MCID: BLN010
MIFTS: 40

Balanitis malady

Reproductive diseases category

Summaries for Balanitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Balanitis (/bæləˈnaɪtɪs/; from Greek: βάλανος balanos \"acorn\") is inflammation of the... more...

MalaCards: Balanitis is related to balanitis xerotica obliterans and squamous cell carcinoma. An important gene associated with Balanitis is SRR (serine racemase), and among its related pathways is Regulation of Insulin Secretion. The compounds n-acetyllactosamine and amide have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and bone.

Aliases & Classifications for Balanitis

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Related Diseases for Balanitis

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17GeneCards, 18GeneDecks
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Diseases related to Balanitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1balanitis xerotica obliterans31.3AKTIP
2squamous cell carcinoma30.3IFI27, ISG20, GAL, MLXIPL, MT-CO2, LGALS3
3herpes simplex30.0ISG20, GGH
4urethritis10.3
5balanoposthitis10.3
6vulvitis10.2
7phimosis10.2
8urethral stricture10.2
9hypospadias10.1
10verrucous carcinoma10.1
11necrobiosis lipoidica10.0
12syphilis10.0
13hepatitis10.0GAL
14colon cancer10.0IFI27, LGALS3, GAL
15mood disorder10.0GGH, GAL, ADRA2A
16neuroendocrine tumor10.0IFI27, GAL, GGH
17diabetes mellitus10.0MLXIPL
18leukemia10.0MLXIPL, IFI27, GGH, ISG20, CTRL, GAL
19adenoma10.0PVR, PTGIS, GGH, GAL, IFI27, LGALS3
20ischemia10.0GAL, PTGIS, LGALS3
21breast cancer10.0LGALS3, MLXIPL, GAL, CTRL, ISG20, IFI27
22adenocarcinoma10.0IFI27, MLXIPL, GAL, PTGIS, LGALS3, ADRA2A
23ipex syndrome10.0GGH, GAL, CTRL, ISG20, PVR
24alzheimer's disease10.0SRR, GAL, CTRL
25glioblastoma multiforme10.0SRR, LGALS3, IFI27
26melanoma10.0LGALS3, GAL, CTRL, ISG20, IFI27
27burkitt's lymphoma10.0GGH, MLXIPL, ISG20, IFI27, LGALS3
28pituitary adenoma10.0IFI27, GAL, LGALS3
29paronychia9.9
30proctitis9.9
31vulvovaginitis9.9
32cicatricial pemphigoid9.9
33pemphigus9.9
34lichen planus9.9
35reactive arthritis9.9
36gonorrhea9.9
37peyronie's disease9.9
38primary syphilis9.9
39adenosquamous carcinoma9.9
40acute conjunctivitis9.9
41arthritis9.9
42conjunctivitis9.9
43cystitis9.9
44fibrosarcoma9.9
45gingival disease9.9
46gingivitis9.9
47hyperglycemia9.9
48in situ carcinoma9.9
49leprosy9.9
50penis squamous cell carcinoma9.9

Graphical network of the top 20 diseases related to Balanitis:



Diseases related to balanitis

Clinical Features for Balanitis

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Drugs & Therapeutics for Balanitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Balanitis

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Anatomical Context for Balanitis

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32MalaCards
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MalaCards organs/tissues related to Balanitis:

32
Skin, Bone marrow, Bone, T cells

Animal Models for Balanitis or affiliated genes

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Publications for Balanitis

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50PubMed
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Articles related to Balanitis:

(show top 50)    (show all 258)
idTitleAuthorsYear
1
Intralesional adalimumab for the treatment of refractory balanitis xerotica obliterans. (23324752)
2013
2
Plasma cell balanitis presenting in a patient with a history of syphilis. (21992223)
2012
3
Skin phototype and local trauma in the onset of balanitis xerotica obliterans (BXO) in circumcised patients. (22210729)
2012
4
Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans. (21929920)
2011
5
Penile lichen sclerosus (balanitis xerotica obliterans). (22085120)
2011
6
Implantation dermoid and balanitis xerotica obliterans: rare complications after hypospadias repair: case gallery and review of relevant literature. (19360553)
2010
7
Extensive balanitis xerotica obliterans of urethrocutaneous fistula presenting as mass in scrotum. (19913886)
2010
8
Treatment of balanitis of Zoon's with tacrolimus 0.03% ointment. (21938121)
2009
9
Erythroplasia of Queyrat with Zoon's balanitis: a diagnostic dilemma. (19050221)
2008
10
Pseudoepitheliomatous, keratotic, and micaceous balanitis: case report and review of the literature. (18549127)
2008
11
Urethral reconstruction in balanitis xerotica obliterans. (18931544)
2008
12
Primary syphilis presenting as balanitis. (17623510)
2007
13
Extensive balanitis xerotica obliterans (BXO) involving the anterior urethra and scrotum. (17180441)
2006
14
Plasma cell balanitis: clinicopathologic study of 112 cases and treatment modalities. (17241566)
2006
15
A focus on differential diagnosis of lichen planus and plasma cell balanitis. (16836515)
2006
16
The response of clinical balanitis xerotica obliterans to the application of topical steroid-based creams. (16516649)
2006
17
Plasma cell balanitis treated with tacrolimus 0.1%. (16307659)
2005
18
In vitro antimicrobial susceptibility of Mycoplasma mycoides mycoides large colony and Arcanobacterium pyogenes isolated from clinical cases of ulcerative balanitis and vulvitis in Dorper sheep in South Africa. (16642716)
2005
19
High incidence of balanitis xerotica obliterans in boys with phimosis: prospective 10-year study. (16060864)
2005
20
'Watering-can penis' in pseudoepitheliomatous, keratotic and micaceous balanitis. (15339089)
2004
21
Zoon's balanitis: presentation of 15 patients, five treated with a carbon dioxide laser. (12694501)
2003
22
Balanitis xerotica obliterans: a form of lichen sclerosus. (12602704)
2003
23
Balanitis of Zoon: a clinicopathologic study of 45 cases. (12454596)
2002
24
The response of balanitis xerotica obliterans to local steroid application compared with placebo in children. (11125410)
2001
25
Bowen's disease of the glans penis (erythroplasia of Queyrat) in plasma cell balanitis. (10879310)
2000
26
Carcinoma of the penis preceded by Zoon's balanitis. (10639067)
1999
27
Balanitis xerotica obliterans in monozygotic twins. (9439431)
1997
28
Balanitis caused by group A beta-hemolytic streptococci. (8895932)
1996
29
Squamous cell carcinoma of the penis arising from balanitis xerotica obliterans. (8836794)
1996
30
Dermacase. Balanitis xerotica obliterans. (7950467)
1994
31
Composition of the inflammatory infiltrate in pediatric penile lichen sclerosus et atrophicus (balanitis xerotica obliterans): a prospective, comparative immunophenotyping study. (8008686)
1994
32
Recurrent bullous balanitis: an unusual presentation of balanitis xerotica obliterans. (8142531)
1994
33
Chronic balanitis with palisading granuloma: an atypical genital localization of necrobiosis lipoidica responsive to pentoxifylline. (8186513)
1994
34
Group A beta-hemolytic streptococcal balanitis: it may be more common than you think. (2057252)
1991
35
Pseudoepitheliomatous, keratotic, micaceous balanitis. A clinical lesion with two histologic subsets: hyperplastic dystrophy and verrucous carcinoma. (3343410)
1988
36
1% bifonazole cream in the treatment of Candida balanitis: a clinical trial. (3508602)
1987
37
Balanitis associated with hyperglycemia. (7050487)
1982
38
Necrotising balanitis due to a generalised primary infection with herpes simplex virus type 2. (427514)
1979
39
Balanitis xerotica obliterans involving anterior urethra. (516213)
1979
40
Amebic balanitis. (201784)
1978
41
Urethro-balanitis xerotica obliterans. (627227)
1978
42
Tumor conference No 18: squamous-cell carcinoma arising in balanitis xerotica obliterans. (690306)
1978
43
The treatment of balanitis xerotica obliterans with testosterone propionate ointment. (71837)
1977
44
Balanitis xerotica obliterans and urinary obstruction. (5095580)
1971
45
A virus associated with vulvitis and balanitis in the horse-- preliminary report. (4300973)
1968
46
Balanitis xerotica obliterans: effective treatment with topical and sublesional corticosteroids. (6058157)
1967
47
DEQUALINIUM: A POSSIBLE COMPLICATION OF ITS USE IN BALANITIS. (14172940)
1964
48
Acute monilial balanitis. (13712049)
1960
49
Balanitis xerotica obliterans. (13244849)
1955
50
Balanitis xerotica obliterans; a case report. (13152866)
1954

Genetic Variations for Balanitis

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Expression for genes affiliated with Balanitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Balanitis

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Pathways for genes affiliated with Balanitis

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53Reactome
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Pathways related to Balanitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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10.4ADRA2A, PLCB2, MLXIPL

Compounds for genes affiliated with Balanitis

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44Novoseek, 24HMDB, 11DrugBank, 49PharmGKB
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Compounds related to Balanitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1n-acetyllactosamine44 2411.6LGALS3, MLXIPL, GAL
2amide4410.6LGALS3, MLXIPL, GAL, CTRL
3lactose44 1111.6GAL, MLXIPL, LGALS3
4gal(beta1-3)galnac4410.5LGALS3, GAL
5polyacrylamide4410.5LGALS3, MLXIPL, CTRL, GAL
6estrogen4410.4ADRA2A, ISG20, PHB2
7lipid4410.4MLXIPL, GGH, IFI27, LGALS3, ADRA2A, GAL
8tyrosine4410.4CTRL, GAL, LGALS3, ISG20, IFI27, ITFG1
9mirtazapine49 44 1112.3GAL, ADRA2A
10phosphatidylinositol4410.3LGALS3, CTRL, PLCB2, IFI27, GAL
11calcium44 49 11 2413.2ADRA2A, LGALS3, SRR, MLXIPL, GAL, CTRL
12phosphoinositide4410.0LGALS3, PLCB2, GAL, IFI27

GO Terms for genes affiliated with Balanitis

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16Gene Ontology
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Cellular components related to Balanitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00573710.1ADRA2A, ISG20, AKTIP, MLXIPL, MINK1, SIAH2

Products for genes affiliated with Balanitis

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Sources for Balanitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet