MCID: BLN010
MIFTS: 38

Balanitis malady

Reproductive category

Summaries for Balanitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Balanitis (/bæləˈnaɪtɪs/; from Greek: βάλανος balanos \"acorn\") is inflammation of the... more...

MalaCards: Balanitis is related to balanitis xerotica obliterans and squamous cell carcinoma. An important gene associated with Balanitis is SRR (serine racemase), and among its related pathways is Regulation of Insulin Secretion. The compounds n-acetyllactosamine and amide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, skin and t cells.

Aliases & Classifications for Balanitis

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH, 25ICD10
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Related Diseases for Balanitis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Balanitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 48)
idRelated DiseaseScoreTop Affiliating Genes
1balanitis xerotica obliterans31.3AKTIP
2squamous cell carcinoma30.3IFI27, ISG20, GAL, MLXIPL, MT-CO2, LGALS3
3lichen sclerosus10.4
4balanoposthitis10.3
5vulvitis10.2
6urethral stricture10.2
7hypospadias10.2
8verrucous carcinoma10.2
9necrobiosis lipoidica10.1
10syphilis10.1
11herpes simplex10.0ISG20, GGH
12hepatitis10.0GAL
13colon cancer10.0IFI27, LGALS3, GAL
14mood disorder10.0GGH, GAL, ADRA2A
15neuroendocrine tumor10.0IFI27, GAL, GGH
16diabetes mellitus10.0MLXIPL
17leukemia10.0MLXIPL, IFI27, GGH, ISG20, CTRL, GAL
18adenoma10.0PVR, PTGIS, GGH, GAL, IFI27, LGALS3
19ischemia10.0GAL, PTGIS, LGALS3
20breast cancer10.0LGALS3, MLXIPL, GAL, CTRL, ISG20, IFI27
21adenocarcinoma10.0IFI27, MLXIPL, GAL, PTGIS, LGALS3, ADRA2A
22ipex syndrome10.0GGH, GAL, CTRL, ISG20, PVR
23alzheimer's disease10.0SRR, GAL, CTRL
24glioblastoma multiforme10.0SRR, LGALS3, IFI27
25melanoma10.0LGALS3, GAL, CTRL, ISG20, IFI27
26burkitt's lymphoma10.0GGH, MLXIPL, ISG20, IFI27, LGALS3
27pituitary adenoma10.0IFI27, GAL, LGALS3
28paronychia9.9
29proctitis9.9
30vulvovaginitis9.9
31cicatricial pemphigoid9.9
32pemphigus9.9
33lichen planus9.9
34reactive arthritis9.9
35gonorrhea9.9
36peyronie's disease9.9
37primary syphilis9.9
38adenosquamous carcinoma9.9
39verrucous papilloma9.9
40acute conjunctivitis9.9
41arthritis9.9
42stomatitis9.9
43telangiectasis9.9
44uveitis9.9
45vaginitis9.9
46keratoderma9.9
47atopy9.9
48pemphigus vegetans9.9

Graphical network of the top 20 diseases related to Balanitis:



Diseases related to balanitis

Clinical Features for Balanitis

Drugs & Therapeutics for Balanitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Balanitis

Anatomical Context for Balanitis

Sources:
33MalaCards
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MalaCards organs/tissues related to Balanitis:

33
Bone marrow, Skin, T cells, B cells

Animal Models for Balanitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Balanitis

Sources:
51PubMed
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Articles related to Balanitis:

(show top 50)    (show all 258)
idTitleAuthorsYear
1
Balanitis xerotica obliterans in children and adolescents: A literature review and clinical series. (24295833)
2013
2
Circumcision as treatment for Zoon's balanitis in an HIV-positive teenage patient. (23970603)
2013
3
Pseudoepitheliomatous keratotic and micaceous balanitis. (24339464)
2013
4
High prevalence and resistance rates to antibiotics in anaerobic bacteria in specimens from patients with chronic balanitis. (22710106)
2012
5
Paediatric balanitis xerotica obliterans: an 8-year experience. (22649954)
2012
6
Balanitis xerotica obliterans in children and its incidence under the age of 5 years. (21705275)
2012
7
Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans. (22613322)
2012
8
Foreskin preputioplasty and intralesional triamcinolone: a valid alternative to circumcision for balanitis xerotica obliterans. (22498393)
2012
9
Direct impression on agar surface as a diagnostic sampling procedure for candida balanitis. (19841002)
2010
10
Candida balanitis: risk factors. (20002652)
2010
11
Pseudoepitheliomatous, keratotic and micaceous balanitis after penile squamous cell carcinoma. (20456408)
2010
12
Tacrolimus therapy for circinate balanitis associated with reactive arthritis. (19955992)
2009
13
Zoon's Balanitis: Benign or Premalignant Lesion? (20652106)
2009
14
Erythroplasia of Queyrat of the glans penis on a background of Zoon's plasma cell balanitis. (18412812)
2008
15
Balanitis with eczematous perigenital intertriginous candidosis. (18783569)
2008
16
Plasma cell balanitis treated with tacrolimus 0.1%. (16307659)
2005
17
Plasma cell balanitis of Zoon treated successfully with topical tacrolimus. (16045706)
2005
18
Emergency dorsal slit for balanitis with retention. (15056750)
2004
19
Topical tacrolimus: an effective therapy for Zoon balanitis. (15611442)
2004
20
Zoon plasma cell balanitis: an overview and role of histopathology. (15588560)
2004
21
Balanitis xerotica obliterans: epidemiologic distribution in an equal access health care system. (12602705)
2003
22
Zoon's balanitis treated with Erbium:YAG laser ablation. (11870791)
2002
23
Long-term antibiotic therapy for balanitis xerotica obliterans. (9922014)
1999
24
Desquamative gingivitis and balanitis--linear IgA disease or cicatricial pemphigoid? (9894362)
1998
25
Full-thickness skin grafts from eyelids to penis, plus split-thickness grafts in chronic balanitis xerotica obliterans. (9043588)
1997
26
Bacillus Calmette-Guerin (BCG) balanitis as a complication of intravesical BCG immunotherapy: a case report. (7591595)
1995
27
Vitamin A derivatives and HPV balanitis. (7632285)
1995
28
Clinical features and management of recurrent balanitis; association with atopy and genital washing. (8244363)
1993
29
An argument for circumcision. Prevention of balanitis in the adult. (2383029)
1990
30
Lichen aureus of the glans penis as an expression of Zoon's balanitis. (2808800)
1989
31
The treatment of Zoon's balanitis with the carbon dioxide laser. (2497162)
1989
32
Balanitis xerotica obliterans: surgical treatment. (3360038)
1988
33
Persistent bullae on the penis of an elderly man. Balanitis xerotica obliterans. (3662575)
1987
34
Pseudoepitheliomatous, keratotic, and micaceous balanitis. (3967518)
1985
35
Zoon's balanitis treated by circumcision. (6747077)
1984
36
Subpreputial carriage of aerobic micro-organisms and balanitis. (6338999)
1983
37
Continuous wave carbon dioxide treatment of balanitis xerotica obliterans. (6805123)
1982
38
Keratotic and micaceous pseudoepitheliomatous balanitis. (7116112)
1982
39
Zoon's balanitis (balanitis circumscripta plasmacellularis). (7284248)
1981
40
Balanitis xerotica obliterans. (465992)
1979
41
Amebic balanitis. (201784)
1978
42
Balanitis xerotica obliterans in children. (1237636)
1975
43
Plasma cell balanitis. (4664561)
1972
44
Balanitis due to fixed drug eruption associated with tetracycline therapy. (4251608)
1971
45
Clinical evaluation of carbenoxolone in balanitis. (4933123)
1971
46
Balanitis xerotica obliterans. (15407359)
1949
47
Balanitis xerotica obliterans. (18098689)
1948
48
Balanitis xerotica obliterans; a report of two cases. (20290779)
1947
49
Balanitis xerotica obliterans. (20262884)
1947
50
Treatment of Fusospirillary Balanitis. (20785082)
1943

Genetic Variations for Balanitis

Expression for genes affiliated with Balanitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Balanitis

Search GEO for disease gene expression data for Balanitis.

Pathways for genes affiliated with Balanitis

Sources:
54Reactome
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Pathways related to Balanitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.4ADRA2A, PLCB2, MLXIPL

Compounds for genes affiliated with Balanitis

Sources:
45Novoseek, 24HMDB, 11DrugBank, 50PharmGKB
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Compounds related to Balanitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1n-acetyllactosamine45 2411.6LGALS3, MLXIPL, GAL
2amide4510.6LGALS3, MLXIPL, GAL, CTRL
3lactose45 1111.6GAL, MLXIPL, LGALS3
4gal(beta1-3)galnac4510.5LGALS3, GAL
5polyacrylamide4510.5LGALS3, MLXIPL, CTRL, GAL
6estrogen4510.4ADRA2A, ISG20, PHB2
7lipid4510.4MLXIPL, GGH, IFI27, LGALS3, ADRA2A, GAL
8tyrosine4510.4CTRL, GAL, LGALS3, ISG20, IFI27, ITFG1
9mirtazapine50 45 1112.3GAL, ADRA2A
10phosphatidylinositol4510.3LGALS3, CTRL, PLCB2, IFI27, GAL
11calcium45 50 11 2413.2ADRA2A, LGALS3, SRR, MLXIPL, GAL, CTRL
12phosphoinositide4510.0LGALS3, PLCB2, GAL, IFI27

GO Terms for genes affiliated with Balanitis

Sources:
16Gene Ontology
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Cellular components related to Balanitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00573710.1ADRA2A, ISG20, AKTIP, MLXIPL, MINK1, SIAH2

Products for genes affiliated with Balanitis

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Sources for Balanitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet