CLE
MCID: BRR003
MIFTS: 71

Barrett's Esophagus (CLE) malady

Genetic diseases, Rare diseases, Gastrointestinal diseases, Cancer diseases categories
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Summaries for Barrett's Esophagus

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43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Barrett syndrome, also known as barrett esophagus, is a disorder in which the lining of the esophagus (the tube that carries food from the throat to the stomach) is replaced by tissue that is similar to the lining of the intestine. this process is called intestinal metaplasia. the exact cause of barrett syndrome is not known, but gastroesophageal reflux disease (gerd) is a risk factor for the condition. while barrett syndrome itself does not cause symptoms, the acid reflux associated with gerd often leads to symptoms of heartburn.  less than 1% of people with barrett syndrome develop a rare type of cancer called esophageal adenocarcinoma. treatment of gerd should improve symptoms, and may keep barrett syndrome from getting worse. endoscopic or surgical treatments can be used to treat barrett syndrome with severe dysplasia or cancer. last updated: 3/5/2010

MalaCards: Barrett's Esophagus, also known as barrett esophagus, is related to barrett esophagus/esophageal adenocarcinoma and esophageal cancer. An important gene associated with Barrett's Esophagus is CTHRC1 (collagen triple helix repeat containing 1), and among its related pathways are Inhibition of Ribosome Biogenesis by p14(ARF) and TP53 network. The drugs sodium bicarbonate and sodium bicarbonate powder and the compounds acnu and bpde have been mentioned in the context of this disorder. Affiliated tissues include lymph node, liver and testes, and related mouse phenotypes are pigmentation and adipose tissue.

Wikipedia:65 Barrett\'s esophagus (British English: Barrett\'s oesophagus), sometimes called Barrett syndrome,... more...

Aliases & Classifications for Barrett's Esophagus

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8Disease Ontology, 62UMLS, 43NIH Rare Diseases, 20GeneTests, 22GTR, 45Novoseek, 10DISEASES, 58SNOMED-CT, 40NCIt, 35MeSH, 27ICD9CM, 25ICD10
See all sources

Classifications:



Aliases & Descriptions:

barrett's esophagus 8
barrett esophagus 8 43 20 22 45 62
barrett's ulcer of esophagus 8 62
chronic peptic ulcer and esophagitis syndrome 43
barrett's esophagus with esophagitis 8
gastroesophageal reflux disease 62
peptic ulcer of esophagus 62
esophagitis-peptic ulcer 43
columnar-like esophagus 43
ulcerative esophagitis 8
esophageal carcinoma 62
barrett's oesophagus 8
barretts esophagus 10
barretts syndrome 8
barrett syndrome 43
barrett ulcer 43
cle 8


External Ids:

Disease Ontology8 DOID:9206
NCIt40 C2891
MeSH35 D001471
ICD9CM27 530.85
ICD1025 K22.7

Related Diseases for Barrett's Esophagus

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17GeneCards, 18GeneDecks
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Diseases related to Barrett's Esophagus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 103)
idRelated DiseaseScoreTop Affiliating Genes
1barrett esophagus/esophageal adenocarcinoma30.9CTHRC1, ASCC1
2esophageal cancer30.7CDKN2A, GSTP1, TP53, PTGS2
3adenocarcinoma30.6FGF1, CTNNA1, CDKN2A, CDX2, GSTP1, MUC2
4esophagitis30.4SOD2, CDX2
5tubular adenocarcinoma30.2MUC2, CTNNA1, CDX2
6gastritis30.0CDX2, PTGS2, TP53
7melanoma29.9CDKN2A, CDX2, CTNNA1, MGMT, TERC, CYP1A1
8prune belly syndrome10.4
9esophageal atresia10.4
10gastroesophageal reflux disease10.3
11mungan syndrome10.3
12high-grade dysplasia in patients with barrett esophagus10.3
13cutaneous lupus erythematosus10.3
14lupus erythematosus10.3
15duodenogastric reflux10.2
16bile reflux10.2
17achalasia10.2
18eosinophilia10.2
19obesity10.2
20visceral myopathy10.2
21endotheliitis10.2
22adenocarcinoma in situ10.1CDKN2A
23actinic keratosis10.1TP53
24juvenile polyposis syndrome10.1APC
25turcot syndrome10.1APC
26oropharyngeal cancer, adult10.1CDKN2A, TP53
27li-fraumeni syndrome10.1TP53, CDKN2A
28nasopharynx carcinoma10.1CDKN2A, TP53
29familial colorectal cancer10.1APC, CDKN2A
30bladder transitional cell carcinoma10.1GSTP1, TP53
31bile duct carcinoma10.1CDKN2A, MUC2
32lynch syndrome10.1TP53, APC
33leukemia, acute nonlymphocytic10.1FGF1, GSTP1
34oligodendroglioma10.1MGMT, CDKN2A
35anaplastic oligodendroglioma10.1CDKN2A, MGMT
36cervical intraepithelial neoplasia10.1CDKN2A, TERC
37acute lymphoblastic leukemia, childhood10.0CDKN2A, CYP1A1, GSTP1
38diphtheria10.0
39congenital lobar emphysema10.0
40anaplastic astrocytoma10.0CDKN2A, TP53, MGMT
41bladder carcinoma in situ10.0PTGS2, GSTP1, CDKN2A, TP53
42eye disease10.0FGF1, SOD2
43leukoplakia10.0CYP1A1, MGMT, TERC
44malignant mesothelioma10.0CTNNA1, CDKN2A, SOD2
45breast cancer10.0APC, CYP1A1, PTGS2
46malignant pleural mesothelioma10.0SOD2, CTNNA1
47pseudomyxoma peritonei10.0CDX2, MUC2
48laryngeal benign neoplasm10.0GSTP1, MUC2, CYP1A1
49xeroderma pigmentosum10.0TP53, MGMT, CYP1A1
50cervical adenocarcinoma10.0CDX2, CDKN2A

Graphical network of the top 20 diseases related to Barrett's Esophagus:



Diseases related to barrett's esophagus

Symptoms for Barrett's Esophagus

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Genetic Tests for Barrett's Esophagus

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20GeneTests, 22GTR
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Genetic tests related to Barrett's Esophagus:

id Genetic test Affiliating Genes
1 Barrett Esophagus20
2 Barrett's Esophagus22

Anatomical Context for Barrett's Esophagus

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33MalaCards
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MalaCards organs/tissues related to Barrett's Esophagus:

33
Lymph node, Liver, Testes

Animal Models for Barrett's Esophagus or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Barrett's Esophagus:

37 (show all 23)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.1TERC, APC, TP53, SOD2, CDKN2A
2MP:00053758.8TERC, PTGS2, APC, TP53, SOD2
3MP:00053708.5CYP1A1, PTGS2, APC, TP53, SOD2, CDKN2A
4MP:00053918.4TERC, PTGS2, APC, TP53, SOD2, CDKN2A
5MP:00030128.3MGMT, CYP1A1, PTGS2, APC, TP53, CDKN2A
6MP:00053698.1TERC, PTGS2, APC, TP53, SOD2, CDKN2A
7MP:00053718.1CTNNA1, CDX2, TP53, APC, TERC
8MP:00107718.0TERC, PTGS2, APC, TP53, SOD2, GSTP1
9MP:00053897.9TERC, PTGS2, APC, TP53, SOD2, CDX2
10MP:00053817.9TERC, PTGS2, APC, TP53, MUC2, CDX2
11MP:00028737.7CYP1A1, PTGS2, APC, TP53, CDX2, CTHRC1
12MP:00053877.7TERC, CYP1A1, PTGS2, APC, TP53, SOD2
13MP:00053907.6TERC, PTGS2, APC, TP53, CDX2, CDKN2A
14MP:00053807.6TERC, PTGS2, APC, TP53, CDX2, CDKN2A
15MP:00036317.6TERC, PTGS2, APC, TP53, SOD2, CDKN2A
16MP:00053977.5TERC, CYP1A1, PTGS2, APC, TP53, SOD2
17MP:00053846.9TERC, PTGS2, APC, TP53, SOD2, MUC2
18MP:00053796.9TERC, MGMT, PTGS2, APC, TP53, MUC2
19MP:00053856.8TERC, CYP1A1, PTGS2, APC, TP53, SOD2
20MP:00053786.2TERC, CYP1A1, PTGS2, APC, TP53, SOD2
21MP:00020066.2CTNNA1, TERC, MGMT, PTGS2, APC, TP53
22MP:00053766.0APC, PTGS2, CYP1A1, MGMT, TERC, TP53
23MP:00107686.0TERC, MGMT, CYP1A1, PTGS2, APC, TP53

Publications for Barrett's Esophagus

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52PubMed
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Articles related to Barrett's Esophagus:

(show top 50)    (show all 798)
idTitleAuthorsYear
1
Barrett's esophagus is frequently overdiagnosed in clinical practice: results of the Barrett's Esophagus Endoscopic Revision (BEER) study. (24262638)
2013
2
Role of interleukin-6 in Barrett's esophagus pathogenesis. (23613623)
2013
3
Radiofrequency ablation and endoscopic mucosal resection for dysplastic barrett's esophagus and early esophageal adenocarcinoma: outcomes of the UK National Halo RFA Registry. (23542069)
2013
4
Oral bisphosphonates and the risk of Barrett's esophagus: case-control analysis of US veterans. (23857477)
2013
5
Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma. (23466711)
2013
6
Evaluation of Barrett's esophagus with CK7, CK20, p53, Ki67, and COX2 expressions using chromoendoscopical examination. (22591041)
2013
7
Barrett's Esophagus Suspected at Endoscopy but No Specialized Intestinal Metaplasia on Biopsy, What's Next? (24343550)
2013
8
The molecular changes driving the carcinogenesis in Barrett's esophagus: which came first, the chicken or the egg? (23290822)
2013
9
Cellular origin of Barrett's esophagus: controversy and therapeutic implications. (22537611)
2012
10
Barrett's Esophagus: Emerging Knowledge and Management Strategies. (22701199)
2012
11
Hiatal hernia, Barrett's esophagus, and long-term symptom control after laparoscopic fundoplication for gastroesophageal reflux. (22648102)
2012
12
Aberrantly methylated PKP1 in the progression of Barrett's esophagus to esophageal adenocarcinoma. (22170739)
2012
13
Management of high-grade dysplasia and intramucosal adenocarcinoma in Barrett's esophagus. (22507878)
2012
14
Fluorescence in situ hybridization mapping of esophagectomy specimens from patients with Barrett's esophagus with high-grade dysplasia or adenocarcinoma. (21820152)
2012
15
Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett's Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography. (22844274)
2012
16
Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression. (22503981)
2012
17
On bioptic protocol after laparoscopic Nissen-Rossetti fundoplication in patients with Barrett's esophagus. (23232488)
2012
18
Do transcription factors hold the key to understanding the development of Barrett's esophagus? (22367064)
2012
19
Randomized crossover study comparing efficacy of transnasal endoscopy with that of standard endoscopy to detect Barrett's esophagus. (22421496)
2012
20
Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants. (22715394)
2012
21
Focal endoscopic mucosal resection before radiofrequency ablation is equally effective and safe compared with radiofrequency ablation alone for the eradication of Barrett's esophagus with advanced neoplasia. (22732872)
2012
22
Time to burn? Endoscopic ablation for Barrett's esophagus. (21708153)
2011
23
Barrett's esophagus: natural history. (21950819)
2011
24
Malignant potential of Barrett's esophagus: special reference to HDAC-1 and MTA-1 expression. (21661415)
2011
25
Are we ready for gender-based guidelines for Barrett's esophagus screening? (22033181)
2011
26
Lifetime alcohol consumption and risk of Barrett's Esophagus. (21427711)
2011
27
Management of cancer risk in Barrett's esophagus. (21592226)
2011
28
Barrett's esophagus: treatments of adenocarcinomas II. (21950818)
2011
29
Should we screen patients for Barrett's esophagus? Yes: men with long-standing reflux symptoms should be screened with endoscopy. (21568246)
2011
30
miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. (21448356)
2011
31
Understanding cancer incidence in Barrett's esophagus: light at the end of the tunnel. (21680911)
2011
32
Expression of IFN-I^ and IL-4 in the esophageal mucosa of patients with reflux esophagitis and Barrett's esophagus and their relationship with endoscopic and histologic grading. (21479676)
2011
33
Genome-wide catalogue of chromosomal aberrations in barrett's esophagus and esophageal adenocarcinoma: a high-density single nucleotide polymorphism array analysis. (20651033)
2010
34
Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia. (19491850)
2009
35
Alcohol drinking and the risk of Barrett's esophagus and esophageal adenocarcinoma. (19236968)
2009
36
MicroRNA expression signatures in Barrett's esophagus and esophageal adenocarcinoma. (19737949)
2009
37
Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. (19417022)
2009
38
Expression of EpCam and villin in Barrett's esophagus and in gastric cardia. (18688077)
2008
39
Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus. (18005197)
2008
40
Acid and bile reflux in erosive reflux disease, non-erosive reflux disease and Barrett's esophagus. (18613384)
2008
41
Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. (17849424)
2008
42
High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model. (17868414)
2007
43
Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma. (17585859)
2007
44
The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophagus and patients with Barrett's-associated adenocarcinoma. (16172218)
2005
45
Does chemoprevention of Barrett's esophagus using acid suppression and/or COX-2 inhibition prevent neoplastic progression? (12478242)
2002
46
Parathyroid hormone-related protein production by adenocarcinoma in Barrett's esophagus patient with dermatomyositis. (11478513)
2001
47
Cytokeratin subsets for distinguishing Barrett's esophagus from intestinal metaplasia in the cardia using endoscopic biopsy specimens. (11374671)
2001
48
Adenocarcinoma in situ in Barrett's esophagus with stricture of 10-yr duration: a cytological diagnosis. (8759681)
1996
49
Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model. (8903332)
1996
50
TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus. (7523212)
1994

Variations for Barrett's Esophagus

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Expression for genes affiliated with Barrett's Esophagus

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Barrett's Esophagus

Search GEO for disease gene expression data for Barrett's Esophagus.

Pathways for genes affiliated with Barrett's Esophagus

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Sources:
50PathCards, 53QIAGEN, 38NCBI BioSystems Database, 55Reactome, 51PharmGKB, 60Thomson Reuters, 30KEGG, 12EMD Millipore, 5Cell Signaling Technology
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Pathways related to Barrett's Esophagus according to GeneCards/GeneDecks:

(show all 25)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9TP53, CDKN2A
2
Show member pathways
9.9TP53, CDKN2A
39.9CDKN2A, TP53
49.9GSTP1, PTGS2
5
Show member pathways
9.8SOD2, GSTP1
69.7GSTP1, CYP1A1
79.7SOD2, CYP1A1
8
Show member pathways
9.6GSTP1, MGMT
9
Show member pathways
9.5CDKN2A, GSTP1, SOD2
109.5PTGS2, APC, TP53
11
Show member pathways
9.4CYP1A1, PTGS2, GSTP1
129.4GSTP1, PTGS2, CYP1A1
139.3MGMT, APC, TP53
149.3PTGS2, APC, TP53, CDKN2A
15
Show member pathways
9.2FGF1, CDKN2A, TP53, PTGS2
16
Show member pathways
DNA damage response (only ATM dependent)38
Wnt Signaling Pathway and Pluripotency38
9.2APC, TP53, SOD2, CDKN2A
17
Show member pathways
Signal transduction PTEN pathway60
9.2APC, TP53, CTNNA1
18
Show member pathways
Signaling Pathways in Glioblastoma38
9.2TP53, GSTP1, CDKN2A, FGF1
199.1FGF1, TP53, APC, PTGS2
20
Show member pathways
9.1CDKN2A, GSTP1, TP53, MGMT
219.1FGF1, CTNNA1, APC
229.0MGMT, APC, TP53, CDKN2A
238.9PTGS2, APC, TP53, CTNNA1
24
Show member pathways
8.2PTGS2, APC, TP53, CDKN2A, CTNNA1, FGF1
257.9FGF1, CTNNA1, CDKN2A, GSTP1, TP53, APC

Compounds for genes affiliated with Barrett's Esophagus

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Sources:
45Novoseek, 11DrugBank, 24HMDB, 51PharmGKB, 29IUPHAR, 3BitterDB, 61Tocris Bioscience
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Compounds related to Barrett's Esophagus according to GeneCards/GeneDecks:

(show top 50)    (show all 123)
idCompoundScoreTop Affiliating Genes
1acnu459.7MGMT, TP53, CDKN2A
2bpde459.5CYP1A1, GSTP1, TP53
3sulindac45 1110.4CYP1A1, TP53, APC, PTGS2
45-methylcytosine45 2410.4CDKN2A, TP53, APC, MGMT
5sodium bisulfite459.4APC, GSTP1, CDKN2A, MGMT
6adriamycin459.4CDKN2A, TP53, GSTP1, SOD2, TERC
77,12-dimethylbenz(a)anthracene459.3APC, MGMT, CYP1A1, CDKN2A
8chlorambucil45 1110.3GSTP1, TP53, MGMT
98-oxoguanine459.2APC, MGMT, SOD2
10sulforaphane459.2CYP1A1, GSTP1, PTGS2, MGMT
11oxaliplatin45 51 1111.2GSTP1, CYP1A1, MGMT, TP53
12irinotecan45 51 1111.2GSTP1, CDKN2A, PTGS2, MGMT, TP53
13bcnu459.2MGMT, TP53, SOD2, GSTP1, CDKN2A
14mitomycin c459.2MGMT, TP53, SOD2, GSTP1
15agar459.1FGF1, TERC, GSTP1, CDKN2A, SOD2
16o6-methylguanine459.1MGMT, GSTP1, CDKN2A, APC, TP53
17guanine45 24 1111.0MGMT, APC, TP53, SOD2, TERC
18folate459.0GSTP1, SOD2, APC, MGMT, CDKN2A
19tamoxifen45 51 29 1111.9CYP1A1, TERC, TP53, FGF1, SOD2
20crcs458.9MGMT, APC, TP53, MUC2, CDKN2A
21azathioprine45 3 51 1111.9MGMT, MUC2, GSTP1, CDKN2A
22dmso458.9CYP1A1, GSTP1, MUC2, SOD2, TERC
23cyclophosphamide45 51 1110.9CYP1A1, GSTP1, MGMT, SOD2, TP53
24n acetylcysteine458.9TP53, CDKN2A, SOD2, CYP1A1, GSTP1, PTGS2
25doxorubicin45 51 1110.8CDKN2A, GSTP1, SOD2, TP53, MGMT, TERC
26etoposide45 51 61 1111.8GSTP1, SOD2, TP53, MGMT, PTGS2, TERC
27thymidylate458.8TP53, MGMT, CDKN2A, GSTP1
28methotrexate51 45 1110.8GSTP1, CDKN2A, MGMT, SOD2, MUC2
29norepinephrine45 24 1110.6APC, TERC, CYP1A1, FGF1, SOD2
30h2o2458.6CDKN2A, SOD2, GSTP1, TP53, FGF1, CYP1A1
31testosterone45 61 24 1111.5FGF1, CDKN2A, SOD2, APC, CYP1A1, GSTP1
32egcg458.4CYP1A1, PTGS2, CDKN2A, GSTP1, SOD2, TP53
33cycloheximide458.4SOD2, FGF1, CDKN2A, CYP1A1, PTGS2, APC
345fluorouracil458.4GSTP1, MUC2, SOD2, TP53, MGMT, TERC
3512-o-tetradecanoylphorbol 13-acetate458.3FGF1, SOD2, MGMT, MUC2, CTNNA1
36genistein45 29 61 3 24 1113.3SOD2, PTGS2, CYP1A1, MGMT, FGF1, CDKN2A
37cisplatin45 51 61 1111.1SOD2, TERC, CDKN2A, CYP1A1, PTGS2, GSTP1
38butyrate458.1CDKN2A, SOD2, CDX2, TERC, GSTP1, TP53
39paclitaxel45 51 1110.1CYP1A1, CDKN2A, GSTP1, SOD2, TP53, MGMT
40curcumin458.1GSTP1, SOD2, TP53, PTGS2, CYP1A1, MGMT
41actinomycin d458.0PTGS2, TP53, CDKN2A, CYP1A1, SOD2, MUC2
42dexamethasone45 51 29 1111.0FGF1, MGMT, CYP1A1, MUC2, PTGS2, SOD2
43cysteine457.5SOD2, MGMT, GSTP1, CDX2, FGF1, MUC2
44retinoic acid45 248.5TP53, GSTP1, CDKN2A, TERC, MUC2, APC
45progesterone45 29 61 24 1111.4MUC2, CDX2, TP53, TERC, MGMT, CYP1A1
46vegf457.4FGF1, CTNNA1, CYP1A1, CDKN2A, GSTP1, SOD2
475-aza-2deoxycytidine457.2APC, CDKN2A, MGMT, TP53, MUC2, GSTP1
48oligonucleotide456.8TP53, FGF1, CTNNA1, APC, MGMT, TERC
49estrogen456.4TERC, MUC2, MGMT, TP53, APC, PTGS2
50paraffin456.2TERC, MGMT, FGF1, APC, CTNNA1, CDKN2A

GO Terms for genes affiliated with Barrett's Esophagus

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Sources:
16Gene Ontology
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Cellular components related to Barrett's Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:0166049.9CDKN2A, TP53
2mitochondrionGO:0057398.5CDKN2A, GSTP1, SOD2, TP53, CYP1A1

Biological processes related to Barrett's Esophagus according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:09039910.2CDKN2A, TP53
2response to manganese ionGO:01004210.2PTGS2, SOD2
3positive regulation of cell cycle arrestGO:07115810.1TP53, CDKN2A
4negative regulation of MAPK cascadeGO:04340910.0GSTP1, APC
5negative regulation of cyclin-dependent protein serine/threonine kinase activityGO:04573610.0CDKN2A, APC
6release of cytochrome c from mitochondriaGO:00183610.0SOD2, TP53
7hydrogen peroxide biosynthetic processGO:05066510.0CYP1A1, SOD2
8response to hyperoxiaGO:0550939.9SOD2, CYP1A1
9response to gamma radiationGO:0103329.9SOD2, TP53
10negative regulation of neuroblast proliferationGO:0074069.9TP53, CTNNA1
11negative regulation of fibroblast proliferationGO:0481479.9GSTP1, SOD2, TP53
12positive regulation of nitric oxide biosynthetic processGO:0454299.8SOD2, PTGS2
13T cell differentiation in thymusGO:0330779.8TP53, APC
14cellular response to ionizing radiationGO:0714799.8MGMT, TP53
15cell cycle arrestGO:0070509.8CDKN2A, TP53, APC
16response to antibioticGO:0466779.6CYP1A1, TP53
17response to lipopolysaccharideGO:0324969.6CYP1A1, PTGS2, SOD2
18cellular response to UVGO:0346449.6PTGS2, TP53
19negative regulation of cell proliferationGO:0082859.2PTGS2, APC, TP53, SOD2, CDKN2A
20response to drugGO:0424939.2SOD2, PTGS2, CYP1A1, MGMT

Molecular functions related to Barrett's Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MDM2/MDM4 family protein bindingGO:0973719.9CDKN2A, TP53
2oxygen bindingGO:0198259.7SOD2, CYP1A1
3gamma-catenin bindingGO:0452959.4CTNNA1, APC
4cadherin bindingGO:0452969.2CTNNA1, APC

Products for genes affiliated with Barrett's Esophagus

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  • Antibodies
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Sources for Barrett's Esophagus

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet