MCID: BRT043
MIFTS: 34

Bartonellosis

Categories: Infectious diseases

Aliases & Classifications for Bartonellosis

MalaCards integrated aliases for Bartonellosis:

Name: Bartonellosis 12 14
Bartonella Infections 42 69
Bartonella Infectious Disease 12
Rochalimaea Infection 12
Bartonelliasis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11102
ICD10 33 A44 A44.9
ICD9CM 35 088.0
MeSH 42 D001474
NCIt 47 C84586
UMLS 69 C0004771

Summaries for Bartonellosis

Disease Ontology : 12 A primary bacterial infectious disease that is caused by the bacteria of the genus Bartonella.

MalaCards based summary : Bartonellosis, also known as bartonella infections, is related to carrion's disease and cat-scratch disease. An important gene associated with Bartonellosis is CD40LG (CD40 Ligand), and among its related pathways/superpathways is Mitochondrial protein import. The drugs Azithromycin and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include liver, bone and kidney, and related phenotype is Decreased viability with cisplatin.

Wikipedia : 72 Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella.Bartonella species... more...

Related Diseases for Bartonellosis

Diseases related to Bartonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
id Related Disease Score Top Affiliating Genes
1 carrion's disease 11.8
2 cat-scratch disease 11.7
3 bacillary angiomatosis 11.1
4 trench fever 11.1
5 chronic duodenal ileus 10.5 CD40LG HTRA1
6 leiomyosarcoma 10.5 CD40LG HSPD1
7 pancreatic vasoactive intestinal peptide producing tumor 10.5 CD40LG HSPD1
8 basilar artery occlusion 10.4 CD40LG HSPD1
9 tuberculoid leprosy 10.4 CD40LG HSPD1
10 compensatory emphysema 10.4 CD40LG HSPD1
11 extrahepatic bile duct adenocarcinoma 10.3 CD40LG HSPD1
12 tick-borne encephalitis 10.3 CD40LG EEA1
13 uterine adnexa cancer 10.3 CD40LG HSPD1
14 dracunculiasis 10.2 CD40LG CS
15 opportunistic bacterial infectious disease 10.2 CD40LG HSPD1
16 kaposi sarcoma 10.2 CD40LG HSPD1
17 lymphoma, malt, somatic 10.1 CD40LG HSPD1
18 mineral metabolism disease 10.1 ATR CD40LG HSPD1
19 bacterial exanthem 10.0 HSPD1 HSPE1
20 equatorial staphyloma 10.0 HSPD1 HSPE1
21 neuroretinitis 10.0
22 spastic ataxia 3, autosomal recessive 9.9 HSPD1 HSPE1
23 babesiosis 9.9
24 keratomalacia 9.9 CD40LG HSPD1
25 amyotrohpic lateral sclerosis type 22 9.9 ATR HSPE1
26 angiomatosis 9.8
27 ehrlichiosis 9.8
28 hyperinsulinemic hypoglycemia 9.7
29 plague 9.7
30 kidney disease 9.7
31 macular holes 9.7
32 iridocyclitis 9.7
33 yellow fever 9.7
34 hepatitis 9.7
35 hypoglycemia 9.7
36 thrombocytopenia 9.7
37 uveitis 9.7
38 chlamydia 9.2 CD40LG CS EEA1 HSPD1 HTRA1
39 restless legs syndrome 9.1 ASXL3 CD40LG HSPD1 HSPE1
40 spotted fever 6.8 ASB14 ASXL3 ATR CD40LG CS EEA1

Graphical network of the top 20 diseases related to Bartonellosis:



Diseases related to Bartonellosis

Symptoms & Phenotypes for Bartonellosis

GenomeRNAi Phenotypes related to Bartonellosis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with cisplatin GR00101-A-4 8.62 ASXL3 ATR

Drugs & Therapeutics for Bartonellosis

Drugs for Bartonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3 Anti-Inflammatory Agents Phase 4
4 Antineoplastic Agents, Hormonal Phase 4
5 glucocorticoids Phase 4
6 Hormone Antagonists Phase 4
7 Hormones Phase 4
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
9 Anti-Bacterial Agents Phase 3
10 Anti-Infective Agents Phase 3
11 Gentamicins Phase 3
12 Antibodies
13 Immunoglobulins
14 Liver Extracts

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
2 Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis Recruiting NCT03132116 Phase 3 gentamicin;placebo
3 Bartonella in Liver Transplant Patients Recruiting NCT02595710

Search NIH Clinical Center for Bartonellosis

Cochrane evidence based reviews: bartonella infections

Genetic Tests for Bartonellosis

Anatomical Context for Bartonellosis

MalaCards organs/tissues related to Bartonellosis:

39
Liver, Bone, Kidney, Bone Marrow

Publications for Bartonellosis

Articles related to Bartonellosis:

(show all 41)
id Title Authors Year
1
Bartonellosis in Chronic Kidney Disease: An Unrecognized and Unsuspected Diagnosis. ( 28884961 )
2017
2
Bartonellosis, One Health and all creatures great and small. ( 28133871 )
2017
3
Ocular Bartonellosis. ( 28778273 )
2017
4
Clinical Profile and Visual Outcome of Ocular Bartonellosis in Malaysia. ( 28265290 )
2017
5
Bartonellosis ( 28613624 )
2017
6
Acute Unilateral Vision Loss in a Female Adolescent Due to Ocular Bartonellosis. ( 28398939 )
2017
7
Role of Whole-Body MR with DWIBS in child's Bartonellosis. ( 27598022 )
2016
8
Ultrasound imaging as the basis of a clinical diagnosis of systemic bartonellosis in a patient after bone marrow transplantation. A case report. ( 27446604 )
2016
9
Neuroretinitis in ocular bartonellosis. ( 25453244 )
2015
10
Ocular bartonellosis in transplant recipients: two case reports and review of the literature. ( 26146758 )
2015
11
Clinical determinants of Lyme borreliosis, babesiosis, bartonellosis, anaplasmosis, and ehrlichiosis in an Australian cohort. ( 25565883 )
2015
12
Hyperinsulinemic hypoglycemia syndrome in 2 dogs with bartonellosis. ( 24934703 )
2014
13
Bartonellosis: one health perspectives for an emerging infectious disease. ( 24936029 )
2014
14
Risk factors for human lice and bartonellosis among the homeless, San Francisco, California, USA. ( 25280380 )
2014
15
Neuroretinitis in ocular bartonellosis: a case series. ( 25120352 )
2014
16
Treatment outcomes of human bartonellosis: a systematic review and meta-analysis. ( 23602630 )
2013
17
Macular hole: a rare complication of ocular bartonellosis. ( 23681239 )
2013
18
Cryptogenic hepatitis and bartonellosis. ( 22307338 )
2012
19
Feline bartonellosis: we're just scratching the surface. ( 22918842 )
2012
20
Paradoxical response in ocular bartonellosis. ( 22057809 )
2012
21
Chronic Bartonellosis in cats: what are the potential implications? ( 22918844 )
2012
22
Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia. ( 22267937 )
2011
23
Bartonellosis in cats: a role in uveitis? ( 21923819 )
2011
24
Bartonellosis diagnosis requires careful evaluation. ( 20835501 )
2010
25
Disseminated bartonellosis presenting as neuroretinitis in a young adult with human immunodeficiency virus infection. ( 20216243 )
2010
26
Bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings. ( 20230432 )
2010
27
Flea-associated zoonotic diseases of cats in the USA: bartonellosis, flea-borne rickettsioses, and plague. ( 20185369 )
2010
28
Feline bartonellosis. ( 20933137 )
2010
29
Bartonellosis causing bilateral Leber neuroretinitis: a case report. ( 19253255 )
2009
30
Feline bartonellosis and cat scratch disease. ( 18295347 )
2008
31
Cat-scratch disease (ocular bartonellosis) presenting as bilateral recurrent iridocyclitis. ( 15714406 )
2005
32
Killed in action: microbiologists and clinicians as victims of their occupation. Part 2: Yellow fever and bartonellosis. ( 16128394 )
2005
33
Carrion's disease (Bartonellosis bacilliformis) confirmed by histopathology in the High Forest of Peru. ( 15286824 )
2004
34
Concurrent bartonellosis and babesiosis in a dog with persistent thrombocytopenia. ( 14621218 )
2003
35
Bartonellosis (CarriA^n's disease) in the modern era. ( 11512081 )
2001
36
Cat scratch disease (bartonellosis) mimicking an SLE flare. ( 11787880 )
2001
37
The expanding spectrum of Bartonella infections: I. Bartonellosis and trench fever. ( 9002093 )
1997
38
Bacillary angiomatosis, cat-scratch disease, and bartonellosis: what's the connection? ( 9248882 )
1997
39
Clinical, histologic, microbiologic, and biochemical characterization of the causative agent of bacillary (epithelioid) angiomatosis: a rickettsial illness with features of bartonellosis. ( 1919046 )
1991
40
A history of bartonellosis (CarriA^n's disease). ( 4876803 )
1968
41
Penicillin therapy in human bartonellosis (Carrion's disease). ( 21007299 )
1945

Variations for Bartonellosis

Expression for Bartonellosis

Search GEO for disease gene expression data for Bartonellosis.

Pathways for Bartonellosis

Pathways related to Bartonellosis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.42 CS HSPD1

GO Terms for Bartonellosis

Cellular components related to Bartonellosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 mitochondrial matrix GO:0005759 8.8 CS HSPD1 HSPE1

Biological processes related to Bartonellosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.32 HSPD1 HSPE1
2 response to unfolded protein GO:0006986 9.26 HSPD1 HSPE1
3 B cell proliferation GO:0042100 9.16 CD40LG HSPD1
4 positive regulation of interleukin-12 production GO:0032735 8.96 CD40LG HSPD1
5 positive regulation of interleukin-10 production GO:0032733 8.62 CD40LG HSPD1

Molecular functions related to Bartonellosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 8.62 HSPD1 HSPE1

Sources for Bartonellosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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