MCID: BLN010
MIFTS: 33

Balanitis

Categories: Reproductive diseases

Aliases & Classifications for Balanitis

Summaries for Balanitis

MalaCards based summary : Balanitis is related to balanitis xerotica obliterans and lichen sclerosus. An important gene associated with Balanitis is TGM2 (Transglutaminase 2). The drugs Acetaminophen and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and bone, and related phenotype is behavior/neurological.

Wikipedia : 72 Balanitis is inflammation of the glans penis. When the foreskin is also affected, it is termed... more...

Related Diseases for Balanitis

Graphical network of the top 20 diseases related to Balanitis:



Diseases related to Balanitis

Symptoms & Phenotypes for Balanitis

MGI Mouse Phenotypes related to Balanitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.02 SLC5A2 TGM1 TGM2 TGM3 PHB2

Drugs & Therapeutics for Balanitis

Drugs for Balanitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 1 103-90-2 1983
2
Bupivacaine Approved, Investigational Phase 1 2180-92-9, 38396-39-3 2474
3
Ibuprofen Approved Phase 1 15687-27-1 3672
4
Ketorolac Approved Phase 1 74103-06-3, 66635-83-4 3826
5
Sevoflurane Approved, Vet_approved Phase 1 28523-86-6 5206
6 Anti-Infective Agents Phase 1
7 Analgesics Phase 1
8 Analgesics, Non-Narcotic Phase 1
9 Anesthetics Phase 1
10 Anesthetics, General Phase 1
11 Anesthetics, Inhalation Phase 1
12 Anesthetics, Local Phase 1
13 Anti-Inflammatory Agents Phase 1
14 Anti-Inflammatory Agents, Non-Steroidal Phase 1
15 Antipyretics Phase 1
16 Antirheumatic Agents Phase 1
17 Central Nervous System Depressants Phase 1
18 Cyclooxygenase Inhibitors Phase 1
19 Ketorolac Tromethamine Phase 1
20 Peripheral Nervous System Agents Phase 1
21 Platelet Aggregation Inhibitors Phase 1
22
Menthol Approved 2216-51-5 16666
23
Triamcinolone Approved, Vet_approved 124-94-7 31307
24
Adenosine Approved, Investigational 58-61-7 60961
25
Vitamin A Approved, Nutraceutical, Vet_approved 11103-57-4, 68-26-8 445354
26 glucocorticoids
27 Hormone Antagonists
28 Hormones
29 Hormones, Hormone Substitutes, and Hormone Antagonists
30 Immunosuppressive Agents
31 Retinol palmitate
32 triamcinolone acetonide
33 Triamcinolone diacetate
34 Triamcinolone hexacetonide
35 retinol Nutraceutical

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand Completed NCT00213057 Phase 1 Carraguard (PC-515)
2 Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision Recruiting NCT02973958 Phase 1 Bupivacaine;Sevoflurane;Acetaminophen;Ibuprofen;Ketorolac
3 Circumcision Versus Preputioplasty for BXO in Children Recruiting NCT02854995
4 Susceptibility Genes in Autism Spectrum Disorders Recruiting NCT02628808

Search NIH Clinical Center for Balanitis

Cochrane evidence based reviews: balanitis

Genetic Tests for Balanitis

Anatomical Context for Balanitis

MalaCards organs/tissues related to Balanitis:

39
Skin, T Cells, Bone, Bone Marrow

Publications for Balanitis

Articles related to Balanitis:

(show top 50) (show all 293)
id Title Authors Year
1
Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. ( 28382428 )
2017
2
Balanitis xerotica obliterans: has its diagnostic accuracy improved with time? ( 28620502 )
2017
3
A case of Zoon Balanitis in an immune-competent teenager. ( 28895662 )
2017
4
Pseudoepitheliomatous keratotic and micaceous balanitis treated with topical 5-fluorouracil and liquid nitrogen. ( 28406530 )
2017
5
Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature. ( 28892974 )
2017
6
Zoon's balanitis treated with topical tacrolimus. ( 28479782 )
2017
7
Zoon Balanitis Revisited: Report of Balanitis Circumscripta Plasmacellularis Resolving With Topical Mupirocin Ointment Monotherapy. ( 28301626 )
2017
8
Circinate Balanitis. ( 28076706 )
2017
9
Streptococcus pyogenes as the cause of vulvovaginitis and balanitis in children from Nis, Serbia. ( 27638252 )
2016
10
Recurrence after management of meatal balanitis xerotica obliterans. ( 28089110 )
2016
11
Reflectance confocal microscopy as a non-invasive complementary tool in the diagnosis of psoriatic balanitis. ( 27514619 )
2016
12
The clinical spectrum of syphilitic balanitis of Follmann: report of five cases and a review of the literature. ( 27421838 )
2016
13
Zoon balanitis: A comprehensive review. ( 27890945 )
2016
14
Bleeding after circumcision is more likely in children with lichen sclerosus (balanitis xerotica obliterans). ( 28043767 )
2016
15
Contact balanitis to tromantadine. ( 27757977 )
2016
16
Response to commentary to 'Bleeding after circumcision is more likely in children with Lichen Sclerosus (Balanitis Xerotica Obliterans)'. ( 28089293 )
2016
17
Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. ( 27649154 )
2016
18
Candida albicans and Streptococcus pyogenes balanitis: diabetes or STI? ( 26232734 )
2015
19
Circinate balanitis as the presenting symptom of sexually-acquired reactive arthritis: a case report. ( 25918330 )
2015
20
Balanitis is a risk factor for herpes zoster. ( 25596845 )
2015
21
Dermoscopy of Zoon's plasma cell balanitis. ( 26670716 )
2015
22
ZOON's BALANITIS SUCCESSFULLY TREATED WITH PHOTODYNAMIC THERAPY: CASE REPORT AND LITERATURE REVIEW. ( 26321748 )
2015
23
Reiter's disease: Circinate balanitis as alone preceding presentation - Successfully treated with pimecrolimus 1% cream. ( 26392659 )
2015
24
Pseudoepitheliomatous, Keratotic and Micaceous Balanitis: A Case Report. ( 26557598 )
2015
25
Therapeutic Efficacy of Topical Calcineurin Inhibitors in Plasma Cell Balanitis: Case Series and Review of the Literature. ( 24434685 )
2014
26
Treatment of pseudoepitheliomatous, keratotic, and micaceous balanitis with topical photodynamic therapy. ( 25266766 )
2014
27
Zoon's balanitis. ( 25763417 )
2014
28
Treatment of urethral strictures in balanitis xerotica obliterans (BXO) using circular buccal mucosal meatoplasy: experience of 15 cases. ( 24704927 )
2014
29
Meatal Stenosis in Boys following Circumcision for Lichen Sclerosus (Balanitis Xerotica Obliterans). ( 24992332 )
2014
30
Successful use of dapsone for the management of circinate balanitis. ( 24635073 )
2014
31
Approach to balanitis/balanoposthitis: Current guidelines. ( 26396455 )
2014
32
Pseudoepitheliomatous keratotic and micaceous balanitis of Civatte. ( 24860747 )
2014
33
Plasma cell (Zoon) balanitis: another inflammatory disorder that can be rich in IgG4+ plasma cells. ( 25216321 )
2014
34
Photodynamic therapy for Zoon balanitis. ( 25333228 )
2014
35
Dermoscopy in plasma cell balanitis: its usefulness in diagnosis and follow-up. ( 25176141 )
2014
36
Clinical study of the effectiveness of the A<water of the 3 sulfatesA> on balanitis and balanoposthitis. ( 25262388 )
2014
37
Granulomatous balanitis after intravesical Bacille Calmette-GuAcrin instillation. ( 23177394 )
2013
38
Intralesional adalimumab for the treatment of refractory balanitis xerotica obliterans. ( 23324752 )
2013
39
Balanitis xerotica obliterans in children and adolescents: A literature review and clinical series. ( 24295833 )
2013
40
Incidence of balanitis xerotica obliterans in boys younger than 10 years presenting with phimosis. ( 23296396 )
2013
41
Differentiation between balanitis and carcinoma in situ using reflectance confocal microscopy. ( 23325422 )
2013
42
Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis. ( 23356463 )
2013
43
Pseudoepitheliomatous keratotic and micaceous balanitis with malignant transformation. ( 23919054 )
2013
44
Pseudoepitheliomatous keratotic and micaceous balanitis. ( 24339464 )
2013
45
Syphilitic balanitis of Follmann. ( 24134463 )
2013
46
Circumcision as treatment for Zoon's balanitis in an HIV-positive teenage patient. ( 23970603 )
2013
47
Vulvovaginitis and balanitis in patients with diabetes treated with dapagliflozin. ( 23806570 )
2013
48
Pseudoepitheliomatous keratotic and micaceous balanitis: a rare condition successfully treated with topical 5-Fluorouracil. ( 24249909 )
2013
49
Pseudoepitheliomatous, keratotic, micaceous balanitis and lichen sclerosus: two sides of the same coin. ( 24005152 )
2013
50
Paediatric balanitis xerotica obliterans: an 8-year experience. ( 22649954 )
2012

Variations for Balanitis

Expression for Balanitis

Search GEO for disease gene expression data for Balanitis.

Pathways for Balanitis

GO Terms for Balanitis

Cellular components related to Balanitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.02 PHB2 SLC5A2 TGM1 TGM2 TGM3

Biological processes related to Balanitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.32 TGM1 TGM3
2 cellular protein modification process GO:0006464 9.26 TGM1 TGM3
3 keratinocyte differentiation GO:0030216 9.16 TGM1 TGM3
4 cell envelope organization GO:0043163 8.96 TGM1 TGM3
5 peptide cross-linking GO:0018149 8.8 TGM1 TGM2 TGM3

Molecular functions related to Balanitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring acyl groups GO:0016746 9.13 TGM1 TGM2 TGM3
2 protein-glutamine gamma-glutamyltransferase activity GO:0003810 8.8 TGM1 TGM2 TGM3

Sources for Balanitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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