Aliases & Classifications for Bagassosis

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Bagassosis, Aliases & Descriptions:

Name: Bagassosis 9 60
 
Sugar Cane Worker Pneumonitis 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology9 DOID:12522
MeSH33 D011009
NCIt38 C34409
SNOMED-CT55 67242002
ICD9CM27 495.1
ICD1025 J67.1

Summaries for Bagassosis

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Disease Ontology:9 An extrinsic allergic alveolitis that is an industrial disease characterized by cough, difficult breathing, chills, fever, and prolonged weakness caused by the inhalation of the dust of bagasse containing thermophilic actinomycetes.

MalaCards based summary: Bagassosis, also known as sugar cane worker pneumonitis, is related to intervertebral disc disease and muckle-wells syndrome. An important gene associated with Bagassosis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are Cellular roles of Anthrax toxin and LDL Oxidation in Atherogenesis. The compounds rantes and toxin-1 have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and skin, and related mouse phenotypes are tumorigenesis and immune system.

Wikipedia:63 Bagassosis, an interstitial lung disease, is a type of hypersensitivity pneumonitis attributed to... more...

Related Diseases for Bagassosis

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Diseases related to Bagassosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1intervertebral disc disease10.4IL1B
2muckle-wells syndrome10.4IL1B
3sinusitis10.4IL5
4pulmonary function10.4
5leishmaniasis10.4IL5
6crohn's disease10.3TNF
7silicosis10.2
8blau syndrome10.2TNF, IL1B
9aids dementia complex10.2TNF, IL1B
10familial mediterranean fever, ar10.2TNF, IL1B
11pulmonary eosinophilia10.2IL5, IL8
12interstitial lung disease10.2TNF, IL1B
13psoriatic arthritis10.2IL1B, TNF
14malaria10.2IL1B, TNF
15vernal keratoconjunctivitis10.2IL5, IL8
16toxic shock syndrome10.2IL1B, TNF
17bronchitis10.1IL8, IL5
18bacterial vaginosis10.1IL8, IL1B
19bronchiolitis10.1IL5, IL8
20acute respiratory distress syndrome10.1TNF, IL8
21bacterial meningitis10.1IL1B, IL8
22alcoholic hepatitis10.1TNF, IL8
23mastitis10.1IL1B, IL8
24periodontitis10.1IL1B, IL8
25rhinitis10.1IL5, IL8
26arthropathy10.1IL1B, TNF
27behcet's disease10.1IL8, TNF
28periodontal disease10.1IL6, TNF
29euthyroid sick syndrome10.1IL1B, IL6
30poems syndrome10.1IL1B, IL6
31lung cancer10.1
32byssinosis10.1
33pulmonary disease, chronic obstructive10.0IL6, IL1B
34eosinophilia10.0IL8, IL5
35pulmonary fibrosis, idiopathic10.0IL8, IL1B
36gastritis10.0IL1B, IL8
37eye disease10.0IL1B, IL6
38viral meningitis10.0IL6, IL8
39allergic rhinitis10.0IL8, IL5
40juvenile rheumatoid arthritis10.0TNF, IL6
41thrombocytosis10.0IL1B, IL6
42acquired immunodeficiency syndrome10.0IL6, IL1B
43allergic asthma10.0IL8, IL5
44connective tissue disease10.0TNF, IL6
45brain disease10.0IL1B, IL6
46atopic dermatitis10.0TNF, IL5, IL8
47skin disease10.0TNF, IL5, IL8
48pulmonary fibrosis9.9IL1B, IL8
49acute pancreatitis9.9IL6, IL8
50pancreatitis9.9IL6, IL1B

Graphical network of the top 20 diseases related to Bagassosis:



Diseases related to bagassosis

Symptoms for Bagassosis

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Drugs & Therapeutics for Bagassosis

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Drug clinical trials:

Search ClinicalTrials for Bagassosis

Search NIH Clinical Center for Bagassosis

Genetic Tests for Bagassosis

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Anatomical Context for Bagassosis

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MalaCards organs/tissues related to Bagassosis:

31
Lung, Liver, Skin

Animal Models for Bagassosis or affiliated genes

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MGI Mouse Phenotypes related to Bagassosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020067.9TNF, IL5, IL6, IL1B
2MP:00053877.5IL1B, IL6, IL8, IL5, TNF
3MP:00053977.4IL1B, IL6, IL8, IL5, TNF

Publications for Bagassosis

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Articles related to Bagassosis:

(show all 44)
idTitleAuthorsYear
1
Differences in cellular and inflammatory cytokine profiles in the bronchoalveolar lavage fluid in bagassosis and silicosis. (15376226)
2004
2
Hypersensitivity pneumonitis: bagassosis. (7807612)
1994
3
Recent trends in bagassosis in Japan. (1637710)
1992
4
Clinical, epidemiological, and laboratory criteria for the diagnosis of bagassosis. (2305800)
1990
5
Experimental bagassosis: role of infection. (6884291)
1983
6
Pathophysiological disturbances in bagassosis and bagasse workers. (7116010)
1982
7
Elimination of bagassosis in Louisiana paper manufacturing plant workers. (627039)
1978
8
Bagassosis: a report of 8 cases. (4424270)
1974
9
Bagassosis: a histopathologic study of pulmonary biopsies from six cases. (4712724)
1973
10
Pulmonary function at rest and during exercise following bagassosis. (4995433)
1971
11
Sequential observations on pulmonary functional derangements in Bagassosis. (5111660)
1971
12
Thermoactinomyces sacchari sp. nov., a thermophilic actinomycete causing bagassosis. (4999215)
1971
13
Prevention of bagassosis by addition of propionic acid to sugar cane waste. (5201841)
1970
14
Bagassosis. (A case report). (5456139)
1970
15
Bagassosis. IV. Precipitins against extracts of thermophilic actinomycetes in patients with bagassosis. (4182997)
1969
16
Bagassosis: an epidemiological, environmental, and clinical survey. (5723350)
1968
17
Bagassosis. (4170904)
1968
18
Pulmonary function in bagassosis. (5673109)
1968
19
Immunological aspects of bagassosis. (4972748)
1968
20
Bagassosis. (5609030)
1967
21
Bagassosis II. Skin reactivity to crude bagasse extracts and atopic status of patients. (4960059)
1967
22
Bagassosis: a study of pulmonary function in 20 cases. (23841194)
1966
23
Bagassosis: I. Precipitins against extracts of crude bagasse in the serum of patients. (23841195)
1966
24
THE RESURGENCE OF BAGASSOSIS IN LOUISIANA. (14218625)
1964
25
Bagassosis. (13997509)
1963
26
Glycogen metabolism of guinea-pig in experimental bagassosis. (13913344)
1962
27
Bagassosis and silicosis in the Philippines. (14028138)
1962
28
Bagassosis: a true pnemoconiosis. (13874417)
1962
29
Metastasizing lung cancer associated with past bagassosis. (13940182)
1962
30
In vitro studies on the utilization of glucose-1-14C by guinea-pig lungs in experimental bagassosis. (13977669)
1962
31
A study of tissue respiration & respiratory enzymes of guinea-pig liver in experimental bagassosis. (14039305)
1962
32
Cellular constituents of guinea-pig lungs in experimental bagassosis. (13913343)
1962
33
The glycolytic enzymes of guinea-pig lung in experimental bagassosis. (16748890)
1961
34
Experimental bagassosis. I. Enzymes of the lung in vivo. (14447107)
1960
35
Bagassosis-a medical enigma. (13805673)
1960
36
Experimental bagassosis. II. Enzymes of lung in vitro. (14447108)
1960
37
Bagassosis; a review, with further historical data, studies of pulmonary function, and results of adrenal steroid therapy. (13559276)
1958
38
Early bagassosis. (13233534)
1955
39
Bagassosis. (13263628)
1955
40
Aerobacter cloacae endotoxin as a possible factor in the etiology of bagassosis. (18873565)
1948
41
Aerobacter cloacae as a possible factor in the etiology of bagassosis. (20987049)
1946
42
Byssinosis and Bagassosis. (20784632)
1943
43
Four Cases of Bagassosis. (20784538)
1942
44
Bagassosis: An Industrial Lung Disease. (20784500)
1942

Variations for Bagassosis

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Expression for genes affiliated with Bagassosis

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Search GEO for disease gene expression data for Bagassosis.

Pathways for genes affiliated with Bagassosis

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Pathways related to Bagassosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4TNF, IL1B
29.4IL1B, TNF
3
Show member pathways
Serotonin Transporter Activity36
9.4TNF, IL1B
49.3TNF, IL8
59.1IL1B, IL6
69.0IL6, IL8
7
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
8.9TNF, IL5, IL8
88.8TNF, IL8, IL1B
98.7IL1B, IL6, IL5
10
Show member pathways
8.7IL1B, IL6, IL5
11
Show member pathways
8.7IL1B, IL6, IL5
12
Show member pathways
thioredoxin pathway36
8.6IL1B, IL6, TNF
138.6TNF, IL6, IL1B
14
Show member pathways
IL27-mediated signaling events36
8.6TNF, IL6, IL1B
158.6IL1B, IL6, TNF
16
Show member pathways
8.6TNF, IL6, IL1B
178.6TNF, IL6, IL1B
18
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
8.6TNF, IL6, IL1B
198.6TNF, IL6, IL1B
208.6TNF, IL6, IL1B
218.6IL5, IL8, IL6
228.5IL1B, IL6, IL8
23
Show member pathways
8.5IL1B, IL6, IL8
248.5IL6, IL8, TNF
25
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.2TNF, IL5, IL6, IL1B
268.2TNF, IL5, IL6, IL1B
27
Show member pathways
8.2TNF, IL5, IL6, IL1B
288.2IL1B, IL6, IL5, TNF
29
Show member pathways
8.2IL1B, IL6, IL5, TNF
308.0TNF, IL8, IL6, IL1B
31
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
8.0TNF, IL8, IL6, IL1B
32
Show member pathways
Immune response MIF in innate immunity response58
8.0TNF, IL8, IL6, IL1B
33
Show member pathways
8.0TNF, IL8, IL6, IL1B
34
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
8.0TNF, IL8, IL6, IL1B
358.0TNF, IL8, IL6, IL1B
368.0TNF, IL8, IL6, IL1B
37
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.0TNF, IL8, IL6, IL1B
388.0TNF, IL8, IL6, IL1B
398.0TNF, IL8, IL6, IL1B
408.0TNF, IL8, IL6, IL1B
418.0IL1B, IL6, IL8, TNF
42
Show member pathways
8.0IL1B, IL6, IL8, TNF
43
Show member pathways
8.0IL1B, IL6, IL8, TNF
44
Show member pathways
7.5TNF, IL5, IL8, IL6, IL1B
457.5IL1B, IL6, IL8, IL5, TNF
46
Show member pathways
7.5TNF, IL5, IL8, IL6, IL1B
47
Show member pathways
7.5TNF, IL5, IL8, IL6, IL1B
48
Show member pathways
7.5TNF, IL5, IL8, IL6, IL1B
49
Show member pathways
7.5TNF, IL5, IL8, IL6, IL1B

Compounds for genes affiliated with Bagassosis

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Compounds related to Bagassosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 155)
idCompoundScoreTop Affiliating Genes
1rantes439.3IL5, IL1B, IL8
2toxin-1438.9TNF, IL8, IL1B
3tenidap43 289.9IL1B, TNF, IL6
4anakinra43 129.9IL6, IL1B, TNF
5gold sodium thiomalate438.9TNF, IL8, IL1B
6vesnarinone438.9TNF, IL6, IL1B
7mcp 1438.8IL5, IL8, IL6
8budesonide43 49 1210.8IL1B, TNF, IL5, IL8
9fluticasone propionate43 49 59 1211.8IL1B, IL5, TNF, IL8
10gabexate mesilate438.7IL8, IL6, TNF
11ulinastatin438.7TNF, IL6, IL8
12hbd2438.7IL1B, IL8, IL6
13ivig438.5IL6, TNF, IL5, IL1B
14imiquimod43 59 28 1211.5IL5, IL8, IL6, TNF
15thalidomide43 49 59 1211.5IL1B, TNF, IL5, IL6
16taurine chloramine438.4IL8, IL1B, IL6, TNF
17mip 1alpha438.4IL1B, TNF, IL6, IL8
18tpck438.4TNF, IL8, IL1B, IL6
19polymyxin b438.4IL8, IL6, IL1B, TNF
20groalpha438.4TNF, IL8, IL6, IL1B
21triptolide438.4IL1B, IL6, IL8, TNF
22ciglitazone43 289.4TNF, IL8, IL6, IL1B
23lipoteichoic acid438.4IL1B, IL8, TNF, IL6
24etanercept43 49 1210.4TNF, IL1B, IL6, IL8
25peptidoglycan43 289.4IL8, TNF, IL1B, IL6
26pentoxifylline43 129.4TNF, IL8, IL6, IL1B
27fmlp438.4IL1B, IL8, TNF, IL5
28ccl343 289.3IL6, IL1B, IL8, TNF
29neopterin438.3IL1B, IL6, IL8, TNF
3015-deoxy-delta-12,14-prostaglandin j2438.3IL8, IL6, IL1B, TNF
31pdtc438.3IL8, TNF, IL6, IL1B
32sp 60012543 599.3IL1B, IL6, IL8, TNF
33troglitazone43 28 59 1211.2IL6, IL1B, IL8, TNF
34endotoxin438.0IL8, TNF, IL6, IL1B
35il-12438.0TNF, IL1B, IL6, IL8, IL5
36gm-csf43 289.0IL1B, IL5, IL8, TNF, IL6
37polyinosinic-polycytidylic acid438.0IL8, IL1B, IL6, IL5, TNF
38poly(i-c)438.0TNF, IL5, IL8, IL6, IL1B
39il 10438.0TNF, IL5, IL1B, IL6, IL8
40leukotriene b443 59 2410.0IL1B, IL6, IL8, IL5, TNF
41hydrocortisone43 2 59 1211.0IL6, IL1B, IL5, TNF, IL8
42herbimycin a43 599.0TNF, IL5, IL8, IL6, IL1B
43sb 20358043 598.9IL5, IL1B, IL6, IL8, TNF
44histamine43 28 249.9IL8, IL5, IL6, IL1B, TNF
45ly294002437.9IL8, TNF, IL5, IL1B, IL6
46genistein43 28 59 2 24 1212.9IL1B, IL6, IL5, TNF, IL8
47pge2437.9TNF, IL5, IL8, IL6, IL1B
48cycloheximide437.8IL6, IL1B, IL8, IL5, TNF
49curcumin437.7IL1B, TNF, IL8, IL6
50dexamethasone43 49 28 1210.4TNF, IL5, IL8, IL6, IL1B

GO Terms for genes affiliated with Bagassosis

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Cellular components related to Bagassosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.5IL5, IL8, IL6, IL1B, TNF
2extracellular spaceGO:00056157.2IL1B, IL6, IL8, IL5, TNF

Biological processes related to Bagassosis according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of podosome assemblyGO:00718039.9TNF, IL5
2sequestering of triglycerideGO:00307309.9IL1B, TNF
3positive regulation of calcidiol 1-monooxygenase activityGO:00605599.9IL1B, TNF
4positive regulation of heterotypic cell-cell adhesionGO:00341169.9TNF, IL1B
5positive regulation of fever generationGO:00316229.9TNF, IL1B
6positive regulation of chemokine biosynthetic processGO:00450809.8TNF, IL1B
7regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.8IL1B, TNF
8positive regulation of membrane protein ectodomain proteolysisGO:00510449.8IL1B, TNF
9negative regulation of lipid catabolic processGO:00509959.8TNF, IL1B
10positive regulation of NF-kappaB import into nucleusGO:00423469.8IL1B, TNF
11lipopolysaccharide-mediated signaling pathwayGO:00316639.8IL1B, TNF
12positive regulation of mitosisGO:00458409.8IL1B, TNF
13protein kinase B signalingGO:00434919.8IL1B, TNF
14negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:020012409.8IL1B, TNF
15cellular response to organic cyclic compoundGO:00714079.8TNF, IL1B
16positive regulation of interferon-gamma productionGO:00327299.8IL1B, TNF
17embryonic digestive tract developmentGO:00485669.7IL8, TNF
18positive regulation of JNK cascadeGO:00463309.7IL1B, TNF
19neutrophil chemotaxisGO:00305939.6IL8, IL1B
20calcium-mediated signalingGO:00197229.6IL8, TNF
21MAPK cascadeGO:00001659.6IL1B, TNF
22positive regulation of immunoglobulin secretionGO:00510249.6IL5, IL6
23positive regulation of JAK-STAT cascadeGO:00464279.6IL5, IL6
24epithelial cell proliferation involved in salivary gland morphogenesisGO:00606649.6TNF, IL6
25negative regulation of lipid storageGO:00108889.5TNF, IL6
26positive regulation of chemokine productionGO:00327229.5IL6, TNF
27regulation of insulin secretionGO:00507969.5IL1B, TNF
28defense response to Gram-positive bacteriumGO:00508309.5TNF, IL6
29negative regulation of fat cell differentiationGO:00455999.5IL6, TNF
30positive regulation of protein phosphorylationGO:00019349.4IL1B, TNF
31positive regulation of smooth muscle cell proliferationGO:00486619.4IL6, TNF
32positive regulation of T cell proliferationGO:00421029.4IL6, IL1B
33positive regulation of peptidyl-serine phosphorylationGO:00331389.4IL6, TNF
34response to mechanical stimulusGO:00096129.4IL6, TNF
35positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4IL6, IL5
36humoral immune responseGO:00069599.4TNF, IL6
37activation of MAPK activityGO:00001879.3IL1B, TNF
38positive regulation of protein kinase B signalingGO:00518979.3TNF, IL6
39response to glucocorticoidGO:00513849.2IL6, TNF
40immune responseGO:00069559.2IL5, IL8, IL1B
41cytokine-mediated signaling pathwayGO:00192219.1IL5, IL6, IL1B
42positive regulation of nitric oxide biosynthetic processGO:00454299.1IL1B, IL6, TNF
43positive regulation of interleukin-6 productionGO:00327559.1TNF, IL6, IL1B
44positive regulation of NF-kappaB transcription factor activityGO:00510929.0IL1B, IL6, TNF
45positive regulation of ERK1 and ERK2 cascadeGO:00703748.8IL6, TNF
46positive regulation of transcription from RNA polymerase II promoterGO:00459448.6TNF, IL6, IL1B
47positive regulation of sequence-specific DNA binding transcription factor activityGO:00510918.6TNF, IL5, IL6, IL1B
48positive regulation of transcription, DNA-templatedGO:00458938.6TNF, IL5, IL6, IL1B
49negative regulation of cell proliferationGO:00082858.4TNF, IL8, IL6, IL1B
50inflammatory responseGO:00069548.0IL1B, IL6, IL8, IL5, TNF

Molecular functions related to Bagassosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.2IL1B, IL6, IL5, TNF

Products for genes affiliated with Bagassosis

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Sources for Bagassosis

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3CDC
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25ICD10
26ICD10 via Orphanet
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29KEGG
33MeSH
34MESH via Orphanet
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56SNOMED-CT via Orphanet
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