MCID: BLN010
MIFTS: 40

Balanitis malady

Reproductive diseases category

Summaries for Balanitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Balanitis (/bæləˈnaɪtɪs/; from Greek: βάλανος balanos \"acorn\") is inflammation of the... more...

MalaCards: Balanitis is related to balanitis xerotica obliterans and squamous cell carcinoma. An important gene associated with Balanitis is SRR (serine racemase), and among its related pathways is Regulation of Insulin Secretion. The compounds n-acetyllactosamine and amide have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and bone.

Aliases & Classifications for Balanitis

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Related Diseases for Balanitis

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17GeneCards, 18GeneDecks
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Diseases related to Balanitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1balanitis xerotica obliterans31.3AKTIP
2squamous cell carcinoma30.3IFI27, ISG20, GAL, MLXIPL, MT-CO2, LGALS3
3herpes simplex30.0ISG20, GGH
4urethritis10.3
5balanoposthitis10.3
6vulvitis10.2
7phimosis10.2
8urethral stricture10.2
9hypospadias10.1
10verrucous carcinoma10.1
11necrobiosis lipoidica10.0
12syphilis10.0
13hepatitis10.0GAL
14colon cancer10.0IFI27, LGALS3, GAL
15mood disorder10.0GGH, GAL, ADRA2A
16neuroendocrine tumor10.0IFI27, GAL, GGH
17diabetes mellitus10.0MLXIPL
18leukemia10.0MLXIPL, IFI27, GGH, ISG20, CTRL, GAL
19adenoma10.0PVR, PTGIS, GGH, GAL, IFI27, LGALS3
20ischemia10.0GAL, PTGIS, LGALS3
21breast cancer10.0LGALS3, MLXIPL, GAL, CTRL, ISG20, IFI27
22adenocarcinoma10.0IFI27, MLXIPL, GAL, PTGIS, LGALS3, ADRA2A
23ipex syndrome10.0GGH, GAL, CTRL, ISG20, PVR
24alzheimer's disease10.0SRR, GAL, CTRL
25glioblastoma multiforme10.0SRR, LGALS3, IFI27
26melanoma10.0LGALS3, GAL, CTRL, ISG20, IFI27
27burkitt's lymphoma10.0GGH, MLXIPL, ISG20, IFI27, LGALS3
28pituitary adenoma10.0IFI27, GAL, LGALS3
29paronychia9.9
30proctitis9.9
31vulvovaginitis9.9
32cicatricial pemphigoid9.9
33pemphigus9.9
34lichen planus9.9
35reactive arthritis9.9
36gonorrhea9.9
37peyronie's disease9.9
38primary syphilis9.9
39adenosquamous carcinoma9.9
40acute conjunctivitis9.9
41arthritis9.9
42conjunctivitis9.9
43cystitis9.9
44fibrosarcoma9.9
45gingival disease9.9
46gingivitis9.9
47hyperglycemia9.9
48in situ carcinoma9.9
49leprosy9.9
50penis squamous cell carcinoma9.9

Graphical network of the top 20 diseases related to Balanitis:



Diseases related to balanitis

Clinical Features for Balanitis

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Drugs & Therapeutics for Balanitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Balanitis

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Anatomical Context for Balanitis

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32MalaCards
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MalaCards organs/tissues related to Balanitis:

32
Skin, Bone marrow, Bone, T cells

Animal Models for Balanitis or affiliated genes

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Publications for Balanitis

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50PubMed
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Articles related to Balanitis:

(show top 50)    (show all 258)
idTitleAuthorsYear
1
Incidence of balanitis xerotica obliterans in boys younger than 10 years presenting with phimosis. (23296396)
2013
2
Differentiation between balanitis and carcinoma in situ using reflectance confocal microscopy. (23325422)
2013
3
Pseudoepitheliomatous keratotic and micaceous balanitis with malignant transformation. (23919054)
2013
4
Granulomatous balanitis after intravesical Bacille Calmette-GuAcrin instillation. (23177394)
2013
5
Complete resolution of Zoon balanitis with photodynamic therapy--a new therapeutic option? (22693017)
2012
6
Syphilitic balanitis of Follmann: three case reports. (21103851)
2011
7
Zoon's plasma cell balanitis: a report of two cases treated with pimecrolimus. (22068766)
2011
8
Noninfectious balanitis in patients attending a sexually transmitted diseases clinic. (19335440)
2009
9
Discordant results with pimecrolimus 1% cream in the treatment of plasma cell balanitis. (18832808)
2009
10
Videodermatoscopy enhances diagnostic capability in psoriatic balanitis. (19925937)
2009
11
Two cases of Zoon's balanitis treated with pimecrolimus 1% cream. (18211499)
2008
12
Treatment of Zoon's balanitis with imiquimod 5% cream. (17679189)
2007
13
Zoon's balanitis in a circumcised man. (17637383)
2007
14
Case of balanitis circumscripta plasmacellularis. (17352729)
2007
15
Is the association between balanitis xerotica obliterans and penile carcinoma underestimated? (16831147)
2006
16
Balanitis caused by Streptococcus pyogenes: a report of two cases. (16176638)
2005
17
Keratoderma blenorrhagica, balanitis and uveitis after HLA-B15 mismatched bone marrow transplantation. (11869956)
2002
18
5-fluorouracil-induced balanitis in a patient with oesophageal carcinoma. (11527289)
2001
19
Connubial allergic contact balanitis due to chlorhexidine. (11422271)
2001
20
Pseudo-epitheliomatous keratotic and micaceous balanitis. (10037403)
1999
21
National guideline for the management of balanitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). (10616394)
1999
22
Balanitis xerotica obliterans complicating hypospadias repair. (10343594)
1999
23
Balanitis and balanoposthitis: a review. (9038655)
1996
24
Staphylococcus-induced toxic shock following balanitis. (7774148)
1995
25
Detection of human papillomavirus types in balanitis xerotica obliterans and other penile conditions. (7590713)
1995
26
Plasma cell balanitis: clinical and histopathological features--response to circumcision. (7750950)
1995
27
Balanitis of Zoon. (2397965)
1990
28
Balanitis. (2702407)
1989
29
Pseudoepitheliomatous micaceous and keratotic balanitis. (3401420)
1988
30
Chronic balanitis owing to pemphigus vegetans. (3806823)
1987
31
Balanitis xerotica obliterans in children. (3735511)
1986
32
Adenosquamous carcinoma of the penis associated with balanitis xerotica obliterans. (3801839)
1986
33
Balanitis as a fixed drug eruption to tetracycline. (3158749)
1985
34
Pseudoepitheliomatous, keratotic, and micaceous balanitis. (7259225)
1981
35
Group B beta-hemolytic streptococci causing balanitis. (6996106)
1980
36
Balanitis caused by group B beta-hemolytic streptococci. (7006119)
1980
37
Balanitis circumscripta plasmacellularis. (7354148)
1980
38
Letter: balanitis and vulvo-vaginitis in sheep. (962743)
1976
39
Syphilitic balanitis of Follmann developing after the appearance of the primary chancre. A case report. (1131680)
1975
40
Letter: Tetracycline balanitis: fixed drug reaction. (4405856)
1974
41
Urethral involvement in balanitis xerotica obliterans. (5420163)
1970
42
DEQUALINIUM AND BALANITIS. (14171106)
1964
43
Treatment of balanitis xerotica obliterans with hydrocortisone injections. (13877396)
1962
44
Vincent's infection of the penis (erosive balanitis); differential diagnosis and report of a case. (15443196)
1950
45
Eruptive fever with involvement of the respiratory tract, conjunctivitis, stomatitis and balanitis; an acute clinical entity, probably of infectious origin; report of twenty cases and review of the literature. (20240868)
1947
46
Balanitis xerotica obliterans associated with chronic gonorrhea. (20279613)
1946
47
Balanitis xerotica obliterans. (20992329)
1946
48
Balanitis xerotica obliterans. (21064999)
1946
49
Erosive and gangrenous balanitis; report of a case. (20988076)
1946
50
SALVARSAN IN EROSIVE BALANITIS. (18736288)
1914

Genetic Variations for Balanitis

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Expression for genes affiliated with Balanitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Balanitis

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Pathways for genes affiliated with Balanitis

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53Reactome
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Pathways related to Balanitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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10.4ADRA2A, PLCB2, MLXIPL

Compounds for genes affiliated with Balanitis

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44Novoseek, 24HMDB, 11DrugBank, 49PharmGKB
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Compounds related to Balanitis according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1n-acetyllactosamine44 2411.6GAL, MLXIPL, LGALS3
2amide4410.6LGALS3, MLXIPL, GAL, CTRL
3lactose44 1111.6GAL, MLXIPL, LGALS3
4gal(beta1-3)galnac4410.5LGALS3, GAL
5polyacrylamide4410.5CTRL, GAL, MLXIPL, LGALS3
6estrogen4410.4ISG20, PHB2, ADRA2A
7lipid4410.4IFI27, GAL, MLXIPL, GGH, PTGIS, LGALS3
8tyrosine4410.4IFI27, ISG20, CTRL, GAL, ITFG1, PTGIS
9mirtazapine49 44 1112.3ADRA2A, GAL
10phosphatidylinositol4410.3LGALS3, PLCB2, GAL, CTRL, IFI27
11calcium44 49 11 2413.2IFI27, CTRL, GAL, MLXIPL, PLCB2, SRR
12phosphoinositide4410.0IFI27, GAL, PLCB2, LGALS3

GO Terms for genes affiliated with Balanitis

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16Gene Ontology
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Cellular components related to Balanitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00573710.1ADRA2A, ISG20, AKTIP, MLXIPL, MINK1, SIAH2

Products for genes affiliated with Balanitis

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Sources for Balanitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet