MCID: BRR013
MIFTS: 27

Barrett Esophagus/esophageal Adenocarcinoma malady

Genetic diseases, Rare diseases, Gastrointestinal diseases categories

Summaries for Barrett Esophagus/esophageal Adenocarcinoma

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NIH Rare Diseases:41 Barrett syndrome, also known as barrett esophagus, is a disorder in which the lining of the esophagus (the tube that carries food from the throat to the stomach) is replaced by tissue that is similar to the lining of the intestine. this process is called intestinal metaplasia. the exact cause of barrett syndrome is not known, but gastroesophageal reflux disease (gerd) is a risk factor for the condition. while barrett syndrome itself does not cause symptoms, the acid reflux associated with gerd often leads to symptoms of heartburn.  less than 1% of people with barrett syndrome develop a rare type of cancer called esophageal adenocarcinoma. treatment of gerd should improve symptoms, and may keep barrett syndrome from getting worse. endoscopic or surgical treatments can be used to treat barrett syndrome with severe dysplasia or cancer. last updated: 3/5/2010

MalaCards based summary: Barrett Esophagus/esophageal Adenocarcinoma, also known as barrett esophagus, is related to esophagitis and adenocarcinoma, and has symptoms including somatic mutation, esophageal carcinoma and barrett esophagus. An important gene associated with Barrett Esophagus/esophageal Adenocarcinoma is CTHRC1 (collagen triple helix repeat containing 1).

OMIM:45 Barrett esophagus, or Barrett metaplasia, describes the phenotypic change of normal esophageal squamous epithelium to a... (614266) more...

Aliases & Classifications for Barrett Esophagus/esophageal Adenocarcinoma

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Barrett Esophagus/esophageal Adenocarcinoma, Aliases & Descriptions:

Name: Barrett Esophagus/esophageal Adenocarcinoma 45 10
Barrett Esophagus 45 9 41 43 60
Barrett's Esophagus with Esophagitis 9 60
Barrett's Ulcer of Esophagus 9 60
Ulcerative Esophagitis 9 60
Barrett's Esophagus 9 20
Barretts Esophagus 11 22
Chronic Peptic Ulcer and Esophagitis Syndrome 41
 
Peptic Ulcer of Esophagus 60
Esophagitis-Peptic Ulcer 41
Columnar-Like Esophagus 41
Barrett's Oesophagus 9
Barretts Syndrome 9
Barrett Syndrome 41
Barrett Ulcer 41
Cle 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Gastrointestinal diseases


External Ids:

OMIM45 614266
Disease Ontology9 DOID:9206
NCIt38 C2891
MeSH33 D001471
ICD9CM27 530.85
ICD1025 K22.7

Related Diseases for Barrett Esophagus/esophageal Adenocarcinoma

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Graphical network of the top 20 diseases related to Barrett Esophagus/esophageal Adenocarcinoma:



Diseases related to barrett esophagus/esophageal adenocarcinoma

Symptoms for Barrett Esophagus/esophageal Adenocarcinoma

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Clinical features from OMIM:

614266

HPO human phenotypes related to Barrett Esophagus/esophageal Adenocarcinoma:

id Description Frequency HPO Source Accession
1 somatic mutation HP:0001428
2 esophageal carcinoma HP:0011459
3 barrett esophagus HP:0100580

Drugs & Therapeutics for Barrett Esophagus/esophageal Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Barrett Esophagus/esophageal Adenocarcinoma

Search NIH Clinical Center for Barrett Esophagus/esophageal Adenocarcinoma

Genetic Tests for Barrett Esophagus/esophageal Adenocarcinoma

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Genetic tests related to Barrett Esophagus/esophageal Adenocarcinoma:

id Genetic test Affiliating Genes
1 Barrett Esophagus20
2 Barrett's Esophagus22

Anatomical Context for Barrett Esophagus/esophageal Adenocarcinoma

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Animal Models for Barrett Esophagus/esophageal Adenocarcinoma or affiliated genes

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Publications for Barrett Esophagus/esophageal Adenocarcinoma

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Variations for Barrett Esophagus/esophageal Adenocarcinoma

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Expression for genes affiliated with Barrett Esophagus/esophageal Adenocarcinoma

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Search GEO for disease gene expression data for Barrett Esophagus/esophageal Adenocarcinoma.

Pathways for genes affiliated with Barrett Esophagus/esophageal Adenocarcinoma

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Compounds for genes affiliated with Barrett Esophagus/esophageal Adenocarcinoma

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GO Terms for genes affiliated with Barrett Esophagus/esophageal Adenocarcinoma

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Cellular components related to Barrett Esophagus/esophageal Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagenGO:00055819.3CTHRC1, MSR1

Products for genes affiliated with Barrett Esophagus/esophageal Adenocarcinoma

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  • Antibodies
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Sources for Barrett Esophagus/esophageal Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet