MCID: BCT002
MIFTS: 51

Bacterial Vaginosis

Categories: Reproductive diseases

Aliases & Classifications for Bacterial Vaginosis

MalaCards integrated aliases for Bacterial Vaginosis:

Name: Bacterial Vaginosis 12 52 3 14 69
Vaginosis, Bacterial 42

Classifications:



External Ids:

Disease Ontology 12 DOID:3385
MeSH 42 D016585
NCIt 47 C116973
UMLS 69 C0085166

Summaries for Bacterial Vaginosis

Disease Ontology : 12 A vaginitis that is characterized by a grayish vaginal discharge usually of foul odor and the presence of Gardnerella vaginalis.

MalaCards based summary : Bacterial Vaginosis, also known as vaginosis, bacterial, is related to chancroid and vaginitis. An important gene associated with Bacterial Vaginosis is PEPD (Peptidase D), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Acetylcysteine and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and bone, and related phenotypes are cardiovascular system and hematopoietic system

CDC : 3 Some women with BV don't know they have it because they have no symptoms. Having BV can increase your chance of getting an STD.

Wikipedia : 72 Bacterial vaginosis (BV) is a disease of the vagina caused by excessive growth of bacteria. Common... more...

Related Diseases for Bacterial Vaginosis

Diseases related to Bacterial Vaginosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 306)
id Related Disease Score Top Affiliating Genes
1 chancroid 30.3 CXCL8 IL1B
2 vaginitis 11.5
3 vaginal discharge 11.3
4 granulomatous rosacea 10.7 LAP3 TNF
5 sternal cleft 10.7 IL1B TNF
6 fallopian tube carcinoma 10.6 CXCL8 LAP3
7 lacrimal apparatus disease 10.6 CXCL8 IL1B
8 pulmonary hypertension 10.6 IL1B TNF
9 walker dyson syndrome 10.6 IL1B TNF
10 toxic optic neuropathy 10.6 IL1A IL1B
11 cataract 10.6 IL1B TNF
12 spondylocostal dysostosis 4 10.6 TLR4 TNF
13 low compliance bladder 10.6 TLR4 TNF
14 ethmoid sinus cancer 10.5 IL1B TLR4
15 mycobacterium malmoense 10.5 CXCL8 TLR2
16 cervicitis 10.5
17 mycobacterium xenopi 10.5 CXCL8 TLR2
18 smarca4-deficient sarcoma of thorax 10.5 IL6 TNF
19 small intestine lymphoma 10.5 IL1A TNF
20 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.4 IL1B TNF
21 gliosarcoma 10.4 IL1A IL1B
22 amyotrophic lateral sclerosis type 10 10.4 CXCL8 IL1B TNF
23 epulis 10.4 CXCL8 IL1B TNF
24 cardiocranial syndrome 10.4 CXCL8 PRF1
25 aortic arch interruption 10.4 IL6 TNF
26 cutaneous leishmaniasis 10.4 IL6 TNF
27 candidiasis 10.4
28 x-linked dominant intellectual disability-epilepsy syndrome 10.4 IL1B IL6
29 tibialis tendinitis 10.4 CXCL8 IL1B TNF
30 schwannoma of ureter 10.4 CXCL8 IL6
31 psychotic disorder 10.4 CXCL8 IL6
32 plantar fascial fibromatosis 10.4 CXCL8 IL1B TNF
33 retinal vascular occlusion 10.4 CXCL8 IL1B TNF
34 toxoplasmosis 10.4 IL6 TNF
35 pure autonomic failure 10.4 IL10 TNF
36 tabatznik syndrome 10.4 IL1B PRF1 TNF
37 dyslexia 5 10.4 IL6 TNF
38 trichomoniasis 10.4
39 acute ackee fruit intoxication 10.4 IL10 TNF
40 macular dystrophy, atypical vitelliform 10.3 PRF1 TNF
41 fanconi syndrome 10.3 TLR2 TLR4
42 hypertensive heart disease 10.3 TLR2 TLR4
43 anencephaly and spina bifida x-linked 10.3 IL6 TNF
44 hidradenitis suppurativa 10.3 CXCL8 IL10
45 multiple familial trichoepithelioma 10.3 IL10 TNF
46 nonspecific interstitial pneumonia 10.3 CXCL8 IL10
47 oculomotor nerve paralysis 10.3 CXCL8 IL1B IL6
48 lagophthalmos 10.3 IL10 TNF
49 common peroneal nerve lesion 10.3 CXCL8 IL1B IL6
50 lung sarcoma 10.3 IL1A IL1B TNF

Graphical network of the top 20 diseases related to Bacterial Vaginosis:



Diseases related to Bacterial Vaginosis

Symptoms & Phenotypes for Bacterial Vaginosis

MGI Mouse Phenotypes related to Bacterial Vaginosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 IL10 IL1A IL1B IL6 PEPD PRF1
2 hematopoietic system MP:0005397 10.09 IL10 IL1A IL1B IL6 PEPD PRF1
3 immune system MP:0005387 10.07 IL10 IL1A IL1B IL6 LAP3 PEPD
4 homeostasis/metabolism MP:0005376 10.06 IL10 IL1A IL1B IL6 PEPD PRF1
5 integument MP:0010771 9.97 IL10 IL1A IL1B IL6 PEPD PRF1
6 liver/biliary system MP:0005370 9.73 IL6 PRF1 TLR2 TLR4 TNF IL10
7 muscle MP:0005369 9.63 TNF IL10 IL6 PEPD TLR2 TLR4
8 neoplasm MP:0002006 9.56 IL10 IL1A IL1B IL6 PRF1 TLR2
9 nervous system MP:0003631 9.23 IL10 IL1B IL6 PEPD PRF1 TLR2

Drugs & Therapeutics for Bacterial Vaginosis

Drugs for Bacterial Vaginosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 161)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
2
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 443-48-1 4173
3
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 18323-44-9 29029
4
Desogestrel Approved Phase 4,Phase 2,Phase 3 54024-22-5 40973
5
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-28-2 5757
6
Ethinyl Estradiol Approved Phase 4,Phase 2,Phase 3 57-63-6 5991
7
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3 54048-10-1 40976 6917715
8
Tinidazole Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 19387-91-8 5479
9
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 22916-47-8 4189
10
Nystatin Approved, Vet_approved Phase 4,Phase 3 1400-61-9 11953884
11
Azithromycin Approved Phase 4,Phase 2,Phase 3 83905-01-5 55185 53477736 447043
12
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
13
Neomycin Approved, Vet_approved Phase 4,Phase 3 1404-04-2 8378
14
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
15
Clotrimazole Approved, Vet_approved Phase 4,Phase 3 23593-75-1 2812
16
Norelgestromin Approved Phase 4 53016-31-2 13752005
17
Ephedrine Approved Phase 4,Phase 2,Phase 3 299-42-3 9294
18
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3 90-82-4 7028
19
Norethindrone Approved Phase 4 68-22-4 6230
20 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Early Phase 1
21 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2
22 Antidotes Phase 4
23 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
24 Antioxidants Phase 4
25 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
26 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
27 Antiviral Agents Phase 4
28 Expectorants Phase 4
29 N-monoacetylcystine Phase 4
30 Protective Agents Phase 4,Phase 2
31 Respiratory System Agents Phase 4,Phase 2,Phase 3
32 Clindamycin palmitate Phase 4,Phase 3,Phase 2,Early Phase 1
33 Clindamycin phosphate Phase 4,Phase 3,Phase 2,Early Phase 1
34 Contraceptive Agents Phase 4,Phase 2,Phase 3
35 Contraceptives, Oral Phase 4,Phase 2,Phase 3
36 Estradiol 17 beta-cypionate Phase 4,Phase 2,Phase 3
37 Estradiol 3-benzoate Phase 4,Phase 2,Phase 3
38 Estradiol valerate Phase 4,Phase 2,Phase 3 979-32-8
39 Estrogens Phase 4,Phase 2,Phase 3
40 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
41 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
42 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
43 Polyestradiol phosphate Phase 4,Phase 2,Phase 3
44 Progestins Phase 4,Phase 2,Phase 3
45 Alkylating Agents Phase 4,Phase 3,Phase 2,Early Phase 1
46 Antifungal Agents Phase 4,Phase 3,Phase 2,Early Phase 1
47 Ionophores Phase 4,Phase 3
48 Antitubercular Agents Phase 4
49 Autonomic Agents Phase 4,Phase 3,Phase 2
50 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 160)

id Name Status NCT ID Phase Drugs
1 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
2 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4 Lactobacillus acidophilus;Placebo
3 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4 Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
4 Treatment of Bacterial Vaginosis (BV) With Tinidazole Completed NCT00334633 Phase 4 tinidazole, metronidazole
5 Treatment of Bacterial Vaginosis Completed NCT00324818 Phase 4 metronidazole and azithromycin
6 Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study Completed NCT00464542 Phase 4 Metronidazole
7 Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis Completed NCT00556179 Phase 4 Lactoserum (Dermacyd Femina®)
8 Treatment of Bacterial Vaginosis Combined With Human Lactobacilli Completed NCT01245322 Phase 4 lactobacilli
9 Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis Completed NCT00642980 Phase 4 Clindamycin;Placebo;Clindamycin
10 Safety and Tolerability of Metronidazole Gel 1.3% Completed NCT02392026 Phase 4 Metronidazole Gel
11 N-Acetyl Cysteine for Prevention of Preterm Birth Completed NCT00568113 Phase 4 acetylcysteine in arm 1
12 Clindamycin to Reduce Preterm Birth in a Low Resource Setting Completed NCT01800825 Phase 4 Clindamycin;Placebo
13 Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis Completed NCT02444481 Phase 4 Polygynax combinaison of polymyxin, Neomycin and Nystatin
14 DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women Completed NCT01874158 Phase 4
15 Antisepsis Regimen in the Surgical Treatment of Human Papilloma Virus Generated Cervical Lesions: Polyhexamethylene Biguanide Versus Chlorhexidine Completed NCT01740245 Phase 4
16 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4 ClinSupV3 -soft gelatin capsule;ClinSupV3ER- Extended release tablet
17 PARIS or PAtch RIng Study: A Trial to Evaluate NuvaRing Versus OrthoEvra Completed NCT00269620 Phase 4 ethinyl estradiol/etonogestrel vaginal ring;ethinyl estradiol/norelgestromin transdermal contraceptive
18 The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis Recruiting NCT03080740 Phase 4 Clindamycin palmitate hydrochloride dispersible tablet;Metronidazole Tablet
19 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Recruiting NCT02042287 Phase 4 Metronidazole
20 Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis Recruiting NCT03099408 Phase 4 Metronidazole Oral;"Metronidazole" and "Lactobacillus"
21 Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity Recruiting NCT02445989 Phase 4 NuvaRing
22 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Recruiting NCT02860845 Phase 4 Antibiotic (Clindamycin);Antifungal (Clotrimazole)
23 Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity Recruiting NCT02432404 Phase 4 NuvaRing
24 The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis Not yet recruiting NCT02905890 Phase 4 Norethisterone enantate
25 Colposeptine for the Treatment of Bacterial Vaginosis Terminated NCT01153958 Phase 4 Colposeptine;Metronidazole
26 Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis Unknown status NCT02173184 Phase 3
27 A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis Unknown status NCT01089348 Phase 2, Phase 3 Lactofiltrum + Metronidazole;Metronidazole
28 The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients Unknown status NCT00536848 Phase 2, Phase 3 Metronidazole
29 Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery Unknown status NCT01152528 Phase 3
30 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis Unknown status NCT00889356 Phase 3 Clindamycin 100mg and Ketoconazole 400mg;Tetracycline 100mg and Amphotericin B 50mg
31 Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery Unknown status NCT00491270 Phase 3
32 Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections Unknown status NCT02186145 Phase 3 Association of metronidazole; nystatin and dexamethasone;Flagyl
33 Maternal Genitourinary Infections and Adverse Perinatal Outcomes Unknown status NCT01572532 Phase 3
34 Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community Unknown status NCT00124878 Phase 3
35 Bacterial Vaginosis Home Screening to Prevent STDs Completed NCT00667368 Phase 3 Metronidazole
36 Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosis Completed NCT01471457 Phase 2, Phase 3 Trimo-San gel
37 Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis Completed NCT01125410 Phase 3 Dequalinium chloride;Clindamycin
38 A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis Completed NCT01577537 Phase 3 1% SPL7013 Gel;Placebo
39 A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis Completed NCT01577238 Phase 3 1% SPL7013 Gel;Placebo
40 Treatment of Bacterial Vaginosis With Oral Tinidazole Completed NCT00229216 Phase 3 Tinidazole
41 Safety and Efficacy Study to Treat Bacterial Vaginosis Completed NCT01621399 Phase 3 Product 55394;Placebo Vehicle (non-treatment)
42 Lcr35® for Bacterial Vaginosis Prevention Completed NCT01160796 Phase 3 placebo;Lcr35®
43 A Phase 3 Study of SYM-1219 Treatment of Women and Post-Menarchal Adolescent Girls With Bacterial Vaginosis Completed NCT02418845 Phase 3 SYM-1219;Placebo
44 Open-Label Study to Evaluate the Safety of A Single Dose of SYM-1219, a Granule Formulation Containing 2 Grams of Secnidazole Completed NCT02452866 Phase 3 SYM-1219
45 The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial Vaginosis Completed NCT01258556 Phase 2, Phase 3
46 BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Study Completed NCT00799214 Phase 2, Phase 3 Placebo;Boric acid;Metronidazole
47 A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) Completed NCT01293643 Phase 3 100 mg clindamycin /800 mg ketoconazole vaginal ovule;100 mg tetracycline hydrochloride /50 mg amphotericin B cream
48 A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment o Completed NCT02210689 Phase 3 clindamycin phosphate vaginal cream 2%
49 Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in Malawi Completed NCT00140764 Phase 3 Metronidazole gel versus placebo gel
50 Once Daily In-situ Forming Versus Twice-daily Conventional Metronidazole Vaginal Gels for Treatment of Bacterial Vaginosis Completed NCT02365389 Phase 2, Phase 3 MTZ vaginal gel;Conventional MTZ vaginal gel

Search NIH Clinical Center for Bacterial Vaginosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: vaginosis, bacterial

Genetic Tests for Bacterial Vaginosis

Anatomical Context for Bacterial Vaginosis

MalaCards organs/tissues related to Bacterial Vaginosis:

39
Testes, Colon, Bone, Breast, Neutrophil, T Cells, Cervix

Publications for Bacterial Vaginosis

Articles related to Bacterial Vaginosis:

(show top 50) (show all 702)
id Title Authors Year
1
Prevalence of bacterial vaginosis in Portuguese pregnant women and vaginal colonization by Gardnerella vaginalis. ( 28875084 )
2017
2
Treatment failure of bacterial vaginosis is not associated with higher loads of Atopobium vaginae and Gardnerella vaginalis. ( 28792372 )
2017
3
Correction: Jang, S.-E.; et al. Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 Attenuate Gardnerella vaginalis-Infected Bacterial Vaginosis in Mice. Nutrients 2017, 9, 531. ( 28686189 )
2017
4
No. 211-Screening and Management of Bacterial Vaginosis in Pregnancy. ( 28729110 )
2017
5
Bacterial vaginosis and the risk of early miscarriage in women undergoing intracytoplasmic sperm injection cycles: a prospective cohort study. ( 28738736 )
2017
6
Gemini Cationic Amphiphiles Control Biofilm Formation by Bacterial Vaginosis Pathogens. ( 28893789 )
2017
7
Secnidazole Treatment of Bacterial Vaginosis: A Randomized Controlled Trial. ( 28697102 )
2017
8
Screening for bacterial vaginosis before intrauterine device insertion at a family planning clinic in south-west Nigeria. ( 28762360 )
2017
9
The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment. ( 28807017 )
2017
10
Risk of bacterial vaginosis, Trichomonas vaginalis and Candida albicans infection among new users of combined hormonal contraception vs LNG-IUS. ( 28849960 )
2017
11
Prevalence of Bacterial Vaginosis and Associated Risk Factors among Women Complaining of Genital Tract Infection. ( 28831285 )
2017
12
Cervical carcinogenesis, bacterial vaginosis, HPV-mRNA test and relapse of CIN2+ after loop electrosurgical excision procedure (LEEP). ( 28617533 )
2017
13
Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis. ( 28663088 )
2017
14
Bacterial Vaginosis and Cervical Intraepithelial Neoplasia: Is there an Association or is Co-Existence Incidental? ( 28610416 )
2017
15
A phase-3, double-blind, placebo-controlled study of the effectiveness and safety of single oral doses of secnidazole 2 g for the treatment of women with bacterial vaginosis. ( 28867602 )
2017
16
Bacterial vaginosis, human papilloma virus and herpes viridae do not predict vaginal HIV RNA shedding in women living with HIV in Denmark. ( 28569142 )
2017
17
Association of asymptomatic bacterial vaginosis with persistence of female genital human papillomavirus infection. ( 28681204 )
2017
18
Prevalence and distribution of Gardnerella vaginalis subgroups in women with and without bacterial vaginosis. ( 28583109 )
2017
19
Treatment of biofilms in bacterial vaginosis by an amphoteric tenside pessary-clinical study and microbiota analysis. ( 28903767 )
2017
20
Multiplex Peptide Nucleic Acid Fluorescence In Situ Hybridization (PNA-FISH) for Diagnosis of Bacterial Vaginosis. ( 28600771 )
2017
21
Bacterial Vaginosis and Pregnancy Outcome in Lagos, Nigeria. ( 26989754 )
2016
22
Predictive value of the composition of the vaginal microbiota in bacterial vaginosis, a dynamic study to identify recurrence-related flora. ( 27253522 )
2016
23
Bacterial vaginosis in association with spontaneous abortion and recurrent pregnancy losses. ( 27756985 )
2016
24
Does Bacterial Vaginosis Result From Fecal Transplantation? ( 27703036 )
2016
25
Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity. ( 27107961 )
2016
26
Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The "Invisible Man" of Bacterial Vaginosis? ( 26989700 )
2016
27
Treatment of bacterial vaginosis in pregnancy in order to reduce the risk of spontaneous preterm delivery - a clinical recommendation. ( 27258798 )
2016
28
Distribution of human papillomaviruses and bacterial vaginosis in HIV positive women with abnormal cytology in Mombasa, Kenya. ( 27053945 )
2016
29
The interplay of host immunity and environment on risk for bacterial vaginosis and associated reproductive health outcomes. ( 27056955 )
2016
30
Impact of targeted counseling on reported vaginal hygiene practices and bacterial vaginosis: the HIV Prevention Trials Network 035 study. ( 27277555 )
2016
31
Cannonballs in Pap Smears: Double Whammy of Bacterial Vaginosis and Associated Infections. ( 26981615 )
2016
32
Questions concerning "Polymicrobial Gardnerella biofilm resists repeated intravaginal antiseptic treatment in a subset of women with bacterial vaginosis: a preliminary report". ( 27619684 )
2016
33
Antimicrobial susceptibility and vaginolysin in Gardnerella vaginalis from healthy and bacterial vaginosis diagnosed women. ( 27694723 )
2016
34
Antimicrobial Resistance Genes and Modeling of Treatment Failure in Bacterial Vaginosis: Clinical Study of 289 Symptomatic Women. ( 26887782 )
2016
35
Draft Genome Sequence of Criibacterium bergeronii gen. nov., sp. nov., Strain CCRI-22567T, Isolated from a Vaginal Sample from a Woman with Bacterial Vaginosis. ( 27587833 )
2016
36
Correction for Hilbert et al., Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis. ( 27343296 )
2016
37
Comparison of the Effects of Myrtus Communis L, Berberis Vulgaris and Metronidazole Vaginal Gel alone for the Treatment of Bacterial Vaginosis. ( 27134945 )
2016
38
Current Treatment of Bacterial Vaginosis-Limitations and Need for Innovation. ( 27449869 )
2016
39
Molecular diagnosis of bacterial vaginosis: Does adjustment for total bacterial load or human cellular content improve diagnostic performance? ( 28042056 )
2016
40
Bacterial vaginosis and adverse outcomes among full-term infants: a cohort study. ( 27658456 )
2016
41
Genome Sequences of 15 Gardnerella vaginalis Strains Isolated from the Vaginas of Women with and without Bacterial Vaginosis. ( 27688326 )
2016
42
Women's Management of Recurrent Bacterial Vaginosis and Experiences of Clinical Care: A Qualitative Study. ( 27010725 )
2016
43
Prevalence of asymptomatic infections in sexually transmitted diseases attendees diagnosed with bacterial vaginosis, vaginal candidiasis, and trichomoniasis. ( 27890946 )
2016
44
Complete Genome Sequence of Lactobacillus rhamnosus Strain BPL5 (CECT 8800), a Probiotic for Treatment of Bacterial Vaginosis. ( 27103719 )
2016
45
Pathogenesis of Bacterial Vaginosis: Discussion of Current Hypotheses. ( 27449868 )
2016
46
Bacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosis. ( 27090518 )
2016
47
Correlates of Bacterial Vaginosis Over Long-Term Follow-Up: Impact of HIV Infection. ( 27841674 )
2016
48
Bacterial vaginosis: a synthesis of the literature on etiology, prevalence, risk factors, and relationship with chlamydia and gonorrhea infections. ( 26877884 )
2016
49
Progresses in vaginal microflora physiology and implications for bacterial vaginosis and candidiasis. ( 27215488 )
2016
50
Pregnant women's attitudes about topical microbicides for the prevention and treatment of bacterial vaginosis during pregnancy. ( 27815549 )
2016

Variations for Bacterial Vaginosis

Expression for Bacterial Vaginosis

Search GEO for disease gene expression data for Bacterial Vaginosis.

Pathways for Bacterial Vaginosis

Pathways related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CXCL8 DEFB4A IL10 IL1A IL1B IL6
2
Show member pathways
13.6 CXCL8 IL10 IL1A IL1B IL6 TLR4
3
Show member pathways
13.41 CXCL8 IL10 IL1A IL1B IL6 TLR2
4
Show member pathways
13.31 CXCL8 IL10 IL1A IL1B IL6 TNF
5
Show member pathways
13.25 CXCL8 IL10 IL1A IL1B IL6 TNF
6
Show member pathways
13.03 CXCL8 IL1A IL1B IL6 TLR2 TLR4
7
Show member pathways
12.94 CXCL8 IL10 IL1B IL6 TLR2 TLR4
8
Show member pathways
12.92 CXCL8 IL10 IL1A IL1B IL6 PRF1
9
Show member pathways
12.86 CXCL8 IL1A IL1B IL6 TLR2 TLR4
10
Show member pathways
12.75 IL1A IL1B IL6 TLR2 TLR4 TNF
11
Show member pathways
12.68 CXCL8 IL1B IL6 TNF
12
Show member pathways
12.65 IL10 IL1A IL1B IL6 TLR2 TLR4
13
Show member pathways
12.63 IL1A IL1B TLR2 TLR4 TNF
14
Show member pathways
12.56 IL10 IL1B IL6 TNF
15 12.51 IL10 IL1B TLR2 TNF
16
Show member pathways
12.49 IL10 IL1A IL1B IL6 TNF
17
Show member pathways
12.42 CXCL8 DEFB4A IL1B IL6 TLR2 TNF
18
Show member pathways
12.35 IL10 IL1A IL1B TLR2 TLR4 TNF
19
Show member pathways
12.35 CXCL8 IL1A IL1B IL6 TLR4 TNF
20 12.25 IL10 IL1A IL1B IL6 TLR2 TLR4
21 12.24 CXCL8 IL10 IL1A IL1B IL6 TNF
22 12.22 IL6 TLR2 TLR4 TNF
23
Show member pathways
12.22 CXCL8 IL10 IL1A IL1B IL6 TNF
24
Show member pathways
12.19 CXCL8 DEFB4A IL1B IL6 TLR2 TLR4
25
Show member pathways
12.08 IL1A IL1B TLR2 TLR4
26 12.08 CXCL8 IL1A IL1B IL6 TLR4 TNF
27 12.05 IL1A IL1B TNF
28 12.04 CXCL8 IL10 IL1A IL1B IL6 TNF
29 12.02 IL1A IL1B TNF
30 12.02 CXCL8 IL1A IL1B IL6 TNF
31 12.01 CXCL8 IL1A IL1B IL6
32
Show member pathways
12 IL10 IL1B IL6 TLR2 TLR4 TNF
33
Show member pathways
11.98 IL1B IL6 TLR2 TLR4
34 11.97 IL10 IL6 TNF
35 11.97 IL1A IL1B IL6 TNF
36 11.96 CXCL8 IL1B TLR4 TNF
37 11.94 IL1B IL6 TNF
38 11.94 CXCL8 IL1A IL1B IL6 TLR4
39
Show member pathways
11.86 CXCL8 IL6 TLR4
40 11.85 CXCL8 IL10 IL1B IL6 TLR2 TLR4
41 11.84 IL10 IL1B IL6 TNF
42 11.83 IL10 IL6 TLR2 TLR4 TNF
43 11.79 IL10 IL1B TNF
44 11.76 CXCL8 IL1B IL6 TNF
45
Show member pathways
11.76 CXCL8 IL1A IL1B IL6 TNF
46 11.65 CXCL8 IL1A IL1B IL6 TLR2 TLR4
47 11.63 IL1B TLR2 TLR4 TNF
48 11.62 CXCL8 IL1B IL6 TLR2 TLR4 TNF
49 11.61 IL1A TLR4 TNF
50 11.6 IL1A IL1B IL6 TNF

GO Terms for Bacterial Vaginosis

Cellular components related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 CXCL8 DEFB4A IL10 IL1A IL1B IL6
2 extracellular region GO:0005576 9.23 CXCL8 DEFB4A IL10 IL1A IL1B IL6

Biological processes related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.97 IL1A IL1B IL6 TLR2 TLR4 TNF
2 defense response to bacterium GO:0042742 9.94 DEFB4A IL10 TLR4 TNF
3 response to lipopolysaccharide GO:0032496 9.91 IL10 IL1B IL6 TLR2 TLR4
4 cytokine-mediated signaling pathway GO:0019221 9.9 IL1A IL1B IL6
5 defense response GO:0006952 9.9 CXCL8 DEFB4A TNF
6 positive regulation of angiogenesis GO:0045766 9.89 CXCL8 IL1A IL1B
7 activation of MAPK activity GO:0000187 9.88 IL1B TLR4 TNF
8 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.87 IL10 IL1B IL6 TNF
9 defense response to Gram-positive bacterium GO:0050830 9.86 DEFB4A IL6 TLR2 TNF
10 defense response to Gram-negative bacterium GO:0050829 9.85 DEFB4A IL6 TLR4
11 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.85 IL1B IL6 TLR2 TLR4 TNF
12 positive regulation of JNK cascade GO:0046330 9.84 IL1B TLR4 TNF
13 response to insulin GO:0032868 9.83 IL10 IL6 TLR2
14 response to glucocorticoid GO:0051384 9.83 IL10 IL6 TNF
15 cellular response to lipopolysaccharide GO:0071222 9.83 CXCL8 IL10 IL6 TLR4 TNF
16 positive regulation of interferon-gamma production GO:0032729 9.79 IL1B TLR4 TNF
17 positive regulation of nitric oxide biosynthetic process GO:0045429 9.78 IL1B IL6 TLR4 TNF
18 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.77 IL1A IL1B TNF
19 positive regulation of cytokine secretion GO:0050715 9.77 IL10 IL1A TNF
20 negative regulation of interleukin-6 production GO:0032715 9.76 IL10 TLR4 TNF
21 inflammatory response GO:0006954 9.76 CXCL8 IL10 IL1A IL1B IL6 TLR2
22 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.73 IL10 TNF
23 defense response to protozoan GO:0042832 9.73 IL10 IL6
24 embryonic digestive tract development GO:0048566 9.72 CXCL8 TNF
25 negative regulation of lipid catabolic process GO:0050995 9.72 IL1B TNF
26 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.72 IL1B TNF
27 response to molecule of bacterial origin GO:0002237 9.72 CXCL8 IL10 TLR2
28 negative regulation of growth of symbiont in host GO:0044130 9.71 IL10 TNF
29 cellular response to hepatocyte growth factor stimulus GO:0035729 9.71 IL10 IL6
30 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.71 IL1B TNF
31 lipopolysaccharide-mediated signaling pathway GO:0031663 9.71 IL1B TLR2 TLR4 TNF
32 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.7 TLR2 TLR4
33 I-kappaB phosphorylation GO:0007252 9.7 TLR2 TLR4
34 regulation of cytokine secretion GO:0050707 9.7 TLR2 TLR4
35 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.7 IL10 IL1B TNF
36 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.69 IL1A IL1B
37 cellular response to lipoteichoic acid GO:0071223 9.69 TLR2 TLR4
38 positive regulation of chemokine biosynthetic process GO:0045080 9.69 IL1B TNF
39 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.68 IL1A IL1B
40 negative regulation of lipid storage GO:0010888 9.68 IL6 TNF
41 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.68 TLR4 TNF
42 endothelial cell apoptotic process GO:0072577 9.67 IL10 TNF
43 positive regulation of MHC class II biosynthetic process GO:0045348 9.67 IL10 TLR4
44 ectopic germ cell programmed cell death GO:0035234 9.67 IL1A IL1B
45 positive regulation of interleukin-8 production GO:0032757 9.67 IL1B TLR2 TLR4 TNF
46 regulation of establishment of endothelial barrier GO:1903140 9.66 IL1B TNF
47 negative regulation of cytokine secretion involved in immune response GO:0002740 9.65 IL10 TNF
48 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.64 IL6 TNF
49 fever generation GO:0001660 9.63 IL1A IL1B
50 positive regulation of fever generation GO:0031622 9.63 IL1B TNF

Molecular functions related to Bacterial Vaginosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 9.16 IL1A IL1B
2 cytokine activity GO:0005125 9.1 CXCL8 IL10 IL1A IL1B IL6 TNF
3 lipopolysaccharide receptor activity GO:0001875 8.96 TLR2 TLR4

Sources for Bacterial Vaginosis

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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30 HGMD
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65 SNOMED-CT via HPO
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70 UMLS via Orphanet
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