615 )
2016
44
Does Bacterial Vaginosis Result From Fecal Transplantation? ( 27703036 )
2016
45
Women's Management of Recurrent Bacterial Vaginosis and Experiences of Clinical Care: A Qualitative Study. ( 27010725 )
2016
46
Treatment of bacterial vaginosis in pregnancy in order to reduce the risk of spontaneous preterm delivery - a clinical recommendation. ( 27258798 )
2016
47
Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study. ( 27078021 )
2016
48
Impact of periodic presumptive treatment for bacterial vaginosis on the vaginal microbiome among women participating in the Preventing Vaginal Infections trial. ( 28007924 )
2016
49
Utilization of molecular methods to identify prognostic markers for recurrent bacterial vaginosis. ( 27431434 )
2016
50
Impact of targeted counseling on reported vaginal hygiene practices and bacterial vaginosis: the HIV Prevention Trials Network 035 study. ( 27277555 )
2016

Variations for Bacterial Vaginosis

Expression for Bacterial Vaginosis

Search GEO for disease gene expression data for Bacterial Vaginosis.

Pathways for Bacterial Vaginosis

Pathways related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

(show top 50) (show all 68)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.97 CXCL8 DEFB4A IL10 IL1A IL1B IL6
2
Show member pathways
13.6 CXCL8 IL10 IL1A IL1B IL6 TLR4
3
Show member pathways
13.42 CXCL8 IL10 IL1A IL1B IL6 TLR2
4
Show member pathways
13.31 CXCL8 IL10 IL1A IL1B IL6 TNF
5
Show member pathways
13.26 CXCL8 IL10 IL1A IL1B IL6 TNF
6
Show member pathways
13.04 CXCL8 IL1A IL1B IL6 TLR2 TLR4
7
Show member pathways
12.96 CXCL8 IL10 IL1B IL6 TLR2 TLR4
8
Show member pathways
12.92 CXCL8 IL10 IL1A IL1B IL6 PRF1
9
Show member pathways
12.86 CXCL8 IL1A IL1B IL6 TLR2 TLR4
10
Show member pathways
12.76 IL1A IL1B IL6 TLR2 TLR4 TNF
11
Show member pathways
12.68 CXCL8 IL1B IL6 TNF
12
Show member pathways
12.65 IL10 IL1A IL1B IL6 TLR2 TLR4
13
Show member pathways
12.63 IL1A IL1B TLR2 TLR4 TNF
14
Show member pathways
12.56 IL10 IL1B IL6 TNF
15 12.51 IL10 IL1B TLR2 TNF
16
Show member pathways
12.49 IL10 IL1A IL1B IL6 TNF
17
Show member pathways
12.43 CXCL8 DEFB4A IL1B IL6 TLR2 TNF
18
Show member pathways
12.36 CXCL8 IL1A IL6 TLR2 TLR4 TNF
19
Show member pathways
12.35 IL10 IL1A IL1B TLR2 TLR4 TNF
20
Show member pathways
12.35 CXCL8 IL1A IL1B IL6 TLR4 TNF
21 12.25 IL10 IL1A IL1B IL6 TLR2 TLR4
22 12.24 CXCL8 IL10 IL1A IL1B IL6 TNF
23 12.22 IL6 TLR2 TLR4 TNF
24
Show member pathways
12.22 CXCL8 IL10 IL1A IL1B IL6 TNF
25
Show member pathways
12.19 CXCL8 DEFB4A IL1B IL6 TLR2 TLR4
26
Show member pathways
12.08 IL1A IL1B TLR2 TLR4
27 12.08 CXCL8 IL1A IL1B IL6 TLR4 TNF
28 12.05 IL1A IL1B TNF
29 12.04 CXCL8 IL10 IL1A IL1B IL6 TNF
30 12.02 IL1A IL1B TNF
31 12.02 CXCL8 IL1A IL1B IL6 TNF
32 12.01 CXCL8 IL1A IL1B IL6
33
Show member pathways
12 IL10 IL1B IL6 TLR2 TLR4 TNF
34
Show member pathways
11.99 IL1B IL6 TLR2 TLR4
35 11.97 IL10 IL6 TNF
36 11.97 IL1A IL1B IL6 TNF
37 11.96 CXCL8 IL1B TLR4 TNF
38 11.94 IL1B IL6 TNF
39 11.94 CXCL8 IL1A IL1B IL6 TLR4
40
Show member pathways
11.86 CXCL8 IL6 TLR4
41 11.85 IL10 IL1B IL6 TNF
42 11.85 CXCL8 IL10 IL1B IL6 TLR2 TLR4
43 11.83 IL10 IL6 TLR2 TLR4 TNF
44 11.79 IL10 IL1B TNF
45 11.76 CXCL8 IL1B IL6 TNF
46
Show member pathways
11.76 CXCL8 IL1A IL1B IL6 TNF
47 11.65 CXCL8 IL1A IL1B IL6 TLR2 TLR4
48 11.63 IL1B TLR2 TLR4 TNF
49 11.62 IL1A TLR4 TNF
50 11.62 CXCL8 IL1B IL6 TLR2 TLR4 TNF

GO Terms for Bacterial Vaginosis

Cellular components related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CXCL8 DEFB4A IL10 IL1A IL1B IL6
2 extracellular space GO:0005615 9.17 CXCL8 DEFB4A IL10 IL1A IL1B IL6

Biological processes related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.99 CXCL8 IL10 IL1A IL1B IL6 TLR2
2 positive regulation of gene expression GO:0010628 9.97 IL1A IL1B IL6 TLR2 TLR4 TNF
3 defense response to bacterium GO:0042742 9.94 DEFB4A IL10 TLR4 TNF
4 response to lipopolysaccharide GO:0032496 9.93 IL10 IL1B IL6 TLR2 TLR4
5 cytokine-mediated signaling pathway GO:0019221 9.9 IL1A IL1B IL6
6 defense response GO:0006952 9.9 CXCL8 DEFB4A TNF
7 positive regulation of angiogenesis GO:0045766 9.88 CXCL8 IL1A IL1B
8 activation of MAPK activity GO:0000187 9.88 IL1B TLR4 TNF
9 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.88 IL10 IL1B IL6 TNF
10 defense response to Gram-positive bacterium GO:0050830 9.86 DEFB4A IL6 TLR2 TNF
11 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.85 IL1B IL6 TLR2 TLR4 TNF
12 response to glucocorticoid GO:0051384 9.84 IL10 IL6 TNF
13 response to insulin GO:0032868 9.83 IL10 IL6 TLR2
14 positive regulation of JNK cascade GO:0046330 9.83 IL1B TLR4 TNF
15 cellular response to lipopolysaccharide GO:0071222 9.83 CXCL8 IL10 IL6 TLR4 TNF
16 defense response to Gram-negative bacterium GO:0050829 9.81 DEFB4A IL6 TLR4
17 positive regulation of interferon-gamma production GO:0032729 9.8 IL1B TLR4 TNF
18 positive regulation of nitric oxide biosynthetic process GO:0045429 9.78 IL1B IL6 TLR4 TNF
19 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.77 IL1A IL1B TNF
20 positive regulation of cytokine secretion GO:0050715 9.77 IL10 IL1A TNF
21 negative regulation of interleukin-6 production GO:0032715 9.76 IL10 TLR4 TNF
22 inflammatory response GO:0006954 9.76 CXCL8 IL10 IL1A IL1B IL6 TLR2
23 positive regulation of interleukin-10 production GO:0032733 9.73 TLR2 TLR4
24 defense response to protozoan GO:0042832 9.72 IL10 IL6
25 embryonic digestive tract development GO:0048566 9.72 CXCL8 TNF
26 negative regulation of lipid catabolic process GO:0050995 9.72 IL1B TNF
27 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.72 IL10 TNF
28 response to molecule of bacterial origin GO:0002237 9.72 CXCL8 IL10 TLR2
29 negative regulation of growth of symbiont in host GO:0044130 9.71 IL10 TNF
30 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.71 IL1B TNF
31 cellular response to hepatocyte growth factor stimulus GO:0035729 9.71 IL10 IL6
32 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.71 TLR2 TLR4
33 lipopolysaccharide-mediated signaling pathway GO:0031663 9.71 IL1B TLR2 TLR4 TNF
34 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.7 IL1B TNF
35 I-kappaB phosphorylation GO:0007252 9.7 TLR2 TLR4
36 regulation of cytokine secretion GO:0050707 9.7 TLR2 TLR4
37 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.7 IL10 IL1B TNF
38 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.69 IL1A IL1B
39 positive regulation of chemokine biosynthetic process GO:0045080 9.69 IL1B TNF
40 negative regulation of lipid storage GO:0010888 9.69 IL6 TNF
41 cellular response to lipoteichoic acid GO:0071223 9.68 TLR2 TLR4
42 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.68 TLR4 TNF
43 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.68 IL1A IL1B
44 endothelial cell apoptotic process GO:0072577 9.68 IL10 TNF
45 positive regulation of MHC class II biosynthetic process GO:0045348 9.67 IL10 TLR4
46 ectopic germ cell programmed cell death GO:0035234 9.67 IL1A IL1B
47 positive regulation of interleukin-8 production GO:0032757 9.67 IL1B TLR2 TLR4 TNF
48 regulation of establishment of endothelial barrier GO:1903140 9.66 IL1B TNF
49 negative regulation of cytokine secretion involved in immune response GO:0002740 9.65 IL10 TNF
50 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.65 IL6 TNF

Molecular functions related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 9.16 IL1A IL1B
2 cytokine activity GO:0005125 9.1 CXCL8 IL10 IL1A IL1B IL6 TNF
3 lipopolysaccharide receptor activity GO:0001875 8.96 TLR2 TLR4

Sources for Bacterial Vaginosis

3 CDC
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10 dbSNP
11 DGIdb
16 ExPASy
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60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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