MCID: BCT004
MIFTS: 51

Bacteriuria malady

Summaries for Bacteriuria

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Wikipedia:64 In medicine, bacteriuria denotes the presence of bacteria in urine not due to contamination from urine... more...

MalaCards: Bacteriuria is related to pyuria and bacteremia. An important gene associated with Bacteriuria is UMOD (uromodulin), and among its related pathways are Th17 Differentiation and Cell adhesion ECM remodeling. The drugs methenamine and methenamine hippurate and the compounds gamma globulin and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and heart, and related mouse phenotypes are renal/urinary system and cellular.

Disease Ontology:8 A urinary system disease which consists of the presence of bacteria in urine.

Aliases & Classifications for Bacteriuria

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH
See all sources

Aliases & Descriptions:

bacteriuria 8 10 45 61


External Ids:

Disease Ontology8 DOID:1412
SNOMED-CT57 61373006
MeSH35 D001437

Related Diseases for Bacteriuria

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Bacteriuria:



Diseases related to bacteriuria

Clinical Features for Bacteriuria

Drugs & Therapeutics for Bacteriuria

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Bacteriuria

Drug clinical trials:

Search ClinicalTrials for Bacteriuria

Search NIH Clinical Center for Bacteriuria

Search CenterWatch for Bacteriuria

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Bacteriuria

Anatomical Context for Bacteriuria

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Bacteriuria:

33
Brain, Spinal cord, Heart, Colon, Kidney, Prostate, B cells

Animal Models for Bacteriuria or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Bacteriuria

Sources:
51PubMed
See all sources

Articles related to Bacteriuria:

(show top 50)    (show all 557)
idTitleAuthorsYear
1
Bacterial colonization of double J stents and bacteriuria frequency. (24296053)
2013
2
Asymptomatic bacteriuria in diabetes mellitus patients in Southwest Cameroon. (24250304)
2013
3
Lack of positive association between falls and bacteriuria plus pyuria in older nursing home residents. (23581923)
2013
4
Asymptomatic bacteriuria is an independent predictor of urinary tract infections in an ambulatory cirrhotic population: a prospective evaluation. (24325582)
2013
5
Asymptomatic bacteriuria among elderly and middle-aged rural community-dwellers in South-Western Nigeria. (23874111)
2013
6
Clinical significance of Staphylococcus aureus bacteriuria at a tertiary care hospital. (23808717)
2013
7
Bacteriuria among primary and secondary school pupils in Akure North Local Government Area of Ondo State, Nigeria. (23330403)
2012
8
Vinegar for decreasing catheter-associated bacteriuria in long-term catheterized patients: a randomized controlled trial. (21708892)
2012
9
Asymptomatic bacteriuria and symptomatic urinary tract infections (UTI) in patients with diabetes mellitus in Tikur Anbessa Specialized University Hospital, Addis Ababa, Ethiopia. (23409407)
2012
10
Effect of canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, on bacteriuria and urinary tract infection in subjects with type 2 diabetes enrolled in a 12-week, phase 2 study. (22548646)
2012
11
Asymptomatic bacteriuria in pregnant mothers: a valid and cost-effective screening test in Bangladesh. (22185534)
2012
12
Study of urinary tract infection and bacteriuria in neonatal sepsis. (22421936)
2012
13
Outpatient urological procedures in antibiotic-naive patients with bladder cancer with asymptomatic bacteriuria. (22883017)
2012
14
Tolerance of bacteriuria after urinary diversion is linked to antimicrobial peptide activity. (21094991)
2011
15
Experimental colonization of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. (20638202)
2011
16
Virulence potential of Escherichia coli strains causing asymptomatic bacteriuria during pregnancy. (21918033)
2011
17
Asymptomatic bacteriuria among an obstetric population in Ibadan. (21984454)
2011
18
Bacteriuria and urinary retention following gynaecological surgery: comparing short vs long term catheterization. (21876574)
2010
19
Detection of bacteriuria and bacteremia in newborn calves by a catalase-based urine test. (21039861)
2010
20
Predictors of asymptomatic bacteriuria among obstetric population in Ibadan. (20642087)
2010
21
Microbial aetiology and sensitivity of asymptomatic bacteriuria among ante-natal mothers in Mulago hospital, Uganda. (21416036)
2010
22
Interexpert agreement on diagnosis of bacteriuria and urinary tract infection in hospitalized older adults. (19369509)
2009
23
Does bacteriuria interfere with albuminuria measurements of patients with diabetes? (19015170)
2009
24
Asymptomatic bacteriuria among the institutionalized elderly. (16835983)
2006
25
Evaluation of rapid urine screening tests to detect asymptomatic bacteriuria in pregnancy. (16936347)
2006
26
The postoperative bacteriuria score: a new way to predict nosocomial infection after prostate surgery. (16874646)
2006
27
No association between elevated post-void residual volume and bacteriuria in residents of nursing homes. (16025875)
2005
28
The uriscreen test to detect significant asymptomatic bacteriuria during pregnancy. (15629672)
2005
29
Bacteriuria and socioeconomic associations among pregnant women in Malatya, Turkey. (15913680)
2005
30
Bladder, bowel and bugs--bacteriuria in patients with intestinal urinary diversion. (15309491)
2004
31
A research on asymptomatic bacteriuria in 14- to 17-year-old female students. (15604577)
2004
32
Significance of bacteriuria in neurogenic bladder. (15162878)
2004
33
Nosocomial significant bacteriuria: prevalence and pattern of bacterial pathogens among children hospitalised for non-infective urinary tract disorders. (12769313)
2003
34
Effect of Hochu-ekki-to on asymptomatic MRSA bacteriuria. (12673409)
2003
35
Asymptomatic bacteriuria during pregnancy. Rapid answers using the Cochrane Library. (11852613)
2002
36
Pathogenesis of bacteriuria and infection in the spinal cord injured patient. (12113873)
2002
37
Staphylococcus aureus bacteriuria and surgical site infections by methicillin-resistant Staphylococcus aureus. (11295417)
2001
38
Virulence factors of Escherichia coli isolated from urine of diabetic women with asymptomatic bacteriuria. (11109113)
2000
39
Asymptomatic bacteriuria--important or not? (11018172)
2000
40
Asymptomatic bacteriuria may be considered a complication in women with diabetes. Diabetes Mellitus Women Asymptomatic Bacteriuria Utrecht Study Group. (10840989)
2000
41
Direct antimicrobial susceptibility testing in bacteriuria. (10230700)
1999
42
Significance of polymicrobic bacteriuria in a teaching hospital in Trinidad. (10189749)
1998
43
Virulence factors of Escherichia coli isolates from patients with symptomatic and asymptomatic bacteriuria and neuropathic bladders due to spinal cord and brain injuries. (9431932)
1998
44
Asymptomatic bacteriuria in pregnancy: epidemiological, clinical and microbiological approach. (10214459)
1998
45
Postpartum surveillance of bacteriuria in term vaginal deliveries. (9549982)
1998
46
Asymptomatic bacteriuria in the elderly. (9378928)
1997
47
Urethral obstruction of 6 hours or less causes bacteriuria, bacteremia, and pyelonephritis in mice challenged with "nonuropathogenic" Escherichia coli. (8335372)
1993
48
Fever, bacteriuria, and pyuria in spinal cord injured patients with indwelling urethral catheters. (2818157)
1989
49
Significance of asymptomatic bacteriuria in neurogenic bladder disease. (6369712)
1984
50
Perinephric and renal cortical abscess due to colon bacillus without bacteriuria or pyuria. (12991005)
1952

Genetic Variations for Bacteriuria

Expression for genes affiliated with Bacteriuria

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Bacteriuria

Search GEO for disease gene expression data for Bacteriuria.

Pathways for genes affiliated with Bacteriuria

Sources:
53R&D Systems, 12EMD Millipore, 30KEGG, 4Cell Signaling Technology, 60Tocris Bioscience, 52QIAGEN, 38NCBI BioSystems Database, 54Reactome, 56SinoBiological
See all sources

Pathways related to Bacteriuria according to GeneCards/GeneDecks:

(show all 28)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.1TLR1, TLR5
2
Cell adhesion ECM remodeling
Hide members
10.0ADAM8
310.0TLR2, TLR4
410.0TLR2, TLR4
5
Mucin expression in CF via IL-6, IL-17 signaling pathways
9.8TIRAP, TLR2, TLR5
69.8TLR1, TLR2, TLR4
79.7TIRAP, TLR4, IL8
89.7TLR4, TLR5, IL8
99.6TIRAP, TLR4, TLR2, TLR1
109.6TLR4, TLR2, TLR5, TLR1
11
Hide members
9.6TLR1, TLR5, TLR2, TLR4
129.6TLR4, TLR2, TLR5, TLR1
139.6TLR1, TLR5, TLR2, TLR4
14
Hide members
9.6TLR4, TLR2, TLR5, TLR1
15
Hide members
9.5TLR4, TLR2, TLR5, CD40LG
169.5IL8, CD40LG, TLR4, TIRAP
179.4TLR4, TLR2, TLR5, IL8
189.4IL8, CXCR1, CXCR2
19
Hide members
9.4TIRAP, TLR4, TLR2, TLR5, TLR1
20
Hide members
9.4TIRAP, TLR4, TLR2, TLR5, TLR1
21
Hide members
9.3TLR4, TLR2, TLR5, TLR1, CD40LG
22
Hide members
9.3TLR4, TLR2, TLR5, TLR1, CD79A
239.1IL8, TLR1, TLR5, TLR2, TLR4, TIRAP
24
Immune response Bacterial infections in normal airways
9.1TIRAP, TLR4, TLR2, TLR5, TLR1, IL8
25
Hide members
9.1TIRAP, TLR4, TLR2, TLR5, TLR1, IL8
26
Hide members
9.1TIRAP, TLR4, TLR2, TLR5, TLR1, IL8
27
Hide members
9.1TIRAP, TLR4, TLR2, TLR5, TLR1, IL8
28
Hide members
8.8TIRAP, TLR4, TLR2, TLR5, TLR1, CD40LG

Compounds for genes affiliated with Bacteriuria

Sources:
45Novoseek, 60Tocris Bioscience, 24HMDB, 29IUPHAR, 11DrugBank, 50PharmGKB
See all sources

Compounds related to Bacteriuria according to GeneCards/GeneDecks:

(show top 50)    (show all 94)
idCompoundScoreTop Affiliating Genes
1gamma globulin4510.5CRP
2endotoxin4510.4CXCR2
3cycloheximide4510.4CAT, TLR2
4pam3csk46010.2TLR4, TLR2, TLR1
5poly(i:c)6010.2TLR4, TLR1, TLR2
6pam2csk46010.2TLR4, TLR2, TLR1
7resiquimod45 6011.2TLR4, TLR2, TLR1
8superoxide45 2411.2CXCR2, PRF1
9loxoribine45 2911.2TLR4, TLR2, TLR5
10glucuronoxylomannan4510.1CD40LG, TLR4, TLR2
11sulfolipid i4510.1CD79A, CD40LG
12muramyl dipeptide45 2911.0IL8, TLR2, TLR4
13pneumococcal4510.0TLR4, CD79A, CD40LG
14hbd24510.0TLR4, TLR2, IL8
15cxcl62910.0CXCR1, CXCR2
16[125i]cxcl8 (human)299.9CXCR2, CXCR1
17bucillamine459.9CAT, CRP, CD79A
18cxcl1299.9CXCR1, CXCR2
19imiquimod45 29 60 1112.9IL8, TLR1, TLR4, TLR2
20polymyxin b459.9TLR2, IL8
21cxcl8299.9CXCR2, CXCR1
22mannan459.9CD79A, TLR4, TLR2, CD40LG
23pmma459.9CRP, CD79A, CD40LG
24azithromycin45 1110.8CD79A, CRP, IL8
25poly(i-c)459.8TLR4, TLR2, TLR5, IL8
26enterotoxin459.8PRF1, TLR2, CD79A
27anti-fungal459.8CD40LG, CD79A, TLR4, TLR2
28ccl345 2910.8IL8, CXCR1, TLR2, TLR4
29grogamma459.8IL8, CXCR2, CXCR1
30grobeta459.7IL8, CXCR1, CXCR2
31flagellin45 2910.7IL8, TLR1, TLR4, TLR2, TLR5
32rantes459.7TLR4, TLR2, TLR5, CXCR1, CD40LG
33peptidoglycan45 2910.7TLR5, TLR2, IL8, TLR1, TLR4
34sulfasalazine45 29 50 1112.7CD79A, CRP, CD40LG, IL8
35neopterin459.6CD79A, CD40LG, CRP, IL8
36okt3459.6CD40LG, CD79A, CRP
37allergens459.5ADAM8, CD79A, CD40LG, TLR4
38leukotriene b445 60 2411.4TLR2, CXCR2, CXCR1, IL8
39polysaccharide459.4CD79A, CD40LG, UMOD, TLR2, TLR4
40sb 20358045 6010.3TLR2, TLR4, CAT, IL8, CRP
41actinomycin d459.2CD40LG, CXCR1, IL8, CAT, TLR4, TLR2
42lipoteichoic acid459.2TLR1, TLR4, TLR2, TLR5, IL8, CXCR2
43n acetylcysteine459.1CAT, CRP, CD40LG, TLR4, CD79A, IL8
44groalpha459.1CXCR2, IL8, CXCR1
45lactate459.0CAT, CRP, IL8, CD79A, CD40LG, TLR4
46histamine45 29 2411.0CD40LG, TLR2, IL8, TLR4, CD79A
47fibrinogen459.0CXCR2, CRP, CD40LG, TLR2, TLR4, CD79A
48alanine458.7CRP, CXCR2, CD79A, TLR4, TLR2, ALAS2
49vegf458.4CRP, CXCR2, CD79A, TLR4, CD40LG, IL8
50cysteine458.3CAT, TLR4, IL8, CXCR1, CXCR2, CD79A

GO Terms for genes affiliated with Bacteriuria

Sources:
16Gene Ontology
See all sources

Cellular components related to Bacteriuria according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Toll-like receptor 1-Toll-like receptor 2 protein complexGO:0353549.9TLR1, TLR2
2external side of plasma membraneGO:0098979.4CD79A, CD40LG, TLR2, TLR4
3integral to plasma membraneGO:0058877.8TLR4, TLR2, TLR1, CD40LG, PCDH8, CXCR2
4plasma membraneGO:0058866.4ADAM8, TIRAP, CAT, TLR4, TLR2, TLR5

Biological processes related to Bacteriuria according to GeneCards/GeneDecks:

(show all 34)
idNameGO IDScoreTop Affiliating Genes
1cellular response to triacyl bacterial lipopeptideGO:07172710.4TLR2, TLR1
2detection of triacyl bacterial lipopeptideGO:04249510.4TLR2, TLR1
3positive regulation of interleukin-6 biosynthetic processGO:04541010.4TIRAP, TLR1
4detection of diacyl bacterial lipopeptideGO:04249610.4TLR2, TLR1
5cellular response to bacterial lipopeptideGO:07122110.4TIRAP, TLR2
6regulation of cytokine secretionGO:05070710.3TLR4, TLR1
7positive regulation of toll-like receptor signaling pathwayGO:03412310.3TLR5, TLR2
8macrophage activationGO:04211610.3TLR1, TLR4
9positive regulation of macrophage cytokine productionGO:06090710.3TLR4, TLR2
10negative regulation of interleukin-17 productionGO:03270010.2TLR2, TLR4
11positive regulation of tumor necrosis factor biosynthetic processGO:04253510.2TLR4, TLR2, TLR1
12cellular response to lipoteichoic acidGO:07122310.2TLR2, TLR4, TIRAP
13positive regulation of tumor necrosis factor productionGO:03276010.1TIRAP, TLR4, TLR2
14I-kappaB phosphorylationGO:00725210.1TLR2, TLR4
15positive regulation of nitric-oxide synthase biosynthetic processGO:05177010.1TLR2, TLR4
16interleukin-8-mediated signaling pathwayGO:03811210.1CXCR2, CXCR1
17defense response to Gram-positive bacteriumGO:05083010.0TIRAP, TLR2, CRP
18toll-like receptor TLR6:TLR2 signaling pathwayGO:03812410.0TIRAP, TLR4, TLR2
19toll-like receptor TLR1:TLR2 signaling pathwayGO:03812310.0TIRAP, TLR4, TLR2
20B cell proliferationGO:04210010.0CD40LG, CD79A
21toll-like receptor 2 signaling pathwayGO:03413410.0TLR2, TLR4, TIRAP
22positive regulation of interleukin-8 productionGO:03275710.0TIRAP, TLR4, TLR2, TLR5
23T-helper 1 type immune responseGO:04208810.0TLR1, TLR4
24toll-like receptor signaling pathwayGO:0022249.9TLR5, TLR2, TLR4, TIRAP
25positive regulation of interleukin-12 productionGO:0327359.9CD40LG, TLR2, TLR4, TIRAP
26cellular defense responseGO:0069689.9CXCR2, PRF1, UMOD
27neutrophil activationGO:0421199.8CXCR2, IL8
28toll-like receptor 4 signaling pathwayGO:0341429.8TLR2, TLR4, TIRAP
29MyD88-dependent toll-like receptor signaling pathwayGO:0027559.8TIRAP, TLR4, TLR2, TLR5, TLR1
30receptor internalizationGO:0316239.8IL8, CXCR1, CXCR2
31dendritic cell chemotaxisGO:0024079.4CXCR2, CXCR1
32positive regulation of NF-kappaB transcription factor activityGO:0510929.4TIRAP, CAT, TLR4, TLR2, ADAM8
33innate immune responseGO:0450879.4TLR1, TLR5, TLR2, TLR4, TIRAP
34inflammatory responseGO:0069547.9ADAM8, TIRAP, TLR2, TLR5, TLR1, CRP

Molecular functions related to Bacteriuria according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide receptor activityGO:00187510.0TLR2, TLR4
2interleukin-8 receptor activityGO:0049189.6CXCR2, CXCR1
3transmembrane signaling receptor activityGO:0048889.5CD79A, TLR1, TLR2, TLR4
4interleukin-8 bindingGO:0199599.4CXCR1, CXCR2

Products for genes affiliated with Bacteriuria

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Bacteriuria

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet